Coronary artery disease最新文献_第5页

Caveats in application of protected rotational atherectomy with double-guiding catheter technique for nonleft main bifurcation lesion. 双导导管保护旋转动脉粥样硬化切除术在非左主干分叉病变中的应用注意事项。

IF 2 4区医学

Coronary artery disease Pub Date : 2025-09-01 Epub Date: 2025-07-30 DOI: 10.1097/MCA.0000000000001476

Minggang Zhou, Li Chen

引用次数: 0

Short-term effects of upstream high bolus dose of tirofiban in patients with ST segment elevation myocardial infarction undergoing primary percutaneous coronary intervention. 上游大剂量替罗非班对ST段抬高型心肌梗死患者经皮冠状动脉介入治疗的短期疗效。

IF 2 4区医学

Coronary artery disease Pub Date : 2025-09-01 Epub Date: 2025-07-30 DOI: 10.1097/MCA.0000000000001501

Amr E I Abouelnour, Eman Q Mohammed, Doaa A Fouad, Aly Tohamy

{"title":"Short-term effects of upstream high bolus dose of tirofiban in patients with ST segment elevation myocardial infarction undergoing primary percutaneous coronary intervention.","authors":"Amr E I Abouelnour, Eman Q Mohammed, Doaa A Fouad, Aly Tohamy","doi":"10.1097/MCA.0000000000001501","DOIUrl":"10.1097/MCA.0000000000001501","url":null,"abstract":"Background: No-reflow following primary percutaneous coronary intervention (PPCI) is challenging to treat.Objectives: The objective of this study is to evaluate the efficacy and safety of upstream high-bolus-dose tirofiban administration in ST-segment elevation myocardial infarction (STEMI) cases undergoing PPCI on top of dual antiplatelet therapy, including ticagrelor, in comparison to selective bailout administration.Methods: This hospital-based, randomized, single-blinded prospective interventional study was conducted on 150 patients at Assiut University Heart Hospital. Patients with STEMI within 12 h after symptom onset who underwent PPCI were randomized to an upstream group ( n = 75) and a selective bailout group ( n = 75) based on the timing of the tirofiban bolus administration (25 µg/kg intravenously over 5 min).Results: The bailout group's thrombolysis in myocardial infarction (TIMI) frame count was higher than the upstream group's, despite comparable TIMI flow and myocardial blush grade between the two groups, but only approached statistical significance [14.4 (4-36) vs 12.2 (5-55), P = 0.08]. The enzymatic infarct size tended to be lower in the upstream group. All echocardiographic findings were comparable between the two studied groups, with no significant difference ( P > 0.05). There was no significant difference between the two groups regarding clinical outcomes.Conclusion: Compared to selective bailout administration, upstream high bolus dose of tirofiban in STEMI patients undergoing primary coronary intervention did not significantly affect angiographic outcomes, left ventricular remodeling, or function, despite smaller infarction size.","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":"488-495"},"PeriodicalIF":2.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143001325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical outcomes of rotational atherectomy followed by cutting balloon for calcified coronary lesions. 旋转动脉粥样硬化切除术后球囊切割治疗钙化冠状动脉病变的临床效果。

IF 2 4区医学

Coronary artery disease Pub Date : 2025-09-01 Epub Date: 2025-02-21 DOI: 10.1097/MCA.0000000000001515

Tingquan Zhou, Xian Jin, Shixin Ma, Jiming Han, Chengxing Shen

{"title":"Clinical outcomes of rotational atherectomy followed by cutting balloon for calcified coronary lesions.","authors":"Tingquan Zhou, Xian Jin, Shixin Ma, Jiming Han, Chengxing Shen","doi":"10.1097/MCA.0000000000001515","DOIUrl":"10.1097/MCA.0000000000001515","url":null,"abstract":"Objective: Rotational atherectomy is an effective method for treating severe coronary artery calcification; however, several challenges in its clinical application persist. This study aimed to compare the safety and effectiveness of rotational atherectomy combined with cutting balloon (RACB) versus rotational atherectomy with plain balloon (RAPB) in patients with heavily calcified coronary lesions.Methods: This retrospective observational cohort study included 326 patients who underwent rotational atherectomy at Shanghai Sixth People's Hospital from January 2016 to December 2022. Patients were divided into two groups (RACB and RAPB) on the basis of the type of balloon used. The primary outcome was the incidence of major adverse cardiovascular events (MACE) 1 year after percutaneous coronary intervention. Propensity score matching (PSM) was applied to minimize bias, and survival analyses were performed with the Cox proportional hazards model.Results: The procedural complication rates of the patients in the RACB and RAPB groups were comparable. Baseline covariates were balanced between groups after adjustment via PSM. Patients receiving RACB during their procedures had a lower MACE rate during the first postprocedural year in the unadjusted analysis (6.7% vs 16.2%, P < 0.05) and after adjustment with PSM (5.6% vs 16.1%, P < 0.01). The Kaplan-Meier survival curves revealed hazard ratios of 0.44 (95% CI: 0.23-0.82; P < 0.05) for the unadjusted model and 0.36 (95% CI: 0.17-0.76; P < 0.01) for the PSM-adjusted model.Conclusion: Performing RACB before stent implantation was demonstrated to be a safe and effective strategy for managing severely calcified coronary lesions.","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":"496-503"},"PeriodicalIF":2.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12316161/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of outcomes of Impella-assisted high-risk percutaneous coronary intervention in patients with and without prior coronary artery bypass graft. Impella辅助高风险经皮冠状动脉介入治疗在既往接受过冠状动脉旁路移植术和未接受过冠状动脉旁路移植术患者中的疗效比较。

IF 2 4区医学

Coronary artery disease Pub Date : 2025-09-01 Epub Date: 2024-12-19 DOI: 10.1097/MCA.0000000000001488

Mukunthan Murthi, Naveen Prasath, Anisha Memdani, Dhiran Sivasubramanian, Steve Attanasio, Gaurav Dhar, Neeraj Jolly, Aviral Vij

{"title":"Comparison of outcomes of Impella-assisted high-risk percutaneous coronary intervention in patients with and without prior coronary artery bypass graft.","authors":"Mukunthan Murthi, Naveen Prasath, Anisha Memdani, Dhiran Sivasubramanian, Steve Attanasio, Gaurav Dhar, Neeraj Jolly, Aviral Vij","doi":"10.1097/MCA.0000000000001488","DOIUrl":"10.1097/MCA.0000000000001488","url":null,"abstract":"Background: Limited data is available regarding in-hospital outcomes of patients undergoing high-risk percutaneous coronary intervention (HR-PCI) with Impella with and without a prior history of coronary artery bypass grafting (CABG).Methods: We performed a retrospective study from the Nationwide Inpatient Sample from year 2016 to 2020. We identified patients who underwent Impella and percutaneous coronary intervention on the same day and excluded those with cardiogenic shock. Subsequently, we stratified them into those with and without prior CABG.Results: During the study period, 18 925 patients underwent HR-PCI. Among these, 2043 (10.8%) patients had prior CABG. Patients without prior CABG had a higher percentage of acute coronary syndrome at presentation (62.7 vs 56.1%, P = 0.008). The proportion of females was significantly higher in those without prior CABG (32.4 vs 21.7%, P < 0.001). On multivariate analysis, there was no statistically significant difference in the in-hospital mortality (5.8% in CABG vs 8.5% in non-CABG, P = 0.52). Patients without prior CABG had higher rates of acute kidney injury, major bleeding, and blood transfusions. There were no significant differences in rates of cardiac arrest, ventricular arrhythmias, acute stroke, coronary dissections, and coronary perforations. Those without prior CABG had a longer duration of hospitalization (6.8 vs 9.3 days, P < 0.001) and higher hospital charges ($292 267 vs $322 206, P < 0.035).Conclusion: Our study highlights that a history of previous CABG does not increase the risk of in-hospital mortality in patients undergoing Impella-assisted HR-PCI but is associated with reduced rates of complications.","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":"467-473"},"PeriodicalIF":2.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142845865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Successful bail-out from severe balloon-induced coronary dissection by imaging-guide stent coverage for dissection entry point alone. 仅通过造影引导支架覆盖夹层入口，成功脱离球囊诱发的严重冠状动脉夹层。

IF 2 4区医学

Coronary artery disease Pub Date : 2025-09-01 Epub Date: 2024-10-31 DOI: 10.1097/MCA.0000000000001449

Koji Hayakawa, Kazuhiro Nakao, Kensuke Takagi, Teruo Noguchi

引用次数: 0

Impact of geriatric nutritional risk index on clinical outcomes in acute coronary syndrome patients: a comprehensive meta-analysis. 老年营养风险指数对急性冠状动脉综合征患者临床结局的影响：一项综合meta分析

IF 2 4区医学

Coronary artery disease Pub Date : 2025-09-01 Epub Date: 2025-01-20 DOI: 10.1097/MCA.0000000000001498

Denghong Zhang, Mingyang Tang, Nian Tang, Benjamin Samraj Prakash Earnest, Ihab Elsayed Mohamed Ali Abdou

{"title":"Impact of geriatric nutritional risk index on clinical outcomes in acute coronary syndrome patients: a comprehensive meta-analysis.","authors":"Denghong Zhang, Mingyang Tang, Nian Tang, Benjamin Samraj Prakash Earnest, Ihab Elsayed Mohamed Ali Abdou","doi":"10.1097/MCA.0000000000001498","DOIUrl":"10.1097/MCA.0000000000001498","url":null,"abstract":"Background: The Geriatric Nutritional Risk Index (GNRI), derived from serum albumin levels and body weight relative to ideal body weight, is a novel tool for assessing nutritional status. This meta-analysis explored the association between GNRI and the clinical outcomes in patients with acute coronary syndrome (ACS).Methods: We systematically searched PubMed , Embase , and Web of Science for studies evaluating the GNRI in patients with ACS. Inclusion criteria were observational studies reporting all-cause mortality or major adverse cardiovascular events (MACEs) among ACS patients categorized by low versus normal GNRI. Data extraction and quality assessment were independently performed by two authors, utilizing a random-effects model to account for potential heterogeneity.Results: Eleven cohort studies, encompassing 18 616 patients with ACS, were included. A low GNRI was associated with significantly increased risks of all-cause mortality (RR, 1.95; 95% CI, 1.63-2.34; P < 0.001; I ² = 32%) and MACEs (RR, 1.93; 95% CI, 1.62-2.29; P < 0.001; I ² = 25%). Subgroup analyses for the all-cause mortality outcome showed consistent findings across varied study designs, patient demographics, and follow-up periods ( P for subgroup differences all >0.05). Sensitivity analyses conducted by sequentially excluding individual studies confirmed the stability of these results.Conclusion: A low GNRI at the time of admission is a significant predictor of increased all-cause mortality and MACEs in patients with ACS.","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":"e33-e44"},"PeriodicalIF":2.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143001637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-term outcomes of second-generation drug-eluting stents versus coronary artery bypass graft: a systematic review and meta-analysis of randomized trials and multivariable adjusted data. 第二代药物洗脱支架与冠状动脉旁路移植术的长期结果：随机试验和多变量调整数据的系统回顾和荟萃分析

IF 2 4区医学

Coronary artery disease Pub Date : 2025-09-01 Epub Date: 2025-01-21 DOI: 10.1097/MCA.0000000000001503

André Luiz Carvalho Ferreira, Maria E Benitez, A E Lima, Almir Alamino Lacalle, Gabriel Saad, Camila Mota Guida

{"title":"Long-term outcomes of second-generation drug-eluting stents versus coronary artery bypass graft: a systematic review and meta-analysis of randomized trials and multivariable adjusted data.","authors":"André Luiz Carvalho Ferreira, Maria E Benitez, A E Lima, Almir Alamino Lacalle, Gabriel Saad, Camila Mota Guida","doi":"10.1097/MCA.0000000000001503","DOIUrl":"10.1097/MCA.0000000000001503","url":null,"abstract":"Long-term data are limited comparing percutaneous coronary intervention (PCI) with second-generation drug-eluting stents (S-DES) vs coronary artery bypass grafting (CABG) in patients with complex coronary artery disease (CAD). We aimed to conduct a systematic review and meta-analysis comparing these interventions in patients with left main or multivessel CAD. We systematically reviewed PubMed, Embase, and Cochrane for studies that compared PCI with S-DES and CABG in patients with left main or multivessel CAD with a minimum mean follow-up period of 3 years. Outcomes of interest were all-cause mortality, myocardial infarction (MI), stroke, and major adverse cardiovascular events (MACE). We extracted data from observational studies as multivariable-adjusted or propensity score-matched hazard ratio to minimize confounding and pooled hazard ratios with 95% confidence intervals (CIs) using a random effects model in Review Manager 5.4.1. We included 10 studies, 3 of which were randomized controlled trials, comprising a total of 26964 patients, of whom 14928 underwent PCI. As compared with CABG, S-DES had a significantly higher risk of all-cause mortality (hazard ratio 1.35; 95% CI 1.22-1.49; P < 0.001; I2 = 0%), MACE (hazard ratio 1.27; 95% CI 1.08-1.50; P = 0.005; I2 = 67%), and MI (hazard ratio 2.43; 95% CI 1.80-3.28; P < 0.01; I2 = 0%). There was no significant difference between groups in incidence of stroke. In this meta-analysis of patients with complex CAD, PCI with S-DES was associated with an increased risk of mortality, MI, and MACE compared with CABG.","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":"518-524"},"PeriodicalIF":2.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143001193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rescue primary percutaneous coronary intervention and left main bifurcation stenting via the arteria lusoria. 抢救性初级经皮冠状动脉介入治疗和经腔动脉的左主干分叉支架植入术。

IF 2 4区医学

Coronary artery disease Pub Date : 2025-09-01 Epub Date: 2024-10-24 DOI: 10.1097/MCA.0000000000001443

Konstantinos C Theodoropoulos, Evdoxia Stavropoulou, Matthaios Didagelos, Charalambos Kakderis, Alexandra Liakopoulou, Antonios Kouparanis, Vasileios Rafailidis, Antonios Ziakas

引用次数: 0

Heart's hidden link: intercoronary communication in a geriatric patient. 心脏的隐秘联系：老年患者的冠状动脉间沟通

IF 2 4区医学

Coronary artery disease Pub Date : 2025-09-01 Epub Date: 2024-11-06 DOI: 10.1097/MCA.0000000000001453

Ana Rita Teixeira, Bárbara Lacerda Teixeira, Pedro Garcia Brás, Tiago Mendonça, Rui Cruz Ferreira

引用次数: 0

Predicting severe multivessel coronary artery disease to guide access strategy in patients undergoing invasive coronary angiography. 预测严重多支血管冠状动脉疾病，为接受有创冠状动脉造影术的患者提供入路策略指导。

IF 2 4区医学

Coronary artery disease Pub Date : 2025-09-01 Epub Date: 2024-12-19 DOI: 10.1097/MCA.0000000000001490

Garry W Hamilton, David Chye, Hannah Johns, Jefferson Ko, Edmond Wong, Leonid Churilov, Jaishankar Raman, David J Clark, Omar Farouque

{"title":"Predicting severe multivessel coronary artery disease to guide access strategy in patients undergoing invasive coronary angiography.","authors":"Garry W Hamilton, David Chye, Hannah Johns, Jefferson Ko, Edmond Wong, Leonid Churilov, Jaishankar Raman, David J Clark, Omar Farouque","doi":"10.1097/MCA.0000000000001490","DOIUrl":"10.1097/MCA.0000000000001490","url":null,"abstract":"Introduction: Given radial artery conduits are increasingly utilized for coronary artery bypass grafting (CABG), avoiding transradial access (TRA) for invasive coronary angiography (ICA) may benefit patients who ultimately undergo CABG. We sought to predict the likelihood of severe multivessel disease (MVD) before ICA to guide this decision.Methods: This was a single-center study of 1485 patients with stable symptoms who underwent ICA. A model to predict severe MVD was developed. Relative importance analyses were performed to identify clinical characteristics most associated with the presence or absence of severe MVD.Results: When predicting severe MVD, the model had a sensitivity of 70.3% and specificity of 71.8% (area under the curve = 0.7105). With a prevalence of 12.5% in our cohort, the model had a strong negative predictive value of 94.4%. Relative importance analyses showed factors most associated with the presence of severe MVD were a history of abnormal noninvasive tests, typical chest pain, aspirin use, insulin-dependent diabetes, increasing age, and a family history of coronary artery disease. Conversely, the absence of severe MVD was most associated with female sex, undergoing ICA as workup for either noncardiac or valve surgery, lung disease, atypical chest pain, and increased BMI.Conclusion: Clinical information available before ICA can risk stratify the likelihood of severe MVD and therefore aid in identifying patients that may need CABG and could stand to benefit from TRA avoidance. The potential benefits of maximizing radial artery conduit availability by avoiding TRA must be balanced against the risks of alternative access on an individual patient basis.","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":"e12-e18"},"PeriodicalIF":2.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142845945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0