Clinical Oral Investigations最新文献

{"title":"Assessing the accuracy, repeatability, and consistency of ChatGPT 4o in treatment planning for tooth-supported fixed prostheses: a comparative analysis of simple and complex clinical cases.","authors":"Özer İşisağ, Kevser Karakaya","doi":"10.1007/s00784-025-06521-z","DOIUrl":"10.1007/s00784-025-06521-z","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of this study is to evaluate the effectiveness of ChatGPT 4o in planning tooth-supported fixed prostheses by examining the accuracy, repeatability, and consistency of its responses across various prosthodontic cases.</p><p><strong>Materials and methods: </strong>1,140 responses were generated for 38 questions regarding simple and complex prosthetic cases, using case schemas from Fundamentals of Fixed Prosthodontics. Each question was asked 30 times at different times of day (morning, afternoon, and evening) to assess response consistency.</p><p><strong>Results: </strong>ChatGPT demonstrated high accuracy (97.08%) for simple fixed prostheses but struggled with complex cases, showing a low accuracy rate of 19.69%. Statistically significant differences were observed in the response accuracy between question categories, indicating that ChatGPT performs better with straightforward cases than with complex ones. Repeatability was high across all question types, though accuracy varied, especially in complex scenarios.</p><p><strong>Conclusions: </strong>The findings highlight ChatGPT's potential as an assistive tool in simple prosthodontic cases yet emphasize the need for clinician expertise in more complex treatment planning.</p><p><strong>Clinical relevance: </strong>While ChatGPT shows promise as a supplementary tool for dental education and practice, reliance on AI alone for intricate cases remains premature.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 9","pages":"433"},"PeriodicalIF":3.1,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144945434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Space closure after premolar extraction using clear aligners: a systematic review with meta-analysis.","authors":"Fernanda Vicioni-Marques, Caio Luiz Bitencourt Reis, Ana Paula Valladares de Almeida, Letícia Pinho Maia Paixão de Melo, Fábio Lourenço Romano, Mirian Aiko Nakane Matsumoto, Maria Bernadete Sasso Stuani","doi":"10.1007/s00784-025-06475-2","DOIUrl":"10.1007/s00784-025-06475-2","url":null,"abstract":"<p><strong>Background: </strong>The efficacy of clear aligner treatment (CAT) in space closure following premolar extraction (SCaPE) and its resistance to unwanted tooth movement remain uncertain. This systematic review aims to evaluate the efficacy, predictability, and resistance to unwanted tooth movement by CAT for SCaPE.</p><p><strong>Methods: </strong>Pre-post studies, randomized, and non-randomized clinical trials were included. A comprehensive search was conducted in PubMed, Scopus, Embase, Web of Science, and Cochrane Library databases up to November 12, 2024. Study quality was assessed using ROB-2 and ROBINS-I tools. Three independent reviewers performed data extraction. A meta-analysis compared predicted versus achieved maxillary tooth movements in similar studies using the Invisalign^® system. Standardized Paired Difference (SPD) with 95% Prediction Interval (95% PI) and Confidence Interval (95% CI) were used for effect size estimation. The GRADE tool evaluated the certainty of evidence.</p><p><strong>Results: </strong>Fourteen studies encompassing 510 participants were included. Four studies had a low risk of bias, while ten had a high risk of bias. The results from pre-post studies indicated that CAT was significantly less effective than predicted in achieving Anterior Teeth Retraction (SPD= -0.87; 95% CI = -1.15 to -0.60; 95% PI= -1.14 to -0.59; p < 0.001; number of studies = 4), resulting in more lingual tipping (SPD = 1.09; 95% CI = 0.46 to 1.73; 95% PI= -1.01 to 3.19; p = 0.001; number of studies = 3) and extrusion of anterior teeth (SPD = 0.88, 95% CI = 0.47 to 1.29; 95% PI= -0.16 to 1.92; p < 0.001; number of studies = 4) than predicted. The achieved distal tipping of canine (SPD = 1.42; 95% CI = 0.35 to 2.51; 95% PI= -2.5 to 5.40; p = 0.009; number of studies = 3) and mesial tipping of first molars (SPD = 1.68; 95% CI = 1.17 to 2.20; 95% PI = 0.34 to 3.01; p < 0.001; number of studies = 3;) were also greater than predicted. Clinical trials comparing CAT and fixed appliances provide limited evidence.</p><p><strong>Conclusion: </strong>The findings suggest that CAT may not be effective or predictable for SCaPE due to its limited capacity to promote the bodily movement of the teeth and control anchorage. Evidence indicates that fixed appliances might be superior to CAT. Limitations of the evidence include bias across studies, with the certainty of evidence ranging from low to very low. Future research should focus on improving prediction models and exploring the potential benefits of accessories to enhance CAT's effectiveness.</p><p><strong>Registration: </strong>Not registered.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 9","pages":"435"},"PeriodicalIF":3.1,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144945356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differentiation of benign and malignant oral lesions through surface texture analysis and SVM modeling.","authors":"Barış Oğuz Gürses, Nezaket Ezgi Özer, Gaye Bölükbaşı, Betul İlhan, Adar Gözen, Hayal Boyacıoğlu, Pelin Güneri","doi":"10.1007/s00784-025-06478-z","DOIUrl":"10.1007/s00784-025-06478-z","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the diagnostic potential of surface texture features extracted from clinical images in objectively differentiating benign from malignant oral lesions, and to validate classification performance of a Support Vector Machine (SVM) model using these features.</p><p><strong>Materials and methods: </strong>This study included 275 intraoral photographs of oral mucosal lesions with biopsy-confirmed diagnoses, sourced from both institutional archives and a public dataset. Lesion areas were manually annotated and converted into 3D surface plots to extract grayscale-based texture features. Eight statistical descriptors-mean, mode, median, variance, skewness, kurtosis, coefficient of variation (CoV), and entropy-were computed and normalized relative to adjacent healthy mucosa. Group differences were analyzed using MANOVA and effect size metrics (Cohen's d, eta squared). A support vector machine (SVM) with a Gaussian kernel was trained using five-fold cross-validation to classify lesions as benign or malignant based on the extracted features.</p><p><strong>Results: </strong>Statistical analysis revealed significant differences between benign and malignant groups for all features except skewness (p < 0.001). Entropy, kurtosis, and CoV showed the largest effect sizes, with entropy notably higher in malignant lesions and kurtosis higher in benign ones. The SVM model achieved a sensitivity of 99.2%, specificity of 81.4%, overall accuracy of 90.5%, and an AUC of 0.939, demonstrating high diagnostic performance in distinguishing malignant from benign oral mucosal lesions based on surface texture analysis.</p><p><strong>Conclusions: </strong>Surface texture features, particularly entropy and kurtosis, offer promising diagnostic indicators for distinguishing malignant from benign lesions. SVM classifier demonstrated robust performance using these parameters.</p><p><strong>Clinical relevance: </strong>This study highlights surface texture as an objective, underexplored diagnostic parameter. Integrating surface topography into clinical assessments and AI-based tools may enhance early detection and diagnostic accuracy in oral cancer screening.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 9","pages":"431"},"PeriodicalIF":3.1,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144945415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparative assessment of orthodontically induced root resorption and alveolar bone changes in adolescent orthodontic patients undergoing Micro-Osteoperforations assisted canine retraction: A Split-Mouth randomized controlled trial.","authors":"Deepanshi Yadav, Puneet Batra, Aditya Talwar, Saurabh Sonar, Amit Srivastava","doi":"10.1007/s00784-025-06507-x","DOIUrl":"10.1007/s00784-025-06507-x","url":null,"abstract":"<p><strong>Introduction: </strong>Micro-osteoperforation (MOP) is a minimally invasive technique aimed at accelerating orthodontic tooth movement (OTM) by stimulating localised bone remodelling. However, its impact on root resorption, alveolar bone levels, and inflammatory mediators such as interleukin-4 (IL-4) requires further investigation. This study assessed root resorption, alveolar bone changes, canine angulation, rate of retraction, and IL-4 expression associated with MOP-assisted canine retraction.</p><p><strong>Methods: </strong>A randomised split-mouth controlled clinical trial was conducted on 20 patients (mean age: 19.70 ± 2.38 years). Patients were randomised according to the SNOSE criteria, with one side receiving MOPs distal to the canine; the contralateral side served as control for both maxillary and mandibular dentition. Retraction was performed using 9 mm NiTi closed coil springs with 150 g force for 7.6 ± 1.2 months. Pre- and post-retraction CBCT scans evaluated linear root resorption and alveolar bone changes. Digital models assessed canine movement and angulation. Gingival crevicular fluid was collected at four intervals and analyzed for IL-4 using ELISA.</p><p><strong>Results: </strong>Maxillary and mandibular canines showed relatively greater root resorption (1.03 mm and 0.57 mm, respectively) and crestal bone loss (0.893 mm and 0.56 mm, respectively) on the MOP side (p < 0.05). The rate of canine retraction was higher with MOP (maxilla: 1.28 ± 0.17 mm/month; mandible: 1.36 ± 0.16 mm/month) compared to control (p < 0.001) with increased canine tipping noted on MOP side. IL-4 levels showed a transient decline post-MOP, recovering by day 28.</p><p><strong>Conclusions: </strong>MOP effectively accelerates OTM but increases the risk of root and alveolar bone resorption. The associated reduction in IL-4 may contribute to enhanced osteoclastic activity. Clinical application should be case-dependent, with caution in patients at risk of periodontal or root compromise.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 9","pages":"429"},"PeriodicalIF":3.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144945420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of surface treatment on roughness, fracture force, flexural strength, and dynamic loading of a 3D-printed crown and bridge material.","authors":"Michael Benno Schmidt, Sebastian Hahnel, Angelika Rauch, Martin Rosentritt","doi":"10.1007/s00784-025-06518-8","DOIUrl":"10.1007/s00784-025-06518-8","url":null,"abstract":"<p><strong>Objectives: </strong>To investigate how surface treatment affects fracture force, flexural strength, and dynamic loading cycles until failure of 3D-printed restorations.</p><p><strong>Materials and methods: </strong>Specimens (7 groups; n = 8 per group) were 3D-printed from an acrylate-based crown and bridge material. After cleaning and post-polymerization, specimens were treated with either silicon carbide paper (1000 grit; 1000/4000 grit) or blasting (Al₂O₃; 1 bar/125 µm; 2 bar/125 µm; 1 bar/250 µm) to simulate laboratory treatment. Surface roughness (Arithmetic mean Sa/maximum roughness height Sz; ISO 25178-2); fracture force (FF) and biaxial flexural strength (BFS; ISO 6872) were determined. The number of dynamic load cycles (LC) to failure was determined under cyclic loading in a BFS staircase approach.</p><p><strong>Statistics: </strong>ANOVA, Bonferroni-test, Kaplan-Meier survival, Pearson correlation; α = 0.05.</p><p><strong>Results: </strong>BFS ranged between 94.4 MPa and 199.9 MPa, FF between 260.6 N and 428.6 N and Sa/Sz between 0.0/1.0 μm and 1.8/18.4 μm. BFS, FF and Sa/Sz showed significant differences between the treatments (p < 0.001) and individual groups (p ≤ 0.013). Mean LC ranged between 204,364 and 267,637 cycles. ANOVA comparisons (p = 0.706) and Log Rank test (Chi²: 10,835; p = 0.094; Fig. 2) revealed no significant differences between the loading cycles. Surface treatment with either silicon carbide papers or blasting protocols had a significant influence on FF, BFS, Sa, and Sz, but not on LC.</p><p><strong>Conclusions: </strong>Surface treatment affected the fracture force and biaxial fracture strength of a 3D-printed crown. It showed no influence on the long-term dynamic behavior.</p><p><strong>Clinical relevance: </strong>Smooth surfaces improve the stability of a restoration fabricated from 3D-printing resins. Extensive surface roughness treatment before cementation can reduce the stability of a crown.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 9","pages":"426"},"PeriodicalIF":3.1,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12398470/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144945364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: Combined catalytic strategies applied to in-office tooth bleaching: whitening efficacy, cytotoxicity, and gene expression of human dental pulp cells in a 3D culture model.","authors":"Rafael Antonio de Oliveira Ribeiro, Victória Peruchi, Igor Paulino Mendes Soares, Filipe Koon Wu Mon, Diana Gabriela Soares, Josimeri Hebling, Carlos Alberto de Souza Costa","doi":"10.1007/s00784-025-06530-y","DOIUrl":"10.1007/s00784-025-06530-y","url":null,"abstract":"","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 9","pages":"427"},"PeriodicalIF":3.1,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144945432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of systemic resveratrol on non-surgical periodontal treatment of smokers: A 12-month randomized clinical trial.","authors":"Vanessa Haguihara Lucchesi, Ana Paula Oliveira Giorgetti, Mônica Grazieli Corrêa, Vanessa G A Pecorari, Bruno Braga Benatti, Howard C Tenenbaum, Fabiano Ribeiro Cirano, Suzana Peres Pimentel, Márcio Zafallon Casati","doi":"10.1007/s00784-025-06517-9","DOIUrl":"10.1007/s00784-025-06517-9","url":null,"abstract":"<p><strong>Objective: </strong>Smoking patients demonstrate an elevated risk of periodontitis development and respond poorly to periodontal therapy as compared to nonsmokers, and resveratrol (RSV) demonstrated a positive effect in the reduction of periodontitis progression in both animal and clinical trials. However, to the authors' knowledge, no clinical study has assessed the impact of resveratrol under smoking conditions. Thus, this trial aimed to evaluate the effect of systemic administration (SA) of RSV adjunct to full-mouth ultrasonic debridement (FMUD) of periodontitis smoking patients (PSP).</p><p><strong>Materials and methods: </strong>Thirty-eight individuals were randomly assigned to two groups:Placebo ( n = 19) -FMUD and placebo for 180 days; RSV ( n = 19) FMUD and RSV (500 mg/day) for 180 days. Clinical and immunoinflammatory outcomes were assessed at baseline, 3-, 6-, and 12-months post-therapy, and microbiological outcomes were evaluated at baseline, 3-, 6- months post-therapy.</p><p><strong>Results: </strong>RSV appeared to induce lower PD [2.96 (0.41) - 3 months; 2.85 (0.40) - 6 months; 2.80 (0.35)- 12 months], CAL [4.02 (0.90) - 3 months; 4.04 (0.81) - 6 months; 3.87 (0.78) - 12 months], and PMG [2.20 (0.56) - 3 months; 2.28 (1.14) - 6 months; 2.32 (3.27) - 12 months] readings as compared to Placebo [PD: 3.22 (0.51) - 3 months; 3.07 (0.42) - 6 months; 3.02 (0.42) - 12 months; CAL: 4.43 (0.99) - 3 months; 4.24 ((0.89) - 6 months; 4.39 (0.93) - 12 months; PMG: 2.50 (0.50) - 3 months; 2.53 (0.45) - 6 months; 2.67 (0.46) - 12 months] throughout the time (p < 0.05). The concentration of Aggregatibacter actinomycetemcomitans (Aa) was significantly higher in moderate [2.29 (1.10); 1.61 (1.02) for PL and RSV, respectively] and deep PD [2.39 (1.14); 1.73 (0.90) for PL and RSV respectively] at 3 months for the Placebo group (p < 0.05). Additionally, Aa levels were lower at 6 months in the deep sites for the RSV group (p < 0.05) [1.77 (0.94); 2.23 (1.08) for PL and RSV, respectively]. Immunoinflammatory analysis showed lower levels of IL-1β at 3-month periods in deep sites in the RSV group [92.6 ± 84.2; 35.36 (52.92) for PL and RSV, respectively] and lower concentrations of IL-6 in the RSV group at 3 and 12 months in both moderate [8.11 (9.50); 4.67 (4.20) - 3 months for PL and RSV, respectively; 8.01 ± 3.52; 5.33 (4.14) - 12 months for PL and RSV, respectively]; and deep sites [4.69 (3.06); 3.57 (3.73) - 3 months for PL and RSV, respectively]; 3.50 (2.67); 2.10 (0.89) - 12 months for PL and RSV, respectively] (p < 0.05).</p><p><strong>Conclusion: </strong>In conclusion, systemic administration of RSV improves clinical results and modulates IL-1β at 3 months, IL-6 at 3- and 6- months, in deep sites of smoking patients when associated with FMUD.</p><p><strong>Trial registration: </strong>Rebec identifier https//ensaiosclinicos.gov.br/rg/RBR3gt65c.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 9","pages":"428"},"PeriodicalIF":3.1,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144945353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of maxillary occlusal splints on mobile posterior teeth in patients with stage III or IV periodontitis during steps 1 and 2 of periodontal therapy: a randomized parallel-controlled clinical trial.","authors":"Siyu Hui, Yilin Hong, Shuangshuang Chen, Yang Bao, Jia Song, Yuan Zhao, Xiaolin Tang","doi":"10.1007/s00784-025-06506-y","DOIUrl":"10.1007/s00784-025-06506-y","url":null,"abstract":"<p><strong>Aim: </strong>The present study aims to assess the efficacy of elastic occlusal splints on mobile posterior teeth in patients with stage III or IV periodontitis during Steps 1 and 2 of periodontal therapy.</p><p><strong>Materials and methods: </strong>Thirty-eight periodontitis patients, each with at least one mobile maxillary posterior tooth (mobility degree II or III), were randomly assigned to either the Splint group (n = 19), which received maxillary elastic occlusal splints, or the Control group (n = 19), without splints treatment. All patients received Steps 1 and 2 of periodontal therapy. Tooth mobility (TM), masticatory efficiency, probing depth (PD), evaluation of subjective comfort and other parameters were assessed at baseline (T0), 2 ~ 4 weeks (T1) and 6 ~ 8 weeks (T2) after the subgingival scaling. Masticatory efficiency was represented by optical density (OD). The subjective comfort score was recorded using a Visual Analogue Scale (VAS).</p><p><strong>Results: </strong>The value of OD in the Splint group was significantly greater than that in the Control group from T0 to T2 (0.19 ± 0.08 versus 0.09 ± 0.09, p < 0.05) and from T1 to T2 (0.11 ± 0.06 versus 0.02 ± 0.06, p < 0.05). Compared with the Control group, patients in the Splint group experienced significantly greater reduction in TM of mobile posterior teeth throughout each treatment period, as well as a more pronounced decrease in PD from T0 to T2. The score of VAS was 8.34 ± 1.10 at T1 and 8.52 ± 0.91 at T2 with elastic occlusal splints.</p><p><strong>Conclusion: </strong>The use of elastic occlusal splints as adjuncts during Steps 1 and 2 of periodontal therapy resulted in additional improvement of the masticatory efficiency of periodontitis patients, as well as the reduction of TM and PD of the mobile posterior teeth.</p><p><strong>Trial registration: </strong>ChiCTR2400090295.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 9","pages":"425"},"PeriodicalIF":3.1,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144944891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of charcoal-based dentifrices on the surface integrity and gloss of lithium disilicate glass-ceramics.","authors":"Victor Martins Stabile, Ana Caroline Lima Colombino, Andrey Gonçalves Emídio, Lourenço Correr-Sobrinho, Roberta Caroline Bruschi Alonso, Regina Maria Puppin-Rontani","doi":"10.1007/s00784-025-06494-z","DOIUrl":"10.1007/s00784-025-06494-z","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the effects of commercially charcoal-based dentifrices on the surface roughness and gloss retention of glazed lithium disilicate glass-ceramics subjected to simulated toothbrushing.</p><p><strong>Materials and methods: </strong>Seventy-two glazed lithium disilicate specimens (IPS e.max CAD) were randomly assigned to three dentifrice groups (n = 24): two charcoal-based (Carvvo (CVV), Curaprox Black is White (CBW)) and one conventional (Colgate Total 12 (C12)), the control. Toothbrushing simulations were performed for 5,000, 10,000, and 20,000 cycles. Roughness (Ra) and gloss (GU) were measured at baseline and after each cycle. Surface characterization was performed using three-dimensional profilometry and scanning electron microscopy (SEM), which also analyzed abrasive particles. Data were analyzed using two-way repeated measures ANOVA and Tukey's post-hoc test (α = 0.05).</p><p><strong>Results: </strong>Roughness was affected only by dentifrice type (p = 0.004), with CVV producing higher mean values than C12, and CBW not differing from the others. Brushing cycle (p = 0.164) and interaction (p = 0.095) were non-significant. Gloss was affected by dentifrice (p < 0.001), brushing cycle (p < 0.001), and their interaction (p < 0.001). Charcoal-based dentifrices caused gloss reductions (CVV: 80.77GU baseline to 67.41GU at 20,000 cycles; CBW: 86.39GU baseline to 69.62GU at 20,000 cycles). In contrast, C12 increased gloss, reaching up to 95.97GU at 20,000 cycles.</p><p><strong>Conclusions: </strong>Charcoal-based dentifrices significantly compromise the surface integrity of glazed lithium disilicate ceramics by increasing roughness and reducing gloss. Conventional dentifrices demonstrate no deleterious effect on ceramic surfaces and may even enhance gloss.</p><p><strong>Clinical relevance: </strong>Routine use of charcoal-based dentifrices may accelerate surface wear and reduce optical properties of ceramic restorations, potentially compromising longevity and esthetic outcomes.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 9","pages":"424"},"PeriodicalIF":3.1,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144945410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of ageing on surface properties and biofilm adhesion on denture base resin material fabricated by different manufacturing techniques.","authors":"Mirjana Perić, Sanja Petrović, Aleksandra Čairović, Tamara Vlajić Tovilović, Aleksandar Racić, Radmila Panajotović, Rade Živković, Biljana Miličić, Milena Radunović","doi":"10.1007/s00784-025-06488-x","DOIUrl":"10.1007/s00784-025-06488-x","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the effects of hydrothermal ageing on biofilm adhesion and surface properties of denture base resins fabricated via different techniques.</p><p><strong>Materials and methods: </strong>Denture base resin samples were produced using the following manufacturing techniques: conventional cold polymerization (CP), heat polymerization (HP), CAD-CAM milling (CADm) and CAD-CAM printing (3D). The samples were tested before and after hydrothermal ageing (5000 cycles, 5 °C/55°C). The surface roughness was measured using atomic force microscopy (AFM), and the hydrophobicity was observed by measuring the water contact angle (WCA). Monomicrobial biofilm of Staphylococcus aureus and Candida albicans were formed and quantified before and after ageing using colony-forming units (CFUs/ml) and the MTT test. Statistical differences were evaluated using a two-way analysis of variance (ANOVA).</p><p><strong>Results: </strong>Two-way ANOVA showed that ageing significantly influenced the roughness (p = 0.002). The highest roughness values before and after ageing were measured for 3D resin samples. The WCA values of 3D resin samples changed after ageing (p = 0.018). Amount and metabolic activity of monomicrobial biofilms were increased during ageing on all four tested denture base resins.</p><p><strong>Conclusions: </strong>Ageing influenced the roughness and microbial adhesion on all tested denture base materials, regardless of the manufacturing method.</p><p><strong>Clinical relevance: </strong>Finding support replacing dentures every five years due to increased biofilm adhesion post ageing.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 9","pages":"423"},"PeriodicalIF":3.1,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144945338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}