Compounds最新文献_第6页

Antioxidant and UV-Blocking Functionalized Poly(Butylene Succinate) Films 抗氧化和抗紫外线功能化聚琥珀酸丁二烯薄膜

Compounds Pub Date : 2023-02-09 DOI: 10.3390/compounds3010015

S. Coiai, N. Migliore, E. Passaglia, R. Spiniello, C. Gambarotti, F. Cicogna

{"title":"Antioxidant and UV-Blocking Functionalized Poly(Butylene Succinate) Films","authors":"S. Coiai, N. Migliore, E. Passaglia, R. Spiniello, C. Gambarotti, F. Cicogna","doi":"10.3390/compounds3010015","DOIUrl":"https://doi.org/10.3390/compounds3010015","url":null,"abstract":"The introduction of a limited number of functional groups on poly(butylene succinate) (PBS) chains by covalent bonding can impart new properties to the polymer without modifying its thermal and mechanical properties. In pursuit of a viable approach to obtain light- and heat-stabilized PBS samples, the nitroxide radical coupling (NRC) reaction between PBS macroradicals and the 3,5-di-tert-butyl-4-hydroxybenzoyl-2,2,6,6-tetramethylpiperidine-1-oxyl radical (BHB-TEMPO), a functionalizing agent bearing a sterically-hindered antioxidant phenol moiety, is here proposed. The reaction was initiated by peroxide and carried out in solution and in a melt. The functionalized materials were characterized by UV-visible spectroscopy (UV-Vis), proton nuclear magnetic resonance (1H-NMR), and size exclusion chromatography (SEC) analysis to gain structural information and by thermal gravimetric analysis (TGA) and differential scanning calorimetry (DSC) to investigate the thermal properties. In addition, films of the samples were subjected to thermal and photo-oxidative aging to assess their resistance to degradative processes. Finally, the PBS film with the highest degree of functionalization showed the ability to protect β-carotene, a molecule found in food and drugs and that is very sensitive to UV light, from degradation. This result suggests the use of this material (either alone or blended with other biopolyesters) for biodegradable and compostable active packaging.","PeriodicalId":10621,"journal":{"name":"Compounds","volume":"64 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90357115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reduction of the Plasma Uric Acid Level in Potassium Oxoate-Induced Hyperuricemic Rats by Heat-Concentrated Prunus mume Fruit Extract Containing Three Chlorogenic Acid Isomers 含三种绿原酸异构体的热浓缩梅子提取物降低氧化钾诱导的高尿酸血症大鼠血浆尿酸水平

Compounds Pub Date : 2023-02-08 DOI: 10.3390/compounds3010014

Yi-Ching Wu, P. Kuo, Wen-Ying Chen, J. Tzen

{"title":"Reduction of the Plasma Uric Acid Level in Potassium Oxoate-Induced Hyperuricemic Rats by Heat-Concentrated Prunus mume Fruit Extract Containing Three Chlorogenic Acid Isomers","authors":"Yi-Ching Wu, P. Kuo, Wen-Ying Chen, J. Tzen","doi":"10.3390/compounds3010014","DOIUrl":"https://doi.org/10.3390/compounds3010014","url":null,"abstract":"Gout is a common rheumatic disease, resulting from hyperuricemia. Prunus mume fruit extract, after being heat-concentrated named mei extract, was empirically found to reduce the risk of gout. While neochlorogenic acid was found as the predominant phenolic compound in the fresh juice of Prunus mume, neochlorogenic acid, chlorogenic acid, and cryptogenic acid were detected as the major phenolic compounds in the mei extract. In vitro testing showed that all the three chlorogenic acid isomers exhibited comparable inhibitory activities on xanthine oxidase. The hypouricemic effects of the mei extract were evaluated in potassium oxonate-induced hyperuricemic rats. Oral administrations of the mei extract significantly reduced the plasma uric acid level in hyperuricemic rats, but did not elevate the urinary uric acid level. The results provide in vivo evidence for the anti-hyperuricemic effects of mei extract for the first time, rationalize its therapeutic usage for the treatment of hyperuricemia and gout, and propose chlorogenic acid isomers as the active ingredients. Mei extract seems to be a potential natural functional food product.","PeriodicalId":10621,"journal":{"name":"Compounds","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81555749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fluorinated Merophosphinine and Phosphinine Dyes: Synthesis and Evaluation of UV-Visible Light Absorption Properties 氟化甲基膦和膦染料的合成及紫外-可见光吸收性能评价

Compounds Pub Date : 2023-02-02 DOI: 10.3390/compounds3010013

S. Yamada, Yusuke Takahashi, T. Konno

{"title":"Fluorinated Merophosphinine and Phosphinine Dyes: Synthesis and Evaluation of UV-Visible Light Absorption Properties","authors":"S. Yamada, Yusuke Takahashi, T. Konno","doi":"10.3390/compounds3010013","DOIUrl":"https://doi.org/10.3390/compounds3010013","url":null,"abstract":"Merophosphinine and phosphinine dyes were reported as phosphorus atom equivalents of merocyanine and cyanine dyes in the 1960s. Although these dyes are excellent sensitizers for enhancing photographic performance, their development has been considerably retarded because of difficulties in the synthetic process. Previously, while investigating the reactivity of fluoroalkenes with various nucleophiles, we developed fluorinated merophosphinine and phosphinine scaffolds in a single reaction step; however, we did not investigate their ultraviolet-visible (UV-vis) light absorption properties further. Therefore, in this study, we synthesized fluorinated merophosphinines and phosphinine derivatives using triphenylphosphonium ylides with various R substituents [R = H, C6H5, 4-MeOC6H4, 4-PhC6H4, or C6F5] and octafluorocyclopentene to study their absorption characteristics. Thermogravimetric analyses (TGA) indicated that several synthesized derivatives were thermally stable at temperatures above 241 °C. Additionally, when studied in various solvents, the fluorinated merophosphinine and phosphinine dyes exhibited well-defined maximum absorption wavelengths (λabs) in the 364–375 and 420–474 nm ranges, respectively. Thus, fluorinated merophosphinine and phosphinine derivatives may serve as promising thermally stable functional dyes for future technical applications.","PeriodicalId":10621,"journal":{"name":"Compounds","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73896001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Volatile Constituents and Antimicrobial Activity of Naio (Myoporum Sandwicense A. Gray), a Native Hawaiian Tree 夏威夷土生树Naio (Myoporum sandwich ense a . Gray)挥发性成分及抗菌活性研究

Compounds Pub Date : 2023-01-29 DOI: 10.3390/compounds3010012

Noura Sayed Dosoky, P. Satyal, A. Sorensen, W. Setzer

{"title":"Volatile Constituents and Antimicrobial Activity of Naio (Myoporum Sandwicense A. Gray), a Native Hawaiian Tree","authors":"Noura Sayed Dosoky, P. Satyal, A. Sorensen, W. Setzer","doi":"10.3390/compounds3010012","DOIUrl":"https://doi.org/10.3390/compounds3010012","url":null,"abstract":"Myoporum sandwicense A. Gray (naio) is one of the characteristic trees of Hawaiian montane–subalpine mesic forests. In this study, lab-distilled oils of M. sandwicense leaves, wood, and twigs growing on the island of Hawaii, as well as industrially produced wood oils, were characterized by gas chromatography–mass spectrometry (GC-MS). The lab-distilled oils were screened for antimicrobial activity. M. sandwicense leaf essential oil was rich in β-caryophyllene (15.1%), α-humulene (12.8%), germacrene D (7.9%), bicyclogermacrene (12.5%), brigalow ketol (9.6%), and myoporone (16.8%), while the wood essential oils were dominated by α-bisabolol and trans-α-bisabolol oxide B. The sapwood oil was dominated by palmitic acid (35.5%), linoleic acid (19.7%), oleic acid (31.9%), and stearic acid (5.7%), whereas the oil from twigs was rich in tricosane (77.3%) and pentacosane (13.1%). M. sandwicense essential oils were screened for antimicrobial activity against a panel of potentially pathogenic bacteria and fungi. The leaf essential oil of M. sandwicense showed excellent antibacterial activity against S. pyogenes and antifungal activity against A. fumigatus. The wood essential oil showed notable activity against S. pyogenes, A. fumigatus, A. niger, and M. gypseum. The twig oil was remarkably active against mold species. This work is the first report we are aware of on the composition and antimicrobial properties of naio essential oils.","PeriodicalId":10621,"journal":{"name":"Compounds","volume":"43 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83695584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Active Ingredients and Carriers in Nutritional Eco-Cosmetics 营养生态化妆品中的活性成分及载体

Compounds Pub Date : 2023-01-20 DOI: 10.3390/compounds3010011

P. Morganti, Alka Lohani, A. Gagliardini, G. Morganti, M. Coltelli

{"title":"Active Ingredients and Carriers in Nutritional Eco-Cosmetics","authors":"P. Morganti, Alka Lohani, A. Gagliardini, G. Morganti, M. Coltelli","doi":"10.3390/compounds3010011","DOIUrl":"https://doi.org/10.3390/compounds3010011","url":null,"abstract":"Beauty and personal care became a significant part of the global economy for two reasons: (1) The elderly growing in the global population and (2) the desire of women and men to appear younger and more attractive. Thus, both young and old people are looking for revolutionary nutritional eco-cosmetics (combined use of cosmeceuticals and nutraceuticals) manufactured by natural active ingredients, using biopolymers as substrates, and made by innovative and sustainable technologies. Consequently, the market of both cosmetics and diet supplements is continually growing together with the request of natural active ingredients, including bio-peptides and biological macromolecules such as chitin and lignin. Therefore, both consumers and industry need to recover innovative active ingredients and carriers (vehicles), naturally derived and supported by advanced methods for controlling their effectiveness and safeness on skin and mucous membrane layers. The use of selected bio-ingredients, such as hyaluronic acid and bio-mimetic peptides, obtained by advanced, innovative and sustainable bio nanotechnologies, will be of interest to develop smart cosmeceutical and nutraceutical formulations. Innovation is considered the key business strategy to drive sustainable economic growth. For trying to reduce waste and produce sustainable, biodegradable and innovative products, the realization of new non-woven tissues, used as carriers for making innovative cosmeceuticals and nutraceuticals was considered. Both carriers and active ingredients have been obtained from food waste to reduce loss and pollution. This review will report a brief description of the skin functions, trying also to focus and discuss some of the active ingredients and carriers used in nutritional eco-cosmetics to clarify the supposed mechanism of action, effectiveness and safeness of both active ingredients and carriers, as well as the supposed activity of beauty and personal care products.","PeriodicalId":10621,"journal":{"name":"Compounds","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75272659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Synthesis and Predicted Activity of Some 4-Amine and 4-(α-Aminoacid) Derivatives of N-Expanded-metronidazole Analogues n -扩展甲硝唑类似物的4-胺和4-(α-氨基酸)衍生物的合成及活性预测

Compounds Pub Date : 2023-01-19 DOI: 10.3390/compounds3010009

Justyna Żwawiak, L. Zaprutko

引用次数: 0

Ageladine A, a Bromopyrrole Alkaloid from the Marine Sponge Agelas nakamurai Ageladine A，一种溴吡咯生物碱，取自海绵中村Agelas

Compounds Pub Date : 2023-01-19 DOI: 10.3390/compounds3010010

George E. Magoulas

引用次数: 0

Acknowledgment to the Reviewers of Compounds in 2022 对2022年化合物审稿人的感谢

Compounds Pub Date : 2023-01-17 DOI: 10.3390/compounds3010008

引用次数: 0

Reduction Potential Predictions for Thirty-Seven 1,4-di-N-Oxide Quinoxaline-2-Carboxamide Derivatives with Anti-Tuberculosis Activity 37种具有抗结核活性的1,4-二n -氧化物喹啉-2-羧酰胺衍生物的还原潜力预测

Compounds Pub Date : 2023-01-13 DOI: 10.3390/compounds3010007

Faranak Pooladian, P. W. Crawford, Jonathan M. Kessler, Garrett R. Casey, Christina M. Ragain

引用次数: 1

Caryophyllene-Rich Essential Oils of Two Species from Southern Côte d’Ivoire: Guibourtia ehie (A. Chev.) J Léonard (Caesalpiniaceae) and Oricia suaveolens (Engl.) Verd. (Rutaceae)

Compounds Pub Date : 2023-01-12 DOI: 10.3390/compounds3010006

Toffé Alexis Kouao, Z. Ouattara, D. A. Kambiré, B. Kouamé, J. A. Mamyrbékova-Békro, P. Tomi, M. Paoli, A. Bighelli, Y. Bekro, F. Tomi

{"title":"Caryophyllene-Rich Essential Oils of Two Species from Southern Côte d’Ivoire: Guibourtia ehie (A. Chev.) J Léonard (Caesalpiniaceae) and Oricia suaveolens (Engl.) Verd. (Rutaceae)","authors":"Toffé Alexis Kouao, Z. Ouattara, D. A. Kambiré, B. Kouamé, J. A. Mamyrbékova-Békro, P. Tomi, M. Paoli, A. Bighelli, Y. Bekro, F. Tomi","doi":"10.3390/compounds3010006","DOIUrl":"https://doi.org/10.3390/compounds3010006","url":null,"abstract":"The essential oils of Oricia suaveolens and Guibourtia ehie from Southern Côte d’Ivoire were extracted by hydrodistillation then analyzed by gas chromatography in combination with retention indices [GC(RI)], gas chromatography coupled with mass spectrometry (GC-MS) and nuclear magnetic resonance of carbone-13 (13C NMR) And described here for the first time. A total of 42 compounds were identified in the essential oils of the leaves of G. ehie while 55, 40 and 23 components were identified in the leaves, stem bark and root bark oils of O. suaveolens, respectively. Essential oils samples were dominated by sesquiterpenes and (E)-β-caryophyllene was the major compound common to all samples: G. ehie leaf oil contained (E)-β-caryophyllene (26.9–40.8%), α-humulene (syn. α-caryophyllene) (6.7–9.7%), β-elemene (5.5–9.5%) and germacrene D (5.6–8.1%); O. suaveolens, leaf oil contained (E)-β-caryophyllene (33.5–39.3%), (E)-β-farnesene (5.9–9,3%), caryophyllene oxide (2.1–7.7%) and α-humulene (4.0–4.6%); stem bark oil contained α-humulene (38.3–45.8%) and (E)-β-caryophyllene (34.7–41.6%); root bark oil contained α-humulene (36.1–47.9%) and (E)-β-caryophyllene (34.3–43.3%). This study highlighted the abundant presence of (E)-β-caryophyllene, a phytocannabinoïd sesquiterpene with countless biological properties, in two plant species: Guibourtia ehie and Oricia suaveolens.","PeriodicalId":10621,"journal":{"name":"Compounds","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85344754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0