Yanbing Jiang, Li Xie, Lorenzo Azzalinilini, Xiaohui Zhao
{"title":"Optical coherence tomography assessment of retrograde wire in chronic total occlusion percutaneous coronary intervention.","authors":"Yanbing Jiang, Li Xie, Lorenzo Azzalinilini, Xiaohui Zhao","doi":"10.1097/MCA.0000000000001528","DOIUrl":"https://doi.org/10.1097/MCA.0000000000001528","url":null,"abstract":"","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143981515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ha Jeong Lim, Lee Bom, Seung-Yul Lee, Jae Youn Moon, Sang-Hoon Kim, Jung-Hoon Sung, In Jai Kim, Sang-Wook Lim, Dong-Hun Cha, Se Hun Kang
{"title":"Sex differences in the impact of marital status on coronary artery disease outcomes in Korea.","authors":"Ha Jeong Lim, Lee Bom, Seung-Yul Lee, Jae Youn Moon, Sang-Hoon Kim, Jung-Hoon Sung, In Jai Kim, Sang-Wook Lim, Dong-Hun Cha, Se Hun Kang","doi":"10.1097/MCA.0000000000001527","DOIUrl":"https://doi.org/10.1097/MCA.0000000000001527","url":null,"abstract":"<p><strong>Background: </strong>Coronary artery disease (CAD) outcomes are influenced by social determinants, including marital status. However, research on the sex-specific effects of marital status on CAD outcomes is limited. This study aimed to evaluate the relationship between marital status and clinical outcomes of patients with CAD stratified according to sex in Korea.</p><p><strong>Methods: </strong>A total of 3476 patients with CAD who underwent percutaneous coronary intervention (PCI) were enrolled in this retrospective observational study. Patients were categorized into married and nonmarried groups based on demographic data at the time of admission. The primary endpoint was all-cause mortality.</p><p><strong>Results: </strong>Among the study population, 20.7% of women and 11.5% of men who underwent PCI for CAD were nonmarried. For 87.1% of nonmarried women, the cause of being nonmarried was the death of a spouse, whereas for 48.3% of unmarried men, the most common cause was being unmarried. During a median follow-up of 53.3 months, in analysis using the Cox proportional hazard regression model, nonmarried status was associated with higher all-cause [adjusted hazard ratio (HR): 2.24, 95% confidence interval (CI): 1.22-4.09, P = 0.009] and cardiovascular (adjusted HR: 2.63, 95% CI: 19.91-5.80, P = 0.017) deaths in men but not in women.</p><p><strong>Conclusion: </strong>Marital status independently predicted the adverse outcomes in men with CAD but not in women, highlighting the importance of sex-specific approaches to the assessment of social determinants in cardiovascular care. Future studies should explore broader social and economic factors to inform targeted interventions.</p>","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143991723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ilke Erbay, Pelin Aladag, Naile Eris Gudul, Ugur Kokturk, Melisa Begum Kisa, Ahmet Avci
{"title":"Enhancing the diagnostic specificity of exercise ECG testing in obstructive coronary artery disease: the role of the Selvester QRS score.","authors":"Ilke Erbay, Pelin Aladag, Naile Eris Gudul, Ugur Kokturk, Melisa Begum Kisa, Ahmet Avci","doi":"10.1097/MCA.0000000000001525","DOIUrl":"https://doi.org/10.1097/MCA.0000000000001525","url":null,"abstract":"<p><strong>Background: </strong>Exercise ECG testing is a widely used, noninvasive tool for detecting obstructive coronary artery disease (OCAD). However, its diagnostic performance is often limited by low specificity, leading to false-positive results and unnecessary invasive procedures.</p><p><strong>Objective: </strong>This study aims to assess the potential of combining the Selvester QRS score with exercise ECG to enhance diagnostic specificity for OCAD in patients with suspected stable angina.</p><p><strong>Methods: </strong>This retrospective study included 203 patients who presented with chest pain, underwent exercise ECG and were assessed for OCAD by coronary angiography or computed tomography angiography. Receiver operating characteristic analysis identified the optimal Selvester QRS score cutoff and assessed the diagnostic performance of exercise ECG and the combined model. Multivariable logistic regression was performed in the exercise ECG positive and negative groups.</p><p><strong>Results: </strong>Of the 203 patients, 116 were diagnosed with OCAD. The optimal Selvester QRS score cutoff was ≥3, with a sensitivity of 83.6% and a specificity of 93.1%. The combination of a positive exercise ECG and a Selvester QRS score ≥3 achieved the highest specificity (98.9%). Regression analyses showed that Selvester QRS score ≥3 was an independent predictor of OCAD, even in patients with negative exercise ECG results (adjusted odds ratio: 7.018; P < 0.001).</p><p><strong>Conclusion: </strong>The Selvester QRS score can improve the specificity of the exercise ECG in detecting OCAD in patients with suspected stable angina. This approach has the potential to reduce false positives and unnecessary invasive procedures by improving risk stratification.</p>","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143771704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Spontaneous formation of an arteriovenous fistula: an unusual decompression pathway for septal collateral perforation and hematoma.","authors":"Minggang Zhou, Li Chen","doi":"10.1097/MCA.0000000000001526","DOIUrl":"https://doi.org/10.1097/MCA.0000000000001526","url":null,"abstract":"","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143751508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Charalampos Varlamos, Iosif Xenogiannis, Maria A Mademli, Vasilios D Kollias, Loukianos S Rallidis
{"title":"Left main coronary artery atresia: an extremely rare albeit lethal congenital coronary anomaly.","authors":"Charalampos Varlamos, Iosif Xenogiannis, Maria A Mademli, Vasilios D Kollias, Loukianos S Rallidis","doi":"10.1097/MCA.0000000000001518","DOIUrl":"https://doi.org/10.1097/MCA.0000000000001518","url":null,"abstract":"","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143691402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Anomalous left coronary artery arising from the right sinus of Valsalva with an intramural course.","authors":"Leizhi Ku, Zheng Liu, Xiaojing Ma","doi":"10.1097/MCA.0000000000001519","DOIUrl":"https://doi.org/10.1097/MCA.0000000000001519","url":null,"abstract":"","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tereza Luiza B Fakhouri, Daphnne Camaroske Vera, Viviane Aparecida R Sant'Anna, Esteferson F Rodrigues, Nelson C Farias, Maria Cristina O Izar, Francisco Antonio Fonseca, Magnus Gidlund, Henrique A R Fonseca
{"title":"Circulation of natural autoantibodies against an immunodominant region of the apolipoprotein B after an acute coronary syndrome: a prospective observational study.","authors":"Tereza Luiza B Fakhouri, Daphnne Camaroske Vera, Viviane Aparecida R Sant'Anna, Esteferson F Rodrigues, Nelson C Farias, Maria Cristina O Izar, Francisco Antonio Fonseca, Magnus Gidlund, Henrique A R Fonseca","doi":"10.1097/MCA.0000000000001517","DOIUrl":"https://doi.org/10.1097/MCA.0000000000001517","url":null,"abstract":"","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143540466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Coronary artery diseasePub Date : 2025-03-01Epub Date: 2024-11-27DOI: 10.1097/MCA.0000000000001459
Fernando Alfonso, Tamaz Shaburishvili, Bruno Farah, Ikrali Gogorishvili, Jacques Monsegu, Arvydas Baranauskas, Erwan Bressollette, George Shaburishvili, Javier Cuesta, Fernando Rivero, Raul Moreno, Manel Sabate
{"title":"First-in-man study of a novel everolimus-coated balloon for the treatment of coronary in-stent restenosis.","authors":"Fernando Alfonso, Tamaz Shaburishvili, Bruno Farah, Ikrali Gogorishvili, Jacques Monsegu, Arvydas Baranauskas, Erwan Bressollette, George Shaburishvili, Javier Cuesta, Fernando Rivero, Raul Moreno, Manel Sabate","doi":"10.1097/MCA.0000000000001459","DOIUrl":"10.1097/MCA.0000000000001459","url":null,"abstract":"<p><strong>Background: </strong>Treatment of patients with in-stent restenosis (ISR) remains challenging. In this setting the use of drug-coated balloons (DCB) represents an attractive approach to avoid adding another metal layer to the coronary wall.</p><p><strong>Aims: </strong>The Chansu Vascular Technologies (CVT)-ISR trial aimed to evaluate the safety and efficacy of a novel everolimus-DCB (CVT-DCB) using a new coating formulation and crystalline everolimus.</p><p><strong>Methods: </strong>The CVT-ISR trial was a prospective, multicenter, open, single-arm, first-in-man (FIM) study. A total of 51 patients (mean age 69.2 years, 74.5% male) with single ISR coronary lesions (≤24 mm in length) were enrolled at nine sites in Europe.</p><p><strong>Results: </strong>The primary safety endpoint, freedom from target lesion failure (TLF) at 180 days, was 92.2%, with the lower bound of the 95% confidence interval (81.1%), above the protocol-defined objective performance criterion (OPC) (65% for conventional balloon angioplasty, P < 0.05). At 1 year freedom from TLF was 90.2%. The primary efficacy endpoint, in-stent late lumen loss at 180 days (evaluated in a predefined subgroup of 25 patients scheduled for late angiography), was 0.40 mm (median 0.30 mm), lower than the protocol-defined OPC of the plain balloon angioplasty historical control (0.80 mm, P < 0.001).</p><p><strong>Conclusion: </strong>This FIM study demonstrated the superior efficacy of the new everolimus CVT-DCB compared with conventional balloon angioplasty in the treatment of patients with ISR.</p><p><strong>Clinical trials registration: </strong>NCT05731700.</p>","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":"91-98"},"PeriodicalIF":1.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142726701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}