Current Opinion in Clinical Nutrition and Metabolic Care最新文献_第10页

Assessing systemic inflammation and its prognostic value: Glasgow Prognostic Score, neutrophil-to-lymphocyte ratio or other options? 评估全身性炎症及其预后价值：格拉斯哥预后评分、中性粒细胞与淋巴细胞比率还是其他选择？

IF 3.5 3区医学

Current Opinion in Clinical Nutrition and Metabolic Care Pub Date : 2025-09-01 Epub Date: 2025-08-01 DOI: 10.1097/MCO.0000000000001151

Maurizio Muscaritoli, Alessio Molfino, Simona Orlando, Federica Tambaro

{"title":"Assessing systemic inflammation and its prognostic value: Glasgow Prognostic Score, neutrophil-to-lymphocyte ratio or other options?","authors":"Maurizio Muscaritoli, Alessio Molfino, Simona Orlando, Federica Tambaro","doi":"10.1097/MCO.0000000000001151","DOIUrl":"https://doi.org/10.1097/MCO.0000000000001151","url":null,"abstract":"Purpose of review: Systemic inflammation represents a complex, widespread physiological response initiated by the body in response to various noxious stressors, including infections, trauma, surgery, and chronic diseases. The assessment of systemic inflammation relies on a spectrum of measurable biological indicators.This review evaluates the current evidence on several systemic inflammation biomarkers, including the traditional Glasgow Prognostic Score (GPS) and other emerging indices such as the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), lymphocyte-to-monocyte ratio (LMR), systemic immune-inflammation index (SII), and systemic inflammation response index (SIRI).Recent findings: Several simple biomarkers can assess systemic inflammation, each with specific strengths and limitations. The GPS is a well validated index in oncology and is increasingly being used in cardiovascular disease, integrating inflammatory and nutritional status. Blood count-derived ratios such as NLR, PLR, LMR, SII, and SIRI are widely available and have shown prognostic value across different clinical conditions. Current evidence supports their use in risk stratification and clinical decision-making, though interpretation should always consider the overall clinical picture.Summary: Inflammation biomarkers like GPS, NLR, PLR, LMR, SII, and SIRI offer accessible tools for risk stratification, with clinical utility varying by context and requiring further standardization.","PeriodicalId":10962,"journal":{"name":"Current Opinion in Clinical Nutrition and Metabolic Care","volume":"28 5","pages":"367-372"},"PeriodicalIF":3.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144793667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bioelectrical impedance analysis instruments: how do they differ, what do we need for clinical assessment? 生物电阻抗分析仪器：它们有何不同，临床评估需要什么？

IF 3.5 3区医学

Current Opinion in Clinical Nutrition and Metabolic Care Pub Date : 2025-09-01 Epub Date: 2025-07-15 DOI: 10.1097/MCO.0000000000001142

Yves M Dupertuis, Wedali Jimaja, Cheryle Beardsley Levoy, Laurence Genton

{"title":"Bioelectrical impedance analysis instruments: how do they differ, what do we need for clinical assessment?","authors":"Yves M Dupertuis, Wedali Jimaja, Cheryle Beardsley Levoy, Laurence Genton","doi":"10.1097/MCO.0000000000001142","DOIUrl":"10.1097/MCO.0000000000001142","url":null,"abstract":"Purpose of review: Bioelectrical impedance analysis (BIA) is a widely used, noninvasive method for assessing body composition. Recent technological advances have diversified BIA devices in terms of measurement frequency, electrode configuration, and portability. This review outlines key criteria for selecting a BIA system according to clinical or research needs.Recent findings: Single-frequency BIA (SF-BIA) devices, typically consumer-grade with hand-to-hand or foot-to-foot configurations, are affordable and easy to use but often lack raw data access, clinical validation, and regulatory certification. In contrast, multifrequency BIA (MF-BIA) systems, especially octopolar models, enable segmental analysis and provide greater accuracy for evaluating fluid distribution and lean mass. However, they are costlier, depend on proprietary algorithms, and generally require standing measurements. In hospital settings, portable MF-BIA devices that allow supine, tetrapolar or octopolar assessments are preferable, particularly for use with bedridden patients. Across all contexts, standardized measurement protocols and access to raw parameters ( Z , R , Xc, PhA) are essential to apply accurate, population-specific predictive equations.Summary: Reliable use of BIA requires careful consideration of device type, data accessibility, and methodological consistency. Portable, regulatory-certified MF-BIA systems with tetrapolar or octopolar configurations and access to raw data offer the most accurate and adaptable solutions for clinical and research applications.","PeriodicalId":10962,"journal":{"name":"Current Opinion in Clinical Nutrition and Metabolic Care","volume":" ","pages":"379-387"},"PeriodicalIF":3.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12337901/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Editorial: Detecting and assessing malnutrition: emerging principles and practice. 社论：检测和评估营养不良：新出现的原则和实践。

IF 3.8 3区医学

Current Opinion in Clinical Nutrition and Metabolic Care Pub Date : 2025-09-01 Epub Date: 2025-08-07 DOI: 10.1097/MCO.0000000000001152

Jann Arends, Kianoush B Kashani

引用次数: 0

The sick gut with diarrhea: FODMAPS for treatment? 腹泻的肠道疾病：FODMAPS治疗？

IF 3.5 3区医学

Current Opinion in Clinical Nutrition and Metabolic Care Pub Date : 2025-09-01 Epub Date: 2025-07-07 DOI: 10.1097/MCO.0000000000001141

Pascal Crenn

引用次数: 0

Searching for defining adequate protein intake in ICU patients: is intention to treat analysis the best? 寻找ICU患者足够蛋白质摄入量的定义：意向治疗分析是最好的吗？

IF 3.5 3区医学

Current Opinion in Clinical Nutrition and Metabolic Care Pub Date : 2025-09-01 Epub Date: 2025-07-11 DOI: 10.1097/MCO.0000000000001145

Eric Fontaine

引用次数: 0

What is the value of anthropometry for estimating muscle mass? 人体测量法在估计肌肉质量方面的价值是什么？

IF 3.5 3区医学

Current Opinion in Clinical Nutrition and Metabolic Care Pub Date : 2025-09-01 Epub Date: 2025-07-04 DOI: 10.1097/MCO.0000000000001143

Camila Kümmel Duarte, Luciana de Abreu Silva

{"title":"What is the value of anthropometry for estimating muscle mass?","authors":"Camila Kümmel Duarte, Luciana de Abreu Silva","doi":"10.1097/MCO.0000000000001143","DOIUrl":"10.1097/MCO.0000000000001143","url":null,"abstract":"Purpose of review: Skeletal muscle mass is essential for mobility, physical performance, and disease prevention, serving as a predictor of morbidity and mortality, particularly in sarcopenia. Muscle mass decreases with age and is associated with adverse clinical outcomes. Accurate assessment is crucial in clinical practice but presents challenges.Recent findings: Imaging methods like MRI, DXA, computed tomography (CT), ultrasound, and other techniques like bioelectrical impedance analysis (BIA) are effective but have limitations such as cost, accessibility, and operator dependency. Anthropometric measures - such as calf circumference, mid-upper arm circumference (MUAC), forearm, and thigh circumference - are simple, low-cost alternatives that correlate well with muscle mass, though they can be influenced by factors like age, sex, and body fat. Adjusted measures using skinfold thickness improve accuracy but are less reliable in older adults. Prediction equations based on anthropometry can estimate total muscle mass but must be validated for specific populations. In complex cases like obesity or malnutrition, equations that incorporate biochemical markers or dynamometry may enhance precision.Summary: Overall, selecting the appropriate muscle mass assessment method requires consideration of population characteristics, available resources, and proper professional training to ensure accurate and clinically useful results.","PeriodicalId":10962,"journal":{"name":"Current Opinion in Clinical Nutrition and Metabolic Care","volume":" ","pages":"403-407"},"PeriodicalIF":3.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144625517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

How to feed patients with small intestinal dysmotility. 小肠运动障碍患者如何喂养。

IF 3.5 3区医学

Current Opinion in Clinical Nutrition and Metabolic Care Pub Date : 2025-09-01 Epub Date: 2025-06-23 DOI: 10.1097/MCO.0000000000001139

Thomas Edward Conley, Emily Creed, Simon Lal

{"title":"How to feed patients with small intestinal dysmotility.","authors":"Thomas Edward Conley, Emily Creed, Simon Lal","doi":"10.1097/MCO.0000000000001139","DOIUrl":"10.1097/MCO.0000000000001139","url":null,"abstract":"Purpose of review: Chronic small intestinal dysmotility is associated with a spectrum of malnutrition, varying in severity from mild nutritional compromise to intestinal failure requiring parenteral nutrition. Feeding patients with chronic small intestinal dysmotility is one of the most complex challenges in contemporary clinical gastroenterology. This review is timely due to rising diagnostic uncertainty reflected in increasing referrals for parenteral nutrition, and the growing awareness of overlapping high symptom burden but non-intestinal failure inducing disorders.Recent findings: Whilst the pragmatic classification into chronic intestinal pseudo-obstruction (CIPO) and non-CIPO subtypes may help avoid unnecessary invasive investigations and provides insight into nutritional trajectory, this evolving approach requires careful navigation of the emerging diagnostic grey zone that encompasses highly symptomatic disorders of gut-brain interaction, disordered eating, and opioid-related bowel dysfunction that can result in pain/intolerance on small intestinal feeding. Feeding strategies must be tailored to phenotype and symptom burden, with enteral support prioritised wherever possible and parenteral nutrition reserved for clear cases of intestinal failure and/or for a temporising period of time when there is life-threatening nutritional risk. Effective management depends on early multidisciplinary input, optimisation of pharmacotherapy, and psychological assessment to guide appropriate nutritional therapies.Summary: Individualised feeding strategies must weigh the risks of malnutrition against those associated with parenteral support, while also addressing symptom severity and maintaining oversight of the broader psychosocial context. This review reinforces the importance of early multidisciplinary team engagement, considered therapeutic approaches, and nuanced clinical reasoning in managing patients with chronic small intestinal dysmotility.","PeriodicalId":10962,"journal":{"name":"Current Opinion in Clinical Nutrition and Metabolic Care","volume":" ","pages":"427-432"},"PeriodicalIF":3.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144526776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nutrition in inflammatory bowel disease: new trends. 炎症性肠病的营养：新趋势。

IF 3.5 3区医学

Current Opinion in Clinical Nutrition and Metabolic Care Pub Date : 2025-09-01 Epub Date: 2025-07-07 DOI: 10.1097/MCO.0000000000001140

Nathan Kuk, Chu K Yao, Ashish R Srinivasan, Abhinav Vasudevan

{"title":"Nutrition in inflammatory bowel disease: new trends.","authors":"Nathan Kuk, Chu K Yao, Ashish R Srinivasan, Abhinav Vasudevan","doi":"10.1097/MCO.0000000000001140","DOIUrl":"10.1097/MCO.0000000000001140","url":null,"abstract":"Purpose of review: This review examines the latest evidence and highlights the importance of personalized dietary therapies to augment conventional medical treatments in the treatment of inflammatory bowel disease.Recent findings: Diversity in the maternal diet may reduce the risk of development of ulcerative colitis in utero, while a diverse diet during childhood may reduce the risk of future inflammatory bowel disease. During adulthood, the Mediterranean diet (MED) and Diet A Stop Hypertension may reduce the risk of developing inflammatory bowel disease, with some evidence to support that anthocyanin intake is a beneficial component of the diet. For dietary therapy for the maintenance of remission in Crohn's disease, it appears that the MED and simple carbohydrate diet and variations of this diet may be beneficial, although more trials are needed to confirm this.Summary: the role of diet in preventing inflammatory bowel disease and treating symptoms continues to evolve and dietary changes may be considered in addition to medical therapy in the treatment of inflammatory bowel disease.","PeriodicalId":10962,"journal":{"name":"Current Opinion in Clinical Nutrition and Metabolic Care","volume":" ","pages":"410-421"},"PeriodicalIF":3.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144625514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Key considerations for who, when, why, and how to screen for malnutrition. 谁、何时、为何以及如何筛查营养不良的关键考虑因素。

IF 3.5 3区医学

Current Opinion in Clinical Nutrition and Metabolic Care Pub Date : 2025-09-01 Epub Date: 2025-07-07 DOI: 10.1097/MCO.0000000000001144

Ingvild Paur, Inger Ottestad

{"title":"Key considerations for who, when, why, and how to screen for malnutrition.","authors":"Ingvild Paur, Inger Ottestad","doi":"10.1097/MCO.0000000000001144","DOIUrl":"10.1097/MCO.0000000000001144","url":null,"abstract":"Purpose of review: Confusion and disagreement about malnutrition screening, how, when, why, who to screen, and which screening tool to use, have persisted since the Global Leadership Initiative on Malnutrition (GLIM) established the malnutrition diagnosis in 2019. In this review, we discuss the purpose of malnutrition screening, presents recent validations of screening tools and how the choice of tools affects malnutrition prevalence within the GLIM framework.Recent findings: The screening for malnutrition should consider the results of recent validations of screening tools against the GLIM criteria, which reveal variations based on the specific tool, the population, and the setting. Likewise, the prevalence of malnutrition varies with the population and setting, and even how screening tools are applied in the process. Currently, all screening tools exclude patients who meet the GLIM criteria for a malnutrition diagnosis, but the extent of exclusion varies.Summary: In this review, we summarize recent prevalence and validation studies on screening tools related to GLIM. We argue that screening tools should align with GLIM malnutrition diagnosis criteria, need to be validated against GLIM, and discuss the requirement that a positive screening result is mandatory for a malnutrition diagnosis.","PeriodicalId":10962,"journal":{"name":"Current Opinion in Clinical Nutrition and Metabolic Care","volume":" ","pages":"388-395"},"PeriodicalIF":3.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144625513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessing body composition and energy expenditure in ICU. 评估ICU患者的身体成分和能量消耗。

IF 3.5 3区医学

Current Opinion in Clinical Nutrition and Metabolic Care Pub Date : 2025-09-01 Epub Date: 2025-07-11 DOI: 10.1097/MCO.0000000000001146

Pierre Singer, Michal Slevin Kish

{"title":"Assessing body composition and energy expenditure in ICU.","authors":"Pierre Singer, Michal Slevin Kish","doi":"10.1097/MCO.0000000000001146","DOIUrl":"10.1097/MCO.0000000000001146","url":null,"abstract":"Purpose of review: The \"One Size fits All\" nutritional approach, mainly using the patient's weight, has been challenged by recent progress allowing healthcare professionals to better define energy needs and determine body composition.Recent findings: The Global Leadership Initiative on Malnutrition (GLIM) assessment has been recognized as a reliable tool for diagnosing malnutrition in the ICU. Complementing this approach, advancements in techniques for evaluating lean muscle mass, such as dual-energy biomarkers and computed tomography (CT), have improved the accuracy of muscle mass determination. When conducted by experienced practitioners, ultrasound offers a fast, reliable, and reproducible method for assessing muscle mass. Additionally, bioelectrical impedance analysis (BIA) has benefited from technological and methodological improvements, allowing the use of body cell mass as a guide for protein administration. Energy expenditure is most accurately measured using indirect calorimetry, which should be performed regularly due to day-to-day fluctuations and prevent the risks of overfeeding or underfeeding.Summary: All these progresses are paving the way to precision nutrition in intensive care, determining more accurately the energy needs and adapting the macronutrient administration according to body composition and not anymore by kilogram weight.","PeriodicalId":10962,"journal":{"name":"Current Opinion in Clinical Nutrition and Metabolic Care","volume":" ","pages":"396-402"},"PeriodicalIF":3.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144625511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0