Critical Reviews in Microbiology最新文献

Extracellular vesicle production by oral bacteria related to dental caries and periodontal disease: role in microbe-host and interspecies interactions. 与龋齿和牙周病有关的口腔细菌产生的胞外囊泡：在微生物-宿主和种间相互作用中的作用。

IF 6 2区生物学

Critical Reviews in Microbiology Pub Date : 2024-11-20 DOI: 10.1080/1040841X.2024.2427656

Camila Leiva-Sabadini, Paula Saavedra, Carla Inostroza, Sebastian Aguayo

{"title":"Extracellular vesicle production by oral bacteria related to dental caries and periodontal disease: role in microbe-host and interspecies interactions.","authors":"Camila Leiva-Sabadini, Paula Saavedra, Carla Inostroza, Sebastian Aguayo","doi":"10.1080/1040841X.2024.2427656","DOIUrl":"https://doi.org/10.1080/1040841X.2024.2427656","url":null,"abstract":"Extracellular vesicles (EVs) are cell membrane-derived structures between 20-400 nm in size. In bacteria, EVs play a crucial role in molecule secretion, cell wall biogenesis, cell-cell communication, biofilm development, and host-pathogen interactions. Despite these increasing reports of bacterial-derived vesicles, there remains a limited number of studies that summarize oral bacterial EVs, their cargo, and their main biological functions. Therefore, the aim of this review is to present the latest research on oral bacteria-derived EVs and how they can modulate various physiological and pathological processes in the oral cavity, including the pathogenesis of highly relevant diseases such as dental caries and periodontitis and their systemic complications. Overall, caries-associated bacteria (such as Streptococcus mutans) as well as periodontal pathogens (including the red complex pathogens Porphyromonas gingivalis, Tannerella forsythia, and Treponema denticola) have all been shown to produce EVs that carry an array of virulent factors and molecules involved in biofilm and immune modulation, bacterial adhesion, and extracellular matrix degradation. As bacterial EV production is strongly impacted by genotypic and environmental variations, the inhibition of EV genesis and secretion remains a key potential future approach against oral diseases.","PeriodicalId":10736,"journal":{"name":"Critical Reviews in Microbiology","volume":" ","pages":"1-18"},"PeriodicalIF":6.0,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142675192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Targeting bioinformatics tools to study the dissemination and spread of antibiotic resistant genes in the environment and clinical settings. 以生物信息学工具为目标，研究抗生素耐药基因在环境和临床环境中的传播和扩散。

IF 6 2区生物学

Critical Reviews in Microbiology Pub Date : 2024-11-18 DOI: 10.1080/1040841X.2024.2429603

Chandra Kant Singh, Kushneet Kaur Sodhi

{"title":"Targeting bioinformatics tools to study the dissemination and spread of antibiotic resistant genes in the environment and clinical settings.","authors":"Chandra Kant Singh, Kushneet Kaur Sodhi","doi":"10.1080/1040841X.2024.2429603","DOIUrl":"https://doi.org/10.1080/1040841X.2024.2429603","url":null,"abstract":"Antibiotic resistance has expanded as a result of the careless use of antibiotics in the medical field, the food industry, agriculture, and other industries. By means of genetic recombination between commensal and pathogenic bacteria, the microbes obtain antibiotic resistance genes (ARGs). In bacteria, horizontal gene transfer (HGT) is the main mechanism for acquiring ARGs. With the development of high-throughput sequencing, ARG sequence analysis is now feasible and widely available. Preventing the spread of AMR in the environment requires the implementation of ARGs mapping. The metagenomic technique, in particular, has helped in identifying antibiotic resistance within microbial communities. Due to the exponential growth of experimental and clinical data, significant investments in computer capacity, and advancements in algorithmic techniques, the application of machine learning (ML) algorithms to the problem of AMR has attracted increasing attention over the past five years. The review article sheds a light on the application of bioinformatics for the antibiotic resistance monitoring. The most advanced tool currently being employed to catalog the resistome of various habitats are metagenomics and metatranscriptomics. The future lies in the hands of artificial intelligence (AI) and machine learning (ML) methods, to predict and optimize the interaction of antibiotic-resistant compounds with target proteins.","PeriodicalId":10736,"journal":{"name":"Critical Reviews in Microbiology","volume":" ","pages":"1-19"},"PeriodicalIF":6.0,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142647290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antibiotic resistance in Pseudomonas aeruginosa: mechanisms and emerging treatment. 铜绿假单胞菌的抗生素耐药性：机制和新的治疗方法。

IF 6 2区生物学

Critical Reviews in Microbiology Pub Date : 2024-11-18 DOI: 10.1080/1040841X.2024.2429599

Jian Yang, Jin-Fu Xu, Shuo Liang

{"title":"Antibiotic resistance in Pseudomonas aeruginosa: mechanisms and emerging treatment.","authors":"Jian Yang, Jin-Fu Xu, Shuo Liang","doi":"10.1080/1040841X.2024.2429599","DOIUrl":"https://doi.org/10.1080/1040841X.2024.2429599","url":null,"abstract":"Pseudomonas aeruginosa, able to survive on the surfaces of medical devices, is a life-threatening pathogen that mainly leads to nosocomial infection especially in immunodeficient and cystic fibrosis (CF) patients. The antibiotic resistance in P. aeruginosa has become a world-concerning problem, which results in reduced and ineffective therapy efficacy. Besides intrinsic properties to decrease the intracellular content and activity of antibiotics, P. aeruginosa develops acquired resistance by gene mutation and acquisition, as well as adaptive resistance under specific situations. With in-depth research on drug resistance mechanisms and the development of biotechnology, innovative strategies have emerged and yielded benefits such as screening for new antibiotics based on artificial intelligence technology, utilizing drugs synergistically, optimizing administration, and developing biological therapy. This review summarizes the recent advances in the mechanisms of antibiotic resistance and emerging treatments for combating resistance, aiming to provide a reference for the development of therapy against drug-resistant P. aeruginosa.","PeriodicalId":10736,"journal":{"name":"Critical Reviews in Microbiology","volume":" ","pages":"1-19"},"PeriodicalIF":6.0,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142647273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of bacterial extracellular vesicles in promoting antibiotic resistance. 细菌胞外囊泡在促进抗生素耐药性方面的作用。

IF 6 2区生物学

Critical Reviews in Microbiology Pub Date : 2024-11-04 DOI: 10.1080/1040841X.2024.2423159

Shaoqi Qu, Yanfang Zhang, Liangyun Weng, Xinxin Shan, Ping Cheng, Qian Li, Lin Li

{"title":"The role of bacterial extracellular vesicles in promoting antibiotic resistance.","authors":"Shaoqi Qu, Yanfang Zhang, Liangyun Weng, Xinxin Shan, Ping Cheng, Qian Li, Lin Li","doi":"10.1080/1040841X.2024.2423159","DOIUrl":"https://doi.org/10.1080/1040841X.2024.2423159","url":null,"abstract":"The burgeoning proliferation of infections attributed to multidrug-resistant (MDR) bacterial pathogens is profoundly undermining conventional chemotherapeutic modalities, portending a grave menace to global public health. The propagation of drug resistance among bacteria is fundamentally facilitated by bacterial interactions, with extracellular vesicles (EVs) assuming a critical role in interbacterial communication. Here, we briefly delineate the methodologies for isolation, extraction, and characterization of EVs from both Gram-negative and Gram-positive bacterial origins. We further investigate assorted methodologies to augment EV production, embracing physical stimulation, chemical elicitation, and genetic engineering. Moreover, we expound on the pivotal involvement of EVs in the facilitation of bacterial drug resistance proliferation and anticipate future trajectories of research and application potential. This overview of EV-mediated novel mechanisms of horizontal gene transfer implicated in antibiotic resistance among bacteria aims to obstruct the transmission conduits of bacterial drug resistance and thus fortify public health integrity.","PeriodicalId":10736,"journal":{"name":"Critical Reviews in Microbiology","volume":" ","pages":"1-18"},"PeriodicalIF":6.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142575034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Molecular imaging of bacterial biofilms-a systematic review. 细菌生物膜的分子成像--系统综述。

IF 6 2区生物学

Critical Reviews in Microbiology Pub Date : 2024-11-01 Epub Date: 2023-07-15 DOI: 10.1080/1040841X.2023.2223704

S W G van Hoogstraten, C Kuik, J J C Arts, B Cillero-Pastor

{"title":"Molecular imaging of bacterial biofilms-a systematic review.","authors":"S W G van Hoogstraten, C Kuik, J J C Arts, B Cillero-Pastor","doi":"10.1080/1040841X.2023.2223704","DOIUrl":"10.1080/1040841X.2023.2223704","url":null,"abstract":"The formation of bacterial biofilms in the human body and on medical devices is a serious human health concern. Infections related to bacterial biofilms are often chronic and difficult to treat. Detailed information on biofilm formation and composition over time is essential for a fundamental understanding of the underlying mechanisms of biofilm formation and its response to anti-biofilm therapy. However, information on the chemical composition, structural components of biofilms, and molecular interactions regarding metabolism- and communication pathways within the biofilm, such as uptake of administered drugs or inter-bacteria communication, remains elusive. Imaging these molecules and their distribution in the biofilm increases insight into biofilm development, growth, and response to environmental factors or drugs. This systematic review provides an overview of molecular imaging techniques used for bacterial biofilm imaging. The techniques included mass spectrometry-based techniques, fluorescence-labelling techniques, spectroscopic techniques, nuclear magnetic resonance spectroscopy (NMR), micro-computed tomography (µCT), and several multimodal approaches. Many molecules were imaged, such as proteins, lipids, metabolites, and quorum-sensing (QS) molecules, which are crucial in intercellular communication pathways. Advantages and disadvantages of each technique, including multimodal approaches, to study molecular processes in bacterial biofilms are discussed, and recommendations on which technique best suits specific research aims are provided.","PeriodicalId":10736,"journal":{"name":"Critical Reviews in Microbiology","volume":" ","pages":"971-992"},"PeriodicalIF":6.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11523921/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10137108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction. 更正。

IF 6 2区生物学

Critical Reviews in Microbiology Pub Date : 2024-11-01 Epub Date: 2024-03-20 DOI: 10.1080/1040841X.2024.2329036

引用次数: 0

Non-antibiotic compounds associated with humans and the environment can promote horizontal transfer of antimicrobial resistance genes. 与人类和环境相关的非抗生素化合物可促进抗菌药耐药性基因的水平转移。

IF 6 2区生物学

Critical Reviews in Microbiology Pub Date : 2024-11-01 Epub Date: 2023-07-18 DOI: 10.1080/1040841X.2023.2233603

Ilyas Alav, Michelle M C Buckner

{"title":"Non-antibiotic compounds associated with humans and the environment can promote horizontal transfer of antimicrobial resistance genes.","authors":"Ilyas Alav, Michelle M C Buckner","doi":"10.1080/1040841X.2023.2233603","DOIUrl":"10.1080/1040841X.2023.2233603","url":null,"abstract":"Horizontal gene transfer plays a key role in the global dissemination of antimicrobial resistance (AMR). AMR genes are often carried on self-transmissible plasmids, which are shared amongst bacteria primarily by conjugation. Antibiotic use has been a well-established driver of the emergence and spread of AMR. However, the impact of commonly used non-antibiotic compounds and environmental pollutants on AMR spread has been largely overlooked. Recent studies found common prescription and over-the-counter drugs, artificial sweeteners, food preservatives, and environmental pollutants, can increase the conjugative transfer of AMR plasmids. The potential mechanisms by which these compounds promote plasmid transmission include increased membrane permeability, upregulation of plasmid transfer genes, formation of reactive oxygen species, and SOS response gene induction. Many questions remain around the impact of most non-antibiotic compounds on AMR plasmid conjugation in clinical isolates and the long-term impact on AMR dissemination. By elucidating the role of routinely used pharmaceuticals, food additives, and pollutants in the dissemination of AMR, action can be taken to mitigate their impact by closely monitoring use and disposal. This review will discuss recent progress on understanding the influence of non-antibiotic compounds on plasmid transmission, the mechanisms by which they promote transfer, and the level of risk they pose.","PeriodicalId":10736,"journal":{"name":"Critical Reviews in Microbiology","volume":" ","pages":"993-1010"},"PeriodicalIF":6.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11523920/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9825229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Current types of staphylococcal cassette chromosome mec (SCCmec) in clinically relevant coagulase-negative staphylococcal (CoNS) species. 临床相关凝固酶阴性葡萄球菌（CoNS）种中葡萄球菌盒染色体mec（SCCmec）的当前类型。

IF 6 2区生物学

Critical Reviews in Microbiology Pub Date : 2024-11-01 Epub Date: 2023-10-26 DOI: 10.1080/1040841X.2023.2274841

Mariola Wolska-Gębarzewska, Jacek Międzobrodzki, Maja Kosecka-Strojek

{"title":"Current types of staphylococcal cassette chromosome mec (SCCmec) in clinically relevant coagulase-negative staphylococcal (CoNS) species.","authors":"Mariola Wolska-Gębarzewska, Jacek Międzobrodzki, Maja Kosecka-Strojek","doi":"10.1080/1040841X.2023.2274841","DOIUrl":"10.1080/1040841X.2023.2274841","url":null,"abstract":"Coagulase-negative staphylococci (CoNS) colonize human skin and mucosal membranes, which is why they are considered harmless commensal bacteria. Two species, Staphylococcus epidermidis and Staphylococcus haemolyticus belong to the group of CoNS species and are most frequently isolated from nosocomial infections, including device-associated healthcare-associated infections (DA-HAIs) and local or systemic body-related infections (FBRIs). Methicillin resistance, initially described in Staphylococcus aureus, has also been reported in CoNS species. It is mediated by the mecA gene within the staphylococcal cassette chromosome (SCCmec). SCCmec typing, primarily using PCR-based methods, has been employed as a molecular epidemiological tool. However, the introduction of whole genome sequencing (WGS) and next-generation sequencing (NGS) has enabled the identification and verification of new SCCmec types. This review describes the current distribution of SCCmec types, subtypes, and variants among CoNS species, including S. epidermidis, S. haemolyticus, and S. capitis. The literature review focuses on recent research articles from the past decade that discuss new combinations of SCCmec in coagulase-negative Staphylococcus. The high genetic diversity and gaps in CoNS SCCmec annotation rules underscore the need for an efficient typing system. Typing SCCmec cassettes in CoNS strains is crucial to continuously updating databases and developing a unified classification system.","PeriodicalId":10736,"journal":{"name":"Critical Reviews in Microbiology","volume":" ","pages":"1020-1036"},"PeriodicalIF":6.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50161020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Type IV pili are involved in phenotypes associated with Clostridioides difficile pathogenesis. IV 型纤毛虫与艰难梭状芽孢杆菌发病机制相关的表型有关。

IF 6 2区生物学

Critical Reviews in Microbiology Pub Date : 2024-11-01 Epub Date: 2023-07-15 DOI: 10.1080/1040841X.2023.2235002

Zirou Ouyang, Hanlin Zhao, Min Zhao, Yaxuan Yang, Jianhong Zhao

引用次数: 0

Tumor-targeting bacteria as immune stimulants - the future of cancer immunotherapy? 作为免疫刺激剂的肿瘤靶向细菌--癌症免疫疗法的未来？

IF 6 2区生物学

Critical Reviews in Microbiology Pub Date : 2024-11-01 Epub Date: 2024-02-12 DOI: 10.1080/1040841X.2024.2311653

Alexandra M Mowday, Jella M van de Laak, Zhe Fu, Kimiora L Henare, Ludwig Dubois, Philippe Lambin, Jan Theys, Adam V Patterson

{"title":"Tumor-targeting bacteria as immune stimulants - the future of cancer immunotherapy?","authors":"Alexandra M Mowday, Jella M van de Laak, Zhe Fu, Kimiora L Henare, Ludwig Dubois, Philippe Lambin, Jan Theys, Adam V Patterson","doi":"10.1080/1040841X.2024.2311653","DOIUrl":"10.1080/1040841X.2024.2311653","url":null,"abstract":"Cancer immunotherapies have been widely hailed as a breakthrough for cancer treatment in the last decade, epitomized by the unprecedented results observed with checkpoint blockade. Even so, only a minority of patients currently achieve durable remissions. In general, responsive patients appear to have either a high number of tumor neoantigens, a preexisting immune cell infiltrate in the tumor microenvironment, or an 'immune-active' transcriptional profile, determined in part by the presence of a type I interferon gene signature. These observations suggest that the therapeutic efficacy of immunotherapy can be enhanced through strategies that release tumor neoantigens and/or produce a pro-inflammatory tumor microenvironment. In principle, exogenous tumor-targeting bacteria offer a unique solution for improving responsiveness to immunotherapy. This review discusses how tumor-selective bacterial infection can modulate the immunological microenvironment of the tumor and the potential for combination with cancer immunotherapy strategies to further increase therapeutic efficacy. In addition, we provide a perspective on the clinical translation of replicating bacterial therapies, with a focus on the challenges that must be resolved to ensure a successful outcome.","PeriodicalId":10736,"journal":{"name":"Critical Reviews in Microbiology","volume":" ","pages":"955-970"},"PeriodicalIF":6.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11523919/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139721977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0