Cognitive Neurodynamics最新文献

筛选
英文 中文
Fundamental questions on closed-loop neuromodulation: a control theory perspective. 闭环神经调节的基本问题:控制理论的视角。
IF 3.9 3区 工程技术
Cognitive Neurodynamics Pub Date : 2026-12-01 Epub Date: 2026-05-07 DOI: 10.1007/s11571-026-10452-0
Min Wang, Li Zhang, Zhen Liang, Gan Huang
{"title":"Fundamental questions on closed-loop neuromodulation: a control theory perspective.","authors":"Min Wang, Li Zhang, Zhen Liang, Gan Huang","doi":"10.1007/s11571-026-10452-0","DOIUrl":"https://doi.org/10.1007/s11571-026-10452-0","url":null,"abstract":"<p><p>Closed-loop neuromodulation aims to adjust therapeutic stimulation in real time based on ongoing neural or physiological signals. Despite growing clinical adoption, most implementations rely on heuristic rules rather than a principled systems-and-control formulation. This paper, motivated by discussions from the Brain Theory Seminar (Shanghai, March 2025), develops such a formulation around seven fundamental questions-mechanism (Q1), plant nature (Q2), state measurement (Q3), actuation (Q4), modeling (Q5), objectives (Q6), and constraints (Q7)-and, for each, provides a knowledge-based review synthesizing current understanding together with a prospective scientific opinion on unresolved issues. Five recurring themes unify the seven questions: (i) nonstationarity as the default operating condition, (ii) structural partial observability and under-actuation, (iii) closed-loop confounding between stimulation and measurement, (iv) the primacy of hard constraints over unconstrained optimization, and (v) the necessity of layered governance separating performance seeking from safety enforcement. We argue that the neural plant is fundamentally different from classical engineered systems in ways that reshape what can be sensed, modeled, actuated, and verified; accordingly, we reframe therapeutic goals from setpoint tracking toward set-based regulation within a therapeutic window, and we treat safety, ethics, and accountability not as external add-ons but as architectural primitives that define the admissible design space. We close with a discussion synthesizing system-level barriers and near-term architectural directions, including bidirectional brain-computer interfaces, hybrid learning-and-control pipelines with independent safety supervision, and digital twins as regulated test harnesses.</p>","PeriodicalId":10500,"journal":{"name":"Cognitive Neurodynamics","volume":"20 1","pages":"88"},"PeriodicalIF":3.9,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13153344/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147867236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring electromagnetic induction and astrocyte influence in excitatory-inhibitory coupling neuron network. 探索电磁感应和星形胶质细胞对兴奋-抑制耦联神经元网络的影响。
IF 3.9 3区 工程技术
Cognitive Neurodynamics Pub Date : 2026-12-01 Epub Date: 2026-04-21 DOI: 10.1007/s11571-026-10451-1
Zhongquan Gao, Peihua Feng
{"title":"Exploring electromagnetic induction and astrocyte influence in excitatory-inhibitory coupling neuron network.","authors":"Zhongquan Gao, Peihua Feng","doi":"10.1007/s11571-026-10451-1","DOIUrl":"https://doi.org/10.1007/s11571-026-10451-1","url":null,"abstract":"<p><p>This study investigates how electromagnetic induction and astrocytic modulation jointly influence firing dynamics and synchronization in excitatory-inhibitory neuronal networks. Using a computational model that integrates pyramidal neurons, interneurons, and astrocytes with memristor-based electromagnetic feedback and calcium-dependent signaling, we demonstrate that electromagnetic induction generally suppresses neuronal firing, but this effect can be bidirectionally modulated by astrocytic feedback depending on intracellular calcium levels. Key findings reveal the non-linear dependence of neuronal responses on astrocytic calcium thresholds and [Formula: see text] dynamics; the distinct roles of excitatory, inhibitory, and astrocytic coupling in regulating network synchrony and chimera states; and the existence of parameter regimes where astrocytic feedback is overridden under strong electromagnetic induction. These results highlight the critical interplay between electromagnetic and glial mechanisms in shaping network activity, offering insights for models of neural synchronization and potential therapeutic strategies for epilepsy and related disorders.</p>","PeriodicalId":10500,"journal":{"name":"Cognitive Neurodynamics","volume":"20 1","pages":"84"},"PeriodicalIF":3.9,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13100091/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147764802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Changes in aperiodic EEG activity following acupuncture stimulation in stroke. 针刺刺激脑卒中后非周期性脑电图活动的变化。
IF 3.9 3区 工程技术
Cognitive Neurodynamics Pub Date : 2026-12-01 Epub Date: 2026-05-16 DOI: 10.1007/s11571-026-10466-8
Zhicai Hu, Zhen Zhang, Fan Xu, Sixian Wu, Jiang Wang, Guiping Li, Haitao Yu
{"title":"Changes in aperiodic EEG activity following acupuncture stimulation in stroke.","authors":"Zhicai Hu, Zhen Zhang, Fan Xu, Sixian Wu, Jiang Wang, Guiping Li, Haitao Yu","doi":"10.1007/s11571-026-10466-8","DOIUrl":"https://doi.org/10.1007/s11571-026-10466-8","url":null,"abstract":"<p><p>Electroencephalography (EEG) enables the direct measurement of stroke-related brain activity, which is crucial for objectively evaluating therapeutic effects of neuromodulatory interventions in stroke. Numerous studies indicate that EEG spectra comprise a mixture of periodic oscillations and aperiodic background; however, how aperiodic activity, distinct from oscillatory components, characterizes and quantifies external stimulation remains unclear. In this paper, we parameterized the power spectra of EEG recorded from 30 stroke subjects with acupuncture stimulation and investigated the changes of oscillatory and aperiodic brain activity following acupuncture stimulation. For the oscillatory components, we found that acupuncture increased both the power and center frequency of alpha oscillations in the left fronto-parietal cortex, indicating a shift toward faster and more strongly synchronized activity in the lesioned regions. Next, analysis of aperiodic brain activity demonstrated widespread decreases in the aperiodic exponent and offset, most prominently in the ipsilesional hemisphere. These globally and spatially coherent changes suggest that aperiodic dynamics are highly sensitive to acupuncture, reflecting coordinated changes in the background spectral organization. Furthermore, analyses of both periodic and aperiodic features revealed that acupuncture improved interhemispheric symmetry, with particularly pronounced effects observed in alpha center frequency, alpha power, and the aperiodic exponent. Collectively, this study extracted oscillatory and aperiodic spectral features to characterize EEG activity, identified alpha center frequency, alpha power, and the aperiodic exponent as potential biomarkers of acupuncture-induced changes in stroke, and provided evidence for the modulatory effects of peripheral acupuncture stimulation on brain activity.</p>","PeriodicalId":10500,"journal":{"name":"Cognitive Neurodynamics","volume":"20 1","pages":"94"},"PeriodicalIF":3.9,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13180013/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147970827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A novel motor imagery brain-computer interface classification framework based on augmented covariance matrix: deep Riemannian geometry learning with self-attention mechanism. 一种新的基于增广协方差矩阵的运动意象脑机接口分类框架:带自注意机制的深度黎曼几何学习。
IF 4.5 3区 工程技术
Cognitive Neurodynamics Pub Date : 2026-12-01 Epub Date: 2026-09-21 DOI: 10.1007/s11571-026-10548-7
Tian Yan, Aimin Zhang, Zengyao Yang, Hechong Su, Yidan Ma, Yue Wu, Li Yan, Yichen Wang, Fei Guo, Jianfu Cao
{"title":"A novel motor imagery brain-computer interface classification framework based on augmented covariance matrix: deep Riemannian geometry learning with self-attention mechanism.","authors":"Tian Yan, Aimin Zhang, Zengyao Yang, Hechong Su, Yidan Ma, Yue Wu, Li Yan, Yichen Wang, Fei Guo, Jianfu Cao","doi":"10.1007/s11571-026-10548-7","DOIUrl":"10.1007/s11571-026-10548-7","url":null,"abstract":"<p><p>The rapid development of motor imagery brain-computer interface (MI-BCI) technology has introduced a novel mode of human-machine interaction, drawing significant interest. However, due to the nonlinearity and nonstationarity of motor imagery signals, this communication method faces challenges such as low recognition accuracy and poor stability, which severely hinder the practical application of MI-BCIs. Riemannian geometry techniques, leveraging their non-Euclidean properties, have shown promise in addressing motor imagery signal pattern recognition. Traditional Riemannian geometry methods, however, still suffer from limitations, such as requiring manual feature extraction and resulting in suboptimal classification performance. This paper proposes Aug-SPD-AttentionNet, a deep Riemannian geometry learning framework for MI-BCI classification that combines lagged augmented covariance representations, a learnable high-dimensional embedding layer, and self-attention operations defined on the SPD manifold. The proposed framework employs multiple deep Riemannian learning blocks to extract manifold-aware features and uses a Riemannian self-attention mechanism to capture long-range dependencies among different SPD representations. Aug-SPD-AttentionNet was evaluated on BCI Competition III Dataset IVa, BCI Competition IV Dataset I, and BCI Competition IV Dataset 2a, achieving mean classification accuracies of [Formula: see text], [Formula: see text], and [Formula: see text], respectively. Ablation experiments further demonstrate that the proposed components collectively improve classification performance, increasing the mean accuracy across the three evaluated subjects from 70.60 to 82.62%, corresponding to a 12.03-percentage-point improvement over the baseline SPDNet.</p>","PeriodicalId":10500,"journal":{"name":"Cognitive Neurodynamics","volume":"20 1","pages":"180"},"PeriodicalIF":4.5,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13593989/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149024037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Electroacupuncture modulates cortical functional connectivity and network topology in healthy adults: an fNIRS study. 电针调节健康成人皮质功能连通性和网络拓扑:一项fNIRS研究。
IF 4.5 3区 工程技术
Cognitive Neurodynamics Pub Date : 2026-12-01 Epub Date: 2026-09-30 DOI: 10.1007/s11571-026-10560-x
Xiang Chen, Banghua Yang, Dongyang Shen, Junhua Chen, Dongsheng Xu, Wenxi Li
{"title":"Electroacupuncture modulates cortical functional connectivity and network topology in healthy adults: an fNIRS study.","authors":"Xiang Chen, Banghua Yang, Dongyang Shen, Junhua Chen, Dongsheng Xu, Wenxi Li","doi":"10.1007/s11571-026-10560-x","DOIUrl":"https://doi.org/10.1007/s11571-026-10560-x","url":null,"abstract":"<p><p>Acupuncture has shown clinical benefits in post-stroke rehabilitation, yet its central neural mechanisms remain incompletely understood. In particular, how cortical activation, inter-regional functional connectivity, and brain network topology are modulated during electroacupuncture stimulation has not been systematically characterised. This study aimed to investigate the central effects of verum electroacupuncture (VE) applied to the non-dominant hand in healthy adults. In a randomized, crossover design, functional near-infrared spectroscopy (fNIRS) data were collected from 24 participants during VE and sham electroacupuncture (SE) sessions. Cortical activation was assessed using a general linear model (GLM), functional connectivity (FC) was analysed using lagged cross-correlation, and brain network topology was examined using graph-theoretical metrics. No significant differences in cortical activation were observed between VE and SE. During the needles retention phase, VE significantly reduced functional connectivity between R-MPFC and right primary somatosensory cortex (R-PSC), and between middle MPFC and R-PSC. Graph-theoretical analysis revealed decreased clustering coefficient and increased small-worldness under VE. These findings suggest that VE may optimise brain networks through an connectivity-topology mechanism. Brain networks shifted from excessive localisation toward higher integration. This study establishes a baseline central response profile in healthy individuals and provides theoretical support for the application of electroacupuncture in post-stroke upper-limb rehabilitation. <i>Trial registration</i>: ITMCTR, TRN: ITMCTR2025000595, Registration date: 19 March 2025.</p>","PeriodicalId":10500,"journal":{"name":"Cognitive Neurodynamics","volume":"20 1","pages":"193"},"PeriodicalIF":4.5,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13627537/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149105142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Domain generalized feature embedded learning for calibration-free event-related potentials recognition. 面向无标定事件相关电位识别的领域广义特征嵌入学习。
IF 4.5 3区 工程技术
Cognitive Neurodynamics Pub Date : 2026-12-01 Epub Date: 2026-04-09 DOI: 10.1007/s11571-026-10450-2
Tian-Jian Luo
{"title":"Domain generalized feature embedded learning for calibration-free event-related potentials recognition.","authors":"Tian-Jian Luo","doi":"10.1007/s11571-026-10450-2","DOIUrl":"10.1007/s11571-026-10450-2","url":null,"abstract":"<p><p>Event-related potentials (ERPs) play an important role for building EEG-based brain computer interfaces (BCIs). However, due to the complex and varied spatio-temporal characteristics of ERPs across subjects, data distribution across subjects a very important issue to be solved for constructing calibration-free BCIs. To achieve calibration-free ERPs recognition, we propose a <b>D</b>omain <b>G</b>eneralized <b>F</b>eature <b>E</b>mbedded <b>L</b>earning (DGFEL) method. First, we align the ERPs of each existed subject based on covariance centroids. Then, we enhanced the aligned samples based on xDAWN filter and extract spatio-temporal features. Finally, the spatio-temporal features are further generalized by the decomposed adversarial loss, and we construct a neural network embedding backbone to implement features generalization across subjects. The proposed method has been systematically validated on two benchmark EEG-based ERP datasets, and its classification performance surpasses several state-of-the-art methods as well as deep learning models. Moreover, it effectively captures robust features from existed source subjects, and can be generalized to new subjects without accessing target ERP samples. Our method therefore provides a novel selection to construct calibration-free ERP-BCIs.</p>","PeriodicalId":10500,"journal":{"name":"Cognitive Neurodynamics","volume":"20 1","pages":"77"},"PeriodicalIF":4.5,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13065971/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147671004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The AHEPA EEG benchmark: setting the standard for machine learning in dementia diagnosis, a scoping review. AHEPA脑电图基准:为痴呆症诊断中的机器学习设定标准,范围审查。
IF 4.5 3区 工程技术
Cognitive Neurodynamics Pub Date : 2026-12-01 Epub Date: 2026-05-18 DOI: 10.1007/s11571-026-10464-w
Andreas Miltiadous, Aimilia Ntetska, Vasileios Aspiotis, Efthalia Moustakli, Markos G Tsipouras, Alexandros T Tzallas, Nikolaos Giannakeas, Euripidis Glavas, Pantelis Angelidis, Katerina D Tzimourta
{"title":"The AHEPA EEG benchmark: setting the standard for machine learning in dementia diagnosis, a scoping review.","authors":"Andreas Miltiadous, Aimilia Ntetska, Vasileios Aspiotis, Efthalia Moustakli, Markos G Tsipouras, Alexandros T Tzallas, Nikolaos Giannakeas, Euripidis Glavas, Pantelis Angelidis, Katerina D Tzimourta","doi":"10.1007/s11571-026-10464-w","DOIUrl":"10.1007/s11571-026-10464-w","url":null,"abstract":"<p><p>Accurate and reproducible electroencephalography (EEG)-based classification of dementia remains a key challenge in computational neurodiagnostics. The open-access AHEPA dataset has become the most commonly used benchmark for Alzheimer's disease (AD) and Frontotemporal dementia (FTD) classification, yet reported results vary widely due to methodological inconsistencies. This study presents the first systematic and quantitative benchmark review of all published machine learning approaches applied to the AHEPA dataset. Forty-six studies were reviewed and stratified into three validity tiers, with Validity 1 representing the highest methodological rigor and Validity 3 the lowest.According to their evaluation rigor: (1) subject-level validation (e.g., Leave-One-Subject-Out cross-validation, LOSO-CV), (2) subject-level train/test splits, and (3) epoch-level k-fold cross-validation. Performance metrics were normalized across classification problems. The analysis revealed that methodological rigor is inversely correlated with reported accuracy: for AD versus Cognitively Normal controls, mean accuracy decreased from 90.81% overall to 82.11% in Validity-1 studies; for FTD versus controls, accuracy dropped from 86.53% to 75.18%. Linear regression analyses demonstrated that weaker validation protocols were associated with systematic increases of 7-10% points in reported accuracy, explaining more than half of the observed performance variance. Deep and hybrid models reported the highest nominal accuracies, but under proper validation, traditional algorithms performed comparably, indicating that data leakage often drives apparent improvements. The review also highlights the lack of cross-configuration generalization and the urgent need for adaptive, montage-independent methodologies. Overall, this benchmark establishes the first reproducible reference framework for EEG-based dementia classification on the AHEPA dataset, providing quantitative baselines and validity criteria against which all future studies should be evaluated.</p>","PeriodicalId":10500,"journal":{"name":"Cognitive Neurodynamics","volume":"20 1","pages":"95"},"PeriodicalIF":4.5,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13184051/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147981037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A geometric rs-fMRI connectome descriptor reveals individual stability without robust autism group differences. 几何rs-fMRI连接体描述符揭示了个体的稳定性,没有明显的自闭症组差异。
IF 4.5 3区 工程技术
Cognitive Neurodynamics Pub Date : 2026-12-01 Epub Date: 2026-10-08 DOI: 10.1007/s11571-026-10563-8
Sai Prasanna M S, Senthil Thilak A
{"title":"A geometric rs-fMRI connectome descriptor reveals individual stability without robust autism group differences.","authors":"Sai Prasanna M S, Senthil Thilak A","doi":"10.1007/s11571-026-10563-8","DOIUrl":"https://doi.org/10.1007/s11571-026-10563-8","url":null,"abstract":"<p><p>Autism spectrum disorder (ASD) has resisted reproducible case-control characterization in resting-state functional connectivity, leaving open whether reported group differences reflect genuine biology or methodological variability. We introduce a geometric framework that represents functional connectomes on the symmetric positive-definite Riemannian manifold and quantifies individual deviation as tangent-space dispersion, complemented by normative modeling of graph topology. Using the multi-site Autism Brain Imaging Data Exchange (ABIDE I) cohort (<i>N=1035</i> subjects), we evaluate this descriptor under stringent robustness conditions and report three findings. First, individual connectome geometry is a stable, individually unique descriptor. The magnitude of a subject's deviation is highly reliable across split halves (intraclass correlation ICC[Formula: see text]) but is dominated by an acquisition-site scale, whereas its high-dimensional shape identifies subjects within-session with <i>98.9%</i> accuracy once that scale is removed. Second, the case-control difference in dispersion is null and, by two one-sided equivalence tests against Cohen's <i>d = 0.2</i>, statistically equivalent to zero in all ABIDE I analysis cohorts (full cohort <i>d = -0.007</i>, <i>N = 1035</i>; strict cohort <i>d = +0.038</i>, <i>N = 635</i>); a nominal single-atlas effect (dispersion ratio 1.05, <i>p = 0.046</i>) does not survive multi-atlas reanalysis. Third, acquisition site explains <i>69%</i> of dispersion variance while diagnosis explains <i>0.0001%</i>; deviations form no discrete subtypes and do not predict symptom severity (minimum <i>p=0.15</i> across tested graph-deviation predictors). Geometric dispersion is therefore a reproducible, individually unique connectome descriptor but not a case-control biomarker of ASD, which helps to explain the inconsistency of connectomic findings in autism.</p>","PeriodicalId":10500,"journal":{"name":"Cognitive Neurodynamics","volume":"20 1","pages":"199"},"PeriodicalIF":4.5,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13650096/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149164300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Low-invasive large-field retinal modulation using an extraocular temporal interference stimulation electrode array. 使用眼外颞干扰刺激电极阵列的低侵入性大视场视网膜调制。
IF 4.5 3区 工程技术
Cognitive Neurodynamics Pub Date : 2026-12-01 Epub Date: 2026-10-22 DOI: 10.1007/s11571-026-10573-6
Zhengyang Liu, Jiao Liu, Jing Pang, Xuan Guo, Ling Wang, Xiaoyu Song, Heng Li, Xinyu Chai, Hong Gan, Siyi Gong, Tianruo Guo, Liming Li
{"title":"Low-invasive large-field retinal modulation using an extraocular temporal interference stimulation electrode array.","authors":"Zhengyang Liu, Jiao Liu, Jing Pang, Xuan Guo, Ling Wang, Xiaoyu Song, Heng Li, Xinyu Chai, Hong Gan, Siyi Gong, Tianruo Guo, Liming Li","doi":"10.1007/s11571-026-10573-6","DOIUrl":"https://doi.org/10.1007/s11571-026-10573-6","url":null,"abstract":"<p><p>Retinal prostheses can restore rudimentary visual perception in retinal degenerated patients by electrically stimulating surviving retinal neurons. Conventional implantable systems require intraocular electrode array implantation, which involves complex surgical procedures and substantial invasiveness. Temporal interference stimulation (TIS) achieves noninvasive and focused deep brain stimulation by delivering kilohertz currents with slight frequency differences across stimulation channels (each consisting of a stimulating and a return electrode). Our research team was the first to propose a spatially selective extraocular retinal electrical stimulation and modulation approach using TIS. In this study, we designed a low-invasive extraocular electrode array based on TIS for large-scale, spatially selective retinal ganglion cell (RGC) modulation. The array consists of a stimulating electrode array positioned on the posterior sclera and a return electrode array on the cornea. Using simulation-based modeling, we optimized the number of stimulation channels and electrode configuration to improve spatial selectivity. The optimized electrode array produced convergent RGC activation across a 6 × 6 mm retinal region, with activated RGC receptive field centroids closely aligned with the corresponding stimulating electrodes. By adjusting stimulation intensity, consistent activation areas were achieved across different retinal locations. Furthermore, by leveraging virtual channel modulation, additional activation sites were created, thereby improving the theoretical spatial selectivity without increasing the number of physical electrodes. These results demonstrate the feasibility of low-invasive, large-field, spatially selective retinal neuromodulation using extraocular TIS and provide a theoretical foundation for future retinal prosthetic and therapeutic applications.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at https://doi.org/10.1007/s11571-026-10573-6.</p>","PeriodicalId":10500,"journal":{"name":"Cognitive Neurodynamics","volume":"20 1","pages":"206"},"PeriodicalIF":4.5,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13691027/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149263721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multimodal biometric authentication systems: exploring EEG and signature. 多模态生物识别认证系统:探索脑电图和签名。
IF 3.9 3区 工程技术
Cognitive Neurodynamics Pub Date : 2026-12-01 Epub Date: 2025-12-06 DOI: 10.1007/s11571-025-10389-w
Banee Bandana Das, Chinthala Varnitha Reddy, Ujwala Matha, Chinni Yandapalli, Saswat Kumar Ram
{"title":"Multimodal biometric authentication systems: exploring EEG and signature.","authors":"Banee Bandana Das, Chinthala Varnitha Reddy, Ujwala Matha, Chinni Yandapalli, Saswat Kumar Ram","doi":"10.1007/s11571-025-10389-w","DOIUrl":"https://doi.org/10.1007/s11571-025-10389-w","url":null,"abstract":"<p><p>Biometric traits are unique characteristics of an individual's body or behavior that can be used for identification and authentication. Biometric authentication uses unique physiological and behavioral traits for secure identity verification. Traditional unimodal biometric authentication systems often suffer from spoofing attacks, sensor noise, forgery, and environmental dependencies. To overcome these limitations, our work presents multimodal biometric authentication integrated with the characteristics of electroencephalograph (EEG) signals and handwritten signatures to enhance security, efficiency, and robustness. EEG-based authentication uses the brainwave patterns' intrinsic and unforgeable nature, while signature recognition demonstrates an additional behavioral trait for effectiveness. Our system processes EEG data of an individual with 14-channel readings, and the signature with the images ensures a seamless fusion of both modalities.Combining physiological and behavioral biometrics, our approach will significantly decrease the risk of unimodal authentication, including forgery, spoofing, and sensor failures. Our system, evaluated on a dataset of 30 subjects with genuine and forged data, demonstrates a 97% accuracy. Designed for small organizations, the modular structure, low computation algorithms, and simplicity of the hardware promote deployment scalability.</p>","PeriodicalId":10500,"journal":{"name":"Cognitive Neurodynamics","volume":"20 1","pages":"17"},"PeriodicalIF":3.9,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12681505/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145707485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信
小红书