Complementary therapies in medicine最新文献

{"title":"Efficacy and safety of acupuncture for weight management: A systematic review and meta-analysis of randomized controlled trials.","authors":"Yurou Li, Jingya Yang, Yuxiao Li, Hao Hu, Carolina Oi Lam Ung","doi":"10.1016/j.ctim.2025.103171","DOIUrl":"https://doi.org/10.1016/j.ctim.2025.103171","url":null,"abstract":"<p><strong>Introduction: </strong>Obesity is a chronic health problem worldwide, leading to an increased focus on weight management. Acupuncture is widely used in weight loss as traditional and complementary medicine because of its economy, simplicity, and safety. This study aimed to identify the latest evidence on acupuncture for weight loss and evaluate the efficacy and safety of the included randomized controlled trials (RCTs).</p><p><strong>Methods: </strong>Seven databases were searched to identify RCTs published since January 2013 on using acupuncture for weight management. The STRICTA, CONSORT, and Cochrane Collaboration's Risk of Bias tools were used to evaluate the included trials' quality and risk of bias. All eligible trials were included in this meta-analysis.</p><p><strong>Results: </strong>Sixty-four trials were included. Compared to control groups, acupuncture had a significant effect on BMI (mean difference (MD) = -2.15, 95% confidence interval (CI) = -2.86 to -1.44, P < 0.01), body weight (MD = -2.67, 95% CI = -4.07 to -1.28, P < 0.01), waist circumference (MD = -3.61, 95% CI = -4.72 to -2.50, P < 0.01), and some blood test indicators. Serious adverse events were not observed. However, the quality of the included trials was generally poor, and the risk of bias was uncertain.</p><p><strong>Conclusions: </strong>Our study showed that acupuncture is effective for weight management. However, there are no clear conclusions regarding its safety. Studies of higher quality and longer duration are needed to improve the evidence base of acupuncture in weight management for clinical reference.</p>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":" ","pages":"103171"},"PeriodicalIF":3.3,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143794902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Education, Training, and Perceptions of Physician Competency Among Medical Cannabis Patients in Israel.","authors":"Yuval Zolotov, Offer E Edelstein, Leslie Mendoza Temple, Mikhail Kogan, Shai-Li Romem-Porat, Alexander Reznik, Richard Isralowitz","doi":"10.1016/j.ctim.2025.103172","DOIUrl":"https://doi.org/10.1016/j.ctim.2025.103172","url":null,"abstract":"<p><strong>Background: </strong>Medical cannabis use is expanding globally, yet knowledge gaps persist among both patients and healthcare professionals. This study aimed to examine age-related differences in medical cannabis use patterns, sources of education and training, and perceptions of physician competencies among medical cannabis patients in Israel.</p><p><strong>Methods: </strong>A cross-sectional survey of 233 Israeli medical cannabis patients assessed use patterns, education and training sources, and perceptions of physician competencies. Data were analyzed by age groups (18-33, 34-48, 49-64, 65+) using descriptive statistics, chi-square tests, and ANOVA.</p><p><strong>Results: </strong>Use patterns differed significantly by age. Smoking was common among participants aged 18-33 (40%) and 34-48 (37.8%) but less common in the 49-64 group (16.7%) and the 65+ group (10%; p<.001). Conversely, ingestion-based methods were reported by 65.5% of participants aged 65+ and by 72.2% in the 49-64 group, but only by 45.9% and 50% in younger groups (p<.01). Among 57.6% of participants who knew the THC/CBD concentration of their cannabis, mean THC concentration decreased with age (p<0.05), while mean CBD concentration increased with age (p<0.01). Most participants (89.8%) received education on medical cannabis, primarily from physicians (74.7%), but 35.4% used internet sources, and 20.1% reported peer networks.</p><p><strong>Conclusion: </strong>This study identifies age-related differences in medical cannabis use patterns, information sources, and perceptions of physician competencies. Future research should explore how tailored patient education and clinician training can address these differences and improve guidance for medical cannabis use.</p>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":" ","pages":"103172"},"PeriodicalIF":3.3,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143788107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gratitude, compassion, awe, and anticipation.","authors":"Kathi J Kemper","doi":"10.1016/j.ctim.2025.103170","DOIUrl":"10.1016/j.ctim.2025.103170","url":null,"abstract":"","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":" ","pages":"103170"},"PeriodicalIF":3.3,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143751306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to Editor on “Discovery of the microbiota-gut-brain axis mechanisms of acupuncture for amnestic mild cognitive impairment based on multi-omics analyses: A pilot study”","authors":"Wei Pan ,&nbsp;Linan Lin ,&nbsp;Yi Liang","doi":"10.1016/j.ctim.2025.103168","DOIUrl":"10.1016/j.ctim.2025.103168","url":null,"abstract":"","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"90 ","pages":"Article 103168"},"PeriodicalIF":3.3,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143751329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing the effects of different non-pharmacological traditional Chinese medicine therapies on cancer survivors: A Bayesian Network Meta-analysis","authors":"Shaowang Zhang ,&nbsp;Yuanyin Li ,&nbsp;Zhide Liang ,&nbsp;Jiaxing Dai ,&nbsp;Hong Huang ,&nbsp;Huanghui Zhang ,&nbsp;Bing Yang ,&nbsp;Jinghui Wang ,&nbsp;Dongxin Tang","doi":"10.1016/j.ctim.2025.103164","DOIUrl":"10.1016/j.ctim.2025.103164","url":null,"abstract":"<div><h3>Objectives</h3><div>Several studies have demonstrated the positive impact of non-pharmacological Traditional Chinese Medicine (TCM) therapies on pain, fatigue, sleep quality, and quality of life in cancer survivors. However, no research has compared the effectiveness of these therapies. This study aims to compare various interventions and identify the most effective non-pharmacological TCM therapies to provide evidence-based recommendations for cancer survivors.</div></div><div><h3>Methods</h3><div>A systematic search was conducted in PubMed, Embase, Web of Science, CNKI, and Wanfang Data. RCTs investigating the effects of Taichi, Qigong, acupuncture, acupressure, TCM emotional therapy, and mixed therapies as interventions for cancer survivors were screened was conducted. Data from the creation of the database to February 2025 were included. Two independent reviewers evaluated the study quality. A Bayesian Network Meta-analysis was conducted to carry out a random effects model.</div></div><div><h3>Results</h3><div>Seventy-one RCTs involving 6473 patients were included in the analysis. Network meta-analysis showed significance for all five intervention therapies in pain control in cancer patients. The best efficacy was observed for acupressure (SMD=-1.1 [-1.55, −0.66]) and Taichi/Qigong (SMD=-1.08[-1.64, −0.53]), followed by TCM emotional therapy (SMD=-0.93 [-1.42, −0.44]) and acupuncture (SMD=-0.54 [-0.93, −0.15]), with the latter showing comparatively lower efficacy. None of the interventions demonstrated superior efficacy in improving fatigue compared to the control group. Mixed therapies (SMD=-1.36[-2.56, −0.28]) demonstrated the greatest effect in improving sleep quality. Taichi/Qigong (SMD=1.87 [0.96, 2.83]) demonstrated certain advantages in improving quality of life. However, acupuncture and TCM emotional therapy had no significant effect on sleep quality or overall quality of life.</div></div><div><h3>Conclusion</h3><div>The evidence from this study suggests that acupressure and Taichi/Qigong are recommended as the most effective therapies for pain relief and quality of life improvement, respectively. The efficacy of these therapies for fatigue remains inconclusive. However, due to the limited number of included studies and the high risk of bias, these results should be interpreted with caution. Future studies should include more rigorously designed high-quality randomized controlled trials to confirm their long-term efficacy and safety.</div></div><div><h3>Registration</h3><div>PROSPERO CRD42024601976</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"90 ","pages":"Article 103164"},"PeriodicalIF":3.3,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143725689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of aromatherapy with peppermint, ginger, and lavender on postoperative nausea severity after oral surgery under general anaesthesia: A single-blind randomized controlled trial","authors":"Emi Ishikawa,&nbsp;Toshiaki Fujisawa,&nbsp;Yukifumi Kimura,&nbsp;Takayuki Hojo,&nbsp;Nobuhito Kamekura,&nbsp;Kanta Kido","doi":"10.1016/j.ctim.2025.103169","DOIUrl":"10.1016/j.ctim.2025.103169","url":null,"abstract":"<div><h3>Objectives</h3><div>This study aimed to examine whether aromatherapy with peppermint (Mentha piperita Mitcham), ginger (Zingiber officinale), and lavender (Lavandula angustifolia) reduces the severity of nausea in patients experiencing postoperative nausea after oral surgery under general anaesthesia.</div></div><div><h3>Design</h3><div>Single-centre, stratified (volatile inhaled anaesthetics used or not and sex, with balanced randomization), single-blind, placebo-controlled study conducted in Japan.</div></div><div><h3>Setting</h3><div>Hokkaido University Hospital.</div></div><div><h3>Interventions</h3><div>Totally, 182 patients were randomized into two groups of aromatherapy: aroma group comprising three essential oils—peppermint, ginger, and lavender—each diluted to 1 % (each dose as pure essential oil was 0.01 ml) and control group with purified water only. Of these, 32 patients in the aroma group and 25 in the control group complained of postoperative nausea and were treated with intervention.</div></div><div><h3>Main outcome measures</h3><div>Change in nausea severity at the onset of postoperative nausea.</div></div><div><h3>Results</h3><div>Nausea severity before the intervention did not differ between groups. Aromatherapy significantly reduced nausea severity (<em>p</em> &lt; 0.001). The percentages of antiemetics used were 30.77 % and 52.38 % in the aroma and control groups, respectively, with no significant difference. The aroma group showed significantly higher satisfaction (<em>p</em> &lt; 0.001). No adverse events were observed during the study.</div></div><div><h3>Conclusions</h3><div>This study indicated that aromatherapy with peppermint, ginger, and lavender significantly improved patient satisfaction and severity of postoperative nausea after oral surgery under general anaesthesia. Therefore, given the benefits of aromatherapy, it would be advantageous to consider a combination of measures that include aromatherapy, as one of the multimodal antiemetic measures.</div><div>This trial was registered at the Japan Registry of Clinical Trials (jRCTs: 01121002).</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"90 ","pages":"Article 103169"},"PeriodicalIF":3.3,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143714328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interventions used in control group against cupping therapy for chronic nonspecific low back pain: A systematic review and network meta-analysis","authors":"Junyan Li ,&nbsp;Yuanyuan Jia ,&nbsp;Tingting Sun ,&nbsp;Zhenmin Bai ,&nbsp;Xiaosheng Dong ,&nbsp;Xiao Hou","doi":"10.1016/j.ctim.2025.103167","DOIUrl":"10.1016/j.ctim.2025.103167","url":null,"abstract":"<div><h3>Introduction</h3><div>The evidence for the effect of cupping therapy on chronic nonspecific low back pain (CLBP) remains controversial, and existing researches didn’t consider outcomes influenced by factor of selection of interventions in control group. This review and network meta-analysis is to compare the effects of diverse interventions in cupping therapy control groups for CLBP, with the objective of identifying the suitable control intervention against cupping therapy for CLBP.</div></div><div><h3>Methods</h3><div>Studies were identified by a comprehensive search of databases, such as PubMed, Embase, Cochrane Library, Web of Science and China National Knowledge Infrastructure (CNKI), up to June, 2024. A total of 10 randomized control trials (RCT) were included in this network meta-analysis (NMA).</div></div><div><h3>Results</h3><div>The results showed that compared with cupping therapy, minimum negative pressure cupping therapy (MNPCT) (SMD = − 0.01; 95 %CI: − 0.92 to 0.89), air circulating cupping therapy (ACCT) (SMD = − 0.05; 95 %CI: − 0.63 to 0.54) and diclofenac (SMD = − 0.13; 95 %CI: − 1.13 to − 0.87) was no significantly different from improvement of pain intensity. But there was significant difference between cupping therapy and D-ibuprofen (SMD = − 1.11; 95 %CI: − 2.08 to − 0.13), paracetamol (SMD = − 1.12; 95 %CI: − 1.80 to − 0.43) or usual care (SMD = − 1.18; 95 %CI: − 2.56 to − 1.06). The order of intervention effect by SUCRA diagram was as follows: cupping therapy (77.7 %) &gt; MNPCT (75.2 %) &gt; ACCT (73.8 %) &gt; diclofenac (68.8 %) &gt; D-ibuprofen (26.3 %) &gt; paracetamol (24.5 %) &gt; usual care (3.8 %). The quality of evidence for network estimates was moderate to very low due to the risk of bias and imprecision.</div></div><div><h3>Conclusions</h3><div>The results of this study suggest that usual care was the least effective in alleviating the pain intensity of CLBP, which might serve as the most appropriate intervention in the control group in cupping-related RCTs. MNPCT and ACCT have similar effects with cupping therapy for CLBP. Future research may be based on some objective clinical outcomes and control interventions with physiological inertia to isolate the true effect of cupping therapy or SCT from psychological biases.</div></div><div><h3>Trial registration</h3><div>The protocol was registered on the international prospective register of systematic reviews (<span><span>http://www.crd.york.ac.uk/PROSPERO</span><svg><path></path></svg></span>), registration number: CRD42024527513.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"90 ","pages":"Article 103167"},"PeriodicalIF":3.3,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143699848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pharmacokinetic interactions of fruit juices with antihypertensive drugs in humans: A systematic review and meta-analysis","authors":"Janthima Methaneethorn ,&nbsp;Piyameth Dilokthornsakul ,&nbsp;Tippawan Siritientong ,&nbsp;Zheng Jiao ,&nbsp;Wanaporn Chareonchokthavee ,&nbsp;Nattawut Leelakanok","doi":"10.1016/j.ctim.2025.103165","DOIUrl":"10.1016/j.ctim.2025.103165","url":null,"abstract":"<div><h3>Introduction</h3><div>Fruit juice-antihypertensive drug interactions can lead to subtherapeutic or supratherapeutic outcomes. This systematic review and meta-analysis assesses such interactions and their potential clinical relevance.</div></div><div><h3>Methods</h3><div>PubMed, Scopus, and Science Direct databases were searched from their inception through June 2024. Eligible studies were those that investigated the effects of fruit juice on the pharmacokinetics of antihypertensive drugs. <em>I</em>^<em>2</em> was used to determine heterogeneity among studies, and a random effect model was employed for meta-analysis. This review adhered to PRISMA guidelines and was registered in PROSPERO (CRD42022340159).</div></div><div><h3>Results</h3><div>Fifty-one studies were included. Most of them were open-label crossover trials. Grapefruit juice (GFJ), an inhibitor of organic-anion-transporting polypeptide (OATP) transporters and cytochrome P450 (CYP) 3A4, significantly decreased the AUC and C_max of aliskiren and celiprolol by approximately 80–90 %. Conversely, the AUC and C_max of calcium channel blockers decreased with variable degrees when co-administered with GFJ. Apple and orange juices have comparable effects on certain medications. Most studies had small sample sizes and were of moderate quality. Hemodynamic effects were not assessed in most studies; thus, the clinical significance of these interactions remains uncertain and should be further investigated.</div></div><div><h3>Conclusion</h3><div>Co-administration of fruit juice with antihypertensive drugs can result in an increase or decrease in drugs’ bioavailability, depending on the drugs’ metabolism route and the involvement of transporters. Though further studies are needed to confirm clinical relevance in hypertensive patients, it is advised to avoid co-consumption of fruit juice with drugs showing significant changes in pharmacokinetic parameters to prevent subtherapeutic or supratherapeutic effects.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"90 ","pages":"Article 103165"},"PeriodicalIF":3.3,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143691373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is integrating acupuncture into the management of attention-deficit/hyperactivity disorder among children and adolescents now opportune and evidence-based? A systematic review with meta-analysis and trial sequential analysis","authors":"Fei-Yi Zhao ,&nbsp;Yan Xu ,&nbsp;Gerard A. Kennedy ,&nbsp;Russell Conduit ,&nbsp;Wen-Jing Zhang ,&nbsp;Ting Jiang ,&nbsp;Peijie Xu ,&nbsp;Yuen-Shan Ho ,&nbsp;Qiang-Qiang Fu ,&nbsp;Chin-Moi Chow","doi":"10.1016/j.ctim.2025.103163","DOIUrl":"10.1016/j.ctim.2025.103163","url":null,"abstract":"<div><h3>Background and aim</h3><div>The use of acupuncture is becoming increasingly popular in the management of attention-deficit/hyperactivity disorder (ADHD). This systematic review consolidates evidence on acupuncture’s efficacy and safety for treating ADHD in children and adolescents.</div></div><div><h3>Methods</h3><div>Controlled clinical trials assessing acupuncture against waitlist-control, placebo or active controls, or as an adjunct treatment were systematically searched across seven databases from inception to November 2024. Cochrane criteria were adhered to.</div></div><div><h3>Results</h3><div>We reviewed 25 studies with 1758 participants. None compared acupuncture to placebo or behavioral therapy. Subdomain analysis of the Conners’ Parent Rating Scale indicated that acupuncture and Methylphenidate had comparable effects on <em>Conduct Problems</em> [<em>SMD</em> = 0.03, 95 %<em>CI</em> (-0.93, 0.99), <em>p</em> = 0.95] and <em>Learning Problems</em> [<em>SMD</em> = 0.29, 95 %<em>CI</em> (-0.38, 0.97), <em>p</em> = 0.39], but acupuncture was more effective in controlling <em>Impulsive/Hyperactive</em> symptoms [<em>SMD</em> = -1.71, 95 %<em>CI</em> (-2.08, −1.35), <em>p</em> &lt; 0.01]. Insufficient sample size prevented confirmation of potential false positives. Acupuncture was safer and reduced Methylphenidate-related side-effects, including appetite loss, sleep disturbances, dry mouth, abdominal pain, and constipation. Acupuncture combined with behavioral therapy outperformed behavioral therapy alone in improving <em>Psychosomatic</em> symptoms [<em>SMD</em> = -0.88, 95 %<em>CI</em> (-1.54, −0.23), <em>p</em> &lt; 0.01]. In the Integrated Visual and Auditory Continuous Performance Test, ADHD patients receiving acupuncture alongside conventional care performed better than those receiving conventional care alone. Nevertheless, the methodological quality of the included trials was very low to low, with significant bias risk, and 88 % lacked follow-up.</div></div><div><h3>Conclusions</h3><div>Acupuncture may offer an alternative for children and adolescents with ADHD who are intolerant to medication (primarily Methylphenidate). When combined with medication or behavioral therapy, it appeared more effective in ameliorating hyperactivity/impulsivity, inattention and conduct problems than standard treatments alone. It is also safe and well-tolerated. However, the supporting evidence is of low quality, and well-designed randomized controlled trials are needed. Thus, it is premature to recommend acupuncture as an alternative or adjunctive therapy for ADHD management.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"90 ","pages":"Article 103163"},"PeriodicalIF":3.3,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Motor learning-based clinical pilates training for the Parkinson’s disease rehabilitation @Parkinsonpilates: A parallel group, randomised controlled trial with 3-month follow-up","authors":"Fahriye Coban ,&nbsp;Beliz Belgen Kaygisiz ,&nbsp;Ferda Selcuk","doi":"10.1016/j.ctim.2025.103161","DOIUrl":"10.1016/j.ctim.2025.103161","url":null,"abstract":"<div><h3>Objectives</h3><div>To examine the effect of integrated motor learning clinical pilates protocol we developed for patients with Parkinson’s Disease (pwPD) on providing enduring motor skills in walking, balance, reaction time, cadence, and functional mobility at 3-months follow-up.</div></div><div><h3>Design</h3><div>A parallel-group, randomized controlled trial (RCT).</div></div><div><h3>Setting</h3><div>XXX Medical Center, XXX, and XXX Physiotherapy and Rehabilitation Center, Nicosia.</div></div><div><h3>Participants</h3><div>32 pwPD with Hoehn&amp;Yahr stages 2–3 were randomly assigned to the Parkinsonpilates Group (PP) and the Conventional Physiotherapy (CP) Group.</div></div><div><h3>Interventions</h3><div>Both groups received 60 min of training, twice a week, and a home physiotherapy program 4 times a week, for 12 weeks. The intervention group received PP, while the CP group received general physiotherapy training for PD.</div></div><div><h3>Main outcome measures</h3><div>The primary outcomes were untimed Gait and Balance Scale, Cadence, and Nelson Foot Reaction Test scores. The secondary outcomes were The Unified Parkinson's Disease Rating Scale-III subscales, Timed Up and Go Test, Functional Reach Test, and Berg Balance Scale. Outcomes were convened 4 times: pre-test, 6. weeks, post-treatment, and after 3-month follow-up.</div></div><div><h3>Results</h3><div>At post-test, gait and balance, reaction time, functional mobility, static and dynamic balance showed a significant improvement in PP compared to CP, and the motor examination was similar(p &gt; .05). In addition to these results at follow-up, functional mobility was similar(p &gt; .05) and cadence(p &lt; .05) showed a significant improvement in PP. In addition, according to pairwise comparisons, the PP showed a significant improvement in cadence and reaction time in all 4 measures compared to CP.</div></div><div><h3>Conclusions</h3><div>More studies are needed to clarify the effects of the program we developed for PD. It should not be ignored that our protocol can be improved again according to the suggestions of future studies.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"90 ","pages":"Article 103161"},"PeriodicalIF":3.3,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143591771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}