Cihan Yücel, Serkan Ketenciler, Yaşar Gökkurt, İlhan Ozgol, İkra Gol, Mehmet Ali Yesiltas
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引用次数: 0
Abstract
Background: Carotid artery stenosis is a significant predictor of perioperative stroke risk in patients undergoing coronary artery bypass grafting (CABG). Identifying noninvasive, simple, and clinically relevant biomarkers for risk stratification is crucial in this population. The CALLY index, a composite marker reflecting systemic inflammation and nutritional status, has shown prognostic value in various diseases. However, its relationship with carotid artery stenosis in patients undergoing isolated CABG remains unclear. This study aimed to evaluate the relationship between carotid artery stenosis and the CALLY index in patients undergoing isolated CABG.
Methods: This retrospective, single-center study included 820 patients who underwent isolated CABG and preoperative carotid Doppler ultrasonography between January 2020 and December 2024. The degree of carotid artery stenosis was classified into three groups (<50, 50-70, >70%). CALLY index values were calculated using lymphocyte count, albumin, and C-reactive protein (CRP) levels. Statistical analyses included Kruskal-Wallis H and Spearman's rank correlation tests.
Results: The CALLY index was significantly lower in patients with higher degrees of carotid artery stenosis (P < 0.001). A strong negative correlation was found between the CALLY index and carotid stenosis severity (Spearman's rho = -0.831, P < 0.001).
Conclusion: Low CALLY index values are significantly associated with the presence and severity of carotid artery stenosis in patients undergoing isolated CABG. The CALLY index may serve as a simple and practical biomarker for preoperative risk assessment, aiding in the identification of high-risk patients and potentially improving surgical outcomes.
期刊介绍：
Coronary Artery Disease welcomes reports of original research with a clinical emphasis, including observational studies, clinical trials, translational research, novel imaging, pharmacology and interventional approaches as well as advances in laboratory research that contribute to the understanding of coronary artery disease. Each issue of Coronary Artery Disease is divided into four areas of focus: Original Research articles, Review in Depth articles by leading experts in the field, Editorials and Images in Coronary Artery Disease. The Editorials will comment on selected original research published in each issue of Coronary Artery Disease, as well as highlight controversies in coronary artery disease understanding and management.
Submitted artcles undergo a preliminary review by the editor. Some articles may be returned to authors without further consideration. Those being considered for publication will undergo further assessment and peer-review by the editors and those invited to do so from a reviewer pool.
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