Clinical Oral Investigations最新文献

{"title":"Efficacy of artificial saliva in preventing oral changes in patients admitted to the ICU: a controlled clinical trial.","authors":"Edmundo Duarte Martins, Nayara Isabelle Cabral Rebouças, Sophia Queiroz Marques Dos Santos, Tatiana Bernardo Farias Pereira, Rosângela Oliveira da Câmara, Maria do Rosário Avelino Bezerra Silva, Alzira Maria Batista Guará, Ana Clara Guedes Queiroz, Addison Ribeiro de Almeida, Leandro De Santis Ferreira, Ericka Janine Dantas da Silveira","doi":"10.1007/s00784-026-06864-1","DOIUrl":"https://doi.org/10.1007/s00784-026-06864-1","url":null,"abstract":"","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"30 5","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13106235/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147764539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Voltage-tunable plasma-activated water: a strategy for combating peri-implantitis via dual-path biofilm disruption and vascular regeneration.","authors":"Yiyuan Lang, Han Mei, Jingyun Zhang, Chenxi Hu, Zixu Pang, Yan Chen, Changao Xue","doi":"10.1007/s00784-026-06749-3","DOIUrl":"https://doi.org/10.1007/s00784-026-06749-3","url":null,"abstract":"","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"30 5","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147764627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-surgical root canal treatments in a public dental service: Characteristics of patients, teeth and operators from a 16-year register-based study.","authors":"Milo Väisänen, Ulla Palotie, Jussi Furuholm, Battsetseg Tseveenjav","doi":"10.1007/s00784-026-06876-x","DOIUrl":"https://doi.org/10.1007/s00784-026-06876-x","url":null,"abstract":"","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"30 5","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13109112/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147764603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Wisdom teeth removal and anterior alignment stability after orthodontic treatment-a systematic review.","authors":"Sophia Amberg, Annika Kroeger, Emma Houlston, Sinan Şen, Moritz Kebschull","doi":"10.1007/s00784-026-06872-1","DOIUrl":"https://doi.org/10.1007/s00784-026-06872-1","url":null,"abstract":"","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"30 5","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13109118/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147764567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison between patient-specific implants and hand-bent plates in mandibular reconstruction.","authors":"Max Lukas Linderkamp, Efthymios Papazacharias, Thomas Lewandowski, Stephan Alexander Bettag, Jörg Mast, Fritjof Lentge, Philipp Jehn, Michael-Tobias Neuhaus, Nils-Claudius Gellrich, Philippe Korn","doi":"10.1007/s00784-026-06875-y","DOIUrl":"https://doi.org/10.1007/s00784-026-06875-y","url":null,"abstract":"<p><strong>Objectives: </strong>Alloplastic reconstruction is often required following segmental mandibular resection (SMR). Hardware-associated complications, especially hardware fractures, almost invariably necessitate explantation. Recent advances in manufacturing techniques promise potential advantages over traditional methods, including increased fracture resistance. However, to date, there is no scientific evidence confirming whether these benefits translate to real-life clinical conditions.</p><p><strong>Materials and methods: </strong>A total of 210 patients underwent SMR followed by alloplastic reconstruction between 2007 and 2019 at Hannover Medical School. The indications for SMR were tumor (n = 208; n = 196 squamous cell carcinoma) and osteoradionecrosis (n = 2). The mean patient age was 60.61 years, with a range of 14 to 89 years. The cohort comprised 146 male patients (69.52%) and 64 female patients (30.48%). Of these, 113 patients underwent reconstruction using hand-bent reconstruction plates (RP), while 97 received patient-specific implants (PSI). The incidence of hardware-related complications (HRC) was compared between the RP and PSI groups.</p><p><strong>Results: </strong>HRC occurred in 72 cases (34.29%). Exposure of the implant accounted for 47 cases (22.38%) while fractures occurred in 18 cases (8.57%), showing no significant difference between PSI and RP. Time from diagnosis until resection and reconstruction was not delayed due to the use of PSI.</p><p><strong>Conclusions: </strong>The choice of alloplastic manufacturing method does not affect HRC rates. PSI is offering benefits beyond fracture resistance and does not delay SMR.</p><p><strong>Clinical relevance: </strong>HRC remain challenging and may additionally impair patients' quality of life. In particular, hardware fractures often necessitate additional surgical interventions, underlining the need to identify the factors that contribute to their occurrence. To the best of the author's knowledge, this is the largest cohort study comparing RP and PSI with respect to HRC.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"30 5","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13106252/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147764155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness and influencing factors of strip-cushioning transcrestal sinus floor elevation: a clinical retrospective study.","authors":"Chen Deng, Chenyu Rao, Weie Song, Yaxin Xing, Chen Hu, Yi Man","doi":"10.1007/s00784-026-06893-w","DOIUrl":"https://doi.org/10.1007/s00784-026-06893-w","url":null,"abstract":"","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"30 5","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147764491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: Comparison of injectable platelet-rich fibrin, titanium platelet-rich fibrin, and 0.8% hyaluronic acid applications versus periodontal dressing alone in wound healing after gingivectomy and gingivoplasty operations: randomized controlled clinical study.","authors":"Özlem Saraç Atagün, Şeyma Çardakci Bahar, Seval Ceylan Şen, Gülbahar Ustaoğlu, Erkan Özcan, Zeynep Cansu Güzel, Merve Inceöz","doi":"10.1007/s00784-026-06887-8","DOIUrl":"https://doi.org/10.1007/s00784-026-06887-8","url":null,"abstract":"","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"30 5","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13106244/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147764474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microbiome in adult severe caries and cross-kingdom biofilms validation.","authors":"Liuliu Jiang, Yifei Tang, Lu Xu, Yuan Wei, Miaomiao Liu, Xiaoxuan Che, Ranran Xin, Yanan Zhu","doi":"10.1007/s00784-026-06878-9","DOIUrl":"https://doi.org/10.1007/s00784-026-06878-9","url":null,"abstract":"<p><strong>Objectives: </strong>Adult severe caries (ASC) is a form of rampant caries that develops in adulthood, causing severe impairment of oral function and reducing quality of life. However, the pathogenic mechanism of ASC remains unclear. This study aimed to identify the core microbiota in patients with ASC and preliminarily investigate the microbial interactions and pathogenicity of key ASC-associated core microorganisms.</p><p><strong>Materials and methods: </strong>Saliva samples were collected from 7 adult patients with severe caries and 6 caries-free volunteers for metagenomic analysis. Based on microbiome profiling results, an in vitro cross-kingdom biofilm model composed of Streptococcus mutans (S. mutans), Candida albicans (C. albicans) and Veillonella parvula (V. parvula) was established to simulate a high caries-risk microenvironment. Scanning electron microscopy (SEM), crystal violet (CV) staining, and live/dead bacterial staining were used to evaluate biofilm formation. Acid production assays, acid stress challenge tests, confocal laser scanning microscopy (CLSM) and qRT-PCR were performed to analyze the acidogenicity and synthesis of extracellular polysaccharides (EPS). Additionally, atomic force microscopy (AFM) was used to assess the surface roughness of demineralized dentin slices.</p><p><strong>Results: </strong>Metagenomic analysis revealed significant enrichment of C. albicans and V. parvula in the saliva of patients with high caries susceptibility. The in vitro cultured cross-kingdom biofilms exhibited enhanced growth and EPS synthesis compared with single-species S. mutans biofilms. Moreover, cross-kingdom biofilms significantly increased surface roughness of demineralized samples, with a stronger effect than single- and dual-species biofilms.</p><p><strong>Conclusions: </strong>Colonization by C. albicans and V. parvula increases biofilm biomass, enhances microbial survival under stress, and elevates biofilm virulence, which induces demineralization of dentin slices in vitro.</p><p><strong>Clinical relevance: </strong>This study demonstrates that the interspecies interactions among caries-related microorganisms in ASC patients confer enhanced virulence and cariogenicity, providing novel insights for the investigation and prevention of high caries susceptibility.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"30 5","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147764460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Automated detection of C-shaped canals in mandibular second molars from panoramic radiographs: comparing single and ensemble convolutional neural networks within a 2-stage pipeline.","authors":"Yunus Emre Çakmak, Kürşat Er","doi":"10.1007/s00784-026-06868-x","DOIUrl":"https://doi.org/10.1007/s00784-026-06868-x","url":null,"abstract":"","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"30 5","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13102809/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147764046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced efficacy of oral hygiene instructions during motivational interviewing using intraoral scanner technology: a randomized clinical trial.","authors":"Jacopo Lanzetti, Federica Ferrati, Armando Crupi, Umberto Gibello, Andrea Roccuzzo, Francesco Pera","doi":"10.1007/s00784-026-06867-y","DOIUrl":"https://doi.org/10.1007/s00784-026-06867-y","url":null,"abstract":"","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"30 5","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147764481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}