Current Opinion in Clinical Nutrition and Metabolic Care最新文献_第8页

Editorial: unravelling the trifecta: obesity, cancer, and DNA damage. 社论：揭开肥胖、癌症和 DNA 损伤三部曲的神秘面纱。

IF 3 3区医学

Current Opinion in Clinical Nutrition and Metabolic Care Pub Date : 2024-07-01 Epub Date: 2024-06-06 DOI: 10.1097/MCO.0000000000001040

Anastasia Z Kalea, Dorothy Klimis-Zacas

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Lactose malabsorption and intolerance in older adults. 老年人乳糖吸收不良和不耐受。

IF 3.1 3区医学

Current Opinion in Clinical Nutrition and Metabolic Care Pub Date : 2024-07-01 Epub Date: 2024-06-06 DOI: 10.1097/MCO.0000000000001045

Antonella Gallo, Emanuele Marzetti, Simona Pellegrino, Massimo Montalto

{"title":"Lactose malabsorption and intolerance in older adults.","authors":"Antonella Gallo, Emanuele Marzetti, Simona Pellegrino, Massimo Montalto","doi":"10.1097/MCO.0000000000001045","DOIUrl":"10.1097/MCO.0000000000001045","url":null,"abstract":"Purpose of review: Lactose malabsorption and intolerance are very common conditions. However, their optimal approach, including the diagnostic assessment, remains a matter of debate, especially in advanced age. In this brief review, we focused on current knowledge, concerns, and impact in clinical practice of lactose malabsorption and intolerance in elderly.Recent findings: Older adults are at high risk of malnutrition, owing to frequent occurrence of cognitive impairment, loss of appetite, dysphagia, and poor oral health. A significant decrease in the consumption of dairy products may lead to inadequate intake of high-quality protein and minerals, with a consequent impact on muscle and bone health. Testing for lactose malabsorption may be challenging in older adults, if not useless. Instead, a detailed clinical evaluation should always be pursued to identify both lactose intolerance and all confounding factors mimicking the same clinical picture.Summary: The management of lactose malabsorption and intolerance in older adults deserves a personalized approach. Because of the importance of maintaining an adequate nutritional status in this age group, efforts should be put forth to avoid excessively restrictive diets.","PeriodicalId":10962,"journal":{"name":"Current Opinion in Clinical Nutrition and Metabolic Care","volume":" ","pages":"333-337"},"PeriodicalIF":3.1,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11155274/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141247121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Carbohydrates in the context of metabolic diseases. 代谢性疾病中的碳水化合物。

IF 3.1 3区医学

Current Opinion in Clinical Nutrition and Metabolic Care Pub Date : 2024-07-01 Epub Date: 2024-06-06 DOI: 10.1097/MCO.0000000000001041

Lia Bally, Leonidas G Karagounis

引用次数: 0

Nourishing the gut: the impact of diet on host-gut microbiota interaction. 滋养肠道：饮食对宿主-肠道微生物群相互作用的影响。

IF 3.1 3区医学

Current Opinion in Clinical Nutrition and Metabolic Care Pub Date : 2024-07-01 Epub Date: 2024-01-17 DOI: 10.1097/MCO.0000000000001009

Davide Masi, Tiphaine Le Roy, Solia Adriouch, Karine Clément

{"title":"Nourishing the gut: the impact of diet on host-gut microbiota interaction.","authors":"Davide Masi, Tiphaine Le Roy, Solia Adriouch, Karine Clément","doi":"10.1097/MCO.0000000000001009","DOIUrl":"10.1097/MCO.0000000000001009","url":null,"abstract":"Purpose of review: Understanding the spectrum of drivers that influence the gut microbiome (GM) remains a crucial field of investigation. Among these factors, diet has received particular attention, as it could explain up to 20% of the variability in GM composition between individuals. This review focuses on the complex relationships between different dietary patterns and GM in humans, based on recent findings.Recent findings: Current evidence underscores the multifaceted impact of diet on GM richness, diversity, and overall composition. Key contributing factors encompass dietary habits, nutritional interventions, food quality and variety, macronutrient distribution, timing of feeding, and selective exclusion of certain foods.Summary: The intricate interplay between diet and GM is of fundamental importance in shaping the interaction between the host and the environment. Further understanding the causal impact of diet on GM has promising potential for the advancement of strategies to promote health and mitigate cardio-metabolic disease risks through dietary interventions.Graphical abstract: http://links.lww.com/COCN/A21.","PeriodicalId":10962,"journal":{"name":"Current Opinion in Clinical Nutrition and Metabolic Care","volume":" ","pages":"361-371"},"PeriodicalIF":3.1,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139520398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Plant proteins: are they a good alternative to animal proteins in older people? 植物蛋白：它们是老年人动物蛋白的良好替代品吗？

IF 3.1 3区医学

Current Opinion in Clinical Nutrition and Metabolic Care Pub Date : 2024-07-01 Epub Date: 2024-03-01 DOI: 10.1097/MCO.0000000000001026

Lina Toutirais, Carole Vaysse, Marine Gueugneau, Stephane Walrand

{"title":"Plant proteins: are they a good alternative to animal proteins in older people?","authors":"Lina Toutirais, Carole Vaysse, Marine Gueugneau, Stephane Walrand","doi":"10.1097/MCO.0000000000001026","DOIUrl":"10.1097/MCO.0000000000001026","url":null,"abstract":"Purpose of review: This review provides the latest insight into the impact of consuming plant-based protein for older people.Recent findings: According to the latest data, a healthy diet rich in plant-based-protein-rich-food could promote healthy aging. This health effect is partly because of the amino acid composition of proteins, as well as to the important constituents such as fiber and bioactive compounds found in the matrix. Furthermore, even though animal protein is more effective at stimulating muscle protein synthesis, a high consumption of plant protein (beyond 31 g/day) appears to enhance physical performance and reduce the risk of frailty in older individuals.Summary: Recent literature highlights numerous health benefits for older people associated with a substantial intake of plant-based vs. animal-based protein, both in preventing and mitigating chronic age-related diseases and reducing the risk of all-cause mortality. However, a high intake of plant-based protein-rich products could pose risks of malnutrition and fiber-related intestinal intolerances. Further research is needed to assess the risk-benefit ratio of a high consumption of plant proteins in older individuals before we can make robust recommendations on how far animal proteins can be healthfully replaced with plant proteins.","PeriodicalId":10962,"journal":{"name":"Current Opinion in Clinical Nutrition and Metabolic Care","volume":" ","pages":"372-377"},"PeriodicalIF":3.1,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140058902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nutrition support, carbohydrate feeding and insulin sensitivity in the critically ill patient: a complex relationship. 重症患者的营养支持、碳水化合物喂养和胰岛素敏感性：复杂的关系。

IF 3.1 3区医学

Current Opinion in Clinical Nutrition and Metabolic Care Pub Date : 2024-07-01 Epub Date: 2024-05-07 DOI: 10.1097/MCO.0000000000001039

Ra'eesa Doola, Claire Dupuis, Jean-Charles Preiser

{"title":"Nutrition support, carbohydrate feeding and insulin sensitivity in the critically ill patient: a complex relationship.","authors":"Ra'eesa Doola, Claire Dupuis, Jean-Charles Preiser","doi":"10.1097/MCO.0000000000001039","DOIUrl":"10.1097/MCO.0000000000001039","url":null,"abstract":"Purpose of review: This review aims to summarize recent studies that highlight the complex relationship between nutrition, carbohydrate, insulin provision and glycaemic control in the critically ill patient population.Recent findings: Results of observational studies concur to support early hypoglycaemia and persisting hyperglycaemia as life-threatening events. In contrast, interventional studies indicate that early macronutrient restriction appears to reduce the benefits related to insulin therapy. This restriction is however associated with improved outcomes in itself. The potential role of modified enteral solutions as an adjunctive treatment to attenuate hyperglycaemia warrants further research. The selection of a therapeutic modality may also differ according to the characteristics of the setting, such as the nurse-to-patient ratio, the type and accuracy of meters, including near-continuous glucose monitoring and the availability of computer-guided protocols.Summary: There appears to be significant interplay between nutrition, including carbohydrate provision, blood glucose control and clinical outcomes. Individualized care is probably needed to define the optimal glucose target and nutritional intervention. This can differ according to the preexistence of chronic hyperglycaemia, the timing from the onset of critical illness and the clinical condition itself.","PeriodicalId":10962,"journal":{"name":"Current Opinion in Clinical Nutrition and Metabolic Care","volume":" ","pages":"350-354"},"PeriodicalIF":3.1,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140847239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The impact of slowly digestible and resistant starch on glucose homeostasis and insulin resistance. 慢消化淀粉和抗性淀粉对葡萄糖稳态和胰岛素抵抗的影响

IF 3.1 3区医学

Current Opinion in Clinical Nutrition and Metabolic Care Pub Date : 2024-07-01 Epub Date: 2024-06-06 DOI: 10.1097/MCO.0000000000001044

Maëliss Chisbert, Anne-Laure Castell, Sophie Vinoy, Julie-Anne Nazare

{"title":"The impact of slowly digestible and resistant starch on glucose homeostasis and insulin resistance.","authors":"Maëliss Chisbert, Anne-Laure Castell, Sophie Vinoy, Julie-Anne Nazare","doi":"10.1097/MCO.0000000000001044","DOIUrl":"10.1097/MCO.0000000000001044","url":null,"abstract":"Purpose of review: This review will summarize recent studies assessing the effect of slowly digestible starch (SDS) and resistant starch (RS) on glucose metabolism in healthy, prediabetic or type 2 diabetic adults.Recent findings: Currently, a particular interest in starch and its digestibility has arisen, with data showing a positive effect of SDS and RS on the glucose homeostasis of healthy, at-risk, prediabetic and type 2 diabetic patients but research is ongoing.Summary: Carbohydrates (CHO) and especially starch play a major role in the prevention and management of metabolic diseases such as type 2 diabetes (T2D). This largely depends on the quality and the digestibility (rate and extent) of the ingested starchy products, beyond their quantity. SDS have been poorly studied but display a beneficial effect on reducing glucose excursions in healthy and insulin-resistant subjects and a relevant potential to improve glucose control in type 2 diabetic individuals. As for RS, the results appear to be encouraging but remain heterogeneous, depending the nature of the RS and its role on microbiota modulation. Further studies are needed to confirm the present results and investigate the potential complementary beneficial effects of SDS and RS on long-term glucose homeostasis to prevent cardiometabolic diseases.","PeriodicalId":10962,"journal":{"name":"Current Opinion in Clinical Nutrition and Metabolic Care","volume":" ","pages":"338-343"},"PeriodicalIF":3.1,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11155281/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141247229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Risks and benefits of nonsugar sweeteners: conflicting evidence between observational studies and randomized controlled trials. 非糖甜味剂的风险和益处：观察研究和随机对照试验之间相互矛盾的证据。

IF 3.1 3区医学

Current Opinion in Clinical Nutrition and Metabolic Care Pub Date : 2024-07-01 Epub Date: 2024-05-20 DOI: 10.1097/MCO.0000000000001048

David Faeh

引用次数: 0

Should we provide edible insects in children's diets? 我们是否应该在儿童饮食中添加可食用昆虫？

IF 3 3区医学

Current Opinion in Clinical Nutrition and Metabolic Care Pub Date : 2024-05-01 Epub Date: 2024-03-08 DOI: 10.1097/MCO.0000000000001029

Tele Chepkoros Boit, Alida Melse-Boonstra, Kim F Michaelsen, Nanna Roos

{"title":"Should we provide edible insects in children's diets?","authors":"Tele Chepkoros Boit, Alida Melse-Boonstra, Kim F Michaelsen, Nanna Roos","doi":"10.1097/MCO.0000000000001029","DOIUrl":"10.1097/MCO.0000000000001029","url":null,"abstract":"Purpose of review: Diets low in animal-source foods or solely consisting of plant-based foods, hardly meet nutrition needs of children, exposing them to inadequate intake of essential nutrients. Thus, including edible insects in children's diets is relevant for meeting nutritional requirements, other potential health benefits, and building more sustainable food systems. Nutrition and health research on insects is novel and still limited. This review covers recently published research between April 2022 and November 2023 focusing on the relevance of including insects in children's diets.Recent findings: Insects provide protein, fat and micronutrients, and are generally nutritionally equivalent to animal-source foods. The protein and fat quality of edible insects varies depending on several factors. Insects also contain chitin which could potentially be beneficial for gut health. For insects to be considered suitable for inclusion in children's diet, they must be accepted. However, children who are unfamiliar with insects respond to them with curiosity and disgust.Summary: Insect farming can enhance their availability and consumption, potentially addressing nutrition gaps. Furthermore, transitioning from occasional to regular insect consumption requires actual exposure and integration into diets of insects. To affirm the nutrition and health potential of edible insects for children, well designed human studies are essential.","PeriodicalId":10962,"journal":{"name":"Current Opinion in Clinical Nutrition and Metabolic Care","volume":" ","pages":"275-282"},"PeriodicalIF":3.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140058903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sarcopenic obesity and the impact on bone health. 肥胖症及其对骨骼健康的影响。

IF 3 3区医学

Current Opinion in Clinical Nutrition and Metabolic Care Pub Date : 2024-05-01 Epub Date: 2024-03-19 DOI: 10.1097/MCO.0000000000001032

Silvia Migliaccio, Edoardo Mocini, Marianna Minnetti, Lorenzo Maria Donini

{"title":"Sarcopenic obesity and the impact on bone health.","authors":"Silvia Migliaccio, Edoardo Mocini, Marianna Minnetti, Lorenzo Maria Donini","doi":"10.1097/MCO.0000000000001032","DOIUrl":"10.1097/MCO.0000000000001032","url":null,"abstract":"Purpose of review: Sarcopenic obesity is a newly identified pathological entity defined by an increase in body fat mass with an associated sarcopenia, characterized by loss of muscle mass, strength, and function. Recently, the concomitant presence of skeletal alteration with sarcopenic obesity has been described leading to a new clinical entity defined osteosarcopenic obesity (OSO). Many studies have tried to unravel the metabolic complex mechanism leading to this clinical entity in order to understand the pathophysiology of this complex condition with the aim of posing an early diagnosis to improve the therapeutic approaches. The purpose of this narrative review is to highlight and revise recent studies on this issue.Recent findings: Recent research in the field of OSO has highlighted the role of nutrition and physical activity in the development and management of these conditions. While molecular and cellular pathways remain partially understood, there is a growing focus on lifestyle interventions as key factors in reducing the impact of OSO. These studies emphasize the need for early diagnosis and appropriate therapeutic strategies to improve quality of life and decrease morbidity and mortality associated with OSO.Summary: Although the pathophysiological pathways underlying OSO are not fully understood, the clinical implications underscore the need for expanded research in this field. This research is crucial for enabling early diagnosis and implementing effective therapeutic interventions, with the goal of reducing morbidity and mortality and enhancing quality of life.","PeriodicalId":10962,"journal":{"name":"Current Opinion in Clinical Nutrition and Metabolic Care","volume":" ","pages":"252-255"},"PeriodicalIF":3.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140317956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0