Complementary therapies in medicine最新文献

{"title":"Effect of aromatherapy with peppermint, ginger, and lavender on postoperative nausea severity after oral surgery under general anaesthesia: A single-blind randomized controlled trial","authors":"Emi Ishikawa,&nbsp;Toshiaki Fujisawa,&nbsp;Yukifumi Kimura,&nbsp;Takayuki Hojo,&nbsp;Nobuhito Kamekura,&nbsp;Kanta Kido","doi":"10.1016/j.ctim.2025.103169","DOIUrl":"10.1016/j.ctim.2025.103169","url":null,"abstract":"<div><h3>Objectives</h3><div>This study aimed to examine whether aromatherapy with peppermint (Mentha piperita Mitcham), ginger (Zingiber officinale), and lavender (Lavandula angustifolia) reduces the severity of nausea in patients experiencing postoperative nausea after oral surgery under general anaesthesia.</div></div><div><h3>Design</h3><div>Single-centre, stratified (volatile inhaled anaesthetics used or not and sex, with balanced randomization), single-blind, placebo-controlled study conducted in Japan.</div></div><div><h3>Setting</h3><div>Hokkaido University Hospital.</div></div><div><h3>Interventions</h3><div>Totally, 182 patients were randomized into two groups of aromatherapy: aroma group comprising three essential oils—peppermint, ginger, and lavender—each diluted to 1 % (each dose as pure essential oil was 0.01 ml) and control group with purified water only. Of these, 32 patients in the aroma group and 25 in the control group complained of postoperative nausea and were treated with intervention.</div></div><div><h3>Main outcome measures</h3><div>Change in nausea severity at the onset of postoperative nausea.</div></div><div><h3>Results</h3><div>Nausea severity before the intervention did not differ between groups. Aromatherapy significantly reduced nausea severity (<em>p</em> &lt; 0.001). The percentages of antiemetics used were 30.77 % and 52.38 % in the aroma and control groups, respectively, with no significant difference. The aroma group showed significantly higher satisfaction (<em>p</em> &lt; 0.001). No adverse events were observed during the study.</div></div><div><h3>Conclusions</h3><div>This study indicated that aromatherapy with peppermint, ginger, and lavender significantly improved patient satisfaction and severity of postoperative nausea after oral surgery under general anaesthesia. Therefore, given the benefits of aromatherapy, it would be advantageous to consider a combination of measures that include aromatherapy, as one of the multimodal antiemetic measures.</div><div>This trial was registered at the Japan Registry of Clinical Trials (jRCTs: 01121002).</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"90 ","pages":"Article 103169"},"PeriodicalIF":3.3,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143714328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interventions used in control group against cupping therapy for chronic nonspecific low back pain: A systematic review and network meta-analysis","authors":"Junyan Li ,&nbsp;Yuanyuan Jia ,&nbsp;Tingting Sun ,&nbsp;Zhenmin Bai ,&nbsp;Xiaosheng Dong ,&nbsp;Xiao Hou","doi":"10.1016/j.ctim.2025.103167","DOIUrl":"10.1016/j.ctim.2025.103167","url":null,"abstract":"<div><h3>Introduction</h3><div>The evidence for the effect of cupping therapy on chronic nonspecific low back pain (CLBP) remains controversial, and existing researches didn’t consider outcomes influenced by factor of selection of interventions in control group. This review and network meta-analysis is to compare the effects of diverse interventions in cupping therapy control groups for CLBP, with the objective of identifying the suitable control intervention against cupping therapy for CLBP.</div></div><div><h3>Methods</h3><div>Studies were identified by a comprehensive search of databases, such as PubMed, Embase, Cochrane Library, Web of Science and China National Knowledge Infrastructure (CNKI), up to June, 2024. A total of 10 randomized control trials (RCT) were included in this network meta-analysis (NMA).</div></div><div><h3>Results</h3><div>The results showed that compared with cupping therapy, minimum negative pressure cupping therapy (MNPCT) (SMD = − 0.01; 95 %CI: − 0.92 to 0.89), air circulating cupping therapy (ACCT) (SMD = − 0.05; 95 %CI: − 0.63 to 0.54) and diclofenac (SMD = − 0.13; 95 %CI: − 1.13 to − 0.87) was no significantly different from improvement of pain intensity. But there was significant difference between cupping therapy and D-ibuprofen (SMD = − 1.11; 95 %CI: − 2.08 to − 0.13), paracetamol (SMD = − 1.12; 95 %CI: − 1.80 to − 0.43) or usual care (SMD = − 1.18; 95 %CI: − 2.56 to − 1.06). The order of intervention effect by SUCRA diagram was as follows: cupping therapy (77.7 %) &gt; MNPCT (75.2 %) &gt; ACCT (73.8 %) &gt; diclofenac (68.8 %) &gt; D-ibuprofen (26.3 %) &gt; paracetamol (24.5 %) &gt; usual care (3.8 %). The quality of evidence for network estimates was moderate to very low due to the risk of bias and imprecision.</div></div><div><h3>Conclusions</h3><div>The results of this study suggest that usual care was the least effective in alleviating the pain intensity of CLBP, which might serve as the most appropriate intervention in the control group in cupping-related RCTs. MNPCT and ACCT have similar effects with cupping therapy for CLBP. Future research may be based on some objective clinical outcomes and control interventions with physiological inertia to isolate the true effect of cupping therapy or SCT from psychological biases.</div></div><div><h3>Trial registration</h3><div>The protocol was registered on the international prospective register of systematic reviews (<span><span>http://www.crd.york.ac.uk/PROSPERO</span><svg><path></path></svg></span>), registration number: CRD42024527513.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"90 ","pages":"Article 103167"},"PeriodicalIF":3.3,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143699848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pharmacokinetic interactions of fruit juices with antihypertensive drugs in humans: A systematic review and meta-analysis","authors":"Janthima Methaneethorn ,&nbsp;Piyameth Dilokthornsakul ,&nbsp;Tippawan Siritientong ,&nbsp;Zheng Jiao ,&nbsp;Wanaporn Chareonchokthavee ,&nbsp;Nattawut Leelakanok","doi":"10.1016/j.ctim.2025.103165","DOIUrl":"10.1016/j.ctim.2025.103165","url":null,"abstract":"<div><h3>Introduction</h3><div>Fruit juice-antihypertensive drug interactions can lead to subtherapeutic or supratherapeutic outcomes. This systematic review and meta-analysis assesses such interactions and their potential clinical relevance.</div></div><div><h3>Methods</h3><div>PubMed, Scopus, and Science Direct databases were searched from their inception through June 2024. Eligible studies were those that investigated the effects of fruit juice on the pharmacokinetics of antihypertensive drugs. <em>I</em>^<em>2</em> was used to determine heterogeneity among studies, and a random effect model was employed for meta-analysis. This review adhered to PRISMA guidelines and was registered in PROSPERO (CRD42022340159).</div></div><div><h3>Results</h3><div>Fifty-one studies were included. Most of them were open-label crossover trials. Grapefruit juice (GFJ), an inhibitor of organic-anion-transporting polypeptide (OATP) transporters and cytochrome P450 (CYP) 3A4, significantly decreased the AUC and C_max of aliskiren and celiprolol by approximately 80–90 %. Conversely, the AUC and C_max of calcium channel blockers decreased with variable degrees when co-administered with GFJ. Apple and orange juices have comparable effects on certain medications. Most studies had small sample sizes and were of moderate quality. Hemodynamic effects were not assessed in most studies; thus, the clinical significance of these interactions remains uncertain and should be further investigated.</div></div><div><h3>Conclusion</h3><div>Co-administration of fruit juice with antihypertensive drugs can result in an increase or decrease in drugs’ bioavailability, depending on the drugs’ metabolism route and the involvement of transporters. Though further studies are needed to confirm clinical relevance in hypertensive patients, it is advised to avoid co-consumption of fruit juice with drugs showing significant changes in pharmacokinetic parameters to prevent subtherapeutic or supratherapeutic effects.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"90 ","pages":"Article 103165"},"PeriodicalIF":3.3,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143691373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is integrating acupuncture into the management of attention-deficit/hyperactivity disorder among children and adolescents now opportune and evidence-based? A systematic review with meta-analysis and trial sequential analysis","authors":"Fei-Yi Zhao ,&nbsp;Yan Xu ,&nbsp;Gerard A. Kennedy ,&nbsp;Russell Conduit ,&nbsp;Wen-Jing Zhang ,&nbsp;Ting Jiang ,&nbsp;Peijie Xu ,&nbsp;Yuen-Shan Ho ,&nbsp;Qiang-Qiang Fu ,&nbsp;Chin-Moi Chow","doi":"10.1016/j.ctim.2025.103163","DOIUrl":"10.1016/j.ctim.2025.103163","url":null,"abstract":"<div><h3>Background and aim</h3><div>The use of acupuncture is becoming increasingly popular in the management of attention-deficit/hyperactivity disorder (ADHD). This systematic review consolidates evidence on acupuncture’s efficacy and safety for treating ADHD in children and adolescents.</div></div><div><h3>Methods</h3><div>Controlled clinical trials assessing acupuncture against waitlist-control, placebo or active controls, or as an adjunct treatment were systematically searched across seven databases from inception to November 2024. Cochrane criteria were adhered to.</div></div><div><h3>Results</h3><div>We reviewed 25 studies with 1758 participants. None compared acupuncture to placebo or behavioral therapy. Subdomain analysis of the Conners’ Parent Rating Scale indicated that acupuncture and Methylphenidate had comparable effects on <em>Conduct Problems</em> [<em>SMD</em> = 0.03, 95 %<em>CI</em> (-0.93, 0.99), <em>p</em> = 0.95] and <em>Learning Problems</em> [<em>SMD</em> = 0.29, 95 %<em>CI</em> (-0.38, 0.97), <em>p</em> = 0.39], but acupuncture was more effective in controlling <em>Impulsive/Hyperactive</em> symptoms [<em>SMD</em> = -1.71, 95 %<em>CI</em> (-2.08, −1.35), <em>p</em> &lt; 0.01]. Insufficient sample size prevented confirmation of potential false positives. Acupuncture was safer and reduced Methylphenidate-related side-effects, including appetite loss, sleep disturbances, dry mouth, abdominal pain, and constipation. Acupuncture combined with behavioral therapy outperformed behavioral therapy alone in improving <em>Psychosomatic</em> symptoms [<em>SMD</em> = -0.88, 95 %<em>CI</em> (-1.54, −0.23), <em>p</em> &lt; 0.01]. In the Integrated Visual and Auditory Continuous Performance Test, ADHD patients receiving acupuncture alongside conventional care performed better than those receiving conventional care alone. Nevertheless, the methodological quality of the included trials was very low to low, with significant bias risk, and 88 % lacked follow-up.</div></div><div><h3>Conclusions</h3><div>Acupuncture may offer an alternative for children and adolescents with ADHD who are intolerant to medication (primarily Methylphenidate). When combined with medication or behavioral therapy, it appeared more effective in ameliorating hyperactivity/impulsivity, inattention and conduct problems than standard treatments alone. It is also safe and well-tolerated. However, the supporting evidence is of low quality, and well-designed randomized controlled trials are needed. Thus, it is premature to recommend acupuncture as an alternative or adjunctive therapy for ADHD management.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"90 ","pages":"Article 103163"},"PeriodicalIF":3.3,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Motor learning-based clinical pilates training for the Parkinson’s disease rehabilitation @Parkinsonpilates: A parallel group, randomised controlled trial with 3-month follow-up","authors":"Fahriye Coban ,&nbsp;Beliz Belgen Kaygisiz ,&nbsp;Ferda Selcuk","doi":"10.1016/j.ctim.2025.103161","DOIUrl":"10.1016/j.ctim.2025.103161","url":null,"abstract":"<div><h3>Objectives</h3><div>To examine the effect of integrated motor learning clinical pilates protocol we developed for patients with Parkinson’s Disease (pwPD) on providing enduring motor skills in walking, balance, reaction time, cadence, and functional mobility at 3-months follow-up.</div></div><div><h3>Design</h3><div>A parallel-group, randomized controlled trial (RCT).</div></div><div><h3>Setting</h3><div>XXX Medical Center, XXX, and XXX Physiotherapy and Rehabilitation Center, Nicosia.</div></div><div><h3>Participants</h3><div>32 pwPD with Hoehn&amp;Yahr stages 2–3 were randomly assigned to the Parkinsonpilates Group (PP) and the Conventional Physiotherapy (CP) Group.</div></div><div><h3>Interventions</h3><div>Both groups received 60 min of training, twice a week, and a home physiotherapy program 4 times a week, for 12 weeks. The intervention group received PP, while the CP group received general physiotherapy training for PD.</div></div><div><h3>Main outcome measures</h3><div>The primary outcomes were untimed Gait and Balance Scale, Cadence, and Nelson Foot Reaction Test scores. The secondary outcomes were The Unified Parkinson's Disease Rating Scale-III subscales, Timed Up and Go Test, Functional Reach Test, and Berg Balance Scale. Outcomes were convened 4 times: pre-test, 6. weeks, post-treatment, and after 3-month follow-up.</div></div><div><h3>Results</h3><div>At post-test, gait and balance, reaction time, functional mobility, static and dynamic balance showed a significant improvement in PP compared to CP, and the motor examination was similar(p &gt; .05). In addition to these results at follow-up, functional mobility was similar(p &gt; .05) and cadence(p &lt; .05) showed a significant improvement in PP. In addition, according to pairwise comparisons, the PP showed a significant improvement in cadence and reaction time in all 4 measures compared to CP.</div></div><div><h3>Conclusions</h3><div>More studies are needed to clarify the effects of the program we developed for PD. It should not be ignored that our protocol can be improved again according to the suggestions of future studies.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"90 ","pages":"Article 103161"},"PeriodicalIF":3.3,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143591771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness and safety of acupoint embedding therapy for treating intractable facial paralysis: A systematic review and meta-analysis","authors":"Xiaotong Guo ,&nbsp;Fenglei Zai ,&nbsp;Xianliang Tang ,&nbsp;Yongkang Deng ,&nbsp;Jianghui Cheng","doi":"10.1016/j.ctim.2025.103162","DOIUrl":"10.1016/j.ctim.2025.103162","url":null,"abstract":"<div><h3>Objective</h3><div>Limited systematic reviews have explored the impact of acupoint embedding (AE) therapy on intractable facial paralysis (IFP). This review presents the current evidence on the efficacy and safety of AE therapy in the treatment of IFP.</div></div><div><h3>Methods</h3><div>PubMed, Embase, Cochrane Library, Web of Science, Chinese Biomedical Literature Database, VIP Database for Chinese Technical Periodicals, China National Knowledge Infrastructure, and Wanfang databases were systematically searched from inception to February 2024 to identify randomized controlled trials (RCTs) without language restrictions. Data extraction and analysis were independently conducted by two reviewers. The Risk of Bias was assessed using the Risk of Bias tool (version 2.0), and a meta-analysis was performed using the RevMan software (V5.4).</div></div><div><h3>Setting</h3><div>Eighteen RCTs involving 1881 patients were included in the analysis.</div></div><div><h3>Results</h3><div>AE therapy demonstrated a higher total effective rate (relative risk [RR]: 1.28; 95 % confidence interval [CI]: 1.13–1.44; P &lt; 0.0001), cure rate (RR: 1.81; 95 % CI: 1.05–3.12; P = 0.03), and facial nerve function score (standardized mean differences [SMD]: 1.57; 95 % CI: 1.16–1.99; P &lt; 0.00001) compared to that of manual acupuncture. Additionally, AE therapy showed a higher total effective rate (RR: 1.16; 95 % CI: 1.10–1.22; P &lt; 0.00001) and cure rate (RR: 1.70; 95 % CI: 1.46–1.98; P &lt; 0.00001) in comparison to that of electroacupuncture. However, there were no significant differences in facial nerve function scores(SMD:2.04; 95 % CI: −1.25–5.32; P = 0.22) or adverse reactions(RR: 1.16; 95 % CI: 0.35–3.78; P = 0.81) between AE therapy and electroacupuncture therapy. Evidence supporting the efficacy and safety of AE treatment is also insufficient.</div></div><div><h3>Conclusion</h3><div>Most of the included studies indicated that AE therapy was more effective than MA/EA therapy for IFP. However, the quality of evidence for the majority of these studies was low, and all were conducted in China, where limited information has been reported regarding the safety of AE therapy.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"90 ","pages":"Article 103162"},"PeriodicalIF":3.3,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alternative therapies in chronic non-cancer pain management: A scoping review of randomized controlled trials","authors":"Yuxing Zhang ,&nbsp;Bangqi Wu ,&nbsp;Peng Qin ,&nbsp;Yupei Cheng ,&nbsp;Yuyan Chen","doi":"10.1016/j.ctim.2025.103154","DOIUrl":"10.1016/j.ctim.2025.103154","url":null,"abstract":"<div><h3>Background</h3><div>Chronic pain is one of the most challenging health problems in modern society, placing significant burdens on individuals and healthcare systems. While pharmacological treatments remain the primary approach to pain management, their limitations often restrict choices for both clinicians and patients. In contrast, complementary therapies are gaining recognition for their potential effectiveness and safety. However, the current literature lacks a comprehensive summary of the role of complementary therapies in chronic pain management.</div></div><div><h3>Objective</h3><div>This review aims to summarize the complementary therapies used in chronic non-cancer pain management, assess their practical applications, identify research gaps and limitations, and provide a comprehensive perspective for the development of chronic non-cancer pain management and personalized pain management strategies.</div></div><div><h3>Methods</h3><div>This scoping review followed the PRISMA-ScR guidelines. Randomized controlled trials (RCTs) published in the last decade were retrieved from PubMed and Web of Science using the keywords \"chronic pain\" and \"complementary therapy.\" Non-English studies were excluded.</div></div><div><h3>Results</h3><div>A total of 848 RCTs were identified, of which 128 met the inclusion criteria. The included studies addressed chronic musculoskeletal pain (102 studies), chronic visceral pain (5 studies), chronic neuropathic pain (7 studies), and 13 studies that did not specify the pain type. The complementary therapies investigated included acupuncture, manual therapy, exercise therapy, psychological interventions, mind-body therapies, and physical modalities.</div></div><div><h3>Conclusion</h3><div>This review provides preliminary evidence supporting the efficacy and safety of complementary therapies in the management of chronic non-cancer pain. However, methodological and quality-related limitations were identified in the included studies. Future high-quality RCTs are needed to validate the long-term efficacy of these therapies, explore their mechanisms of action, and provide stronger evidence for their clinical application.</div></div><div><h3>Registration</h3><div>This scoping review is registered on the Open Science Framework (OSF) under the following DOI: <span><span>https://doi.org/10.17605/OSF.IO/67K32</span><svg><path></path></svg></span>.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"90 ","pages":"Article 103154"},"PeriodicalIF":3.3,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143609991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of biofeedback for migraine: A systematic review and meta-analysis","authors":"Prayash Paudel,&nbsp;Asutosh Sah","doi":"10.1016/j.ctim.2025.103153","DOIUrl":"10.1016/j.ctim.2025.103153","url":null,"abstract":"<div><div>Migraine, a severe headache accompanied by nausea, photophobia and phonophobia, can be controlled with pharmacological as well as non-pharmacological therapies. In biofeedback, patients learn to voluntarily modify their bodily reactions through feedback mediated awareness of physiological parameters, thus promoting relaxation, reducing stress and preventing migraine attacks. We aim to assess the efficacy of biofeedback on adult patients with migraine. Study protocol was registered on PROSPERO with reference number CRD42024606671. PubMed, Embase and Google Scholar were searched for randomized controlled trials from 2000 to 2024 in English that have evaluated the administration of biofeedback to the adult patients with migraine. High quality studies were included after RoB 2.0 Risk of Bias assessment. ANOVA with inverse variance weighting was used to compare mean differences across groups with 95 % confidence interval. Nine studies (558 participants) and three studies (278 participants) respectively qualified for comparison of biofeedback with waiting list control and active treatment. Biofeedback significantly reduced headache frequency and severity compared to waiting-list control. However, it showed no significant difference in headache frequency when compared to active treatments such as pharmacotherapy or cognitive behavioral therapy. Additionally, improvements in migraine-related disability, depression, anxiety, and quality of life were reviewed. This meta-analysis confirms that biofeedback is an effective non-pharmacological intervention for reducing headache frequency and severity in migraines. Additionally, it appears to provide synergistic benefits when combined with pharmacotherapy. However, future studies should focus on the cost-effectiveness and accessibility of home-based and app-based biofeedback to determine its broader clinical applicability.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"90 ","pages":"Article 103153"},"PeriodicalIF":3.3,"publicationDate":"2025-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143596425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Mawangdui exercise intervention on the pulmonary function, physical fitness and quality of life in stable chronic obstructive pulmonary disease patients: A randomised controlled trial","authors":"Zhenggang Zhu ,&nbsp;Ayu Suzailiana Muhamad ,&nbsp;Norsuhana Omar ,&nbsp;Foong Kiew Ooi ,&nbsp;Xiaoyan Pan ,&nbsp;Marilyn Li Yin Ong","doi":"10.1016/j.ctim.2025.103152","DOIUrl":"10.1016/j.ctim.2025.103152","url":null,"abstract":"<div><h3>Background</h3><div>Physical exercise intervention in pulmonary rehabilitation is recommended to increase strength, endurance, and flexibility in chronic obstructive pulmonary disease (COPD). However, certain physical intervention may be restrictive to COPD patients, as it induces fatigue and shortness of breath. Mawangdui exercise, a low-to-medium-intensity aerobic exercise, has been gaining popularity in China as an adjuvant physical therapy, particularly for patients with contraindications to exercise, to improve their health.</div></div><div><h3>Objective</h3><div>To investigate the effectiveness of the traditional Chinese Mawangdui exercise for patients with COPD in a mild to moderate stable stage.</div></div><div><h3>Methods</h3><div>A total of 54 COPD patients in stable stage (Mawangdui group, n = 27; control group, n = 27) were enroled for a period of 12-weeks. The Mawangdui group practised the Mawangdui exercise, while the control group maintained daily activities without additional exercise. The outcomes measurements were pulmonary function, exercise capacity, back-leg-chest muscle strength, sit-and-reach flexibility, dyspnoea symptoms, and quality of life. The outcomes were assessed at baseline, 24 h, 6 weeks, and 12 weeks post-intervention.</div></div><div><h3>Results</h3><div>Improvements were observed for Borg CR-10 score, SpO₂, BMI, body fat%, fat mass, flexibility mMRC, and SGRQ scores (<em>p</em> &lt; 0.05) at 12 weeks. At week 12, Mawangdui group showed improved exercise capacity (6MWT mean difference 63.39 m, CI 48.36－78.40), back-leg-chest muscle strength (mean difference 5.92 kg, CI −2.57－-14.41), and dyspnoea (CAT score mean difference −5.50, CI −6.42－-4.59) in per-protocol population. However, FEV₁, FVC, FEV₁% pred, and fat-free mass did not show improvements with Mawangdui exercise.</div></div><div><h3>Conclusion</h3><div>COPD patients in stable stage who performed Mawangdui exercise for 12 weeks improved exercise capacity, dyspnoea, muscle strength, flexibility, BMI, body fat%, fat mass and quality of life. Therefore, Mawangdui exercise is recommended for COPD patients in the stable stage to improve physical fitness and quality of life.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"89 ","pages":"Article 103152"},"PeriodicalIF":3.3,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143540426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of music intervention on dental anxiety and fear: A bibliometric analysis of RCTs from 2004 to 2024","authors":"Yena Gan ,&nbsp;Jinwei Huang ,&nbsp;Sheng Han ,&nbsp;He Xu ,&nbsp;He Zhu ,&nbsp;Duoduo Li ,&nbsp;Zening Wei ,&nbsp;Feng Sun ,&nbsp;Zhigang Cai","doi":"10.1016/j.ctim.2025.103148","DOIUrl":"10.1016/j.ctim.2025.103148","url":null,"abstract":"<div><h3>Background</h3><div>Dental treatments, especially invasive procedures, often induce anxiety and fear, impacting future treatment adherence. Music intervention, a non-pharmacological approach, has shown promise in reducing anxiety and enhancing well-being, but further research is needed to explore its application in dental settings and the influence of factors like music type, duration, and volume.</div></div><div><h3>Objective</h3><div>To assess the effects of music interventions on dental anxiety and fear, analyze research trends, and identify knowledge gaps through a bibliometric analysis of randomized controlled trials.</div></div><div><h3>Methods</h3><div>Data from eligible studies were extracted through a comprehensive search. Descriptive bibliometrics, citation analysis, and keyword analysis were performed to assess research outputs, distribution, hotspots, and trends. Different human development indices (HDI) were used to analyze variations in publication year, sex distribution, and interventions across countries.</div></div><div><h3>Results</h3><div>This study included 46 randomized controlled trials (RCTs) from 2004 to 2024, with a mean annual growth rate of 5.95 %. India, Japan, and Turkey led the research output and citations. Approximately 4112 participants, with 45.68 % males were enrolled. Most RCTs focused on adults (65.22 %) and used passive music interventions (73.91 %). The most common treatment was dental extraction (39.13 %), with classical music being the predominant intervention (60.87 %). The control group were often blank (80.43 %). Various indicators of anxiety and fear have been reported. Significant differences were found in the sex distribution among the different HDI ranks (p &lt; 0.001).</div></div><div><h3>Conclusions</h3><div>This study outlined the research profile of music interventions for reducing anxiety and fear during dental treatments, with India, Japan, and Turkey leading in terms of output. The most frequently studied intervention is classical music, which is typically used preoperatively. Notable sex distribution differences were observed across HDI groups. Future research trends should include more extensive trials, personalized interventions, standardized guidelines, and enhanced collaboration to optimize patient engagement and emotional regulation.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"89 ","pages":"Article 103148"},"PeriodicalIF":3.3,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143519750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}