Clinical Oral Investigations最新文献

{"title":"Analysis of trends in the context of implant therapy in a university surgical specialty clinic: a 20-year retrospective study.","authors":"Clemens Raabe, Emilio Couso-Queiruga, Jennifer Tjokro, Daniel Buser, Michael M Bornstein, Manrique Fonseca, Frank Schwarz, Vivianne Chappuis","doi":"10.1007/s00784-024-06033-2","DOIUrl":"https://doi.org/10.1007/s00784-024-06033-2","url":null,"abstract":"<p><strong>Objectives: </strong>To analyze the trends in the context of implant therapy in a 3-year patient population and compare it with data obtained over the last 20 years.</p><p><strong>Materials and methods: </strong>All adult subjects who received treatment in the context of implant therapy between 2020 and 2022 were included in this retrospective study. Data regarding patient demographics, indications and location of implant therapy, implant characteristics, surgical techniques, complications, and early implant failures were recorded and compared to data obtained in the years 2002-2004, 2008-2010, and 2014-2016.</p><p><strong>Results: </strong>Between 2020 and 2022, n = 1555 implants were placed in n = 1021 patients. The mean age at implant placement was 59.9 + 15.1 years, demonstrating an increase over time in the age group 61-80 years of 23.1% and > 80 years of 3.2% (p < 0.0001). Single tooth gaps (48.9%) remained the main indication. The use of narrow diameters ≤ 3.5 mm increased (9.4% vs. 26.6%, p < 0.0001), while implant lengths > 10 mm decreased (45.7% vs. 23.5%, p < 0.0001). A reduction in more invasive techniques and an increase in computer-assisted implant surgeries (CAIS) of 19.5% was found.</p><p><strong>Conclusions: </strong>The mean age of patients receiving dental implant therapy, with the use of narrow-diameter and shorter implants has progressively increased in the last 20 years. The observed trends suggest a transition from conventional to CAIS, accompanied by the introduction of minimally invasive surgical techniques.</p><p><strong>Clinical relevance: </strong>The adoption of narrower and shorter implants, along with minimally invasive techniques and CAIS, enables clinicians to tailor treatment plans that accommodate the unique needs of aging patients and optimize clinical outcomes.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 1","pages":"27"},"PeriodicalIF":3.1,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142876322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Automated classification of pathological differentiation in head and neck squamous cell carcinoma using combined radiomics models from CET1WI and T2WI.","authors":"Yang Li, Wen Li, Haotian Xiao, Weizhong Chen, Jie Lu, Nengwen Huang, Qingling Li, Kangwei Zhou, Ikuho Kojima, Yiming Liu, Yanjing Ou","doi":"10.1007/s00784-024-06110-6","DOIUrl":"https://doi.org/10.1007/s00784-024-06110-6","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to develop an automated radiomics-based model to grade the pathological differentiation of head and neck squamous cell carcinoma (HNSCC) and to assess the influence of various magnetic resonance imaging (MRI) sequences on the model's performance.</p><p><strong>Materials and methods: </strong>We retrospectively analyzed MRI data from 256 patients across two medical centers, including both contrast-enhanced T1-weighted images (CET1WI) and T2-weighted images (T2WI). Regions of interest were delineated for radiomics feature extraction, followed by dimensionality reduction. An XGBoost classifier was then employed to build the predictive model, with its classification efficiency assessed using receiver operating characteristic curves and the area under the curve (AUC).</p><p><strong>Results: </strong>In validation cohort, the AUC (macro/micro) values for models utilizing CET1WI, T2WI, and the combination of CET1WI and T2WI were 0.801/0.814, 0.741/0.798, and 0.885/0.895, respectively. The AUC for the three differentiations, ranging from well-differentiated to poorly differentiated, were 0.867, 0.909, and 0.837, respectively. The macro/micro precision, recall, and F1 scores of 0.688/0.736, 0.744/0.828, and 0.685/0.779 for the CET1WI + T2WI model.</p><p><strong>Conclusion: </strong>This study demonstrates that constructing a radiomics model based on CET1WI and T2WI sequences can be used to predict the pathological differentiation grading of HNSCC patients.</p><p><strong>Clinical relevance: </strong>This study suggests that a radiomics model integrating CET1WI and T2WI MRI sequences can effectively predict the pathological differentiation of HNSCC, providing an alternative diagnostic approach through non-invasive preoperative methods.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 1","pages":"25"},"PeriodicalIF":3.1,"publicationDate":"2024-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142871603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mid-term survival and complications of double-crown-retained removable dental prostheses placed in the dental practice - a retrospective study.","authors":"Anna-Luisa Klotz, Stefanie Hagspiel, Christopher Büsch, Stephanie Zenthöfer, Peter Rammelsberg, Andreas Zenthöfer","doi":"10.1007/s00784-024-06090-7","DOIUrl":"https://doi.org/10.1007/s00784-024-06090-7","url":null,"abstract":"<p><strong>Objectives: </strong>Clinical data on the performance of double-crown-retained removable dental prostheses (dcRDPs), especially beyond university studies, are rare. The objective of this retrospective clinical study was to evaluate the survival and complication-freeness probabilities of dcRDPs and to identify risk factors for failure and complications in a dental practice setting.</p><p><strong>Materials and methods: </strong>Anonymized practice data of 174 patients (56.9% female) fitted with a total of 213 dcRDPs (mean of 3.3 abutment teeth per dcRDP) were evaluated up to 11 years after prothesis placement (mean observation time of 3.9 years). Probabilities of survival and complication freeness were calculated on the prosthesis- and abutment level and visualized using the Kaplan-Meier method. Factors influencing failure and complications were computed using Cox regression analyses (R Ver. 7; alpha < 0.05).</p><p><strong>Results: </strong>During our observation period, 39 (18%) of the dcRDPs failed. The mean (95% CI) overall survival was 94% (90-97%) after 2 years and 86% (80-92%) after 5 years. DcRDP survival correlated with lower patient age and more abutment teeth (P < 0.05), while other analyzed factors did not. The probability of absence of prosthesis-related complications was 92% after 2 years and 80% after 5 years. The probability of no technical complications of abutments (teeth/implants) was 85% after 2 years and 78% after 5 years, and the probability of no biological complications was 87% after 2 years and 72% after 5 years. In total, 141 dcRDPs (66.2%) faced at least one complication during the observation period.</p><p><strong>Conclusions: </strong>Double-crown-retained prostheses fitted in a dental practice had acceptable mid-term survival rates and common technical and biological complications that were frequently easily manageable. However, prosthesis performance depended on the quality and number of abutment teeth/implants. Within the limitations of this retrospective analysis, the outcomes we observed in a dental practice are comparable to, albeit slightly worse than, those found in university studies.</p><p><strong>Clinical relevance: </strong>Evaluation of the clinical performance of dcRDPs fitted in a dental practice is important to estimate durability and complication patterns in order to weigh treatment decisions.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 1","pages":"26"},"PeriodicalIF":3.1,"publicationDate":"2024-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142871615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative efficacy of In-office and walking bleach techniques in whitening of non-vital teeth.","authors":"Cristian Bersezio, Paulina Ledezma, Valentina Torres, Javiera Villagra, Daniela Aravena, Milton Kuga, Javier Martín, Eduardo Fernandez","doi":"10.1007/s00784-024-06048-9","DOIUrl":"https://doi.org/10.1007/s00784-024-06048-9","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to compare the efficacy of two non vital whitening techniques, In-office and Walking Bleach, using 35% hydrogen peroxide. The primary research question was to determine which technique achieves greater tooth color improvement.</p><p><strong>Materials and methods: </strong>Fifty non-vital anterior teeth with discoloration were randomly assigned to either the In-office (n = 25) or Walking Bleach (n = 25) groups. Tooth color was measured using a Vita EasyShade V^® spectrophotometer and visual scales (Vita Classical and Bleachguide) before treatment, after each bleaching session, and at a one-month follow-up. ΔE00, Whiteness Index (WID), and Shade Guide Unit (ΔSGU) values were calculated. Statistical analysis was performed using the Kruskal-Wallis and Mann-Whitney tests.</p><p><strong>Results: </strong>Both techniques improved tooth color, with final ΔE00 values of 10.08 for In-office and 8.12 for Walking Bleach. WID values were significantly higher in the In-office group, indicating greater whitening efficacy. Significant differences favoring the In-office method were seen after the first bleaching (p = 0.0337), and one-month follow-up (p = 0.0327).</p><p><strong>Conclusions: </strong>Both the In-office and Walking Bleach techniques effectively improve the color of non-vital teeth, with the In-office method showing slight advantages at certain times. Clinicians can choose either technique based on safety, patient needs, and clinical context to achieve optimal results.</p><p><strong>Clinical relevance: </strong>This study provides evidence that both bleaching techniques are viable options for non-vital teeth whitening. The findings help clinicians choose the most appropriate technique based on biological safety and patient needs and desired outcomes, with the In-office technique being preferable for faster results.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 1","pages":"24"},"PeriodicalIF":3.1,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical outcomes of selective removal to soft dentin versus firm dentin for deep caries lesions: a randomized controlled trial up to 5 years.","authors":"Burcu Gözetici-Çil, Tuba Çetin, Ahmad Bittar, Mutlu Özcan","doi":"10.1007/s00784-024-06109-z","DOIUrl":"https://doi.org/10.1007/s00784-024-06109-z","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to compare the success of selective removal to soft dentine (SRSD) with or without calcium silicate (CS) and selective removal to firm dentine (SRFD) in permanent dentition.</p><p><strong>Materials and methods: </strong>Between November 2018 and March 2020, 165 posterior deep caries lesions in 134 patients were included in the study and randomly assigned into test (n = 101) and control (n = 64) groups. The control group (n = 46) received the treatment of SRFD with CS, while the test group was further randomized into two groups to receive SRSD with CS (n = 45) and SRSD without CS (n = 45). An additional group (PE) consisted of teeth with exposed pulps during caries removal (n = 29). The primary outcome of the study was to assess the vitality of the teeth based on clinical and radiographic examination after five years. The secondary outcome of the study was to evaluate the influence of baseline variables and CS application on treatment outcome. The success rates of different treatment strategies were compared (Pearson chi-squared and Log-rank tests). The impact of baseline variables and treatment strategies on failure and dentin bridge formation was analyzed using binary logistic regression model.</p><p><strong>Results: </strong>The success rate for SRSD with or without CS (94.1-100%) was significantly higher compared to SRFD (75.8%) and PE (81.8%) after five years (P = 0.012). Failure was less likely for premolars. Cavity type and depth had an influence on dentin bridge formation.</p><p><strong>Conclusion: </strong>A five-year follow-up in this study demonstrated better clinical outcome for SRSD with or without CS compared to SRFD technique, irrespective of age, pre-op sensitivity, cavity type, radiographic depth and activity of the caries. Application of CS after SRSD in deeper cavities provided better healing in terms of dentin bridge formation.</p><p><strong>Clinical relevance: </strong>SRSD might be more advantageous over SRFD for the management of deep caries lesions.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 1","pages":"23"},"PeriodicalIF":3.1,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of zirconia implants in fibula and deep circumflex iliac artery flaps: a prospective 1.5-year follow-up study.","authors":"Kristian Kniha, Stephan Christian Möhlhenrich, Florian Peters, Marius Heitzer, Philipp Winnand, Anna Bock, Frank Hölzle, Ali Modabber","doi":"10.1007/s00784-024-06092-5","DOIUrl":"https://doi.org/10.1007/s00784-024-06092-5","url":null,"abstract":"<p><strong>Objectives: </strong>Follow-up results of modern zirconia implants inserted in fibula free and deep circumflex iliac artery (DCIA) flaps with fixed dentures are scarce. This study aimed to evaluate crestal bone changes and the survival rate of zirconia implants for up to 1.5 years of prospective follow-up.</p><p><strong>Materials and methods: </strong>Ten patients with six fibula and four DCIA flaps underwent reconstruction in the lower and upper jaws using vascularized composite flaps and were treated with zirconia implants. Peri-implant bone resorption was measured using radiographic images that were taken immediately after implant surgery (T1) and after three (T2), 12 (T3), and 18 months (T4).</p><p><strong>Results: </strong>Between the day of operation and T3, a significant increase in distance was recorded for the fibula flaps. After occlusal loading (T2) of 41 zirconia implants for up to 1.5 years, no significant bone loss in each flap was observed overall. An overall survival rate of 96.56% was reported.</p><p><strong>Conclusions: </strong>When comparing both composite flaps, no significant difference in periimplant bone levels was measured between the same timepoints.</p><p><strong>Clinical relevance: </strong>For fixed dentures, modern zirconia implants can be used in the DCIA and fibula flaps, however further long-term data is necessary.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 1","pages":"21"},"PeriodicalIF":3.1,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142853290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Disease burden and health inequality of older adults with edentulism and the projected trend until 2040: based on the global burden of disease study 2021.","authors":"Weizhen Guan, Jing Li, Qian Liang, Yushan Huang, Shunhang Li, Xiaoshuang Xu, Yilin Zhang, Fei Wang, Xin Xu","doi":"10.1007/s00784-024-06111-5","DOIUrl":"https://doi.org/10.1007/s00784-024-06111-5","url":null,"abstract":"<p><strong>Objectives: </strong>To comprehensively analyze the current situation and the trends over the next 21 years, focusing on health inequalities related to edentulism among the elderly across global regions.</p><p><strong>Materials and methods: </strong>Data on edentulism in older adults were collected from the 2021 global burden of disease (GBD) study. Disease burden trends were analyzed using a joinpoint model. We used the Slope Index of Inequality (SII) and the Concentration Index (CI) to assess health inequalities. A Bayesian age-period-cohort (BAPC) model was used to analyze the projected trend of prevalence up to 2040.</p><p><strong>Results: </strong>The number of incident, prevalent, and years lived with disability (YLD) cases of edentulism in older adults is increasing globally, while the rate is declining. According to the analysis of health inequality, the burden of edentulism among older adults was gradually concentrated in countries with lower Sociodemographic Index (SDI). Significant downward trends were expected in the global age-standardized prevalence rate (ASPR) of edentulism for both genders from 2020 to 2040; however, the number is increasing.</p><p><strong>Conclusions: </strong>Taken together, the burden of edentulism in older people remains high and generally shifts from higher-SDI countries to lower-SDI countries. There are great differences between countries, and effective measures should be taken in countries with poorer economies.</p><p><strong>Clinical relevance: </strong>The disease burden of edentulism in older adults is gradually shifting towards lower SDI countries. It is crucial to optimize the utilization and allocation of healthcare resources to reduce health inequities in edentulism in older adults.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 1","pages":"22"},"PeriodicalIF":3.1,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142853289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of customized bioactive glass in experimental composites on dentin bond strength after 12 months of aging.","authors":"Matej Par, Ksenija Dukaric, Danijela Marovic, Tobias T Tauböck, Thomas Attin, Zrinka Tarle","doi":"10.1007/s00784-024-06108-0","DOIUrl":"https://doi.org/10.1007/s00784-024-06108-0","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to investigate the effect of a customized low-sodium bioactive glass (BG) fillers in experimental resin composites on their bond strength to dentin after 12 months of artificial aging. Specifically, it evaluated whether the bond strength was affected by different BG concentrations (0, 10, 20, 40 wt%) and artificial aging durations (1, 6, and 12 months).</p><p><strong>Materials and methods: </strong>Experimental composites were prepared with 10, 20, and 40 wt% of a customized low-sodium fluoride-containing BG. The experimental composite with 0 wt% BG was used as a control, while Beautifil II (Shofu) was used as an external reference material. A universal adhesive system was applied to dentin substrates and composite build-ups were made. Bond strength was measured using a macro-shear bond strength test, and Weibull statistics were used to assess the reliability of the materials. Failure modes were analyzed to evaluate the type of the fracture.</p><p><strong>Results: </strong>After 12 months, the bond strength of all experimental composites remained stable and comparable to the control material, with statistically significant improvements between 6 and 12 months for all experimental materials. The bond strength was statistically similar across materials, except at the 12-month point, where the 20 wt% BG-composite showed significantly higher bond strength than the 40 wt% BG-composite. The frequency of mixed failures in composite increased after 12 months, particularly in experimental composites containing higher BG content.</p><p><strong>Conclusions: </strong>The incorporation of a customized low- sodium BG into resin composites did not negatively impact their bond strength to dentin over 12 months. Instead, bond strength improved over time, and the composites remained mechanically stable, although a higher incidence of mixed failures was observed with increased BG content.</p><p><strong>Clinical relevance: </strong>The customized low-sodium BG demonstrated stable bond strength over the 12-month period, offering a promising option for functional fillers in restorative composites without compromising the longevity of the adhesive-dentin interface.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 1","pages":"19"},"PeriodicalIF":3.1,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142846058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of fissure sealants in 8- to 10-year-olds with and without molar-incisor hypomineralization (MIH) - results from a cross-sectional epidemiological study.","authors":"Felicitas Zöllner, Karl-Ferdinand Fresen, Ramy Gaballah, Helen Schill, Vinay Pitchika, Stefanie Amend, Norbert Krämer, Jan Kühnisch","doi":"10.1007/s00784-024-06083-6","DOIUrl":"https://doi.org/10.1007/s00784-024-06083-6","url":null,"abstract":"<p><strong>Objective: </strong>This cross-sectional study aimed to investigate the use, quality, and caries-preventive effects of fissure sealants (FSs) in 8- to 10-year-olds with and without molar-incisor hypomineralization (MIH).</p><p><strong>Materials and methods: </strong>A total of 5,418 children (2,692 males, 2,726 females) were examined via standard instruments (dental mirrors, CPI probes, adequate lighting, mobile examination tables, and air syringes) and methods for the recording of caries (DMFT index, WHO method) and FSs. The classification of MIH followed the recommendations of the European Academy of Pediatric Dentistry (EAPD). Statistical analysis included descriptive analysis and mixed-effects logistic regression models.</p><p><strong>Results: </strong>59.0% of all children had at least one FS; this percentage was 57.8% in the MIH group. The proportions of fully intact sealants and minimal, moderate, or nearly complete loss of retention were 31.7%, 48.3%, 16.8%, and 3.2%, respectively. The mean caries experience was low, at 0.2 DMFT in the whole population. Lower DMFT means were registered in individuals with FSs without MIH (0.1) and with MIH (0.1). The regression analysis revealed a significant caries-protective effect of FSs and MIH in relation to the overall caries burden. In addition, the caries-protective effect was greater in individuals with fully retained sealants (aOR 0.269) than in those with minimal (aOR 0.346), moderate (aOR 0.567) or nearly complete loss of retention (aOR 0.721).</p><p><strong>Conclusion: </strong>This study documented the comparable use, quality, and caries-preventive effects of FSs in individuals and permanent molar with and without MIH.</p><p><strong>Clinical relevance: </strong>FSs are caries protective in children with and without MIH.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 1","pages":"20"},"PeriodicalIF":3.1,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142846059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of intra-oral botulinum toxin injection in comparison to the extra-oral approach on pain and quality of life in patients with myofascial pain: a randomized clinical trial.","authors":"Alshaimaa Ahmed Shabaan, Islam Kassem, Inass Aboulmagd, Islam A Amer, Ahmed Shaaban, Mohamed Abd-El-Ghafour, Shaimaa Mohsen Refahee","doi":"10.1007/s00784-024-06051-0","DOIUrl":"https://doi.org/10.1007/s00784-024-06051-0","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate and compare the effectiveness of the ultrasound-guided intra-oral and extra-oral transcutaneous injection techniques on the clinical outcome variables in patients with myofascial trigger points within the masseter muscle.</p><p><strong>Materials and methods: </strong>This prospective randomized trial included 42 patients diagnosed with myofascial pain. Patients were randomly allocated into one of two groups based on the technique of trigger point injection: intraoral and extraoral injection technique groups. Each trigger point was injected with 0.1 ml of botulinum-A toxin guided by ultrasound. Pain intensity, mouth opening, and patient quality of life were monitored six months post-injection.</p><p><strong>Results: </strong>The pain scores were significantly higher in the extraoral group during all follow-up assessments, whereas the MMO was considerably greater in the intraoral group up to three months of follow-up (p < 0.008). However, the difference in MMO ceased to be statistically non-significant after six months of follow-up (p = 0.927). Additionally, the patient's quality of life score was significantly higher in the intraoral group compared to the extraoral group (p < 0.001) at both the three- and six-month follow-ups.</p><p><strong>Conclusion: </strong>The intraoral injection technique might be an effective treatment modality for myofascial trigger points in the masseter muscle. It produces pain relief, increases mouth opening, and enhances the overall quality of life compared to the extraoral injection technique.</p><p><strong>Clinical significance: </strong>The intraoral injection technique for myofascial trigger points is more effective than the extraoral technique; it reduces the need for additional injections, saves money, and enhances patients' quality of life.</p><p><strong>Trial registration: </strong>Clinicaltrials.gov (NCT05673655).</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 1","pages":"18"},"PeriodicalIF":3.1,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142834085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}