Coronary artery diseasePub Date : 2025-11-01Epub Date: 2025-09-24DOI: 10.1097/MCA.0000000000001528
Yanbing Jiang, Li Xie, Lorenzo Azzalinilini, Xiaohui Zhao
{"title":"Optical coherence tomography assessment of retrograde wire in chronic total occlusion percutaneous coronary intervention.","authors":"Yanbing Jiang, Li Xie, Lorenzo Azzalinilini, Xiaohui Zhao","doi":"10.1097/MCA.0000000000001528","DOIUrl":"10.1097/MCA.0000000000001528","url":null,"abstract":"","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":"622-623"},"PeriodicalIF":2.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143981515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Safety and efficacy of drug-eluting stent combined with drug-coated balloon in the treatment of complex coronary artery lesions.","authors":"Xiaotao Li, Yuhong Yang, Ran Zhang, Dawei Yang, Xiaojie Chen, Jia Wang, Chenhao Zhang","doi":"10.1097/MCA.0000000000001543","DOIUrl":"10.1097/MCA.0000000000001543","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to explore the safety and efficacy of drug-eluting stents (DES) combined with drug-coated balloons (DCB) in the treatment of complex coronary artery lesions.</p><p><strong>Methods: </strong>In total, 305 patients with complex coronary artery lesions who underwent percutaneous coronary intervention were retrospectively included in this study. The patients were divided into the DES combined with the DCB treatment group (hybrid group) and the DES-only treatment group (DES group), and the target lesion revascularization (TLR) and major adverse cardiovascular events (MACE) were compared between the two groups during 2-year follow-up.</p><p><strong>Results: </strong>There were no significant differences between the two groups in baseline clinical characteristics ( P > 0.05). In the treated lesions of reference vessel diameters (RVD) ≥3 mm, there were no significant differences in coronary angiography and interventional characteristics between the two groups. In the treated lesion of RVD <3mm, the hybrid group had a higher proportion of lesion preparation ( P <0.001) and a higher rate of residual stenosis ( P <0.001) than the DES group. During the 2-year follow-up, the clinical outcomes between the two groups showed no significant differences. After propensity score matching, there were still no significant differences between the two groups in the cumulative survival rates without TLR (95.8% vs. 94.2%; log-rank P = 0.560) or MACE (89.4% vs. 87.8%; log-rank P = 0.578) at 2-year follow-up.</p><p><strong>Conclusion: </strong>During the 2-year follow-up, DES combined with DCB treatment showed similar efficacy and safety compared with DES-only treatment in complex coronary artery lesions.</p>","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":"587-594"},"PeriodicalIF":2.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Coronary artery diseasePub Date : 2025-11-01Epub Date: 2025-09-24DOI: 10.1097/MCA.0000000000001540
Muhammad Saad, Ifrah Ansari, Muhammad Umer Sohail, Syed Ibad Ahsan, Saad Ahmed Waqas, Muhammad Sameer Arshad
{"title":"Rising burden of coronary artery disease-related mortality among USA adults with atrial fibrillation from 1999 to 2020.","authors":"Muhammad Saad, Ifrah Ansari, Muhammad Umer Sohail, Syed Ibad Ahsan, Saad Ahmed Waqas, Muhammad Sameer Arshad","doi":"10.1097/MCA.0000000000001540","DOIUrl":"10.1097/MCA.0000000000001540","url":null,"abstract":"<p><strong>Background: </strong>Coronary artery disease (CAD) and atrial fibrillation (AF) are significant cardiovascular conditions with substantial health and economic burdens. Despite advancements in treatment, long-term mortality trends among individuals with both conditions remain underexplored. This study investigates age-adjusted mortality rates (AAMRs) from 1999 to 2020 and examines trends to address these gaps and highlight demographic and geographic disparities.</p><p><strong>Methods: </strong>Mortality data from the Centers for Disease Control and Prevention's Wide-Ranging Online Data for Epidemiologic Research database were analyzed for cases where CAD (ICD-10 codes I20-I25) and AF (ICD-10 code I48) were either contributing or underlying causes of death. Individuals aged 25 years and older were included in the analysis. AAMRs were calculated using direct standardization to the 2000 USA population, and trends were assessed using Joinpoint regression analysis. Mortality trends were stratified by sex, race, geography, and urbanization to identify disparities.</p><p><strong>Results: </strong>Between 1999 and 2020, AAMRs for CAD- and AF-related mortality increased from 14.4 to 23.4 per 100 000, with an average annual percent change of +2.2% (95% confidence interval: 2.0-2.4). Men consistently exhibited higher overall AAMRs than women (22.9 vs. 13.1 ). Non-Hispanic (NH) White individuals had the highest AAMR (18.6), followed by NH American Indians (12.3), NH Blacks (10.0), Hispanics (9.4), and NH Asians (8.0). Rural areas experienced significantly higher AAMRs than urban areas (19.2 vs. 16.6). AAMRs were disproportionately higher in Western (17.7) and Midwestern USA regions (17.7). States in the top 90 th percentile reported nearly double the AAMRs compared to those in the bottom 10 th percentile.</p><p><strong>Conclusion: </strong>Mortality rates associated with coexisting CAD and AF have significantly increased, with the most pronounced rise occurring after 2018. The findings reveal substantial disparities across sex, race, and geography. Targeted interventions are essential to address these inequalities, improve health outcomes, and reduce the growing burden of CAD and AF-related mortality.</p>","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":"595-603"},"PeriodicalIF":2.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144246862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Coronary artery diseasePub Date : 2025-11-01Epub Date: 2025-09-24DOI: 10.1097/MCA.0000000000001533
Aiza Ahsan, Hafsah Mehmood, Zainab Ali Siddiqui, Raveen Mujeeb
{"title":"The dual burden of iron and vitamin D deficiencies in the growing epidemic of coronary heart disease across Asia: a call to action.","authors":"Aiza Ahsan, Hafsah Mehmood, Zainab Ali Siddiqui, Raveen Mujeeb","doi":"10.1097/MCA.0000000000001533","DOIUrl":"https://doi.org/10.1097/MCA.0000000000001533","url":null,"abstract":"","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":"36 7","pages":"633-634"},"PeriodicalIF":2.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145136202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Coronary artery diseasePub Date : 2025-11-01Epub Date: 2025-04-01DOI: 10.1097/MCA.0000000000001526
Minggang Zhou, Li Chen
{"title":"Spontaneous formation of an arteriovenous fistula: an unusual decompression pathway for septal collateral perforation and hematoma.","authors":"Minggang Zhou, Li Chen","doi":"10.1097/MCA.0000000000001526","DOIUrl":"10.1097/MCA.0000000000001526","url":null,"abstract":"","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":"620-621"},"PeriodicalIF":2.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143751508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Coronary artery diseasePub Date : 2025-11-01Epub Date: 2025-04-04DOI: 10.1097/MCA.0000000000001525
Ilke Erbay, Pelin Aladag, Naile Eris Gudul, Ugur Kokturk, Melisa Begum Kisa, Ahmet Avci
{"title":"Enhancing the diagnostic specificity of exercise ECG testing in obstructive coronary artery disease: the role of the Selvester QRS score.","authors":"Ilke Erbay, Pelin Aladag, Naile Eris Gudul, Ugur Kokturk, Melisa Begum Kisa, Ahmet Avci","doi":"10.1097/MCA.0000000000001525","DOIUrl":"10.1097/MCA.0000000000001525","url":null,"abstract":"<p><strong>Background: </strong>Exercise ECG testing is a widely used, noninvasive tool for detecting obstructive coronary artery disease (OCAD). However, its diagnostic performance is often limited by low specificity, leading to false-positive results and unnecessary invasive procedures.</p><p><strong>Objective: </strong>This study aims to assess the potential of combining the Selvester QRS score with exercise ECG to enhance diagnostic specificity for OCAD in patients with suspected stable angina.</p><p><strong>Methods: </strong>This retrospective study included 203 patients who presented with chest pain, underwent exercise ECG and were assessed for OCAD by coronary angiography or computed tomography angiography. Receiver operating characteristic analysis identified the optimal Selvester QRS score cutoff and assessed the diagnostic performance of exercise ECG and the combined model. Multivariable logistic regression was performed in the exercise ECG positive and negative groups.</p><p><strong>Results: </strong>Of the 203 patients, 116 were diagnosed with OCAD. The optimal Selvester QRS score cutoff was ≥3, with a sensitivity of 83.6% and a specificity of 93.1%. The combination of a positive exercise ECG and a Selvester QRS score ≥3 achieved the highest specificity (98.9%). Regression analyses showed that Selvester QRS score ≥3 was an independent predictor of OCAD, even in patients with negative exercise ECG results (adjusted odds ratio: 7.018; P < 0.001).</p><p><strong>Conclusion: </strong>The Selvester QRS score can improve the specificity of the exercise ECG in detecting OCAD in patients with suspected stable angina. This approach has the potential to reduce false positives and unnecessary invasive procedures by improving risk stratification.</p>","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":"545-553"},"PeriodicalIF":2.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143771704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Coronary artery diseasePub Date : 2025-11-01Epub Date: 2025-06-17DOI: 10.1097/MCA.0000000000001539
Ingela Khan, Caroline A B Hondros, Silja Hanseth, Eva R Pedersen, Siren Hovland, Terje H Larsen, Mai Tone Lønnebakken
{"title":"Epicardial adipose tissue volume, compositional plaque progression, and vulnerability in nonobstructive coronary artery disease.","authors":"Ingela Khan, Caroline A B Hondros, Silja Hanseth, Eva R Pedersen, Siren Hovland, Terje H Larsen, Mai Tone Lønnebakken","doi":"10.1097/MCA.0000000000001539","DOIUrl":"10.1097/MCA.0000000000001539","url":null,"abstract":"<p><strong>Background: </strong>Inflammation is a driver of atherosclerosis and plaque vulnerability. Epicardial adipose tissue (EAT) accumulation is associated with inflammation. The aim of this study was, therefore, to explore the association between EAT volume, compositional plaque progression, and vulnerability in nonobstructive coronary artery disease (CAD).</p><p><strong>Methods: </strong>We identified 31 individuals [median age 58 (52, 68) years, 42% women] from the Norwegian Registry of Invasive Cardiology with nonobstructive CAD undergoing clinically indicated serial cardiac computed tomography (CT) and coronary CT angiography (CCTA). EAT volume was measured at baseline by a semiautomatic analysis software. Patients were grouped according to lower or higher than median baseline EAT (b-EAT) volume. Plaque progression was quantified by CCTA as annual change in total and compositional plaque volume. Hypodense plaques were adjudicated as vulnerable plaques.</p><p><strong>Results: </strong>Patients with high b-EAT volume had numerically lower calcium score, coronary artery segment involvement score, total coronary plaque burden, and increased prevalence of vulnerable plaques compared with patients with low EAT volume at baseline and follow-up, even if it did not reach statistical significance. Compared with patients with low b-EAT volume, patients with high b-EAT volume tended to have an annual regression in total plaque volume, while the proportion of vulnerable hypodense plaque volume increased.</p><p><strong>Conclusion: </strong>In nonobstructive CAD, patients with high b-EAT volume tended to have a regression of total plaque volume, but a transformation into a vulnerable plaque phenotype during follow-up. Whether lifestyle changes may improve prognosis in nonobstructive CAD needs to be confirmed in larger trials.</p>","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":"580-586"},"PeriodicalIF":2.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144301284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}