Current Opinion in Clinical Nutrition and Metabolic Care最新文献_第10页

Evidence on docosahexaenoic acid and arachidonic acid supplementation for preterm infants. 早产儿补充二十二碳六烯酸和花生四烯酸的证据。

IF 3 3区医学

Current Opinion in Clinical Nutrition and Metabolic Care Pub Date : 2024-05-01 Epub Date: 2024-03-15 DOI: 10.1097/MCO.0000000000001035

Alexandre Lapillonne, Chiara Lembo, Sissel J Moltu

{"title":"Evidence on docosahexaenoic acid and arachidonic acid supplementation for preterm infants.","authors":"Alexandre Lapillonne, Chiara Lembo, Sissel J Moltu","doi":"10.1097/MCO.0000000000001035","DOIUrl":"10.1097/MCO.0000000000001035","url":null,"abstract":"Purpose of review: For many decades, docosahexaenoic acid (DHA) supplementation was tested in premature infants to achieve an intake equivalent to the average level in breast milk, but this approach has led to conflicting results in terms of development and health outcomes. Higher doses of DHA closer to fetal accumulation may be needed.Recent findings: The efficacy of DHA supplementation for preterm infants at a dose equivalent to the estimated fetal accumulation rate is still under investigation, but this may be a promising approach, especially in conjunction with arachidonic acid supplementation. Current data suggest benefit for some outcomes, such as brain maturation, long-term cognitive function, and the prevention of retinopathy of prematurity. The possibility that supplementation with highly unsaturated oils increases the risk of neonatal morbidities should not be ruled out, but current meta-analyzes do not support a significant risk.Summary: The published literature supports a DHA intake in preterm infants that is closer to the fetal accumulation rate than the average breast milk content. Supplementation with DHA at this level in combination with arachidonic acid is currently being investigated and appears promising.","PeriodicalId":10962,"journal":{"name":"Current Opinion in Clinical Nutrition and Metabolic Care","volume":" ","pages":"283-289"},"PeriodicalIF":3.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140317954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Editorial introductions.

IF 3 3区医学

Current Opinion in Clinical Nutrition and Metabolic Care Pub Date : 2024-05-01 Epub Date: 2024-04-04 DOI: 10.1097/MCO.0000000000001031

引用次数: 0

Beyond the reproductive tract: gut microbiome and its influence on gynecological health. 超越生殖道：肠道微生物群及其对妇科健康的影响。

IF 3.1 3区医学

Current Opinion in Clinical Nutrition and Metabolic Care Pub Date : 2024-04-09 DOI: 10.1097/gco.0000000000000952

Inmaculada Pérez-Prieto, Aida Rodríguez-Santisteban, Signe Altmäe

引用次数: 0

Beyond the reproductive tract: gut microbiome and its influence on gynecological health. 超越生殖道：肠道微生物群及其对妇科健康的影响。

IF 3.1 3区医学

Current Opinion in Clinical Nutrition and Metabolic Care Pub Date : 2024-04-08 DOI: 10.1097/01.gco.0001016536.06312.72

Inmaculada Pérez-Prieto, Aida Rodríguez-Santisteban, Signe Altmäe

引用次数: 0

Editorial: Quantitative and qualitative aspects of lipids and lipoproteins in health and disease: nutrition, physiology and genetics. 社论：脂质和脂蛋白在健康和疾病中的定量和定性方面：营养学、生理学和遗传学。

IF 3.1 3区医学

Current Opinion in Clinical Nutrition and Metabolic Care Pub Date : 2024-03-01 Epub Date: 2024-02-08 DOI: 10.1097/MCO.0000000000001015

Philip C Calder, Gerald F Watts

引用次数: 0

Editorial: The interaction between protein delivery and blood urea and ammonia during critical illness. 社论：危重病期间蛋白质输送与血尿素和血氨之间的相互作用。

IF 3 3区医学

Current Opinion in Clinical Nutrition and Metabolic Care Pub Date : 2024-03-01 Epub Date: 2024-02-08 DOI: 10.1097/MCO.0000000000001016

Adam M Deane, Michael P Casaer

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Long-chain n -3 polyunsaturated fatty acids for the management of age- and disease-related declines in skeletal muscle mass, strength and physical function. 长链n-3多不饱和脂肪酸用于治疗与年龄和疾病相关的骨骼肌质量、力量和身体功能下降。

IF 3.1 3区医学

Current Opinion in Clinical Nutrition and Metabolic Care Pub Date : 2024-03-01 Epub Date: 2023-10-17 DOI: 10.1097/MCO.0000000000000986

Nathan Phillips, Stuart R Gray, Emilie Combet, Oliver C Witard

{"title":"Long-chain n -3 polyunsaturated fatty acids for the management of age- and disease-related declines in skeletal muscle mass, strength and physical function.","authors":"Nathan Phillips, Stuart R Gray, Emilie Combet, Oliver C Witard","doi":"10.1097/MCO.0000000000000986","DOIUrl":"10.1097/MCO.0000000000000986","url":null,"abstract":"Purpose of review: This review uses the hierarchy of evidence as a framework to critically evaluate the effect of long chain n -3 polyunsaturated fatty acid (LC n -3 PUFA) ingestion alone, or as an adjunctive intervention to resistance training, on muscle health-related outcomes in healthy and clinical older adult populations.Recent findings: Systematic reviews and meta-analyses of randomized controlled trials consistently report small, but clinically-relevant, effects of LC n -3 PUFA ingestion on strength outcomes, whereas mixed findings have been reported regarding changes in muscle mass and physical function. Cohort studies indicate an association between higher dietary LC n -3 PUFA intake and reduced likelihood of a sarcopenia diagnosis. Acute metabolic studies provide limited evidence for an effect of LC n -3 PUFA ingestion alone, or in combination with resistance training, on free-living integrated rates of MPS, static markers of muscle protein breakdown, or satellite cell activation in healthy older adults.Summary: Recent data supports the efficacy of LCn-3 PUFA ingestion to facilitate small, but clinically relevant, improvements in muscle strength in healthy and clinical older adult populations. The mechanism(s) that underpin the action of LC n -3 PUFA in promoting strength outcomes remain unknown, but likely relate to neuromuscular function.","PeriodicalId":10962,"journal":{"name":"Current Opinion in Clinical Nutrition and Metabolic Care","volume":" ","pages":"98-105"},"PeriodicalIF":3.1,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49689195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Metabolic management of accidental intoxication. 意外中毒的代谢处理。

IF 3.1 3区医学

Current Opinion in Clinical Nutrition and Metabolic Care Pub Date : 2024-03-01 Epub Date: 2024-01-17 DOI: 10.1097/MCO.0000000000001013

Khalid Khatib, Subhal Dixit, Madhavi Telang

{"title":"Metabolic management of accidental intoxication.","authors":"Khalid Khatib, Subhal Dixit, Madhavi Telang","doi":"10.1097/MCO.0000000000001013","DOIUrl":"10.1097/MCO.0000000000001013","url":null,"abstract":"Purpose of review: Unintentional intoxication comprises a major chunk of all intoxications. Most patients are in the pediatric age group with another set of patients being the elderly. Substances found to cause accidental intoxication vary from country to country and even within different regions of a country. Frequent reviews of current literature are needed to be abreast of trends.Recent findings: Prescription drugs and household chemicals are major culprits when it comes to accidental intoxication. Acetaminophen, digoxin and metformin are some of the prominent prescription drugs frequently associated with unintentional intoxications. Increasingly alcohol based hand sanitizers are becoming an important etiology of these events, following their increased usage during the COVID-19 pandemic. Pattern recognition to identify class of intoxicant and supportive care including prevention of further absorption and increased excretion are cornerstones of therapy. Antidote when available should be used promptly.Summary: Knowledge about current epidemiology of accidental intoxications, toxidrome pattern recognition and appropriate antidote usage beside adequate and timely supportive care help in successful management of the unfortunate victim of accidental intoxication.","PeriodicalId":10962,"journal":{"name":"Current Opinion in Clinical Nutrition and Metabolic Care","volume":" ","pages":"147-154"},"PeriodicalIF":3.1,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139520357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Can the gut microbiome inform the effects of omega-3 fatty acid supplementation trials on cognition? 肠道微生物组能否为欧米伽-3 脂肪酸补充试验对认知的影响提供信息？

IF 3 3区医学

Current Opinion in Clinical Nutrition and Metabolic Care Pub Date : 2024-03-01 Epub Date: 2023-12-22 DOI: 10.1097/MCO.0000000000001007

Bilal E Kerman, Wade Self, Hussein N Yassine

{"title":"Can the gut microbiome inform the effects of omega-3 fatty acid supplementation trials on cognition?","authors":"Bilal E Kerman, Wade Self, Hussein N Yassine","doi":"10.1097/MCO.0000000000001007","DOIUrl":"10.1097/MCO.0000000000001007","url":null,"abstract":"Purpose of review: Most omega-3 polyunsaturated fatty acid (n-3 PUFA) supplementation clinical trials report inconsistent or null findings on measures of cognition or Alzheimer's disease (AD) with a relatively large variability in the response to n-3 PUFA supplementation. The purpose of this review is to identify whether the gut microbiome together with the metabolome can provide critical insights to understand this heterogeneity in the response to n-3 PUFA supplementation.Recent findings: A Western diet with high saturated fat and omega-6 fatty acid content, obesity, and lack of exercise puts strain on the gut microbiome resulting in imbalance, dysbiosis, reduced bacterial diversity, and increased abundance of the pro-inflammatory taxa. A plant-based diet has beneficial effects on the gut microbiota even when deficient in n-3 PUFAs. Human and animal studies show that increased intake of the n-3 PUFAs correlates with increased beneficial intestinal bacteria when compared to a Western diet.Summary: The composition of the gut microbiota can help define the effects of n-3 PUFA supplementation on the brain and lead to more personalized nutritional interventions.","PeriodicalId":10962,"journal":{"name":"Current Opinion in Clinical Nutrition and Metabolic Care","volume":" ","pages":"116-124"},"PeriodicalIF":3.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10872319/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139086219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The future of artificial intelligence in clinical nutrition. 人工智能在临床营养学中的未来。

IF 3.1 3区医学

Current Opinion in Clinical Nutrition and Metabolic Care Pub Date : 2024-03-01 Epub Date: 2023-08-29 DOI: 10.1097/MCO.0000000000000977

Pierre Singer, Eyal Robinson, Orit Raphaeli

{"title":"The future of artificial intelligence in clinical nutrition.","authors":"Pierre Singer, Eyal Robinson, Orit Raphaeli","doi":"10.1097/MCO.0000000000000977","DOIUrl":"10.1097/MCO.0000000000000977","url":null,"abstract":"Purpose of review: Artificial intelligence has reached the clinical nutrition field. To perform personalized medicine, numerous tools can be used. In this review, we describe how the physician can utilize the growing healthcare databases to develop deep learning and machine learning algorithms, thus helping to improve screening, assessment, prediction of clinical events and outcomes related to clinical nutrition.Recent findings: Artificial intelligence can be applied to all the fields of clinical nutrition. Improving screening tools, identifying malnourished cancer patients or obesity using large databases has been achieved. In intensive care, machine learning has been able to predict enteral feeding intolerance, diarrhea, or refeeding hypophosphatemia. The outcome of patients with cancer can also be improved. Microbiota and metabolomics profiles are better integrated with the clinical condition using machine learning. However, ethical considerations and limitations of the use of artificial intelligence should be considered.Summary: Artificial intelligence is here to support the decision-making process of health professionals. Knowing not only its limitations but also its power will allow precision medicine in clinical nutrition as well as in the rest of the medical practice.","PeriodicalId":10962,"journal":{"name":"Current Opinion in Clinical Nutrition and Metabolic Care","volume":" ","pages":"200-206"},"PeriodicalIF":3.1,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10178007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0