{"title":"Effect of acupressure on venous access procedural pain in children: A systematic review and meta-analysis","authors":"Seyed Javad Hosseini , Matin Abdollahi Yousefabady , Seyed Reza Hosseini , Mahbobeh Firooz","doi":"10.1016/j.ctim.2025.103219","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>Effective pain management during venous access in children is a clinical priority, but evidence on acupressure remains inconclusive. This study aimed to evaluate the effectiveness of acupressure on venous access pain in children.</div></div><div><h3>Methods</h3><div>A comprehensive literature search was conducted across multiple electronic databases, including PubMed, Scopus, Web of Science, CENTRAL, ClinicalTrials.gov, and Google Scholar. Relevant studies were identified using a combination of keywords related to the research objective, covering all available records up to January 15, 2025. Randomized clinical trials (RCTs) comparing the effects of acupressure on pain intensity during catheter insertion and venipuncture in children versus a control group were included in the review.</div></div><div><h3>Results</h3><div>This systematic review and meta-analysis included eight studies with a total of 537 pediatric participants. The pooled analysis demonstrated that acupressure significantly reduced pain intensity during peripheral catheter insertion and venipuncture compared to the control group (SMD: −2.30; 95 % CI: −3.20 to −1.40; Z = 5.01, P < 0.001, I² = 93.6 %). Subgroup analysis further indicated that acupressure effectively decreased pain severity for both peripheral catheter insertion (SMD: −1.99; 95 % CI: −3.45 to −0.54) and venipuncture (SMD: −2.61; 95 % CI: −3.62 to −1.61), with statistically significant results.</div></div><div><h3>Conclusions</h3><div>Given that only two studies met high-quality criteria and the certainty of the overall evidence remains very low, the interpretation of findings should be approached with caution. To enhance the robustness of future evidence, there is a pressing need for rigorously designed randomized trials incorporating placebo control groups and proper allocation concealment.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"93 ","pages":"Article 103219"},"PeriodicalIF":3.5000,"publicationDate":"2025-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Complementary therapies in medicine","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0965229925000949","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"INTEGRATIVE & COMPLEMENTARY MEDICINE","Score":null,"Total":0}
引用次数: 0
Abstract
Background
Effective pain management during venous access in children is a clinical priority, but evidence on acupressure remains inconclusive. This study aimed to evaluate the effectiveness of acupressure on venous access pain in children.
Methods
A comprehensive literature search was conducted across multiple electronic databases, including PubMed, Scopus, Web of Science, CENTRAL, ClinicalTrials.gov, and Google Scholar. Relevant studies were identified using a combination of keywords related to the research objective, covering all available records up to January 15, 2025. Randomized clinical trials (RCTs) comparing the effects of acupressure on pain intensity during catheter insertion and venipuncture in children versus a control group were included in the review.
Results
This systematic review and meta-analysis included eight studies with a total of 537 pediatric participants. The pooled analysis demonstrated that acupressure significantly reduced pain intensity during peripheral catheter insertion and venipuncture compared to the control group (SMD: −2.30; 95 % CI: −3.20 to −1.40; Z = 5.01, P < 0.001, I² = 93.6 %). Subgroup analysis further indicated that acupressure effectively decreased pain severity for both peripheral catheter insertion (SMD: −1.99; 95 % CI: −3.45 to −0.54) and venipuncture (SMD: −2.61; 95 % CI: −3.62 to −1.61), with statistically significant results.
Conclusions
Given that only two studies met high-quality criteria and the certainty of the overall evidence remains very low, the interpretation of findings should be approached with caution. To enhance the robustness of future evidence, there is a pressing need for rigorously designed randomized trials incorporating placebo control groups and proper allocation concealment.
期刊介绍:
Complementary Therapies in Medicine is an international, peer-reviewed journal that has considerable appeal to anyone who seeks objective and critical information on complementary therapies or who wishes to deepen their understanding of these approaches. It will be of particular interest to healthcare practitioners including family practitioners, complementary therapists, nurses, and physiotherapists; to academics including social scientists and CAM researchers; to healthcare managers; and to patients. Complementary Therapies in Medicine aims to publish valid, relevant and rigorous research and serious discussion articles with the main purpose of improving healthcare.