Coronary artery disease最新文献_第6页

Efficacy and safety of coronary sinus reducer for refractory angina: a systematic review and meta-analysis of randomized controlled trials. 冠状窦减压器治疗难治性心绞痛的有效性和安全性：随机对照试验的系统回顾和荟萃分析。

IF 1.5 4区医学

Coronary artery disease Pub Date : 2025-06-01 Epub Date: 2024-10-31 DOI: 10.1097/MCA.0000000000001451

Ahmed Mazen Amin, Ubaid Khan, Yehya Khlidj, Basant E Katamesh, Hossam Elbenawi, Abdelrahman Ewis, Amer Hammad

{"title":"Efficacy and safety of coronary sinus reducer for refractory angina: a systematic review and meta-analysis of randomized controlled trials.","authors":"Ahmed Mazen Amin, Ubaid Khan, Yehya Khlidj, Basant E Katamesh, Hossam Elbenawi, Abdelrahman Ewis, Amer Hammad","doi":"10.1097/MCA.0000000000001451","DOIUrl":"10.1097/MCA.0000000000001451","url":null,"abstract":"Refractory angina affects patients' quality of life around the world. Coronary sinus reducer (CSR) is a new therapeutic approach that has been investigated in recent years. We aimed to investigate the efficacy and safety of CSR for refractory angina. We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) from PubMed, Web of Science, Scopus, Embase, and CENTRAL searches until May 2024. Dichotomous data were pooled using risk ratio (RR), and continuous data were pooled using mean difference (MD), both with a 95% confidence interval (CI), using (R version 4.3). With the inclusion of three RCTs, our cohort comprised a total of 180 patients. Compared with the control group, after 6 months, CSR was significantly associated with a decreased mean change of Canadian Cardiovascular Society (CCS) class [MD: -0.54 with 95% CI (-0.80 to -0.27), P < 0.01], a decreased number of patients in the CCS class III/IV [RR: 0.56 with 95% CI (0.38-0.84), P < 0.01], and increased exercise time [MD: 50.46 with 95% CI (9.47-91.45), P = 0.02]. However, there was no significant difference between CSR and the control group in double products, all Seattle Angina Questionnaire domains, and safety outcomes. CSR has been shown to reduce angina severity by lowering CCS class scores and increasing exercise time. Large-scale RCTs are needed to confirm its effectiveness in patients with refractory angina.","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":"337-347"},"PeriodicalIF":1.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142544225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Calcified aneurysm in the left anterior descending artery. 左前降支动脉钙化动脉瘤。

IF 1.5 4区医学

Coronary artery disease Pub Date : 2025-06-01 Epub Date: 2024-10-15 DOI: 10.1097/MCA.0000000000001436

Rachelle Bishay, Srikanth Krishnan, Matthew J Budoff

引用次数: 0

Coronary vasomotor response incidence to intracoronary acetylcholine provocation test according to the severity of insignificant coronary artery stenosis in Korean population. 韩国人冠状动脉狭窄不明显时冠状动脉内乙酰胆碱激发试验的冠状动脉血管运动反应发生率。

IF 1.5 4区医学

Coronary artery disease Pub Date : 2025-06-01 Epub Date: 2025-04-29 DOI: 10.1097/MCA.0000000000001481

Tae Shik Park, Woo Jin Ahn, Seung-Woon Rha, Se Yeon Choi, Jinah Cha, Sujin Hyun, Markz Rmp Sinurat, Soohyung Park, Cheol Ung Choi, Chang Gyu Park, Dong Joo Oh, Byoung Geol Choi

{"title":"Coronary vasomotor response incidence to intracoronary acetylcholine provocation test according to the severity of insignificant coronary artery stenosis in Korean population.","authors":"Tae Shik Park, Woo Jin Ahn, Seung-Woon Rha, Se Yeon Choi, Jinah Cha, Sujin Hyun, Markz Rmp Sinurat, Soohyung Park, Cheol Ung Choi, Chang Gyu Park, Dong Joo Oh, Byoung Geol Choi","doi":"10.1097/MCA.0000000000001481","DOIUrl":"10.1097/MCA.0000000000001481","url":null,"abstract":"Background: Coronary artery spasm (CAS) is a cause of variant angina. However, the understanding of CAS patterns in the presence of mild-to-moderate coronary artery stenosis is limited. This study aimed to evaluate the incidence and patterns of CAS in patients with insignificant coronary artery stenosis using intracoronary acetylcholine (ACH) provocation test.Methods: In this study, 6513 patients without significant coronary artery stenosis who underwent intracoronary ACH provocation test were enrolled. Patients were divided into three groups, based on the severity of coronary artery stenosis: the non group (stenosis <30%, n = 2833), the mild group (30-49%, n = 3278) and the moderate group (50-69%, n = 402). Vasomotor responses were observed among three different groups.Results: The baseline characteristics of the patients in the mild and moderate groups were worse than in the non group. They were older, had higher prevalence of hypertension, diabetes, dyslipidemia, and smoking habit. During the ACH test, CAS was observed in 58.1% of the overall population. The mild group (60.1%) and the moderate group (60.9%) showed a higher incidence than the non group (55.3%, P < 0.001). In addition, among cases of CAS, the mild group (3.2%) and the moderate group (8.5%) responded more at a lowest dose of ACH than the non group (3.1%, P < 0.001).Conclusion: In patients with chest pain without significant coronary artery stenosis, CAS was observed in over half of the cases. Furthermore, CAS was found to be more frequent and more susceptible in patients with mild-to-moderate coronary artery stenosis compared with those without fixed stenosis.","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":"287-293"},"PeriodicalIF":1.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142834438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recurrent coronary in-stent restenosis and rapidly progressive coronary artery disease as initial manifestation of immunoglobulin G4-related disease. 复发性冠状动脉支架内再狭窄和快速进展的冠状动脉疾病是免疫球蛋白g4相关疾病的初始表现。

IF 1.5 4区医学

Coronary artery disease Pub Date : 2025-05-27 DOI: 10.1097/MCA.0000000000001537

Georgiana Pintea Bentea, Ahmad Awada, Vanessa Mary Crapanzano Minichello, Brahim Berdaoui

引用次数: 0

Late stent strut apposition and coverage after drug-eluting stent implantation by optical coherence tomography in patients with acute myocardial infarction. 光学相干断层扫描在急性心肌梗死患者药物洗脱支架植入术后支架支架的晚期支撑位置和覆盖。

IF 1.5 4区医学

Coronary artery disease Pub Date : 2025-05-27 DOI: 10.1097/MCA.0000000000001536

Cheol Hyun Lee, Seonhwa Lee, Jongmin Hwang, In-Cheol Kim, Yun-Kyeong Cho, Hyuck-Jun Yoon, Hyungseop Kim, Chang-Wook Nam, Seung-Ho Hur

{"title":"Late stent strut apposition and coverage after drug-eluting stent implantation by optical coherence tomography in patients with acute myocardial infarction.","authors":"Cheol Hyun Lee, Seonhwa Lee, Jongmin Hwang, In-Cheol Kim, Yun-Kyeong Cho, Hyuck-Jun Yoon, Hyungseop Kim, Chang-Wook Nam, Seung-Ho Hur","doi":"10.1097/MCA.0000000000001536","DOIUrl":"https://doi.org/10.1097/MCA.0000000000001536","url":null,"abstract":"Background: Although drug-eluting stents (DES) are effective, stent thrombosis (ST) remains a major concern in patients with acute myocardial infarction (AMI) who undergo DES implantation. We aimed to evaluate the incidence of late stent malapposition (SM) and uncovered struts 12 months after implantation of a bioabsorbable polymer everolimus-eluting stent (BP-EES) or a durable polymer zotarolimus-eluting stent (DP-ZES) in patients with AMI using optical coherence tomography (OCT).Methods: Sixty-nine patients with AMI were randomly assigned 2:1 to the BP-EES (46 patients) or DP-ZES (23 patients) groups. The coprimary endpoints were the incidences of late SM and uncovered stent struts in OCT strut-level analysis at 12 months postimplantation.Results: The 51 patients who completed the 12-month follow-up OCT (BP-EES, 36 patients, 39 lesions; DP-ZES, 15 patients, 18 lesions) showed no intergroup differences in the incidence of acute SM (BP-EES vs. DP-ZES; 12.25 ± 14.27% vs. 12.35 ± 10.55%, P = 0.981) at the index procedure. The incidence of late SM (0.12 ± 0.42% vs. 0.14 ± 0.25%, P = 0.873) and uncovered struts (1.69 ± 3.44% vs. 2.45 ± 3.23%, P = 0.532) also did not differ between the two DES groups at 12-month postimplantation.Conclusion: Twelve-month OCT measurements showed no significant differences in late SM and uncovered struts between the BP-EES and DP-ZES stents. Thus, contemporary second-generation DES show a very low rate of late SM and uncovered struts after 12 months in AMI, regardless of stent polymer type.Trial registration: Late stent strut apposition and coverage after drug-eluting stent implantation by OCT in patients with AMI (APPOSITION AMI-II) (NCT02770651).","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144149745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy of paclitaxel-coated versus uncoated balloon angioplasty for revascularization of coronary in-stent restenosis: a meta-analysis and metaregression. 紫杉醇包被与非包被球囊血管成形术对冠状动脉支架内再狭窄血运重建的疗效：一项荟萃分析和荟萃回归。

IF 1.5 4区医学

Coronary artery disease Pub Date : 2025-05-13 DOI: 10.1097/MCA.0000000000001534

Mrinal Murali Krishna, Meghna Joseph, Chidubem Ezenna, Vinicius Pereira, Ancy Jenil Franco, Mahmoud Ismayl, Jennifer Rymer, Andrew M Goldsweig

{"title":"Efficacy of paclitaxel-coated versus uncoated balloon angioplasty for revascularization of coronary in-stent restenosis: a meta-analysis and metaregression.","authors":"Mrinal Murali Krishna, Meghna Joseph, Chidubem Ezenna, Vinicius Pereira, Ancy Jenil Franco, Mahmoud Ismayl, Jennifer Rymer, Andrew M Goldsweig","doi":"10.1097/MCA.0000000000001534","DOIUrl":"https://doi.org/10.1097/MCA.0000000000001534","url":null,"abstract":"Background: Treatment of in-stent restenosis (ISR) accounts for 10% of percutaneous coronary interventions in the USA. Paclitaxel-coated balloons (PCBs) are an alternative to uncoated balloons (UCBs) for ISR.Methods: We systematically searched PubMed, Scopus, and Cochrane Central for studies comparing PCB with UCB in treating ISR. Outcomes included late lumen loss, binary restenosis, target lesion revascularization (TLR), and major adverse cardiovascular events (MACE).Results: Eight trials including 1410 patients [PCB in 865 (61%), follow-up 6 months to 10 years) were identified. Angiographic outcomes of late lumen loss [mean difference: -0.50 mm; 95% confidence interval (CI): -0.66 to -0.33; P < 0.01] and binary restenosis [relative risk (RR): 0.22; 95% CI: 0.13-0.40; P < 0.01] at 6-8 months were lower with PCB. TLR at 6 months (RR: 0.16; 95% CI: 0.06-0.40; P < 0.001) and 1 year (RR: 0.45; 95% CI: 0.31-0.66; P < 0.001), MACE at 6 months (RR: 0.25; 95% CI: 0.16-0.38; P < 0.001), MACE at 3-5 years (RR: 0.54; 95% CI: 0.37-0.80; P = 0.002), and TLR at 3-5 years (RR: 0.51; 95% CI: 0.29-0.90; P = 0.021) were lower with PCB. Meta-regression revealed that ISR lesions in the left anterior descending artery were associated with lower rates of binary restenosis while the opposite was observed for left circumflex lesions.Conclusion: Revascularization of coronary ISR with PCB is associated with reduced late lumen loss, binary restenosis, TLR, CCE, and MACE. PCB may be a preferred strategy for coronary ISR.","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143982256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Optical frequency domain imaging versus intravascular ultrasound for percutaneous coronary intervention: a meta-analysis and trial sequential analysis of randomized controlled trials. 经皮冠状动脉介入治疗的光学频域成像与血管内超声：随机对照试验的荟萃分析和试验序列分析。

IF 1.5 4区医学

Coronary artery disease Pub Date : 2025-05-12 DOI: 10.1097/MCA.0000000000001535

Hosam I Taha, Mohamed S Elgendy, Abdalhakim Shubietah, Ahmed Mazen Amin, Mohamed R Ezz, Abdelrahman M Ghazal, Mohamed Anas ElShanat, Hazem Zayan, Khalid Tolba, Mohamed Abuelazm, Islam Y Elgendy

{"title":"Optical frequency domain imaging versus intravascular ultrasound for percutaneous coronary intervention: a meta-analysis and trial sequential analysis of randomized controlled trials.","authors":"Hosam I Taha, Mohamed S Elgendy, Abdalhakim Shubietah, Ahmed Mazen Amin, Mohamed R Ezz, Abdelrahman M Ghazal, Mohamed Anas ElShanat, Hazem Zayan, Khalid Tolba, Mohamed Abuelazm, Islam Y Elgendy","doi":"10.1097/MCA.0000000000001535","DOIUrl":"https://doi.org/10.1097/MCA.0000000000001535","url":null,"abstract":"Intravascular ultrasound (IVUS) or optical frequency domain imaging (OFDI) for guiding percutaneous coronary interventions (PCI) reduces the risk of adverse events compared with angiographic guidance. However, only a few trials compared both modalities. This study aims to assess and compare OFDI- vs. IVUS-guided PCI. We conducted a meta-analysis of randomized controlled trials (RCTs) retrieved from PubMed, Scopus, WOS, Embase, and Cochrane Library till September 2024. The primary outcome was major adverse cardiac events (MACE). Risk ratios (RR) were applied for dichotomous outcomes and mean differences (MD) for continuous outcomes, both with 95% confidence intervals (CI). PROSPERO ID: CRD42024595477. Four RCTs with 1135 patients were included. There was no significant difference between the two modalities in terms of MACE [RR: 0.99; 95% CI: (0.53, 1.86); P = 0.98], all-cause mortality [RR: 0.72; 95% CI: (0.15, 3.56); P = 0.69], cardiac mortality [RR: 1.00; 95% CI: (0.18, 5.68); P = 1.00] and myocardial infarction [RR: 1.21; 95% CI: (0.35, 4.18); P = 0.76]. Additionally, there was no significant difference in PCI success [RR: 1.00; 95% CI: (0.99, 1.02); P = 0.64]. However, OFDI was associated with a significant increase in contrast volume [MD: 19.81 ml; 95% CI: (2.53, 37.09); P = 0.02] and reduction in fluoroscopy time [MD: -7.05 min; 95% CI: (-9.32, -4.79); P < 0.01]. This meta-analysis of RCTs suggests that OFDI is comparable to IVUS in efficacy and safety for guiding PCI, with no significant differences in clinical outcomes. These findings support the use of either modality for PCI guidance. However, additional large-scale, multicenter RCTs to recommended to validate these findings and enhance their generalizability.","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143957045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Urinary sodium-potassium ratio as a genetic predictor of myocardial infarction. 尿钠钾比作为心肌梗死的遗传预测因子。

IF 1.5 4区医学

Coronary artery disease Pub Date : 2025-05-06 DOI: 10.1097/MCA.0000000000001532

Ziyang Wu, Dong Wang, Chengchun Tang

{"title":"Urinary sodium-potassium ratio as a genetic predictor of myocardial infarction.","authors":"Ziyang Wu, Dong Wang, Chengchun Tang","doi":"10.1097/MCA.0000000000001532","DOIUrl":"https://doi.org/10.1097/MCA.0000000000001532","url":null,"abstract":"Background: The relationship between the urinary sodium-potassium ratio (USPR) and risk factors for heart disease has been observed over time. We evaluated the relationship between USPR and myocardial infarction (MI).Methods: Causal relationships were estimated based on USPR and MI data from genome-wide association studies. The main analysis method for bidirectional two-sample Mendelian randomization was inverse-variance weighting (IVW), with four other supplementary methods used.Results: The IVW method indicated a positive correlation between USPR levels and MI (IVW, odds ratio = 1.504, 95% confidence interval: 1.108-2.041, P = 0.009). In contrast, the inverse analysis provided evidence suggesting that MI affected USPR (P > 0.05). The Cochran Q test showed heterogeneity, while the intercept test revealed no horizontal pleiotropy, and the leave-one-out analysis demonstrated that the analyses were reliable.Conclusions: This study provides evidence for the causal effect of the USPR on MI; however, this was not the case in the opposite situation. It is plausible that the USPR serves as a promoting factor for MI.","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143955438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Predicting postoperative atrial fibrillation after cardiac surgery using the Naples prognostic score. 应用那不勒斯预后评分预测心脏手术后房颤。

IF 1.5 4区医学

Coronary artery disease Pub Date : 2025-05-01 Epub Date: 2024-10-24 DOI: 10.1097/MCA.0000000000001438

Dogac Oksen, Baris Guven, Ayca Donmez, Mehmet Ali Yesiltas, Ahmet Ozan Koyuncu, Seran Gulbudak, Veysel Oktay

{"title":"Predicting postoperative atrial fibrillation after cardiac surgery using the Naples prognostic score.","authors":"Dogac Oksen, Baris Guven, Ayca Donmez, Mehmet Ali Yesiltas, Ahmet Ozan Koyuncu, Seran Gulbudak, Veysel Oktay","doi":"10.1097/MCA.0000000000001438","DOIUrl":"10.1097/MCA.0000000000001438","url":null,"abstract":"Introduction: The Naples prognostic score (NPS) is a novel indicator of nutritional and inflammatory statuses in cancer patients. Development of atrial fibrillation after cardiac surgery (POAF) is a common complication that increases the incidence of adverse events. Numerous studies have investigated predictors of POAF. Yet, this study is the first to evaluate the prognostic value of NPS in predicting the development of POAF.Materials and methods: The population of this retrospective single-center case-control study consisted of all consecutive patients who underwent cardiac surgery between January 2021 and December 2023. The patients included in the study sample were divided into two groups according to whether they had POAF (group POAF) or remained in sinus rhythm (group RSR). Univariate and multivariate analyses were conducted to identify the variables that significantly predicted the development of POAF.Results: This study consisted of 860 patients with a mean age of 61.77 ± 9.13 years and 77.5% ( n = 667) were male. The incidence of POAF in the sample was 24.8% ( n = 214). NPS was significantly higher in group POAF than in group RSR (2.18 ± 0.99 vs. 1.96 ± 1.02, P = 0.008). Multivariate analysis revealed age [odds ratio (OR): 1.242, 95% confidence interval (CI): 1.020-1.304, P < 0.001] and high NPS (OR: 1.698, 95% CI: 1.121-1.930, P < 0.010) as independent predictors of POAF.Conclusion: High NPS values, along with advanced age, were found to be strongly associated with an increased risk of developing POAF. Therefore, it is concluded that NPS is a significant and independent predictor of POAF in patients undergoing cardiac surgery.","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":"225-231"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11949236/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142946189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Risk of new postoperative atrial fibrillation after cardiac surgery. 心脏手术后新发房颤的风险。

IF 1.5 4区医学

Coronary artery disease Pub Date : 2025-05-01 Epub Date: 2025-03-26 DOI: 10.1097/MCA.0000000000001472

Mesut Engin, İsmail Sivri

引用次数: 0