Epicardial Metastases Causing Coronary Artery Compression and Myocardial Infarction on [ 18 F]FDG PET-CT.

IF 9.6 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Nuclear Medicine Pub Date : 2025-09-01 Epub Date: 2025-04-11 DOI:10.1097/RLU.0000000000005819

Joshua Wilcox, Ankur Gulati, Elias Pintus, Andrew D'Silva, Manil Subesinghe

引用次数: 0

Abstract

A 64-year-old woman with metastatic lung adenocarcinoma on immune checkpoint inhibitor (ICI) therapy suffered an acute coronary syndrome and underwent percutaneous coronary intervention (PCI). Despite PCI and anti-anginal therapy, she continued to experience angina. Cardiac magnetic resonance imaging (CMR) suggested a diagnosis of ICI myocarditis. However, refractory angina and non-resolving changes on CMR despite high-dose steroids prompted further evaluation with [ 18 F]FDG PET-CT; this yielded a final diagnosis of epicardial metastatic coronary artery compression with myocardial infarction. This case demonstrates the incremental diagnostic value of multimodality imaging in cardio-oncology.

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心外膜转移引起冠状动脉压迫和心肌梗死[18F]FDG PET-CT。

一名64岁的女性转移性肺腺癌患者在接受免疫检查点抑制剂（ICI）治疗后出现急性冠状动脉综合征，并接受了经皮冠状动脉介入治疗（PCI）。尽管进行了PCI治疗和抗心绞痛治疗，她仍然感到心绞痛。心脏磁共振成像（CMR）提示ICI心肌炎。然而，尽管使用大剂量类固醇，难治性心绞痛和CMR未解决的变化促使FDG PET-CT进一步评估[18F]；最终诊断为心外膜转移性冠状动脉压迫合并心肌梗死。本病例证明了多模态成像在心脏肿瘤学中的增量诊断价值。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Nuclear Medicine 医学-核医学

CiteScore

2.90

自引率

31.10%

发文量

1113

审稿时长

2 months

期刊介绍： Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.