Multimodal Imaging Demonstrated a Case of Buccal Cancer Cardiac Metastases Treated With Immune Checkpoint Inhibitor Therapy.

IF 9.6 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Nuclear Medicine Pub Date : 2025-09-01 Epub Date: 2025-04-02 DOI:10.1097/RLU.0000000000005867

Chien-Cheng Wang, Hsueh-Ju Lu, Teng-Fu Tsao, Wun-Zhih Siao, Pan-Fu Kao

引用次数: 0

Abstract

A 35-year-old man with recurrent oral cancer underwent restaging FDG PET/CT imaging, which revealed neck lymph node metastasis and multiple distant metastases, including involvement of the right atrium, right ventricle, and pericardium. Doppler echocardiography and cardiac MRI confirmed the cardiac metastases while demonstrating preserved left ventricular systolic function. Follow-up FDG PET/CT imaging at 3 and 6 months after immune checkpoint inhibitor therapy, initiated due to high PD-L1 expression in the primary tumor, showed complete remission.

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多模态影像显示1例口腔癌心脏转移用免疫检查点抑制剂治疗。

一名35岁男性口腔癌复发患者行FDG PET/CT复诊，发现颈部淋巴结转移及多发远处转移，包括累及右心房、右心室和心包。多普勒超声心动图和心脏MRI证实心脏转移，同时显示左心室收缩功能保留。在免疫检查点抑制剂治疗后3个月和6个月的随访FDG PET/CT成像显示完全缓解，由于原发肿瘤中PD-L1的高表达而开始。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Nuclear Medicine 医学-核医学

CiteScore

2.90

自引率

31.10%

发文量

1113

审稿时长

2 months

期刊介绍： Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.