Clinical Oral Investigations最新文献

{"title":"Impact of laser and sonic activated irrigation on obturation quality in conservatively prepared mandibular molars: a micro-CT analysis.","authors":"Megan Yamaguchi, Ane Poly, Alexander Huynh, Poorya Jalali","doi":"10.1007/s00784-025-06373-7","DOIUrl":"https://doi.org/10.1007/s00784-025-06373-7","url":null,"abstract":"<p><strong>Introduction: </strong>The objective of this study was to compare the quality of obturation in the mesial roots of mandibular molars with isthmuses, using Er, Cr: YSGG laser and sonic-activated irrigation, assessed by micro-CT scanning.</p><p><strong>Methods: </strong>Mesial canals of extracted mandibular molars were instrumented to a master apical file size of 20/V06. The final irrigation protocol included 2.5% NaOCl, 17% EDTA, and a final rinse with 2.5% NaOCl, applied with either sonic-activated or laser-activated irrigation using the WaterLase iPlus (BIOLASE, Inc, Foothill Ranch, CA). Canals were obturated with Bioceramic Sealer HiFlow (Brasseler, Savannah, GA) and gutta-percha cones. Micro-computed tomography scans were obtained before and after obturation to evaluate the quality of obturation, determined by the percentage of unfilled spaces in each irrigation group.</p><p><strong>Results: </strong>There was no statistically significant difference in baseline canal characteristics, including isthmus width, canal volume, root curvature, and Weine classification between the groups (p > 0.05). In the post-obturation evaluation with micro-CT, the mean percentage of unfilled spaces was higher in the sonic group (17.24%) than in the laser group (10.73%), showing a statistically significant difference (p < 0.05).</p><p><strong>Conclusions: </strong>This study suggests that laser-activated irrigation may improve the quality of obturation in mandibular molars with isthmuses compared to sonic-activated irrigation.</p><p><strong>Clinical significance: </strong>This study demonstrates that laser-activated irrigation can lead to a higher quality of obturation in conservatively instrumented canals by reducing the percentage of unfilled spaces. However, these findings should be cautiously interpreted, as the improved obturation quality observed may not directly translate to clinical outcomes. Further research is needed to determine if this advanteg influence long-term treatment success.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 7","pages":"344"},"PeriodicalIF":3.1,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144324667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of CAD/CAM titanium fixed lingual retainer versus conventional stainless steel fixed retainer (randomized controlled clinical trial).","authors":"Nada E A Elhosseiny, Wessam M Marzouk, Mostafa A Tageldin","doi":"10.1007/s00784-025-06418-x","DOIUrl":"10.1007/s00784-025-06418-x","url":null,"abstract":"","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 7","pages":"343"},"PeriodicalIF":3.1,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12174219/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144315985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accuracy of intraoral scans of the edentulous maxilla - an in vitro study.","authors":"Panagiotis Kontis, Jan-Frederik Güth, Christine Keul","doi":"10.1007/s00784-025-06419-w","DOIUrl":"10.1007/s00784-025-06419-w","url":null,"abstract":"<p><strong>Objective: </strong>Investigation of the accuracy of various digitalization methods and the accuracy of digitalization of different regions of the edentulous maxilla.</p><p><strong>Material and method: </strong>A PEEK edentulous maxilla with four spherical reference geometries served as the testing model. A reference dataset (REF) was generated using a highly accurate 3D measuring instrument. The testing model was digitized as follows (n = 25/group). Direct digitalization (DD) with intraoral scanners (IOS): 1) Cerec AC Primescan (PRI), 2) Trios 4 Move (TR4), 3) Trios 3 Wireless (TR3), 4) Indirect digitalization of PVS impression with laboratory scanner 3Shape D810 (D8I). Three-dimensional deviations between REF and TEST were evaluated (GOM Inspect) in different areas of the model: 1) Complete Surface, 2) Alveolar Ridge, 3) Vestibular Ridge, 4) Palate, 5) Posterior Seal, 6) Border. Significant differences were analyzed with the Games-Howell test for trueness (p < 0.05) and multiple comparisons Levene's test for precision (for IOS: p < 0.008, for area: p < 0.003).</p><p><strong>Results: </strong>Group D8I revealed the best trueness for Complete Surface (7.95 µm), Palate (9.11 µm), and Border (20.22 µm). Alveolar Ridge showed for PRI (16.45 µm) and TR4 (8.96 µm) the highest trueness. Groups TR4 and PRI resulted in significantly higher precision for Alveolar Ridge. Groups TR4 and D8I demonstrated the highest precision for Palate. Complete Surface and Alveolar Ridge showed for all digitalization methods significantly higher precision.</p><p><strong>Conclusions: </strong>Indirect digitalization of impressions remains the most accurate approach for capturing edentulous jaws, whereas IOS deliver datasets with clinically acceptable accuracy. Peripheral regions characterized by limited accessibility and smooth surface morphology tend to demonstrate increased deviations in the resulting digital datasets.</p><p><strong>Clinical relevance: </strong>Indirect digitalization of the impression still appears to be the most appropriate technique to access the clinical workflow for full dentures due to the superior digitalization trueness and inclusion of functional movements. Direct and indirect digitalization show nearly equal values for precision.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 7","pages":"342"},"PeriodicalIF":3.1,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12170734/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144309658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Root canal irrigants and their role in the adhesion of pre-endodontic restorations.","authors":"J Francinelli, C Mazzitelli, U Josic, D D'Urso, E Mancuso, G M Moretto, A Mazzoni, S A Salgarello, Lorenzo Breschi, T Maravic","doi":"10.1007/s00784-025-06421-2","DOIUrl":"https://doi.org/10.1007/s00784-025-06421-2","url":null,"abstract":"","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 7","pages":"340"},"PeriodicalIF":3.1,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144301255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adjuvant effects of injectable platelet-rich fibrin (i-PRF) in the non-surgical periodontal therapy: a split-mouth randomized controlled clinical trial.","authors":"Roberta de Oliveira Alves, Caroline Garcia Orsi, Jovânia Alves Oliveira, Gabriella Lopes de Rezende Barbosa, Guilherme José Pimentel Lopes de Oliveira, Priscilla Barbosa Ferreira Soares","doi":"10.1007/s00784-025-06423-0","DOIUrl":"10.1007/s00784-025-06423-0","url":null,"abstract":"<p><strong>Objective: </strong>To assess the impact of injectable platelet-rich fibrin (i-PRF) as an adjunct to scaling and root planing (SRP) in patients with periodontitis.</p><p><strong>Materials and methods: </strong>Twenty-four patients, with two pairs of contralateral teeth (probing depth [PD] ≥ 5 mm), were enrolled. The tooth pairs were randomly assigned to either the control group (SRP, n = 149 sites) or the experimental group (SRP + i-PRF, n = 135 sites). The clinical parameters PD, gingival recession (GR), clinical attachment level (CAL), plaque index (PI), and full mouth bleeding on probing (fBOP) were evaluated at baseline and 45 and 90 days. Radiographic analysis measured the distance from the cementoenamel junction to the alveolar bone crest (CEJ-BC) at baseline and 90 days.</p><p><strong>Results: </strong>Both groups showed significant reductions in PD, CAL, fBOP, and PI from baseline to 45 days (p < 0.001), without significant differences between the groups (p > 0.05). The test group exhibited increased GR at 45 days (p < 0.05). CEJ-BC decreased in both groups at 90 days with no significant intergroup difference (p > 0.05). At 90 days, no significant intra- or intergroup differences were observed in any of the clinical parameters (p > 0.05).</p><p><strong>Conclusion: </strong>SRP alone or combined with i-PRF resulted in comparable clinical and radiographic improvements in patients with periodontitis. Adjunctive i-PRF did not offer significant additional benefits.</p><p><strong>Clinical relevance: </strong>This study shows SRP alone and SRP + i-PRF yield satisfactory periodontal outcomes. Moreover, this study introduces the injection of i-PRF around the periodontal pocket, which, to the best of our knowledge, has not been extensively explored in the existing literature.</p><p><strong>Trial registration: </strong>https://ensaiosclinicos.gov.br/ : RBR-52h647m.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 7","pages":"341"},"PeriodicalIF":3.1,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144301254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Peridontopathogenic key species in correlation to the current classification system.","authors":"Bernd Sigusch, Stefan Kranz, Markus Heyder, Anna Weber, André Güllmar, Nargis Mahmudova, Markus Reise","doi":"10.1007/s00784-025-06413-2","DOIUrl":"10.1007/s00784-025-06413-2","url":null,"abstract":"<p><strong>Objective: </strong>The present in-vivo-study aimed on identifying periodontopathogenic key species in correlation to the current classification system. It was evaluated if there is an association in frequency to single periodontitis stages and grades.</p><p><strong>Materials and methods: </strong>The study included 100 patients that were assigned to 4 test groups (periodontitis stages I-IV) and one healthy control group, each n = 20. Samples were collected from the deepest pockets of each sextant and analyzed for: Fusobacterium nucleatum (F.n.), Aggregatibacter actinomycetemcomitans (A.a.), Porphyromonas gingivalis (P.g.), Tannerella forsythia (T.f.), Treponema denticola (T.d.) and Enterococcus faecalis (E.f.).</p><p><strong>Results: </strong>Among all samples, F.n. was most common (98%), followed by T.f. (73%), T.d. (66%), P.g. (45%), A.a. (12%) and E.f. (3%). Controls showed no P.g., A.a. and E.f.. In stage I T.f. (p < 0.001) and T.d. (p = 0.022) were significantly more frequent. In stages II and III, P.g., T.f. and T.d. were significant (p < 0,001). In stage IV, A.a. (p = 0.003), P.g., T.f. and T.d. (p < 0.001) occurred with significant higher frequency. Grade C was more common among stage III and IV (20%) as compared to stage I and II (2.5%). Patients diagnosed with stage IV and grade C, showed significant association to A.a. (p = 0.001) and P.g. (p = 0.021).</p><p><strong>Conclusions: </strong>The present investigation proved significant correlation between periodontopathogenic key species, disease severity and progression risk. A.a. and P.g were most frequently in stage IV and grade C.</p><p><strong>Clinical relevance: </strong>Microbial analysis provide additional information in regard to the classification of periodontitis.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 7","pages":"339"},"PeriodicalIF":3.1,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12159085/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144274323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of conditioning regimen intensity on periodontal health in haematopoietic cell transplantation recipients: a 5-year multicentre prospective cohort study.","authors":"Lucky L A van Gennip, Marjolein S Bulthuis, Renske Z Thomas, Ewald M Bronkhorst, Gerjon Hannink, Alexa M G A Laheij, Judith E Raber-Durlacher, Frederik R Rozema, Michael T Brennan, Inger von Bültzingslöwen, Nicole M A Blijlevens, Stephanie J M van Leeuwen, Marie-Charlotte D N J M Huysmans","doi":"10.1007/s00784-025-06393-3","DOIUrl":"10.1007/s00784-025-06393-3","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate periodontal health and its association with conditioning intensity over five years post-HCT.</p><p><strong>Materials and methods: </strong>This multicentre prospective study included 104 patients from two Dutch centres. Probing pocket depth (PPD), bleeding on probing (BOP), and buccal gingival recession (GR) were assessed pre-HCT and at three (n = 34), six (n = 45), twelve (n = 46), eighteen months (n = 30), and five years (n = 36) post-HCT. Regression models evaluated associations with conditioning intensity and time since HCT.</p><p><strong>Results: </strong>HCT recipients had a median age of 58 years; 56% were male, and 59% received an allogeneic transplant. At baseline, mean PPD was 2.3 mm (31% had PPD ≥ 6 mm), mean BOP was 23%, and the median number of teeth with GR ≥ 1 mm was nine. Conditioning intensity was not significantly associated with PPD, GR, or BOP over time. Mean PPD decreased slightly at twelve months post-HCT (-0.21 mm (95%CI -0.28, -0.14)) but increased marginally at five years (0.12 mm (95%CI 0.08, 0.16)) compared to baseline. GR increased gradually with 0.13 mm (95%CI 0.07, 0.19) at twelve months, and 0.16 mm (95%CI 0.10, 0.23) at five years. BOP declined at twelve months (-11% (95%CI -15, -8)) but returned to baseline at five years (-1% (95%CI -5, 4)).</p><p><strong>Conclusions: </strong>Our results suggest that conditioning intensity does not affect long-term periodontal health. Periodontal changes up to five years post-HCT were small.</p><p><strong>Clinical relevance: </strong>Conditioning intensity may not be a key determinant of post-HCT periodontal health. Post-HCT periodontal deterioration was not found in our study.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 7","pages":"338"},"PeriodicalIF":3.1,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12159097/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144274324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of matrix system on the quality of proximal contact in posterior bulk-fill resin composite restorations- an in vitro study.","authors":"Laryssa Silva da Cunha, Karoline Guará Brusaca Almeida Cavalcanti, Thiago Silva Peres, Andres Felipe Millan Cardenas, Gisele Rodrigues da Silva, Carlos José Soares","doi":"10.1007/s00784-025-06402-5","DOIUrl":"https://doi.org/10.1007/s00784-025-06402-5","url":null,"abstract":"<p><strong>Objective: </strong>Evaluate the effect of matrix systems on the proximal contact force (N) between molars and premolars in two class-II bulk-fill resin composite restorations.</p><p><strong>Methods: </strong>The Typodont model of the first molar, with adjacent molar and premolar simulating the periodontal ligament was used to analyze proximal contact in two class-II restorations (n = 10) made with OPUS Bulk Fill resin composite. Four types of matrices were tested: two sectional (Palodent V3 and Unimatrix R) and two circumferential (SuperMat and universal metal matrix. Intact tooth was used as the control group). The specimens were radiographed and proximal contact force (N) were measured in a microtensile testing machine (Odeme). Data were analyzed using two-way ANOVA followed by the Tukey and Dunnet tests (α = 0.05).</p><p><strong>Results: </strong>The contact force on the premolar was lower than that on the molar (P < 0.001) irrespective of the matrix system. The sectional matrices produced similar proximal contact forces as the intact tooth (P = 0.109) and higher than the circumferential matrices (P < 0.001), irrespective of the tooth-type contact. The radiographic analysis showed predominantly perfect proximal contact in the sectional matrix specimens.</p><p><strong>Conclusions: </strong>The contour and proximal contact forces were influenced by the matrix systems and tooth contact location. The sectional matrices had better proximal contact force than the circumferential matrices.</p><p><strong>Clinical relevance: </strong>Compared with circumferential matrices, sectional matrices are more flexible and can be moved easily to the direction of the adjacent tooth to produce better proximal contact in class-II bulk-fill resin composite restorations.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 7","pages":"337"},"PeriodicalIF":3.1,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144257473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictability of curve of Spee levelling and vertical tooth movements in the lower arch with clear aligners based on cone-beam computed tomography.","authors":"Shangyou Wen, Xiaoyue Han, Xian He, Qi Fan, Xuechun Yuan, Wenli Lai, Hu Long","doi":"10.1007/s00784-025-06388-0","DOIUrl":"https://doi.org/10.1007/s00784-025-06388-0","url":null,"abstract":"","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 7","pages":"336"},"PeriodicalIF":3.1,"publicationDate":"2025-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144246697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical outcome and technical complications of bimaxillary full-arch implant-supported metal-resin fixed dental prostheses with or without ceramic molars: 5-year results.","authors":"Gerald Krennmair, Michael Weinländer, Lukas Postl, Michael Malek, Thomas Forstner, Helfried Hulla, Gerald Krennmair","doi":"10.1007/s00784-025-06409-y","DOIUrl":"10.1007/s00784-025-06409-y","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the prevalence of prosthetic-related technical complications (PRTC) for bimaxillary implant-supported fixed complete metal-resin prostheses (ISFP) with (Zrm-ISFP) or without (r-ISFP) occlusal support by incorporation of zirconium molars.</p><p><strong>Materials and methods: </strong>Two cohorts of patients with bimaxillary ISFP subdivided into test group (TG; Zrm-ISFP) and control group (CG, r-ISFP) providing a 5-year follow-op program were retrospectively analyzed. For both groups the prevalence of PRTC was assessed and compared including evaluation of their occurrence in different time periods (-1 year, > 1-3-years; > 3-5-years post-loading). Additionally, implant/prosthesis survival-rates, peri-implant-marginal bone loss (MBL) and implant-related-technical complications were evaluated and compared.</p><p><strong>Results: </strong>For the 29 patients with bimaxillary ISFP subdivided into 14 TG [Zrm-ISFP] and 15 CG [r-ISFP]) and followed-up for 5 years no implant and denture loss was seen (survival 100%). However, the prevalence of PRTC such as acrylic-tooth fracture (p < 0.001) and acrylic-tooth repair (p = 0.015) differed significantly between TG (Zrm-ISFP) and CG (r-ISFP). For the CG, an evidently higher time-related ongoing increase (-1 yr: n = 9; > 1-3yrs: n = 23; > 3-5yrs: n = 34) of the prevalence of PRTC was noted compared to TG ( -1 yr: n = 2; > 1-3yrs: n = 3; > 3-5yrs: n = 7). In contrast, PRTC such as denture rebasing/reduction, denture cleaning, screw hole repair and implant-related technical complications and peri-implant MBL did not differ between TG and CG.</p><p><strong>Conclusion/clinical relevance: </strong>The modified metal-resin ISFPs incorporating zirconium molars/quadrants used for bimaxillary ISFP reduce the prevalence of PRTC and combine beneficial effects such as cost effectiveness and reparability of metal-resin and occlusal stability and reduced wear of complete zirconium prostheses.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 6","pages":"335"},"PeriodicalIF":3.1,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12141106/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144224575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}