Complementary therapies in medicine最新文献

{"title":"Understanding and enhancing post-stroke recovery: Insights from a nested qualitative study within the MindFit Project randomized clinical trial","authors":"Adrià Bermudo-Gallaguet ,&nbsp;Jofre Bielsa-Pascual ,&nbsp;Rosa García-Sierra ,&nbsp;Maria Feijoo-Cid ,&nbsp;Antonia Arreciado Marañon ,&nbsp;Mar Ariza ,&nbsp;Daniela Agudelo ,&nbsp;Neus Camins-Vila ,&nbsp;Maria Boldó ,&nbsp;Maria José Durà Mata ,&nbsp;Alberto García-Molina ,&nbsp;Pere Torán-Monserrat ,&nbsp;Maria Mataró","doi":"10.1016/j.ctim.2024.103100","DOIUrl":"10.1016/j.ctim.2024.103100","url":null,"abstract":"<div><h3>Background</h3><div>Stroke survivors experience a wide range of physical, cognitive, and emotional challenges. In the MindFit Project, a randomized clinical trial, 141 chronic stroke patients were divided into three groups: mindfulness-based stress reduction (MBSR) with computerized cognitive training (CCT), physical exercise (PE) with CCT, and CCT alone. The interventions were conducted remotely over 12 weeks, including online group and individual sessions.</div></div><div><h3>Objective</h3><div>This exploratory nested qualitative study aimed to investigate chronic stroke survivors’ experiences, opinions, and perceived changes due to the interventions within the MindFit Project. The secondary objective was to describe the broader experience of their recovery journey.</div></div><div><h3>Methods</h3><div>Twenty-seven participants were recruited through purposive sampling and engaged in semi-structured one-on-one interviews. Twelve received MBSR+CCT, nine received PE+CCT, and six received CCT-only. The interviews were recorded, transcribed, and analyzed using thematic analysis.</div></div><div><h3>Results</h3><div>Participants shared insights into their lives after stroke, including emotional and physical challenges, coping mechanisms, and the impact of societal perceptions. The interventions were generally positively valued, with MBSR aiding in emotional regulation, PE enhancing physical capabilities, and CCT improving cognition. The group setting provided valuable peer support and motivation, although some participants noted challenges owing to the heterogeneity. The telematic format was also appreciated for its accessibility, although it posed challenges to personal interaction and intervention supervision.</div></div><div><h3>Conclusions</h3><div>Our study emphasizes the complexity of stroke recovery and the importance of holistic, patient-centered rehabilitation approaches. It also highlights the value of combining physical and non-physical interventions in a group setting, along with the potential of remote platforms to enhance the accessibility of rehabilitation programs. These findings generate hypotheses for future randomized clinical trials aimed at improving post-stroke recovery.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"87 ","pages":"Article 103100"},"PeriodicalIF":3.3,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142459780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tuina versus physiotherapy or a combination of both for the management of chronic nonspecific low back pain: A randomized controlled trial","authors":"Qingyu Ma ,&nbsp;Xuan Zhou ,&nbsp;Huifang Liang ,&nbsp;Yu Guo ,&nbsp;Kejie He ,&nbsp;Longbin Shen ,&nbsp;Qiao Fan ,&nbsp;Juan Yang ,&nbsp;Tan Ia Choo Celia ,&nbsp;Brent A. Bauer ,&nbsp;Jiaxu Chen","doi":"10.1016/j.ctim.2024.103098","DOIUrl":"10.1016/j.ctim.2024.103098","url":null,"abstract":"<div><h3>Objective</h3><div>To rigorously evaluate the short-term and long-term effectiveness of <em>Tuina</em> (TN), alone and in combination with physiotherapy (PT), for Chronic nonspecific low back pain (CNLBP) through a comprehensive, high-quality clinical trial.</div></div><div><h3>Methods</h3><div>This randomized, single-blind trial was conducted from September 2020 to July 2023, involving 204 CNLBP patients from the First Affiliated Hospital of Jinan University. Participants underwent a baseline assessment, 6 treatment sessions over 8 weeks, a post-treatment evaluation in the 9th week, and a 20-week follow-up. Participants were randomly assigned to TN, PT, or a combination of TN and PT (TP) groups. Each treatment involved 6 sessions with a minimum 7-day interval, each lasting 30 minutes. Primary outcome was the change in Visual Analog Scale (VAS) for pain. Secondary outcomes included the Oswestry Disability Index (ODI), 36-Item Short Form Health Survey (SF-36), Range of Motion (ROM) of the spine, Traditional Chinese Medicine Syndrome Scale (TCMSS), and adverse events (AE).</div></div><div><h3>Results</h3><div>Among the 204 participants, 67.16 % were female, and 88.73 % completed the 20-week follow-up. All groups showed significant reductions in VAS scores post-treatment and at follow-up. Secondary outcomes improved significantly, with notable decreases in ODI and TCMSS scores. Pairwise comparisons within groups indicated statistical significance, particularly in ODI scores, with clinical relevance. No significant differences were found between the groups. ROM and SF-36 showed statistical but not clinical significance. Only one AE (0.49 %) was reported, with no severe incidents.</div></div><div><h3>Conclusion</h3><div>All treatment groups, including TN, TP, and PT, demonstrated significant reductions in VAS scores for CNLBP patients, with effects lasting up to 20 weeks. While TN and TP showed substantial improvements in secondary outcomes, particularly in ODI scores, no significant differences were found between the groups. These findings suggest that all treatments can be effective for managing CNLBP, supporting clinical practitioners in selecting appropriate interventions for patients, especially for those unable to engage in active exercises, utilizing passive movements like TN to enhance health outcomes.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"86 ","pages":"Article 103098"},"PeriodicalIF":3.3,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142433872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A large-scale, international cross-sectional survey of published pediatrics authors: Perceptions of complementary, alternative, and integrative medicine","authors":"Jeremy Y. Ng ,&nbsp;Gursimran Deol ,&nbsp;Dennis Anheyer ,&nbsp;Holger Cramer","doi":"10.1016/j.ctim.2024.103097","DOIUrl":"10.1016/j.ctim.2024.103097","url":null,"abstract":"<div><h3>Background</h3><div>The use of complementary, alternative, and integrative medicine (CAIM) is commonly used among pediatric patients for various conditions. Pediatrics clinicians’ and researchers’ perceptions towards the incorporation of CAIM therapies have varied. This study aims to investigate the perceptions of both pediatrics researchers and clinicians regarding CAIM.</div></div><div><h3>Methods</h3><div>We conducted a large-scale, international cross-sectional online survey with published pediatrics authors who have published their work in pediatrics medical journals that are indexed in MEDLINE. In total, 34 494 researchers and clinicians were invited to complete the survey. The survey recorded respondents’ perceptions on various CAIM therapies. Descriptive statistics were generated from the quantitative survey results. A thematic analysis was conducted for responses to open ended questions.</div></div><div><h3>Results</h3><div>In total, 731 pediatrics clinicians and/or researchers responded to the survey, with about half of the respondents being faculty members/principal investigators (56.10 %) and/or clinicians (43.45 %) and from the Americas (46.56 %) or Europe (30.53 %). Over half of the respondents viewed mind-body therapies favourably (62.01 %) and the fewest respondents held favourable perceptions of biofield therapies (6.98 %). Respondents agreed or strongly agreed that there is value in conducting further research on CAIM therapies (85.52 %) and disagreed or strongly disagreed that they felt comfortable recommending most CAIM therapies to patients (64.83 %). A thematic analysis of our findings demonstrates that many pediatrics clinicians and/or researchers support further research on CAIM.</div></div><div><h3>Conclusion</h3><div>The findings from this study demonstrate that pediatrics clinicians and researchers have varying perceptions towards CAIM therapies. Respondents had the most positive perceptions of mind-body therapies and felt they did not have adequate training on CAIM. Further research is needed to establish more evidence-based educational resources on CAIM.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"87 ","pages":"Article 103097"},"PeriodicalIF":3.3,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142399635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A systematic review of Selenium as a complementary treatment in cancer patients","authors":"Felix Krannich ,&nbsp;Ralph Mücke ,&nbsp;Jens Büntzel ,&nbsp;Lutz Schomburg ,&nbsp;Oliver Micke ,&nbsp;Jutta Hübner ,&nbsp;Jennifer Dörfler","doi":"10.1016/j.ctim.2024.103095","DOIUrl":"10.1016/j.ctim.2024.103095","url":null,"abstract":"<div><h3>Background</h3><div>Selenium, a trace element with antioxidant properties, has been widely studied for its benefits in cancer treatment. This systematic review aims to critically evaluate existing evidence on the effectiveness of selenium as a complementary treatment in cancer patients.</div></div><div><h3>Method</h3><div>In May 2023, a systematic search was conducted searching five electronic databases (Embase, Cochrane, PsychInfo, CINAHL and Medline) to find studies concerning the use, effectiveness and potential harm of selenium substitution therapy on adult cancer patients undergoing cancer treatment. Including and excluding patient criteria were defined beforehand.</div></div><div><h3>Results</h3><div>From 4511 search results, 12 studies in 14 publications with 2483 patients were included in this systematic review. Types of cancer covered in the reviewed studies are non-Hodgkin lymphoma, head and neck cancer, thyroid cancer, acute myeloid or acute lymphocytic leukaemia, stage I non-small lung cancer, breast cancer, cervical and endometrial cancer, prostate cancer and non-invasive urothelial carcinoma. Common outcomes were PSA change, radiotherapy associated toxicities, overall survival (OS), recurrence free interval (RFI) and quality of life (QoL). Most studies showed some concerns in the risk of bias evaluation. The results were heterogeneous: Regarding radiotherapy toxicities, patients with sufficient levels of Se at baseline do not profit of Se supplementation, while those with a deficiency of Se at baseline have significantly reduced toxicities on some scales. Regardless blood levels of Se, no benefit was found for OS, Recurrence Free Interval, Progression Free Interval, Quality of life and PSA compared to control/placebo group.</div></div><div><h3>Conclusion</h3><div>Due to the very heterogeneous results and methodical limitations of the included studies, a clear statement regarding the effectiveness of Se supplementation is not possible, whereas cancer patients with a Se deficiency could profit from a Se supplementation during radio- or chemotherapy. Further studies should define Se deficiency as inclusion criterion and analyze levels of Se during time of intervention.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"86 ","pages":"Article 103095"},"PeriodicalIF":3.3,"publicationDate":"2024-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142388670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A bibliometric analysis and visualization of literature on the relationship between vitamin D and obesity over the last two decades","authors":"Jie Xiong,&nbsp;Xuemei Luo,&nbsp;Liqun Liu,&nbsp;Xiaoxiang Gong","doi":"10.1016/j.ctim.2024.103093","DOIUrl":"10.1016/j.ctim.2024.103093","url":null,"abstract":"<div><h3>Objective</h3><div>The purpose of this study was to employ bibliometric analysis to visualize hot spots and evolving trends in the studies on the relationship between vitamin D and obesity.</div></div><div><h3>Methods</h3><div>From the Web of Science Core Collection database, articles on vitamin D and obesity from 2001 to 2021 were retrieved. For the bibliometric visualization analysis, CiteSpace was employed. Some of the figures were created using GraphPad software.</div></div><div><h3>Results</h3><div>4454 pieces of articles and reviews were found, with an average citation of 30.68 times. There are many more published papers in the area of \"nutrition dietetics\" (1166, 26.179 %). The United States possesses the largest number of publications (1297, 29.12 %) and demonstrates definitive leadership in this field. The League of European Research Universities generates a higher percentage of publications (256, 5.748 %) than other institutions. Major studies are funded by the United States Department of Health and Human Services (531, 11.922 %) and the National Institutes of Health, USA (528, 11.855 %). The top five keywords with the highest co-occurrence frequency are “obesity” (1260), “vitamin d” (943), “insulin resistance” (651), “risk” (642), and “d deficiency” (636). The biggest keyword cluster was #0 \"adolescent\" among the 18 keyword clusters. The three latest keywords in the keyword burst were \"mineral density\"、\"d insufficiency\" and \"25 hydroxyvitamin d concentration\".</div></div><div><h3>Conclusion</h3><div>This bibliometric analysis shows an overview of the current status of the research on the association between vitamin D and obesity. The prevalence of vitamin D deficiency and the relationship between vitamin D and metabolic syndrome in obese individuals remains hot topics. We speculate that the effect of obesity on vitamin D levels and bone mineral density, and the influence of vitamin D insufficiency on various body systems in obese populations will be future trends.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"86 ","pages":"Article 103093"},"PeriodicalIF":3.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142371186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects and safety of the traditional Chinese exercise baduanjin on depression and anxiety in COVID-19 patients: A systematic review and meta-analysis","authors":"Yan Huang ,&nbsp;Xiao Xu ,&nbsp;Bishal Kumar Chaurasiya ,&nbsp;Prudence Bizimana ,&nbsp;Mei-Juan Qian ,&nbsp;Epipode Ntawuyamara","doi":"10.1016/j.ctim.2024.103094","DOIUrl":"10.1016/j.ctim.2024.103094","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Aim&lt;/h3&gt;&lt;div&gt;This systematic review and meta-analysis aimed to assess the safety and efficacy of Baduanjin, a traditional Chinese exercise (TCM), for reducing depression and anxiety in individuals suffering from coronavirus disease 2019 (COVID-19).&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;div&gt;Nineteen databases were searched from their inception through August 2024 to gather data for this study. The focus of this study was randomized controlled trials (RCTs) in which Baduanjin was administered for the treatment of COVID-19 patients with depression and anxiety. The study included various types of Baduanjin exercise, whether used alone or in conjunction with other treatment modalities, for the control group. The comparators included a waitlist control, usual care, health education and supportive counseling, psychosocial support therapy, pharmacotherapies, and other common exercises. The exclusion criteria for trials were trials comparing different treatment durations, different treatment frequencies, and different types of Baduanjin exercise. Moreover, other traditional Chinese medicine (TCM) therapeutic methods applied in either the intervention or control group were also excluded. Throughout the entire study, the selection process, data extraction and quantitative analysis were carried out in strict adherence to all relevant guidelines. The Cochrane criteria for risk of bias were used to assess the methodological quality of the trials. In our review, a meta-analysis was performed using the software STATA MP14.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;After conducting a meta-analysis, eight RCTs were found to have satisfied the inclusion criteria. The effects of Baduanjin exercise on self-rating anxiety scale (SAS) scores were investigated in five RCTs comprising a total of 228 patients. Analysis of the results revealed that the combination of Baduanjin exercises and conventional therapies led to a statistically significant reduction in SAS scores [MD=-3.21 (95 % CI= −3.64, −2.79), &lt;em&gt;P&lt;/em&gt;&lt; 0.001] compared to conventional therapies alone. Moreover, this systematic review explored the effect of Baduanjin exercise on self-rating depression scale (SDS) scores (three RCTs involving 83 participants), Hamilton Anxiety Rating Scale (HAM-A) scores (one RCT involving 103 participants), Patient Health Questionnaire (PHQ-9) scores (one RCT involving 70 participants) and Generalized Anxiety Disorder-7 (GAD-7) scores (one RCT involving 59 participants) for patients with COVID-19. The results showed that, in addition to conventional therapies, Baduanjin exercise had a more favorable impact on reducing the SDS score [mean difference (MD) =-2.86 (95 % CI=4.11, −1.61), &lt;em&gt;P&lt;/em&gt;=0.025], &lt;em&gt;P&lt;/em&gt;HQ-9 score [MD=-5.31, 95 % CI=-8.73, −1.89), &lt;em&gt;P&lt;/em&gt;=0.002] and HAM-A score [MD=-3.00, 95 % CI=-5.33, −0.67], &lt;em&gt;P&lt;/em&gt;=0.010] in patients with COVID-19 than did the use of conventional therapies alone. Furthermore, the combination of Baduanjin exercise and conven","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"86 ","pages":"Article 103094"},"PeriodicalIF":3.3,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142358799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Music therapy in hemodialysis patients: Systematic review and meta-analysis","authors":"Feng Lin ,&nbsp;Long Chen ,&nbsp;Yin Gao","doi":"10.1016/j.ctim.2024.103090","DOIUrl":"10.1016/j.ctim.2024.103090","url":null,"abstract":"<div><h3>Background</h3><div>Patients undergoing hemodialysis (HD) face significant challenges; however, non-pharmaceutical interventions hold potential for enhancing their quality of life. This paper evaluates the effects of music therapy on various mental and physiological outcomes in patients undergoing HD.</div></div><div><h3>Methods</h3><div>This systematic review and meta-analysis followed the PRISMA 2020 guidelines. A comprehensive database search conducted up to May 21, 2024, identified studies for inclusion based on PICOS criteria. The methodological quality of these studies was assessed using the Cochrane risk-of-bias tool and Review Manager 5.4. For the meta-analysis, R and Stata/SE 15.1 were used, applying a random-effects model in cases of significant heterogeneity, and a fixed-effects model when heterogeneity was minimal.</div></div><div><h3>Results</h3><div>Twenty-four studies involving 1703 participants were analyzed. Music therapy significantly decreased anxiety (SMD: −0.72, 95 % CI: −0.97 to −0.46, I²: 83 %), pain (SMD: −1.22, 95 % CI: −1.68 to −0.75, I²: 93 %), depression (SMD: −0.85, 95 % CI: −1.31 to −0.39, I²: 77 %), stress (SMD: −0.93, 95 % CI: −1.17 to −0.68, I²: 41 %), and adverse reactions associated with HD (SMD: −0.67, 95 % CI: −0.88 to −0.46, I²: 0 %), all showing strong effect sizes (<em>p</em> &lt; 0.001 for all). However, no significant changes were observed in sleep quality, fatigue, satisfaction with HD, systolic or diastolic blood pressure, heart rate, or finger temperature. A slight reduction in respiration rate (<em>p</em> = 0.0072) and an increase in oxygen saturation (<em>p</em> = 0.0056) were noted. While music therapy showed promising results, the notable heterogeneity in pain and anxiety outcomes suggests careful interpretation, although no significant publication bias was detected.</div></div><div><h3>Conclusion</h3><div>Music therapy has demonstrated encouraging outcomes in improving the well-being of patients undergoing HD, particularly in reducing anxiety, pain, and stress. However, due to notable heterogeneity and methodological issues such as small sample sizes and inconsistent blinding, further high-quality research is needed to confirm these findings and establish more robust evidence.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"86 ","pages":"Article 103090"},"PeriodicalIF":3.3,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142343041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research trends and hotspots of acupuncture therapy for obesity from 2004 to 2023: A bibliometric analysis","authors":"Jinkun Wang ,&nbsp;Kangdi Cao ,&nbsp;Zhaoyi Chen ,&nbsp;Tianli Lyu ,&nbsp;Qiuyu Xia ,&nbsp;Lu Liu ,&nbsp;Bin Li","doi":"10.1016/j.ctim.2024.103092","DOIUrl":"10.1016/j.ctim.2024.103092","url":null,"abstract":"<div><h3>Background</h3><div>Acupuncture has been increasingly used in obese people, yet no bibliometric analysis of acupuncture studies for obesity exists. This bibliometric study analyzed research trends, cooperation, and knowledge dissemination on acupuncture for obesity over the past 20 years to inform future directions.</div></div><div><h3>Objectives</h3><div>To investigate the characteristics, hotspots, and frontiers of global scientific output in acupuncture research for obesity over the past two decades.</div></div><div><h3>Methods</h3><div>We retrieved publications on acupuncture for obesity published from 2004 to 2023 from the Web of Science Core Collection. Using Citespace, VOSviewer, and Bibliometrix, we analyzed and visualized the publications, countries, institutions, authors, journals, and keywords from various angles.</div></div><div><h3>Results</h3><div>A total of 357 articles were retrieved. The results showed that the number of annual publications on acupuncture for obesity has increased over time. China had the most publications (217 articles, 60.87 %), with Chengdu University of Traditional Chinese Medicine (24 articles, 6.72 %) as the most prolific institution. Ergene Neyhan, Huang Wei, and Zhou Zhongyu were the most productive authors (9 articles), and the article published by Cho SH in 2009 was the most cited article (60 citations). The most published journal was Evidence-based Complementary and Alternative Medicine, while the Journal of American Journal of Chinese Medicine was the most frequently cited. Recently, “electroacupuncture” “insulin resistance” and “systematic review” appeared frequently. The research hotspots and trends of acupuncture for obesity mainly focus on interventions, hotspot diseases, and mechanism exploration. According to keyword analysis, randomized controlled trials of catgut embedding and mechanistic studies of gut flora are the trends for future research.</div></div><div><h3>Conclusion</h3><div>Although China is the leading producer, multinational co-operation still needs to be strengthened. Currently, the main interventions for obesity were acupuncture and electroacupuncture, and the hot diseases were obesity combined with polycystic ovary syndrome and metabolic syndrome. In addition, randomised controlled trials of catgut embedding and mechanistic studies of gut flora may be potential directions for future research in the field of acupuncture for obesity.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"86 ","pages":"Article 103092"},"PeriodicalIF":3.3,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142326840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of acupuncture combined with five-element music for people with mild/moderate post-stroke depression: A randomized controlled trial","authors":"Jinglong Sun ,&nbsp;Xia Zhou ,&nbsp;Binbin Ren ,&nbsp;Youhua Guo ,&nbsp;Qifeng Xu ,&nbsp;Qin Wang ,&nbsp;Ziyun Feng ,&nbsp;Qingqing Jia ,&nbsp;Wenwen Li ,&nbsp;Li Li ,&nbsp;Shouqiang Chen","doi":"10.1016/j.ctim.2024.103088","DOIUrl":"10.1016/j.ctim.2024.103088","url":null,"abstract":"<div><h3>Objectives</h3><div>To evaluate the efficacy and safety of acupuncture combined with five-element music (FEM) as an therapeutic strategy for the physical and mental state of Post-stroke depression patients.</div></div><div><h3>Design and setting</h3><div>Multicenter, randomized clinical trial conducted at 3 hospitals in China and enrolling 237 patients with PSD between June 2019 and April 2021. Participants mild/moderate PSD (17-item GRID Hamilton Depression Scale (HAMD) score 7–24) were randomly assigned (1:1) to acupuncture combined with FEM (AFEM) group or cognitive behavioral therapy (CBT) group.</div></div><div><h3>Main outcome measures</h3><div>The primary outcome was change and differences between the groups in HAMD-17 from baseline to week 12. Secondary outcomes included Fugl-Meyer Assessment Scale score and Stroke-Specific Quality of Life Scale (SS-QOL) score.</div></div><div><h3>Results</h3><div>The 237 patients in this intention-to-treat analysis were randomized into either the AFEM group (n=119) or the cognitive behavioral therapy (CBT) group (n=118). Of these 237 participants, 225 (94.9 %) completed all outcome measurements at week 12. The AFEM and CBT groups both showed significant improvement in HAMD-17 from baseline to week 12. Patients in the AFEM group had significantly lower HAMD-17 scores of −3.56 at week 8 (95 % CI,-4.59 to −2.53; p &lt;.001) and −3.50 at week 12 (95 % CI,-4.53 to −2.46; p&lt;.001) than patients in the CBT group. The SS-QOL score improved significantly at week 12. The Fugl-Meyer score was significantly lower in the AFEM group than in the CBT group at week 4, but this difference was not statistically significant upon follow-up at weeks 8 and 12. The incidence of treatment-related adverse events was 2.1 % in the AFEM group, with no serious adverse events reported.</div></div><div><h3>Conclusions</h3><div>The results suggest that acupuncture and five-element music significantly improve the depressive symptoms in this cohort of Chinese PSD patients, and the toxicities were similar with CBP group.</div></div><div><h3>Registration</h3><div>This study registered with the ClinicalTrials.gov Identifier: ChiCTR1900023741.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"86 ","pages":"Article 103088"},"PeriodicalIF":3.3,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142343040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond the spice: The multifaceted role of curcumin in multiple sclerosis management","authors":"Amirhossein Sahebkar,&nbsp;Sepideh Salehabadi,&nbsp;Tannaz Jamialahmadi","doi":"10.1016/j.ctim.2024.103091","DOIUrl":"10.1016/j.ctim.2024.103091","url":null,"abstract":"","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"86 ","pages":"Article 103091"},"PeriodicalIF":3.3,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142323944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}