Coronary artery disease最新文献

Burden and predictors of thirty-day readmission in patients with NSTEMI: a retrospective analysis of the 2020 NRD database. NSTEMI 患者三十天再入院的负担和预测因素：2020 年 NRD 数据库的回顾性分析。

IF 1.5 4区医学

Coronary artery disease Pub Date : 2025-01-01 Epub Date: 2024-08-28 DOI: 10.1097/MCA.0000000000001419

Anil Jha, Palak Patel, Anand M Krishnan, Akil A Sherif, Ajay K Mishra, Ahmed Mohamed, Umabalan Thirupathy, Pradnya B Bhattad, Mazen Roumia

{"title":"Burden and predictors of thirty-day readmission in patients with NSTEMI: a retrospective analysis of the 2020 NRD database.","authors":"Anil Jha, Palak Patel, Anand M Krishnan, Akil A Sherif, Ajay K Mishra, Ahmed Mohamed, Umabalan Thirupathy, Pradnya B Bhattad, Mazen Roumia","doi":"10.1097/MCA.0000000000001419","DOIUrl":"10.1097/MCA.0000000000001419","url":null,"abstract":"Background: Non-ST-segment elevation myocardial infarction (NSTEMI) is an entity which was defined as a type of a coronary syndrome with positive cardiac biomarker of myocardial necrosis with no ST-segment elevation in ECG. Currently, the centers for Medicare and Medicaid services (CMS) Hospital readmission reduction program assistance risk-adjusted 30-day readmission rates for five major clinical entities which includes acute myocardial infarction.Methods: We performed this retrospective study to look into the current burden and predictors of NSTEMI readmission. Data were obtained from the Nationwide Readmission Database for the year 2020. We analyzed data on hospital readmission of 336 620 adults who were admitted for NSTEMI.Results: The 30-day readmission rate was 13.5% with NSTEMI being the most common cause of readmission. Mortality was higher in readmitted patients compared to index admission (5.4 vs 3.6%, P = 0.000). Higher risk of readmission was associated with female sex, higher Charlson comorbidity index, and longer length of stay. Lower risk of admission was seen in patients from smaller communities, patients who underwent percutaneous coronary intervention, and discharged to rehabilitation facilities.Conclusion: Although we found an improvement in readmission rates compared to prior studies, about 13% of patients continue to get readmitted within 30 days causing significant cost to the healthcare system and often these patients have worse outcomes. We need continuing large-scale studies to identify quality measures to prevent readmission, improve mortality during readmission, and make better use of financial resources.","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":"45-50"},"PeriodicalIF":1.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142072236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Deep engagement, big trouble: a guide catheter induced aortocoronary dissection during percutaneous coronary intervention. 深度介入，大麻烦：经皮冠状动脉介入治疗过程中导引导管诱发主动脉夹层。

IF 1.5 4区医学

Coronary artery disease Pub Date : 2025-01-01 Epub Date: 2024-08-20 DOI: 10.1097/MCA.0000000000001416

Charalampos Kakderis, Matthaios Didagelos, Stella-Maria Angelopoulou, Antonios Kouparanis, Thomas Trantas Chrysochoidis, Konstantinos C Theodoropoulos, Antonios Ziakas

引用次数: 0

Vasospasm associated rapid plaque progression secondary to intraplaque hemorrhage.

IF 1.5 4区医学

Coronary artery disease Pub Date : 2025-01-01 Epub Date: 2024-12-04 DOI: 10.1097/MCA.0000000000001384

Alexander Marschall, Fernando Rivero, Teresa Bastante, David Del Val, Javier Cuesta, Fernando Alfonso

引用次数: 0

The effectiveness of HALP score in predicting mortality in non-ST-elevation myocardial infarction patients. HALP 评分预测非 ST 段抬高型心肌梗死患者死亡率的有效性。

IF 1.5 4区医学

Coronary artery disease Pub Date : 2025-01-01 Epub Date: 2024-12-04 DOI: 10.1097/MCA.0000000000001415

Raif Kiliç, Tuncay Güzel, Adem Aktan, Hamdullah Güzel, Ahmet Ferhat Kaya, Yusuf Çankaya

{"title":"The effectiveness of HALP score in predicting mortality in non-ST-elevation myocardial infarction patients.","authors":"Raif Kiliç, Tuncay Güzel, Adem Aktan, Hamdullah Güzel, Ahmet Ferhat Kaya, Yusuf Çankaya","doi":"10.1097/MCA.0000000000001415","DOIUrl":"10.1097/MCA.0000000000001415","url":null,"abstract":"Background: The HALP score, measured based on hemoglobin, albumin, lymphocyte, and platelet levels, is regarded as a novel scoring system that indicates the status of systemic inflammation and nutritional health. Our study aimed to evaluate the relationship between HALP score and prognosis in non-ST-elevation myocardial infarction (NSTEMI) patients.Methods: Between 1 January 2020 and 1 January 2022, 568 consecutive patients diagnosed with NSTEMI from a single center were included in the study retrospectively. The patients were divided into two equal groups according to the median HALP cutoff value of 44.05. Patients were followed for at least 1 year from the date of admission.Results: The average age of the patients was 62.3 ± 10.6 years and 43.7% were female. In-hospital and 1-year mortality were found to be significantly higher in the group with low HALP scores (6.0 vs. 2.1%, P = 0.019 and 22.5 vs. 9.9%, P < 0.001, respectively). In receiver operating characteristic curve analysis, a cutoff level of 34.6 of the HALP score predicted 1-year mortality with 71% sensitivity and 65% specificity (area under the curve: 0.707, 95% confidence interval: 0.651-0.762, P < 0.001). In Kaplan-Meier analysis, higher mortality rates were observed over time in the group with lower HALP scores (log-rank test=16.767, P < 0.001). In Cox regression analysis, the HALP score was found to be an independent predictor of 1-year mortality (odds ratio: 0.969, 95% confidence interval: 0.958-0.981, P < 0.001).Conclusion: We found that a low HALP score could predict in-hospital and 1-year mortality in patients admitted to the hospital with a diagnosis of NSTEMI.","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":"39-44"},"PeriodicalIF":1.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141859291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Temporal trends in the treatment and outcome of nonagenarians with acute coronary syndrome. 非老年急性冠状动脉综合征患者的治疗和预后的时间趋势。

IF 1.5 4区医学

Coronary artery disease Pub Date : 2025-01-01 Epub Date: 2024-09-27 DOI: 10.1097/MCA.0000000000001427

Ilya Losin, Ela Giladi, Ziad Arow, Ranin Hilu, Tal Ovdat, Abid Assali, David Pereg

{"title":"Temporal trends in the treatment and outcome of nonagenarians with acute coronary syndrome.","authors":"Ilya Losin, Ela Giladi, Ziad Arow, Ranin Hilu, Tal Ovdat, Abid Assali, David Pereg","doi":"10.1097/MCA.0000000000001427","DOIUrl":"10.1097/MCA.0000000000001427","url":null,"abstract":"Background: Nonagenarians are a fast-growing age group among acute coronary syndrome (ACS) patients. While new therapeutic options have improved outcomes of ACS patients, data regarding very elderly ACS patients are limited. We aimed to evaluate temporal trends in the treatment and outcomes of nonagenarian ACS patients.Methods: Included were ACS patients aged below 90 years enrolled in ACS Israeli Survey. Patients were divided into two groups according to enrolment period: early (2000-2010) and recent (2012-2021). The primary endpoints were 30-day major adverse cardiovascular events and all-cause mortality. Secondary outcomes included in-hospital and 1-year all-cause mortality.Results: Included were 316 elderly ACS patients. Of them, 184 were enrolled in the early and 132 in recent surveys. Patients enrolled in the recent period were more commonly referred for an invasive strategy and more commonly received guideline-based medical therapy. All-cause mortality at 30 days was significantly lower in the recent group compared with the early group (12.5 and 26.1%, respectively, P = 0.005). Rates of 30-day major adverse cardiovascular events were also significantly lower in the recent group (21.9 and 35.9%, respectively, P = 0.012). Patients in the recent group received more aggressive medical therapy in discharge but at 30-day follow-up, no difference in medical treatment was observed in the two groups. There were no significant differences in 1-year mortality rates.Conclusions: Treatment of nonagenarians with ACS has improved over the past decade. Treatment improvement was associated with a significant improvement in 30-day outcomes without any effect in 1 year. Nevertheless, even with contemporary treatment, nonagenarians with ACS remain a high-risk group with high mortality rates.","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":"65-69"},"PeriodicalIF":1.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142343088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Successful stent-less treatment of acute myocardial infarction using an excimer laser combined with long inflation using perfusion balloon: Findings of optical frequency domain imaging.

IF 1.5 4区医学

Coronary artery disease Pub Date : 2025-01-01 Epub Date: 2024-12-04 DOI: 10.1097/MCA.0000000000001388

Naoki Shibata, Kensuke Takagi, Yasuhiro Morita, Itsuro Morishima

引用次数: 0

Impact of serum cholinesterase on calcified nodules in patients with stable coronary artery disease. 血清胆碱酯酶对稳定型冠心病患者钙化结节的影响

IF 1.5 4区医学

Coronary artery disease Pub Date : 2025-01-01 Epub Date: 2024-10-01 DOI: 10.1097/MCA.0000000000001428

Daisuke Kanda, Akihiro Tokushige, Kenta Ohmure, Hirokazu Shimono, Hiroyuki Tabata, Nobuhiro Ito, Takuro Kubozono, Mitsuru Ohishi

{"title":"Impact of serum cholinesterase on calcified nodules in patients with stable coronary artery disease.","authors":"Daisuke Kanda, Akihiro Tokushige, Kenta Ohmure, Hirokazu Shimono, Hiroyuki Tabata, Nobuhiro Ito, Takuro Kubozono, Mitsuru Ohishi","doi":"10.1097/MCA.0000000000001428","DOIUrl":"10.1097/MCA.0000000000001428","url":null,"abstract":"Background: Calcified nodules (CNs) are an advanced stage of coronary calcification that can have significant clinical implications. We investigated factors associated with CNs, the etiology of which is not fully understood.Methods: We retrospectively evaluated 619 patients with stable coronary artery disease who underwent intravascular ultrasound (IVUS)-guided percutaneous coronary intervention (PCI). CNs in the culprit lesion were evaluated via IVUS, and all-cause mortality and major cardiovascular and cerebrovascular events (MACCEs) were compared between the CN and non-CN groups.Results: The CN group ( n = 40 patients) had a significantly lower survival rate and a higher incidence of MACCE than the non-CN group ( P = 0.020 and P < 0.001, respectively). Multivariate logistic regression analysis models revealed that chronic kidney disease and serum cholinesterase (ChE) level were associated with CN formation [odds ratio (OR): 3.15, 95% confidence interval (CI): 1.30-7.69, P = 0.001 and OR: 0.94, 95% CI: 0.88-0.99, P = 0.042]. The optimal cutoff of serum ChE level as per the receiver operating characteristic curve was 309 units/l (Area under the curve = 0.67, sensitivity = 93%, specificity = 40%, P = 0.001). The low-ChE group divided according to the optimal cutoff value showed significantly higher cumulative incidence of MACCEs after PCI than the high-ChE group as per Kaplan-Meier analysis.Conclusion: The presence of CNs is significantly associated with a poor prognosis and MACCE after PCI among patients with stable coronary artery disease. Serum ChE levels may affect CN formation.","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":"70-77"},"PeriodicalIF":1.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11617076/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142380238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lipid-lowering therapy after acute coronary syndromes: a multinational European survey. 急性冠状动脉综合征后的降脂治疗：一项欧洲多国调查。

IF 1.5 4区医学

Coronary artery disease Pub Date : 2025-01-01 Epub Date: 2024-09-12 DOI: 10.1097/MCA.0000000000001420

Gal Tsaban, Rafael Vidal Perez, Konstantin A Krychtiuk, Ingo Ahrens, Sigrun Halvorsen, Christian Hassager, Kurt Huber, Francois Schiele, Alessandro Sionis, Marc J Claeys

{"title":"Lipid-lowering therapy after acute coronary syndromes: a multinational European survey.","authors":"Gal Tsaban, Rafael Vidal Perez, Konstantin A Krychtiuk, Ingo Ahrens, Sigrun Halvorsen, Christian Hassager, Kurt Huber, Francois Schiele, Alessandro Sionis, Marc J Claeys","doi":"10.1097/MCA.0000000000001420","DOIUrl":"10.1097/MCA.0000000000001420","url":null,"abstract":"Background: Recent guidelines on acute coronary syndromes (ACS) recommend initiating lipid-lowering therapy (LLT) as early as possible to obtain >50% low-density-lipoprotein cholesterol (LDL-c) reduction and an LDL-c < 1.4 mmol/l.Methods: A multinational European survey study of ACS patients between 2021-2022 and acquired data on LLT and lipid levels on admission and during 1-year posthospitalization. We compared plasma lipid changes and adherence to post-ACS lipid targets across two in-hospital LLT groups: high-intensity statin (HIS) monotherapy (mono-HIS) and a combination of HIS and ezetimibe (combo-HIS).Results: Of 286 patients, 268 (94%) received in-hospital HIS and were included in the final analysis. Patients (median age: 61.1 years) had a median baseline LDL-c of 3.3 mmol/l. Mono-HIS was the predominant in-hospital LLT (72.4%). In-hospital combo-HIS was administered in 27.6% of the cases. Patients from high-income countries ( n = 141) were more likely to receive in-hospital combo-HIS than patients from middle-income countries [ n = 127; 38.3% vs. 15.7% patients, P < 0.001). One-year post-ACS, 50 (26.5%) patients from the mono-HIS group received ezetimibe. The target of LDL-c ≤ 55 mg/dl was reached in 85 patients (31.7%), without significant difference between study groups [mono-HIS: 56 (28.9%) and combo-HIS: 29 (39.2%) patients, P = 0.10]. The target of >50% reduction was achieved more frequently among the combo-HIS group than in the mono-HIS group (50.0% vs. 29.9%, respectively, P = 0.002).Conclusion: LDL-c targets were achieved in less than half of the patients post-ACS, regardless of the LLT regimen. Combo-HIS was initiated in-hospital post-ACS in only 28% and was associated with greater LDL-c reduction compared to a staged approach of mono-HIS with up-titration at follow-up.","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":"51-58"},"PeriodicalIF":1.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142281587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Trend and outcomes of aspiration thrombectomy use in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention: an analysis of the National Inpatient Sample. 接受初级经皮冠状动脉介入治疗的 ST 段抬高型心肌梗死患者使用抽吸血栓切除术的趋势和结果：全国住院患者样本分析。

IF 1.5 4区医学

Coronary artery disease Pub Date : 2025-01-01 Epub Date: 2024-10-09 DOI: 10.1097/MCA.0000000000001429

Ankur Sethi, Emily Hiltner, Marc Sandhaus, Delphine Tang, Ashish Awasthi

引用次数: 0

Distal versus traditional radial access in patients undergoing emergency coronary angiography or percutaneous coronary intervention: a systematic review and meta-analysis. 在接受急诊冠状动脉造影术或经皮冠状动脉介入治疗的患者中，远端桡动脉入路与传统桡动脉入路的比较：系统回顾和荟萃分析。

IF 1.5 4区医学

Coronary artery disease Pub Date : 2025-01-01 Epub Date: 2024-07-30 DOI: 10.1097/MCA.0000000000001411

Vinicius Bittar, Thierry Trevisan, Mariana R C Clemente, Guilherme Pontes, Nicole Felix, Wilton F Gomes

{"title":"Distal versus traditional radial access in patients undergoing emergency coronary angiography or percutaneous coronary intervention: a systematic review and meta-analysis.","authors":"Vinicius Bittar, Thierry Trevisan, Mariana R C Clemente, Guilherme Pontes, Nicole Felix, Wilton F Gomes","doi":"10.1097/MCA.0000000000001411","DOIUrl":"10.1097/MCA.0000000000001411","url":null,"abstract":"Background: Distal radial access (DRA) is a well-tolerated and effective alternative to traditional radial access (TRA) for coronary procedures. However, the comparative value of these modalities remains unknown in the emergency setting, particularly in patients with ST-elevation myocardial infarction (STEMI).Objective: To compare DRA versus TRA for emergency coronary procedures through a meta-analysis.Methods: We systematically searched PubMed , Embase , and Cochrane databases to identify studies comparing DRA versus TRA in patients undergoing emergency coronary angiography (CAG) or percutaneous coronary intervention (PCI). All statistical analyses were performed using R software version 4.3.1 with a random-effects model.Results: We included four studies comprising 543 patients undergoing emergency CAG or PCI, of whom 447 (82.3%) had STEMI. As compared with TRA, DRA was associated with lower radial artery occlusion rates (RR, 0.21; 95% CI, 0.06-0.72) and shorter hemostasis time (MD, -4.23 h; 95% CI, -6.23 to 2.13). There was no significant difference between modalities in terms of puncture failure (RR, 1.38; 95% CI, 0.31-6.19), crossover access (RR, 1.37; 95% CI, 0.42-4.44), puncture time (SMD, 0.33; 95% CI, -0.16 to 0.81), procedure time (MD, 0.97 min; 95% CI, -5.19 to 7.13), or rates of cannulation success (RR, 0.94; 95% CI, 0.83-1.06). In terms of other periprocedural complications, there were no differences between both groups. These findings remained consistent in a subgroup analysis of patients with STEMI.Conclusion: In this meta-analysis, DRA was superior to TRA in terms of radial artery occlusion and hemostasis time, with similar rates of periprocedural complications.","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":"18-27"},"PeriodicalIF":1.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141854961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0