Herbal medicine for treating psoriasis: A systematic review

IF 3.3 3区医学 Q1 INTEGRATIVE & COMPLEMENTARY MEDICINE

Complementary therapies in medicine Pub Date : 2025-04-08 DOI:10.1016/j.ctim.2025.103173

Melanie Anheyer , Holger Cramer , Thomas Ostermann , Alfred Längler , Dennis Anheyer

{"title":"Herbal medicine for treating psoriasis: A systematic review","authors":"Melanie Anheyer , Holger Cramer , Thomas Ostermann , Alfred Längler , Dennis Anheyer","doi":"10.1016/j.ctim.2025.103173","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>Psoriasis, a chronic skin condition influenced by both genetic and environmental factors, affects approximately 2 % of the global population. Treatment approaches range from topical agents for mild to moderate cases to systemic therapies for moderate to severe forms. Complementary and integrative medicine, including herbal remedies, is increasingly utilized by psoriasis patients, with herbal medicine being the most prevalent choice.</div></div><div><h3>Methods</h3><div>This systematic review adhered to PRISMA guidelines and Cochrane recommendations, with prior registration. Searches were conducted in Medline/PubMed, Scopus, and the Cochrane Central Register of Controlled Trials through June 2024. Inclusion criteria encompassed randomized controlled trials (RCTs) evaluating herbal therapies in psoriasis patients of any age. Data extraction and risk of bias assessment were performed independently by two authors, with discrepancies resolved through discussion.</div></div><div><h3>Results</h3><div>A total of 20 RCTs involving 1115 patients were included. Overall risk of bias varied across studies. Herbal interventions evaluated included Aloe vera, avocado oil, chamomile-pumpkin seed oleogel, indigo naturalis, kukui oil, mahonia aquifolium, turmeric, St. John’s wort, and various complex herbal preparations. Some herbal therapies, such as Mahonia aquifolium and Indigo naturalis, showed promise in reducing psoriasis severity, while others demonstrated mixed results<em>.</em></div></div><div><h3>Conclusions</h3><div>Herbal therapies present a diverse array of options for psoriasis management, but further research is essential to elucidate their safety profile and true effectiveness. Healthcare providers should engage in shared decision-making with patients, considering individual preferences and treatment goals while remaining vigilant in guiding towards evidence-based treatments.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"90 ","pages":"Article 103173"},"PeriodicalIF":3.3000,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Complementary therapies in medicine","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0965229925000482","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"INTEGRATIVE & COMPLEMENTARY MEDICINE","Score":null,"Total":0}

引用次数: 0

Abstract

Background

Psoriasis, a chronic skin condition influenced by both genetic and environmental factors, affects approximately 2 % of the global population. Treatment approaches range from topical agents for mild to moderate cases to systemic therapies for moderate to severe forms. Complementary and integrative medicine, including herbal remedies, is increasingly utilized by psoriasis patients, with herbal medicine being the most prevalent choice.

Methods

This systematic review adhered to PRISMA guidelines and Cochrane recommendations, with prior registration. Searches were conducted in Medline/PubMed, Scopus, and the Cochrane Central Register of Controlled Trials through June 2024. Inclusion criteria encompassed randomized controlled trials (RCTs) evaluating herbal therapies in psoriasis patients of any age. Data extraction and risk of bias assessment were performed independently by two authors, with discrepancies resolved through discussion.

Results

A total of 20 RCTs involving 1115 patients were included. Overall risk of bias varied across studies. Herbal interventions evaluated included Aloe vera, avocado oil, chamomile-pumpkin seed oleogel, indigo naturalis, kukui oil, mahonia aquifolium, turmeric, St. John’s wort, and various complex herbal preparations. Some herbal therapies, such as Mahonia aquifolium and Indigo naturalis, showed promise in reducing psoriasis severity, while others demonstrated mixed results.

Conclusions

Herbal therapies present a diverse array of options for psoriasis management, but further research is essential to elucidate their safety profile and true effectiveness. Healthcare providers should engage in shared decision-making with patients, considering individual preferences and treatment goals while remaining vigilant in guiding towards evidence-based treatments.

查看原文本刊更多论文

求助全文

约1分钟内获得全文求助全文

来源期刊

Complementary therapies in medicine 医学-全科医学与补充医学

CiteScore

8.60

自引率

2.80%

发文量

101

审稿时长

112 days

期刊介绍： Complementary Therapies in Medicine is an international, peer-reviewed journal that has considerable appeal to anyone who seeks objective and critical information on complementary therapies or who wishes to deepen their understanding of these approaches. It will be of particular interest to healthcare practitioners including family practitioners, complementary therapists, nurses, and physiotherapists; to academics including social scientists and CAM researchers; to healthcare managers; and to patients. Complementary Therapies in Medicine aims to publish valid, relevant and rigorous research and serious discussion articles with the main purpose of improving healthcare.