Clinical Oral Investigations最新文献

{"title":"Which volatile components in breath associated with lung cancer could contribute to halitosis?","authors":"Peng Gong, Xiao Xian Qian","doi":"10.1007/s00784-025-06460-9","DOIUrl":"https://doi.org/10.1007/s00784-025-06460-9","url":null,"abstract":"","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 8","pages":"386"},"PeriodicalIF":3.1,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: Is pre-operative full mouth plaque score related to inflammatory complications in lower third molar surgery? Cohort study.","authors":"Roberto Pippi, Maria Luisa Lauteri, Stefano Petti","doi":"10.1007/s00784-025-06461-8","DOIUrl":"https://doi.org/10.1007/s00784-025-06461-8","url":null,"abstract":"","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 8","pages":"385"},"PeriodicalIF":3.1,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficiency and limitations of polywave light-curing units in restorative dentistry: a systematic review.","authors":"Eduardo Fernández Godoy, Alain Chaple Gil, Rodrigo Caviedes Thomas, Cristian Bersezio Miranda, Javier Martín Casielles, Gonzalo Rodríguez Martínez, Pablo Angel Aguirre","doi":"10.1007/s00784-025-06457-4","DOIUrl":"https://doi.org/10.1007/s00784-025-06457-4","url":null,"abstract":"<p><strong>Objectives: </strong>This systematic review aimed to evaluate the efficiency and limitations of polywave light-curing units (LCUs) compared to monowave LCUs for the polymerization of resin-based composites in restorative dentistry. The primary outcomes assessed included the degree of conversion (DC), microhardness, and depth of cure (DoC).</p><p><strong>Materials and methods: </strong>A systematic literature search was conducted following PRISMA 2020 guidelines across five electronic databases: PubMed, Scopus, Web of Science, Cochrane Library, and EMBASE. In vitro studies comparing polywave and monowave LCUs in terms of polymerization outcomes were included. Two reviewers independently performed study selection, data extraction, and risk of bias assessment using the RoBDEMAT tool. Due to substantial methodological heterogeneity (I² >75%), a narrative synthesis was conducted in place of a meta-analysis.</p><p><strong>Results: </strong>Twenty-six in vitro studies were included. Polywave LCUs achieved significantly higher degree of conversion (83.7-92%) than monowave LCUs (70-81%), particularly with TPO-containing composites (p < 0.05). Microhardness was greater in 15 studies, with bottom/top ratios often exceeding 0.85. Depth of cure reached 4.3 mm with polywave LCUs versus 3.6 mm with monowave devices (p < 0.001). Temperature rise was higher with polywave units (up to 12 °C), and color stability outcomes (ΔEab = 2.1-4.97) varied widely across materials, with no consistent advantage for polywave LCUs; differences were mainly attributed to composite formulation.</p><p><strong>Conclusions: </strong>Polywave LCUs enhance polymerization efficiency compared to monowave LCUs, especially for bulk-fill and photoinitiator-diverse composites. Nevertheless, their clinical use requires protocol optimization to manage irradiance variability and mitigate thermal risks.</p><p><strong>Clinical relevance: </strong>This review highlights the importance of matching the spectral output of light-curing units (LCUs) with the photoinitiators used in composite resins. Polywave LCUs showed superior outcomes in degree of conversion, microhardness, and depth of cure especially in composites containing TPO or Ivocerin. However, their higher thermal emission and beam non-uniformity may pose clinical challenges. Selecting an appropriate LCU should consider the composite's photoinitiator system and cavity depth to avoid under-curing and ensure restoration longevity. These findings support a more tailored, evidence-based approach to light-curing in contemporary restorative dentistry.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 8","pages":"384"},"PeriodicalIF":3.1,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Facial artery-based flap for oral and maxillofacial defects: a narrative review.","authors":"Qingyan Qin, Tianshu Chu, Yitong Zhao, Yongzhen Fu, Huihui Yang, Qilin Liu","doi":"10.1007/s00784-025-06219-2","DOIUrl":"https://doi.org/10.1007/s00784-025-06219-2","url":null,"abstract":"<p><strong>Objectives: </strong>The reconstruction of oral and maxillofacial defects poses considerable challenges due to their complex nature. Surgeons often face difficulties in selecting the most appropriate flap for such repairs. The procedure involving vascularized free flaps typically requires prolonged procedural times and places significant demands on surgical teams. In specific cases, facial artery-based flaps serve as an effective alternative. This article discusses the current utilization and future prospects of facial artery-based flaps in the reconstruction of oral and maxillofacial defects.</p><p><strong>Materials and methods: </strong>A comprehensive review of the literature was undertaken to explore the anatomy of the facial artery and its associated structures, including muscles, glands, and nerves. The review encompasses various facial artery-derived flaps such as the submental island flap (SIF), facial artery flap (FAIF), nasolabial island flap (NAIF), facial artery myomucosal island flap (FAMMIF), and submandibular gland flap (SMGF).</p><p><strong>Result: </strong>The identified flaps were classified based on the branches of the facial artery, with a concise overview of their preparation methods. This article provides an in-depth discussion of the indications, contraindications, and recent advancements related to facial artery-based flaps.</p><p><strong>Conclusion: </strong>Facial artery-based flaps are noted for their ease of elevation and versatility, making them valuable tools for addressing complex maxillofacial defects. Additionally, these flaps can be utilized in combination to form chimeric flaps, thereby expanding their application.</p><p><strong>Clinical relevance: </strong>This article presents a diverse range of facial artery-based flaps, offering clinicians an enhanced selection of options for the effective repair of maxillofacial defects.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 8","pages":"382"},"PeriodicalIF":3.1,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144625498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dental recommendation and prescribing patterns for systemic analgesics - a cross-sectional study.","authors":"Diana Heimes, Nina Viktoria Holz, Andreas Pabst, Philipp Becker, Anke Hollinderbäumer, Anita Kloss-Brandstätter, Daniel Müller-Winter, Daniel Stephan, Peer W Kämmerer","doi":"10.1007/s00784-025-06403-4","DOIUrl":"10.1007/s00784-025-06403-4","url":null,"abstract":"<p><strong>Objective: </strong>Pain management is a significant challenge in dental care, making analgesics the most commonly prescribed drugs by dentists. Since many analgesics are available over the counter, data on their use in dental practice is imprecise. This study aimed to gather information on the prescription and recommendation patterns for systemic analgesics among dental practitioners.</p><p><strong>Materials and methods: </strong>A total of 1,746 dentists were contacted via email and letter and invited to participate in an online survey. The survey covered four sections: personal data, acute and chronic pain management, preemptive analgesia, and managing at-risk patients.</p><p><strong>Results: </strong>232 dentists participated in the survey. Ibuprofen, typically at 600 mg, was the most commonly recommended analgesic for both acute and chronic pain. For acute pain, analgesics were prescribed for 1-3 days on average. Two-thirds of respondents did not use preemptive analgesia, and of those who did, 96.56% recommended ibuprofen. Notably, in 22.16% of cases, contraindicated analgesics were recommended for patients with renal, liver, or cardiovascular conditions.</p><p><strong>Conclusions: </strong>The analgesics recommended by dentists are limited in variety and often do not align with specific clinical indications. Nonsteroidal anti-inflammatory drugs, especially ibuprofen, are commonly used long-term, despite conflicting recommendations. A significant number of dentists prescribed contraindicated medications to at-risk patients. Only one-third utilized preemptive analgesia, underscoring the need for improved education and greater use of this approach in dental practice.</p><p><strong>Clinical relevance: </strong>There is a clear need for enhanced training on analgesic use and preemptive analgesia to improve patient safety, particularly for those with risk factors.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 8","pages":"383"},"PeriodicalIF":3.1,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12259747/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144625423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of 0.8% Hyaluronic Acid-Based Gel on Clinical and Biomolecular parameters in the surgical periodontal treatment of Stage III periodontitis patients: a randomized, split-mouth clinical trial.","authors":"Aslı Şener, Figen Öngöz Dede, Bahattin Avci, Umut Balli","doi":"10.1007/s00784-025-06449-4","DOIUrl":"10.1007/s00784-025-06449-4","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to assess the effect of the application of 0.8% hyaluronic acid (HA) gel together with open flap debridement (OFD) on clinical parameters and inflammatory and oxidative biomarkers in gingival crevicular fluid (GCF) of the patients with stage III periodontitis.</p><p><strong>Materials and methods: </strong>This split-mouth study included 18 patients diagnosed with Stage III Grade B or C periodontitis. Quadrants were randomly assigned to test (OFD + 0.8% HA gel) and control groups (OFD alone). Clinical parameters and GCF samples were obtained at the treated sites at baseline (T0), at pre-surgery (T1), 1 month (T2) and 6 months (T3) post-surgery. Interleukin (IL)-6, IL-8, IL-10, IL-17 A, total antioxidant status (TAS), and total oxidant status (TOS) levels in GCF were analyzed using enzyme-linked immunosorbent assay.</p><p><strong>Results: </strong>The lower GCF IL-6, IL-8, IL-17 A and TOS levels and higher GCF IL-10 and TAS levels were found after treatment (T1,T2,T3) compared to the T0 period in intragroup comparisons (P < 0.05). There were statistically significantly higher GCF IL-10 levels in the T2 and T3 periods and significantly lower GCF IL-17 A levels in the T3 period in the test group compared to the control group (P < 0.05), no significant difference was determined between the groups in GCF IL-6, IL-8, TAS and TOS levels during the time periods.</p><p><strong>Conclusion: </strong>The local application of 0.8% HA gel with OFD provides to beneficial effect GCF IL-10 and IL-17 A levels in severe periodontitis patients.</p><p><strong>Clinical relevance: </strong>The application of 0.8% HA gel addictive with OFD provides positive results in GCF IL-10 and IL-17 A levels in patients with Stage III periodontitis compared to OFD alone.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 8","pages":"381"},"PeriodicalIF":3.1,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144607716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and microbiological effects of a propolis toothpaste in patients with periodontitis under supportive periodontal therapy: a randomized double-blind clinical trial.","authors":"Kazu Takeuchi-Hatanaka, Masahiro Ito, Yoshihiro Hayashi, Hiroe Maruyama, Hiroyuki Kono, Yuki Shinoda-Ito, Kazuhiro Omori, Shogo Takashiba","doi":"10.1007/s00784-025-06456-5","DOIUrl":"10.1007/s00784-025-06456-5","url":null,"abstract":"","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 8","pages":"379"},"PeriodicalIF":3.1,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12241118/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144590614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Applicability of intraoral scans for presurgical orthopedic treatment of cleft lip and palate in infants: a prospective non-randomized comparative study.","authors":"Christiane Keil, Michaela Buckova, Sheila Keil, Louis Hartmann, Wilhelm Schlupp, Thomas Zerjatke, Theodosia Bartzela, Günter Lauer","doi":"10.1007/s00784-025-06444-9","DOIUrl":"10.1007/s00784-025-06444-9","url":null,"abstract":"<p><strong>Objectives: </strong>This in vivo study evaluated the reliability of digital impressions from intraoral scans compared to digital scans of plaster casts of the edentulous maxilla of infants with cleft lip and palate (CLP).</p><p><strong>Materials and methods: </strong>To compare and evaluate the dimensional accuracy of digital and conventional impressions, 52 infants with CLP were selected. Conventional plaster and digital impressions were taken from each patient before surgical closure of the lips and/or palate. Plaster casts were digitized using the intraoral scanner. Eight linear distances were measured and 3D superimpositions were performed. Pearson's correlation, mean difference and root mean square were calculated to compare the two impression methods.</p><p><strong>Results: </strong>Regardless of the form of CLP, the IOS and the plaster casts correlated very well. The measured linear dimensions of the IOS were greater than those of the digitized plaster casts. Although the linear measurements showed differences of up to 0.89 mm, superimpositions showed that the two impression methods did not differ in a clinically relevant way.</p><p><strong>Conclusions: </strong>No clinically relevant difference in accuracy was found between IOS and the plaster casts. When investigating the accuracy, 3D analysis should always be preferred to 2D analysis.</p><p><strong>Clinical relevance: </strong>This study confirms that IOS is a reliable and clinical valuable alternative for infants with CLP. IOS eliminates risks associated with traditional methods, providing a safer and more efficient workflow for PSIO. Despite minor differences in dimensional accuracy, these variations are clinically negligible and do not impact treatment planning or appliance fabrication.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 8","pages":"378"},"PeriodicalIF":3.1,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12241132/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144590613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of cuspal deflection and fracture resistance of endodontically treated teeth restored with different restorative material combinations.","authors":"Burak Kose, Soley Arslan","doi":"10.1007/s00784-025-06452-9","DOIUrl":"https://doi.org/10.1007/s00784-025-06452-9","url":null,"abstract":"<p><strong>Objective: </strong>This study evaluated the effects of restorations using varied materials and their combinations on cuspal deflection and fracture resistance of endodontically treated MOD cavitated maxillary premolars.</p><p><strong>Materials and methods: </strong>168 premolar teeth were used in the study. The teeth were divided into 14 groups (12 teeth in each group) as Positive control (Group 1), Negative control (Group 2) and Test groups (Group 3-14). MOD cavities were prepared, and then endodontic treatments were performed on teeth in all groups except the positive control group. Group 1 was the Positive control (intact teeth), and Group 2 was the Negative control (only MOD cavity and endodontic treatment). In Groups 3-7 and Groups 9-13, EverX Posterior, SDR Plus Bulk Fill Flowable, G-aenial Universal Injectable, Biodentine, and Fuji II LC were used as the lower layer, respectively. In Groups 3-7, Filtek One Bulk Fill Restorative was used as the upper layer, while in Groups 9-13, Tetric N-Ceram was used. Group 8 was entirely restored with Filtek One Bulk Fill Restorative and Group 14 with Tetric N-Ceram. Cusp deflection was measured. Fracture resistance testing was performed.</p><p><strong>Results: </strong>Within each group, there was a statistically significant decrease in cusp deflection change values at all measured time points (p < 0.05 In the comparison between the groups, cusp deflection change values ​​were found to be significantly higher at all times in the groups where EverX Posterior was applied as the lower layer and Tetric N-Ceram was the upper layer (p < 0.05). In the groups where Filtek One Bulk Fill Restorative was used, differences were seen between the groups at all times (p < 0.05).Groups 4 and 5 exhibited fracture resistance similar to the positive control group (p > 0.05). In the comparison between the groups, a significant increase in fracture resistance was observed in the groups in which only EverX Posterior and SDR Plus Bulk Fill Flowable were applied as the lower layer and the upper layer was Filtek One Bulk Fill Restorative (p < 0.05).</p><p><strong>Conclusions: </strong>Endodontically treated teeth may exhibit different cuspal deflections and fracture resistance when restored with different materials and combinations of these materials.</p><p><strong>Clinical relevance: </strong>When performing coronal restoration of an endodontically treated premolar teeth, it is recommended to select and use the appropriate restorative material, taking into account the position of the tooth in the mouth, cavity dimensions and the amount of material loss.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 8","pages":"380"},"PeriodicalIF":3.1,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144590615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Occlusion, jaw function and nocturnal muscle tone in obstructive sleep apnea with and without sleep bruxism.","authors":"Janine Sambale, Ulrich Koehler, Regina Conradt, Karl Kesper, Werner Cassel, Mikail Degerli, Christian Viniol, Heike Maria Korbmacher-Steiner","doi":"10.1007/s00784-025-06454-7","DOIUrl":"10.1007/s00784-025-06454-7","url":null,"abstract":"<p><strong>Objectives: </strong>Sleep bruxism (SB) is highly prevalent among patients with obstructive sleep apnea (OSA), yet its etiology remains unclear. This prospective clinical trial aimed to evaluate the diagnostic relevance of occlusion, jaw function, and electromyographic (EMG) muscle tone in OSA patients with and without SB.</p><p><strong>Materials and methods: </strong>A total of 105 OSA patients (74 males, 31 females; mean age: 56.1 ± 11.4 years) were assessed, including those with SB and without SB (NSB). Evaluations included occlusal parameters, the Jaw Functional Limitation Scale (JFLS-20), and polysomnography with EMG muscle tone analysis. Descriptive statistics, inter-group comparisons, Spearman's correlation analyses, and Receiver Operating Characteristic (ROC) curve analyses were performed.</p><p><strong>Results: </strong>No significant differences in occlusal parameters were observed between the SB and NSB groups. However, SB patients exhibited significantly higher JFLS-20 scores compared to NSB patients (P = 0.002; mean global score: 20.79 ± 31.96 vs. 6.52 ± 9.70). EMG muscle tone showed significant correlations with JFLS mobility (P = 0.015) and overall jaw function (P = 0.046). ROC curve analysis for EMG muscle tone revealed an Area Under the Curve (AUC) of 0.911 (P < 0.001). An optimal cutoff value of 9.79 µV for EMG muscle tone demonstrated a sensitivity of 78.6% and specificity of 87.9%.</p><p><strong>Conclusion: </strong>EMG muscle tone may serve as a preliminary reference point for differentiating SB from NSB in OSA patients, whereas occlusion lacks diagnostic significance.</p><p><strong>Clinical relevance: </strong>These findings highlight the importance of incorporating functional assessments into the diagnostic workflow for SB in OSA patients. Therapeutic strategies should prioritize functional management rather than occlusal corrections.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 8","pages":"376"},"PeriodicalIF":3.1,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12241266/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144590617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}