Current Opinion in Clinical Nutrition and Metabolic Care最新文献_第9页

Micronutrient (iron, selenium, vitamin D) supplementation and the gut microbiome. 微量营养素（铁、硒、维生素 D）补充剂与肠道微生物群。

IF 3 3区医学

Current Opinion in Clinical Nutrition and Metabolic Care Pub Date : 2024-09-01 Epub Date: 2024-05-21 DOI: 10.1097/MCO.0000000000001046

Amelia Faradina, Alexey A Tinkov, Anatoly V Skalny, Jung-Su Chang

{"title":"Micronutrient (iron, selenium, vitamin D) supplementation and the gut microbiome.","authors":"Amelia Faradina, Alexey A Tinkov, Anatoly V Skalny, Jung-Su Chang","doi":"10.1097/MCO.0000000000001046","DOIUrl":"10.1097/MCO.0000000000001046","url":null,"abstract":"Purpose of review: Deficiencies in micronutrients persist as widespread global challenges, where supplementation remains a crucial therapeutic approach. This review aims to elucidate the intricate relationships between micronutrient supplementation - specifically iron, selenium (Se), and vitamin D (Vit D) - and gut microbiota composition, investigating their collective impact on host health and disease susceptibility.Recent findings: Maintaining balanced iron levels is essential for gut microbiota equilibrium and host health, as both iron deficiency and excess disrupt gut bacterial balance, affecting colon health. Se supplementation can restore and improve the gut microbial balance, influencing health outcomes not only in the gut but also in areas such as neuroprotection in the brain, testicular health, and metabolic syndrome. Clinical and experimental models demonstrate that Vit D modulates the gut microbiome, enhancing anti-inflammatory effects, supporting metabolic health, and potentially reducing the risk of gut-related behavioral changes and diseases.Summary: Findings of this review emphasize that balanced iron levels are essential for maintaining a healthy gut microbiota composition and underscore the beneficial effects of Se and Vit D in modulating the gut microbiome. The interactions between micronutrients and the gut microbiome are complex but may have a broad spectrum of health outcomes.","PeriodicalId":10962,"journal":{"name":"Current Opinion in Clinical Nutrition and Metabolic Care","volume":" ","pages":"421-427"},"PeriodicalIF":3.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141247126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Global Leadership Initiative on Malnutrition cachexia: an inflammation-first approach for the diagnosis of disease-related malnutrition. 营养不良恶病质全球领导倡议：诊断疾病相关营养不良的炎症优先方法。

IF 3 3区医学

Current Opinion in Clinical Nutrition and Metabolic Care Pub Date : 2024-09-01 Epub Date: 2024-08-08 DOI: 10.1097/MCO.0000000000001052

Josh McGovern, Richard J E Skipworth, Barry J A Laird, Donald C McMillan

{"title":"Global Leadership Initiative on Malnutrition cachexia: an inflammation-first approach for the diagnosis of disease-related malnutrition.","authors":"Josh McGovern, Richard J E Skipworth, Barry J A Laird, Donald C McMillan","doi":"10.1097/MCO.0000000000001052","DOIUrl":"https://doi.org/10.1097/MCO.0000000000001052","url":null,"abstract":"Purpose of review: The following article examines the rationale for an inflammation-first approach for diagnosing cachexia and how the current Global Leadership Initiative on Malnutrition (GLIM) framework may be adapted to facilitate this.Recent findings: Recently, the GLIM have published guidance on the measurement of inflammation in the context of cachexia, advocating that C-reactive protein (CRP) should be utilized for quantification. The inclusion of a systemic inflammatory biomarker for the diagnosis of cachexia questions whether it may be more aptly considered a systemic inflammatory syndrome.Summary: The current consensus of the GLIM is that cachexia is 'disease-related malnutrition with inflammation'. In line with this definition, the GLIM proposed a two-step diagnostic framework: screening for malnutrition using validated screening tools and then confirming the presence of disease-related malnutrition with phenotypic (nonvolitional weight loss, low BMI, and reduced muscle mass) and aetiologic criterion reduced food intake/assimilation, and inflammation or disease burden). The GLIM are to be commended for guidance on the measurement of systemic inflammation in their current proposal, given the relative importance to clinical outcomes in patients with cancer. However, the use of CRP is somewhat rudimentary and contrasts other cancer cachexia guidelines and contemporary clinical cancer research.","PeriodicalId":10962,"journal":{"name":"Current Opinion in Clinical Nutrition and Metabolic Care","volume":"27 5","pages":"393-396"},"PeriodicalIF":3.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141897038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of dietary fibres in cardiometabolic diseases. 膳食纤维在心脏代谢疾病中的作用。

IF 3.1 3区医学

Current Opinion in Clinical Nutrition and Metabolic Care Pub Date : 2024-07-01 Epub Date: 2024-05-16 DOI: 10.1097/MCO.0000000000001047

Christina C Dahm, Fie Langmann, Anne Østergaard Nannsen, Daniel B Ibsen

{"title":"Role of dietary fibres in cardiometabolic diseases.","authors":"Christina C Dahm, Fie Langmann, Anne Østergaard Nannsen, Daniel B Ibsen","doi":"10.1097/MCO.0000000000001047","DOIUrl":"10.1097/MCO.0000000000001047","url":null,"abstract":"Purpose of review: This review highlights recent developments in understanding the role of dietary fibre and specific fibre types on risk and management of cardiometabolic disease with a focus on the causal pathways leading to cardiometabolic diseases, namely weight management, glycaemic control, and lipid levels, as well as the latest findings for cardiovascular disease outcomes such as coronary heart disease, stroke, and mortality. Evidence for mechanisms through gut microbiota are also briefly reviewed.Recent findings: Dietary fibre intake is associated with improved weight management, the extent of which may depend on the subtype of dietary fibre. Overall dietary fibre intake reduces blood glucose and HbA1c, however soluble fibres may be particularly effective in reducing HbA1c, fasting blood glucose and blood lipids. Individual meta-analyses and umbrella reviews of observational studies on dietary fibre, as well as major fibre types, observed inverse associations with incident coronary heart disease, stroke, and mortality due to cardiovascular disease. As different types of fibres exerted different health benefits, fibre diversity (i.e. combinations of fibres) should be further investigated.Summary: Dietary fibres improve both short-term and long-term cardiometabolic disease risk factors and outcomes, and thus should be on every menu.","PeriodicalId":10962,"journal":{"name":"Current Opinion in Clinical Nutrition and Metabolic Care","volume":" ","pages":"355-360"},"PeriodicalIF":3.1,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141247220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Editorial: unravelling the trifecta: obesity, cancer, and DNA damage. 社论：揭开肥胖、癌症和 DNA 损伤三部曲的神秘面纱。

IF 3 3区医学

Current Opinion in Clinical Nutrition and Metabolic Care Pub Date : 2024-07-01 Epub Date: 2024-06-06 DOI: 10.1097/MCO.0000000000001040

Anastasia Z Kalea, Dorothy Klimis-Zacas

引用次数: 0

Lactose malabsorption and intolerance in older adults. 老年人乳糖吸收不良和不耐受。

IF 3.1 3区医学

Current Opinion in Clinical Nutrition and Metabolic Care Pub Date : 2024-07-01 Epub Date: 2024-06-06 DOI: 10.1097/MCO.0000000000001045

Antonella Gallo, Emanuele Marzetti, Simona Pellegrino, Massimo Montalto

{"title":"Lactose malabsorption and intolerance in older adults.","authors":"Antonella Gallo, Emanuele Marzetti, Simona Pellegrino, Massimo Montalto","doi":"10.1097/MCO.0000000000001045","DOIUrl":"10.1097/MCO.0000000000001045","url":null,"abstract":"Purpose of review: Lactose malabsorption and intolerance are very common conditions. However, their optimal approach, including the diagnostic assessment, remains a matter of debate, especially in advanced age. In this brief review, we focused on current knowledge, concerns, and impact in clinical practice of lactose malabsorption and intolerance in elderly.Recent findings: Older adults are at high risk of malnutrition, owing to frequent occurrence of cognitive impairment, loss of appetite, dysphagia, and poor oral health. A significant decrease in the consumption of dairy products may lead to inadequate intake of high-quality protein and minerals, with a consequent impact on muscle and bone health. Testing for lactose malabsorption may be challenging in older adults, if not useless. Instead, a detailed clinical evaluation should always be pursued to identify both lactose intolerance and all confounding factors mimicking the same clinical picture.Summary: The management of lactose malabsorption and intolerance in older adults deserves a personalized approach. Because of the importance of maintaining an adequate nutritional status in this age group, efforts should be put forth to avoid excessively restrictive diets.","PeriodicalId":10962,"journal":{"name":"Current Opinion in Clinical Nutrition and Metabolic Care","volume":" ","pages":"333-337"},"PeriodicalIF":3.1,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11155274/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141247121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Carbohydrates in the context of metabolic diseases. 代谢性疾病中的碳水化合物。

IF 3.1 3区医学

Current Opinion in Clinical Nutrition and Metabolic Care Pub Date : 2024-07-01 Epub Date: 2024-06-06 DOI: 10.1097/MCO.0000000000001041

Lia Bally, Leonidas G Karagounis

引用次数: 0

Nourishing the gut: the impact of diet on host-gut microbiota interaction. 滋养肠道：饮食对宿主-肠道微生物群相互作用的影响。

IF 3.1 3区医学

Current Opinion in Clinical Nutrition and Metabolic Care Pub Date : 2024-07-01 Epub Date: 2024-01-17 DOI: 10.1097/MCO.0000000000001009

Davide Masi, Tiphaine Le Roy, Solia Adriouch, Karine Clément

{"title":"Nourishing the gut: the impact of diet on host-gut microbiota interaction.","authors":"Davide Masi, Tiphaine Le Roy, Solia Adriouch, Karine Clément","doi":"10.1097/MCO.0000000000001009","DOIUrl":"10.1097/MCO.0000000000001009","url":null,"abstract":"Purpose of review: Understanding the spectrum of drivers that influence the gut microbiome (GM) remains a crucial field of investigation. Among these factors, diet has received particular attention, as it could explain up to 20% of the variability in GM composition between individuals. This review focuses on the complex relationships between different dietary patterns and GM in humans, based on recent findings.Recent findings: Current evidence underscores the multifaceted impact of diet on GM richness, diversity, and overall composition. Key contributing factors encompass dietary habits, nutritional interventions, food quality and variety, macronutrient distribution, timing of feeding, and selective exclusion of certain foods.Summary: The intricate interplay between diet and GM is of fundamental importance in shaping the interaction between the host and the environment. Further understanding the causal impact of diet on GM has promising potential for the advancement of strategies to promote health and mitigate cardio-metabolic disease risks through dietary interventions.Graphical abstract: http://links.lww.com/COCN/A21.","PeriodicalId":10962,"journal":{"name":"Current Opinion in Clinical Nutrition and Metabolic Care","volume":" ","pages":"361-371"},"PeriodicalIF":3.1,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139520398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Plant proteins: are they a good alternative to animal proteins in older people? 植物蛋白：它们是老年人动物蛋白的良好替代品吗？

IF 3.1 3区医学

Current Opinion in Clinical Nutrition and Metabolic Care Pub Date : 2024-07-01 Epub Date: 2024-03-01 DOI: 10.1097/MCO.0000000000001026

Lina Toutirais, Carole Vaysse, Marine Gueugneau, Stephane Walrand

{"title":"Plant proteins: are they a good alternative to animal proteins in older people?","authors":"Lina Toutirais, Carole Vaysse, Marine Gueugneau, Stephane Walrand","doi":"10.1097/MCO.0000000000001026","DOIUrl":"10.1097/MCO.0000000000001026","url":null,"abstract":"Purpose of review: This review provides the latest insight into the impact of consuming plant-based protein for older people.Recent findings: According to the latest data, a healthy diet rich in plant-based-protein-rich-food could promote healthy aging. This health effect is partly because of the amino acid composition of proteins, as well as to the important constituents such as fiber and bioactive compounds found in the matrix. Furthermore, even though animal protein is more effective at stimulating muscle protein synthesis, a high consumption of plant protein (beyond 31 g/day) appears to enhance physical performance and reduce the risk of frailty in older individuals.Summary: Recent literature highlights numerous health benefits for older people associated with a substantial intake of plant-based vs. animal-based protein, both in preventing and mitigating chronic age-related diseases and reducing the risk of all-cause mortality. However, a high intake of plant-based protein-rich products could pose risks of malnutrition and fiber-related intestinal intolerances. Further research is needed to assess the risk-benefit ratio of a high consumption of plant proteins in older individuals before we can make robust recommendations on how far animal proteins can be healthfully replaced with plant proteins.","PeriodicalId":10962,"journal":{"name":"Current Opinion in Clinical Nutrition and Metabolic Care","volume":" ","pages":"372-377"},"PeriodicalIF":3.1,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140058902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nutrition support, carbohydrate feeding and insulin sensitivity in the critically ill patient: a complex relationship. 重症患者的营养支持、碳水化合物喂养和胰岛素敏感性：复杂的关系。

IF 3.1 3区医学

Current Opinion in Clinical Nutrition and Metabolic Care Pub Date : 2024-07-01 Epub Date: 2024-05-07 DOI: 10.1097/MCO.0000000000001039

Ra'eesa Doola, Claire Dupuis, Jean-Charles Preiser

{"title":"Nutrition support, carbohydrate feeding and insulin sensitivity in the critically ill patient: a complex relationship.","authors":"Ra'eesa Doola, Claire Dupuis, Jean-Charles Preiser","doi":"10.1097/MCO.0000000000001039","DOIUrl":"10.1097/MCO.0000000000001039","url":null,"abstract":"Purpose of review: This review aims to summarize recent studies that highlight the complex relationship between nutrition, carbohydrate, insulin provision and glycaemic control in the critically ill patient population.Recent findings: Results of observational studies concur to support early hypoglycaemia and persisting hyperglycaemia as life-threatening events. In contrast, interventional studies indicate that early macronutrient restriction appears to reduce the benefits related to insulin therapy. This restriction is however associated with improved outcomes in itself. The potential role of modified enteral solutions as an adjunctive treatment to attenuate hyperglycaemia warrants further research. The selection of a therapeutic modality may also differ according to the characteristics of the setting, such as the nurse-to-patient ratio, the type and accuracy of meters, including near-continuous glucose monitoring and the availability of computer-guided protocols.Summary: There appears to be significant interplay between nutrition, including carbohydrate provision, blood glucose control and clinical outcomes. Individualized care is probably needed to define the optimal glucose target and nutritional intervention. This can differ according to the preexistence of chronic hyperglycaemia, the timing from the onset of critical illness and the clinical condition itself.","PeriodicalId":10962,"journal":{"name":"Current Opinion in Clinical Nutrition and Metabolic Care","volume":" ","pages":"350-354"},"PeriodicalIF":3.1,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140847239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The impact of slowly digestible and resistant starch on glucose homeostasis and insulin resistance. 慢消化淀粉和抗性淀粉对葡萄糖稳态和胰岛素抵抗的影响

IF 3.1 3区医学

Current Opinion in Clinical Nutrition and Metabolic Care Pub Date : 2024-07-01 Epub Date: 2024-06-06 DOI: 10.1097/MCO.0000000000001044

Maëliss Chisbert, Anne-Laure Castell, Sophie Vinoy, Julie-Anne Nazare

{"title":"The impact of slowly digestible and resistant starch on glucose homeostasis and insulin resistance.","authors":"Maëliss Chisbert, Anne-Laure Castell, Sophie Vinoy, Julie-Anne Nazare","doi":"10.1097/MCO.0000000000001044","DOIUrl":"10.1097/MCO.0000000000001044","url":null,"abstract":"Purpose of review: This review will summarize recent studies assessing the effect of slowly digestible starch (SDS) and resistant starch (RS) on glucose metabolism in healthy, prediabetic or type 2 diabetic adults.Recent findings: Currently, a particular interest in starch and its digestibility has arisen, with data showing a positive effect of SDS and RS on the glucose homeostasis of healthy, at-risk, prediabetic and type 2 diabetic patients but research is ongoing.Summary: Carbohydrates (CHO) and especially starch play a major role in the prevention and management of metabolic diseases such as type 2 diabetes (T2D). This largely depends on the quality and the digestibility (rate and extent) of the ingested starchy products, beyond their quantity. SDS have been poorly studied but display a beneficial effect on reducing glucose excursions in healthy and insulin-resistant subjects and a relevant potential to improve glucose control in type 2 diabetic individuals. As for RS, the results appear to be encouraging but remain heterogeneous, depending the nature of the RS and its role on microbiota modulation. Further studies are needed to confirm the present results and investigate the potential complementary beneficial effects of SDS and RS on long-term glucose homeostasis to prevent cardiometabolic diseases.","PeriodicalId":10962,"journal":{"name":"Current Opinion in Clinical Nutrition and Metabolic Care","volume":" ","pages":"338-343"},"PeriodicalIF":3.1,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11155281/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141247229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0