Clinical Oral Investigations最新文献

{"title":"Streptococcus mutans serotyping, collagen-binding genes and Candida albicans in dentin carious lesions: a molecular approach.","authors":"Wanessa Fernandes Matias Regis, Francisco Wilker Mustafa Gomes Muniz, Francisco Ruliglésio Rocha, Ernanda Maria de Araújo Sales, Pedro Henrique Acioly Guedes Peixoto Vieira, Myrna Maria Arcanjo Frota Barros, Stephanie de Almeida Alves, Raimunda Sâmia Nogueira Brilhante, Simone Duarte, Beatriz Gonçalves Neves, Lidiany Karla Azevedo Rodrigues","doi":"10.1007/s00784-024-06140-0","DOIUrl":"10.1007/s00784-024-06140-0","url":null,"abstract":"<p><strong>Objectives: </strong>This cross-sectional study aimed to evaluate the occurrence of Streptococcus spp., Streptococcus mutans, its serotypes (c, e, f, and k), collagen-binding genes (cnm/cbm), and Candida albicans in medium deep (D2) and deep (D3) dentin carious lesions of permanent teeth.</p><p><strong>Materials and methods: </strong>Carious dentin was collected from D2 (n = 23) and D3 (n = 24) lesions in posterior teeth from 31 individuals. DNA was extracted and analyzed using polymerase chain reaction (PCR).</p><p><strong>Results: </strong>Streptococcus spp. exhibited a high prevalence in both D2 and D3 lesions, with a 100% occurrence rate in D3. Although S. mutans was prevalent in both lesion types, serotype distribution highlighted differences in complexity. Serotype e was the most frequently detected in D2 samples. Serotype c was absent in D2 but present in 19.0% of D3; serotype k was exclusively found in multi-serotype D3 alongside f, c, and e. The cbm gene and undetermined serotypes were detected only in D3. Candida albicans was not found in any samples, regardless of lesion depth.</p><p><strong>Conclusion: </strong>Dentinal lesions exhibited a complex array of S. mutans serotypes, with a notable prevalence of the genus Streptococcus and an overall S. mutans prevalence of approximately 35%. Candida albicans was absent. In addition, a high diversity of serotypes was observed, including multiple and indeterminate serotypes, along with the presence of the collagen-binding cbm gene.</p><p><strong>Clinical relevance: </strong>The identification of diverse Streptococcus mutans serotypes and the cbm gene in carious dentin from permanent teeth offers insights into microbial factors potentially linked to dentinal caries lesions. Additionally, the absence of Candida albicans suggests a limited role in this context.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 1","pages":"52"},"PeriodicalIF":3.1,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142945925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The plaque reducing efficacy of oil pulling with sesame oil: a randomized-controlled clinical study.","authors":"Christine Zürcher, Kristian Vukoje, Eva Maria Kleiner, Sophie Martina Kuster, Lisa Katharina Jäger-Larcher, Ingrid Heller, Sigrun Eick, Markus Nagl, Ines Kapferer-Seebacher","doi":"10.1007/s00784-024-06134-y","DOIUrl":"10.1007/s00784-024-06134-y","url":null,"abstract":"<p><strong>Objectives: </strong>To compare the plaque reducing efficacy of oil pulling with sesame oil compared to distilled water in a randomized, controlled, examiner-blinded parallel group study.</p><p><strong>Materials and methods: </strong>Forty probands without advanced periodontal disease of the University Hospital for Restorative Dentistry and Periodontology, Medical University of Innsbruck (Austria) were randomized allocated to test- (sesame oil) or control group (distilled water) and asked to pull daily in the morning for eight weeks with their allotted fluid for 15 min. Rustogi Modified Navy Plaque Index (RMNPI) and gingival bleeding index were assessed at baseline and after four and eight weeks. Plaque samples underwent microbiological analysis.</p><p><strong>Results: </strong>Pulling with sesame oil was significantly more effective in reducing full mouth RMNPI compared to distilled water after eight weeks (median reduction 18.98% versus 10.49%; p = 0.023), and was most pronounced in anterior, buccal, and lingual subscales. On approximal surfaces, significantly higher plaque reduction was found in the test group after four (24.07% versus 14.29%) and eight weeks (16.00% versus 5.36%) of intervention (p < 0.05). No significant changes in gingival index and mirobiological analysis could be detected.</p><p><strong>Conclusion: </strong>Plaque reduction was statistically significantly higher with oil pulling than with distilled water, however, a study bias cannot be ruled out. Further high-quality trials are needed to understand the mechanisms and effectiveness of oil pulling, to finally clarify the evidence.</p><p><strong>Clinical relevance: </strong>Oil pulling may be recommended as an adjuvant to mechanical dental cleaning. Individuals with keratosis may experience adverse effects.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov NCT06327841.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 1","pages":"53"},"PeriodicalIF":3.1,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11717832/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142945927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Two experimental methods to integrate intra-oral scans into 3D stereophotogrammetric facial images.","authors":"Reinout R P Schobben, Frits A Rangel, Robin Bruggink, Marjolein L D Crins-de Koning, Ewald M Bronkhorst, Edwin M Ongkosuwito","doi":"10.1007/s00784-024-06138-8","DOIUrl":"10.1007/s00784-024-06138-8","url":null,"abstract":"<p><strong>Objectives: </strong>For this research two different ways for integrating intra-oral scans into three-dimensional (3D) stereophotogrammetric images are analyzed and compared to the gold standard method.</p><p><strong>Materials and methods: </strong>A cross-sectional study was performed. For each patient a complete dataset was collected, which was used to generate 3D fusion models by three different methods: method A using cheek retractors, method B using a tracer and method C using full-skull CBCT. The experimental methods A and B were compared to the gold standard method C.</p><p><strong>Results: </strong>A group of eighteen patients were included in this study. The translation (X, Y,Z), the euclidean distance and the rotation (roll, pitch, yaw) were calculated for both experimental methods A and B in comparison with the gold standard method C. Twelve out of fourteen measurements were clinically acceptable (below 2 mm or 2 degrees). Method A shows the highest deviation in the pitch-orientation for rotation (2.51 degrees, 95% CI [1.756 … 3.272]), while method B shows a higher deviation along the y-axis (1.85 mm, 95% CI [1.224 … 2.467]).</p><p><strong>Conclusions: </strong>This study shows promising results of non-ionizing methods to integrate intra-oral scans into 3D stereophotogrammetric images. With improved accuracy in pitch in method A and translation along the Y-axis in method B, all measurements will be within the clinically acceptable threshold. However, since these two measurements exceed the clinically acceptable thresholds, the complete model positioning is less accurate. Therefore the main goal in further research should be to improve the accuracy of the pitch in method A and the translation along the Y-axis in method B. Additionally, for clinical use the biggest improvement could be gained by optimizing the clinical workflow and data processing.</p><p><strong>Clinical relevance: </strong>By using a non-ionizing 3D fusion model instead of a conventional cephalogram for treatment planning, the ionizing dose during orthodontic treatment can be significantly reduced.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 1","pages":"54"},"PeriodicalIF":3.1,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11717827/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142945245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fracture load of feldspar ceramic crowns: effects of surface treatments and aging.","authors":"Andrea Coldea, Bogna Stawarczyk, John Meinen, Valerie Lankes, Michael V Swain, Malgorzata Roos","doi":"10.1007/s00784-024-06144-w","DOIUrl":"10.1007/s00784-024-06144-w","url":null,"abstract":"<p><strong>Objectives: </strong>To compare the impact of intaglio surface treatments - airborne particle abrasion and hydrofluoric acid (HF) etching - of feldspar ceramic (FEL) crowns on the fracture load (FL) and to investigate the effects of abutment materials and artificial aging. The aim was to assess whether etching could be replaced by an alternative surface roughening method.</p><p><strong>Materials and methods: </strong>FEL crowns had their intaglio surfaces either abraded (25 µm Al₂O₃, 0.1 MPa), etched (HF, 60 s), or untreated and then bonded to CoCrMo- and polymer-abutments. FL was measured for non-aged and aged (1.2 million mastication cycles) specimens. Data were analyzed using, Weibull modulus, two-/one-way ANOVA with Tukey HSD-post-hoc-test, t-tests, and TOST equivalence (p < 0.05).</p><p><strong>Results: </strong>For crowns bonded to CoCrMo abutments, aging affected the FL and Weibull modulus, but pretreatment methods did not. For initial specimens, airborne abraded and etched crowns were equivalent within a 400N bound, however, for aged specimens, equivalence was inconclusive. For crowns bonded to polymer-abutments, pretreatment and aging influenced the FL. Etching decreased the initial FL by over 420N compared to airborne abraded and untreated specimens. After aging, untreated crowns' FL decreased by 528N, while airborne abraded and etched specimens showed no aging effect.</p><p><strong>Conclusions: </strong>Airborne particle abrasion of FEL crowns' intaglio surfaces did not negatively impact FL and was comparable to etched crowns. Conclusions regarding pretreatment methods and aging differed between CoCrMo- and polymer-abutments.</p><p><strong>Clinical relevance: </strong>Airborne particle abrasion may be an alternative procedure for the intaglio surface treatment of FEL crowns prior bonding.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 1","pages":"51"},"PeriodicalIF":3.1,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11711631/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142945924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and patient-reported outcomes between full-endoscopic and conventional parotidectomy: a prospective cohort study.","authors":"Su Chen, Yun-Cong Huang, Ze-Kang Su, Fan Yang, Grace Paka Lubamba, Anand Gupta, Khaled Alkebsi, Zhi-Yan Zhang, Zhuang Zhang, Hui Xia, Yong-Qing Zhang, Chun-Jie Li, Ming Xuan, Xiu-Fa Tang, Gui-Quan Zhu","doi":"10.1007/s00784-024-06118-y","DOIUrl":"https://doi.org/10.1007/s00784-024-06118-y","url":null,"abstract":"<p><strong>Objectives: </strong>This study investigates the clinical and patient-reported outcomes of full-endoscopic parotidectomy compared to the conventional approach.</p><p><strong>Methods: </strong>Between July 2021 and December 2023, patients who underwent parotidectomy were prospectively enrolled and assigned to either the full-endoscopic parotidectomy group (Group I) or the conventional surgery group (Group II). Clinical outcomes were evaluated, and patient-reported outcomes were assessed using a Visual Analogue Scale and five FACE-Q scales.</p><p><strong>Results: </strong>A total of 293 patients were prospectively included, with 146 in the full-endoscopic group and 147 in the conventional group. Blood loss was significantly lower in the full-endoscopic group (regression coefficient, 0.61; 95% CI, 0.15 to 1.07), as was the rate of immediate facial paralysis (0.76; 95% CI, 0.25 to 1.27). The full-endoscopic group also showed superior outcomes on the Visual Analogue Scale (- 0.14; 95% CI, - 0.23 to - 0.05) and FACE-Q scales for Appearance-Related Psychosocial Distress (1.15; 95% CI, 0.59 to 1.71), Social Function (- 0.37; 95% CI, - 0.59 to - 0.15), Satisfaction with Facial Appearance (- 0.44; 95% CI, - 0.64 to - 0.23), Psychological Function (- 0.39; 95% CI, - 0.58 to - 0.20), and Satisfaction With Outcome (- 0.42; 95% CI, - 0.66 to - 0.19).</p><p><strong>Conclusions: </strong>Full-endoscopic parotidectomy yields less blood loss and a reduced incidence of immediate facial paralysis compared to conventional surgery. Patients undergoing full-endoscopic parotidectomy reported better aesthetic and psychological outcomes.</p><p><strong>Clinical relevance: </strong>The combined analysis of clinical and patient-reported outcomes is valuable in guiding surgical planning. These findings provide valuable insights for patients considering full-endoscopic parotidectomy and underscore the importance of addressing functional, aesthetic, and psychological aspects for both patients and healthcare providers.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 1","pages":"49"},"PeriodicalIF":3.1,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143255020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The clinical performance of high-viscosity glass ionomer-based and bulk-fill resin-based restorations in permanent teeth with occlusal or proximal cavities: a systematic review and meta-analysis.","authors":"Xinyue Huang, Ruonan Zhang, Xueqian Yu, Wenting Sun, Lu Zhang, Fang Hua, Zhi Chen","doi":"10.1007/s00784-024-06127-x","DOIUrl":"10.1007/s00784-024-06127-x","url":null,"abstract":"<p><strong>Objectives: </strong>To summarize and analyze existing evidence regarding the clinical performance of high-viscosity glass-ionomer-based materials (HVGIs) and bulk-fill resin-based composites (BFs) in patients with occlusal or proximal cavities in permanent teeth.</p><p><strong>Materials and methods: </strong>A literature search was conducted using PubMed, Cochrane Central Register of Controlled Trials (CENTRAL), Embase, Scopus, and Web of Science (WOS) (last update: April 19th, 2024). Randomized control trials (RCTs), retrospective and prospective comparative cohorts were included. Manual searching was performed for twelve relevant dental journals. The primary outcome was the retention of the restoration. The evaluation of included studies, data extraction, and study selection were completed by two independent reviewers. The Cochrane risk-of-bias tool (RoB 2) and the Newcastle-Ottawa scale were used to assess the quality of included studies. A quantitative meta-analysis was conducted, and the overall quality of the evidence was evaluated.</p><p><strong>Results: </strong>Five RCTs and one retrospective study were included, of which one had a high risk of bias and the others had an unclear risk of bias. In meta-analyses, HVGIs were associated with a less favorable outcome on retention both at one (p = 0.013) and two-year follow-ups (p < 0.0001) compared with BFs. The quality of the evidence was very low.</p><p><strong>Conclusions: </strong>Very low certainty evidence suggested that BFs presented favorable clinical performance on retention and marginal adaptation in Class I and II restorations in permanent teeth comparing HVGIs. Nevertheless, HVGIs with a resin-based coating showed acceptable clinical behavior.</p><p><strong>Clinical relevance: </strong>For patients with a high caries risk, HVGIs serve as a direct restorative alternative for the posterior permanent teeth; however, they should be carefully considered as bulk-fill composite resin alternatives for long-term restoration.</p><p><strong>Registration: </strong>PROSPERO (CRD42024535999).</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 1","pages":"50"},"PeriodicalIF":3.1,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142962133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Approaches to regenerative endodontic therapy in necrotic human teeth with complete root formation: a systematic review.","authors":"Rafaela Hartmann Kasper, Kathleen Sobieray Schneider, Myrian Camara Brew, José Antonio Poli Figueiredo, Fernando Branco Barletta","doi":"10.1007/s00784-024-06137-9","DOIUrl":"10.1007/s00784-024-06137-9","url":null,"abstract":"<p><strong>Introduction: </strong>Regenerative endodontic procedures (REPs) aim to replace damaged dental structures and regenerate the dentin-pulp complex. Initially focused on teeth with incomplete root formation, recent research shows promise for necrotic teeth with complete root formation.</p><p><strong>Methodology: </strong>This review, following PRISMA guidelines and registered in PROSPERO, included clinical studies on regenerative endodontic therapy in necrotic human teeth with complete root formation. Searches in PubMed, Web of Science, Embase, and Cochrane Library identified 10 studies meeting the criteria.</p><p><strong>Results: </strong>The studies showed variable regenerative endodontic protocols and materials, with success rates ranging from 60 to 100%. Most studies reported favorable outcomes, such as symptom resolution and bone healing.</p><p><strong>Discussion: </strong>Regenerative endodontic therapy for necrotic teeth with complete root formation shows high success rates, but the variability in protocols calls for standardized guidelines and further high-quality trials.</p><p><strong>Conclusion: </strong>Regenerative endodontic therapy is a promising alternative to conventional treatments for necrotic teeth with complete root formation, with demonstrated potential for restoring pulp vitality.Future research should optimize protocols and materials for consistent success.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 1","pages":"45"},"PeriodicalIF":3.1,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142930465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dental arch dimensional changes in deep bite adults treated with orthodontic fixed appliances in conjunction with maxillary incisor vs. canine bite turbos during the levelling and aligning phase: a randomized clinical trial.","authors":"Puttaporn Supanich, Udom Thongudomporn, Smorntree Viteporn","doi":"10.1007/s00784-024-06145-9","DOIUrl":"10.1007/s00784-024-06145-9","url":null,"abstract":"<p><strong>Introduction: </strong>This randomized clinical trial compared arch dimensional changes, dentoskeletal changes, and the rate of overbite correction in deep bite adults treated with fixed appliances and either maxillary incisor bite turbos (IBT) or canine bite turbos (CBT).</p><p><strong>Materials and methods: </strong>Forty-six deep bite subjects treated with fixed appliances were randomized into IBT (n = 23) and CBT (n = 23) groups. Changes in intercanine width (ICW), arch height (AH), and Little's Irregularity Index (LII) were analyzed from before treatment (T₀) to 3 months after aligning with 0.012\" NiTi archwires in both arches (T₁). Cephalometric changes between T₀ and the visit when normal overbite was achieved (T₂) were assessed. Within-group and between-group comparisons were analyzed at a significance level of 0.05.</p><p><strong>Results: </strong>In both groups, mandibular ICW, and maxillary and mandibular AH significantly increased while maxillary and mandibular LII decreased. Maxillary and mandibular incisor proclination and molar extrusion were observed. The IBT group showed significantly greater changes in mandibular ICW, maxillary and mandibular AH, and mandibular incisor proclination than the CBT group. However, the overbite correction rate and the LII reduction were not significantly different between the groups.</p><p><strong>Conclusions: </strong>The IBT and CBT produced similar effects on arch dimensions and dentoskeletal changes. However, the IBT group demonstrated greater arch dimensional changes.</p><p><strong>Clinical relevance: </strong>Clinicians may consider IBT if flaring incisors is desired. Alternatively, CBT is better for cases with limited incisor proclination and where minimizing arch dimension change is needed, such as in narrow ridge situations.</p><p><strong>Clinical trial registration: </strong>The trial was registered at Thai Clinical Trial Registry on https://www.thaiclinicaltrials.org , under the identifier TCTR20230811013.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 1","pages":"46"},"PeriodicalIF":3.1,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142930538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of post-processing on the surface, optical, mechanical, and dimensional properties of 3D-printed orthodontic clear retainers.","authors":"Siew Peng Neoh, Anak Khantachawana, Peerapong Santiwong, Rochaya Chintavalakorn, Toemsak Srikhirin","doi":"10.1007/s00784-024-06120-4","DOIUrl":"10.1007/s00784-024-06120-4","url":null,"abstract":"<p><strong>Objectives: </strong>To address the high surface roughness and poor optical properties of three-dimensional (3D) printed orthodontic clear retainers, an alternative post-processing protocol was investigated with the goal of achieving improved surface, optical, and mechanical properties while preserving dimensional accuracy.</p><p><strong>Materials and methods: </strong>Samples were prepared from two biocompatible methacrylate-based 3D-printing resins (Formlabs Dental LT Clear V2, NextDent OrthoFlex) and one thermoplastic material (Duran). For the 3D-printed resins, one group was post-processed by rinsing in isopropyl alcohol, while another group was centrifuged before post-curing in glycerine. Three different testing conditions were used: dry, wet (24-h water immersion), and aged (thermocycling for 10,000 cycles). Surface characteristics were evaluated qualitatively and quantitatively. Optical properties were assessed for transparency and colour stability, while mechanical properties were elicited from tensile and microhardness tests. Water sorption and solubility were calculated. Samples mounted on a dental model were scanned by micro-computed tomography to measure thickness and gap width.</p><p><strong>Results: </strong>3D-printed samples post-processed by centrifugation showed significantly decreased surface roughness and improved visible light transmission, colour stability, tensile strength, and hardness. The centrifuged samples showed significantly increased thickness, while designing an offset equal to this thickness improved the adaptation.</p><p><strong>Conclusions: </strong>Post-processing by centrifugation produces surface coating that enhances the surface and optical properties of the 3D-printed orthodontic retainers, while curing in an oxygen-free environment improves their mechanical properties. Design modifications may be necessary for this protocol to ensure proper adaptation to the dentition.</p><p><strong>Clinical relevance: </strong>Proper design and post-processing protocols are necessary to achieve the desired properties of orthodontic clear retainers.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 1","pages":"48"},"PeriodicalIF":3.1,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11703938/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142930541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral health and rehabilitation in face transplant recipients - a systematic review.","authors":"Leonard Knoedler, Martin Kauke-Navarro, Samuel Knoedler, Tobias Niederegger, Elena Hofmann, Max Heiland, Steffen Koerdt, Susanne Nahles, Helena Baecher","doi":"10.1007/s00784-024-06078-3","DOIUrl":"10.1007/s00784-024-06078-3","url":null,"abstract":"<p><strong>Background: </strong>Facial transplantation (FT) provides advanced solutions for severe facial defects by incorporating complex tissues such as bone, skin, oral mucosa and nerves. Oral health plays a critical role in FT, impacting both functional outcomes and transplant prognosis. Despite its importance, literature on oral health in FT recipients remains sparse.</p><p><strong>Methods: </strong>This systematic review adhered to PRISMA guidelines. We searched PubMed, EMBASE, Web of Science, and CENTRAL for studies on oral health in FT patients up to August 4, 2024. Eligible studies were evaluated using the Newcastle-Ottawa Scale (NOS) and Level of Evidence (LOE). Data extracted included study design, general information on FT, patient demographics, oral examination techniques, and outcomes.</p><p><strong>Results: </strong>Out of 6,984 articles reviewed, 19 met the inclusion criteria, all consisting of case reports or case series involving 48 FT cases. Of these, 25 cases provided relevant oral health and rehabilitation data. All studies showed a LOE of IV, with an average NOS score of 4.3 ± 0.5. Most FT cases involved male recipients (n = 20, 80%), while the majority of FTs were conducted in the United States (n = 10, 40%) and France (n = 7, 28%). Oral mucosa biopsy was the most common examination method (n = 11, 44%). Malocclusion was reported in 48% (n = 12) of cases, with revision surgeries occurring in 36% (n = 9). Post-FT dental treatments included tooth extractions (n = 7, 28%), fillings (n = 3, 12%), and endodontic treatments (n = 2, 8%). Dental implants were placed in 32% (n = 8) of cases, with one case (4%) reporting failed osseointegration.</p><p><strong>Conclusion: </strong>Routine oral health assessments are essential for FT patients to prevent complications and improve clinical outcomes. However, there is a lack of high-quality research on oral health in FT recipients, underscoring the need for further studies to establish standardized care protocols.</p><p><strong>Clinical relevance: </strong>This review emphasizes the urgent need for standardized oral health protocols in FT patients to minimize infection risks and optimize long-term transplant success and overall patient health.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 1","pages":"47"},"PeriodicalIF":3.1,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11703954/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142930543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}