Compounds Pub Date : 2024-07-08 DOI: 10.3390/compounds4030028

Sofya Efimova, F. Lazar, J. Chopart, François Debray, A. Daltin

引用次数: 0

The Role of Bioactive Glasses in Dental Erosion―A Narrative Review 生物活性玻璃在牙齿腐蚀中的作用--叙述性综述

Compounds Pub Date : 2024-07-02 DOI: 10.3390/compounds4030027

D. Dionysopoulos

{"title":"The Role of Bioactive Glasses in Dental Erosion―A Narrative Review","authors":"D. Dionysopoulos","doi":"10.3390/compounds4030027","DOIUrl":"https://doi.org/10.3390/compounds4030027","url":null,"abstract":"Dental erosion represents the gradual and irreversible depletion of dental hard tissues due to a chemical process, independent of bacterial influence. It has emerged as a notable clinical concern in recent years, primarily attributed to substantial lifestyle shifts resulting in the heightened intake and frequency of acid-containing foods and beverages. Apart from the extrinsic erosive agents derived from external sources, such as dietary habits or medication, intrinsic erosive agents may exist due to pathological reasons with the contents of the stomach including gastric juice, mainly composed of hydrochloric acid, being their sole source. Currently, bioactive materials are used in various forms for the prevention of dental erosion. Such materials include, among others, bioactive glasses (BAGs). BAGs are a type of glass that, when in contact with biological fluids, can elicit a specific biological response. When they come into contact with bodily fluids, they can initiate a series of processes, including the formation of a hydroxyapatite layer on the glass surface. This bioactivity is particularly advantageous in medical and dental applications, where BAGs are used for bone regeneration, tissue repair, and dental restorative or preventive techniques. The aim of this literature review was to analyze and discuss the role of BAGs in protecting the tooth structures from dental erosion. The analysis of the existing literature regarding this topic indicated that the use of BAGs in preventive treatments against tooth erosion can be useful in dental practice. Further clinical evidence is necessary to confirm the effectiveness of the particular preventive measures.","PeriodicalId":10621,"journal":{"name":"Compounds","volume":"319 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141686670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Determination of Volatile Organic Compounds in Some Epipactis, Neottia, and Limodorum Orchids Growing in Basilicata (Southern Italy) 测定生长在巴西利卡塔（意大利南部）的一些 Epipactis、Neottia 和 Limodorum 兰花中的挥发性有机化合物

Compounds Pub Date : 2024-06-10 DOI: 10.3390/compounds4020022

Maurizio D’Auria, R. Lorenz, R. Racioppi, V. Romano

引用次数: 0

Anti-Inflammatory and Antithrombotic Potential of Metal-Based Complexes and Porphyrins 金属络合物和卟啉的抗炎和抗血栓潜力

Compounds Pub Date : 2024-06-10 DOI: 10.3390/compounds4020023

A. Tsoupras, Sofia Pafli, Charilaos Stylianoudakis, K. Ladomenou, C. Demopoulos, A. Philippopoulos

{"title":"Anti-Inflammatory and Antithrombotic Potential of Metal-Based Complexes and Porphyrins","authors":"A. Tsoupras, Sofia Pafli, Charilaos Stylianoudakis, K. Ladomenou, C. Demopoulos, A. Philippopoulos","doi":"10.3390/compounds4020023","DOIUrl":"https://doi.org/10.3390/compounds4020023","url":null,"abstract":"Inflammation and thrombosis are implicated in several chronic disorders. Recent studies have outlined the way in which several compounds can offer protection against inflammation. Within this comprehensive review the so-far reported anti-inflammatory health-promoting effects of several metal-based complexes, both in vitro and in vivo, are thoroughly presented. These metal-based compounds usually interfere with various biochemical processes associated with the inflammatory response and thrombus formation and become capable of inhibiting these biochemical pathways with proposed health benefits. Emphasis is given to the multifaceted actions of metal-based complexes that have exhibited potent anti-inflammatory and antithrombotic activities against the inflammatory mediator, platelet-activating factor (PAF), and its thrombo-inflammatory signaling, as well as on their anti-platelet and antitumor health promoting properties. Furthermore, the enhancement of the anti-inflammatory potency of well-established bioactive compounds by their incorporation as ligands in several metal-based complexes is discussed. Metal-based complexes bearing natural anti-inflammatory bioactives are also outlined. Characteristic examples of both free and metal-based porphyrins are explored. These compounds are recognized to have anti-inflammatory and antithrombotic assets, in addition to other pleiotropic advantages including antibacterial or anticancer actions. Additionally, applications of metal complexes in various models of inflammatory and thrombotic complications are demonstrated. The combined results of this study show that further research is required towards the preparation of several metal-based complexes with improved pharmacological profiles. Finally, restrictions on the application of these metal-based compounds are also covered, along with their prospects for the future and the need for additional study in order to improve their efficacy and safety.","PeriodicalId":10621,"journal":{"name":"Compounds","volume":"103 29","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141361394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Feature Papers in Compounds (2022–2023) 化合物专题论文（2022-2023 年）

Compounds Pub Date : 2024-06-06 DOI: 10.3390/compounds4020021

J. Mejuto

引用次数: 1

Alkaline Fading of Malachite Green in β-Cyclodextrins 孔雀石绿在β-环糊精中的碱性褪色

Compounds Pub Date : 2024-05-13 DOI: 10.3390/compounds4020019

Anton Soria-Lopez, Raquel Rodriguez-Fernández, Juan C. Mejuto

引用次数: 0

New Data on the Reactions of Zirconium and Hafnium Tetrachlorides with Aliphatic Acids 锆和铪四氯化物与脂肪族酸反应的新数据

Compounds Pub Date : 2024-05-08 DOI: 10.3390/compounds4020018

V. D. Makhaev, Larisa A. Petrova, Gennadii V. Shilov, Sergey M. Aldoshin

{"title":"New Data on the Reactions of Zirconium and Hafnium Tetrachlorides with Aliphatic Acids","authors":"V. D. Makhaev, Larisa A. Petrova, Gennadii V. Shilov, Sergey M. Aldoshin","doi":"10.3390/compounds4020018","DOIUrl":"https://doi.org/10.3390/compounds4020018","url":null,"abstract":"The reaction of ZrCl4 or HfCl4 with excess 2-methylpropanoic acid when boiling under reflux has been studied. The formation of polynuclear Zr and Hf complexes of the composition M2O(i-C3H7CO2)6 during prolonged reflux of the reaction mixtures was found. The complexes are very sensitive to hydrolysis, forming hexanuclear [M6(O)4(OH)4(i-C3H7CO2)12]. The reactions have a general character for aliphatic acids and can be used as an alternative to the known methods for the synthesis of polynuclear carboxylate clusters of Group 4 metals. The crystal and molecular structures of previously undescribed {[Hf6(μ3-O)4(μ3-OH)4(i-C3H7CO2)12(H2O)]·3i-C3H7COOH} have been determined. The molecular structure is a completely asymmetric hexanuclear cluster containing six Hf(IV) atoms united by a 4:4 μ3-O/OH system of bridges, and stabilized by twelve 2-methylpropanoate ligands, eight of which are bidentate bridging, three are chelating, and one is monodentate. The crystal structure of the complex includes three independent solvating 2-methylpropanoic acid molecules. The obtained IR spectroscopy data make it possible to determine the type of complexes in the reaction mixture. The results of the study may be useful for improving the catalytic systems for ethylene oligomerization.","PeriodicalId":10621,"journal":{"name":"Compounds","volume":" 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140998817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ultrasonication-Assisted Aqueous Extraction of Waste Orange Peel Polyphenols: Optimization of Process Variables and Effect on Extract Composition 超声波辅助水萃取废橘皮多酚：工艺变量的优化及其对提取物成分的影响

Compounds Pub Date : 2024-04-18 DOI: 10.3390/compounds4020016

Katiana Belsi, Xenia Vogiatzi, D. Palaiogiannis, Theodoros G. Chatzimitakos, S. Lalas, D. Makris

{"title":"Ultrasonication-Assisted Aqueous Extraction of Waste Orange Peel Polyphenols: Optimization of Process Variables and Effect on Extract Composition","authors":"Katiana Belsi, Xenia Vogiatzi, D. Palaiogiannis, Theodoros G. Chatzimitakos, S. Lalas, D. Makris","doi":"10.3390/compounds4020016","DOIUrl":"https://doi.org/10.3390/compounds4020016","url":null,"abstract":"The citrus processing industry is responsible for the generation of large volumes of waste side streams, represented principally by fruit peels. These tissues are exceptionally rich in polyphenolic bioactive phytochemicals, and there has been a great industrial interest for their valorization. The examination presented herein targeted at developing a fast and straight-forward aqueous extraction process, based on ultrasonication, for the efficacious recovery of polyphenolic compounds from waste orange peels. After an initial single-factor examination, the response surface optimization showed that a maximum total polyphenol yield of 12.81 mg chlorogenic acid equivalents (GAE) per g−1 dry mass could be achieved by setting sonicator amplitude at 80%, for 15 min, using a duty cycle of 2/2 (2 s on/2 s off). Comparison of this methodology with a stirred-tank extraction demonstrated that the ultrasonication technique was equally effective, requiring ambient temperature and considerably shorter resident time. The combination of both techniques using the ultrasonication process as a pretreatment step did not boost extraction yield, and the extracts produced had similar polyphenolic composition and antioxidant activity. However, a slight enhancement of the recovery of individual constituents was noted. It is proposed that efficient extraction of polyphenolic substances from waste orange peels may be accomplished using the present methodology, which is a low-cost (ambient temperature, short time) and sustainable (water as solvent) process.","PeriodicalId":10621,"journal":{"name":"Compounds","volume":" 45","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140687186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

(1E)-1,2-Diaryldiazene Derivatives Containing a Donor–π-Acceptor-Type Tolane Skeleton as Smectic Liquid–Crystalline Dyes (1E)-1,2-二芳基二氮烯衍生物，含有作为胶凝液晶染料的供体-π-受体型甲苯骨架

Compounds Pub Date : 2024-04-17 DOI: 10.3390/compounds4020015

S. Yamada, Keigo Yoshida, Yuto Eguchi, Mitsuo Hara, M. Yasui, Tsutomu Konno

{"title":"(1E)-1,2-Diaryldiazene Derivatives Containing a Donor–π-Acceptor-Type Tolane Skeleton as Smectic Liquid–Crystalline Dyes","authors":"S. Yamada, Keigo Yoshida, Yuto Eguchi, Mitsuo Hara, M. Yasui, Tsutomu Konno","doi":"10.3390/compounds4020015","DOIUrl":"https://doi.org/10.3390/compounds4020015","url":null,"abstract":"Considerable attention has been paid to (1E)-1,2-diaryldiazenes (azo dyes) possessing liquid–crystalline (LC) and optical properties because they can switch color through thermal phase transitions and photoisomerizations. Although multifunctional molecules with both LC and fluorescent properties based on a donor–π-acceptor (D-π-A)-type tolane skeleton have been developed, functional molecules possessing LC and dye properties have not yet been developed. Therefore, this study proposes to develop LC dyes consisting of (1E)-1,2-diaryldiazenes with a D–π-A-type tolane skeleton as the aryl moiety. The (1E)-1,2-diaryldiazene derivatives exhibited a smectic phase, regardless of the flexible-chain structure, whereas the melting temperature was significantly increased by introducing fluoroalkyl moieties into the flexible chain. Evaluation of the optical properties revealed that compounds with decyloxy chains exhibited an orange color, whereas compounds with semifluoroalkoxy chains absorbed at a slightly blue-shifted wavelength, which resulted in a pale orange color. The thermal phase transition caused a slight color change accompanied by a change in the absorption properties, photoisomerization-induced shrinkage, and partial disappearance of the LC domain. These results indicate that (1E)-1,2-diaryldiazenes with a D–π-A-type tolane skeleton can function as thermo- or photoresponsive dyes and are applicable to smart windows and in photolithography.","PeriodicalId":10621,"journal":{"name":"Compounds","volume":"5 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140693154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

NOx Storage and Reduction (NSR) Performance of Sr-Doped LaCoO3 Perovskite Prepared by Glycine-Assisted Solution Combustion 甘氨酸辅助溶液燃烧法制备的掺锶 LaCoO3 包晶石的氮氧化物储存和还原 (NSR) 性能

Compounds Pub Date : 2024-04-08 DOI: 10.3390/compounds4020014

Xinru Luan, Xudong Wang, Tianfei Zhang, Liangran Gan, Jianxun Liu, Yujia Zhai, Wei Liu, Liguo Wang, Zhongpeng Wang

{"title":"NOx Storage and Reduction (NSR) Performance of Sr-Doped LaCoO3 Perovskite Prepared by Glycine-Assisted Solution Combustion","authors":"Xinru Luan, Xudong Wang, Tianfei Zhang, Liangran Gan, Jianxun Liu, Yujia Zhai, Wei Liu, Liguo Wang, Zhongpeng Wang","doi":"10.3390/compounds4020014","DOIUrl":"https://doi.org/10.3390/compounds4020014","url":null,"abstract":"Here, we successfully synthesized Sr-doped perovskite-type oxides of La1−xSrxCo1−λO3−δ, “LSX” (x = 0, 0.1, 0.3, 0.5, 0.7), using the glycine-assisted solution combustion method. The effect of strontium doping on the catalyst structure, NO to NO2 conversion, NOx adsorption and storage, and NOx reduction performance were investigated. The physicochemical properties of the catalysts were studied by XRD, SEM-EDS, N2 adsorption–desorption, FTIR, H2-TPR, O2-TPD, and XPS techniques. The NSR performance of LaCoO3 perovskite was improved after Sr doping. Specifically, the perovskite with 50% of Sr doping (LS5 sample) exhibited excellent NOx storage capacity within a wide temperature range (200–400 °C), and excellent stability after hydrothermal and sulfur poisoning. It also displayed the highest NOx adsorption–storage capacity (NAC: 1889 μmol/g; NSC: 1048 μmol/g) at 300 °C. This superior performance of the LS5 catalyst can be attributed to its superior reducibility, better NO oxidation capacity, increased surface Co2+ concentration, and, in particular, its generation of more oxygen vacancies. FTIR results further revealed that the LSX catalysts primarily store NOx through the “nitrate route”. During the lean–rich cycle tests, we observed an average NOx conversion rate of over 50% in the temperature range of 200–300 °C, with a maximum conversion rate of 61% achieved at 250 °C.","PeriodicalId":10621,"journal":{"name":"Compounds","volume":"40 22","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140728152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Compounds最新文献