Clinical Oral Investigations最新文献

{"title":"Marginal adaptation analysis of CAD/CAM resin crown with non-invasive methods.","authors":"Chen Zeng, Tomoko Tabata, Rena Takahashi, Masaomi Ikeda, Junichi Shinagawa, Hisaichi Nakagawa, Yumi Tsuchida, Shunsuke Takano, Yasunori Sumi, Yasushi Shimada","doi":"10.1007/s00784-025-06215-6","DOIUrl":"10.1007/s00784-025-06215-6","url":null,"abstract":"<p><strong>Objectives: </strong>This study compared the silicone replica method with swept-source optical coherence tomography (SS-OCT) to analyze marginal adaptation and investigated the effect of the light incidence angle of SS-OCT on measurement precision.</p><p><strong>Materials and methods: </strong>A typodont-prepared mandibular right first molar was scanned using an intraoral scanner (Trios 3). Fourteen crowns were fabricated from CAD/CAM resin blocks (Katana Avencia P) using a 5-axis milling machine (DWX-50). Marginal adaptation at the buccal, lingual, mesial, and distal points was assessed using the silicone replica method and SS-OCT at light incidence angles of 60°, 75°, and 90°. Statistical comparisons were performed using two-way analysis of variance (ANOVA) and t-tests with Bonferroni correction, and t-tests at a significance level of 0.05.</p><p><strong>Results: </strong>At 60°, SS-OCT showed significantly larger marginal discrepancies than the silicone replica method at the buccal, lingual, and mesial points (p < 0.05). At 75°, only the lingual point showed a significantly larger value than the silicone replica method (p < 0.05). At 90°, no significant differences were observed between the SS-OCT and silicone replica methods (p > 0.05). Marginal discrepancy values increased as the angle changed from 90° to 75° to 60°, with significant differences between 60° and 75° and between 60° and 90° at the buccal and lingual points (p < 0.05).</p><p><strong>Conclusions: </strong>SS-OCT is a viable alternative to the silicone replica method for assessing marginal adaptation at an incidence angle of 90 °.</p><p><strong>Clinical relevance: </strong>SS-OCT, a non-invasive method, has the potential to be applied clinically for evaluating marginal fit in indirect restorations in vivo.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 3","pages":"158"},"PeriodicalIF":3.1,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11861017/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143499717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of volumetric and surface stability of calcium silicate-based repair cements at different pHs.","authors":"Ana Cristina Padilha Janini, Débora Leticia Bittencourt Leite Alves, Victor Augusto Benedicto Dos Santos, Brenda Fornazaro Moraes, Nilvan Alves da Silva, Matheus Barros-Costa, Luciano Augusto Cano Martins, Francisco Haiter Neto, Marina Angélica Marciano","doi":"10.1007/s00784-025-06232-5","DOIUrl":"https://doi.org/10.1007/s00784-025-06232-5","url":null,"abstract":"<p><strong>Objectives: </strong>The objective of this research was to evaluate the volumetric and surface stability in vitro, to different pH levels, of calcium silicate-based repair cements ready-to-use and powder/liquid exposed.</p><p><strong>Materials and methods: </strong>Sixty human teeth were retro-prepared to a depth of 3 mm and divided into two groups. The first group included powder/liquid cements Biodentine (Septodont, France) and MTA HP (Angelus, Brazil); the second group included ready-to-use cements Bio-C Repair (Angelus, Brazil) and ENDOCEM MTA (Maruchi, Republic of Korea). All samples were submerged in PBS solution with pH levels of 5, 7, and 12. Initially, the materials were evaluated for porosity, marginal adaptation, and volumetric change using micro-CT, and then re-evaluated after 7 and 30 days of exposure to PBS solution. The samples were characterized using SEM/EDS and RAMAN spectroscopy. Statistical evaluation was performed using ANOVA with a 5% significance level.</p><p><strong>Results: </strong>Bio-C Repair showed significant statistical differences (p < 0.05) at different pHs in 7 and 30 days compared to other materials, being greater in acidic medium. ENDOCEM, regardless of pH, at 30 days showed fewer voids when compared to other repair cements.</p><p><strong>Conclusion: </strong>This micro-CT study demonstrated that regardless pH, the clinic presentation of calcium silicate-based materials ready-to-use showed higher and loss volumetric than powder/liquid materials at 30 days.</p><p><strong>Clinical relevance: </strong>Under neutral pH conditions, calcium silicate-based materials are expected to maintain properties such as bioactivity and low solubility. However, in clinical situations involving infection and inflammation, pH variations can impact the physicochemical properties of these materials regardless of their clinical presentation.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 3","pages":"160"},"PeriodicalIF":3.1,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143499716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Are dental professionals aware of the discovery of newly identified salivary glands? Is there a debate about this discovery?","authors":"Ahmet Eren Karabıyık, Tuna Sumer, Kübra Çam, Sibel Uçak Semirgin, Ayşe Zeynep Zengin","doi":"10.1007/s00784-025-06228-1","DOIUrl":"https://doi.org/10.1007/s00784-025-06228-1","url":null,"abstract":"<p><strong>Aim: </strong>Writing a letter to the editor.</p><p><strong>Background: </strong>Saliva plays a crucial role in chewing, swallowing, digestion, taste, and oral hygiene. In addition to the three major salivary glands in humans (parotid, submandibular, and sublingual glands), the existence of small salivary glands scattered in the submucosa of the nasopharynx and oropharynx is also known.</p><p><strong>Material and methods: </strong>Is it a new organ? This discovery has attracted significant attention from the scientific community but has also raised questions and sparked debates. Should the tubarial glands be classified as major or minor salivary glands, or as a separate organ? For a structure to be classified as an organ, it must have a distinct shape and structure, consist of multiple tissue types, and perform specific functions.</p><p><strong>Conclusion: </strong>As we know, the definition and recognition of an organ must be based on scientific foundations. More research is needed on tubarial glands, and it seems that this discussion will continue for some time. Our purpose in writing this letter is to raise awareness of this issue among dental professionals.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 3","pages":"161"},"PeriodicalIF":3.1,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143514870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The normal width of the lateral incisors in the maxilla in an European population.","authors":"Irene Artioli, Aline Ndayisaba, Jean-Pierre Ndayisaba, Adriano Giacomo Crismani","doi":"10.1007/s00784-025-06235-2","DOIUrl":"10.1007/s00784-025-06235-2","url":null,"abstract":"<p><strong>Objectives: </strong>Dental anomalies are clinical alterations that originate during the tooth formation process. This prospective study aims to establish the norm and hypoplasia values for maxillary lateral incisors. Additionally, it aims to describe the relationship between the width of the lateral and the central incisors, considering gender, age, and body height.</p><p><strong>Materials and methods: </strong>The first 103 consecutive patients meeting the inclusion criteria were included in the study. The upper jaw of each patient was scanned, and the scans were saved as standard tessellation language (STL) files. The upper incisors of each digital cast were measured on the computer. Two examiners performed the same measurements independently.</p><p><strong>Results: </strong>The average size of the maxillary central incisor was 8.59 ± 0.51 mm, while the average size of the maxillary lateral incisor was 6.64 ± 0.46 mm. A formula describing a relationship between the central (x) and lateral (y) incisors was defined with a linear regression analysis y = 1.88 + 0.55 * x. Width of maxillary incisors [11, 12, 21, 22] increased with height (p = 0.028, p = 0.016, p = 0.016, p = 0.046 respectively).</p><p><strong>Conclusions: </strong>Hypoplasia of the maxillary lateral incisor can be defined for teeth with a mesiodistal width less than 6.18 mm in a patient that is represented with the test group. A relationship between the maxillary lateral incisors and central incisors could have been established by means of a formula.</p><p><strong>Clinical relevance: </strong>The width of the maxillary lateral incisors allows a precise orthodontic and prosthetic planning.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 3","pages":"159"},"PeriodicalIF":3.1,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11860988/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143499722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of biocorrosion and titanium ions release on peri-implantitis.","authors":"Chonghao Ji, Yaqian Chen, Misi Si, Xiaoyan Chen","doi":"10.1007/s00784-025-06186-8","DOIUrl":"https://doi.org/10.1007/s00784-025-06186-8","url":null,"abstract":"<p><strong>Objectives: </strong>Biofilm accumulation is considered the primary cause of peri-implant inflammation. Still, metallosis caused by an increased concentration of titanium ions at the site of peri-implantitis site cannot be ignored. Whether titanium ions alone or in concert with bacterial biofilm trigger inflammation and bone destruction in peri-implant tissues remains unproven.</p><p><strong>Materials and methods: </strong>Articles were retrieved from PubMed/Medline, Web of Science. All studies focusing on titanium ions release in peri-implant reactions were included and evaluated.</p><p><strong>Results: </strong>Titanium implants are considered non-inert and may release titanium ions in the intraoral microenvironment, the most important of which is the acidic environment created by bacterial biofilms. Although the correlation between titanium ion release and the incidence or progression of peri-implantitis is controversial, several studies have confirmed the potential role of titanium ions. Diffusion or entry of titanium ions into the circulation may be a scavenging effect on local titanium ions but can cause systemic adverse effects. However, existing measures are not yet able to balance reducing biocorrosion and maintaining osteogenic results, and the exploration of new materials requires long-term clinical data.</p><p><strong>Conclusions: </strong>Titanium ions have potential impacts on peri-implant tissue and systemic circulation. Titanium ions are closely associated with bacterial biofilms in the occurrence and development of periimplantitis. The preventive strategies for the release and action of titanium ions remain to be explored.</p><p><strong>Clinical relevance: </strong>Our findings may provide the hope of shedding light on the pathogenesis of peri-implantitis and its treatment.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 3","pages":"155"},"PeriodicalIF":3.1,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143491173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Discriminating bacterial types in oral and maxillofacial space infections (OMSIs) via smelling diagnosis.","authors":"Rui Ren, Xue Jiang, Shanluo Zhou, Haiqiang Li, Qiang Niu, Danyao Qu, Ruizhi Ning, Zerou Zhang, Liang Kong, Weiwei Wu, Yunpeng Li","doi":"10.1007/s00784-025-06243-2","DOIUrl":"https://doi.org/10.1007/s00784-025-06243-2","url":null,"abstract":"<p><strong>Objectives: </strong>To explore the feasibility of using gas chromatography-mass spectrometry (GC-MS) in the diagnosis of bacterial types of oral and maxillofacial space infections (OMSIs).</p><p><strong>Methods: </strong>Staphylococcus aureus was cultured to produce a full spectrum of volatile organic compounds (VOCs). These VOCs were collected and identified using VOC collectors and GC-MS. A bacteria Probability-based VOC Algorithm (BPVA) was developed to assess the likelihood of infection in vivo utilizing a rat model. VOCs from 19 clinical OMSIs abscess samples were analyzed to calculate the probability of SA infection, with results validated against traditional culture results.</p><p><strong>Results: </strong>Using fold change (FC), p-values (P), and variable importance in projection (VIP) values, we identified 318 characteristic target compounds associated with Staphylococcus aureus. After fitting these compounds to the rat infection model, 189 compounds were selected, establishing a BPVA threshold of ≥ 50, with a 95% probability of consistency. Four patients exhibited an SA infection probability exceeding 70%, whereas the other patients fell below this threshold. Clinical results confirmed SA infections in these four patients, with detection times reduced to approximately 24 h, significantly shorter than the typical 3-5 days.</p><p><strong>Conclusions: </strong>The combination of GC‒MS and BPVA significantly accelerated the diagnosis of bacterial types in OMSIs, demonstrating strong agreement with traditional culture results, highlighting a new method to accurately and rapidly diagnose maxillofacial infections.</p><p><strong>Clinical relevance: </strong>Rapid identification of bacterial types is essential for treating OMSIs. However, current bacterial culture methods face challenges, such as limited accuracy and time-consuming processes.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 3","pages":"157"},"PeriodicalIF":3.1,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143491201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In-vitro validation of a new method to assess the clinical accuracy of complete arch impressions.","authors":"Moritz Waldecker, Schessler Katherina, Bömicke Wolfgang, Rammelsberg Peter, Rues Stefan","doi":"10.1007/s00784-025-06236-1","DOIUrl":"10.1007/s00784-025-06236-1","url":null,"abstract":"<p><strong>Objectives: </strong>To develop and validate a new method to acquire reference distances.</p><p><strong>Materials and methods: </strong>A method to accurately register the intraoral position of precision balls was developed to generate reference values for the in-vivo assessment of impression accuracy and tested in vitro. Therefore, metal occlusal veneers with a special abutment carrying precision balls were provisionally attached to specific positions on the patient's dental arch (anatomical model with PMMA covered metal teeth). To register the precision ball positions, form-congruent counterparts were jointed to the abutments, adhesively fixed to a transfer aid, removed and digitized with a laboratory scanner. First, the distance determination using a transfer aid and a laboratory scanner was validated. Second, the process was tested for an anatomic situation.</p><p><strong>Results: </strong>When measuring distances using a transfer aid and a laboratory scanner, distances could be detected with an accuracy of less than 5 μm. Using the new test setup on the anatomical model, the intraoral scanners more accurately reproduced scan volumes up to one quadrant, with deviations between the actual scan data sets/plaster models and the reference data set of < 52 μm for Primescan, < 82 μm for Omnicam, and < 125 μm for conventional impression. Longer distances tended to be more accurately represented by the conventional impression (Primescan < 304 μm; Omnicam < 328 μm; conventional impression < 164 μm).</p><p><strong>Conclusions: </strong>The developed method seems suitable for determining the clinical accuracy of conventional and digital complete arch impressions.</p><p><strong>Clinical relevance: </strong>For determining the clinical accuracy of conventional or digital impressions, reference values are crucial.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 3","pages":"156"},"PeriodicalIF":3.1,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11861410/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143491202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the overall fit of three-unit posterior fixed dental prostheses fabricated with laser sintering and conventional casting methods.","authors":"Gürel Pekkan, Kubra Degirmenci, Süleyman Hakan Tuna, Canan Hekimoğlu, Serkan Saridag","doi":"10.1007/s00784-025-06221-8","DOIUrl":"10.1007/s00784-025-06221-8","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of this study was to investigate the marginal, internal, and occlusal discrepancies of three-unit posterior cobalt-chromium (Co-Cr) fixed dental prostheses (FDPs) produced using five different fabrication techniques.</p><p><strong>Materials and methods: </strong>Segmental maxillary models were prepared from polyamide material using a laser sintering method. The maxillary first premolar and first molar teeth were prepared to receive posterior FDPs. Direct metal laser sintering (DMLS) and selective laser melting (SLM) were used as two metal laser Co-Cr framework production systems. FDP specimen patterns were prepared by manual wax carving (Cast), 3D-printed polymer (3DP), and CAD/CAM wax and cast using the lost-wax technique as conventional methods. In total, 100 Co-Cr metal framework specimens were prepared for posterior FDPs (n = 20). The silicone replica technique was used to measure marginal, internal, and occlusal discrepancies of all frameworks. A stereomicroscope was employed to detect discrepancies at 100× magnification. The data were analyzed using two-way ANOVA (α = 0.05) and post hoc Bonferroni adjustment (α = 0.005) for pairwise comparisons.</p><p><strong>Results: </strong>There were no significant differences between the occlusal discrepancy values of premolar abutments of FDPs when compared with different fabrication methods (P > 0.05). The highest marginal discrepancy value was detected as 116.22 μm for molar abutment when the Cast method was used (P < 0.05). The highest occlusal discrepancy values were detected as 135.60 μm and 141.49 μm for molar abutments of posterior FDPs when the 3DP and Cast methods were used. The lowest marginal discrepancy value was detected as 38.94 μm for molar abutments when the DMLS method was used (P < 0.05).</p><p><strong>Conclusions: </strong>The DMLS method was more successful than other fabrication methods when fit values of abutment teeth for posterior frameworks were compared.</p><p><strong>Clinical relevance: </strong>The morphology of the abutment teeth and the fabrication techniques of FDPs migth affect the discrepancy values of FDPs planned. It was seen that the discrepancy values were lowest with the DMLS and SLM methods. Considering the results of this in-vitro study, DMLS and SLM techniques may be more appropriate option than the 3DP method, which starts with digital design and ends conventionally casting technique for posterior three-unit FDPs.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 3","pages":"153"},"PeriodicalIF":3.1,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11847754/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143482273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Polishing of 4Y- and 5Y- zirconia: effects on roughness, color and gloss.","authors":"Laura Koch, Sebastian Hahnel, Angelika Rauch, Martin Rosentritt","doi":"10.1007/s00784-025-06244-1","DOIUrl":"10.1007/s00784-025-06244-1","url":null,"abstract":"<p><strong>Objectives: </strong>To investigate the effects of polishing systems on the roughness, gloss and color of two zirconia materials as a function of the rotational speed and number of polishing movements.</p><p><strong>Materials and methods: </strong>Specimens (n = 8/group) from 4Y-TZP and 5Y-TZP were milled, diamond grinded and polished. The intraoral polishing varied in the number of polishing steps, the grain size and the matrix. Different number of polishing movements and rotation speed were used. Roughness (ISO25178-2:2021), gloss (ISO2813:2014) and color stability (ISO/CIE 11664-4:2019) were determined.</p><p><strong>Statistics: </strong>Shapiro-Wilk, one-way analysis, Bonferroni, Pearson, variance analysis/intermediate sub-effects (α = 0.05).</p><p><strong>Results: </strong>Roughness Sa varied between 2.45 ± 0.93 µm and 6.47 ± 0.26 µm (4Y-TZP) and 2.31 ± 0.19 µm and 6.54 ± 0.22 µm (5Y-TZP). Maximum roughness Sz ranged from 32.92 ± 12.59 µm to 99.32 ± 19.87 µm (4Y-TZP) and 31.45 ± 3.02 µm to 90.75 ± 12.59 µm (5Y-TZP). Different gloss from 28.9 ± 4. 23 to 102.39 ± 18.63 GU (4Y-TZP) and 33.19 ± 3.68 to 101.28 ± 10.00 GU (5Y-TZP) was found. ΔE results ranged from 0.39 ± 0.34 to 6.30 ± 1.22 (4Y-TZP) and 0.87 ± 0.71 to 7.50 ± 1.67 (5Y-TZP). Significant (p ≥ 0.095) intermediate sub-effects were found.</p><p><strong>Conclusions: </strong>Polishing led to a reduction in roughness, an increase in gloss and a significant change in color. Polishing had a stronger effect on 5Y-TZP.</p><p><strong>Clinical relevance: </strong>The correct use of the polisher type (stages, binder) and its specific application (rotational speed, movements) can improve roughness, gloss and color variations.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 3","pages":"154"},"PeriodicalIF":3.1,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11850485/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143482280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CBCT image based radiomic analysis for condylar resorption after orthognathic surgery.","authors":"Ruo-Han Ma, Ji-Ling Feng, Jia-Yang Chen, Yu-Xuan Yang, Ju-Peng Li, Gang Li","doi":"10.1007/s00784-025-06227-2","DOIUrl":"https://doi.org/10.1007/s00784-025-06227-2","url":null,"abstract":"<p><strong>Objectives: </strong>To select and discover features which are highly correlated with condylar resorption (CR) after orthognathic surgery (OS) by a new method.</p><p><strong>Materials and methods: </strong>The cone beam computed tomography (CBCT) images were collected from orthognathic patients taken at T1(baseline time point) and T2(within 3-36 months postoperatively). The subjects were divided into the CR group and the control group by using a 2-level scale after registering T1 and T2 images. The condyles were segmented by MVEL-Net network model and were analyzed by Pyradiomics. The D-value equaled to the absolute difference-value (D-value) between the feature values of T1 and T2. The correlation between features with statistically significant differences in T1 and D-values would be analyzed to find the specific features related to CR after OS.</p><p><strong>Results: </strong>A total of 145 subjects were included (27 males and 118 females), which had 44 subjects in the CR group, 101 subjects in the control group. For all samples, a total of 82 features were extracted (F₁), which were with statistical differences at T1 time point between CR and control groups. By using the D-value, the number of features was reduced to 32 features (F_d). Among F_d, only 3 were not included in F₁.</p><p><strong>Conclusions: </strong>The D-value was proposed for selecting specific features of CR after OS and it can be observed that the D-value serves the purpose of feature specification compared to T1 values. By using the D-values, several features were found to change significantly during the process of CR after OS.</p><p><strong>Clinical relevance: </strong>The features selected by D-value can be used for the establishment of a prediction model for CR after OS.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 3","pages":"152"},"PeriodicalIF":3.1,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143476343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}