Babak Saravi, Veronika Shavlokhova, Ashraf Türky, Daman Deep Singh, Felix Schrader, Andreas Vollmer, Norbert Kübler, Christoph Sproll, Lara Schorn
{"title":"Development and external validation of an AI pipeline for automated estimation of a radiographic DMFT (rDMFT) score from panoramic radiographs: a feasibility study.","authors":"Babak Saravi, Veronika Shavlokhova, Ashraf Türky, Daman Deep Singh, Felix Schrader, Andreas Vollmer, Norbert Kübler, Christoph Sproll, Lara Schorn","doi":"10.1007/s00784-026-07214-x","DOIUrl":"10.1007/s00784-026-07214-x","url":null,"abstract":"<p><strong>Objectives: </strong>To assess the feasibility of estimating a radiographic Decayed-Missing-Filled-Teeth score (rDMFT), a proxy for the clinical DMFT index, from a single panoramic radiograph with a position-aware deep-learning pipeline.</p><p><strong>Materials and methods: </strong>A tooth-status detector and a tooth-numbering detector (32 FDI positions), trained on DENTEX 2023, were combined in a position-aware read-out (one tooth per FDI position, third molars excluded, missing teeth = 28 - occupied positions) and validated on 100 panoramic radiographs from an independent hospital against a two-dentist, radiograph-based reference (intraclass correlation coefficient, ICC; mean absolute error, MAE; Bland-Altman analysis).</p><p><strong>Results: </strong>Against the reference, the pipeline reached an ICC of 0.84 (95% CI 0.74 to 0.90) and an MAE of 2.38, below the between-dentist agreement in point estimate (ICC 0.88, MAE 2.13), with larger errors against each dentist alone (MAE 3.00 and 2.73) and a bias of + 1.14 units from caries over-detection; agreement was highest for filled (r 0.90) and lowest for decayed teeth (r 0.34; dentists 0.16). In the 26 radiographs with missing teeth the missing count was exact in 42% (62% within ± 1 tooth), and missing teeth were over-called in 15 of 74 complete dentitions; tooth loss was no longer overlooked (26 of 26 detected), but the overall ICC was 0.84 versus 0.90 without numbering.</p><p><strong>Conclusions: </strong>Automated rDMFT estimation is feasible, but agreement was lower in point estimate than between two dentists, with larger errors against each dentist. The missing component now responds to actual tooth loss but remains imprecise and is over-called in some complete dentitions; the decayed component is unreliable. The pipeline is a research building block, not a decision-support or triage tool.</p><p><strong>Clinical relevance: </strong>rDMFT is a radiographic proxy, not a clinical measure, and the pipeline is not proposed for clinical use; any application would first require validation in unselected cohorts against clinically determined reference standards.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"30 11","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13669134/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149179900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pedro Diaz, Monica Lopez, Luis J Gil Villagra, Juan Carlos Del Real, Seyed Ali Mosaddad, Maria J Suarez
{"title":"Static and fatigue behavior of one- and two-piece zirconia implant abutment systems: an in vitro study.","authors":"Pedro Diaz, Monica Lopez, Luis J Gil Villagra, Juan Carlos Del Real, Seyed Ali Mosaddad, Maria J Suarez","doi":"10.1007/s00784-026-07219-6","DOIUrl":"https://doi.org/10.1007/s00784-026-07219-6","url":null,"abstract":"<p><strong>Objectives: </strong>To compare static fracture behavior, fatigue survival, and fracture patterns of three one- and two-piece zirconia implant abutment systems.</p><p><strong>Materials and methods: </strong>Three groups comprised 48 assemblies each: (1) Astra Tech ZirDesign, one-piece zirconia; (2) Biomet 3i CAP454, two-piece zirconia with a titanium base; and (3) Straumann RC Anatomic, one-piece zirconia. Within each group, 12 assemblies underwent initial static testing and 12 each underwent fatigue at 25%, 50%, or 75% of the system-specific reference load (10 Hz, approximately 30°, five million cycles). Static outcomes underwent one-way and Welch analyses of variance; pooled run-out proportions underwent exact tests (α = 0.05).</p><p><strong>Results: </strong>Mean static fracture loads were 1058 ± 225 N (Astra Tech), 866 ± 189 N (Biomet 3i), and 873 ± 402 N (Straumann), without a significant difference (p = .194). Calculated tensile-side stress differed (p = .016); compressive-side findings were method-dependent. Run-out was 88.9% at 25% (32/36; 95% confidence interval, 73.9%-96.9%) and 0% at higher levels (p < .001). Residual fracture outcomes described survivors only. Fractography indicated brittle cervical failure.</p><p><strong>Conclusions: </strong>Static fracture-load superiority was not demonstrated. Fatigue run-out varied with relative loading; modeled stress differences do not establish intrinsic material-strength differences.</p><p><strong>Clinical relevance: </strong>These system-specific laboratory results cannot isolate an independent titanium-base effect or establish clinical service life.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"30 11","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149191736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jana Biermann, Angelika Puls, Trixie Heller, Lena Scholz, Lorenz Hein, Annette Wiegand
{"title":"Distinct patterns of caries, erosive tooth wear, and hypomineralization in preschool children: a population-based study of associated factors.","authors":"Jana Biermann, Angelika Puls, Trixie Heller, Lena Scholz, Lorenz Hein, Annette Wiegand","doi":"10.1007/s00784-026-07179-x","DOIUrl":"10.1007/s00784-026-07179-x","url":null,"abstract":"<p><strong>Objectives: </strong>To assess prevalence, severity, and co-occurrence of dental caries, erosive tooth wear (ETW), and hypomineralization in preschool children, and to analyse their associations with general health, developmental, and sociodemographic factors.</p><p><strong>Materials and methods: </strong>This cross-sectional study was conducted within the mandatory school entry examination in Göttingen, Germany. A total of 1,461 children aged 5-6 years underwent standardized dental examinations assessing caries (dft/DFT), ETW (Basic Erosive Wear Examination), and hypomineralization (MIH Treatment Need Index). Information on general health, developmental, and sociodemographic factors was obtained from standardized parental questionnaires and medical assessments conducted as part of the school entry examination. Associations were analysed using multivariable regression models.</p><p><strong>Results: </strong>Caries experience was observed in 29.4% of children and showed a highly polarized distribution. ETW was present in 69.7% of children, generally with low severity. Hypomineralization affected 10.8% of children. No significant associations were found between the three conditions. Caries was strongly associated with migration background, low maternal education, developmental issues, and obesity. ETW showed limited associations, increasing with age and being slightly more severe in boys. Hypomineralization showed no consistent associations.</p><p><strong>Conclusions: </strong>These conditions were common but largely independent and showed differing patterns of association with sociodemographic and health-related factors.</p><p><strong>Clinical relevance: </strong>The largely independent occurrence of these oral conditions suggests that risk assessment and prevention should address them as distinct conditions with differing patterns of association.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"30 11","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13672554/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149191714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Lower intradaily rest-activity variability is associated with severe periodontitis: A cross-sectional wrist-accelerometry study.","authors":"Renjie Huang, Miao Huang, Rui Zhang","doi":"10.1007/s00784-026-07222-x","DOIUrl":"10.1007/s00784-026-07222-x","url":null,"abstract":"<p><strong>Objectives: </strong>Behavioral research on periodontitis has largely emphasized sleep duration and activity volume, whereas the 24-hour temporal organization of movement and rest remains understudied. We examined wrist-accelerometry-derived intradaily variability (IV) in relation to severe periodontitis.</p><p><strong>Materials and methods: </strong>This cross-sectional study included 4,631 adults aged 30 years or older from the National Health and Nutrition Examination Survey 2011-2014. Participants had wrist-accelerometry data and an evaluable full-mouth periodontal examination. Severe periodontitis was defined using the Centers for Disease Control and Prevention/American Academy of Periodontology surveillance definition. Survey-weighted logistic regression with marginal standardization estimated adjusted prevalence measures.</p><p><strong>Results: </strong>Severe periodontitis was identified in 507 participants (survey-weighted prevalence, 7.69%). In the fully adjusted model, standardized prevalence was 7.41% when IV was set to the analytic-cohort mean and 5.83% when IV was set to the mean plus 1 standard deviation. The adjusted marginal prevalence ratio was 0.786 (95% confidence interval, 0.696-0.889), and the prevalence difference was - 1.58% points (95% confidence interval, - 2.32 to - 0.85). Quartile results were broadly inverse but not strictly monotonic, and the restricted cubic spline showed no statistical evidence of nonlinearity.</p><p><strong>Conclusions: </strong>Higher IV was cross-sectionally associated with a lower standardized prevalence of severe periodontitis, although the absolute difference was modest.</p><p><strong>Clinical relevance: </strong>The findings do not establish temporal direction or support clinical intervention; longitudinal studies are needed to determine whether IV adds information beyond established periodontal risk indicators.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"30 11","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149179826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diana Moreira Gomes Martins, Alexia Vaughan Paz, Rafael Bestene de Oliveira Dos Santos, Mariana Tenório Picanço, Ricardo Roberto de Souza Fonseca, Milton Carlos Kuga, Mileide da Paz Brito, Cristiane de Melo Alencar
{"title":"Bioactive oral gels containing Libidibia ferrea and Brazilian propolis preserve the mechanical and mineral properties of eroded human enamel.","authors":"Diana Moreira Gomes Martins, Alexia Vaughan Paz, Rafael Bestene de Oliveira Dos Santos, Mariana Tenório Picanço, Ricardo Roberto de Souza Fonseca, Milton Carlos Kuga, Mileide da Paz Brito, Cristiane de Melo Alencar","doi":"10.1007/s00784-026-07215-w","DOIUrl":"10.1007/s00784-026-07215-w","url":null,"abstract":"<p><strong>Objectives: </strong>To develop polyphenol-rich oral gels containing Libidibia ferrea or Brazilian brown propolis extracts and evaluate their effects on the mechanical and mineral properties of human enamel subjected to erosive-abrasive challenges.</p><p><strong>Materials and methods: </strong>Experimental gels containing L. ferrea (0.5% and 2.5%) or Brazilian brown propolis (0.5% and 2.5%) were formulated and evaluated for physicochemical properties, antioxidant activity, stability, and cytocompatibility. Seventy-two human enamel specimens were randomly assigned to six groups (n = 12): control gel, 0.5% and 2.5% L. ferrea gels, 0.5% and 2.5% propolis gels, and a commercial stannous fluoride toothpaste. Specimens underwent a 7-day erosive-abrasive cycling model. Surface microhardness, surface roughness, enamel crystallinity, phosphate-to-carbonate ratio, and color variation were assessed. Data were analyzed using ANOVA and Tukey's test (α = 0.05).</p><p><strong>Results: </strong>All formulations exhibited near-neutral pH and satisfactory cytocompatibility. Stability was maintained under refrigeration, whereas color changes and precipitate formation occurred during storage at room and elevated temperatures. Following the erosive-abrasive challenge, the 2.5% L. ferrea and 2.5% propolis gel groups showed higher final surface microhardness, lower percentage surface microhardness loss, and lower final surface roughness than the other treatment groups (p < 0.05). Raman spectroscopy showed lower full width at half maximum values for the phosphate ν₁ band and higher phosphate-to-carbonate ratios in the 2.5% L. ferrea and 2.5% propolis gel groups than in the other groups (p < 0.05).</p><p><strong>Conclusions: </strong>Oral gels containing 2.5% L. ferrea or Brazilian brown propolis showed promising protective effects on human enamel under the in vitro erosive-abrasive conditions tested.</p><p><strong>Clinical relevance: </strong>These gels are promising candidates for erosive tooth wear prevention, pending in situ and clinical validation addressing color changes and concentration-dependent stability.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"30 11","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13661705/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149179640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yeon-Hee Lee, Seonggwang Jeon, Do-Hoon Kim, Sunyoung Kim, Tae-Seok Kim, Sang-Woo Lee, Yung-Kyun Noh
{"title":"Xerogenic medications and clinical markers of salivary hypofunction.","authors":"Yeon-Hee Lee, Seonggwang Jeon, Do-Hoon Kim, Sunyoung Kim, Tae-Seok Kim, Sang-Woo Lee, Yung-Kyun Noh","doi":"10.1007/s00784-026-07184-0","DOIUrl":"10.1007/s00784-026-07184-0","url":null,"abstract":"<p><strong>Objectives: </strong>To determine whether xerogenic medication-class exposure and chair-side salivary markers contribute to risk stratification of objective salivary hypofunction across a broad clinical age spectrum, using conventional regression and explainable machine-learning approaches.</p><p><strong>Materials and methods: </strong>This retrospective cross-sectional study included 850 patients (mean age, 60.8 ± 15.6 years; 657 [77.3%] female) who underwent salivary flow assessment and oral clinical evaluation at Kyung Hee University Dental Hospital. Patients were categorized into four age groups: <40, 40-64, 65-79, and ≥ 80 years. Unstimulated salivary flow rate (UFR), stimulated salivary flow rate (SFR), and flow-rate-defined hyposalivation were analyzed using age-group comparisons, multivariable regression models, incremental gradient boosting models, and SHapley Additive exPlanations (SHAP)-based model interpretation.</p><p><strong>Results: </strong>Mean UFR was significantly lower in older age groups, ranging from 0.57 ± 0.30 mL/min in patients aged < 40 years to 0.36 ± 0.24 mL/min in those aged ≥ 80 years (p < 0.001), whereas age-group differences in SFR were less pronounced. SFR-defined hyposalivation was most frequent in the ≥ 80-year group (17.3%; p = 0.007). In adjusted models, the ≥ 80-year group had lower UFR than the < 40-year group (β = -0.194; 95% CI, - 0.272 to - 0.115; p < 0.001) and higher odds of SFR-defined hyposalivation (OR = 5.47; 95% CI, 1.44-20.78; p = 0.013). Female sex was associated with lower UFR (β = -0.055; p = 0.009) and SFR (β = -0.369; p < 0.001). High-confidence xerogenic medication-class count was independently associated with SFR-defined hyposalivation (OR = 1.63; 95% CI, 1.12-2.36; p = 0.010). In incremental machine-learning models, adding salivary pH and buffer capacity produced the largest improvement in discrimination. AUROC increased from 0.468 to 0.723 for UFR-defined hyposalivation (ΔAUROC = 0.255; DeLong p < 0.001) and from 0.608 to 0.725 for SFR-defined hyposalivation (ΔAUROC = 0.116; DeLong p = 0.005). SHAP analysis ranked salivary buffer capacity as the leading contributor for both outcomes, with salivary pH also among the top predictors.</p><p><strong>Conclusions: </strong>Objective salivary hypofunction was not fully explained by age, systemic disease burden, or medication burden alone. Instead, chair-side salivary functional markers, particularly salivary pH and buffer capacity, captured clinically relevant information about current salivary status. These findings support a practical, layered approach to identifying patients who may require objective salivary flow assessment.</p><p><strong>Clinical relevance: </strong>Chair-side salivary pH and buffer capacity may help clinicians identify patients who warrant objective salivary flow assessment, particularly when considered together with age, sex, and xerogenic medication-class exposure.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"30 11","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13661656/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149179835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Allograft versus xenograft for alveolar ridge preservation in non-molar extraction sockets: a systematic review and meta-analysis of randomized controlled trials.","authors":"Bala Karthiga V, Shruti Tandon, Arundeep Kaur Lamba, Farrukh Faraz","doi":"10.1007/s00784-026-07218-7","DOIUrl":"10.1007/s00784-026-07218-7","url":null,"abstract":"<p><strong>Objectives: </strong>To compare the clinical, radiographic, and histological outcomes of allograft and xenograft materials used for alveolar ridge preservation following non-molar tooth extraction through a systematic review and meta-analysis of randomized controlled trials.</p><p><strong>Materials and methods: </strong>This systematic review and meta-analysis was conducted in accordance with the PRISMA 2020 guidelines and registered in PROSPERO (CRD420261333947). Electronic searches of PubMed/MEDLINE, the Cochrane Central Register of Controlled Trials (CENTRAL), and ClinicalTrials.gov were performed through May 2026. Randomized controlled trials directly comparing allograft and xenograft materials for alveolar ridge preservation in non-molar extraction sockets were included. Risk of bias was assessed using the revised Cochrane Risk of Bias (RoB 2) tool. A qualitative synthesis and random-effects meta-analysis were performed where appropriate.</p><p><strong>Results: </strong>Seven randomized controlled trials met the inclusion criteria, of which three were included in the meta-analysis. Both allograft and xenograft materials were associated with preservation of alveolar ridge dimensions following tooth extraction, although clinical and radiographic findings did not demonstrate a consistent advantage of either material. Histological findings suggested greater new bone formation, fewer residual graft particles, and faster graft remodeling with allografts, whereas xenografts were associated with slower resorption and greater persistence of residual graft particles. Meta-analysis demonstrated no statistically significant difference between allografts and xenografts in buccal height loss (SMD = - 0.177; 95% CI: -1.822 to 1.468; p = 0.833), with substantial heterogeneity (I² = 82%).</p><p><strong>Conclusions: </strong>Current evidence does not demonstrate a consistent clinical or radiographic superiority of either allograft or xenograft for alveolar ridge preservation following non-molar tooth extraction. Although biological differences in graft remodeling were observed, the limited number of studies, small sample size, and substantial heterogeneity reduce the certainty and precision of these findings. The absence of a statistically significant difference should not be interpreted as evidence of equivalence between the two materials. Further well-designed randomized controlled trials with standardized outcome measures and longer follow-up are needed to strengthen the available evidence.</p><p><strong>Clinical relevance: </strong>Available evidence does not demonstrate a consistent clinical or radiographic advantage of either allograft or xenograft for preservation of alveolar ridge dimensions following non-molar tooth extraction. The findings may assist clinicians in considering graft material selection for alveolar ridge preservation based on clinical requirements, while recognizing the limited and heterogeneous evidence and the absence of ","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"30 11","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149179453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Does dental bleaching really damage restorations - or are we measuring the wrong outcomes?","authors":"Diogo de Azevedo Miranda, Rafael Rocha Pacheco","doi":"10.1007/s00784-026-07220-z","DOIUrl":"10.1007/s00784-026-07220-z","url":null,"abstract":"","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"30 11","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149179845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bryan D Murchie, David Lynch, Andrew Carr, David Edwards
{"title":"Defining progression in erosive tooth wear: an interpretive challenge.","authors":"Bryan D Murchie, David Lynch, Andrew Carr, David Edwards","doi":"10.1007/s00784-026-07217-8","DOIUrl":"10.1007/s00784-026-07217-8","url":null,"abstract":"<p><strong>Objectives: </strong>To critically evaluate current approaches to longitudinal erosive tooth wear (ETW) monitoring and examine whether quantitative intraoral scanner (IOS)-based measurements and conventional clinical indices can be meaningfully compared in defining progression.</p><p><strong>Materials and methods: </strong>A systematic review identified longitudinal studies evaluating ETW using IOS-based quantitative approaches alongside conventional clinical assessment methods. MEDLINE, Embase, Scopus, and Web of Science were searched from database inception to January 2026, with grey literature sources also searched. The electronic database searches were updated in August 2026 using the original search strategies. Reference-list screening and forward citation tracking were undertaken alongside both the initial search and the updated search.</p><p><strong>Results: </strong>Five longitudinal studies met the eligibility criteria. IOS-based approaches consistently detected measurable surface change over time, including during relatively short follow-up intervals in which conventional clinical indices frequently demonstrated no categorical progression. Substantial heterogeneity existed in progression thresholds, outcome measures, superimposition methodologies, and reporting strategies. Agreement between IOS-derived measurements and conventional index scores was variable and generally weak to moderate. IOS quantifies continuous dimensional change, whereas clinical indices categorise severity using ordinal scales. No validated framework was identified linking quantified dimensional surface loss to clinically meaningful ETW progression.</p><p><strong>Conclusions: </strong>Quantitative IOS measurements and conventional clinical indices assess different dimensions of tooth wear and cannot currently be interpreted as directly interchangeable measures of progression. Validated frameworks linking quantitative surface loss to biological and clinical relevance are required.</p><p><strong>Clinical relevance: </strong>IOS enables high-resolution longitudinal quantification of tooth surface change, but the clinical significance of detected change remains uncertain. Establishing clinically meaningful progression thresholds is essential for integrating quantitative digital monitoring into routine care.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"30 11","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13661733/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149179759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on \"prevalence of caries in teeth adjacent to implant-supported prostheses and relationship with implant location and the manner of restoration placement: a retrospective cohort study\".","authors":"T K Vidhya, G Arundhathi, Sam Jebaraj","doi":"10.1007/s00784-026-07144-8","DOIUrl":"10.1007/s00784-026-07144-8","url":null,"abstract":"","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"30 11","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149179806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}