Complementary therapies in medicine最新文献

{"title":"Effective Approaches for Improving Physical Activity in Patients with Chronic Obstructive Pulmonary Disease: An umbrella review.","authors":"Masoumeh Masoumy, Shahnaz Ahrari, Raheleh Javanbakhtian, Seyyed Abolfazl Vagharseyyedin","doi":"10.1016/j.ctim.2026.103462","DOIUrl":"https://doi.org/10.1016/j.ctim.2026.103462","url":null,"abstract":"<p><strong>Background: </strong>Physical inactivity is a significant predictor of hospitalization and all-cause mortality in COPD patients. This study sought to identify the most successful methods for improving physical activity in COPD patients.</p><p><strong>Methods: </strong>Systematic reviews with or without meta-analysis from January 2012 to December 2024 according to the PRISMA 2020 guidelines were included. Searches were conducted in MEDLINE, Web of Science, Cochrane Library and other databases. Selected studies had two quality standards required by the Database of Abstracts of Reviews of Effects and focused on improving physical activity in COPD patients.</p><p><strong>Results: </strong>Ultimately, 20 systematic reviews, with 35,816 participants, were selected for this study. Four main classifications with eleven approaches to improving physical activity were identified. These approaches include: 1. Exercise (Tai Chi, traditional mind-body exercises, walking, and pedometers); 2. Technology-based interventions (Virtual reality-based therapy [VRBT], telerehabilitation [telemonitoring, applications], and smartphone devices, which increased activity by over 18.3% within 6 months and 21% over 12 months, and serious games with a 61.83% adherence rate); 3. Theoretical-behavioral approaches (consultation and coaching, and behavior change interventions); 4. Hybrid approaches.</p><p><strong>Conclusion: </strong>Based on the narrative synthesis, a hybrid approach could be a useful strategy for addressing barriers to physical activity in patients with COPD. Such an approach could include tailoring interventions (e.g., combining tai chi with coaching) and delivering them through technology-based platforms (e.g., VRBT) according to individual patient and health system needs. This approach can improve patients' physical activity levels and support adherence to physical activity, thereby potentially optimizing the treatment process.</p>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":" ","pages":"103462"},"PeriodicalIF":4.0,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149223444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Aromatherapy on The pain-anxiety-Sleep disturbance Symptom Cluster in Breast Cancer Patients A Systematic Review.","authors":"Yiling Yuan, Dan Hu, Jin Tu","doi":"10.1016/j.ctim.2026.103457","DOIUrl":"https://doi.org/10.1016/j.ctim.2026.103457","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate the effectiveness of aromatherapy on the pain-anxiety-sleep disturbance symptom cluster in breast cancer patients.</p><p><strong>Method: </strong>Randomized Controlled Trials were searched in CNKI, Wanfang, PubMed, Scopus, Embase, CINAHL, Web of Science, and Cochrane Library before August 2026. The screening of literature and data extraction were independently completed by two researchers, and the ROB 2 was used to evaluate the risk of bias. A narrative method was used to synthesize the outcomes. This systematic review has been registered(PROSPERO: CRD420251132362).</p><p><strong>Result: </strong>10 articles were included. 7 studies assessed at least two symptoms within the pain-anxiety-sleep disturbance symptom cluster. Effective part of the intervention including the interventions length within 4 weeks, the optimal timing for intervention were in the evening, The intervention time should be limited within 20-30min.</p><p><strong>Conclusions: </strong>Aromatherapy may be a potential adjunctive therapy for alleviating the pain-anxiety-sleep disturbance symptom cluster in breast cancer patients across different treatment phases. But higher-quality studies with rigorous designs and standardized reporting are needed before clinical implementation can be recommended.</p>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":" ","pages":"103457"},"PeriodicalIF":4.0,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149223507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Short-term Efficacy of massage and related treatments for Ankylosing Spondylitis: A Systematic Review and Meta Analysis.","authors":"Yao Shengyang, Lu Siqi, Xu Yangming, Zheng Junjie, Zhu Bowen, Zhu Qingguang, Fang Min, Cheng Yanbin","doi":"10.1016/j.ctim.2026.103455","DOIUrl":"https://doi.org/10.1016/j.ctim.2026.103455","url":null,"abstract":"<p><strong>Background: </strong>Ankylosing spondylitis (AS) is a chronic inflammatory rheumatic disease causing significant pain, stiffness, and functional impairment. Conventional treatments are limited by adverse events and poor efficacy for axial manifestations, leading AS patients to seek complementary therapies such as massage. However, no systematic reviews or meta-analyses have synthesized evidence on massage for AS, leaving its efficacy unconfirmed.</p><p><strong>Methods: </strong>From inception to July 5, 2025, a comprehensive literature search was conducted using eight electronic databases to identify randomized controlled trials of massage and related treatments for AS. Risk of bias was assessed via Cochrane RoB 2, and data was synthesized using Review Manager 5.4. Subgroup analysis was performed according to the different intervention methods. The I2 statistic was used to assess the heterogeneity.</p><p><strong>Results: </strong>Seventeen RCTs involving 1,687 patients were included. Meta-analysis demonstrated that massage significantly improved disease activity (Bath Ankylosing Spondylitis Disease Activity Index [BASDAI]: SMD = -1.09, 95% CI: -1.38 to -0.80, P < 0.001), physical function (Bath Ankylosing Spondylitis Functional Index [BASFI]: SMD = -1.00, 95% CI: -1.33 to -0.67, P < 0.001), spinal pain (Visual Analog Scale [VAS-pain]: MD = -1.43, 95% CI: -1.80 to -1.05, P < 0.001), and inflammatory markers (erythrocyte sedimentation rate [ESR]: MD = -3.58, 95% CI: -4.71 to -2.99, P < 0.001; C-reactive protein [CRP]: SMD = -0.73, 95% CI: -1.03 to -0.43, P < 0.001) compared to control groups. Subgroup analysis suggested that massage alone might be more effective than massage combined with other therapies like acupuncture. Significant heterogeneity was observed, attributable to variations in massage techniques and protocols. Of note, the long-term efficacy of massage was not evaluated in this review, as no included studies provided follow‑up beyond the treatment period.</p><p><strong>Conclusion: </strong>Massage and related treatments are effective in alleviating disease activity, improving physical function, reducing pain, and lowering inflammation in patients with ankylosing spondylitis. It can be considered as a beneficial non-pharmacological adjunct for AS. However, these findings must be interpreted with caution due to several limitations inherent in the included studies, including methodological flaws, small sample sizes, inconsistent treatment protocols, and insufficient statistical precision. Moreover, blinding was not feasible in massage therapy, which precludes exclusion of potential placebo or observer effects. Therefore, future high‑quality, standardized, and longitudinal RCTs are warranted to confirm the role of massage in evidence‑based AS management.</p>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":" ","pages":"103455"},"PeriodicalIF":4.0,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149223512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Evidence of Acupressure for Improving Chemotherapy-Induced Nausea and Vomiting in Breast Cancer Patients: A Systematic Review and Meta-Analysis.","authors":"Xiao-Min Quan, Wen-Yi Wang, Ze-Yu He, Yu Gao, Hong-Yang Chen, Xun Li, Chao An, Qi-Biao Wu, Guan-Hu Yang","doi":"10.1016/j.ctim.2026.103459","DOIUrl":"https://doi.org/10.1016/j.ctim.2026.103459","url":null,"abstract":"<p><strong>Objective: </strong>To systematically evaluate the clinical efficacy of acupressure for chemotherapy-induced nausea and vomiting (CINV) in breast cancer patients, and to provide a reliable evidence-based medical basis for acupressure therapy in the management of CINV in this patient population.</p><p><strong>Methods: </strong>Nine databases were searched for clinical randomized controlled trials (RCTs) on acupressure for the treatment of CINV in breast cancer patients, with the search period ranging from the inception of each database to August 1, 2025. The protocol of this meta-analysis was registered with PROSPERO (registration number: CRD420251119218). Two reviewers independently conducted literature screening and data extraction, and used the Cochrane Risk of Bias Assessment Tool to evaluate the methodological quality of included studies. Statistical analyses were performed using Review Manager 5.4 and Stata 15.0 software, and the GRADE system was applied to assess the evidence quality of outcome measures.</p><p><strong>Results: </strong>A total of 39 studies were included, involving 3501 patients. Meta-analysis results showed that, as an adjuvant therapy to conventional antiemetic drugs, acupressure significantly improved the response rate for CINV relief (acute phase: RR 1.35, 95%CI 1.17 to 1.55; delayed phase: RR 1.41, 95%CI 1.19 to 1.66) and reduced its incidence (acute phase: RR 0.78, 95%CI 0.66 to 0.91; delayed phase: RR 0.58, 95%CI 0.45 to 0.75), with the evidence quality for outcomes in the acute phase rated as moderate. Compared with blank control, acupressure significantly improved patients' anxiety (MD -3.08, 95%CI -4.33 to -1.83) and depression (MD -4.15, 95%CI -4.86 to -3.43) statuses, and increased patient satisfaction (RR 1.24, 95%CI 1.11 to 1.39). However, acupressure alone did not show superiority over conventional antiemetic treatment in terms of most outcomes.</p><p><strong>Conclusion: </strong>This systematic review and meta-analysis found that acupressure, as an adjunct to standard antiemetic regimens, can effectively ameliorate CINV in breast cancer patients-particularly delayed-phase symptoms-and improve patients' mental health and treatment satisfaction. Limited by the methodological quality and heterogeneity of the included studies, the strength of the current evidence requires further enhancement. Future research should conduct more high-quality, standardized clinical trials to further validate its efficacy and provide more robust evidence-based support.</p>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":" ","pages":"103459"},"PeriodicalIF":4.0,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149223477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Empathy in Play Therapy for Children with Mild Intellectual Disabilities: Challenges and Insights.","authors":"Dineke Bent, Martine Noordegraaf, Tine Van Regenmortel","doi":"10.1016/j.ctim.2026.103456","DOIUrl":"https://doi.org/10.1016/j.ctim.2026.103456","url":null,"abstract":"<p><strong>Background and aim: </strong>This article focuses on young people with mild intellectual disabilities who seek assistance in regulating aggression. This assistance includes a treatment program utilizing play therapy. The article aims to contribute to the substantiation of the common and specific factors of play therapy as a treatment method.</p><p><strong>Methods: </strong>The data collection consists of seven cases, each comprising three video-recorded play sessions and reflective interviews with the play therapists. The analysis focuses on the specific micro-interventions employed by the play therapists and the critical aspects of their fundamental therapeutic approach. The article explores how these aspects are utilized to establish the therapeutic relationship, which is considered one of the most important common factors contributing to the impact of play therapy.</p><p><strong>Results: </strong>The results suggest that empathy, as a component of this fundamental stance, warrants greater attention to enhance the therapeutic relationship and, consequently, the overall effectiveness of the treatment.</p><p><strong>Conclusion: </strong>Play therapy is a suitable form of treatment for these young people and their specific needs. It is essential that play therapists can appropriately attune to the individual needs of these young people. The process of raising awareness by articulating emotions and feelings contributes to the regulation of these emotions and feelings.</p>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":" ","pages":"103456"},"PeriodicalIF":4.0,"publicationDate":"2026-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149219961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Traditional Chinese Exercises on Chronic Low Back Pain: A Systematic Review and Network Meta-analysis.","authors":"Handan Zhang, Lijuan Liu, Qiang Wu, Yuxuan Yan, Jun Kou, Chen Du","doi":"10.1016/j.ctim.2026.103458","DOIUrl":"https://doi.org/10.1016/j.ctim.2026.103458","url":null,"abstract":"<p><strong>Background: </strong>Chronic low back pain (CLBP) is a global health problem. Traditional Chinese exercises (TCEs) may relieve pain and improve physical function, but evidence to guide TCE selection remains limited. This study compared the efficacy of different TCEs on pain and functional outcomes in adults with CLBP.</p><p><strong>Methods: </strong>Seven databases and grey-literature sources were searched for randomized controlled trials (RCTs) of TCEs for CLBP from inception to August 2, 2026. Study quality and evidence certainty were assessed using risk-of-bias tools, the NIH Quality Assessment Tool, and the CINeMA framework. Data were analysed using the R package gemtc, standardized mean differences (SMDs) with 95% credible intervals (CrIs) were calculated.</p><p><strong>Results: </strong>Forty-three RCTs involving four TCE modalities were included. On the Visual Analogue Scale (VAS), statistically significant pain reduction was only observed for TCEs combined with conventional therapy (CT); Yijinjing+CT showed the largest numerical effect, followed by Taichi+CT and Baduanjin+CT. Significant Oswestry Disability Index (ODI) improvements occurred with Baduanjin+CT and Wuqinxi+CT. Baduanjin+CT, Wuqinxi+CT, and Yijinjing+CT improved Japanese Orthopaedic Association (JOA) scores. Evidence certainty was low-to-moderate across outcomes.</p><p><strong>Conclusion: </strong>TCE+CT produced large effect estimates for CLBP-related pain and physical function. Although surface under the cumulative ranking curve (SUCRA) rankings favoured Yijinjing+CT for pain relief and Wuqinxi+CT for functional improvement, no statistically significant head-to-head differences were identified among effective combined regimens, precluding definitive ranking of superiority. Given low-to-moderate certainty, clinical decisions should consider patient preferences and intervention accessibility.</p>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":" ","pages":"103458"},"PeriodicalIF":4.0,"publicationDate":"2026-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149215098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multidimensional clinical benefits of cinnamon leaf oil inhalation in primary and metastatic brain tumor patients during winter: A randomized controlled trial.","authors":"Qiang Zhang, Yifan Zhao, Xiaoping Man, Dongwei Yan","doi":"10.1016/j.ctim.2026.103449","DOIUrl":"10.1016/j.ctim.2026.103449","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To evaluate the multidimensional efficacy of 12‑week cinnamon leaf oil (CLO) inhalation as a seasonal adjuvant supportive‑care intervention for alleviating winter‑exacerbated non‑motor symptom burden and improving mood disorders, sleep quality, refractory fatigue, and functional independence in patients with primary and metastatic brain tumors.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;This randomized, controlled clinical trial enrolled 328 patients diagnosed with primary or metastatic brain tumors, randomly assigned at a 1:1 ratio to intervention group (standard antitumor care plus 12‑week undiluted CLO inhalation, 2 h/day, 5 days/week, n = 165) or control group (standard care plus distilled‑water‑vapor sham‑aromatherapy control, n = 163). Baseline demographic and clinical characteristics were descriptively summarized for both groups. The primary outcome was the change in HAM-D total score from baseline to week 12. Secondary outcome indicators included changes in anxiety (HAM‑A), sleep quality (PSQI), physical/mental fatigue (FS-14), and activities of daily living (ADL-BI). Integrated multidimensional outcome profiling was further performed to examine changes across six clinical domains.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Twelve weeks of CLO inhalation was associated with improvements across the assessed outcome measures, whereas the control group receiving only standard care showed minimal clinical changes. The intervention group showed reductions in emotional symptoms, with HAM‑A scores decreasing from 17.65 ± 4.48-12.25 ± 4.51 (p &lt; 0.001) and HAM‑D scores declining from 22.10 ± 5.41-13.68 ± 2.71 (p &lt; 0.001). Improvements in sleep quality were observed, with PSQI total scores dropping from 12.18 ± 3.05-5.25 ± 1.86 (p &lt; 0.01). Additionally, the CLO group showed changes in functional independence, with ADL‑BI total scores increasing from 63.60 ± 14.16-74.88 ± 11.33 (p &lt; 0.01). In terms of fatigue relief, the proportions of patients with severe physical and mental fatigue decreased by 46% and 76%, respectively (p &lt; 0.01). Multidimensional profiling indicated favourable changes for CLO inhalation across sleep, anxiety, depression, physical fatigue remission, mental fatigue remission and daily function. Only mild Grade 1 transient mucosal irritation adverse events occurred in the intervention group with low incidence; no severe adverse reactions or trial withdrawal were observed.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;Findings from this single‑centre trial suggest that 12‑week standardized CLO inhalation may represent a tolerable non‑pharmacological adjuvant approach for brain tumour patients. It was associated with reductions in winter‑exacerbated anxiety, depression, sleep disturbance, and refractory fatigue, as well as improvements in patients' functional independence. Observations of multi‑domain symptom changes warrant further clinical investigation to evaluate its utility within neuro‑oncological supportive‑care practice and pat","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":" ","pages":"103449"},"PeriodicalIF":4.0,"publicationDate":"2026-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149215154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative effectiveness of turmeric and curcumin formulations on glycemic, lipid, and inflammatory markers in people with prediabetes: A systematic review and network meta-analysis.","authors":"Phatcharaporn Khongphakdee, Jaruwan Jumnianpol, Panupong Puttarak, Ratree Sawangjit, Sudathip Sae-Tan","doi":"10.1016/j.ctim.2026.103453","DOIUrl":"https://doi.org/10.1016/j.ctim.2026.103453","url":null,"abstract":"<p><p>Prediabetes is a growing global health concern associated with higher risk of diabetes and cardiovascular disease. Curcumin has been studied for glycemic, lipid, and inflammatory effects, but comparative data across formulations remain limited. This network meta-analysis (NMA) evaluated turmeric and curcumin formulations in adults with prediabetes. Seven databases were searched for randomized controlled trials (RCTs) comparing turmeric/curcumin formulations with placebo. Primary outcomes included glycemic, lipid, and inflammatory markers. Two reviewers independently extracted data and assessed risk of bias. NMAs with surface under the cumulative ranking curve (SUCRA) were performed. Twenty-four RCTs (25 publications, 1,952 participants; mean baseline fasting blood sugar (FBS): 110.3mg/dL) evaluating eight curcumin-based formulations were included. Turmeric extract combined with other compounds (EC) and turmeric extract (E) were associated with significant reductions in FBS with WMD -10.73 (95%CI: -14.22, -7.25;SUCRA 92.2%), and -10.57 (95%CI: -14.35, -6.79;91.5%;SUCRA 91.5%), respectively. E was associated with a significant reduction in HbA1c, while EC was associated with lower HOMA-IR with MWD -0.73 (95%CI: -1.41, -0.05; SUCRA 79.8%). Whole turmeric with other compounds (WC) was associated with a significant reduction in LDL-C (WMD: -37.19, 95%CI: -56.97, -17.42; SUCRA: 97.3%). E was associated with a lower risk of incident type 2 diabetes (RR= 0.05; 95%CI:0.00,0.78), although this estimate was based on low-certainty of evidence. No significant effects were observed for inflammatory markers. Overall certainty of evidence was low due to heterogeneity and short trial durations, and variability among combination formulations. In prediabetes, formulation-specific metabolic effects were observed. However, given the low certainty of evidence, these findings should be interpreted cautiously and confirmed in larger, longer-term trials before clinical recommendation can be made.</p>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":" ","pages":"103453"},"PeriodicalIF":4.0,"publicationDate":"2026-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149215101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of music on the management of anxiety and stress in patients in the preoperative period of Coronary Transluminal Angioplasty: A randomized clinical trial.","authors":"Francisco de Cássio de Oliveira Mendes, Kauanny Vitoria Gurgel Dos Santos, Maria Améllia Lopes Cabral, Danielle de Oliveira Rocha, Mariana Pereira da Silva Araújo, Renata Silva Santos, Késsya Dantas Diniz, Kátia Regina Barros Ribeiro, Daniele Vieira Dantas, Rodrigo Assis Neves Dantas","doi":"10.1016/j.ctim.2026.103454","DOIUrl":"https://doi.org/10.1016/j.ctim.2026.103454","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the effect of music on the management of anxiety and stress in patients awaiting coronary transluminal angioplasty.</p><p><strong>Method: </strong>A double-blind, randomized controlled clinical trial was conducted according to the Consolidated Standards of Reporting Trials (CONSORT) guidelines. The study was carried out at the hemodynamics unit of the Onofre Lopes University Hospital from August to December 2024, with 52 participants equally divided into an intervention and a control group. Both groups were fitted with headphones before the procedure, but only patients in the intervention group were exposed to music. Data were collected using a sociodemographic and clinical data form, the Beck Anxiety Inventory, and Lipp's Stress Symptoms Inventory for Adults.</p><p><strong>Results: </strong>Although there were no significant reductions in the intergroup analysis, the intragroup analysis showed that music influenced a reduction in anxiety and heart rate in the intervention group. However, there was no evidence of an effect of music on stress.</p><p><strong>Conclusion: </strong>No significant reductions were identified in the levels of anxiety and stress of the participants in this research. It is also suggested that the use of headphones without music may have a relaxing effect by muffling external sounds, which possibly masked relevant statistical differences.</p><p><strong>Trial and protocol registration: </strong>Brazilian Clinical Trials Registry: RBR-5jy7kzj (https://ensaiosclinicos.gov.br/rg/RBR-5jy7kzj).</p>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":" ","pages":"103454"},"PeriodicalIF":4.0,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149206706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acupuncture Combined with Auriculotherapy as Adjunctive Therapy for Hyperemesis Gravidarum: A Randomized Controlled Trial Evaluating Hospital Stay, Relapse Rate, and Quality of Life.","authors":"Xia Wang, Lexia Zhang, Shuai Chen, Yamin Zeng, Ji Zheng, Qiaoling Wang, Hongmei Xu","doi":"10.1016/j.ctim.2026.103448","DOIUrl":"https://doi.org/10.1016/j.ctim.2026.103448","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the efficacy of acupuncture combined with auricular therapy as an adjunct to standard fluid resuscitation in patients with hyperemesis gravidarum (HG).</p><p><strong>Methods: </strong>A total of 122 HG patients were randomly assigned to the acupuncture combined (AC) group (n=61) or standard fluid (SF) group (n=61). The SF group received conventional fluid replacement alone, while the AC group received acupuncture and auricular therapy in addition to fluid resuscitation. Primary outcomes included the Pregnancy-Unique Quantification of Emesis and Nausea (PUQE) score, the Functional Living Index-Emesis (FLIE) score (total and subscores), serum potassium, length of hospital stay, and recurrence frequency; secondary outcomes included the Self-Rating Anxiety Scale (SAS) and Self-Rating Depression Scale (SDS) scores. Within-group changes and between-group differences were analyzed using paired t-tests and analysis of covariance (ANCOVA) or Mann-Whitney U tests, respectively.</p><p><strong>Results: </strong>Both groups exhibited significant within-group improvements in PUQE, FLIE, nausea, vomiting, SAS and SDS scores (all p<0.001), with no meaningful change in serum potassium. Post-treatment between-group comparisons, assessed by analysis of covariance adjusted for baseline values, showed significant advantages for adjuvant acupuncture combined with auriculotherapy in total FLIE score (adjusted mean difference -4.11, 95%CI -8.15 to -0.07, p=0.046), nausea subscore (adjusted mean difference -2.11, 95%CI -4.01 to -0.22, p=0.029), SAS (adjusted mean difference -1.04, 95%CI -2.07 to -0.01, p=0.049) and SDS (adjusted mean difference -1.61, 95%CI -3.12 to -0.10, p=0.037), but no significant differences in PUQE, vomiting subscore or serum potassium. The AC group had a shorter median hospital stay (4 vs 6 days, p=0.041) and lower recurrence frequency (0.15 ± 0.441 vs 0.39 ± 0.759, p=0.048). The proportion of participants with recurrence was 11.48% in the AC group and 24.59% in the SF group, with no significant difference (p=0.068).</p><p><strong>Conclusion: </strong>While standard fluid resuscitation effectively relieves the core symptoms of HG, adjunctive acupuncture combined with auriculotherapy provided additional benefits regarding quality of life, psychological status, hospital stay, and recurrence frequency, although no significant intergroup difference was observed in post-treatment PUQE scores or the proportion of patients experiencing HG recurrence. This combined intervention may serve as a safe and valuable adjunctive strategy for HG management. Further sham-controlled trials are required to distinguish specific treatment effects from non-specific contextual factors.</p>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":" ","pages":"103448"},"PeriodicalIF":4.0,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149206660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}