Clinical Oral Investigations最新文献

{"title":"Bactericidal nanotopography of titanium dental implants: in vitro and in vivo studies.","authors":"Javier Gil, Mariano Sanz","doi":"10.1007/s00784-025-06424-z","DOIUrl":"10.1007/s00784-025-06424-z","url":null,"abstract":"<p><strong>Objective: </strong>A new passivation method for titanium dental implants has been studied, where the nanotextured layer features spikes that provide a high bactericidal capacity without compromising the degree of osseointegration of the dental implants.</p><p><strong>Materials and methods: </strong>This layer has been obtained through a sulfuric acid treatment with hydrogen peroxide. It has been characterized using electron microscopy, the roughness was determined by confocal microscopy and wettability and surface energy assessed through contact angle. The incorporation of hydrogen was assessed using a fusion spectrometer. Fatigue behavior was evaluated with a servo-hydraulic testing machine. The adhesion of human osteoblastic cells SaOs-2 at 3 and 7 days was measured, and the level of mineralization was analyzed by alkaline phosphatase levels. Bacterial colonization assays were conducted using four strains to assess their bactericidal capacity. Implants were inserted into rabbit tibiae. After 21 days, the animals were sacrificed, and bone index contact determined.</p><p><strong>Results: </strong>A uniform surface created by nanospikes was obtained, exhibiting the same roughness as the control implant, no hydrogen was incorporated inside the titanium. The fatigue behavior showed no variation compared to the control. An increased wettability and higher surface energy compared to the control implant were noted. Enhanced osteoblastic adhesion was observed for the nanospikes surface in comparison with control at 3 days, with a significant level of alkaline phosphatase at 14 days, indicating a good degree of mineralization. The bactericidal capacity of nanospike surface is evidenced showing reductions ranging from 70 to 90%. In vivo tests demonstrate higher bone contact index values for dental implants with nanospikes (56%) compared to the control (41%).</p><p><strong>Conclusions: </strong>The surface formed by nanospikes maintains the mechanical properties of the control and improves the wettability of the surface which improves the behavior of the osteoblasts generating a better osseointegration. At the same time, it has a high bactericidal capacity that prevents microbiological colonization.</p><p><strong>Clinical relevance: </strong>Peri-implantitis has become one of the major problems for the success of implant dentistry and this new surface may be a solution for the prevention of the disease.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 7","pages":"351"},"PeriodicalIF":3.1,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12198065/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144483414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vitality tests for pulp diagnosis of adjacent teeth following sinus floor elevation: a prospective study.","authors":"Jochen Tunkel, Shengchi Fan, Anita Kloss-Brandstätter, Frank R Kloss, Henning Staedt, Frederic Kauffmann, Diana Heimes, Peer W Kämmerer","doi":"10.1007/s00784-025-06440-z","DOIUrl":"10.1007/s00784-025-06440-z","url":null,"abstract":"<p><strong>Objectives: </strong>The Schneiderian membrane is elevated to place bone graft material during sinus floor augmentation. Since the teeth's vascular and neurovascular supply passes through the maxillary sinus, this procedure may lead to sensitivity loss in adjacent teeth. This study is the first to prospectively analyze the vitality of adjacent teeth after sinus floor elevation.</p><p><strong>Materials and methods: </strong>Data were collected between 2015 and 2023 from 158 patients, who underwent maxillary sinus floor augmentation and implant placement. A total of 378 teeth were examined for vitality using cold testing at the following time points: (1) before sinus floor elevation, (2) 2 weeks, (3) 4 months, (4) 8 months, and (5) 12 months post-surgery. Follow-up duration ranged from 12 to 32 months.</p><p><strong>Results: </strong>Two teeth in two patients showed no vitality before surgery, but became vital postoperatively. In 3 teeth (0.79%), pulp vitality loss was recorded 2 weeks after surgery, which was restored at the 4-month follow-up. These teeth remained vital after one year. The pre-and postoperative pulp vitality comparison showed no statistically significant difference (p = 0.625).</p><p><strong>Conclusions: </strong>This first prospective observational study demonstrated that a few patients experienced temporary pulp sensitivity loss immediately post-surgery, which resolved within four months.</p><p><strong>Clinical relevance: </strong>Pulp sensitivity loss due to vascular disruption during sinus floor augmentation is rare and usually temporary. Despite potential vascular disruption, sinus floor augmentation procedures do not appear to cause permanent pulp sensitivity loss.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 7","pages":"350"},"PeriodicalIF":3.1,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12198307/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144483420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: Performance of a novel direct-conversion intraoral sensor on the assessment of caries-like lesions- an ex-vivo comparison with conventional (scintillator-dependent) intraoral sensors.","authors":"Juliana B Melo da Fonte, Daniela Pita de Melo, Ana Paula Piovezan Fugolin, Saulo L Sousa Melo","doi":"10.1007/s00784-025-06446-7","DOIUrl":"10.1007/s00784-025-06446-7","url":null,"abstract":"","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 7","pages":"349"},"PeriodicalIF":3.1,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144474092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel sleeveless guided system for reducing thermal injury in endodontic microsurgery with enhanced accuracy and efficiency.","authors":"Moran Jin, Rentao Tang, Zeqian Pan, Yuhan Wang, Zuhua Wang, Bing Han, Xiaoyan Wang","doi":"10.1007/s00784-025-06433-y","DOIUrl":"https://doi.org/10.1007/s00784-025-06433-y","url":null,"abstract":"<p><strong>Objectives: </strong>This study evaluated surgical temperature, accuracy, and efficiency in endodontic microsurgery (EMS) using the sleeveless guided system.</p><p><strong>Materials and methods: </strong>Sleeveless and sleeve guided systems were fabricated. Thermocouples were used to measure temperature changes during guided preparation in models (n = 5) featuring bone blocks installed in anterior, premolar, and molar regions. 72 teeth in 6 EMS models used for simulating the clinical scenario of endodontic microsurgery were equally randomized into 6 groups by guide type (sleeveless/sleeve/freehand) and operator experience, with each group containing matched dentition (2 anterior/2 premolar/2 molar teeth per arch; n = 12). Preoperative and postoperative models were superimposed using 3-matic Medical evaluate preparation accuracy, with surgical duration compared for efficiency. Temperature data were analyzed via t-test; accuracy and efficiency were assessed using two-way ANOVA.</p><p><strong>Results: </strong>The sleeveless guided system demonstrated significantly lower surgical area temperatures than the sleeve guided system (P < 0.001). Compared to freehand, it reduced three-dimensional (3D) deviation by 1.14 mm (52.8%), angular deviation by 4.06° (49.6%), and surgical time by 40.5 s (P < 0.05). When using sleeveless system, experienced operators exhibited reductions of 0.65 mm in 3D deviation and 4.51° in angular deviation, whereas inexperienced operators demonstrated larger reductions of 1.96 mm and 5.79° respectively. No significant differences were observed between guide systems in accuracy or efficiency (P > 0.05).</p><p><strong>Conclusion: </strong>The sleeveless guided system effectively reduces heat generation and enhances surgical accuracy and efficiency compared to freehand techniques significantly, with performance comparable to the sleeve guided system.</p><p><strong>Clinical relevance: </strong>The sleeveless guided system demonstrates promising applications in EMS.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 7","pages":"347"},"PeriodicalIF":3.1,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144474090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive 3D measurements of condyle changes in patients with class III asymmetry after bimaxillary orthognathic surgery.","authors":"Chi Zhang, Yule Xu, Yuxiang Wei, Yuan Li, Songsong Guo, Hongbing Jiang, Dongmiao Wang, Jie Cheng","doi":"10.1007/s00784-025-06432-z","DOIUrl":"https://doi.org/10.1007/s00784-025-06432-z","url":null,"abstract":"<p><strong>Objectives: </strong>The present study was aimed to assess three-dimensional (3D) quantitative changes of condyle in patients with Class III facial asymmetry after bimaxillary orthognathic surgery.</p><p><strong>Materials and methods: </strong>Fifty-five eligible patients with Class III facial asymmetry received Le Fort I osteotomy and bilateral sagittal split osteotomy (BSSO) with or without genioplasty from January 2020 to June 2022 were included. Cone-beam computed tomography (CBCT) for each patient was collected at 3 stages: 1 week preoperatively (T0), immediately after surgery (T1) and at least 12 months postoperatively (T2). Positional changes and bone remodeling of condyles were measured based on voxel- and surface-registrations using ITK-SNAP and 3D Slicer and compared between various stages. Correlations between these changes, mandibular surgical movements and skeletal stability were further explored.</p><p><strong>Results: </strong>Most condyles at deviated side (DS) tended to shift inferiorly, anteriorly and to non-deviated side (NDS), while condyles at NDS were displaced posteriorly, inferiorly and laterally from T0 to T1. Condyles showed upward pitch, outward yaw and lateral roll at both sides. Bone resorption was more frequently observed in the posterior area of condylar surface at NDS. Significant correlations were found between mandibular anteroposterior/transverse stability and DS condylar lateral shift or NDS condylar yawing after surgery (T1-T2), respectively.</p><p><strong>Conclusions: </strong>Our results comprehensively characterize 3D condylar changes and their associations with skeletal stability after surgical correction of Class III facial asymmetry.</p><p><strong>Clinical relevance: </strong>These findings advance current understanding of complex condylar changes after bimaxillary orthognathic surgery in Class III facial asymmetry patients.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 7","pages":"348"},"PeriodicalIF":3.1,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144474091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of non-surgical periodontal therapy on gingival crevicular fluid CTRP-1, TNF-α, and IL-10 levels.","authors":"Asena Kadayıf, Özge Elif Taşçi, Burcu Karaduman","doi":"10.1007/s00784-025-06420-3","DOIUrl":"10.1007/s00784-025-06420-3","url":null,"abstract":"<p><strong>Objectives: </strong>This study investigated the gingival crevicular fluid (GCF) levels of complement-C1q tumor necrosis factor related protein-1 (CTRP-1), tumor necrosis factor-α (TNF-α), and interleukin-10 (IL-10) following non-surgical periodontal therapy (NSPT) in systemically healthy individuals with periodontal health (H), generalized gingivitis (G), and stage III grade B periodontitis (P). Moreover, this study aimed to investigate their diagnostic potential in distinguishing different periodontal diseases.</p><p><strong>Materials and methods: </strong>73 systemically healthy non-smoking individuals were divided into H (n = 25), G (n = 23) and P (n = 25) groups. Clinical periodontal parameters were recorded, and GCF samples were collected at baseline in all groups, and 3rd month after NSPT in the G and P groups. GCF levels of CTRP-1, TNF-α, and IL-10 were analyzed using ELISA. The area under the curve (AUC) was assessed using the receiver operating characteristic curve analysis.</p><p><strong>Results: </strong>CTRP-1 levels were significantly elevated in the G and P group compared to the H group (p < 0.001), while there was no significant difference between the G and P groups (p = 0.095). TNF-α and IL-10 levels were significantly higher in the P group compared to the other groups (p < 0.001). GCF CTRP-1 demonstrated an excellent diagnostic performance to discriminate periodontitis and gingivitis from periodontal health (AUC value of 0.998 and 0.974 with 100% and 91.3% sensitivity).</p><p><strong>Conclusion: </strong>CTRP-1 could serve as a potential biomarker for periodontal diseases. CTRP-1 demonstrated excellent diagnostic performance in distinguishing stage III grade B periodontitis and gingivitis from periodontal health.</p><p><strong>Clinical relevance: </strong>GCF CTRP-1 levels may serve as a valuable marker for diagnosing periodontal diseases.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 7","pages":"345"},"PeriodicalIF":3.1,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12182460/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144339886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The potential of resolvin D2 loaded hydroxyapatite/mineral trioxide aggregate electrospun membranes to downregulate Interleukin 1 beta and tumor necrosis factor alpha in human dental pulp stem cells and macrophages co-cultures.","authors":"Soumya Sheela, Fatma Mousa AlGhalban, Khalil Abdelrazek Khalil, Vellore Kannan Gopinath","doi":"10.1007/s00784-025-06426-x","DOIUrl":"10.1007/s00784-025-06426-x","url":null,"abstract":"<p><strong>Objective: </strong>To develop electrospun polycaprolactone (PCL) membranes incorporating Hydroxyapatite/Mineral Trioxide Aggregate (HAp/MTA) loaded with Resolvin D2 (RvD2) and evaluate its anti-inflammatory potential.</p><p><strong>Method: </strong>Electrospun membranes were fabricated by blending PCL with 10 wt.% HAp/10 wt.% MTA loaded with or without 0.1% RvD2 and were characterized using Field Emission Scanning Electron Microscopy (FE-SEM), energy-dispersive X-ray (EDX) spectroscopy, Raman spectroscopy, contact angle measurements, and RvD2 release.</p><p><strong>Results: </strong>The field emission scanning microscopy (FE-SEM) showed uniform nanofibers with an average fiber diameter ranging from 300 to 600 nm. Energy-dispersive X-ray (EDX) analysis and Raman spectroscopy confirmed the presence of HAp and MTA in the PCL membranes. The drug release profile displayed a rapid release of RvD2 initially, followed by a sustained release. XTT assay demonstrated the cytocompatibility of the membranes towards the THP-1-derived M1 macrophages and human dental pulp stem cells (hDPSCs) co-cultures activated with LPS. The FE-SEM studies proved the favorable cell adhesion behaviour although the membranes being hydrophobic. Cytokine levels in the culture supernatants retrieved from the co-culture treated membranes showed that, of all the membranes, RvD2 incorporated PCLHAp/MTA membranes demonstrated reduced IL-1β and TNF-α production.</p><p><strong>Conclusions: </strong>RvD2 incorporated PCLHAp/MTA membranes demonstrated reduced IL-1β and TNF-α production asserting its anti-inflammotory potential.</p><p><strong>Clinical significance: </strong>This research highlights the immunomodulatory effect of RvD2-loaded PCLHAp/MTA electrospun membranes in reducing inflammation of the dental pulp. This novel method has the potential to transform the treatment of dental pulp inflammation resulting from caries or injury.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 7","pages":"346"},"PeriodicalIF":3.1,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144339887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of laser and sonic activated irrigation on obturation quality in conservatively prepared mandibular molars: a micro-CT analysis.","authors":"Megan Yamaguchi, Ane Poly, Alexander Huynh, Poorya Jalali","doi":"10.1007/s00784-025-06373-7","DOIUrl":"https://doi.org/10.1007/s00784-025-06373-7","url":null,"abstract":"<p><strong>Introduction: </strong>The objective of this study was to compare the quality of obturation in the mesial roots of mandibular molars with isthmuses, using Er, Cr: YSGG laser and sonic-activated irrigation, assessed by micro-CT scanning.</p><p><strong>Methods: </strong>Mesial canals of extracted mandibular molars were instrumented to a master apical file size of 20/V06. The final irrigation protocol included 2.5% NaOCl, 17% EDTA, and a final rinse with 2.5% NaOCl, applied with either sonic-activated or laser-activated irrigation using the WaterLase iPlus (BIOLASE, Inc, Foothill Ranch, CA). Canals were obturated with Bioceramic Sealer HiFlow (Brasseler, Savannah, GA) and gutta-percha cones. Micro-computed tomography scans were obtained before and after obturation to evaluate the quality of obturation, determined by the percentage of unfilled spaces in each irrigation group.</p><p><strong>Results: </strong>There was no statistically significant difference in baseline canal characteristics, including isthmus width, canal volume, root curvature, and Weine classification between the groups (p > 0.05). In the post-obturation evaluation with micro-CT, the mean percentage of unfilled spaces was higher in the sonic group (17.24%) than in the laser group (10.73%), showing a statistically significant difference (p < 0.05).</p><p><strong>Conclusions: </strong>This study suggests that laser-activated irrigation may improve the quality of obturation in mandibular molars with isthmuses compared to sonic-activated irrigation.</p><p><strong>Clinical significance: </strong>This study demonstrates that laser-activated irrigation can lead to a higher quality of obturation in conservatively instrumented canals by reducing the percentage of unfilled spaces. However, these findings should be cautiously interpreted, as the improved obturation quality observed may not directly translate to clinical outcomes. Further research is needed to determine if this advanteg influence long-term treatment success.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 7","pages":"344"},"PeriodicalIF":3.1,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144324667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of CAD/CAM titanium fixed lingual retainer versus conventional stainless steel fixed retainer (randomized controlled clinical trial).","authors":"Nada E A Elhosseiny, Wessam M Marzouk, Mostafa A Tageldin","doi":"10.1007/s00784-025-06418-x","DOIUrl":"10.1007/s00784-025-06418-x","url":null,"abstract":"","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 7","pages":"343"},"PeriodicalIF":3.1,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12174219/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144315985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accuracy of intraoral scans of the edentulous maxilla - an in vitro study.","authors":"Panagiotis Kontis, Jan-Frederik Güth, Christine Keul","doi":"10.1007/s00784-025-06419-w","DOIUrl":"10.1007/s00784-025-06419-w","url":null,"abstract":"<p><strong>Objective: </strong>Investigation of the accuracy of various digitalization methods and the accuracy of digitalization of different regions of the edentulous maxilla.</p><p><strong>Material and method: </strong>A PEEK edentulous maxilla with four spherical reference geometries served as the testing model. A reference dataset (REF) was generated using a highly accurate 3D measuring instrument. The testing model was digitized as follows (n = 25/group). Direct digitalization (DD) with intraoral scanners (IOS): 1) Cerec AC Primescan (PRI), 2) Trios 4 Move (TR4), 3) Trios 3 Wireless (TR3), 4) Indirect digitalization of PVS impression with laboratory scanner 3Shape D810 (D8I). Three-dimensional deviations between REF and TEST were evaluated (GOM Inspect) in different areas of the model: 1) Complete Surface, 2) Alveolar Ridge, 3) Vestibular Ridge, 4) Palate, 5) Posterior Seal, 6) Border. Significant differences were analyzed with the Games-Howell test for trueness (p < 0.05) and multiple comparisons Levene's test for precision (for IOS: p < 0.008, for area: p < 0.003).</p><p><strong>Results: </strong>Group D8I revealed the best trueness for Complete Surface (7.95 µm), Palate (9.11 µm), and Border (20.22 µm). Alveolar Ridge showed for PRI (16.45 µm) and TR4 (8.96 µm) the highest trueness. Groups TR4 and PRI resulted in significantly higher precision for Alveolar Ridge. Groups TR4 and D8I demonstrated the highest precision for Palate. Complete Surface and Alveolar Ridge showed for all digitalization methods significantly higher precision.</p><p><strong>Conclusions: </strong>Indirect digitalization of impressions remains the most accurate approach for capturing edentulous jaws, whereas IOS deliver datasets with clinically acceptable accuracy. Peripheral regions characterized by limited accessibility and smooth surface morphology tend to demonstrate increased deviations in the resulting digital datasets.</p><p><strong>Clinical relevance: </strong>Indirect digitalization of the impression still appears to be the most appropriate technique to access the clinical workflow for full dentures due to the superior digitalization trueness and inclusion of functional movements. Direct and indirect digitalization show nearly equal values for precision.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 7","pages":"342"},"PeriodicalIF":3.1,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12170734/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144309658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}