Complementary therapies in medicine最新文献

{"title":"Acupuncture for poststroke coma: A systematic review and meta-analysis","authors":"Yulun Wu ,&nbsp;Kun Zhao ,&nbsp;Wanshun Wen,&nbsp;Keying Zhu,&nbsp;Fei’ao Lu,&nbsp;Yurou Kong,&nbsp;Xiangming Ye ,&nbsp;Hui Wang","doi":"10.1016/j.ctim.2024.103046","DOIUrl":"10.1016/j.ctim.2024.103046","url":null,"abstract":"<div><h3>Background</h3><p>Despite being widely applied in clinical practice, the wake-promoting effect of acupuncture in poststroke coma patients remains controversial.</p></div><div><h3>Objective</h3><p>This study aimed to evaluate the efficacy of acupuncture for the treatment of poststroke coma.</p></div><div><h3>Methods</h3><p>Randomized controlled trials (RCTs) of acupuncture for treating poststroke coma were identified in PubMed, Cochrane Library, EMBASE, CNKI, WanFang and VIP up to 25 November 2023. The main outcomes were Glasgow Coma Scale (GCS) score, National Institute of Health Stroke Scale (NIHSS) score, awakening ratio and clinically effective ratio. Stata 17 and Review Manager 5.4 software were used for mate analysis.</p></div><div><h3>Results</h3><p>A total of 34 RCTs involving 2757 patients were included. GCS (WMD = 1.78; 95% CI: 1.35 to 2.21) and NIHSS score (WMD = −2.84; 95% CI: −3.84 to −1.84) were significantly increased in acupuncture group compared with control group. Acupuncture combined with routine treatment may be better than routine treatment in improving the awakening ratio (RR= 1.65; 95% CI: 1.24 to 2.91) and the clinically effective ratio (RR= 1.20; 95% CI: 1.13 to 1.27). Some methodological flaws were identified in the included studies, including non-implementation of blinding, inappropriate disease assessment and heterogeneous interventions.</p></div><div><h3>Conclusions</h3><p>The existing evidence suggests that acupuncture combined with conventional treatment may be an effective treatment for poststroke coma patients. In the meantime, more high-quality RCTs are needed to demonstrate these findings due to methodological weaknesses like randomization, blinding, heterogeneous interventions and long-term follow-up.</p></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0965229924000347/pdfft?md5=44f265121226eb129fb07426aa08480f&pid=1-s2.0-S0965229924000347-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140854580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Equine-assisted service’s effect on cartilage and skeletal biomarkers for adults and older adults with arthritis: A pilot study","authors":"Matthew Chrisman,&nbsp;Sharon White-Lewis,&nbsp;Sue Lasiter,&nbsp;Steven R. Chesnut,&nbsp;Cynthia L. Russell","doi":"10.1016/j.ctim.2024.103047","DOIUrl":"https://doi.org/10.1016/j.ctim.2024.103047","url":null,"abstract":"<div><h3>Objective</h3><p>The object of this study was to determine the effect of EAS (Equine-Assisted Services) on arthritis conditions, as measured by the sTnT (Skeletal troponin) and COMP (cartilage oligomeric matrix proteins) biomarkers, compared to an exercise attention control intervention.</p></div><div><h3>Design</h3><p>This was a secondary analysis of a randomized clinical trial comparing equine-assisted therapy to exercise education attention-control on cartilage and skeletal biomarkers in adults with arthritis. Twenty-one adults (<em>M</em>_age = 64 years) with arthritis who attended rheumatology clinics in the midwestern United States participated.</p></div><div><h3>Results</h3><p>No changes were found in sTnT from baseline to week six within either intervention nor were there differences in changes between the two groups (<em>p</em> = 0.91). COMP increased from baseline to week six for both conditions, suggesting increased deterioration of cartilage and joints. Although the attention-control condition demonstrated larger increases in cartilage oligomeric matrix proteins level, compared to the EAS condition, these differences were not statistically (<em>p</em> = 0.58) or clinically significant (i.e., trivial effect, <em>d</em> = −0.16). When 3 outliers were removed, the differences in changes between EAT and attention-control group could be arguably of clinical significance (<em>d</em> = - 0.33), suggesting that the attention-control group demonstrated larger increases in levels of COMP than those in the EAS condition, though this difference was not statistically significant (<em>p</em> = 0.28).</p></div><div><h3>Conclusion</h3><p>Although equine-assisted therapy may reduce pain and improve quality of life for adults with arthritis, findings here are not fully corroborated with biomarkers.</p></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0965229924000359/pdfft?md5=778aa152581db1f057eb61f5ac7bc57b&pid=1-s2.0-S0965229924000359-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140822695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reported biological effects following Osteopathic Manipulative Treatment: A comprehensive mapping review","authors":"Fulvio Dal Farra ,&nbsp;Andrea Bergna ,&nbsp;Christian Lunghi ,&nbsp;Irene Bruini ,&nbsp;Matteo Galli ,&nbsp;Luca Vismara ,&nbsp;Marco Tramontano","doi":"10.1016/j.ctim.2024.103043","DOIUrl":"https://doi.org/10.1016/j.ctim.2024.103043","url":null,"abstract":"<div><h3>Background and purpose</h3><p>Osteopathic Manipulative Treatment (OMT) is a therapeutic whole-body approach mainly focused on correcting somatic dysfunctions. The aim of this scoping review is to systematically map the literature regarding the documented biological effects observed following OMT.</p></div><div><h3>Methods</h3><p>The 2020 JBIRM version and the PRISMA-ScR were followed for the conceptualization and reporting of this review. The protocol was registered on the “Open Science Framework Registry” (<span>https://doi.org/10.17605/OSF.IO/MFAUP</span><svg><path></path></svg>). We searched for original articles published on Medline, Embase, and Scopus, from inception to the present.</p></div><div><h3>Results</h3><p>Overall, 10,419 records were identified. After duplicate removal, screening for title and abstract, and specific exclusions with reasons, a total of 146 studies were included. Wide differences were detected among studies in their geographical localization, study design, temporal distribution, participants’ condition, OMT protocols, and documented biological effects. Such variety in frequency distribution was properly described through descriptive statistics.</p></div><div><h3>Conclusions</h3><p>Biological modifications that appear to be induced by OMT have been detected in several body systems, but mostly in neurophysiological correlates and musculoskeletal changes. Results suggest a growing interest over the years on this topic, especially in the last two decades. More efforts in research are recommended to highlight whether such changes specifically depend on OMT, and to demonstrate its specific contribution to clinical practice.</p></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0965229924000311/pdfft?md5=90b7d77d58dcdd170f364f0b55c9f21b&pid=1-s2.0-S0965229924000311-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140816922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of acupuncture as adjunct therapy for sleep disorders in Parkinson's disease: A systematic review and meta-analysis","authors":"Wenjing Mi ,&nbsp;Miaomiao Meng ,&nbsp;Fenghua Xu ,&nbsp;Lingzhi Sun","doi":"10.1016/j.ctim.2024.103044","DOIUrl":"https://doi.org/10.1016/j.ctim.2024.103044","url":null,"abstract":"<div><h3>Objective</h3><p>The purpose of this study was to summarize existing clinical studies through a systematic review to explore the efficacy of acupuncture in treating sleep disorders in PD patients.</p></div><div><h3>Methods</h3><p>According to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, we retrieved the papers through 30 April 2023 from eight databases. The experimental group was treated with acupuncture plus conventional therapy, while the control group was treated with conventional therapy alone or combined with sham acupuncture. The sleep quality was the primary outcome. A team of researchers meticulously performed literature screening, data extraction and risk of bias assessment following the Cochrane Handbook. A meta-analysis was synthesized using Review Manager Version 5.4 software if feasible. The quality of the evidence was assessed by the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) tool.</p></div><div><h3>Results</h3><p>A total of 973 papers were identified, with 15 papers involving 957 patients were included in this systematic review. The results showed that acupuncture interventions included manual acupuncture, electroacupuncture, moxibustion and bleeding, with 1–7 times every week implemented during 2–12 weeks. Acupuncture as an adjunct therapy compared to conventional therapy alone showed better effect in sleep quality and overall symptoms of PD. Risk of bias assessment showed deficiencies in blinding and allocation concealment. All included studies were synthesized in a meta-analysis, as the result of which, acupuncture improved PDSS scores(MD =16.57; 95% CI, 7.24–25.90; <em>I</em>^<em>2</em> = 97%) and effective rate for sleep disorders (OR = 5.91; 95% CI, 1.71–20.39; <em>I</em>^<em>2</em> = 54%); meanwhile, acupuncture reduced UPDRS scores(MD = −4.29; 95% CI, −6.54 – −2.03; <em>I</em>^<em>2</em> = 77%) and improved effective rate for PD (OR = 3.22; 95% CI, 1.81–5.72; <em>I</em>^<em>2</em> = 0%). The quality of evidence ranged from low to moderate by GRADE.</p></div><div><h3>Conclusion</h3><p>This study provides initial evidence that acupuncture as an adjunct therapy might be associated with improvement of sleep disorders in PD. Due to the lack of high-quality studies, larger sample size studies with sham acupuncture groups should be conducted in future.</p></div><div><h3>Registration number</h3><p>CRD42022364249 (PROSPERO).</p></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0965229924000323/pdfft?md5=07409d000cacae30259e4825a53a6f8f&pid=1-s2.0-S0965229924000323-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140816894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effects of jujube (Ziziphus jujube) on metabolic and mental health outcomes in patients with metabolic syndrome: A randomized controlled trial","authors":"Karim Parastouei ,&nbsp;Saad Badai Nashtar ,&nbsp;Zaid Al-Attar ,&nbsp;Parivash Shekarchizadeh-Esfahani ,&nbsp;Gholamreza Askari","doi":"10.1016/j.ctim.2024.103041","DOIUrl":"10.1016/j.ctim.2024.103041","url":null,"abstract":"<div><h3>Objectives</h3><p>The effects of jujube (<em>Ziziphus jujube</em>) consumption on metabolic and mental health outcomes in subjects diagnosed with metabolic syndrome (MetS) is unknown and remains to be examined. Hence, we carried out a parallel-group, randomized controlled trial to investigate this issue.</p></div><div><h3>Methods</h3><p>Eligible participants were randomly assigned to the intervention (n = 30) or the control (n = 30) groups to receive either jujube or a placebo for eight weeks. Subjects were provided with 30 g dried jujube powder or placebo and were asked to consume half of the powder at 10 a.m. and the rest at 4 p.m. Lipid profile, fasting blood glucose (FBG), waist circumference (WC), and blood pressure were evaluated as primary outcomes. Secondary outcomes collected were mental health measures (e.g., depression, anxiety, and stress).</p></div><div><h3>Results</h3><p>Jujube consumption failed to decrease FBG, total cholesterol, low-density lipoprotein cholesterol, and blood pressure, as well as depression and anxiety scores (P &gt; 0.05). However, the between-group comparison revealed a significant improvement in WC (− 3.98 vs. − 0.51, P = 0.01), triglyceride (TG) (− 24.96 vs. − 0.73, P = 0.03), and high-density lipoprotein cholesterol (HDL-C) (2.83 vs. 0.40, P = 0.01) in the jujube group compared to the placebo. In addition, compared to the control group, jujube consumption led to a significant improvement in the score of stress (− 5.80 vs. − 2.86, P = 0.01).</p></div><div><h3>Conclusion</h3><p>Jujube consumption only had beneficial effects on WC, TG, and HDL-C in subjects with MetS. However, the current study has methodological weaknesses in blinding and herb purity/potency testing, which should be addressed in future studies.</p></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0965229924000293/pdfft?md5=f45086623ee28276fa02029834bd853e&pid=1-s2.0-S0965229924000293-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140758005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of a guideline for supportive anthroposophic therapies for hospitalised children with acute gastroenteritis – A prospective case series study","authors":"Melanie Schwermer ,&nbsp;Katharina Fetz ,&nbsp;Thomas Ostermann ,&nbsp;Louisa Truxius ,&nbsp;Alfred Längler ,&nbsp;Tycho Jan Zuzak","doi":"10.1016/j.ctim.2024.103042","DOIUrl":"https://doi.org/10.1016/j.ctim.2024.103042","url":null,"abstract":"<div><h3>Objective</h3><p>Even though several German children’s hospitals offer integrative, anthroposophic medical therapies in addition to the standard medical care, guidelines for these anthroposophic therapies are still rare. Therefore, we investigated the feasibility of implementing a published, consensus-based guideline for the treatment of children with acute gastroenteritis (aGE) with anthroposophic therapies in the community hospital Herdecke.</p></div><div><h3>Design</h3><p>A prospective case series of paediatric patients (≤18 years) with an aGE admitted to the department of integrative paediatrics of the community hospital Herdecke was conducted. Demographic, clinical and therapeutic data was recorded at initial presentation and at follow-up visits. Physicians were surveyed with a questionnaire to evaluate feasibility of implementing the guideline.</p></div><div><h3>Results</h3><p>Sixty-two patients (0–15 years; 22 male, 40 female) were included in the case series. All patients received some form of anthroposophic therapy. The most frequently used remedies were Geum urbanum, Nux vomica and Bolus alba comp. Treating physicians showed a high adherence to the expert-based consensus guideline in their prescribed therapies. All physicians stated that they were familiar with the guideline and used the recommendation to inform their therapy decision. Suitability for daily use and effectiveness in treating the main symptoms of aGE were highly scored by the physicians.</p></div><div><h3>Conclusion</h3><p>The consensus-based guideline of anthroposophic therapies for aGE in children was successfully implemented and found to be useful for physicians in clinical practice.</p></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S096522992400030X/pdfft?md5=c36d680cdeb44563557d7a5aa95287fd&pid=1-s2.0-S096522992400030X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140619012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Traditional chinese medicine injections with activating blood circulation, equivalent effect of anticoagulation or antiplatelet, for acute myocardial infarction: A systematic review and meta-analysis of randomized clinical trials","authors":"Xueyan Sun,&nbsp;Jiaping Chen,&nbsp;Juju Shang,&nbsp;Hongxu Liu,&nbsp;Xiang Li,&nbsp;Yan Lou,&nbsp;Huiwen Zhou","doi":"10.1016/j.ctim.2024.103039","DOIUrl":"https://doi.org/10.1016/j.ctim.2024.103039","url":null,"abstract":"<div><h3>Background</h3><p>Traditional Chinese medicine injection for Activating Blood Circulation (TCMi-ABC), which exhibits comparable anticoagulant and antiplatelet effects, is commonly used as an adjuvant treatment for acute myocardial infarction (AMI) in China.</p></div><div><h3>Objective</h3><p>The aim of this study was to conduct a meta-analysis to assess the efficacy and safety of TCMi-ABC in combination with conventional western medicine in reducing mortality associated with AMI.</p></div><div><h3>Methods</h3><p>We conducted a comprehensive search of PubMed, Cochrane Library, EMBASE, Web of Science, CBM, WanFang Data, and CNKI databases. Randomized controlled trials (RCTs) investigating the use of TCMi-ABC (including Danhong injection, sodium tanshinone IIA sulfonate injection, salvia miltiorrhiza ligupyrazine injection, and puerarin injection) for the treatment of AMI were included. The search included studies published from the inception of the databases up to December 2022. Two authors independently screened RCTs, extracted data, and assessed the risk of bias. Meta-analysis was performed using RevMan 5.3 and Stata 17.0. The quality of evidence was evaluated using the GRADE approach.</p></div><div><h3>Results</h3><p>A total of 52 RCTs involving 5363 patients were included in the analysis, none of which described independent testing of the purity or potency of the TCMi-ABC product used. 19/52 reported random sequence generation. All RCTs lack adequate description of allocation concealment. 51/52 failed to assess blinding. The meta-analysis results demonstrated that the combined application of TCMi-ABC, compared with conventional western medicine treatment alone, significantly reduced in-hospital mortality in AMI patients [RR= 0.41, 95% CI (0.29, 0.59), P &lt; 0.05], decreased the incidence of malignant arrhythmia [RR= 0.40, 95% CI (0.26, 0.61), P &lt; 0.05], and increased left ventricular ejection fraction (LVEF) [MD= 5.53, 95% CI (3.81, 7.26), P &lt; 0.05]. There was no significant difference in the incidence of adverse events between the two groups (P &gt; 0.05). The GRADE evidence quality classification indicated that the evidence for in-hospital mortality, malignant arrhythmia, and adverse events was of moderate quality, while the evidence for LVEF was of low quality.</p></div><div><h3>Conclusion</h3><p>TCMi-ABC demonstrates additional clinical value in reducing mortality and the risk of malignant arrhythmia in patients with AMI. However, further validation of these findings is warranted through high-quality clinical trials due to methodological weaknesses in randomization, blinding, allocation concealment, and insufficient assessing for the purity/potency of herbs and the gram amount of active constituents.</p><p><strong>Systematic Review Registration:</strong> [INPLASY], identifier [INPLASY202170082]</p></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S096522992400027X/pdfft?md5=bb11a5e5dd2964cd85a75e8b2df719e5&pid=1-s2.0-S096522992400027X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140604838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bibliometric analysis of auriculotherapy research trends over the past 20 years","authors":"Hyonjun Chun ,&nbsp;Woo-Chul Shin ,&nbsp;Sungjun Joo ,&nbsp;Hyungsuk Kim ,&nbsp;Jae-Heung Cho ,&nbsp;Mi-Yeon Song ,&nbsp;Won-Seok Chung","doi":"10.1016/j.ctim.2024.103036","DOIUrl":"https://doi.org/10.1016/j.ctim.2024.103036","url":null,"abstract":"<div><h3>Objectives</h3><p>Auriculotherapy has long been used to treat various diseases. We analyzed and visualized auriculotherapy’s geographical distribution, key contributors, and thematic trends over the past 20 years to provide current trends in auriculotherapy field and to offer recommendations for future research directions.</p></div><div><h3>Design/setting</h3><p>We searched for relevant studies in the Web of Science between January 10, 2003, and December 31, 2022. A bibliometric analysis was performed using VOSviewer for annual publications, journals, countries, institutions, authors, and keywords.</p></div><div><h3>Results</h3><p>A total of 800 studies were included in the analysis, and the number of studies steadily increased over the 20 examined years. In 2018, there was a noteworthy rise in publications, nearly twice as many as the preceding year. Integrative &amp; complementary medicine was the most researched area, with most articles published in <em>Evidence-Based Complementary and Alternative Medicine</em>. China was the country with the most published research, and the most active organization was Guangzhou University of Chinese Medicine in China, followed by Kyung Hee University in South Korea. The most prolific author was Yeh Mei-ling, who reported the effects of auriculotherapy on dysmenorrhea and smoking cessation. Keyword analysis revealed four clusters: pain, mental health, obesity, and smoking cessation.</p></div><div><h3>Conclusion</h3><p>Auriculotherapy research primarily focused on clinical studies related to pain, obesity, smoking cessation, and depression. Future research should place greater emphasis on verifying the mechanisms of auriculotherapy for specific ailments and may require efforts to enhance the robustness of clinical trials. Through visual analysis, our study may serve as a foundational resource, offering valuable insights into the trajectory of auriculotherapy research.</p></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0965229924000244/pdfft?md5=770b03a57cf976a399bc0f0ac024afa6&pid=1-s2.0-S0965229924000244-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140558231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inflammation and physical activity in multiple sclerosis patients. A systematic review and meta-analysis","authors":"V. Bellisario ,&nbsp;G. Squillacioti ,&nbsp;F. Ghelli ,&nbsp;MC. Monti ,&nbsp;L. Correale ,&nbsp;C. Montomoli ,&nbsp;R. Bono","doi":"10.1016/j.ctim.2024.103040","DOIUrl":"https://doi.org/10.1016/j.ctim.2024.103040","url":null,"abstract":"<div><h3>Objectives</h3><p>Due to the inflammatory nature of multiple sclerosis (MS), the most widely used therapeutic approach targets the immune response but can comprise side effects (e.g. secondary immunosuppression). For these reasons, among non-pharmaceutical interventions without known side effects, physical activity (PA) gained importance because it is feasible, safe and a supportive complementary treatment strategy to alleviate symptoms in MS subjects. Consequently, the main aim of this systematic review is to analyze the effect of PA protocols, as a complementary therapy, on inflammatory status in MS patients.</p></div><div><h3>Methods</h3><p>Four electronic databases (PubMed, Embase, CINAHL, and Cochrane CENTRAL) were systematically searched up to 01 June 2023 (Prospero Protocol ID=CRD42021244418). The refined search strategy was based on three concepts: “MULTIPLE SCLEROSIS” AND “PHYSICAL ACTIVITY” AND “INFLAMMATION”.</p></div><div><h3>Results</h3><p>three main findings emerged: 1) untrained subjects showed a negative modulation of inflammatory biomarkers concentrations when compared to trained people (−0.74, 95 %C.I.–1.16, −0.32); 2) training modulated positively inflammatory biomarkers (+0.47, 95 %C.I. 0.24,0.71); 3) Aerobic PA protocol enhance higher positive influence on inflammation.</p></div><div><h3>Conclusions</h3><p>Persistent, low-grade inflammation in MS could be upregulated by non-pharmacological complementary therapies, in particular by regular aerobic PA that could reduce and positively modulate inflammation.</p></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0965229924000281/pdfft?md5=05eacc8e6ea962fc12bbb28f9181a4fe&pid=1-s2.0-S0965229924000281-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140550848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A bibliometric study on trends in chiropractic research from 1920 to 2023","authors":"Yi-ping Song ,&nbsp;Jia-li Liu ,&nbsp;Chen-zhong Zong ,&nbsp;Fang-shuo Zhang ,&nbsp;Yan-feng Ren ,&nbsp;Yuen-Lim Ching ,&nbsp;Yi-xiao Wang ,&nbsp;Wen-xun Li ,&nbsp;He Zhao ,&nbsp;Yi-ran Huang ,&nbsp;Kuo Gao","doi":"10.1016/j.ctim.2024.103038","DOIUrl":"https://doi.org/10.1016/j.ctim.2024.103038","url":null,"abstract":"<div><h3>Objective</h3><p>An increasing body of evidence suggests a positive role of chiropractic in the treatment of neuro-musculoskeletal disorders. This study aims to explore current research hotspots and trends, providing insights into the broad prospects of this field.</p></div><div><h3>Methods</h3><p>A bibliometric review was conducted on all chiropractic articles included in the Web of Science Core Collection before December 31, 2023.</p></div><div><h3>Results</h3><p>Over the past century, the volume of research in the field of chiropractic has been fluctuating annually, with four peaks observed in total. The United States, Canada, Australia, and the United Kingdom are leading countries. Chu, Eric Chun-Pu is the author with the most publications, while Bronfort, Gert has the highest total citation count. The University of Southern Denmark has produced the most publications, while Queens University - Canada is the most central institution. The Journal of Manipulative and Physiological Therapeutics is the journal with the most publications and citations, while the Journal of the American Medical Association is the most central journal. The two most-cited articles were both authored by Eisenberg DM. Emerging keywords include \"chronic pain\" and \"skills\". The theoretical mechanisms and scientific basis of chiropractic, its clinical practice and safety, education and training, integration with other disciplines, and patient experiences and satisfaction are the frontiers and hotspots of research.</p></div><div><h3>Conclusion</h3><p>This study integrates bibliometric analysis to summarize the current state of research and global network centers in the field of chiropractic, further highlighting the hotspots and trends in this field. However, Individual and national rankings should be interpreted with caution due to our focus on Web of Science rather than PubMed.</p></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0965229924000268/pdfft?md5=dc0e044272d22621e0d3ee622650dd90&pid=1-s2.0-S0965229924000268-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140533707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}