多针孔准直多巴胺转运体SPECT早期灌注显像检测扣带岛征。

IF 9.6 3区 医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Clinical Nuclear Medicine Pub Date : 2025-09-01 Epub Date: 2025-02-03 DOI:10.1097/RLU.0000000000005700
Amir Karimzadeh, Anne Burkhardt, Susanne Klutmann, Ivayla Apostolova, Ralph Buchert
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引用次数: 0

摘要

摘要:多针孔准直器大大提高了SPECT系统的计数灵敏度。本病例报告表明,在注射标准剂量的多巴胺转运体配体123I-FP-CIT后,使用脑特异性多针孔准直器的SPECT可以在早期12分钟扫描后立即进行具有诊断质量的脑灌注成像。因此,采用多针孔准直器的123I-FP-CIT SPECT可以在同一成像过程中评估黑质纹状体变性(晚期图像)和纹状体外受累(早期灌注图像)。早期图像可作为替代FDG PET在怀疑非典型神经退行性帕金森综合征的患者。这可以通过减少对额外成像方式的需求来简化诊断工作流程。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Detection of the Cingulate Island Sign by Early Perfusion Imaging in Dopamine Transporter SPECT With Multiple-Pinhole Collimators.

Abstract: Multiple-pinhole collimators provide considerable improvement of SPECT system count sensitivity. This case report suggests that SPECT with brain-specific multiple-pinhole collimators enables cerebral perfusion imaging with diagnostic quality by an early 12 minutes scan immediately after injection of a standard dose of the dopamine transporter ligand 123 I-FP-CIT. Thus, 123 I-FP-CIT SPECT with multiple-pinhole collimators could assess nigrostriatal degeneration (late image) and extrastriatal involvement (early perfusion image) during the same imaging session. The early image may serve as an alternative to FDG PET in patients with suspicion of an atypical neurodegenerative parkinsonian syndrome. This could streamline diagnostic workflows by reducing the need for additional imaging modalities.

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来源期刊
Clinical Nuclear Medicine
Clinical Nuclear Medicine 医学-核医学
CiteScore
2.90
自引率
31.10%
发文量
1113
审稿时长
2 months
期刊介绍: Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.
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