Critical Reviews in Microbiology最新文献_第2页

Peeling off the layers from microbial dark matter (MDM): recent advances, future challenges, and opportunities. 剥离微生物暗物质（MDM）的层次：最新进展、未来挑战和机遇。

IF 6 2区生物学

Critical Reviews in Microbiology Pub Date : 2025-02-01 Epub Date: 2024-02-22 DOI: 10.1080/1040841X.2024.2319669

Sajid Iqbal, Farida Begum, Ihsan Ullah, Nasir Jalal, Peter Shaw

{"title":"Peeling off the layers from microbial dark matter (MDM): recent advances, future challenges, and opportunities.","authors":"Sajid Iqbal, Farida Begum, Ihsan Ullah, Nasir Jalal, Peter Shaw","doi":"10.1080/1040841X.2024.2319669","DOIUrl":"10.1080/1040841X.2024.2319669","url":null,"abstract":"Microbes represent the most common organisms on Earth; however, less than 2% of microbial species in the environment can undergo cultivation for study under laboratory conditions, and the rest of the enigmatic, microbial world remains mysterious, constituting a kind of \"microbial dark matter\" (MDM). In the last two decades, remarkable progress has been made in culture-dependent and culture-independent techniques. More recently, studies of MDM have relied on culture-independent techniques to recover genetic material through either unicellular genomics or shotgun metagenomics to construct single-amplified genomes (SAGs) and metagenome-assembled genomes (MAGs), respectively, which provide information about evolution and metabolism. Despite the remarkable progress made in the past decades, the functional diversity of MDM still remains uncharacterized. This review comprehensively summarizes the recently developed culture-dependent and culture-independent techniques for characterizing MDM, discussing major challenges, opportunities, and potential applications. These activities contribute to expanding our knowledge of the microbial world and have implications for various fields including Biotechnology, Bioprospecting, Functional genomics, Medicine, Evolutionary and Planetary biology. Overall, this review aims to peel off the layers from MDM, shed light on recent advancements, identify future challenges, and illuminate the exciting opportunities that lie ahead in unraveling the secrets of this intriguing microbial realm.","PeriodicalId":10736,"journal":{"name":"Critical Reviews in Microbiology","volume":" ","pages":"1-21"},"PeriodicalIF":6.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139930392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vibrio cholerae virulence and its suppression through the quorum-sensing system. 霍乱弧菌的毒性及其通过法定人数感应系统的抑制作用。

IF 6 2区生物学

Critical Reviews in Microbiology Pub Date : 2025-02-01 Epub Date: 2024-03-05 DOI: 10.1080/1040841X.2024.2320823

Anusree Sajeevan, Thandavarayan Ramamurthy, Adline Princy Solomon

{"title":"Vibrio cholerae virulence and its suppression through the quorum-sensing system.","authors":"Anusree Sajeevan, Thandavarayan Ramamurthy, Adline Princy Solomon","doi":"10.1080/1040841X.2024.2320823","DOIUrl":"10.1080/1040841X.2024.2320823","url":null,"abstract":"Vibrio cholerae is a cholera-causing pathogen known to instigate severe contagious diarrhea that affects millions globally. Survival of vibrios depend on a combination of multicellular responses and adapt to changes that prevail in the environment. This process is achieved through a strong communication at the cellular level, the process has been recognized as quorum sensing (QS). The severity of infection is highly dependent on the QS of vibrios in the gut milieu. The quorum may exist in a low/high cell density (LCD/HCD) state to exert a positive or negative response to control the regulatory pathogenic networks. The impact of this regulation reflects on the transition of pathogenic V. cholerae from the environment to infect humans and cause outbreaks or epidemics of cholera. In this context, the review portrays various regulatory processes and associated virulent pathways, which maneuver and control LCD and HCD states for their survival in the host. Although several treatment options are existing, promotion of therapeutics by exploiting the virulence network may potentiate ineffective antibiotics to manage cholera. In addition, this approach is also useful in resource-limited settings, where the accessibility to antibiotics or conventional therapeutic options is limited.","PeriodicalId":10736,"journal":{"name":"Critical Reviews in Microbiology","volume":" ","pages":"22-43"},"PeriodicalIF":6.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140027552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The implication of microbiome in lungs cancer: mechanisms and strategies of cancer growth, diagnosis and therapy. 微生物组对肺癌的影响：癌症生长、诊断和治疗的机制与策略。

IF 6 2区生物学

Critical Reviews in Microbiology Pub Date : 2025-02-01 Epub Date: 2024-03-31 DOI: 10.1080/1040841X.2024.2324864

Yasmin Bano, Abhinav Shrivastava, Piyush Shukla, Anis Ahmad Chaudhary, Salah-Ud-Din Khan, Shahanavaj Khan

{"title":"The implication of microbiome in lungs cancer: mechanisms and strategies of cancer growth, diagnosis and therapy.","authors":"Yasmin Bano, Abhinav Shrivastava, Piyush Shukla, Anis Ahmad Chaudhary, Salah-Ud-Din Khan, Shahanavaj Khan","doi":"10.1080/1040841X.2024.2324864","DOIUrl":"10.1080/1040841X.2024.2324864","url":null,"abstract":"Available evidence illustrates that microbiome is a promising target for the study of growth, diagnosis and therapy of various types of cancer. Lung cancer is a leading cause of cancer death worldwide. The relationship of microbiota and their products with diverse pathologic conditions has been getting large attention. The novel research suggests that the microbiome plays an important role in the growth and progression of lung cancer. The lung microbiome plays a crucial role in maintaining mucosal immunity and synchronizing the stability between tolerance and inflammation. Alteration in microbiome is identified as a critical player in the progression of lung cancer and negatively impacts the patient. Studies suggest that healthy microbiome is essential for effective therapy. Various clinical trials and research are focusing on enhancing the treatment efficacy by altering the microbiome. The regulation of microbiota will provide innovative and promising treatment strategies for the maintenance of host homeostasis and the prevention of lung cancer in lung cancer patients. In the current review article, we presented the latest progress about the involvement of microbiome in the growth and diagnosis of lung cancer. Furthermore, we also assessed the therapeutic status of the microbiome for the management and treatment of lung cancer.","PeriodicalId":10736,"journal":{"name":"Critical Reviews in Microbiology","volume":" ","pages":"128-152"},"PeriodicalIF":6.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140331582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The diffusible signaling factor family in microbial signaling: a current perspective.

IF 6 2区生物学

Critical Reviews in Microbiology Pub Date : 2025-01-27 DOI: 10.1080/1040841X.2025.2457670

G K Wijesinghe, A H Nobbs, H M H N Bandara

{"title":"The diffusible signaling factor family in microbial signaling: a current perspective.","authors":"G K Wijesinghe, A H Nobbs, H M H N Bandara","doi":"10.1080/1040841X.2025.2457670","DOIUrl":"https://doi.org/10.1080/1040841X.2025.2457670","url":null,"abstract":"This review discusses the chemical properties, synthesis and detection, and biological functions of a molecular group of cis-2-unsaturated fatty acids, containing fatty acid carbon chains of various lengths and cis double-bond configurations, known as the diffusible signaling factor family (DSFF). Early postulation of the conserved nature of the DSFF among Gram-negative bacteria have now been challenged by the latest evidences that unraveled their presence in a various other distinct microorganisms. Over the last decade, a significant depth and breadth of understanding has been made on the multifaceted functions of DSFFs among bacteria, and their interactions with evolutionarily divergent fungi, plants insects and small animals. While the knowledge of the chemical nature and functions of DSFF within microbial systems is still developing, DSFF molecules such as BDSF, DSF, and SDSF have been found to modulate microbial virulence, cell adhesion, biofilm formation and dispersion, cell motility, and antimicrobial tolerance. Given their capacity to influence microbial ecosystems and the rapid emergence of novel DSFF-like molecules, it is critical to identify the full spectrum of DSFF members and to better understand the functions of this complex messenger system as they offer significant potential to be exploited in the development of new therapeutic strategies to combat the rising global healthcare threat of antimicrobial resistance. This narrative review therefore provides a broad picture of the DSFF quorum sensing with a core foundation built from seminal literature while highlighting the latest developments in the field.","PeriodicalId":10736,"journal":{"name":"Critical Reviews in Microbiology","volume":" ","pages":"1-16"},"PeriodicalIF":6.0,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143045510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The prospect of using nanotechnology to prevent and treat infections caused by Listeria monocytogenes. 利用纳米技术预防和治疗单核增生李斯特菌引起的感染的前景。

IF 6 2区生物学

Critical Reviews in Microbiology Pub Date : 2025-01-15 DOI: 10.1080/1040841X.2025.2452571

Mohammad Vaziri, Maryam Abedini Baghbadorani, Monireh Khandaee Ghamsari, Somayeh Handali

引用次数: 0

Could Neisseria gonorrhoeae have carcinogenic potential? A critical review of current evidence. 淋病奈瑟菌有致癌潜力吗？对现有证据的批判性回顾。

IF 6 2区生物学

Critical Reviews in Microbiology Pub Date : 2025-01-08 DOI: 10.1080/1040841X.2024.2448166

Alexander Ngoo, Evgeny A Semchenko, Anthony Atack, Patrick B Thomas, Kate L Seib, Ian Vela, Elizabeth D Williams

引用次数: 0

Recent progress in understanding the role of bacterial extracellular DNA: focus on dental biofilm. 细菌细胞外DNA作用的最新研究进展：以口腔生物膜为中心。

IF 6 2区生物学

Critical Reviews in Microbiology Pub Date : 2024-12-08 DOI: 10.1080/1040841X.2024.2438117

Fengxue Geng, Junchao Liu, Jinwen Liu, Ze Lu, Yaping Pan

引用次数: 0

Microbial biosynthesis of nucleos(t)ide analogs: applications, and engineering optimization. 微生物合成核苷类似物：应用和工程优化。

IF 6 2区生物学

Critical Reviews in Microbiology Pub Date : 2024-12-01 DOI: 10.1080/1040841X.2024.2435668

Wenbin Yu, Xiang Wei, Yichuan Wu, Chunmiao Jiang, Yayi Tu, Bin He

{"title":"Microbial biosynthesis of nucleos(t)ide analogs: applications, and engineering optimization.","authors":"Wenbin Yu, Xiang Wei, Yichuan Wu, Chunmiao Jiang, Yayi Tu, Bin He","doi":"10.1080/1040841X.2024.2435668","DOIUrl":"https://doi.org/10.1080/1040841X.2024.2435668","url":null,"abstract":"Nucleos(t)ide analogs constitute a diverse group of compounds derived from nucleosides and nucleotides, playing a crucial role in various biological processes. These analogs exhibit a wide range of applications, including their use as additives, antiviral, and anticancer agents, which makes them valuable in food and medical research. In this review, we will explore the applications of nucleos(t)ide analogs across different fields and discuss the latest advances in engineering and optimization strategies aimed at improving their production efficiency and tailoring their properties for specific purposes. The article focuses on the design of microbial cell factories and their critical role in the production of nucleos(t)ide analogs. By leveraging microbial biosynthesis pathways and employing strategies such as metabolic engineering, researchers are optimizing the synthesis pathways of nucleos(t)ide analogs. This optimization enhances both the yield and diversity of nucleos(t)ide analogs, leading to the creation of novel compounds with enhanced bioactivity and therapeutic potential. Consequently, these efforts are driving significant advancements in drug discovery and biotechnology.","PeriodicalId":10736,"journal":{"name":"Critical Reviews in Microbiology","volume":" ","pages":"1-19"},"PeriodicalIF":6.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142766682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Extracellular vesicle production by oral bacteria related to dental caries and periodontal disease: role in microbe-host and interspecies interactions. 与龋齿和牙周病有关的口腔细菌产生的胞外囊泡：在微生物-宿主和种间相互作用中的作用。

IF 6 2区生物学

Critical Reviews in Microbiology Pub Date : 2024-11-20 DOI: 10.1080/1040841X.2024.2427656

Camila Leiva-Sabadini, Paula Saavedra, Carla Inostroza, Sebastian Aguayo

{"title":"Extracellular vesicle production by oral bacteria related to dental caries and periodontal disease: role in microbe-host and interspecies interactions.","authors":"Camila Leiva-Sabadini, Paula Saavedra, Carla Inostroza, Sebastian Aguayo","doi":"10.1080/1040841X.2024.2427656","DOIUrl":"https://doi.org/10.1080/1040841X.2024.2427656","url":null,"abstract":"Extracellular vesicles (EVs) are cell membrane-derived structures between 20-400 nm in size. In bacteria, EVs play a crucial role in molecule secretion, cell wall biogenesis, cell-cell communication, biofilm development, and host-pathogen interactions. Despite these increasing reports of bacterial-derived vesicles, there remains a limited number of studies that summarize oral bacterial EVs, their cargo, and their main biological functions. Therefore, the aim of this review is to present the latest research on oral bacteria-derived EVs and how they can modulate various physiological and pathological processes in the oral cavity, including the pathogenesis of highly relevant diseases such as dental caries and periodontitis and their systemic complications. Overall, caries-associated bacteria (such as Streptococcus mutans) as well as periodontal pathogens (including the red complex pathogens Porphyromonas gingivalis, Tannerella forsythia, and Treponema denticola) have all been shown to produce EVs that carry an array of virulent factors and molecules involved in biofilm and immune modulation, bacterial adhesion, and extracellular matrix degradation. As bacterial EV production is strongly impacted by genotypic and environmental variations, the inhibition of EV genesis and secretion remains a key potential future approach against oral diseases.","PeriodicalId":10736,"journal":{"name":"Critical Reviews in Microbiology","volume":" ","pages":"1-18"},"PeriodicalIF":6.0,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142675192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Targeting bioinformatics tools to study the dissemination and spread of antibiotic resistant genes in the environment and clinical settings. 以生物信息学工具为目标，研究抗生素耐药基因在环境和临床环境中的传播和扩散。

IF 6 2区生物学

Critical Reviews in Microbiology Pub Date : 2024-11-18 DOI: 10.1080/1040841X.2024.2429603

Chandra Kant Singh, Kushneet Kaur Sodhi

{"title":"Targeting bioinformatics tools to study the dissemination and spread of antibiotic resistant genes in the environment and clinical settings.","authors":"Chandra Kant Singh, Kushneet Kaur Sodhi","doi":"10.1080/1040841X.2024.2429603","DOIUrl":"https://doi.org/10.1080/1040841X.2024.2429603","url":null,"abstract":"Antibiotic resistance has expanded as a result of the careless use of antibiotics in the medical field, the food industry, agriculture, and other industries. By means of genetic recombination between commensal and pathogenic bacteria, the microbes obtain antibiotic resistance genes (ARGs). In bacteria, horizontal gene transfer (HGT) is the main mechanism for acquiring ARGs. With the development of high-throughput sequencing, ARG sequence analysis is now feasible and widely available. Preventing the spread of AMR in the environment requires the implementation of ARGs mapping. The metagenomic technique, in particular, has helped in identifying antibiotic resistance within microbial communities. Due to the exponential growth of experimental and clinical data, significant investments in computer capacity, and advancements in algorithmic techniques, the application of machine learning (ML) algorithms to the problem of AMR has attracted increasing attention over the past five years. The review article sheds a light on the application of bioinformatics for the antibiotic resistance monitoring. The most advanced tool currently being employed to catalog the resistome of various habitats are metagenomics and metatranscriptomics. The future lies in the hands of artificial intelligence (AI) and machine learning (ML) methods, to predict and optimize the interaction of antibiotic-resistant compounds with target proteins.","PeriodicalId":10736,"journal":{"name":"Critical Reviews in Microbiology","volume":" ","pages":"1-19"},"PeriodicalIF":6.0,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142647290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0