Compounds最新文献_第7页

Polyphenols in Health and Disease: Gut Microbiota, Bioaccessibility, and Bioavailability 健康和疾病中的多酚:肠道微生物群，生物可及性和生物利用度

Compounds Pub Date : 2023-01-05 DOI: 10.3390/compounds3010005

Joaquim Bié, B. Sepodes, Pedro C. B. Fernandes, M. Ribeiro

引用次数: 24

Two Years of Life for a New Journal: Compounds 新期刊的两年生命:化合物

Compounds Pub Date : 2023-01-03 DOI: 10.3390/compounds3010004

J. Mejuto

引用次数: 0

Recent Progress in the Theoretical Studies of the Noncovalent Interactions of Supramolecular Complexes with Polyhalides and Halometalates 多卤化物和金属卤盐超分子配合物非共价相互作用的理论研究进展

Compounds Pub Date : 2022-12-30 DOI: 10.3390/compounds3010003

A. Novikov

引用次数: 0

Facile Synthesis of Pyrrolyl-Containing Semisquaraines in Water as Precursors for Non-Symmetric Squaraines 非对称方烷前体含吡咯基半方烷在水中的简易合成

Compounds Pub Date : 2022-12-28 DOI: 10.3390/compounds3010002

Daniel D. Ta, Jeanne M. Favret, S. Dzyuba

引用次数: 0

Compound Characterization of a Mucuna Seed Extract: L-Dopa, Arginine, Stizolamine, and Some Fructooligosaccharides 一种粘豆籽提取物的化合物表征:左旋多巴、精氨酸、史替唑胺和一些低聚果糖

Compounds Pub Date : 2022-12-27 DOI: 10.3390/compounds3010001

A. L. Hernández-Orihuela, Karla V. Castro-Cerritos, Mercedes G. López, A. Martínez-Antonio

{"title":"Compound Characterization of a Mucuna Seed Extract: L-Dopa, Arginine, Stizolamine, and Some Fructooligosaccharides","authors":"A. L. Hernández-Orihuela, Karla V. Castro-Cerritos, Mercedes G. López, A. Martínez-Antonio","doi":"10.3390/compounds3010001","DOIUrl":"https://doi.org/10.3390/compounds3010001","url":null,"abstract":"Human societies demand sustainable alternatives for goods and services. Plants are sustainable sources of important metabolites with beneficial impacts on human health. There are many reported methodologies and commercial suppliers for extract preparations from Mucuna sp. They usually claim the plant is enriched with L-dopa, its distinctive metabolite. However, many present poor characterizations of the extract’s components. Here, we present polar metabolites characterization of a Mucuna seed extract, emphasizing L-dopa identification and quantification. To obtain the extracts, we follow a green and sustainable extraction protocol. The lyophilized extract is subjected to liquid chromatography and mass spectrometry to identify its primary metabolites. Additionally, we follow thin-layer chromatography to identify carbohydrates in the sample. The resultant extract has 56% L-dopa. Other main components in the extract are arginine, stizolamine, and the fructooligosaccharides sucrose and nystose. The characterized Mucuna extract can be easily standardized using powder preparation and used in several biomedical applications.","PeriodicalId":10621,"journal":{"name":"Compounds","volume":"202 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78948284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Protection and Rehabilitation Effects of Cordyceps militaris Fruit Body Extract and Possible Roles of Cordycepin and Adenosine 蛹虫草子实体提取物的保护和康复作用及虫草素和腺苷的可能作用

Compounds Pub Date : 2022-12-19 DOI: 10.3390/compounds2040032

M. Bach, T. N. Minh, D. Anh, Hoang Ngoc Anh, Le Viet Anh, N. Q. Trung, Bui Quang Minh, T. Xuan

{"title":"Protection and Rehabilitation Effects of Cordyceps militaris Fruit Body Extract and Possible Roles of Cordycepin and Adenosine","authors":"M. Bach, T. N. Minh, D. Anh, Hoang Ngoc Anh, Le Viet Anh, N. Q. Trung, Bui Quang Minh, T. Xuan","doi":"10.3390/compounds2040032","DOIUrl":"https://doi.org/10.3390/compounds2040032","url":null,"abstract":"Cordyceps militaris is a valued medicinal fungus in folk medicine in East Asia. It contains two major nucleosides, cordycepin and adenosine, which have been reported to have potential antineoplastic, antioxidant, and anti-inflammatory activities. This paper aimed to study the effect of C. militaris extract on the reproductive function of a mouse model, evaluating possible toxicity, androgenic activity, and protective and rehabilitative effects against damages caused by sodium valproate (VPA). There was no death and abnormalities observed in mice. Androgen activity was also shown in young male rats by an improvement in several sexual organs. The protective effect of C. militaris extract was explained by the gain of sexual organs’ weight, testosterone concentration, and seminiferous tubule size as well as the enhancement of sperm density, alive sperm percentage, and the progressive forward movement of sperm. The pregnancy rate of female rats paired with VPA-administered male rats (500 mg/kg/day) increased proportionally with the higher dose of C. militaris extract. In the rehabilitation study, an incline in the weight of the Cowper’s gland and glans (0.112 g/kg/day) and testicle and prostate (0.336 g/kg/day) as well as an improvement of the sperm forward progressive movement was observed. The percentage of unprogressive sperm and immotile sperm has reduced. These results suggest that C. militaris is a potential supplement to reduce the negative effects of VPA and improve reproductive function, in which the two major constituents cordycepin and adenosine may play an active role.","PeriodicalId":10621,"journal":{"name":"Compounds","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75975747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Perovskite-Type Oxide Catalysts in CO2 Utilization: A Principal Study of Novel Cu-Doped Perovskites for Methanol Synthesis 钙钛矿型氧化物催化剂在CO2利用中的应用:新型cu掺杂钙钛矿甲醇合成的主要研究

Compounds Pub Date : 2022-12-14 DOI: 10.3390/compounds2040031

F. Schrenk, L. Lindenthal, Gernot Pacholik, Tina Navratil, Tobias Maximilian Berger, H. Drexler, R. Rameshan, T. Ruh, K. Föttinger, C. Rameshan

{"title":"Perovskite-Type Oxide Catalysts in CO2 Utilization: A Principal Study of Novel Cu-Doped Perovskites for Methanol Synthesis","authors":"F. Schrenk, L. Lindenthal, Gernot Pacholik, Tina Navratil, Tobias Maximilian Berger, H. Drexler, R. Rameshan, T. Ruh, K. Föttinger, C. Rameshan","doi":"10.3390/compounds2040031","DOIUrl":"https://doi.org/10.3390/compounds2040031","url":null,"abstract":"Six different perovskite-type oxides were investigated with respect to their ability for methanol synthesis via H2 and CO2: Fe-, Mn-, and Ti-based perovskites were prepared with and without Cu doping. For assessment, the catalysts were subjected to preliminary tests at atmospheric pressure to evaluate their ability to activate CO2. Additional catalytic tests with the doped versions of each catalyst type were carried out in a pressured reactor at 21 bar. After the measurements, the catalysts were characterized with X-ray diffraction (XRD) and scanning electron microscopy (SEM). All catalysts were able to produce methanol in the pressure tests. CO2 conversions between 14% and 23% were reached at 400 °C, with the highest methanol selectivity at the lower temperature of 250 °C. The combination of XRD and SEM revealed that the Fe-based and Ti-based perovskites were stable under reaction conditions and that catalytically highly active and stable nanoparticles had formed. The minor formation of CaCO3, which is a deactivating phase, was observed for one catalyst. These nanoparticles showed resistance to coking and sintering. However, the yield and selectivity for methanol need to be improved via the further tailoring of the perovskite composition.","PeriodicalId":10621,"journal":{"name":"Compounds","volume":"75 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88174140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Particles in the Eluate from Double Filtration Plasmapheresis—A Case Study Using Field Emission Scanning Electron Microscopy/Energy-Dispersive X-ray Spectroscopy (FE-SEM/EDX) 双滤浆分离洗脱液中的颗粒——场发射扫描电镜/能量色散x射线能谱(FE-SEM/EDX)研究

Compounds Pub Date : 2022-12-01 DOI: 10.3390/compounds2040030

F. Scholkmann, A. Gatti

引用次数: 0

Preparation and Characterizations of Curcumin Protection and Delivery System Using Linear Dextrin 线性糊精姜黄素保护递送体系的制备与表征

Compounds Pub Date : 2022-11-16 DOI: 10.3390/compounds2040029

Huifang Xie, Litao Ma, Yanan Li, Junqing Fu, Zhongxian Li, Xuejun Yu, Qunyu Gao

{"title":"Preparation and Characterizations of Curcumin Protection and Delivery System Using Linear Dextrin","authors":"Huifang Xie, Litao Ma, Yanan Li, Junqing Fu, Zhongxian Li, Xuejun Yu, Qunyu Gao","doi":"10.3390/compounds2040029","DOIUrl":"https://doi.org/10.3390/compounds2040029","url":null,"abstract":"In this work, linear dextrins (LDs) with the fragment F-40 (DP = 31.44) were fabricated from waxy potato starch through pasteurization and enzymatic debranching by pullulanase and then separated and extracted by ethanol solutions with different concentrations. The LDs were used to encapsulate hydrophobic ligand curcumin to develop a controlled release system that would increase its flavor in food and functions in medicines. The physicochemical properties and the encapsulation mechanism of the inclusion complexes were investigated. It was found that the loading capability for curcumin, the encapsulation rate, and the yield of the complexes depended on the molecular weight of LD. The yield of the LD-Cur complex, its encapsulation rate, and loading of curcumin were 19.86%, 25.81%, and 29.52 μg/mg, respectively, while the yield of the F-40-Cur complex, its inclusion rate, and loading curcumin reached up to 75.98%, 29.97%, and 37.52 μg/mg, respectively. There were both hydrogen bonding and hydrophobic interactions between LD and curcumin, while hydrogen bonding interactions were predominant between F-40 and curcumin. Curcumin was presented in the complex in an amorphous form. The photothermal stability of curcumin increased after being complexed with LD and further enhanced significantly with F-40. The release of curcumin in the intestine was achieved much more effectively.","PeriodicalId":10621,"journal":{"name":"Compounds","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91079924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Possible Role of Vesicles on Metallocatalytic Reduction Reaction of 5-Hydroxymethylfurfural to 2,5-Dimethylfuran 囊泡在5-羟甲基糠醛金属催化还原反应中可能的作用

Compounds Pub Date : 2022-11-03 DOI: 10.3390/compounds2040027

T. Shimanouchi, Y. Takahashi, Keita Hayashi, K. Yasuhara, Y. Kimura

引用次数: 2