{"title":"The impact of music on anxiety, pain, and blood pressure in ophthalmic surgery: A systematic review and meta-analysis","authors":"Xue Chen , Long Chen , Yin Gao","doi":"10.1016/j.ctim.2024.103062","DOIUrl":"10.1016/j.ctim.2024.103062","url":null,"abstract":"<div><h3>Objectives</h3><p>To evaluate the effectiveness of music therapy in reducing anxiety, pain, and vital sign changes in ophthalmic surgery patients.</p></div><div><h3>Methods</h3><p>An extensive search of databases, including PubMed, Embase, Cochrane, Web of Science, and Google Scholar, identified relevant studies up to Jan 2024. Selection of studies was conducted based on the PICOS criteria. The quality of methodology was assessed using the Cochrane risk-of-bias assessment tool and Review Manager 5.4. Meta-analysis comparing the control group and the music therapy group was performed using R and Stata/SE 15.1 random or fixed effects model.</p></div><div><h3>Results</h3><p>This meta-analysis included fifteen studies comprising 2098 participants. The analysis revealed that music therapy significantly reduced the risk of high anxiety levels as measured by Visual Analogue Scale (VAS) (I<sup>2</sup> = 0 %, RR(95 %CI): 0.75(0.63, 0.88), <em>p</em> = 0.0006), indicating a substantial effect without heterogeneity. The Anxiety scores determined by State-Trait Anxiety Inventory-State (STAI-S) also showed a significant decrease (SMD(95 %CI): −0.75(−0.88, −0.61), <em>p</em> < 0.0001), albeit with moderate heterogeneity (I² = 36 %). Additionally, music therapy was associated with a reduction in intraoperative pain levels, with no observed heterogeneity (I<sup>2</sup> = 0 %, SMD(95 %CI): −0.74(−0.93, −0.56), <em>p</em> < 0.0001). In contrast, music intervention did not significantly influence self-reported nervousness, relaxation, or satisfaction levels as determined by VAS. Regarding to physiological parameters, a marginal decrease in systolic blood pressure (SBP) was observed (SMD(95 %CI): −0.42(−0.79, −0.04), <em>p</em> = 0.0286), with considerable heterogeneity (I² = 92 %). Diastolic blood pressure (DBP) experienced a slight reduction (I² = 90 %, SMD(95 %CI): −0.45(−0.79, −0.11), <em>p</em> = 0.0088). However, no significant effect was observed on patients’ heart rate (<em>p</em> = 0.0864).</p></div><div><h3>Conclusion</h3><p>Music therapy effectively reduced anxiety and pain, and moderately improved vital signs in patients undergoing ophthalmic surgery, highlighting its role in enhancing patient well-being. Further in-depth RCTs are needed to confirm its efficacy.</p></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"83 ","pages":"Article 103062"},"PeriodicalIF":3.6,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0965229924000505/pdfft?md5=9563390f1b06a2e4045408d4c6cb02d7&pid=1-s2.0-S0965229924000505-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141283225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Han-Gyul Lee , Hyein Jeong , Chan-Young Kwon , Kyeong-Han Kim , Soo Hyun Sung , Ji Eun Han , Minjung Park , Soobin Jang
{"title":"Adverse events of herbal decoction: A systematic review and meta-analysis over past 10 years","authors":"Han-Gyul Lee , Hyein Jeong , Chan-Young Kwon , Kyeong-Han Kim , Soo Hyun Sung , Ji Eun Han , Minjung Park , Soobin Jang","doi":"10.1016/j.ctim.2024.103057","DOIUrl":"10.1016/j.ctim.2024.103057","url":null,"abstract":"<div><h3>Background</h3><p>Herbal decoctions (HDs) are the oldest and most common herbal medicine formulations. Different HDs exist, and some consumers are concerned that they may become contaminated during manufacturing. Therefore, the need for a safety assessment of HDs has been raised. This study aimed to investigate the adverse events (AEs) associated with HDs by comprehensively analyzing randomized controlled trials (RCTs) using systematic reviews and meta-analyses.</p></div><div><h3>Methods</h3><p>A systematic search was conducted on PubMed, Embase, and the Cochrane Library for articles published up to November 2022. The included RCTs compared HDs with other treatments published between 2013 and 2022, and the risk of bias was assessed using RevMan 5.4. Meta-analyses of the number of AEs associated with HDs reported in the included RCTs were also performed.</p></div><div><h3>Results</h3><p>The systematic review included 26 RCTs, and the meta-analysis included 17 RCTs that reported AEs. The meta-analysis comparing HDs with active controls showed that both the number of AEs (14 studies; risk ratio (RR)= 0.50 cases, 95 % confidence interval (CI) [0.29, 0.88]; I<sup>2</sup> = 42 %) and the number of patients who complained of AEs (seven studies; RR=0.51 patients, 95 % CI [0.28, 0.94]; I<sup>2</sup> =9 %) were fewer in the HDs group than in the active control groups.</p></div><div><h3>Conclusion</h3><p>This study showed that HDs are safer than other conventional medications based on the results of qualitative and quantitative syntheses of RCTs.</p></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"83 ","pages":"Article 103057"},"PeriodicalIF":3.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0965229924000451/pdfft?md5=4ff6fcc836b26edc81e32a5a7a6954a0&pid=1-s2.0-S0965229924000451-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141234524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Natalia Shania Francis , Yang Mooi Lim , Sumaiyah Mat , Annaletchumy Loganathan
{"title":"Effectiveness of herbs taken concurrently with antihypertensive drugs in managing hypertension and lipid outcomes. A systematic review and meta-analysis.","authors":"Natalia Shania Francis , Yang Mooi Lim , Sumaiyah Mat , Annaletchumy Loganathan","doi":"10.1016/j.ctim.2024.103058","DOIUrl":"10.1016/j.ctim.2024.103058","url":null,"abstract":"<div><h3>Purpose</h3><p>Hypertension is the primary cause of mortality. Hence globally, there is a growing interest in complementing antihypertensive drugs with herbs to alleviate blood pressure among hypertensive patients. Thus, this review aimed to evaluate the effectiveness of complementing drugs with herbs on blood pressure and lipid profile outcomes, the associated factors and the types of complementary herbs alongside their consumption regimes.</p></div><div><h3>Methods</h3><p>This review is registered in PROSPERO on the National Institute of Health Database with an ID: CRD42021270481. Using the PICOS (population, intervention, comparison, outcome, study type) mnemonic formula and search strategy, we searched (January 2010 to February 2024) five electronic databases including Pubmed, Scopus, Web of Science, CINAHL (Cumulative Index for Nursing and Allied Health Literature) and Psychology & Behavioral Sciences Collection (PBSC). The inclusion criteria of the review were that all included papers had to be randomised control trials in English among hypertensive adults who complemented antihypertensive drugs with herbs. A Cochrane risk of bias assessment as well as a meta-analysis and narrative synthesis were conducted to answer the objectives.</p></div><div><h3>Results</h3><p>Twenty-five randomised controlled trials involving 1996 participants from 14 countries were included. The risk of bias among included articles was assessed and presented using the Cochrane risk of bias tool and the graphs were generated. The effects of complementing antihypertensive drugs with different herb regimes on blood pressure and lipid profile outcomes were compared to those solely on antihypertensive drugs and placebo via a random model effects meta-analysis using the Revman manager. Systolic blood pressure (SBP) and triglycerides gave a significant reduction in favour of the intervention group which complemented herbs. The overall pooled systolic blood pressure showed a reduction of (SMD=0.81, 95 % CI 0.14–1.47, <em>p</em> < 0.02, <em>p</em> for heterogeneity=0.00001, I<sup>2</sup> =97 %) while triglycerides were (SMD=0.73, 95 % CI 0.17–1.28, <em>p</em> < 0.01, <em>p</em> for heterogeneity=0.00001, I<sup>2</sup> =85 %). However, diastolic blood pressure, total cholesterol, HDL and LDL did not exert significant outcomes.</p></div><div><h3>Conclusion</h3><p>The complemented herbs with antihypertensive drugs did show improvement in overall blood pressure management in the majority of the studies compared to the placebo group. Blood pressure and lipid profiles are the health outcomes that enable access to complementing herbs in controlling high blood pressure. Some limitations of this review are attributed to performance, detection and attrition bias in a few included articles alongside the presence of a high heterogeneity overall.</p></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"83 ","pages":"Article 103058"},"PeriodicalIF":3.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0965229924000463/pdfft?md5=f89493eb6b1f8cab1da8045ffd0270d6&pid=1-s2.0-S0965229924000463-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141237137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P.S. Deo , T.M. Barber , C. Gotts , M. Villarreal , H. Randeva , S. Brown , J. Bath , P. O’Hare , S. Chaggar , P. Hanson
{"title":"A pilot study to assess the feasibility and uptake of MindDEC, a mindfulness-based self-management course for type 2 diabetes","authors":"P.S. Deo , T.M. Barber , C. Gotts , M. Villarreal , H. Randeva , S. Brown , J. Bath , P. O’Hare , S. Chaggar , P. Hanson","doi":"10.1016/j.ctim.2024.103059","DOIUrl":"10.1016/j.ctim.2024.103059","url":null,"abstract":"<div><h3>Objective</h3><p>The study aimed to investigate the feasibility of a remote mindfulness based self-management intervention for individuals with type 2 diabetes. It is important to further our understanding of how to improve self-management to improve health outcomes and low levels of uptake to self-management courses.</p></div><div><h3>Method</h3><p>29 participants with type 2 diabetes were recruited from the University Hospital Coventry and Warwickshire NHS trust. Three groups of participants engaged with a remote mindfulness based self-management intervention, which were delivered sequentially. After each intervention was complete, patient feedback was retrieved and implemented into the following intervention. The quantitative analysis comprised of descriptive statistics, independent sample t-test, paired sample t-test and multiple regression analysis. A qualitative analysis was also conducted through reflexive thematic analysis (RTA) to understand participant’s perspective on the intervention.</p></div><div><h3>Results</h3><p>There was a total of 17 who attended the course (59 %) and a total drop out of 12 participants over the three courses (41 %). The qualitative findings reported three main themes: (1) Eating to manage my emotions rather than my diabetes (2) Implementing mindfulness has helped me manage my emotions (3) Medication rather than self-management behaviours control my diabetes. The focus group feedback included participants’ appreciation of the community aspect of the intervention and their perception that the current course was more interactive compared to previous interventions. In addition, participants highlighted the importance of offering the course at an earlier stage of diagnosis to provide further support at the beginning of their diabetes journey. No significant findings were reported for the independent sample t-test, paired sample t-test and multiple regression analysis.</p></div><div><h3>Conclusion</h3><p>The qualitative findings suggested that the course was beneficial, especially in demonstrating how mindfulness could aid self-management for individuals living with type 2 diabetes. Further funding and trials are warranted to improve the quality of technology used and to assess impact on diabetes control and mental health.</p></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"83 ","pages":"Article 103059"},"PeriodicalIF":3.6,"publicationDate":"2024-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0965229924000475/pdfft?md5=f69418341ed4e5d6fa7b65a80de54106&pid=1-s2.0-S0965229924000475-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141183811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lili Yang , Xiaorui Liu , Wen Yang , Siqi Wang , Zimu Li , Yiming Lei , Dongling Liu
{"title":"Effect of shenmai injection on anthracycline-induced cardiotoxicity: A systematic review and meta-analysis","authors":"Lili Yang , Xiaorui Liu , Wen Yang , Siqi Wang , Zimu Li , Yiming Lei , Dongling Liu","doi":"10.1016/j.ctim.2024.103053","DOIUrl":"10.1016/j.ctim.2024.103053","url":null,"abstract":"<div><h3>Objective</h3><p>Shenmai injection is a classic herbal prescription, and is often recommended for the treatment of anthracycline-induced cardiotoxicity. However, the efficacy and safety of Shenmai injection for the treatment of anthracycline-induced cardiotoxicity have not been reported.</p></div><div><h3>Materials and methods</h3><p>We conducted a comprehensive search of eight literature databases and two clinical trial registries, retrieving all randomized controlled trials (RCTs) related to the treatment of anthracycline-induced cardiotoxicity with Shenmai injection from the establishment of the databases to July 1, 2023. Data analysis was performed using the Meta package in RStudio and RevMan 5.4. The GRADE pro3.6.1 software was utilized for assessing the quality of evidence.</p></div><div><h3>Results</h3><p>A total of 16 RCTs including 2140 patients were included in this study. Meta-analysis showed that Shenmai injection had an advantage in improving ST-T segment changes (RR = 0.28; 95 % CI, 0.20 to 0.39; <em>P</em> < 0.0001) (<em>P</em> < 0.01), creatine kinase isoenzyme (SMD = −3.49; 95 % CI, −5.24 to −1.74; <em>P</em> < 0.0001), Prolonged QT interval (RR = 0.46; 95 % CI, 0.28 to 0.75; <em>P</em> = 0.0018), Low QRS Voltage (RR = 0.44; 95 % CI, 0.27 to 0.71; <em>P</em> = 0.0007), sinus tachycardia (RR = 0.41; 95 % CI, 0.28 to 0.60; <em>P</em> < 0.0001), atrial premature beats (RR = 0.55; 95 % CI, 0.35 to 0.87; <em>P</em> = 0.01), Premature Ventricular Contractions (RR = 0.39; 95 % CI, 0.26 to 0.59; <em>P</em> < 0.0001) and creatine kinase (SMD = −1.43; 95 % CI, −2.57 to −0.29; <em>P</em> < 0.0001) in patients with anthracycline-induced cardiotoxicity. advantage, which was supported by sensitivity analyses, but not in improving left ventricular ejection fraction (MD = 16.01; 95 % CI, −3.10 to 35.12; <em>P</em> = 0.10) and atrioventricular block (RR = 0.49; 95 % CI, 0.24 to 1.03; <em>P</em> = 0.06). The literature included in the study did not refer to data regarding the safety aspects of Shenmai injection, so we do not yet know the safety of Shenmai injection. The results of subgroup analyses suggested that heterogeneity was not related to the administered dose and chemotherapy regimen. The publication bias test showed no publication bias. The quality of evidence for the results ranged from “very low” to “moderate.”</p></div><div><h3>Conclusion</h3><p>This study suggests that Shenmai injection is effective in treating anthracycline-induced cardiotoxicity and is a potential treatment for anthracycline-induced cardiotoxicity. However, due to the poor methodological quality of the included RCTs, we recommend rigorous, high-quality, large-sample trials to confirm our findings.</p></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"83 ","pages":"Article 103053"},"PeriodicalIF":3.6,"publicationDate":"2024-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0965229924000414/pdfft?md5=33a424fe527865aa08fc5af53ce617e3&pid=1-s2.0-S0965229924000414-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141157847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The influence of traditional Thai massage on recovery from gastrocnemius muscle fatigue: A single-blind randomised controlled trial","authors":"Vitsarut Buttagat, Sujittra Kluayhomthong, Pattanasin Areeudomwong","doi":"10.1016/j.ctim.2024.103056","DOIUrl":"10.1016/j.ctim.2024.103056","url":null,"abstract":"<div><h3>Objective</h3><p>To determine the effects of traditional Thai massage (TTM) on improving fatigue recovery and fatigue-related parameters of the gastrocnemius muscle after a heel-raise exercise.</p></div><div><h3>Design</h3><p>A single-blind randomised controlled trial.</p></div><div><h3>Setting</h3><p>Mae Fah Luang University Hospital, Thailand.</p></div><div><h3>Participants</h3><p>Fifty-four healthy participants were randomly assigned to two groups: TTM (n = 27; 51.85 % women; mean age 23.15 ± 4.90 years; number of exercises/week: 4.78 ± 1.58) and control (n = 27; 59.26 % women; mean age 22.63 ± 4.88 years; number of exercises/week: 4.48 ± 1.25).</p></div><div><h3>Interventions</h3><p>After the participants performed a heel-raise exercise to induce fatigue of the gastrocnemius muscle, they received either 30 min of TTM to the gastrocnemius muscle or 30 min of control (29 min of rest and 1 min total gastrocnemius stretching).</p></div><div><h3>Outcome measures</h3><p>The outcome measures were the median frequency (MDF) of the electromyography signal, muscle power (MP) and feelings of muscle fatigue (FMF). All the outcome measures were evaluated before (T1) and after (T2) the fatigue-inducement protocol as well as immediately (T3), 1 h (T4) and 2 h (T5) after the interventions.</p></div><div><h3>Results</h3><p>The results show that MDF and MP were significantly increased and FMF significantly decreased in both groups immediately after the interventions and at 1 h and 2 h after the interventions (repeated measures ANOVA: <em>p</em> < .05). In the between-group comparisons, participants in the TTM group showed significantly greater improvement than those in the control group on all outcomes at all post-intervention assessment time points (T3, T4, T5), reflecting faster recovery from muscle fatigue (ANCOVA: <em>p</em> < .05).</p></div><div><h3>Conclusion</h3><p>TTM proved an effective intervention for maximising recovery from fatigue of the gastrocnemius muscle.</p></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"83 ","pages":"Article 103056"},"PeriodicalIF":3.6,"publicationDate":"2024-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S096522992400044X/pdfft?md5=f4805386e5da6f487c24ecb26e2dfd83&pid=1-s2.0-S096522992400044X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141143840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammad Abbasian Josheghani, Zahra Tagharrobi, Khadijeh Sharifi, Zahra Sooki, Fatemeh Zare Joshaghani, Mohammad Zare
{"title":"The effects of auriculotherapy on depression among elderly people: A randomized controlled clinical trial","authors":"Mohammad Abbasian Josheghani, Zahra Tagharrobi, Khadijeh Sharifi, Zahra Sooki, Fatemeh Zare Joshaghani, Mohammad Zare","doi":"10.1016/j.ctim.2024.103054","DOIUrl":"10.1016/j.ctim.2024.103054","url":null,"abstract":"<div><h3>Background</h3><p>Given the high prevalence of depression in elderly people, appropriate interventions are essential. This study aimed to assess the effects of auriculotherapy on depression among elderly people.</p></div><div><h3>Methods</h3><p>This randomized controlled clinical trial was conducted in 2021. Fifty-two elderly were conveniently selected and randomly allocated to the sham (n = 26) and intervention (n = 26) groups through block randomization. The intervention group was subjected to four weeks of auriculotherapy at the Shen-Men, zero, heart, antidepressant, and master cerebral points using Vaccaria seeds fixed with adhesive tape. In the sham group, adhesive tapes were attached to the points with neither seeds nor compression. The elderly and data collector were blinded. The 15-item Geriatric Depression Scale was used to assess depression before, immediately after, and four weeks after the intervention (T1–T3). The statistical methods used were repeated measures analysis of variance and covariance.</p></div><div><h3>Results</h3><p>Groups significantly differed concerning participants' gender, education, and employment (p < 0.05). After adjusting for confounding effects, the time-group interaction significantly affected the mean depression score (p < 0.0001, effect size = 0.54). There was no significant difference between the depression score in the sham and intervention groups at T1 (9.6 ± 2.5 vs 9.5 ± 2.5, p = 0.263); however, this difference was found to be significant at T2 (8.6 ± 2 vs 4.2 ± 1.2, p < 0.0001, effect size = 0.68) and T3 (9.3 ± 2.3 vs 4.3 ± 1.3, p < 0.0001, effect size = 0.65). Within-group analysis revealed significant differences in the depression scores of the intervention group at T1 compared with those at T2 and T3 (p < 0.05). In contrast, the mean depression score in the sham group at T2 was significantly lower than that at T1 (p = 0.003) and greater than that at T3 (p = 0.049).</p></div><div><h3>Conclusions</h3><p>Auriculotherapy alleviates depression and can be used as a complementary therapy for elderly people with depression.</p></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"83 ","pages":"Article 103054"},"PeriodicalIF":3.6,"publicationDate":"2024-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0965229924000426/pdfft?md5=800eaccbafe39ed8d736d6cd18d7fc73&pid=1-s2.0-S0965229924000426-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141092902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yuantao Hou , Hansheng Liang , Cungang Fan , Ruen Liu , Yi Feng
{"title":"Transcutaneous electrical acupoint stimulation to prevent dizziness after microvascular decompression for hemifacial spasm: A randomized controlled trial","authors":"Yuantao Hou , Hansheng Liang , Cungang Fan , Ruen Liu , Yi Feng","doi":"10.1016/j.ctim.2024.103055","DOIUrl":"10.1016/j.ctim.2024.103055","url":null,"abstract":"<div><h3>Background</h3><p>Dizziness often occurs after microvascular decompression (MVD), and therapeutic options are limited. The aim of this trial was to determine the potential efficacy of transcutaneous electrical acupoint stimulation (TEAS), against dizziness and its safety in patients undergoing MVD.</p></div><div><h3>Methods</h3><p>Adult patients scheduled to undergo MVD for hemifacial spasm under total intravenous anesthesia were randomized at a 1:1 ratio to receive, after extubation, 30-min TEAS in the mastoid region as well as Fengchi acupoints (GB20) and Neiguan acupoints (PC6) or 30-min sham stimulation. The primary outcome was the incidence of dizziness at 2 h after surgery. Secondary outcomes included dizziness, postoperative nausea and vomiting (PONV) or headache severity, rescue medication, changes in intraocular pressure before and after surgery, length of stay, dizziness symptoms 4 weeks after discharge, and surgical complications.</p></div><div><h3>Results</h3><p>A total of 86 patients (51.9 ± 9.4 years of age; 67 women) were enrolled. One patient (in the TEAS arm) was excluded from analysis due to conversion to sevoflurane anesthesia. The rate of dizziness at 2 h after surgery was 31.0 % (13/42) in the TEAS arm <em>vs.</em> 53.5 % (23/43) in the sham control arm (<em>P</em> = 0.036). TEAS was also associated with significantly lower severity of dizziness, based on a 10-point scale, during the first 24 h after surgery. None of the other secondary efficacy outcomes differed significantly between the two arms. All postoperative complications were Clavien-Dindo grade I or II. The rate of postoperative complications was 21.4 % (9/42) in the TEAS arm <em>vs.</em> 16.3 % (7/43) in the sham control arm (<em>P</em> = 0.544).</p></div><div><h3>Conclusions</h3><p>Compared with sham control, TEAS was associated with a lower incidence of dizziness within 2 h and lower severity of dizziness within 24 h post-operatively, but no improvement in other outcomes, in adult patients undergoing MVD for hemifacial spasm.</p></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"83 ","pages":"Article 103055"},"PeriodicalIF":3.6,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0965229924000438/pdfft?md5=cb473f096b37cf611f0111ba772a74f8&pid=1-s2.0-S0965229924000438-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141086893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Huaixing Cui , Naijin Zhang , JiaLi An , Xianyue Zeng , Ye Zhao , Xuan Sun , Huaien Bu , Hongwu Wang
{"title":"Maternal folic acid supplementation to prevent preeclampsia: a systematic review and meta-analysis","authors":"Huaixing Cui , Naijin Zhang , JiaLi An , Xianyue Zeng , Ye Zhao , Xuan Sun , Huaien Bu , Hongwu Wang","doi":"10.1016/j.ctim.2024.103052","DOIUrl":"10.1016/j.ctim.2024.103052","url":null,"abstract":"<div><h3>Objective</h3><p>The purpose of this systematic review was to examine the association between folic acid supplementation during pregnancy and the risk of preeclampsia.</p></div><div><h3>Methods</h3><p>Relevant studies were included by searching Embase, PubMed, Scope, Web of science, Cochrane Library databases. Studies were reviewed according to prespecified inclusion and exclusion criteria. Study characteristics were summarized, and study quality was assessed. Risk ratios (RR) and 95<!--> <!-->% confidence intervals (CI) were used as indicators of effect to assess the relationship between folic acid supplementation and risk of preeclampsia.</p></div><div><h3>Results</h3><p>The protocol of this study was prospectively registered with the PROSPERO (registration No. CRD42022380636). A total of nine studies were included, divided into three groups according to the type of study, containing a total of 107 051 and 105 222 women who were supplemented and not supplemented with folic acid during pregnancy. The results showed that folic acid supplementation during pregnancy could not be proven to reduce the risk of preeclampsia.</p></div><div><h3>Conclusion</h3><p>The results of the study suggest that folic acid supplementation alone is not associated with a decreased risk of pre-eclampsia,but the inferences are somewhat limited by the low methodological quality of the included literature, and therefore higher quality studies are needed to prove this point.</p></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"82 ","pages":"Article 103052"},"PeriodicalIF":3.6,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0965229924000402/pdfft?md5=c558a71e2b030f4264033a15a9acd949&pid=1-s2.0-S0965229924000402-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141049452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Acupuncture for functional dyspepsia: Bayesian meta-analysis","authors":"Xiaoyun Liao , Yu Tian , Yajun Zhang , Zhiyuan Bian , Pingzhu Wang , Peiqi Li , Jianqiao Fang , Xiaomei Shao","doi":"10.1016/j.ctim.2024.103051","DOIUrl":"10.1016/j.ctim.2024.103051","url":null,"abstract":"<div><h3>Background</h3><p>Acupuncture stands out as a prominent complementary and alternative medicine therapy employed for functional dyspepsia (FD). We conducted a Bayesian meta-analysis to ascertain both the relative effectiveness and safety of various acupuncture methods in the treatment of functional dyspepsia.</p></div><div><h3>Methods</h3><p>We systematically searched eight electronic databases, spanning from their inception to April 2023. The eligibility criteria included randomized controlled trials investigating acupuncture treatments for FD. Study appraisal was conducted using the Cochrane risk of bias tool. Pairwise and network meta-analyses were conducted using RevMan 5.3 and ADDIS V.1.16.6 software. Bayesian network meta-analysis was performed to compare and rank the efficacy of different acupuncture therapies for FD symptoms.</p></div><div><h3>Results</h3><p>This study found that combining different acupuncture methods or using acupuncture in conjunction with Western medicine is more effective in improving symptoms of functional dyspepsia compared to using Western medicine alone. According to the comprehensive analysis results, notably, the combination of Western medicine and acupuncture exhibited superior efficacy in alleviating early satiation and postprandial fullness symptoms. For ameliorating epigastric pain, acupuncture combined with moxibustion proved to be the most effective treatment, while moxibustion emerged as the optimal choice for addressing burning sensations. Warming needle was identified as the preferred method for promoting motilin levels.</p></div><div><h3>Conclusion</h3><p>The findings of this study demonstrate that acupuncture, both independently and in conjunction with other modalities, emerged as a secure and effective treatment option for patients with functional dyspepsia.</p></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"82 ","pages":"Article 103051"},"PeriodicalIF":3.6,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0965229924000396/pdfft?md5=53b6403007cccbb308c3731c722995bd&pid=1-s2.0-S0965229924000396-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140956572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}