Coronary artery disease最新文献_第7页

Endothelial progenitor cells have high predictive value for ventricular remodeling after percutaneous coronary intervention in acute myocardial infarction. 内皮祖细胞对急性心肌梗死经皮冠状动脉介入治疗后的心室重塑具有很高的预测价值。

IF 1.5 4区医学

Coronary artery disease Pub Date : 2024-12-17 DOI: 10.1097/MCA.0000000000001461

Yongxiang Ma, Lijian Niu, Jing Zhang, Fei Yu, Wenjun Huang

{"title":"Endothelial progenitor cells have high predictive value for ventricular remodeling after percutaneous coronary intervention in acute myocardial infarction.","authors":"Yongxiang Ma, Lijian Niu, Jing Zhang, Fei Yu, Wenjun Huang","doi":"10.1097/MCA.0000000000001461","DOIUrl":"10.1097/MCA.0000000000001461","url":null,"abstract":"Objective: Acute myocardial infarction (AMI) and the following heart failure are main causes of disability and death across the globe. Endothelial progenitor cell (EPC) levels are linked to AMI. Herein, we assessed the predictive value of EPCs for post-percutaneous coronary intervention (PCI) ventricular remodeling in AMI patients.Methods: This study retrospectively analyzed 215 AMI patients receiving PCI, who were then categorized into the VR ( n = 66) and N-VR ( n = 149) groups as per whether they developed post-PCI ventricular remodeling. Left ventricular ejection fraction (LVEF), N-terminal pro-brain natriuretic peptide (NT-pro-BNP), and EPCs were measured. The correlations of LVEF and NT-pro-BNP with EPCs, the predictive value of EPCs for post-PCI ventricular remodeling, and the risk of post-PCI ventricular remodeling in AMI patients with different EPC levels were analyzed by Spearman's analysis, receiver-operating characteristic curve, and Kaplan-Meier curve.Results: LVEF and EPC levels were lower and NT-pro-BNP level was higher in the VR group than the N-VR group. EPC levels in the class III-IV group were lower than those in the class I-II group. EPC levels in AMI patients correlated positively with LVEF ( r = 0.683) and negatively with NT-pro-BNP ( r = -0.761). EPCs exhibited high predictive value for post-PCI ventricular remodeling in AMI [area under the curve (AUC) of 0.822] and anterior MI (AUC = 0.941) patients. AMI and anterior MI patients with low EPC levels had a higher risk of post-PCI ventricular remodeling.Conclusion: Low EPC levels have high predictive value for post-PCI ventricular remodeling, and increase the risk of post-PCI ventricular remodeling in AMI patients.","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142827647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Management of woven coronary bifurcation lesion with mini-crush technique. 小挤压技术治疗编织冠状动脉分叉病变。

IF 1.5 4区医学

Coronary artery disease Pub Date : 2024-12-12 DOI: 10.1097/MCA.0000000000001467

Ahmet Yaşar Çizgici, Koray Çiloğlu, Ahmet Güner, Serkan Yazan, Berkay Serter, Cemalettin Akman, Ezgi Gültekin Güner, Hande Uysal, İbrahim Faruk Aktürk, Fatih Uzun

引用次数: 0

A rare finding after acute myocardial infarction. 急性心肌梗塞后罕见发现。

IF 1.5 4区医学

Coronary artery disease Pub Date : 2024-12-05 DOI: 10.1097/MCA.0000000000001473

Diamantis Kosmidis, Nikolaos Gouliaros, Evangelia Sotiroglou, Dimitris Vatitsis, Charalampos Stefanidis, Christos Chatzieleftheriou

引用次数: 0

Hair cortisol concentration, a stress biomarker, is gradually increasing before an acute myocardial infarction. 毛发皮质醇浓度，一种应激生物标志物，在急性心肌梗死前逐渐升高。

IF 1.5 4区医学

Coronary artery disease Pub Date : 2024-12-03 DOI: 10.1097/MCA.0000000000001468

Nikolaos Kosmas, Panagiotis Simitsis, Evangelos Alevyzakis, Emmanouil Rizos, Dimitrios Zapantiotis, Loukianos Stylianos Rallidis

{"title":"Hair cortisol concentration, a stress biomarker, is gradually increasing before an acute myocardial infarction.","authors":"Nikolaos Kosmas, Panagiotis Simitsis, Evangelos Alevyzakis, Emmanouil Rizos, Dimitrios Zapantiotis, Loukianos Stylianos Rallidis","doi":"10.1097/MCA.0000000000001468","DOIUrl":"https://doi.org/10.1097/MCA.0000000000001468","url":null,"abstract":"Background: Chronic stress is believed to play a role in the pathophysiology of acute myocardial infarction (AMI). Cortisol is a biomarker associated with stress. We sought to assess stress contribution to AMI using hair cortisol concentration (HCCs) as a surrogate biomarker.Methods: HCC was measured in hair segments, corresponding to distinctive periods before hair sampling, in 102 male AMI patients and 50 healthy male controls. Standard baseline variables were collected for both groups, whereas for AMI patients, laboratory and psychological tests were also carried out. Linear mixed models were applied to assess the effect of group and baseline variables on the trend of cortisol before hair sampling.Results: HCC was significantly higher in AMI patients the last 30 days before hair sampling with an overall higher rate of increase (time-group interaction P < 0.001). AMI patients with BMI ≥25 kg/m2 had a slower rate of increase compared with those with BMI <25 kg/m2 (adjusted P = 0.008). Among AMI patients, there was no difference in the rate of cortisol increase between STEMI and NSTEMI patients (time-group interaction P = 0.841). Lower BMI conferred higher rates of cortisol increase irrespectively of AMI type.Conclusion: HCC, a biomarker of stress, showed an increasing trend over a period of 2 months before the occurrence of AMI suggesting a potential role of stress, through cortisol secretion, in the pathophysiology of AMI.","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142767006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Serum malondialdehyde levels at admission as a predictor of inhospital mortality in patients with acute coronary syndrome. 入院时血清丙二醛水平作为急性冠状动脉综合征患者住院死亡率的预测因子

IF 1.5 4区医学

Coronary artery disease Pub Date : 2024-12-03 DOI: 10.1097/MCA.0000000000001469

Muammer Karakayali, Metin Ogun, Inanç Artac, Doğan Ilis, Ayca Arslan, Timor Omar, Öztürk Demir, Talha Karahan, Soner Kina, Ibrahim Rencuzogullari, Yavuz Karabag

{"title":"Serum malondialdehyde levels at admission as a predictor of inhospital mortality in patients with acute coronary syndrome.","authors":"Muammer Karakayali, Metin Ogun, Inanç Artac, Doğan Ilis, Ayca Arslan, Timor Omar, Öztürk Demir, Talha Karahan, Soner Kina, Ibrahim Rencuzogullari, Yavuz Karabag","doi":"10.1097/MCA.0000000000001469","DOIUrl":"https://doi.org/10.1097/MCA.0000000000001469","url":null,"abstract":"Introduction and objective: Malondialdehyde (MDA) is a predictive marker of cardiovascular events in patients with stable angina pectoris. However, there is limited information available regarding this marker in patients with acute coronary syndrome (ACS). The aim of the study was to explore the association of MDA levels with inhospital mortality among patients with ACS.Materials and methods: The study sample consisted of 556 ACS patients. The leftover plasma samples collected in EDTA vials for troponin T estimation within 24 h of chest pain were used for analysis. Blood samples were collected into tubes for MDA, nitric oxide (NO), inducible nitric oxide synthase (i-NOS), endothelial nitric oxide synthase (e-NOS), total sialic acid (TSA), NT-proBNP, ANP, homocysteine, and cardiac troponin I (cTnI). The blood samples were centrifuged (4000g, 4 °C) for 10 min, and the obtained serum then kept at -25 °C until the analyses were carried out. The relationship between these markers and inhospital mortality of ACS patients was investigated.Results: Univariate logistic regression analysis revealed significant correlations among sex, age, creatine, MDA, NT-proBNP, ANP, homocysteine, cTnI, NO, e-NOS, i-NOS, and TSA. Further analysis of these variables using the multivariate logistic regression analysis indicated that age, creatine, MDA, and NT-proBNP were independent predictors. Optimal MDA cutoff value of >33.1 predicted inhospital mortality with 85% sensitivity and 88.17% specificity [AUC: 0.905 (95% CI: 0.878-0.928, P < 0.001)].Conclusion: We demonstrated that MDA levels were elevated in cases of inhospital mortality among ACS patients and the optimal MDA cutoff value of >33.1 predicted inhospital mortality with 85% sensitivity and 88.17% specificity.","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142767086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The unnecessary bypass surgery and the competition between native vessel and surgical graft flow. 不必要的搭桥手术和原生血管与移植血流的竞争。

IF 1.5 4区医学

Coronary artery disease Pub Date : 2024-12-02 DOI: 10.1097/MCA.0000000000001470

Konstantinos C Theodoropoulos, Matthaios Didagelos, Konstantinos Tsakiridis, Charalambos Kakderis, Alexandra Liakopoulou, Elizabeth Psoma, George Kassimis, Antonios Ziakas

引用次数: 0

Effect of PCSK9 inhibitors on major cardiac adverse events and lipoprotein-a in patients with coronary heart disease: a meta-analysis. PCSK9抑制剂对冠心病患者主要心脏不良事件和脂蛋白-a的影响：一项荟萃分析

IF 1.5 4区医学

Coronary artery disease Pub Date : 2024-12-02 DOI: 10.1097/MCA.0000000000001464

Enze Hu, Macao Wan

{"title":"Effect of PCSK9 inhibitors on major cardiac adverse events and lipoprotein-a in patients with coronary heart disease: a meta-analysis.","authors":"Enze Hu, Macao Wan","doi":"10.1097/MCA.0000000000001464","DOIUrl":"https://doi.org/10.1097/MCA.0000000000001464","url":null,"abstract":"Background: Lipoprotein(a) [Lp(a)] is an independent risk factor for cardiovascular disease due to its unique apo(a) component and its association with atherosclerosis and thrombogenesis. This meta-analysis was conducted to evaluate the effects of PCSK9 inhibitors on major adverse cardiac events (MACE) and Lp(a) levels in patients with coronary heart disease.Methods: Randomized controlled trials (RCTs) were systematically searched in PubMed, the Cochrane Library, and other databases. Stata 15.1 software was used for data analysis, and a random- or fixed-effects model was selected based on inter-study heterogeneity. Egger's test was applied to detect publication bias.Results: A total of 12 RCTs were included, involving 48 116 patients with a mean age of 62 years, comprising 65% males and diverse ethnic backgrounds. The results showed that compared with the control group, PCSK9 inhibitors significantly reduced low-density lipoprotein cholesterol (WMD = -1.24 mmol/L, 95% confidence interval (CI): -1.28 to -1.20), total cholesterol, triglycerides, and Lp(a) levels while increasing high-density lipoprotein cholesterol levels. In terms of safety, there was no increased risk of adverse reactions other than injection site reactions. For MACE, PCSK9 inhibitors significantly reduced the risk of nonfatal myocardial infarction, stroke, and coronary revascularization events (RR = 0.87, 95% CI: 0.84-0.89).Conclusion: PCSK9 inhibitors not only significantly improve blood lipid profiles and reduce Lp(a) levels but also reduce the risk of MACE in patients with coronary heart disease. Therefore, PCSK9 inhibitors offer an effective and safe treatment option for these patients.","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142767004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Inferior ST elevation myocardial infarction in a patient with anomalous origin of the left coronary artery from the right coronary cusp. 一名左冠状动脉从右冠状动脉尖异常起源的患者发生下行 ST 段抬高型心肌梗死。

IF 1.5 4区医学

Coronary artery disease Pub Date : 2024-12-01 Epub Date: 2024-07-09 DOI: 10.1097/MCA.0000000000001408

George Kassimis, Athanasios Samaras, Athina Nasoufidou, Konstantinos C Theodoropoulos, Matthaios Didagelos, Georgios P Rampidis, Antonios Ziakas, Nikolaos Fragakis

引用次数: 0

Vigilance against coronary heart disease in patients with multiple tuberous xanthomas. 警惕多发性结节性黄瘤患者的冠心病。

IF 1.5 4区医学

Coronary artery disease Pub Date : 2024-12-01 Epub Date: 2024-05-15 DOI: 10.1097/MCA.0000000000001387

Feng-Zeng Li, Kai-Yi Zhou, Sheng Fang

引用次数: 0

Coronary angiography-derived microvascular assessment (IMR angio ) in patients with amyloidosis: a first US report. 淀粉样变性患者冠状动脉造影衍生微血管评估（IMRangio）：美国首份报告。

IF 1.5 4区医学

Coronary artery disease Pub Date : 2024-12-01 Epub Date: 2024-09-27 DOI: 10.1097/MCA.0000000000001426

Edward T Ha, Kumudha Ramasubbu, Shudhanshu Alishetti, Marline Attallah, Manish A Parikh, Yuhei Kobayashi

引用次数: 0