Coronary artery disease最新文献_第10页

Evaluation of the relationship between carotid artery stenosis and CALLY index in patients undergoing isolated coronary artery bypass surgery. 评价孤立冠状动脉搭桥术患者颈动脉狭窄与CALLY指数的关系。

IF 2 4区医学

Coronary artery disease Pub Date : 2025-07-31 DOI: 10.1097/MCA.0000000000001558

Cihan Yücel, Serkan Ketenciler, Yaşar Gökkurt, İlhan Ozgol, İkra Gol, Mehmet Ali Yesiltas

{"title":"Evaluation of the relationship between carotid artery stenosis and CALLY index in patients undergoing isolated coronary artery bypass surgery.","authors":"Cihan Yücel, Serkan Ketenciler, Yaşar Gökkurt, İlhan Ozgol, İkra Gol, Mehmet Ali Yesiltas","doi":"10.1097/MCA.0000000000001558","DOIUrl":"https://doi.org/10.1097/MCA.0000000000001558","url":null,"abstract":"Background: Carotid artery stenosis is a significant predictor of perioperative stroke risk in patients undergoing coronary artery bypass grafting (CABG). Identifying noninvasive, simple, and clinically relevant biomarkers for risk stratification is crucial in this population. The CALLY index, a composite marker reflecting systemic inflammation and nutritional status, has shown prognostic value in various diseases. However, its relationship with carotid artery stenosis in patients undergoing isolated CABG remains unclear. This study aimed to evaluate the relationship between carotid artery stenosis and the CALLY index in patients undergoing isolated CABG.Methods: This retrospective, single-center study included 820 patients who underwent isolated CABG and preoperative carotid Doppler ultrasonography between January 2020 and December 2024. The degree of carotid artery stenosis was classified into three groups (<50, 50-70, >70%). CALLY index values were calculated using lymphocyte count, albumin, and C-reactive protein (CRP) levels. Statistical analyses included Kruskal-Wallis H and Spearman's rank correlation tests.Results: The CALLY index was significantly lower in patients with higher degrees of carotid artery stenosis (P < 0.001). A strong negative correlation was found between the CALLY index and carotid stenosis severity (Spearman's rho = -0.831, P < 0.001).Conclusion: Low CALLY index values are significantly associated with the presence and severity of carotid artery stenosis in patients undergoing isolated CABG. The CALLY index may serve as a simple and practical biomarker for preoperative risk assessment, aiding in the identification of high-risk patients and potentially improving surgical outcomes.","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144741429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-term observation of refractory coronary spastic angina assessed using serial acetylcholine provocation tests under medication: a case report. 长期观察难治性冠状动脉痉挛心绞痛在药物下使用系列乙酰胆碱激发试验评估：1例报告。

IF 2 4区医学

Coronary artery disease Pub Date : 2025-07-28 DOI: 10.1097/MCA.0000000000001559

Koichi Nakamura, Osamu Kurihara, Nobuaki Kobayashi, Daisuke Murakami, Masamichi Takano, Kuniya Asai

引用次数: 0

Sophoricoside enhances reparative macrophage polarization to promote cardiac repair postmyocardial infarction through PPAR-γ. 苦参皂苷通过PPAR-γ增强修复性巨噬细胞极化促进心肌梗死后心脏修复。

IF 1.5 4区医学

Coronary artery disease Pub Date : 2025-07-21 DOI: 10.1097/MCA.0000000000001554

Zhuo Jing Xu, Si Yang Hao

{"title":"Sophoricoside enhances reparative macrophage polarization to promote cardiac repair postmyocardial infarction through PPAR-γ.","authors":"Zhuo Jing Xu, Si Yang Hao","doi":"10.1097/MCA.0000000000001554","DOIUrl":"https://doi.org/10.1097/MCA.0000000000001554","url":null,"abstract":"Background: Myocardial infarction (MI) represents a significant cardiovascular condition that endangers human health. This research aimed to explore the therapeutic effectiveness of sophoricoside (Sop) using a mouse model of MI.Methods: To conduct this investigation, a mice model of MI was utilized, and Sop was delivered through oral administration via gavage. The area of MI in mice was assessed by Masson trichrome staining. Cardiac systolic function and left ventricular dilatation were measured by cardiac ultrasound. Picrosirius red staining and Masson's trichrome staining were performed to detect the collagen deposition and fibrosis. The expressions of reparative macrophage-associated markers were measured by quantitative real-time PCR. Western blotting was utilized to sense expression of lysyl oxidase (LOX), peroxisome proliferator-activated receptor γ (PPAR-γ), and collagen 1. Flow cytometry was performed to detect the number of macrophages. The Cell Counting Kit-8 assay was performed to detect Sop's cytotoxicity. The M2 polarization and efferocytosis in mice model of MI was verified by immunofluorescence assay.Results: Sop significantly reduced myocardial infarct size. Cardiac ultrasound evaluation further showed that Sop was effective in improving cardiac systolic dysfunction and left ventricular dilatation. In addition, Sop significantly promoted efferocytosis and reparative M2 macrophage polarization and inhibited glycolytic metabolic pathways, thereby promoting cardiac tissue repair. It was further found that Sop could obviously promote expression of PPAR-γ in the nucleus. GW9662 partially reversed the improvement of Sop on cardiac repair and reparative macrophage polarization in MI mice.Conclusion: In summary, this study elucidates that Sop enhances reparative macrophage polarization to promote cardiac repair post-MI through PPAR-γ.","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144674045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The impact of intravascular imaging on percutaneous coronary intervention outcomes in acute myocardial infarction: a systematic review and meta-analysis. 血管内成像对急性心肌梗死经皮冠状动脉介入治疗结果的影响：一项系统回顾和荟萃分析。

IF 2 4区医学

Coronary artery disease Pub Date : 2025-07-18 DOI: 10.1097/MCA.0000000000001553

Akshay Machanahalli Balakrishna, Dua Noor Butt, Alexander G Hall, Danielle B Dilsaver, Elissa S Altin, Srihari S Naidu, Jennifer A Rymer, Andrew M Goldsweig

{"title":"The impact of intravascular imaging on percutaneous coronary intervention outcomes in acute myocardial infarction: a systematic review and meta-analysis.","authors":"Akshay Machanahalli Balakrishna, Dua Noor Butt, Alexander G Hall, Danielle B Dilsaver, Elissa S Altin, Srihari S Naidu, Jennifer A Rymer, Andrew M Goldsweig","doi":"10.1097/MCA.0000000000001553","DOIUrl":"10.1097/MCA.0000000000001553","url":null,"abstract":"Background: Intravascular imaging (IVI) facilitates optimal outcomes in percutaneous coronary intervention (PCI). Focused data on the impact of IVI on outcomes of PCI in acute myocardial infarction (AMI), in particular, are scarce.Methods: A systematic search of the PubMed, EMBASE, Medline, and Cochrane databases was conducted from their inception to 1 December 2024 for studies comparing IVI to coronary angiography alone to guide PCI in AMI. Outcomes of interest included all-cause mortality (primary), cardiac mortality, major adverse cardiovascular events (MACE), recurrent myocardial infarction, target vessel revascularization (TVR), stent thrombosis, and target lesion revascularization (TLR). Random effects models were used to calculate relative risks (RRs) with 95% confidence intervals (CIs).Results: Fourteen studies (43 547 patients) met inclusion criteria; nine studies reported all-cause mortality. Among patients with AMI, compared with coronary angiography alone, patients with IVI-guided PCI had lower all-cause mortality (RR: 0.76, 95% CI: 0.64-0.89; P < 0.01). IVI had less cardiac death (RR: 0.71, 95% CI: 0.59-0.86; P < 0.01), MACE (RR: 0.85, 95% CI: 0.77-0.94; P < 0.01), recurrent MI (RR: 0.84, 95% CI: 0.71-99; P = 0.04), TVR (RR: 0.79, 95% CI: 0.70-0.89; P < 0.01), and stent thrombosis (RR: 0.69, 95% CI: 0.53-0.90; P = 0.01). TLR was not significantly different between IVI and coronary angiography alone.Conclusion: Among patients with AMI, IVI-guided PCI is associated with improved clinical outcomes compared with coronary angiography alone. Further high-quality randomized trials are needed to clarify the magnitude of benefit.","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144882380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ticagrelor and sleep apnea: an international retrospective cohort study. 替格瑞洛与睡眠呼吸暂停：一项国际回顾性队列研究

IF 2 4区医学

Coronary artery disease Pub Date : 2025-07-18 DOI: 10.1097/MCA.0000000000001556

Ramzi Ibrahim, Mahmoud Abdelnabi, Mohamed Allam, Eiad Habib, Hoang Nhat Pham, Rahmeh Alasmar, Hashim Alhammouri, Chadi Ayoub, Eric Yang, John Sweeney, Kwan Lee, Dan Sorajja, David Fortuin, Reza Arsanjani

引用次数: 0

Left main coronary artery 'pseudo bridging' on angiogram: a rare angiographic entity. 冠状动脉左主干血管造影显示“假桥”：一种罕见的血管造影现象。

IF 1.5 4区医学

Coronary artery disease Pub Date : 2025-07-16 DOI: 10.1097/MCA.0000000000001549

Pradnya Brijmohan Bhattad, Thomas C Piemonte

引用次数: 0

Trends and disparities in ischemic heart disease mortality in the United States: an analysis of CDC WONDER database, 1999-2020. 美国缺血性心脏病死亡率的趋势和差异：1999-2020年CDC WONDER数据库分析

IF 1.5 4区医学

Coronary artery disease Pub Date : 2025-07-07 DOI: 10.1097/MCA.0000000000001550

Muhammad Abdullah Naveed, Faizan Ahmed, Sherif Eltawansy, Ahila Ali, Zaima Afzaal, Bazil Azeem, Muhammad Kashan, Kainat Aman, Mushood Ahmed, Hritvik Jain, Omar Kamil, Faseeh Haider, Rabia Iqbal, Aman Ullah, Nisar Asmi, Muhammad Faizan Ali

{"title":"Trends and disparities in ischemic heart disease mortality in the United States: an analysis of CDC WONDER database, 1999-2020.","authors":"Muhammad Abdullah Naveed, Faizan Ahmed, Sherif Eltawansy, Ahila Ali, Zaima Afzaal, Bazil Azeem, Muhammad Kashan, Kainat Aman, Mushood Ahmed, Hritvik Jain, Omar Kamil, Faseeh Haider, Rabia Iqbal, Aman Ullah, Nisar Asmi, Muhammad Faizan Ali","doi":"10.1097/MCA.0000000000001550","DOIUrl":"https://doi.org/10.1097/MCA.0000000000001550","url":null,"abstract":"Background: Ischemic heart disease (IHD) remains a leading cause of mortality globally and has a high prevalence in the USA, necessitating an understanding of long-term trends to inform interventions. Considering demographic and geographic disparities, this study examines IHD-related mortality trends among US adults from 1999 to 2020.Aim: This study aimed to evaluate patterns and geographical variations in mortality associated with IHD among adults in the USA.Methods: Death certificates from the CDC WONDER database spanning from 1999 to 2020 were analyzed to investigate mortality related to IHD among adults aged 35 years and above. Age-adjusted mortality rates (AAMRs) per 100 000 persons and annual percent change were calculated and stratified by year, sex, race/ethnicity, and geographic region.Results: IHD caused 12 756 359 deaths among U.S. adults aged 35 and above from 1999 to 2020. Annual trends in AAMRs declined from 48.7 in 1999 to 28.9 in 2020, with notable fluctuations. Men consistently had higher AAMRs than women. Non-Hispanic Black or African American individuals exhibited the highest AAMRs. Geographically, significant disparities existed among states and regions, with the Northeast having the highest mortality. Nonmetropolitan areas consistently had higher AAMRs than metropolitan areas, showing varying trends over the study period.Conclusion: Fluctuations in mortality trends among IHD patients were observed over the study duration, revealing significant disparities across demographic and geographic parameters. Targeted interventions are imperative to alleviate the burden of IHD and mitigate mortality rates in the USA.","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144599627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between pulse wave velocity and coronary atherosclerosis. 脉搏波速度与冠状动脉粥样硬化的关系。

IF 1.5 4区医学

Coronary artery disease Pub Date : 2025-06-24 DOI: 10.1097/MCA.0000000000001548

Anshul Saxena, Muni Rubens, Shozab S Ali, Javier Jimenez, Juan Ruiz-Pelaez, Lara Arias, Raul Herrera, Theodore Feldman, Ricardo C Cury, Harneet K Walia, Sadeer Al-Kindi, Khurram Nasir, Jonathan A Fialkow, Sandra Chaparro

{"title":"Association between pulse wave velocity and coronary atherosclerosis.","authors":"Anshul Saxena, Muni Rubens, Shozab S Ali, Javier Jimenez, Juan Ruiz-Pelaez, Lara Arias, Raul Herrera, Theodore Feldman, Ricardo C Cury, Harneet K Walia, Sadeer Al-Kindi, Khurram Nasir, Jonathan A Fialkow, Sandra Chaparro","doi":"10.1097/MCA.0000000000001548","DOIUrl":"10.1097/MCA.0000000000001548","url":null,"abstract":"Background: Pulse wave velocity (PWV) is considered a more direct and accurate measure of arterial stiffness. This study explored the relationship between PWV and the presence and severity of coronary artery calcification (CAC) and coronary artery plaque (CAP).Methods: The current study was a cross-sectional analysis of data from the Miami Heart Study (MiHeart). The primary outcome variable of this study was the CAC score. The secondary outcome was the presence of CAC and CAP. Multivariable logistic regression and Bayesian linear regression were used to find the association between PWV CAC and CAP.Results: A total of 2359 participants were included in the study. The mean age (SD) of the sample was 53.4 (6.8) years and 50.4% were men. Multivariable logistic regression analysis showed that the odds of having CAC greater than 0 was significantly higher with increasing PWV [odds ratio (OR): 1.09, 95% confidence interval (CI): 1.01-1.18]. Similarly, multivariable logistic regression analysis also showed that the odds for CAP were significantly higher with increasing PWV (OR: 1.14, 95% CI: 1.06-1.23). The results of Bayesian linear regression analysis showed that there was a significant association between PWV and log CAC score.Conclusion: In a large sample of participants from the community and without a history of known cardiovascular disorder, we found that an increase in PWV was associated with the presence of CAC and CAP. In addition, we also found that PWV was associated with severity of CAC as well. Our findings show that PWV could be an important marker of subclinical coronary atherosclerosis in the general population.","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144368643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lessons learned from the first-in-man study of a novel everolimus-coated balloon for coronary in-stent restenosis. 新型依维莫司涂层球囊治疗冠状动脉支架内再狭窄的首次人体研究的经验教训。

IF 1.5 4区医学

Coronary artery disease Pub Date : 2025-06-17 DOI: 10.1097/MCA.0000000000001541

Rupak Desai, Nihar K Jena

引用次数: 0

Association between visceral fat metabolism score and atherosclerotic cardiovascular disease: evidence from NHANES 2005 to 2016. 内脏脂肪代谢评分与动脉粥样硬化性心血管疾病的相关性：来自NHANES 2005 - 2016的证据

IF 1.5 4区医学

Coronary artery disease Pub Date : 2025-06-17 DOI: 10.1097/MCA.0000000000001545

Songjie Wu, Sirui Jiang, Yefeng Yao, Mengying Li

{"title":"Association between visceral fat metabolism score and atherosclerotic cardiovascular disease: evidence from NHANES 2005 to 2016.","authors":"Songjie Wu, Sirui Jiang, Yefeng Yao, Mengying Li","doi":"10.1097/MCA.0000000000001545","DOIUrl":"https://doi.org/10.1097/MCA.0000000000001545","url":null,"abstract":"Background: Obesity and metabolic disorders are key contributors to the development of atherosclerotic cardiovascular disease (ASCVD). This study sought to investigate the relationship between the newly introduced Metabolic Score for Visceral Fat (METS-VF) and ASCVD, utilizing data from the National Health and Nutrition Examination Survey (NHANES).Methods: Data from NHANES 2005-2016 were analyzed. Adults with complete METS-VF and ASCVD data were included. Weighted multivariate logistic regression models assessed associations between METS-VF and ASCVD. Smoothed curve fitting and subgroup analyses further explored the relationship. Receiver operating characteristic curves were used to compare the predictive performance of METS-VF with other indicators of visceral fat.Results: A total of 9979 participants were included, among whom 807 had ASCVD. In the fully adjusted model, each 1-unit increase in METS-VF was associated with a 43% higher ASCVD risk (OR = 1.43, 95% CI: 1.11-1.85). Compared with Q1, the ORs for Q2, Q3, and Q4 were 1.71, 1.72, and 2.10, respectively (P for trend <0.05). The curve fitting showed a linear positive association. Subgroup analyses indicated significant associations in men, non-Hispanic Whites and Blacks, and participants without hypertension, who smoked, drank alcohol, or physically inactive. METS-VF showed better predictive ability (AUC = 0.734) than LAP, VAI, WC, and WHtR.Conclusions: METS-VF is a reliable, noninvasive, and cost-effective predictor of visceral obesity that demonstrates a linear positive correlation with ASCVD, supporting its use as an accurate measure of ASCVD risk.","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144301281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0