{"title":"Efficacy of Hibiscus sabdariffa L. extract on metabolic parameters in participants with abdominal obesity and mild metabolic syndrome in Bangkok, Thailand: A double-blind, randomized, placebo-controlled trial","authors":"Kanchaporn Chaisungnern , Thanapoom Rattananupong , Rossukon Klinhom , Srisuphak Nanta , Kamonwan Banchuen , Arunporn Itharat , Pranporn Kuropakornpong , Thanan Supasiri , Preecha Nootim , Wiroj Jiamjarasrangsi","doi":"10.1016/j.ctim.2025.103185","DOIUrl":"10.1016/j.ctim.2025.103185","url":null,"abstract":"<div><h3>Background</h3><div><em>Hibiscus sabdariffa</em> L. (HS) has been investigated as an alternative treatment for metabolic syndrome (MetS), as it affects all MetS components with low side effects simultaneously; however, clinical evidence regarding its efficacy compared with placebo is inconsistent. This study assessed how the aqueous calyx extract of HS influences insulin resistance and MetS parameters and examined the safety effects on liver, kidney, and hematological indexes in participants with abdominal obesity and mild MetS symptoms.</div></div><div><h3>Methods</h3><div>In this double-blind, randomized, placebo-controlled trial, 108 participants with MetS were randomly assigned to take 1000-mg HS (45.04 mg/day in total polyphenols) or placebo daily for 12 weeks. Insulin resistance (HOMA-IR), glycemic markers, body mass index (BMI), waist circumference (WC), lipid profiles, and blood pressure were assessed at baseline, 6 weeks, and 12 weeks. Additionally, liver and kidney function indicators along with hematological parameters were evaluated.</div></div><div><h3>Results</h3><div>Compared with placebo, HS did not significantly affect HOMA-IR, glycemic markers, BMI, WC, lipid profile, or blood pressure. Although HS did not significantly alter the lipid profile overall, serum low-density lipoprotein (LDL) levels decreased significantly at 12 weeks compared with baseline (− 7.98 mg/dL, [95 % CI, − 14.80, − 1.15]). Additionally, HS did not cause significant liver or kidney function or hematological changes compared with placebo.</div></div><div><h3>Conclusion</h3><div>Taking 1000-mg HS daily for 12 weeks seems to be safe. Placebo and HS groups showed good clinical results, and the extract was not associated with improved metabolic parameters in individuals with abdominal obesity and mild MetS symptoms, with the exception of lower serum LDL.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"91 ","pages":"Article 103185"},"PeriodicalIF":3.3,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143946532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tong Li , Gerhard Litscher , Yudian Zhou , Yanjuan Song , Qing Shu , Li Chen , Qi Huang , Yayuan Wang , Haoran Tian , Rufeng Teng , Hua Wang , Fengxia Liang
{"title":"Effects of acupuncture and moxibustion on heart rate variability in chronic fatigue syndrome patients: Regulating the autonomic nervous system in a clinical randomized controlled trial","authors":"Tong Li , Gerhard Litscher , Yudian Zhou , Yanjuan Song , Qing Shu , Li Chen , Qi Huang , Yayuan Wang , Haoran Tian , Rufeng Teng , Hua Wang , Fengxia Liang","doi":"10.1016/j.ctim.2025.103184","DOIUrl":"10.1016/j.ctim.2025.103184","url":null,"abstract":"<div><h3>Background</h3><div>This study investigates the effects of various acupuncture techniques, specific acupuncture points, and their combinations on symptom improvement in chronic fatigue syndrome (CFS) patients as well as their influence on heart rate variability (HRV) indicators.</div></div><div><h3>Methods</h3><div>We recruited 35 healthy subjects as a healthy control group (Group A) and 175 patients with CFS, who were randomly divided into a fake acupuncture group (Group B), an acupuncture group targeting the Zusanli (ST36) point (Group C), an acupuncture group targeting the Guanyuan (CV4) point (Group D), a dual-acupoint acupuncture group (Group E), and a moxibustion group (Group F), with 35 patients in each group. Group B received fake acupuncture at both the bilateral Zusanli and Guanyuan points simultaneously. Group C received acupuncture at the bilateral Zusanli points along with fake acupuncture at the Guanyuan point. Group D received acupuncture at the Guanyuan point along with fake acupuncture at the bilateral Zusanli points. Group E received acupuncture at both the bilateral Zusanli and Guanyuan points simultaneously, and Group F received moxibustion at both the bilateral Zusanli and Guanyuan points simultaneously. Each group received a total of 10 treatments, administered every other day. Before treatment, the Qi-deficiency Syndrome Score, CFS Score, and SF36 Score were assessed for all subjects. HRV was measured before treatment, after the first treatment, after the fourth treatment, and at the end of treatment.</div></div><div><h3>Results</h3><div>The results showed that both acupuncture and moxibustion can effectively alleviate fatigue symptoms in patients suffering from CFS, with combined acupuncture and moxibustion demonstrating greater effectiveness.</div></div><div><h3>Conclusion</h3><div>Acupuncture excelled in regulating the immediate effects of HRV, while moxibustion excelled in regulating long-term effects. Acupuncture targeting both the Zusanli and Guanyuan points proved more effective than acupuncture targeting a single point, with this difference reflected in the distinct regulatory effects on the sympathetic and parasympathetic nervous systems. The intervention mechanism of Zusanli may involve the parasympathetic nervous system, whereas Guanyuan may operate through the sympathetic nervous system.</div></div><div><h3>Trial registration</h3><div>Approved by the Medical Ethics Committee of Hubei Provincial Hospital of Traditional Chinese Medicine (Approval number: HBZY2016-C24-01), and registered with the North American Clinical Trials Data Center (Clinical Trials.gov) (05/10/2016) (registration number: NCT02924831).</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"92 ","pages":"Article 103184"},"PeriodicalIF":3.3,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143966914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to the editor regarding “Transcutaneous electrical acupoint stimulation to prevent dizziness after microvascular decompression for hemifacial spasm: A randomized controlled trial” by Yuantao Hou et al.","authors":"Xinyu Yang , Xinyuan Chen , Xiaowen Guo","doi":"10.1016/j.ctim.2025.103176","DOIUrl":"10.1016/j.ctim.2025.103176","url":null,"abstract":"","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"91 ","pages":"Article 103176"},"PeriodicalIF":3.3,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143882581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Response to letter to the editor on: “The efficacy of oral Lavandula angustifolia Mill. essential oil on menopausal symptoms, serum lipid profile, and cortisol concentration in postmenopausal women: A triple-blind, randomized, controlled trial”","authors":"Soraya Babaie, Morteza Haramshahi, Mahnaz Shahnazi, Behnam Kafil, Azizeh Farshbaf-Khalili , Mina Naghdi","doi":"10.1016/j.ctim.2025.103179","DOIUrl":"10.1016/j.ctim.2025.103179","url":null,"abstract":"","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"91 ","pages":"Article 103179"},"PeriodicalIF":3.3,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143879412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zheng Sun , Haitian Sun , Kuang Yu , Zilong Zhu , Yiren Lin , Ke Sun , Jianbin Zhang
{"title":"A systematic review and meta-analysis of acupuncture's impact on hemiplegic gait recovery after stroke","authors":"Zheng Sun , Haitian Sun , Kuang Yu , Zilong Zhu , Yiren Lin , Ke Sun , Jianbin Zhang","doi":"10.1016/j.ctim.2025.103181","DOIUrl":"10.1016/j.ctim.2025.103181","url":null,"abstract":"<div><h3>Objective</h3><div>This systematic review aims to evaluate the efficacy and safety of acupuncture in alleviating gait disturbances in post-stroke hemiplegia, focusing on various gait parameters.</div></div><div><h3>Methods</h3><div>A comprehensive search was conducted across PubMed, EMBASE, Cochrane Library, Web of Science, AMED, CINAHL, CBM, CNKI, and WanFang databases to identify relevant randomized controlled trials (RCTs). The included studies were independently evaluated for risk of bias using Cochrane's risk of bias tool. RevMan 5.3 was used for meta-analysis, and adverse events were collected through full-text review.</div></div><div><h3>Results</h3><div>A total of 21 RCTs involving 1463 participants were included. Results showed that acupuncture combined with rehabilitation therapy (RT) significantly improved stride and step length (MD = 7.79, 95 % CI: 5.62–9.96, Z = 7.03, P < 0.00001, I² = 72 %), cadence (MD = 10.43, 95 % CI: 6.22–14.65, Z = 4.85, P < 0.00001, I² = 95 %), walking speed (MD = 12.27, 95 % CI: 9.22–15.31, Z = 7.90, P < 0.00001, I² = 91 %), hip peak flexion angle (MD = 2.71, 95 % CI: 0.94–4.49, Z = 2.99, P = 0.003, I² = 82 %), and ankle peak plantarflexion angle (MD = 2.08, 95 % CI: 1.11–3.06, Z = 4.19, P < 0.0001, I² = 0 %) compared to RT alone. It also reduced gait cycle time (MD = −0.61, 95 % CI: −0.96 to −0.26, Z = 3.44, P = 0.0006, I² = 98 %) and the proportion of double support phase (MD = −7.16, 95 % CI: −9.08 to −5.25, Z = 7.33, P < 0.00001, I² = 0 %). These improvements in gait parameters suggest enhanced mobility and functional independence for post-stroke patients. However, heterogeneity in participant characteristics and study methodologies was noted, such as variations in stroke types, curses, severity, and acupuncture protocols. The majority of RCTs exhibited moderate to high risk of bias regarding allocation concealment and blinding. Only two RCTs reported no adverse events, while the rest 19 studies did not mention adverse events.</div></div><div><h3>Conclusion</h3><div>Acupuncture appears to enhance specific aspects of hemiplegic gait, though further high-quality research is needed to fully validate its effects. Current evidence is limited by methodological weaknesses and potential biases in the included studies. Rigorous, well designed studies are needed to further validate the comprehensive effects of acupuncture on post-stroke hemiplegic gait.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"91 ","pages":"Article 103181"},"PeriodicalIF":3.3,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143887055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wei J. Chua , Jing Liu , Kaitlyn Lam , Alison Maunder , Chhiti Pandey , Adele E. Cave , Allana O’Fee , Guoyan Yang , Aya Mousa , Carolyn Ee
{"title":"The effectiveness and safety of integrative medicine for chronic heart failure: An umbrella review","authors":"Wei J. Chua , Jing Liu , Kaitlyn Lam , Alison Maunder , Chhiti Pandey , Adele E. Cave , Allana O’Fee , Guoyan Yang , Aya Mousa , Carolyn Ee","doi":"10.1016/j.ctim.2025.103182","DOIUrl":"10.1016/j.ctim.2025.103182","url":null,"abstract":"<div><h3>Background and purpose</h3><div>Heart failure (HF) is associated with multi-organ dysfunction and significant morbidity and mortality. Despite advances in treatment, prognosis remains poor, highlighting the need to explore adjunctive therapies such as integrative medicine. This umbrella review synthesises top-tier evidence from systematic reviews and meta-analyses of randomised controlled trials (RCTs) assessing the safety and effectiveness of integrative medicine in patients with HF, in order to inform clinical decision-making.</div></div><div><h3>Methods</h3><div>We searched MEDLINE, Cochrane, PsycINFO and EMBASE until April 2024. Primary outcomes included mortality, hospitalisation rates, and severity or prognostic indicators, including brain natriuretic peptide (BNP) and exercise capacity. A hierarchical evidence synthesis method was used whereby we included the most recent, highly ranked and comprehensive reviews for our research question. We assessed review quality using ‘A MeaSurement Tool to Assess systematic Reviews’ and, where possible, evidence certainty for our primary outcomes using the Grading of Recommendations Assessment, Development and Evaluation approach.</div></div><div><h3>Results</h3><div>Twenty-two reviews were included. Co-enzyme Q10 or <em>Tai Chi</em> may reduce mortality and hospitalisation rates (moderate certainty evidence), and acupuncture or intravenous Chinese herbal medicines may improve BNP (low to very low certainty evidence). The benefits of yoga and other nutrient supplements including L-carnitine remain unclear. Vitamin E may increase hospitalisation rates and should be avoided.</div></div><div><h3>Conclusion</h3><div>The evidence for most integrative medicine modalities for adjunctive management of HF remains limited. Well-designed and rigorous RCTs are needed, particularly with long-term follow up and evaluation of clinically meaningful outcomes.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"91 ","pages":"Article 103182"},"PeriodicalIF":3.3,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143892280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cong Liu , Kim Geok Soh , Su Peng Loh , He Sun , Kim Lam Soh , Yujin Ma , Hucheng Ma
{"title":"Effects of health qigong on cervical spondylosis: A systematic review","authors":"Cong Liu , Kim Geok Soh , Su Peng Loh , He Sun , Kim Lam Soh , Yujin Ma , Hucheng Ma","doi":"10.1016/j.ctim.2025.103180","DOIUrl":"10.1016/j.ctim.2025.103180","url":null,"abstract":"<div><h3>Aim</h3><div>Exercise therapy is a widely utilized intervention for the prevention and rehabilitation of cervical spondylosis. As a distinctive form of traditional exercise therapy in China, Health Qigong has been empirically validated to exert beneficial effects across 17 physiological systems, with particularly pronounced efficacy in addressing musculoskeletal disorders. This systematic review aims to critically evaluate the impact of Health Qigong on cervical spondylosis.</div></div><div><h3>Methods</h3><div>According to the literature search principles, works published from the publication date to November 2024 were searched. The databases used were the China National Knowledge Infrastructure, Scopus, PubMed, Web of Science, and EBSCOhost (SPORTDiscus). The study quality was evaluated using the Physiotherapy Evidence Database (PEDro) scale. The search process was documented using the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA)2020.</div></div><div><h3>Results</h3><div>A total of 10 studies were selected from an initial pool of 702 studies, comprising 656 participants. The PEDro scores of the 10 studies ranged from seven to eight. The findings indicate that Health Qigong exerts its therapeutic effects on cervical spondylosis primarily in four key areas: alleviating neck pain, improving cervical dysfunction, restoring cervical curvature, and enhancing cervical mobility. Specifically, for pain relief, the Visual Analog Scale(VAS) scores showed a mean reduction of 2.8–4.15 points, while the Neck Disability Index (NDI) scores significantly decreased from 6.10 to 1.4. And after intervention, the prevalence of abnormal cervical curvature decreased by 10.97 %, cervical range of motion (CROM) improved by 19.78° to 67.4° on average. Furthermore, according to the Traditional Chinese Medicine (TCM) Diagnostic and Treatment Criteria, five studies reported an overall effectiveness rate exceeding 90 %, with a maximum of 97.14 %. Short-term intervention outcomes indicated that Ba Duan Jin showed a recurrence rate of 0 %, whereas interventions using Yi Jin Jing and Wu Qin Xi exhibited recurrence rates ranging from 11.2 % to 13.33 %.</div></div><div><h3>Conclusion</h3><div>As an exercise-based intervention, Health Qigong not only helps alleviate cervical spondylosis-related pain and improve cervical dysfunction but also promotes the restoration of cervical curvature and enhances cervical mobility, thereby addressing limitations in neck function. However, current research exhibits certain limitations and research gaps in areas such as populations, cervical spondylosis classification, intervention design, and outcome assessment criteria.Therefore, there is an urgent need to develop more targeted intervention strategies, establish standardized outcome evaluation systems, and conduct in-depth mechanistic studies to further validate the clinical efficacy and practical application of Health Qigong in the management of cervica","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"92 ","pages":"Article 103180"},"PeriodicalIF":3.3,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143976461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mariane Elivânia Silva , Evelin Beatriz Bezerra de Melo , Maria Améllia Lopes Cabral , Laura Lima Souza , Silmara de Oliveira Silva , Nahadja Tahaynara Barros Leal , Jucielly Ferreira da Fonseca , Rodrigo Assis Neves Dantas , Daniele Vieira Dantas
{"title":"Effects of acupuncture on the signs and symptoms of people with rheumatic diseases: A scoping review","authors":"Mariane Elivânia Silva , Evelin Beatriz Bezerra de Melo , Maria Améllia Lopes Cabral , Laura Lima Souza , Silmara de Oliveira Silva , Nahadja Tahaynara Barros Leal , Jucielly Ferreira da Fonseca , Rodrigo Assis Neves Dantas , Daniele Vieira Dantas","doi":"10.1016/j.ctim.2025.103183","DOIUrl":"10.1016/j.ctim.2025.103183","url":null,"abstract":"<div><h3>Introduction</h3><div>Rheumatic diseases constitute a wide range of chronic diseases that mainly affect the musculoskeletal system. They are characterized by inflammatory and degenerative processes that affect synovial joints, bones, muscles, and connective tissues. In addition, many rheumatological diseases have an autoimmune nature. This diversity of conditions results in a wide range of symptoms and degrees of severity, with a significant impact on patients' quality of life, compromising their daily activities and leading to a decline in mental health, including depressive symptoms and feelings of inadequacy.</div></div><div><h3>Objective</h3><div>To map the scientific evidence in the literature on the effects of acupuncture on the signs and symptoms of people with rheumatic diseases.</div></div><div><h3>Methods</h3><div>This is a scoping review, formulated according to the guidelines of the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews checklist.</div></div><div><h3>Results</h3><div>After the identification, screening and eligibility process, 18 studies were included in this review. All were published between 2002 and 2023; 33.33 % were published in China; and 50 % correspond to clinical trials. The most frequently cited diseases were: acute osteoarthritis or acute knee osteoarthritis (27.77 %); fibromyalgia (27.77 %); and rheumatoid arthritis (27.77 %). The effects of acupuncture on the signs and symptoms of people with rheumatic diseases are pain relief, improved quality of life, improved joint function, increased range of motion, anti-inflammation, reduced fatigue, decreased depression and anxiety symptoms, reduced medication use, immune system regulation, and increased finger mobility.</div></div><div><h3>Conclusions</h3><div>Acupuncture has beneficial effects on the signs and symptoms of people with rheumatic diseases, constituting a modality which can be easily and quickly applied by any healthcare professional, as long as they are properly trained.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"91 ","pages":"Article 103183"},"PeriodicalIF":3.3,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143873898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Run-qing Miao , Feng-ya Zhu , Tian-yu Wang , Shao Yin , Chen Shuai , Tao Li , Zhi Li , Lan Luo , Bin Yang
{"title":"The effectiveness and safety of acupuncture for post-stroke depression: An overview of systematic reviews","authors":"Run-qing Miao , Feng-ya Zhu , Tian-yu Wang , Shao Yin , Chen Shuai , Tao Li , Zhi Li , Lan Luo , Bin Yang","doi":"10.1016/j.ctim.2025.103178","DOIUrl":"10.1016/j.ctim.2025.103178","url":null,"abstract":"<div><h3>Background</h3><div>In recent years, research on acupuncture for post-stroke depression (PSD) has grown significantly, yet findings remain inconsistent. Few researchers have conducted comprehensive assessments of systematic reviews (SRs) in this area. Consequently, there is a need for a thorough and objective synthesis of clinical evidence regarding acupuncture's effectiveness in treating PSD.</div></div><div><h3>Objective</h3><div>To evaluate and synthesize evidence on the efficacy and safety of acupuncture for PSD through systematic reviews, offering valuable insights for clinical practice and guiding future research directions.</div></div><div><h3>Methods</h3><div>We searched PubMed, Embase, Web of Science, Cochrane Library, CNKI, SinoMed, Wanfang, VIP and Google Scholar databases for relevant literature. The search covered publications from database inception to September 10, 2024. Literature selection and data extraction were independently performed by two reviewers. The methodological quality, bias risk, and evidence level of included SRs were assessed using AMSTAR 2, ROBIS, and GRADE tools. The corrected covered area (CCA) was calculated to assess overlap in original studies. Data from included SRs were subjected to quantitative or descriptive analysis.</div></div><div><h3>Results</h3><div>A total of 38 SRs on acupuncture for PSD were included. After assessment using AMSTAR 2, one SR was rated as moderate quality, two as low quality, and 35 as very low quality. According to ROBIS, 21 SRs were classified as high risk of overall bias, and 17 as low risk. Acupuncture showed potential to improve depressive symptoms, stroke-related symptoms, and activities of daily living in PSD patients, though the quality of evidence is limited. Some studies suggested possible effects on cognitive function, biomarkers, sleep quality, and Traditional Chinese Medicine syndromes, but these findings require further validation with higher-quality research. While no serious adverse effects were reported in the reviewed studies, more rigorous safety evaluations are needed before definitive conclusions about acupuncture's safety for PSD can be made.</div></div><div><h3>Conclusion</h3><div>Acupuncture shows potential as a treatment for PSD, though more high-quality research is needed to establish its effectiveness and safety. Currently, the majority of systematic reviews exhibit deficiencies in protocol pre-registration, documentation of excluded studies, and disclosure of funding sources, resulting in systematic reviews of suboptimal quality. Current evidence suggests possible benefits for depressive symptoms, stroke-related symptoms, activities of daily living, cognitive function, biomarkers, sleep quality, and TCM syndromes, but these findings should be interpreted cautiously given the limitations in study quality. Further high-quality studies are needed to confirm the efficacy and safety of acupuncture for PSD.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"91 ","pages":"Article 103178"},"PeriodicalIF":3.3,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143860091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Enhancing methodological rigor: Re-evaluating statistical model selection in Tian et al.’s Baduanjin study","authors":"Shanshan Wu","doi":"10.1016/j.ctim.2025.103166","DOIUrl":"10.1016/j.ctim.2025.103166","url":null,"abstract":"","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"91 ","pages":"Article 103166"},"PeriodicalIF":3.3,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143957680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}