Muhammad Abdullah Naveed, Faizan Ahmed, Sherif Eltawansy, Ahila Ali, Zaima Afzaal, Bazil Azeem, Muhammad Kashan, Kainat Aman, Mushood Ahmed, Hritvik Jain, Omar Kamil, Faseeh Haider, Rabia Iqbal, Aman Ullah, Nisar Asmi, Muhammad Faizan Ali
{"title":"美国缺血性心脏病死亡率的趋势和差异:1999-2020年CDC WONDER数据库分析","authors":"Muhammad Abdullah Naveed, Faizan Ahmed, Sherif Eltawansy, Ahila Ali, Zaima Afzaal, Bazil Azeem, Muhammad Kashan, Kainat Aman, Mushood Ahmed, Hritvik Jain, Omar Kamil, Faseeh Haider, Rabia Iqbal, Aman Ullah, Nisar Asmi, Muhammad Faizan Ali","doi":"10.1097/MCA.0000000000001550","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Ischemic heart disease (IHD) remains a leading cause of mortality globally and has a high prevalence in the USA, necessitating an understanding of long-term trends to inform interventions. Considering demographic and geographic disparities, this study examines IHD-related mortality trends among US adults from 1999 to 2020.</p><p><strong>Aim: </strong>This study aimed to evaluate patterns and geographical variations in mortality associated with IHD among adults in the USA.</p><p><strong>Methods: </strong>Death certificates from the CDC WONDER database spanning from 1999 to 2020 were analyzed to investigate mortality related to IHD among adults aged 35 years and above. Age-adjusted mortality rates (AAMRs) per 100 000 persons and annual percent change were calculated and stratified by year, sex, race/ethnicity, and geographic region.</p><p><strong>Results: </strong>IHD caused 12 756 359 deaths among U.S. adults aged 35 and above from 1999 to 2020. Annual trends in AAMRs declined from 48.7 in 1999 to 28.9 in 2020, with notable fluctuations. Men consistently had higher AAMRs than women. Non-Hispanic Black or African American individuals exhibited the highest AAMRs. Geographically, significant disparities existed among states and regions, with the Northeast having the highest mortality. Nonmetropolitan areas consistently had higher AAMRs than metropolitan areas, showing varying trends over the study period.</p><p><strong>Conclusion: </strong>Fluctuations in mortality trends among IHD patients were observed over the study duration, revealing significant disparities across demographic and geographic parameters. Targeted interventions are imperative to alleviate the burden of IHD and mitigate mortality rates in the USA.</p>","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":""},"PeriodicalIF":1.5000,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Trends and disparities in ischemic heart disease mortality in the United States: an analysis of CDC WONDER database, 1999-2020.\",\"authors\":\"Muhammad Abdullah Naveed, Faizan Ahmed, Sherif Eltawansy, Ahila Ali, Zaima Afzaal, Bazil Azeem, Muhammad Kashan, Kainat Aman, Mushood Ahmed, Hritvik Jain, Omar Kamil, Faseeh Haider, Rabia Iqbal, Aman Ullah, Nisar Asmi, Muhammad Faizan Ali\",\"doi\":\"10.1097/MCA.0000000000001550\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Ischemic heart disease (IHD) remains a leading cause of mortality globally and has a high prevalence in the USA, necessitating an understanding of long-term trends to inform interventions. Considering demographic and geographic disparities, this study examines IHD-related mortality trends among US adults from 1999 to 2020.</p><p><strong>Aim: </strong>This study aimed to evaluate patterns and geographical variations in mortality associated with IHD among adults in the USA.</p><p><strong>Methods: </strong>Death certificates from the CDC WONDER database spanning from 1999 to 2020 were analyzed to investigate mortality related to IHD among adults aged 35 years and above. Age-adjusted mortality rates (AAMRs) per 100 000 persons and annual percent change were calculated and stratified by year, sex, race/ethnicity, and geographic region.</p><p><strong>Results: </strong>IHD caused 12 756 359 deaths among U.S. adults aged 35 and above from 1999 to 2020. Annual trends in AAMRs declined from 48.7 in 1999 to 28.9 in 2020, with notable fluctuations. Men consistently had higher AAMRs than women. Non-Hispanic Black or African American individuals exhibited the highest AAMRs. Geographically, significant disparities existed among states and regions, with the Northeast having the highest mortality. Nonmetropolitan areas consistently had higher AAMRs than metropolitan areas, showing varying trends over the study period.</p><p><strong>Conclusion: </strong>Fluctuations in mortality trends among IHD patients were observed over the study duration, revealing significant disparities across demographic and geographic parameters. Targeted interventions are imperative to alleviate the burden of IHD and mitigate mortality rates in the USA.</p>\",\"PeriodicalId\":10702,\"journal\":{\"name\":\"Coronary artery disease\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.5000,\"publicationDate\":\"2025-07-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Coronary artery disease\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1097/MCA.0000000000001550\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CARDIAC & CARDIOVASCULAR SYSTEMS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Coronary artery disease","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/MCA.0000000000001550","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
Trends and disparities in ischemic heart disease mortality in the United States: an analysis of CDC WONDER database, 1999-2020.
Background: Ischemic heart disease (IHD) remains a leading cause of mortality globally and has a high prevalence in the USA, necessitating an understanding of long-term trends to inform interventions. Considering demographic and geographic disparities, this study examines IHD-related mortality trends among US adults from 1999 to 2020.
Aim: This study aimed to evaluate patterns and geographical variations in mortality associated with IHD among adults in the USA.
Methods: Death certificates from the CDC WONDER database spanning from 1999 to 2020 were analyzed to investigate mortality related to IHD among adults aged 35 years and above. Age-adjusted mortality rates (AAMRs) per 100 000 persons and annual percent change were calculated and stratified by year, sex, race/ethnicity, and geographic region.
Results: IHD caused 12 756 359 deaths among U.S. adults aged 35 and above from 1999 to 2020. Annual trends in AAMRs declined from 48.7 in 1999 to 28.9 in 2020, with notable fluctuations. Men consistently had higher AAMRs than women. Non-Hispanic Black or African American individuals exhibited the highest AAMRs. Geographically, significant disparities existed among states and regions, with the Northeast having the highest mortality. Nonmetropolitan areas consistently had higher AAMRs than metropolitan areas, showing varying trends over the study period.
Conclusion: Fluctuations in mortality trends among IHD patients were observed over the study duration, revealing significant disparities across demographic and geographic parameters. Targeted interventions are imperative to alleviate the burden of IHD and mitigate mortality rates in the USA.
期刊介绍:
Coronary Artery Disease welcomes reports of original research with a clinical emphasis, including observational studies, clinical trials, translational research, novel imaging, pharmacology and interventional approaches as well as advances in laboratory research that contribute to the understanding of coronary artery disease. Each issue of Coronary Artery Disease is divided into four areas of focus: Original Research articles, Review in Depth articles by leading experts in the field, Editorials and Images in Coronary Artery Disease. The Editorials will comment on selected original research published in each issue of Coronary Artery Disease, as well as highlight controversies in coronary artery disease understanding and management.
Submitted artcles undergo a preliminary review by the editor. Some articles may be returned to authors without further consideration. Those being considered for publication will undergo further assessment and peer-review by the editors and those invited to do so from a reviewer pool.