Complementary therapies in medicine最新文献

{"title":"Personalized music and hypnosis interventions in palliative and end-of-life care at home: A randomized controlled pilot study","authors":"Josiane Bissonnette ,&nbsp;Andréanne Côté ,&nbsp;Peter-Gens Desameau ,&nbsp;Mariève Cossette ,&nbsp;Anne Marie Pinard ,&nbsp;Caroline Arbour ,&nbsp;Gabrielle Fortin ,&nbsp;David Ogez ,&nbsp;Pierre Rainville","doi":"10.1016/j.ctim.2025.103281","DOIUrl":"10.1016/j.ctim.2025.103281","url":null,"abstract":"<div><h3>Objectives</h3><div>To evaluate the preliminary effectiveness of a personalized intervention integrating pre-recorded hypnosis and/or music in palliative and end-of-life care, and explore patient preferences and experiences.</div></div><div><h3>Methods</h3><div>Forty patients receiving palliative and end-of-life care at home were recruited and randomly assigned to the experimental group or the control/delayed intervention group. Two intervention sessions were conducted within one week, featuring the following modalities tailored to patient preferences: pre-recorded music, hypnosis, or a combination of music and hypnosis. Participants provided self-ratings of their symptoms and distress at predetermined time points using the Edmonton Symptom Assessment Scale and the Distress Thermometer. We used a mixed-effects model to address the quantitative objectives, and we conducted a content analysis to meet the qualitative objectives.</div></div><div><h3>Results</h3><div>The intervention program significantly reduced participants’ distress, showing a medium effect size when comparing the intervention sessions to the control sessions. We also found a medium effect size for improved well-being between groups. Intervention modality did not appear to affect the responses. Participants reported calmness and well-being. The voluntary use of these interventions post-experiment emphasizes their relevance for palliative and end-of-life care. The qualitative findings were consistent with the quantitative results, and revealed additional potential uses and ways to improve the intervention.</div></div><div><h3>Conclusion</h3><div>The personalized pre-recorded music and hypnosis interventions appear to be effective in reducing distress and show great potential for enhancing the overall well-being of individuals in palliative and end-of-life care. Further studies are needed to determine how these findings can be applied to a broader population.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"95 ","pages":"Article 103281"},"PeriodicalIF":3.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145426586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A systematic review of the chronic effects of self-myofascial release on athletic performance","authors":"Qi Yang ,&nbsp;Kim Geok Soh ,&nbsp;Mohamad Aris Bin Mohd Moklas ,&nbsp;Mengjiao Wang ,&nbsp;Xiaoyang Pan ,&nbsp;Kui Ma","doi":"10.1016/j.ctim.2025.103263","DOIUrl":"10.1016/j.ctim.2025.103263","url":null,"abstract":"<div><h3>Background</h3><div>Self-myofascial release (SMR) is widely used by athletes and coaches during warm up and recovery to increase joint range of motion. Its long term effects on performance are less clear.</div></div><div><h3>Objective</h3><div>To evaluate the chronic effects, defined as at least 4 weeks, of SMR interventions on athletes physical fitness and sport specific performance, focusing on flexibility, strength, balance, and skill execution.</div></div><div><h3>Design</h3><div>Systematic review.</div></div><div><h3>Data sources</h3><div>PubMed, SPORTDiscus, Web of Science, and Scopus were searched in February 2025 in line with PRISMA.</div></div><div><h3>Eligibility criteria</h3><div>Experimental studies in peer reviewed English journals that examined SMR for 4 weeks or longer and reported performance related outcomes in athletes.</div></div><div><h3>Results</h3><div>Of 1391 records screened, 12 studies met inclusion, totaling 388 athletes aged 12–30 from soccer, tennis, water polo, volleyball, and mixed sports. Most studies reported significant gains in joint mobility, especially hip and shoulder flexibility. Several studies also showed moderate improvements in strength, such as maximal voluntary contraction and jump height, and in dynamic balance measured by the Y-Balance Test. Effects on static balance, isokinetic strength across all planes, and sport specific skills such as serve speed or sprint swimming were variable and often non significant.</div></div><div><h3>Conclusion</h3><div>Chronic SMR appears effective for improving flexibility and dynamic balance in athletes and may confer additional benefits for strength and motor control. Heterogeneity in protocols, comparators, and outcome measures, along with modest methodological quality, limits firm conclusions. More high quality, sport specific trials are needed to define optimal SMR parameters across training phases.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"95 ","pages":"Article 103263"},"PeriodicalIF":3.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145312576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical evidence on acupuncture for symptom improvement in multiple sclerosis","authors":"Yao Chen ,&nbsp;Yang Cui ,&nbsp;Xinyu Zhou ,&nbsp;Shuo Zhang ,&nbsp;Ze Wang ,&nbsp;Juandi Yang ,&nbsp;Xiangxin Zeng ,&nbsp;Yuhuai Guo ,&nbsp;Zhongren Sun ,&nbsp;Hongna Yin","doi":"10.1016/j.ctim.2025.103276","DOIUrl":"10.1016/j.ctim.2025.103276","url":null,"abstract":"<div><h3>Background</h3><div>Clinical trials on acupuncture for multiple sclerosis (MS) have been growing, but the findings are ongoing controversy.</div></div><div><h3>Objective</h3><div>To evaluate the existing randomized clinical trials (RCTs) for evidence of the efficacy of acupuncture on MS.</div></div><div><h3>Methods</h3><div>We searched PubMed, Embase, CENTRAL, Web of Science, four Chinese-language databases, clinical research registration, gray literature, and reference lists of the selected studies. We evaluated the risk of bias in the included studies with RoB 2, and performed meta-analysis, subgroup analysis, meta-regression, and publication bias detection using STATA version 15.1. Moreover, we assessed the certainty of evidence using the GRADE approach. The protocol for this review was registered with PROSPERO (Prospective Register of Systematic Reviews) (CRD42024530800).</div></div><div><h3>Results</h3><div>A total of 11 RCTs (with 574 patients) were included in the study. The meta-analysis results showed that acupuncture, when combined with medicine, is more effective at improving disability status and enhancing the quality of life than medicine alone Acupuncture-related adverse events were rare and mild. The evidence grade was generally low because of the substantial heterogeneity among studies.</div></div><div><h3>Conclusions</h3><div>Acupuncture therapies are potential treatment options for MS, and are relatively safe. However, owing to the limitations of this study, these conclusions should be interpreted with caution.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"95 ","pages":"Article 103276"},"PeriodicalIF":3.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145399970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between the treatment frequency and efficacy of acupuncture: A scoping review of clinical trials","authors":"Guodong Li ,&nbsp;Xinyu Hu ,&nbsp;Jingli Xing ,&nbsp;Yiying Wang ,&nbsp;Chenlu Wang ,&nbsp;Wennan Yu ,&nbsp;Jie Lian ,&nbsp;Huijuan Cao","doi":"10.1016/j.ctim.2025.103304","DOIUrl":"10.1016/j.ctim.2025.103304","url":null,"abstract":"<div><h3>Objective</h3><div>To consolidate and analyze the existing evidence on the relationship between acupuncture treatment frequency and its clinical efficacy, clarify research status, trends, and core issues, and provide evidence-based insights for optimizing acupuncture treatment protocols.</div></div><div><h3>Methods</h3><div>Following the Arksey and O’Malley scoping review framework and PRISMA-ScR guidelines, nine databases were searched from inception to February 15, 2025. Associations among frequency, disease, and effectiveness were visualized using heat maps and bubble charts. Between-group differences (high-frequency: more than 3 sessions/week; low-frequency: no more than 3 sessions/week) and their influencing factors were summarized.</div></div><div><h3>Results</h3><div>Ninety-four studies were included. There was a significant disease-specific, nonlinear relationship between acupuncture frequency and efficacy. High-frequency acupuncture (&gt; 3 sessions/week) demonstrated marked advantages in treating degenerative spinal/joint diseases, particularly during acute phases or for short-term symptom relief especially. In contrast, peripheral neuropathies showed lower sensitivity to frequency variations. Efficacy enhancement did not depend solely on increased frequency, however. Instead, we found a \"J-shaped curve\" and plateau effects. Significant interactions existed between frequency and other acupuncture parameters, with their importance varying by disease and treatment goals. The current literature evidence shows significant heterogeneity in its various definitions of treatment frequency, though there is an obvious a paucity of low-frequency studies.</div></div><div><h3>Conclusion</h3><div>Optimizing acupuncture frequency requires dynamic adjustments based on disease type, pathological stage, primary treatment goals, and synergistic effects with other treatment parameters. Current evidence remains limited by methodological quality and parameter interaction complexity, precluding the definition of a universally \"optimal frequency.\" Future research should prioritize sequential factorial trials, standardized frequency criteria, and enhanced health-economic evaluations to advance the precision of acupuncture therapy.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"95 ","pages":"Article 103304"},"PeriodicalIF":3.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145430611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and safety of traditional Chinese exercises in cardiac rehabilitation of patients after percutaneous coronary intervention: A systematic review and meta-analysis","authors":"Wang Jiale ,&nbsp;Liu Longcheng ,&nbsp;Yuan Haisheng ,&nbsp;Yu Qiushuang ,&nbsp;Ji Xiaodi ,&nbsp;Wang Anqi ,&nbsp;Zhang Ying ,&nbsp;Ma Lihong","doi":"10.1016/j.ctim.2025.103302","DOIUrl":"10.1016/j.ctim.2025.103302","url":null,"abstract":"<div><h3>Purpose</h3><div>Percutaneous coronary intervention (PCI) is one of the most important therapies in patients with coronary heart disease (CHD). However, there are still many problems, such as in-stent restenosis, recurrent angina pectoris, postoperative anxiety and depression. Traditional Chinese exercise (TCE) therapies belong to the aerobic exercise of low and medium intensity which movements are soft and the combination of movement and static, which may have a certain efficacy on cardiac rehabilitation of patients after PCI. Therefore, this study systematically reviewed the reported clinical studies of TCE on cardiac rehabilitation in patients after PCI to explore its efficacy and safety.</div></div><div><h3>Methods</h3><div>We searched for RCTs on patients after PCI in 8 Chinese and English databases from their inception to Aug 2024. We included patients after PCI, with the intervention group receiving TCE (alone and/or combined with conventional treatment and/or exercise) and the control group receiving only conventional treatment and/or exercise. We screened the literatures and extracted the data. And we used the Cochrane “Risk of bias” tool and GRADE tool to assess the quality of studies and evidence. We used RevMan 5.4 to analyze the results.</div></div><div><h3>Results</h3><div>Fifty-three studies involving 4700 patients after PCI were included. TCE therapy includes Baduanjin, Tai Chi, Wuqinxi and Yi Jinjing. Conventional treatment(CT) included basic drugs, routine nursing, nutritional guidance and psychological intervention. Conventional exercise (CE) included walking, jogging or other aerobic exercise, resistance training, balance and flexibility training. Methodological quality was of high risk of bias in blinding of participants and personnel as well as unclear of bias in blinding of outcome assessment and allocation concealment. Grade evaluation results suggested low or very low quality of evidence. For the incidence of major adverse cardiovascular events rate, left ventricular ejection fraction, NT-ProBNP, six-minute walk distance, left ventricular end diastolic diameter, left ventricular end-systolic diameter, VO₂ max, anaerobic threshold, metabolite equivalents, seattle angina questionnaire and short form 36 health survey questionnaire, treatment group is superior to control group (P＜0.05). For VO₂ peak, there was no significant difference between the two groups (P＞0.05).</div></div><div><h3>Conclusions</h3><div>The results of this study showed that TCE may have efficacy in reducing the incidence of MACE, improving the cardiac function, exercise endurance and quality of life of patients after PCI. And the efficacy of the TCE therapy combined with CT and/or CE may be better than that of the CT and/or CE and the safety may be better.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"95 ","pages":"Article 103302"},"PeriodicalIF":3.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145437759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “AI-assisted drawing therapy for children with ADHD: A randomised controlled trial” [Complement Ther Med 94 (2025) 103262]","authors":"Jing Xu ,&nbsp;Runqing Lin ,&nbsp;Aijia Zhang ,&nbsp;Qiang Chen ,&nbsp;Dexin Li ,&nbsp;Jiajie Chen ,&nbsp;Minglu Song ,&nbsp;Shumei Chen ,&nbsp;Bingjiao Yang ,&nbsp;Linyang Li ,&nbsp;Haotian Xu ,&nbsp;Jinlin Peng ,&nbsp;Yanrong Tang ,&nbsp;Wenhua Yang ,&nbsp;Xuexing Luo ,&nbsp;Xiang Zhou ,&nbsp;Jue Wang ,&nbsp;Guanghui Huang","doi":"10.1016/j.ctim.2025.103277","DOIUrl":"10.1016/j.ctim.2025.103277","url":null,"abstract":"","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"95 ","pages":"Article 103277"},"PeriodicalIF":3.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145421450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of qigong for physical and psychological well-being in pregnancy: A multicenter randomized controlled trial","authors":"Emine Dundar Ahi ,&nbsp;Ozlem Kuculmez ,&nbsp;Sevgi Ikbali Afsar ,&nbsp;Rahsan Eyup Dogan","doi":"10.1016/j.ctim.2025.103284","DOIUrl":"10.1016/j.ctim.2025.103284","url":null,"abstract":"<div><h3>Background</h3><div>Psychological stress and anxiety during pregnancy can adversely affect both maternal and fetal health. Qigong, a traditional Chinese mind–body exercise, is believed to promote physical and mental well-being during pregnancy. This study aimed to investigate the effects of qigong on anxiety, stress, and exercise self-efficacy in pregnant women.</div></div><div><h3>Methods</h3><div>This multicenter randomized controlled clinical trial included pregnant women in their second trimester attending prenatal education classes at Baskent University and Alaaddin Keykubat University. Women in the first or third trimester with uncontrolled systemic diseases, high-risk pregnancies, or irregular attendance were excluded. Participants were randomly assigned via Randomizer.org to either the Qigong group or the control group. The Qigong group performed Baduanjin qigong exercises for 30–45 min, three times a week, while the control group received standard prenatal counseling. Demographic data were recorded. All participants completed the Pregnancy-Related Anxiety Scale (PrAS), Pregnancy Stress Rating Scale (PSRS), and Pregnancy Exercise Self-Efficacy Scale (P-ESES).</div></div><div><h3>Results</h3><div>A total of 102 pregnant women were analyzed (qigong group: 52; control group: 50). The mean age was 27.95 ± 3.66 years, and the mean gestational week was 26.94 ± 2.12. The qigong group showed significantly lower systolic and diastolic blood pressure increases compared to the control group (p &lt; 0.05). Exercise self-efficacy scores increased significantly in the qigong group (p &lt; 0.05). Pregnancy-related anxiety and stress scores, including all subscales, showed significant improvement in the qigong group (p &lt; 0.05), with no significant changes in the control group (p &gt; 0.05).</div></div><div><h3>Conclusions</h3><div>Baduanjin qigong was effective in reducing anxiety and stress levels and improving exercise self-efficacy in pregnant women. This non-pharmacological intervention may offer a safe, supportive approach to mental well-being during pregnancy.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"95 ","pages":"Article 103284"},"PeriodicalIF":3.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145426514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of 10.6-μm laser therapy for diabetic peripheral neuropathy: A double-blind, randomized controlled trial","authors":"Yue Yin ,&nbsp;Zouqin Huang ,&nbsp;Yuxia Li ,&nbsp;Yi Chen ,&nbsp;Ke Cheng ,&nbsp;Haiping Deng ,&nbsp;Weibo Lv ,&nbsp;Yan Wang ,&nbsp;Xueyong Shen ,&nbsp;Ling Zhao ,&nbsp;Lin Lin","doi":"10.1016/j.ctim.2025.103259","DOIUrl":"10.1016/j.ctim.2025.103259","url":null,"abstract":"<div><h3>Objective</h3><div>To observe the clinical effects of 10.6-μm laser moxibustion (LM) on diabetic peripheral neuropathy (DPN) and quality of life in patients.</div></div><div><h3>Methods</h3><div>Sixty-eight patients with DPN were randomly assigned to two groups in a 1:1 ratio and received LM or sham LM 3 times/week for a total of 12 treatments. Outcome parameters were assessed at baseline, at Weeks 2 and 4 of treatment, and at 4 and 8 weeks post-treatment (Weeks 8 and 12) using Michigan Neuropathy Screening Instrument (MNSI) and Diabetes-Specific Quality of Life (DSQL) scores, nerve conduction velocity (NCV), and blood rheology parameters.</div></div><div><h3>Results</h3><div>Most (58/68) patients completed the trial. MNSI scores were significantly lower at every time point (<em>P</em> &lt; 0.01), and DSQL scores were significantly lower at Weeks 4, 8, and 12 (<em>P</em> &lt; 0.001), compared with baseline in both groups. The LM group had lower MNSI scores at Week 4 (<em>P</em> &lt; 0.05), and lower DSQL scores at Weeks 4, 8, and 12 (<em>P</em> &lt; 0.05) compared with the sham LM group. At Week 4, there was no significant between-group difference in NCV (<em>P</em> &gt; 0.05). Post-treatment, there were no significant differences in blood rheology parameters compared with baseline within each group (<em>P</em> &gt; 0.05). Whole blood high-shear reductive viscosity and red blood cell rigidity index were significantly lower in the LM group than in the sham LM group (<em>P</em> &lt; 0.01). No serious adverse events were recorded.</div></div><div><h3>Conclusion</h3><div>Treatment with 10.6-μm LM improved clinical symptoms and quality of life in patients with DPN.</div></div><div><h3>Clinical Trial Registration</h3><div>Chinese Clinical Trial Registry, ChiCTR2000029329. Registered 25 January 2020, <span><span>https://www.chictr.org.cn/showproj.html?proj=48490</span><svg><path></path></svg></span></div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"95 ","pages":"Article 103259"},"PeriodicalIF":3.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145299007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and safety of acupressure for primary dysmenorrhea: A systematic review and meta-analysis of randomized controlled trials","authors":"Xiaohan Yu ,&nbsp;Bohong Liu ,&nbsp;Jiaxin Li ,&nbsp;Yuanjie Gao ,&nbsp;Jianpeng Chen ,&nbsp;Rongming Qi ,&nbsp;Yuxuan Yuan ,&nbsp;Yaru Liu","doi":"10.1016/j.ctim.2025.103272","DOIUrl":"10.1016/j.ctim.2025.103272","url":null,"abstract":"<div><h3>Objective</h3><div>This systematic review aimed to evaluate the existing randomized controlled trials (RCTs) for evidence of the association between using acupressure and reducing pain and related symptoms of primary dysmenorrhea (PD).</div></div><div><h3>Methods</h3><div>Six electronic databases were searched for published reports on RCTs—from database inception until May 2025—that compared the use of acupressure with that of placebo acupressure, oral medication, or usual treatment and measured the intensity of menstrual pain and related symptoms. Two independent reviewers extracted and assessed the data. Risk of bias was assessed for each article; the meta-analysis was conducted according to the type of control. Results are presented as mean differences (MDs) or standardised mean differences (SMDs) and 95 % confidence intervals (CIs).</div></div><div><h3>Results</h3><div>In total, 23 RCTs were included in the systematic review and data from 20 RCTs were evaluated in the meta-analysis. Most studies showed a low or unclear risk of bias. We found that using acupressure was more effective in reducing menstrual pain than using placebo acupressure (MD = −1.58; 95 % CI, [−1.96, −1.20]), oral medication (MD = −1.11; 95 % CI, [−1.79, −0.43]), or usual treatment (MD = −1.29; 95 % CI, [−1.77, −0.80]). The adverse events, reported in only two studies, were mild.</div></div><div><h3>Conclusion</h3><div>Acupressure can effectively reduce the pain and related symptoms of PD, though the current evidence is of low quality. Future studies with rigorous designs and larger sample sizes are warranted to verify the efficacy and safety of acupressure. Subsequent findings should be incorporated into clinical practice and nursing care to refine the treatment strategies for PD.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"95 ","pages":"Article 103272"},"PeriodicalIF":3.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145360721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Complementary therapies for chronic knee pain: A placebo-controlled RCT of Reiki and mindfulness","authors":"Adam W. Hanley ,&nbsp;Yoshio Nakamura ,&nbsp;Robert R. Edwards ,&nbsp;Ayaka Lingard ,&nbsp;Kennedi Childs ,&nbsp;Jim Faulkner ,&nbsp;Ruthie Schnitt ,&nbsp;Samantha Vaca-St. Claire ,&nbsp;Elizabeth Bridge ,&nbsp;Eric L. Garland","doi":"10.1016/j.ctim.2025.103278","DOIUrl":"10.1016/j.ctim.2025.103278","url":null,"abstract":"<div><h3>Context</h3><div>Knee osteoarthritis (KOA) is a prevalent chronic pain condition that significantly impairs quality of life and is often treated with interventions that carry risks or provide limited relief. Reiki, a non-invasive complementary therapy, has shown early promise for pain management but lacks rigorous evaluation among American adults with KOA.</div></div><div><h3>Objectives</h3><div>This study evaluated the specific efficacy of Reiki and mindfulness for adults with chronic KOA pain compared to sham and waitlist control conditions.</div></div><div><h3>Methods</h3><div>In this placebo-controlled randomized trial, 164 adults with physician-confirmed KOA were assigned to one of four groups: Reiki, sham Reiki (i.e., Feiki), mindfulness meditation, or a waitlist control. Active treatments were delivered in four weekly 30-minute sessions.</div></div><div><h3>Results</h3><div>KOA symptom severity, assessed using the WOMAC at baseline, 1-month, and 2-month follow-ups, significantly improved in both the Reiki (<em>p</em> = .02) and mindfulness (p &lt; .001) groups compared to waitlist controls. Mindfulness significantly outperformed Feiki (<em>p</em> = .004). Reiki demonstrated effects comparable to mindfulness (p = .22). Clinically meaningful reductions in symptoms (&gt;30 %) were reported by 55 % of participants in the Reiki and mindfulness groups, compared to 20 % in the Feiki group and 13 % in the waitlist group. High retention (96 %) and successful blinding support the feasibility and internal validity of this approach.</div></div><div><h3>Conclusions</h3><div>These findings indicate that both Reiki and mindfulness may offer effective, well-tolerated, and time-efficient alternatives for managing KOA-related pain, with meaningful symptom improvement after just two hours of intervention. Larger trials are warranted to confirm efficacy and explore long-term outcomes and underlying mechanisms.</div></div>","PeriodicalId":10545,"journal":{"name":"Complementary therapies in medicine","volume":"95 ","pages":"Article 103278"},"PeriodicalIF":3.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145437753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}