Clinical Oral Investigations最新文献

{"title":"Effects of slow maxillary expansion on perioral muscle pressure and parafunctions in children: a prospective study.","authors":"Charlotte Van de Walle, Stefanos Vichos, Giacomo Begnoni, Anna Verdonck, Guy Willems, Maria Cadenas de Llano-Pérula","doi":"10.1007/s00784-025-06436-9","DOIUrl":"10.1007/s00784-025-06436-9","url":null,"abstract":"<p><strong>Aim: </strong>To investigate the effect of Slow Maxillary Expansion (SME) on Maximum Tongue, Lip, and left and right Cheek Pressure (MTP, MLP, MCP), with the aim to identify possible correlations with dental characteristics and parafunctions.</p><p><strong>Materials and methods: </strong>Patients with mixed dentition presenting crossbite, lack of space in the upper jaw and/or a mandibular shift were included. Digital casts were analysed and perioral muscle pressure was assessed using the Iowa Oral Performance Instrument before (T₀), after active expansion (T₁) and at the end of treatment (T₂). Additionally, parafunctions were assessed.</p><p><strong>Results: </strong>136 children were included. SME significantly increased arch length, intermolar and intercanine distance and reduced upper anterior crowding. Sagittal molar relationship and overbite improved. MTP and MCP increased significantly at T₁ and T₂, while MLP remained unchanged. A negative correlation was observed between MLP and intermolar and intercanine distances whose significance did not maintain after correction for multiple testing. Nail/pen biting and mouth breathing decreased significantly during and after treatment. The presence of lip interposition led to higher MLP and left MCP, also non-significant after correction.</p><p><strong>Conclusion: </strong>SME with removable appliances in mixed dentition leads to significant short-term improvement of dentoalveolar characteristics, increasing MTP and MCP and reducing the presence of parafunctions such as nail/pen biting and mouth breathing. No substantial correlation was observed between muscle pressure changes and dental changes, suggesting the latter to be primarily attributed to the appliance itself.</p><p><strong>Clinical relevance: </strong>SME in mixed dentition leads to myofunctional adaptation and has a positive effect on parafunctions.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 7","pages":"363"},"PeriodicalIF":3.1,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144526705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sense of coherence buffers the burden of dental caries and gingivitis on quality of life during pregnancy.","authors":"Maiara de Carvalho Segatto, Gabriela de Araujo, Sabrina Cabral Pacheco, Jessica Klöckner Knorst, Fernanda Tomazoni, Bruno Emmanuelli","doi":"10.1007/s00784-025-06438-7","DOIUrl":"10.1007/s00784-025-06438-7","url":null,"abstract":"","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 7","pages":"362"},"PeriodicalIF":3.1,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144526706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: Clinical outcome and technical complications of bimaxillary fullarch implantsupported Metalresin Fxed dental prostheses with or without ceramic molars: 5year results.","authors":"Stefan Krennmair, Michael Weinländer, Lukas Postl, Michael Malek, Thomas Forstner, Helfried Hulla, Gerald Krennmair","doi":"10.1007/s00784-025-06448-5","DOIUrl":"10.1007/s00784-025-06448-5","url":null,"abstract":"","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 7","pages":"361"},"PeriodicalIF":3.1,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12205013/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144505049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of thermal aging on the color matching of Class III and Class V restorations with universal resin composites in various-shade human teeth: an instrumental and visual evaluation.","authors":"Seyit Bilal Ozdemir, Busra Ozdemir","doi":"10.1007/s00784-025-06439-6","DOIUrl":"10.1007/s00784-025-06439-6","url":null,"abstract":"<p><strong>Objectives: </strong>This in vitro study aimed to assess the color matching of two single-shade and one group-shade universal composite resins for Class III and Class V restorations in extracted human teeth of different shades and evaluate the impact of thermal aging on these restorations using both instrumental and visual methods.</p><p><strong>Materials and methods: </strong>Forty-five extracted human central incisors in a range of Vita Classical shades (A1, A2 and A3) were used. Three composite resins (Zenchroma (ZC), Charisma Diamond One (CDO), and Neo Spectra ST (NEO)) were tested. Each tooth received both Class III and Class V restorations (2 mm depth and 4 mm diameter) with the same composite resin. Color measurements were made immediately after restoration, 24 h, and after thermal aging using an intraoral spectrophotometer. Color differences (ΔE₀₀) were calculated using the CIEDE2000 formula. Visual assessments were scored from 0 (perfect fit) to 4 (significant mismatch) by three dental specialist. Data were analyzed using IBM SPSS V23. A Generalized Linear Model (GLM) was used to assess main and interaction effects, and Tukey's test was applied for multiple comparisons. A significance level of p < 0.05 was considered.</p><p><strong>Results: </strong>NEO showed statistically significantly lower ΔE₀₀ values (2.45 ± 1.29) compared to the other composite resins (p < 0.001). Class III restorations (3.41 ± 1.48) exhibited lower ΔE₀₀ values than Class V restorations (4.56 ± 2.23, p < 0.001). ΔE₀₀ values decreased after aging (p = 0.007).</p><p><strong>Conclusion: </strong>Class III restorations demonstrated better color matching than Class V restorations in both visual and instrumental evaluations. The group-shade composite resin showed better color matching compared to the single-shade composite resins. Although visual matching improved over time, some instrumentally measured color differences remained above the clinically acceptable threshold (ΔE₀₀>1.8).</p><p><strong>Clinical relevance: </strong>Clinicians should consider both composite type and cavity configuration when selecting materials for aesthetic restorations.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 7","pages":"360"},"PeriodicalIF":3.1,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12202620/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144495024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The in vitro antibacterial efficacy of advanced platelet-rich fibrin plus supplemented with metronidazole against Fusobacterium nucleatum.","authors":"Anh-Truc Huynh-Pham, Son Hoang Le, Bich-Ly Thi Nguyen","doi":"10.1007/s00784-025-06431-0","DOIUrl":"10.1007/s00784-025-06431-0","url":null,"abstract":"<p><strong>Purpose: </strong>Owing to its high antibacterial efficacy and low adverse effects, local antibiotic administration has attracted attention. This in vitro study compares the antibacterial effectiveness of advanced platelet-rich fibrin plus (A-PRF+) combined with metronidazole produced under different protocols.</p><p><strong>Materials and methods: </strong>Eight volunteers participated in this study. A 0.02% metronidazole was supplemented into A-PRF + based on four protocols concerning time (before vs. after centrifugation) and dosages (0.25 vs. 0.50 mL), yielding four groups: B25 (before centrifugation, 0.25 mL), B50 (before centrifugation, 0.50 mL), A25 (after centrifugation, 0.25 mL), and A50 (after centrifugation, 0.50 mL). Agar diffusion experiments on Fusobacterium nucleatum strain ATCC 25,586 were conducted to determine the bacterial efficacy of the four groups on three time points: day 2 (D2), D3 and D4. Images of the bacterial inhibition zone (BIZ) at assessment times were captured to measure BIZ dimensions using ImageJ software.</p><p><strong>Results: </strong>No significant difference was found between the BIZs of B25 and B50; however, the BIZs of A50 were significantly higher than those of A25. BIZs of each group tend to decrease, although no significant difference was found. Two-way repeated measures ANOVA revealed a significant interaction between the timing and observation time points. Post-hoc analysis showed that at each observation time point, BIZs of A-PRF + combined with metronidazole after centrifugation were significantly higher than those before, regardless of the dosage.</p><p><strong>Conclusion: </strong>The results of this study suggest that supplementing metronidazole into A-PRF + after centrifugation provides better antibacterial efficacy against Fusobacterium nucleatum than before centrifugation.</p><p><strong>Clinical relevance: </strong>A-PRF + supplemented with metronidazole after centrifugation can exert better antibacterial efficacy against Fusobacterium nucleatum.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 7","pages":"359"},"PeriodicalIF":3.1,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144495025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of fluocinolone acetonide, ProRoot MTA and their combination on inflammation and odontogenic differentiation of inflamed human dental pulp cells.","authors":"Suphachart Chayawatto, Chatvadee Kornsuthisopon, Pairoj Linsuwanont","doi":"10.1007/s00784-025-06380-8","DOIUrl":"10.1007/s00784-025-06380-8","url":null,"abstract":"<p><strong>Objectives: </strong>To compare the effect of fluocinolone acetonide (FA), mineral trioxide aggregate (MTA), and their combination on inflamed human dental pulp cells (HDPCs), focusing on cell viability, expression of inflammation and mineralisation-associated genes, and odontogenic differentiation.</p><p><strong>Methods: </strong>HDPCs were treated with 20 µg/mL lipopolysaccharide (LPS) alone or in combination with and 400 µM hydrogen peroxide (H₂O₂) for 6, 12, 24 and 48 h to induce inflammatory conditions. Normal and inflamed HDPCs were further treated with FA, MTA extraction medium, or a combination of MTA and FA. Cell viability was assessed using a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. The expression of inflammatory and mineralisation-associated genes was evaluated by reverse transcription-quantitative polymerase chain reaction (RT-qPCR). Odontogenic differentiation was determined by alkaline phosphatase staining (ALP) and alizarin red S staining (ARS).</p><p><strong>Results: </strong>HDPCs pretreated with LPS and H₂O₂ had reduced cell viability, increased expression of IL-1β and IL-6, decreased expression of ALP and DSPP, and reduced odontogenic differentiation. Treatment with FA alone or in combination with MTA improved these parameters, except for odontogenic differentiation, which was enhanced only in the FA-treated group.</p><p><strong>Conclusion: </strong>FA exerted anti-inflammatory properties and promoted odontogenic differentiation under the inflammatory milieus of HDPCs in this in vitro study.</p><p><strong>Clinical relevance: </strong>Under the simulated inflammatory condition of HDPCs, this in vitro study suggests the potential benefit of FA for anti-inflammatory and mineralisation enhancing properties.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 7","pages":"358"},"PeriodicalIF":3.1,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144495023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the effect of intracanal cryotherapy on postoperative pain after retreatment: a randomized controlled clinical trial.","authors":"Arzu Kaya Mumcu, Ecenur Tuzcu, Safa Kurnaz, Gülsen Kiraz","doi":"10.1007/s00784-025-06435-w","DOIUrl":"10.1007/s00784-025-06435-w","url":null,"abstract":"","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 7","pages":"355"},"PeriodicalIF":3.1,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12198275/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144483419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the antibacterial activity, surface microhardness, and color change of glass ionomer cement containing green synthesized Ag@MoS₂ nanocomposite after thermal aging.","authors":"Semiha Ekrikaya, Ozcan Karatas, Ebubekir Yilmaz, Nilay Ildiz, Seyma Dadi, Derya Gamze Sahin, Melih Ucar, Ismail Ocsoy","doi":"10.1007/s00784-025-06437-8","DOIUrl":"10.1007/s00784-025-06437-8","url":null,"abstract":"<p><strong>Objective: </strong>The aim of our study is to compare the antibacterial activity, surface microhardness, and color change of glass ionomer cement (GIC) with the addition of green-synthesized silver nanoparticles (Ag NP) and silver molybdenum disulfide (Ag@MoS₂) nanocomposites (NC) after thermal aging conditions.</p><p><strong>Methods: </strong>Our study consisted of five groups (n = 7): only GIC (control); GIC + Green-synthesized Ag NP; GIC + Green-synthesized Ag@MoS₂ NC; GIC + Chemically synthesized Ag NP, and GIC + Chemically synthesized Ag@MoS₂ NC. The nanoparticles were synthesized, characterized using the required protocols, and added to the liquid part of the GIC. Disk-shaped samples with a diameter of 10 mm and a thickness of 2 mm were prepared with the nanoparticle-mixed GIC and used to determine the S. mutans live/dead assay analysis, MTT metabolic activity test, agar disk diffusion test, lactic acid production, and CFUs values. The microhardness and color change of the samples were evaluated, and statistical analysis was performed (α = 0.05).</p><p><strong>Results: </strong>Statistically significant differences were observed between the experimental and the control groups regarding live bacteria ratio, lactic acid production, inhibition zone, CFUs, and S. mutans metabolic activity (p < 0.05). The highest antibacterial efficacy in the experimental groups was observed in the Ag@MoS₂ NC groups. The addition of Ag NP and Ag@MoS₂ NC synthesized by green and chemical methods did not adversely affect the microhardness or cause clinically significant changes in the color of the experimental GICs (p > 0.05). Thermal aging did not adversely affect the obtained results.</p><p><strong>Conclusion: </strong>Adding Ag NP and Ag@MoS₂ NC to GICs may provide sufficient antibacterial efficacy without adversely affecting color or microhardness values even after thermal aging.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 7","pages":"354"},"PeriodicalIF":3.1,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12198296/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144483418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative clinical performance of universal adhesives versus etch-and-rinse and self-etch adhesives: a meta-analysis.","authors":"Matheus Polesso Patias, Paula Fernandes-E-Silva, Neftali Lenin Villareal Carreño, Rafael Guerra Lund, Evandro Piva, Adriana Fernandes da Silva, Wellington Luiz De Oliveira Da Rosa","doi":"10.1007/s00784-025-06427-w","DOIUrl":"10.1007/s00784-025-06427-w","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the clinical performance of universal adhesives (UA) in different modes in direct dental resin composite restorations compared to control self-etch and etch-and-rinse adhesives.</p><p><strong>Materials and methods: </strong>The study is reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA). A literature search was performed in five databases (Pubmed, Web of Science, Embase, Scopus, and Cochrane) until August 2024. Only RCTs that compared retention, marginal staining, and postoperative sensitivity of different forms of application of UA with etch-and-rinse and self-etching adhesives were included. The meta-analysis was performed using the Revman software (Cochrane Collaboration, UK), and this review was preregistered with the PROSPERO (CRD42022314408).</p><p><strong>Results: </strong>A total of 15 RCTs were included, with a follow-up varied from 6 months to 4 years. In the global analysis, considering three outcomes, UA were statistically similar to control adhesives (etch-and-rinse and self-etch) regardless of the mode of application (ER, SE or EE), with a risk difference of -0.01 (-0.04, 0.02; p = 0.43; I² = 45%) for retention, -0.02 (-0.05, 0.01; p = 0.32; I² = 27%) for marginal discoloration and 0.00 (-0.01, 0.01; p = 0.82; I² = 0%) for postoperative sensitivity.</p><p><strong>Conclusion: </strong>Universal adhesives had similar clinical performance to conventional ER and SE adhesives.</p><p><strong>Clinical relevance: </strong>Universal adhesives provide clinical performance comparable to conventional etch-and-rinse and self-etch adhesives, offering a simplified and effective option for adhesive procedures.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 7","pages":"352"},"PeriodicalIF":3.1,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144483415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of laser applications with different agents on dentin surface roughness, bacterial adhesion and tubule occlusion.","authors":"Ayşe Dündar, Kaan Yılmaz, Çağatay Barutçugil, Özlem Koyuncu Özyurt","doi":"10.1007/s00784-025-06443-w","DOIUrl":"10.1007/s00784-025-06443-w","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate the effects of laser application with different agents on dentin surface roughness, tubule occlusion, and bacterial adhesion in vitro.</p><p><strong>Materials and methods: </strong>A total of 216 dentin blocks from bovine incisors were divided into nine groups. Treatments included 5% sodium fluoride (NaF) varnish, casein phosphopeptide-amorphous calcium phosphate (CPP-ACP), Er, Cr: YSGG laser, and diode laser in various combinations. Surface roughness (SR) was measured using a profilometer. S. mutans and S. mitis suspensions were incubated for 24 h, and bacterial adhesion was quantified (×10⁸ Cfu/ml) and visualized using confocal laser scanning microscopy. Tubule occlusion was assessed via SEM imaging and analyzed with ImageJ software. Statistical analysis was performed using one-way ANOVA and Tukey HSD (p = 0.05).</p><p><strong>Results: </strong>Except for the CPP-ACP groups treated with laser, all groups exhibited significantly higher surface roughness (p < 0.05); however, this did not influence bacterial adhesion (p > 0.05). All treatments significantly reduced the number and diameter of open dentinal tubules (p < 0.05). The combination of NaF with Er, Cr: YSGG and diode laser enhanced tubule occlusion, while CPP-ACP with laser had no additional effect.</p><p><strong>Conclusions: </strong>Increased surface roughness, except in CPP-ACP with laser groups, did not affect bacterial adhesion. All desensitization methods effectively promoted tubule occlusion, with the diode laser demonstrating greater efficacy than the Er, Cr: YSGG laser.</p><p><strong>Clinical significance: </strong>Lasers should be used with caution as they may increase the roughness of the dentin surface. The combined application of NaF with lasers may improve its clinical efficacy.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 7","pages":"353"},"PeriodicalIF":3.1,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12198072/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144483417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}