Ahmet Yaşar Çizgici, Aybüke Şimşek, Hande Uysal, Ahmet Güner, Mehmet Baran Karataş, Elnur Alizade, Ali Nazmi Çalik, İrfan Şahin, İbrahim Faruk Aktürk, Serkan Kahraman, Ömer Taşbulak, Ezgi Gültekin Güner, Ebru Serin, Veysel Ozan Tanik, Abdullah Doğan, Kaan Gökçe, Enes Arslan, Hamdi Püşüroğlu, Muhammed Furkan Deniz, Cemalettin Akman, Murat Gökalp, İlyas Çetin, Berkay Serter, Koray Çiloğlu, Mehmet Kocaağa, Kudret Keskin, Saner Bahadir Gök, Fatih Furkan Bedir, Eyüp Karaer, Ahmet Arif Yalçin, Fatih Uzun
{"title":"双吻合器或小挤压支架置入术治疗真冠状动脉分叉病变：多中心COLLECT-BIF登记。","authors":"Ahmet Yaşar Çizgici, Aybüke Şimşek, Hande Uysal, Ahmet Güner, Mehmet Baran Karataş, Elnur Alizade, Ali Nazmi Çalik, İrfan Şahin, İbrahim Faruk Aktürk, Serkan Kahraman, Ömer Taşbulak, Ezgi Gültekin Güner, Ebru Serin, Veysel Ozan Tanik, Abdullah Doğan, Kaan Gökçe, Enes Arslan, Hamdi Püşüroğlu, Muhammed Furkan Deniz, Cemalettin Akman, Murat Gökalp, İlyas Çetin, Berkay Serter, Koray Çiloğlu, Mehmet Kocaağa, Kudret Keskin, Saner Bahadir Gök, Fatih Furkan Bedir, Eyüp Karaer, Ahmet Arif Yalçin, Fatih Uzun","doi":"10.1097/MCA.0000000000001560","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>This multicenter observational study aimed to retrospectively evaluate the mid-term clinical outcomes of the mini-crush technique (MCT) and double kissing culotte technique (DKCT) in patients with coronary bifurcation lesions (CBLs).</p><p><strong>Methods: </strong>This large-scale, multicenter study (n = 8) included patients with CBLs who underwent percutaneous coronary intervention with either MCT or DKCT. The primary endpoint was defined as major adverse cardiac events (MACE), which include cardiac death, target vessel myocardial infarction, or clinically driven target lesion revascularization.</p><p><strong>Results: </strong>A total of 728 patients [male: 584 (80.2%), mean age: 60.93 ± 10.46 years] were included. The initial revascularization strategy was MCT in 476 (65.4%) cases and DKCT in 252 (34.6%) cases. The number of balloons used (6.30 ± 1.84 vs. 5.43 ± 1.99, P < 0.001) and procedure time (65.10 ± 20.34 vs. 61.30 ± 18.48 min, P = 0.020) were significantly higher in the DKCT group. In multivariate Cox regression analysis, risk-adjusted mid-term MACE [hazard ratio (HR): 0.645, (95% confidence interval: 0.395-1.053), P = 0.079] did not differ in the MCT group compared to the DKCT group. Additionally, chronic kidney disease (HR = 2.434, P < 0.001), high SYNTAX score (HR = 1.085, P < 0.001), final kissing balloon inflation (HR = 0.110, P < 0.001), presence of nonfatal intraprocedural complications (HR = 5.818, P < 0.001), and high total cholesterol level (HR = 1.007, P = 0.005) were found to be independent predictors of MACE.</p><p><strong>Conclusion: </strong>This multicenter registry demonstrates that in patients with CBLs, the risk-adjusted MACE rate was similar between both techniques, with a nonsignificant trend favoring MCT at mid-term follow-up.</p>","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":""},"PeriodicalIF":2.0000,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Double kissing culotte or mini-crush stenting for true coronary bifurcation lesions: the multicenter COLLECT-BIF registry.\",\"authors\":\"Ahmet Yaşar Çizgici, Aybüke Şimşek, Hande Uysal, Ahmet Güner, Mehmet Baran Karataş, Elnur Alizade, Ali Nazmi Çalik, İrfan Şahin, İbrahim Faruk Aktürk, Serkan Kahraman, Ömer Taşbulak, Ezgi Gültekin Güner, Ebru Serin, Veysel Ozan Tanik, Abdullah Doğan, Kaan Gökçe, Enes Arslan, Hamdi Püşüroğlu, Muhammed Furkan Deniz, Cemalettin Akman, Murat Gökalp, İlyas Çetin, Berkay Serter, Koray Çiloğlu, Mehmet Kocaağa, Kudret Keskin, Saner Bahadir Gök, Fatih Furkan Bedir, Eyüp Karaer, Ahmet Arif Yalçin, Fatih Uzun\",\"doi\":\"10.1097/MCA.0000000000001560\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>This multicenter observational study aimed to retrospectively evaluate the mid-term clinical outcomes of the mini-crush technique (MCT) and double kissing culotte technique (DKCT) in patients with coronary bifurcation lesions (CBLs).</p><p><strong>Methods: </strong>This large-scale, multicenter study (n = 8) included patients with CBLs who underwent percutaneous coronary intervention with either MCT or DKCT. The primary endpoint was defined as major adverse cardiac events (MACE), which include cardiac death, target vessel myocardial infarction, or clinically driven target lesion revascularization.</p><p><strong>Results: </strong>A total of 728 patients [male: 584 (80.2%), mean age: 60.93 ± 10.46 years] were included. The initial revascularization strategy was MCT in 476 (65.4%) cases and DKCT in 252 (34.6%) cases. The number of balloons used (6.30 ± 1.84 vs. 5.43 ± 1.99, P < 0.001) and procedure time (65.10 ± 20.34 vs. 61.30 ± 18.48 min, P = 0.020) were significantly higher in the DKCT group. In multivariate Cox regression analysis, risk-adjusted mid-term MACE [hazard ratio (HR): 0.645, (95% confidence interval: 0.395-1.053), P = 0.079] did not differ in the MCT group compared to the DKCT group. 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Double kissing culotte or mini-crush stenting for true coronary bifurcation lesions: the multicenter COLLECT-BIF registry.
Background: This multicenter observational study aimed to retrospectively evaluate the mid-term clinical outcomes of the mini-crush technique (MCT) and double kissing culotte technique (DKCT) in patients with coronary bifurcation lesions (CBLs).
Methods: This large-scale, multicenter study (n = 8) included patients with CBLs who underwent percutaneous coronary intervention with either MCT or DKCT. The primary endpoint was defined as major adverse cardiac events (MACE), which include cardiac death, target vessel myocardial infarction, or clinically driven target lesion revascularization.
Results: A total of 728 patients [male: 584 (80.2%), mean age: 60.93 ± 10.46 years] were included. The initial revascularization strategy was MCT in 476 (65.4%) cases and DKCT in 252 (34.6%) cases. The number of balloons used (6.30 ± 1.84 vs. 5.43 ± 1.99, P < 0.001) and procedure time (65.10 ± 20.34 vs. 61.30 ± 18.48 min, P = 0.020) were significantly higher in the DKCT group. In multivariate Cox regression analysis, risk-adjusted mid-term MACE [hazard ratio (HR): 0.645, (95% confidence interval: 0.395-1.053), P = 0.079] did not differ in the MCT group compared to the DKCT group. Additionally, chronic kidney disease (HR = 2.434, P < 0.001), high SYNTAX score (HR = 1.085, P < 0.001), final kissing balloon inflation (HR = 0.110, P < 0.001), presence of nonfatal intraprocedural complications (HR = 5.818, P < 0.001), and high total cholesterol level (HR = 1.007, P = 0.005) were found to be independent predictors of MACE.
Conclusion: This multicenter registry demonstrates that in patients with CBLs, the risk-adjusted MACE rate was similar between both techniques, with a nonsignificant trend favoring MCT at mid-term follow-up.
期刊介绍：
Coronary Artery Disease welcomes reports of original research with a clinical emphasis, including observational studies, clinical trials, translational research, novel imaging, pharmacology and interventional approaches as well as advances in laboratory research that contribute to the understanding of coronary artery disease. Each issue of Coronary Artery Disease is divided into four areas of focus: Original Research articles, Review in Depth articles by leading experts in the field, Editorials and Images in Coronary Artery Disease. The Editorials will comment on selected original research published in each issue of Coronary Artery Disease, as well as highlight controversies in coronary artery disease understanding and management.
Submitted artcles undergo a preliminary review by the editor. Some articles may be returned to authors without further consideration. Those being considered for publication will undergo further assessment and peer-review by the editors and those invited to do so from a reviewer pool.
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