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Sessile Serrated Adenoma Plus Lipoid Pneumonia Mimicking a Colon Cancer With Pulmonary Metastatic Lesions on 18 F-FDG PET/CT. 18F-FDG PET/CT显示无柄锯齿状腺瘤合并脂质性肺炎模拟结肠癌伴肺转移灶。
IF 9.6 3区 医学
Clinical Nuclear Medicine Pub Date : 2025-09-01 Epub Date: 2025-06-06 DOI: 10.1097/RLU.0000000000005744
Paulo Schiavom Duarte, Rafael Dyer Rodrigues de Moraes, Euclides Antônio da Costa, Marcelo Tatit Sapienza, Carlos Alberto Buchpiguel
{"title":"Sessile Serrated Adenoma Plus Lipoid Pneumonia Mimicking a Colon Cancer With Pulmonary Metastatic Lesions on 18 F-FDG PET/CT.","authors":"Paulo Schiavom Duarte, Rafael Dyer Rodrigues de Moraes, Euclides Antônio da Costa, Marcelo Tatit Sapienza, Carlos Alberto Buchpiguel","doi":"10.1097/RLU.0000000000005744","DOIUrl":"10.1097/RLU.0000000000005744","url":null,"abstract":"<p><p>A 65-year-old man with a history of chronic cough presented with bilateral pulmonary masses identified on computed tomography. A 18 F-FDG PET/CT study demonstrated moderate uptake in the lung masses and unexpectedly intense uptake in a proximal transverse colonic lesion. While the initial interpretation suggested metastatic lung disease from colon cancer, subsequent colonoscopic resection of the colon lesion and biopsy of the lung lesions revealed a sessile serrated adenoma and lipoid pneumonia, respectively. The patient disclosed a history of mineral oil use for constipation.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":"e551-e552"},"PeriodicalIF":9.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144233451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Detection of the Cingulate Island Sign by Early Perfusion Imaging in Dopamine Transporter SPECT With Multiple-Pinhole Collimators. 多针孔准直多巴胺转运体SPECT早期灌注显像检测扣带岛征。
IF 9.6 3区 医学
Clinical Nuclear Medicine Pub Date : 2025-09-01 Epub Date: 2025-02-03 DOI: 10.1097/RLU.0000000000005700
Amir Karimzadeh, Anne Burkhardt, Susanne Klutmann, Ivayla Apostolova, Ralph Buchert
{"title":"Detection of the Cingulate Island Sign by Early Perfusion Imaging in Dopamine Transporter SPECT With Multiple-Pinhole Collimators.","authors":"Amir Karimzadeh, Anne Burkhardt, Susanne Klutmann, Ivayla Apostolova, Ralph Buchert","doi":"10.1097/RLU.0000000000005700","DOIUrl":"10.1097/RLU.0000000000005700","url":null,"abstract":"<p><strong>Abstract: </strong>Multiple-pinhole collimators provide considerable improvement of SPECT system count sensitivity. This case report suggests that SPECT with brain-specific multiple-pinhole collimators enables cerebral perfusion imaging with diagnostic quality by an early 12 minutes scan immediately after injection of a standard dose of the dopamine transporter ligand 123 I-FP-CIT. Thus, 123 I-FP-CIT SPECT with multiple-pinhole collimators could assess nigrostriatal degeneration (late image) and extrastriatal involvement (early perfusion image) during the same imaging session. The early image may serve as an alternative to FDG PET in patients with suspicion of an atypical neurodegenerative parkinsonian syndrome. This could streamline diagnostic workflows by reducing the need for additional imaging modalities.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":"871-872"},"PeriodicalIF":9.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143078593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Herpes Zoster-induced Ganglioneuritis With Corresponding Shingles Dermatome and Its Regression Within 10 Weeks Following 6 Cycles of BEACOPP Chemotherapy. 带状疱疹性神经节神经炎伴带状疱疹皮组及其在6个化疗周期后10周内的消退。
IF 9.6 3区 医学
Clinical Nuclear Medicine Pub Date : 2025-09-01 Epub Date: 2025-02-24 DOI: 10.1097/RLU.0000000000005785
Stephan Hilliger, Felix Schön, Robert Winzer, Karolin Trautmann-Grill, Sebastian Hoberück
{"title":"Herpes Zoster-induced Ganglioneuritis With Corresponding Shingles Dermatome and Its Regression Within 10 Weeks Following 6 Cycles of BEACOPP Chemotherapy.","authors":"Stephan Hilliger, Felix Schön, Robert Winzer, Karolin Trautmann-Grill, Sebastian Hoberück","doi":"10.1097/RLU.0000000000005785","DOIUrl":"10.1097/RLU.0000000000005785","url":null,"abstract":"<p><p>A 28-year-old man underwent FDG-PET/CT for Hodgkin lymphoma restaging after 6 cycles of BEACOPP chemotherapy. He had recently been diagnosed with herpes zoster, treated with antivirals, presenting with a painful rash on the right lower flank. The FDG PET scan revealed high focal FDG uptake in the right 11th spinal nerve ganglion and moderate diffuse uptake in the rash area. A follow-up scan after 10 weeks showed a complete regression of both findings. To the best of our knowledge, this is the first reported case of marked FDG-avid spinal ganglion indicating active ganglioneuritis and dermal herpes zoster, with complete regression on follow-up.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":"e556-e558"},"PeriodicalIF":9.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143482410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Focal Intense FDG Uptake of the Tongue Muscle Due to Repeated Tooth-Licking Mimicking Malignancy. 重复舔牙模仿恶性肿瘤引起的舌肌局灶性强烈FDG摄取。
IF 9.6 3区 医学
Clinical Nuclear Medicine Pub Date : 2025-09-01 Epub Date: 2025-02-13 DOI: 10.1097/RLU.0000000000005707
Yajing Huo, Aisheng Dong, Yan Han
{"title":"Focal Intense FDG Uptake of the Tongue Muscle Due to Repeated Tooth-Licking Mimicking Malignancy.","authors":"Yajing Huo, Aisheng Dong, Yan Han","doi":"10.1097/RLU.0000000000005707","DOIUrl":"10.1097/RLU.0000000000005707","url":null,"abstract":"<p><strong>Abstract: </strong>A 55-year-old woman underwent FDG PET/CT to detect possible multiple myeloma due to IgM κ paraproteinemia. FDG PET/CT showed a focal intense activity with SUV max of 21.3 in her anterior tongue, suspicious for malignancy. MRI and physical examination of the tongue were normal. On further inquiry, the patient reported she had a habit of licking her anterior mandibular teeth and licked her teeth repeatedly before and after injection of FDG. Consequently, the tongue activity was interpreted as physiological tongue muscle activity due to repeated tooth-licking.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":"878-879"},"PeriodicalIF":9.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143416701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multimodal Imaging Demonstrated a Case of Buccal Cancer Cardiac Metastases Treated With Immune Checkpoint Inhibitor Therapy. 多模态影像显示1例口腔癌心脏转移用免疫检查点抑制剂治疗。
IF 9.6 3区 医学
Clinical Nuclear Medicine Pub Date : 2025-09-01 Epub Date: 2025-04-02 DOI: 10.1097/RLU.0000000000005867
Chien-Cheng Wang, Hsueh-Ju Lu, Teng-Fu Tsao, Wun-Zhih Siao, Pan-Fu Kao
{"title":"Multimodal Imaging Demonstrated a Case of Buccal Cancer Cardiac Metastases Treated With Immune Checkpoint Inhibitor Therapy.","authors":"Chien-Cheng Wang, Hsueh-Ju Lu, Teng-Fu Tsao, Wun-Zhih Siao, Pan-Fu Kao","doi":"10.1097/RLU.0000000000005867","DOIUrl":"10.1097/RLU.0000000000005867","url":null,"abstract":"<p><p>A 35-year-old man with recurrent oral cancer underwent restaging FDG PET/CT imaging, which revealed neck lymph node metastasis and multiple distant metastases, including involvement of the right atrium, right ventricle, and pericardium. Doppler echocardiography and cardiac MRI confirmed the cardiac metastases while demonstrating preserved left ventricular systolic function. Follow-up FDG PET/CT imaging at 3 and 6 months after immune checkpoint inhibitor therapy, initiated due to high PD-L1 expression in the primary tumor, showed complete remission.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":"885-886"},"PeriodicalIF":9.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143771694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epicardial Metastases Causing Coronary Artery Compression and Myocardial Infarction on [ 18 F]FDG PET-CT. 心外膜转移引起冠状动脉压迫和心肌梗死[18F]FDG PET-CT。
IF 9.6 3区 医学
Clinical Nuclear Medicine Pub Date : 2025-09-01 Epub Date: 2025-04-11 DOI: 10.1097/RLU.0000000000005819
Joshua Wilcox, Ankur Gulati, Elias Pintus, Andrew D'Silva, Manil Subesinghe
{"title":"Epicardial Metastases Causing Coronary Artery Compression and Myocardial Infarction on [ 18 F]FDG PET-CT.","authors":"Joshua Wilcox, Ankur Gulati, Elias Pintus, Andrew D'Silva, Manil Subesinghe","doi":"10.1097/RLU.0000000000005819","DOIUrl":"10.1097/RLU.0000000000005819","url":null,"abstract":"<p><p>A 64-year-old woman with metastatic lung adenocarcinoma on immune checkpoint inhibitor (ICI) therapy suffered an acute coronary syndrome and underwent percutaneous coronary intervention (PCI). Despite PCI and anti-anginal therapy, she continued to experience angina. Cardiac magnetic resonance imaging (CMR) suggested a diagnosis of ICI myocarditis. However, refractory angina and non-resolving changes on CMR despite high-dose steroids prompted further evaluation with [ 18 F]FDG PET-CT; this yielded a final diagnosis of epicardial metastatic coronary artery compression with myocardial infarction. This case demonstrates the incremental diagnostic value of multimodality imaging in cardio-oncology.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":"856-858"},"PeriodicalIF":9.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143983306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnostic Performances of Radiolabeled FAPI PET/CT for Lymph Node Staging in Head and Neck Cancer Patients: Comparison With 18 F-FDG PET/CT. 放射标记FAPI PET/CT对头颈部肿瘤患者淋巴结分期的诊断价值：与18F-FDG PET/CT的比较
IF 9.6 3区 医学
Clinical Nuclear Medicine Pub Date : 2025-09-01 Epub Date: 2025-05-14 DOI: 10.1097/RLU.0000000000005973
Yun Seong Kim, Seong-Jang Kim
{"title":"Diagnostic Performances of Radiolabeled FAPI PET/CT for Lymph Node Staging in Head and Neck Cancer Patients: Comparison With 18 F-FDG PET/CT.","authors":"Yun Seong Kim, Seong-Jang Kim","doi":"10.1097/RLU.0000000000005973","DOIUrl":"10.1097/RLU.0000000000005973","url":null,"abstract":"<p><strong>Objective: </strong>The purpose of the current study was to compare the diagnostic performances of radiolabeled FAPI and 18 F-FDG PET/CT for the detection of lymph node (LN) metastasis in head and neck cancer (HNC) patients.</p><p><strong>Methods: </strong>The PubMed, Cochrane database, and EMBASE database, from the earliest available date of indexing through December 31, 2024, were searched for studies comparing diagnostic performances of radiolabeled FAPI and 18 F-FDG PET/CT for the detection of metastatic LN in HNC patients. We estimated pooled sensitivities and specificities across studies.</p><p><strong>Results: </strong>Across 8 studies (14 results), the pooled sensitivity of FAPI PET/CT was 0.89 and the pooled specificity was 0.93. The pooled sensitivity of 18 F-FDG PET/CT was 0.91 and the pooled specificity was 0.50. On patient-based analysis, the estimated sensitivity and specificity of FAPI were 0.96 and 0.96, and those of 18 F-FDG were 0.95 and 0.34, respectively. On lesion-based analysis, the estimated sensitivity and specificity of FAPI were 0.84 and 0.94, and those of 18 F-FDG were 0.86 and 0.78, respectively. On neck side-based analysis, the estimated sensitivity and specificity of FAPI were 0.88 and 0.79, and those of 18 F-FDG were 0.91 and 0.29, respectively.</p><p><strong>Conclusions: </strong>Radiolabeled FAPI showed a good diagnostic performance for the detection of metastatic LN in HNC patients. Also, 18 F-FDG PET/CT revealed low specificity for LN staging in HNC patients. Future large multicenter research with more patients would be necessary to provide a more comprehensive overview of the usefulness of radiolabeled FAPI for LN staging in HNC patients.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":"840-846"},"PeriodicalIF":9.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Primary Prostatic Synovial Sarcoma With Intravenous Tumor Thrombus Presented on 18 F-FDG and Al 18 F-Thretide PET/CT. 18F-FDG和al18f -三tide PET/CT显示原发性前列腺滑膜肉瘤伴静脉肿瘤血栓。
IF 9.6 3区 医学
Clinical Nuclear Medicine Pub Date : 2025-09-01 Epub Date: 2025-05-21 DOI: 10.1097/RLU.0000000000005886
Xin Cheng, Guozhu Hou, Shan Zheng, Yong Zhang, Xuejuan Wang
{"title":"Primary Prostatic Synovial Sarcoma With Intravenous Tumor Thrombus Presented on 18 F-FDG and Al 18 F-Thretide PET/CT.","authors":"Xin Cheng, Guozhu Hou, Shan Zheng, Yong Zhang, Xuejuan Wang","doi":"10.1097/RLU.0000000000005886","DOIUrl":"10.1097/RLU.0000000000005886","url":null,"abstract":"<p><p>A 35-year-old man with painful and difficult urination underwent 18 F-FDG and Al 18 F-Thretide PET/CT scans after a pelvic MRI suggested a prostate mass. The 18 F-FDG and Al 18 F-Thretide PET/CT scans revealed a prostate mass accompanied by an intravenous tumor thrombus. Both the prostate mass and the intravenous tumor thrombus demonstrated increased FDG uptake. Intense PSMA activity was observed in both lesions, with the intravenous tumor thrombus showing considerably higher PSMA activity compared with its FDG uptake. Histologic analysis of the biopsy confirmed the diagnosis of prostatic synovial sarcoma. PSMA immunohistochemistry showed high PSMA expression in the vascular endothelial cells within the tumor.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":"887-888"},"PeriodicalIF":9.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144110008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metastasis of Urothelial Carcinoma to the Wrist: A Case Report of an Overlooked Finding on Whole-body 99m Tc-MDP Scan. 尿路上皮癌转移至手腕：全身99mTc-MDP扫描一例被忽视的发现。
IF 9.6 3区 医学
Clinical Nuclear Medicine Pub Date : 2025-09-01 Epub Date: 2025-02-26 DOI: 10.1097/RLU.0000000000005719
Hamidreza Ghorbani, Amin Saber Tanha, Naime Ataei, Reza Ataei, Ali Zare
{"title":"Metastasis of Urothelial Carcinoma to the Wrist: A Case Report of an Overlooked Finding on Whole-body 99m Tc-MDP Scan.","authors":"Hamidreza Ghorbani, Amin Saber Tanha, Naime Ataei, Reza Ataei, Ali Zare","doi":"10.1097/RLU.0000000000005719","DOIUrl":"10.1097/RLU.0000000000005719","url":null,"abstract":"<p><p>A 65-year-old man presented with painless hematuria and a bladder mass, diagnosed as high-grade papillary urothelial carcinoma following transurethral resection. Considering negative metastasis workup, he was scheduled for radical cystectomy. During follow-up, he reported chronic wrist pain. A whole-body 99m Tc-Methylene diphosphonate (MDP) scan showed focal uptake in the wrist, misinterpreted as arthritis and overlooked as inconsequential. Three months later, x-ray imaging revealed a lytic wrist lesion, later confirmed as metastatic carcinoma through biopsy. Immunohistochemical analysis supported the diagnosis, highlighting the importance of careful interpretation of imaging findings in patients with bladder cancer.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":"e561-e563"},"PeriodicalIF":9.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143499588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
FDG PET/CT in a Case of Solid Papillary Carcinoma of the Breast. 乳腺实性乳头状癌1例FDG PET/CT分析。
IF 9.6 3区 医学
Clinical Nuclear Medicine Pub Date : 2025-09-01 Epub Date: 2025-03-05 DOI: 10.1097/RLU.0000000000005791
Jiani He, Aisheng Dong
{"title":"FDG PET/CT in a Case of Solid Papillary Carcinoma of the Breast.","authors":"Jiani He, Aisheng Dong","doi":"10.1097/RLU.0000000000005791","DOIUrl":"10.1097/RLU.0000000000005791","url":null,"abstract":"<p><p>Solid papillary carcinoma of the breast is a rare low-grade tumor of the breast with unique histology and frequent neuroendocrine differentiation. The tumor usually affects older women with a favorable prognosis. We describe FDG PET/CT findings in a patient with unilateral invasive solid papillary carcinoma of the breast with ipsilateral axillary lymph node metastasis. The primary breast tumor showed focal intense activity (SUV max , 8.8), and the enlarged metastatic axillary lymph node showed higher FDG uptake (SUV max , 17.8) than the primary tumor. This case indicates that FDG PET/CT may be useful for staging this rare tumor, which needs further investigation.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":"880-882"},"PeriodicalIF":9.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143556183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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