Clinical Oral Investigations最新文献

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DeepPlaq: Dental plaque indexing based on deep neural networks. DeepPlaq:基于深度神经网络的牙菌斑索引。
IF 3.1 2区 医学
Clinical Oral Investigations Pub Date : 2024-09-20 DOI: 10.1007/s00784-024-05921-x
Xu Chen, Yiran Shen, Jin-Sun Jeong, Hiran Perinpanayagam, Kee-Yeon Kum, Yu Gu
{"title":"DeepPlaq: Dental plaque indexing based on deep neural networks.","authors":"Xu Chen, Yiran Shen, Jin-Sun Jeong, Hiran Perinpanayagam, Kee-Yeon Kum, Yu Gu","doi":"10.1007/s00784-024-05921-x","DOIUrl":"https://doi.org/10.1007/s00784-024-05921-x","url":null,"abstract":"<p><strong>Objectives: </strong>The selection of treatment for dental plaque is closely related to the condition of the plaque on different teeth. This study validated the ability of CNN models in assessing the dental plaque indices.</p><p><strong>Materials and methods: </strong>In 70 (20 male and 50 female) healthy adults (18 to 55 years old), frontal and lateral view intraoral images (210) of plaque disclosing agent stained permanent and deciduous dentitions were obtained. A three-stage method was employed, where the You Look Only Once version 8 (YOLOv8) model was first used to detect the target teeth, followed by the prompt-based Segment Anything Model (SAM) segmentation algorithm to segment teeth. A new single-tooth dataset consisting of 1400 photographs was obtained after applying a two-stage method. Finally, a multi-class classification model DeepPlaq was trained and evaluated on the accuracy of dental plaque indexing based on the Quigley-Hein Index (QHI) scoring system. Classification performance was measured using accuracy, recall, precision, and F1-score.</p><p><strong>Results: </strong>The teeth detector exhibited an accuracy (mean average precision, mAP) of approximately 0.941 ± 0.005 in identifying teeth with plaque disclosing agents. The maximum accuracy attained in the plaque indexing through DeepPlaq was 0.84 (probability that DeepPlaq scored identical to experts), and the smallest average scoring error was less than 0.25 on a 0 to 5 scale for scoring.</p><p><strong>Conclusions: </strong>A three-stage approach demonstrated excellent performance in detecting and segmenting target teeth, and DeepPlaq model also showed strong performance in assessing dental plaque indices.</p><p><strong>Clinical relevance: </strong>Application of artificial intelligence to the evaluation of dental plaque distribution could enhance diagnostic accuracy and treatment efficiency and accuracy.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142281445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical and radiographic assessment of gummy smile patients with altered passive eruption: a cross-sectional study in a Thai population 牙龈笑患者被动萌出改变的临床和放射学评估:一项针对泰国人群的横断面研究
IF 3.4 2区 医学
Clinical Oral Investigations Pub Date : 2024-09-19 DOI: 10.1007/s00784-024-05919-5
Thanasak Rakmanee, Yaninee Phromngam, Roumporn Thipraksa, Kitichai Janaphan
{"title":"Clinical and radiographic assessment of gummy smile patients with altered passive eruption: a cross-sectional study in a Thai population","authors":"Thanasak Rakmanee, Yaninee Phromngam, Roumporn Thipraksa, Kitichai Janaphan","doi":"10.1007/s00784-024-05919-5","DOIUrl":"https://doi.org/10.1007/s00784-024-05919-5","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Objectives</h3><p>The study aimed to evaluate the clinical crown length (CCL) among patients diagnosed with altered passive eruption (APE), the causes of a gummy smile, the prevalence of APE, and the correlation between parameters.</p><h3 data-test=\"abstract-sub-heading\">Materials and methods</h3><p>A total of 86 gummy smile patients (516 teeth) underwent clinical examination and assessment using cone-beam computed tomography (CBCT), photography, and intraoral scanning.</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>Significantly shorter CCL and distance between the cementoenamel junction and bone crest (CEJ-BC) were observed among APE-affected teeth (<i>p</i> &lt; 0.05). Among the patients, 56.1% of patients were diagnosed with APE, and most of them were affected by a combination of APE and hypermobile upper lip (HUL). Based on 183 APE-affected teeth, the prevalence of APE types and subtypes was as follows: APE1A (96; 19.3%), APE1B (78; 15.9%), APE2A (8; 1.6%), and APE2B (1; 0.2%). Positive correlations were found between keratinized gingival width (KGW) and bone thickness (BT), while negative correlations were observed between gingival thickness (GT) and BT.</p><h3 data-test=\"abstract-sub-heading\">Conclusion</h3><p>Shorter CCL and CEJ-BC were the highlighted features of APE. APE affected approximately half of the gummy smile patients, with most of them presenting with a combination of HUL. Almost teeth affected by APE were classified as Type I, with a nearly equal distribution between subtypes A and B.</p><h3 data-test=\"abstract-sub-heading\">Clinical relevance</h3><p>The clinical and radiographic features of APE contribute to a better understanding of this condition and facilitate the management of patients affected by APE. Approximately half of gummy smile patients will require multidisciplinary treatment.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142258205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metal artifact reduction tool and mA levels impact on the diagnosis of fracture extension in endodontically treated teeth using cone-beam CT 金属伪影减少工具和 mA 水平对使用锥束 CT 诊断牙髓治疗牙齿折断扩展的影响
IF 3.4 2区 医学
Clinical Oral Investigations Pub Date : 2024-09-19 DOI: 10.1007/s00784-024-05945-3
Luísa Valente Gotardo Lara Alves, Cassiano Ricardo Ferreira Pires, Manoel Damião Sousa-Neto, Heitor Silva Prado, Jardel Francisco Mazzi-Chaves, Amanda Pelegrin Candemil
{"title":"Metal artifact reduction tool and mA levels impact on the diagnosis of fracture extension in endodontically treated teeth using cone-beam CT","authors":"Luísa Valente Gotardo Lara Alves, Cassiano Ricardo Ferreira Pires, Manoel Damião Sousa-Neto, Heitor Silva Prado, Jardel Francisco Mazzi-Chaves, Amanda Pelegrin Candemil","doi":"10.1007/s00784-024-05945-3","DOIUrl":"https://doi.org/10.1007/s00784-024-05945-3","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Aim</h3><p>To evaluate the influence of different levels of metal artifact reduction (MAR) tool and milliamperage (mA) on the diagnosis of fracture extension in endodontically treated teeth using cone beam CT (CBCT).</p><h3 data-test=\"abstract-sub-heading\">Materials and methods</h3><p>Ten maxillary premolars were endodontically treated and positioned in the empty sockets of a human maxilla covered with wax. CBCT acquisitions were performed using the Eagle Edge device (Dabi Atlante, Brazil) adjusted to 120 kVp, FOV of 4 × 6 cm, exposure time of 24 s and voxel size of 0.2 mm in 8 different conditions with different MAR (1, 2 and 3) and mA (3.2 and 6.3) levels. Crown-root fractures were simulated in the universal testing machine, and CBCT images were acquired again. Five radiologists evaluated the presence and extension of fractures with a 5-point scale. Statistical analysis was performed by analysis of variance, Tukey and Kappa test (α = 0.05).</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>Although different mA levels did not significantly (<i>p</i> &gt; 0.05) affect the diagnosis values for fracture presence and extension, when evaluated the different levels of MAR, AUC and sensitivity showed significantly higher values (<i>p</i> &lt; 0.05) for MAR 0 using 6.3 mA and kappa agreement showed significantly higher values (<i>p</i> &lt; 0.05) for MAR 0 and 2 using 6.3 mA.</p><h3 data-test=\"abstract-sub-heading\">Conclusions</h3><p>Although mA levels do not have a diagnostic effect when isolating the MAR level; in 6.3 mA, MAR 0 and 2 can positively influence the diagnosis of fracture extension in endodontically treated teeth using CBCT.</p><h3 data-test=\"abstract-sub-heading\">Clinical relevance</h3><p>The isolate evaluation of dental fracture presence can overlook diagnostics error of its extension.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142258204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of different beverages on the color stability and fluorescence of resin composites: in situ study 不同饮料对树脂复合材料颜色稳定性和荧光的影响:现场研究
IF 3.4 2区 医学
Clinical Oral Investigations Pub Date : 2024-09-19 DOI: 10.1007/s00784-024-05912-y
Lara Pepita de Souza Oliveira, Jardel dos Santos Silva, Luciana da Mata e Silva, Cristiane Maria Brasil Leal, Diego Ferreira Regalado, Carina Toda, Danielson Guedes Pontes
{"title":"Effects of different beverages on the color stability and fluorescence of resin composites: in situ study","authors":"Lara Pepita de Souza Oliveira, Jardel dos Santos Silva, Luciana da Mata e Silva, Cristiane Maria Brasil Leal, Diego Ferreira Regalado, Carina Toda, Danielson Guedes Pontes","doi":"10.1007/s00784-024-05912-y","DOIUrl":"https://doi.org/10.1007/s00784-024-05912-y","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Objective</h3><p>To evaluate the color change (ΔE) and fluorescence (FL) of resin composites after the consumption of beverages.</p><h3 data-test=\"abstract-sub-heading\">Materials and methods</h3><p>One hundred and sixty disc-shaped specimens (6 × 2 mm) of Filtek Z350 XT (FZX) and Forma (FOR) resin composites were randomized for use in devices by five volunteers who ingested 100 ml daily of red wine (RW), beer (BE), energy drink (ED) and water (WT) over 15 days. The data were collected from digital photographs and analyzed using the CIE-Lab and RGB scales to obtain ΔE and FL and statistics via two-way ANOVA (for ΔE) and ANOVA for repeated measures (for FL), α = 0.05.</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>The highest ΔE values were obtained for FZX and FOR in the RW (ΔE = 10.5 for FZX and ΔE = 9.90 for FOR) and BE (ΔE = 6.3 for FZX and ΔE = 6.1 for FOR) drinks. For FL, there were different levels of change between the composites, with a much more significant reduction in FL intensity with RW.</p><h3 data-test=\"abstract-sub-heading\">Conclusion</h3><p>Beverages have the potential to stain the composites evaluated, especially alcoholic beverages.</p><h3 data-test=\"abstract-sub-heading\">Clinical significance</h3><p>Before carrying out an esthetic treatment with resin composites, it is ideal to investigate the types of drinks consumed by patients, for greater predictability of treatment.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142258206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Simultaneous labial and lingual augmented corticotomy assisted presurgical orthodontics in class III patients: the morphological aspects of the mandibular anterior ridge with cone-beam computed tomography 同时对 III 类患者进行唇舌增强皮质切开术辅助术前正畸:锥束计算机断层扫描显示的下颌前嵴形态
IF 3.4 2区 医学
Clinical Oral Investigations Pub Date : 2024-09-17 DOI: 10.1007/s00784-024-05805-0
Jian Liu, Yi Li, Yu Fu, Xiaotong Li, Xiao Xu, Li Xu, Jianxia Hou
{"title":"Simultaneous labial and lingual augmented corticotomy assisted presurgical orthodontics in class III patients: the morphological aspects of the mandibular anterior ridge with cone-beam computed tomography","authors":"Jian Liu, Yi Li, Yu Fu, Xiaotong Li, Xiao Xu, Li Xu, Jianxia Hou","doi":"10.1007/s00784-024-05805-0","DOIUrl":"https://doi.org/10.1007/s00784-024-05805-0","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Objectives</h3><p>This study aims to investigate the changes in alveolar bone following the simultaneous performance of labial and lingual augmented corticotomy (LLAC) in patients with insufficient alveolar bone thickness on both the labial and lingual sides of the mandibular anterior teeth during presurgical orthodontic treatment.</p><h3 data-test=\"abstract-sub-heading\">Materials and methods</h3><p>Thirth-five surgical patients with skeletal Class III malocclusion were included: 19 (LLAC group) accepted LLAC surgery during presurgical orthodontic treatment, and 16 (non-surgery group, NS) accepted traditional presurgical orthodontic treatment. Cone-beam computed tomography (CBCT) scans were obtained before treatment (T0) and at the completion of presurgical orthodontic treatment (T1). The amount of vertical alveolar bone and contour area of the alveolar bone in the labial and lingual sides of mandibular incisors were measured.</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>After presurgical orthodontic treatment, the contour area of the alveolar bone at each level on the lingual side and alveolar bone level on both sides decreased significantly in the NS group (<i>P</i> &lt; 0.001). However, the labial and lingual bone contour area at each level and bone level increased significantly in the LLAC group (<i>P</i> &lt; 0.001). The bone formation rate in the lingual apical region was the highest, significantly different from other sites (<i>P</i> &lt; 0.001).</p><h3 data-test=\"abstract-sub-heading\">Conclusions</h3><p>During presurgical orthodontic treatment, LLAC can significantly increase the contour area of the labio-lingual alveolar bone in the mandibular anterior teeth to facilitate safe and effective orthodontic decompensation in skeletal Class III patients.</p><h3 data-test=\"abstract-sub-heading\">Clinical relevance</h3><p>: This surgery has positive clinical significance in patients lacking bone thickness (&lt; 0.5 mm) in the labial and lingual sides of the lower incisors.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142258207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mandibular overdentures retained by 1 or 2 implants: a 5-year randomized clinical trial on implant stability and peri-implant outcomes 下颌覆盖义齿由 1 个或 2 个种植体固位:关于种植体稳定性和种植体周围效果的 5 年随机临床试验
IF 3.4 2区 医学
Clinical Oral Investigations Pub Date : 2024-09-16 DOI: 10.1007/s00784-024-05914-w
Cláudio Rodrigues Leles, Gabriela Pereira de Resende, Nilva de Oliveira Martins, Lays Noleto Nascimento, Nadia Lago Costa, Murali Srinivasan, Martin Schimmel
{"title":"Mandibular overdentures retained by 1 or 2 implants: a 5-year randomized clinical trial on implant stability and peri-implant outcomes","authors":"Cláudio Rodrigues Leles, Gabriela Pereira de Resende, Nilva de Oliveira Martins, Lays Noleto Nascimento, Nadia Lago Costa, Murali Srinivasan, Martin Schimmel","doi":"10.1007/s00784-024-05914-w","DOIUrl":"https://doi.org/10.1007/s00784-024-05914-w","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Aim</h3><p>This is a report of the 5-year results of a two-group parallel randomized clinical trial comparing longitudinal implant stability, and clinical and radiographic peri-implant outcomes of mandibular overdentures retained by one (1-IOD group) or two (2-IOD group) implants.</p><h3 data-test=\"abstract-sub-heading\">Methods</h3><p>All participants received 4.1 mm diameter tissue-level implants (Straumann<sup>®</sup> Standard Plus – SLActive<sup>®</sup>, Institut Straumann AG), installed in the mandible midline (1-IOD; <i>n</i> = 23) or the lateral incisor-canine area bilaterally (2-IOD; <i>n</i> = 24), and loaded after 3 weeks. Implant Stability Quotient (ISQ) was measured using a resonance frequency device (Osstell<sup>®</sup> Mentor, Integration Diagnostics) at implant placement, after three weeks (loading), and at the 6-month, 1-, 3-, and 5-year follow-ups. Marginal bone loss and clinical implant outcomes (plaque, calculus, suppuration and bleeding) were assessed periodically up to 5 years after loading.</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>Only minor changes in marginal bone level were observed after 5 years (mean = 0.37; SD = 0.44 mm), and satisfactory and stable peri-implant parameters were observed throughout the 5-year follow-up. No significant differences between groups were found. Overall, the mean primary implant stability was considered high (&gt; 70) for the two groups (1-IOD = 78.1 ± 4.5; 2-IOD = 78.0 ± 5.8). No noticeable changes were observed between implant insertion and loading. A marked increase was observed from insertion to the 6-month follow-up – the mean difference for the 1-IOD group was + 5.5 ± 5.5 (Effect size = 1.00), while for the 2-IOD group, the mean difference was + 6.0 ± 5.6 (Effect size = 1.08). No relevant changes were observed throughout the follow-up periods up to 5 years. Linear mixed-effect model regression showed no influence of the bone-related variables (<i>p</i> &gt; 0.05) and the number of implants (<i>p</i> = 0.087), and a significant effect of the time variable (<i>p</i> &lt; 0.001).</p><h3 data-test=\"abstract-sub-heading\">Conclusion</h3><p>Satisfactory peri-implant outcomes and stable secondary stability suggest good clinical performance and successful long-term osseointegration of the implants for single and two-implant mandibular overdentures. Using a single implant to retain a mandibular overdenture does not seem to result in detrimental implant loading over the five years of overdenture use.</p><h3 data-test=\"abstract-sub-heading\">Clinical relevance</h3><p>This study corroborates the use of a single implant to retain a mandibular denture.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142258208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical outcomes and supragingival microbiota analysis around dental implants and teeth in patients with a history of periodontitis: a preliminary study of 6 months follow-up 牙周炎病史患者牙种植体和牙齿周围的临床疗效和龈上微生物群分析:一项为期 6 个月随访的初步研究
IF 3.4 2区 医学
Clinical Oral Investigations Pub Date : 2024-09-16 DOI: 10.1007/s00784-024-05922-w
Nicholas Choo Wee Sim, Anis Rageh Al-Maleki, Eshamsul Sulaiman, Norul Husna Mohamad-Hassan, Syarida Hasnur Safii
{"title":"Clinical outcomes and supragingival microbiota analysis around dental implants and teeth in patients with a history of periodontitis: a preliminary study of 6 months follow-up","authors":"Nicholas Choo Wee Sim, Anis Rageh Al-Maleki, Eshamsul Sulaiman, Norul Husna Mohamad-Hassan, Syarida Hasnur Safii","doi":"10.1007/s00784-024-05922-w","DOIUrl":"https://doi.org/10.1007/s00784-024-05922-w","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Objectives</h3><p>To investigate the supragingival microbiome surrounding dental implants and neighbouring tooth in periodontitis history and periodontally healthy patients.</p><h3 data-test=\"abstract-sub-heading\">Methods</h3><p>Subjects with a history of periodontitis (test) and periodontally healthy subjects (control) received one of two types of dental implants with different surface characteristics: sandblasted acid-etched (SLA) or precision dimension laser-treated (PDL). Periodontal clinical measurements were collected at baseline (V<sub>1</sub>), 3 months after implant placement (V<sub>4</sub>), at zirconia crown placement (V<sub>6</sub>) and 3 months after zirconia crown placement (V<sub>8</sub>). Supragingival bacterial microbiota was studied using Illumina MiSeq sequencing.</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>Supragingival microbial community on SLA implants in test group significantly differed to control group at V<sub>8</sub> (<i>p</i> &lt; 0.05). A longitudinal shift displaying microbial dysbiosis occurred on SLA implants (<i>p</i> &lt; 0.05) and adjacent teeth (<i>p</i> &lt; 0.05) among test patients from V<sub>6</sub> to V<sub>8</sub>. On PDL implants and the adjacent tooth, no significant difference between test and control groups from V<sub>6</sub> to V<sub>8</sub> (<i>p</i> &gt; 0.05). Co-occurrence network in test group of SLA implants and the adjacent tooth at V<sub>8</sub> showed increased disease-associated bacteria and reduced health-associated bacteria. Health-associated bacteria were dominant in control group of SLA implants at V<sub>8</sub>.</p><h3 data-test=\"abstract-sub-heading\">Conclusion</h3><p>The surface characteristics and prosthetic components of dental implants may be important risk factors in patients with a history of periodontitis.</p><h3 data-test=\"abstract-sub-heading\">Clinical relevance</h3><p>Dysbiosis of supragingival microbiome may predispose dental implants to peri-implant diseases. Thus, a strict supportive periodontal care plan is imperative to prevent early onset of biological complications.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142258209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Occlusal disharmony promotes anxiety-like behaviours by suppressing Sirt1 咬合不协调通过抑制 Sirt1 促进焦虑行为
IF 3.4 2区 医学
Clinical Oral Investigations Pub Date : 2024-09-14 DOI: 10.1007/s00784-024-05918-6
Ling Wu, Sihui Zhang, Mi Zhang, Yanjing Ou, Jiang Chen
{"title":"Occlusal disharmony promotes anxiety-like behaviours by suppressing Sirt1","authors":"Ling Wu, Sihui Zhang, Mi Zhang, Yanjing Ou, Jiang Chen","doi":"10.1007/s00784-024-05918-6","DOIUrl":"https://doi.org/10.1007/s00784-024-05918-6","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Background</h3><p>Previous studies have indicated that occlusal disharmony (OD) can promote anxiety-like behaviours. However, the specific molecules involved in the development of anxiety-like behaviours and their underlying mechanisms remain unknown.</p><h3 data-test=\"abstract-sub-heading\">Methods</h3><p>OD was produced by anterior crossbite of female mice. We measured the anxiety levels of mice in each group and screened the hippocampal mRNA expression profiles of mice in the control group and OD group. The role of target mRNA in OD-induced anxiety-like behaviours was evaluated and we preliminarily explored the possible downstream pathways.</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>The results suggested that OD can induce and promote anxiety-like behaviours with/without chronic unpredictable mild stress. We found that Sirt1 was significantly downregulated within the hippocampus in OD mice. In addition, the downregulation of Sirt1 within the hippocampus in OD and control mice promoted anxiety-like behaviours, increased acetylated histone H3 expression and decreased Dnah12 transcription levels. In contrast, in OD mice subjected to an injection of resveratrol, there was a remission of anxiety-like behaviours and an upregulation of Sirt1 in the hippocampus, the effects of which were accompanied by decreased acetylated histone H3 expression and increased Dnah12 transcription levels.</p><h3 data-test=\"abstract-sub-heading\">Conclusions</h3><p>OD leads to increased sensitivity to chronic stress in mice, resulting in anxiety-like behaviours. During this process, Sirt1 acts as an effective factor in the regulation of OD-induced anxiety-like behaviours.</p><h3 data-test=\"abstract-sub-heading\">Clinical relevance</h3><p>OD, as a stressor, could induce anxiety-like behaviours. It investigates the impact of OD (a stressor) on the molecular genetic of the pathophysiology of major neuropsychiatric disorders.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142258211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cleansing efficacy of an oral irrigator with microburst technology in adolescent orthodontic patients. A randomized-controlled crossover study 采用微爆破技术的口腔冲洗器对青少年正畸患者的清洁效果。随机对照交叉研究
IF 3.4 2区 医学
Clinical Oral Investigations Pub Date : 2024-09-13 DOI: 10.1007/s00784-024-05842-9
Hanna Gänzer, Manuel Kasslatter, Vera Wiesmüller, Lena Denk, Anna-Maria Sigwart, Adriano Crismani
{"title":"Cleansing efficacy of an oral irrigator with microburst technology in adolescent orthodontic patients. A randomized-controlled crossover study","authors":"Hanna Gänzer, Manuel Kasslatter, Vera Wiesmüller, Lena Denk, Anna-Maria Sigwart, Adriano Crismani","doi":"10.1007/s00784-024-05842-9","DOIUrl":"https://doi.org/10.1007/s00784-024-05842-9","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Objectives</h3><p>Simplifying interdental space cleaning is a constantly discussed topic. The present study aimed to compare the cleansing efficacy of an oral irrigator with that of dental flossing in adolescent patients with fixed braces after four weeks of home-use.</p><h3 data-test=\"abstract-sub-heading\">Materials and methods</h3><p>The study design is a randomized, single-blinded cross-over study. Following a twenty-eight-day period of product utilization in a home setting, a comparative analysis was conducted on hygiene indices, the Rustogi Modified Navy Plaque Index (RMNPI) and the Gingival Bleeding Index (GBI), between the test group (oral irrigator) and the control group (dental floss).</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>Seventeen adolescent individuals completed the study. After 28 days of cleaning with the oral irrigator, RMNPI was 58.81% (55.31–66.47) compared to 59.46% (52.68–68.67) with dental floss (<i>p</i> = 0.070). Subgroup analyses did not indicate the superiority of either method. GBI after the test phase with the oral irrigator was 28.93% (23.21–33.97) and insignificantly higher compared to 26.40% (21.01–31.41) achieved with dental floss (<i>p</i> = 0.1585).</p><h3 data-test=\"abstract-sub-heading\">Conclusions</h3><p>Neither of the two products demonstrated statistically significant superiority in terms of cleaning efficacy. Therefore, no recommendation can be made in favor of one over the other. It was found that the high initial hygiene indices for fixed orthodontic appliances could be improved through increased awareness and precise instruction.</p><h3 data-test=\"abstract-sub-heading\">Clinical relevance</h3><p>For adolescent patients who struggle to use interdental brushes an oral irrigator may be suggested as a simple alternative in hard-to-reach areas, such as those around a fixed dental appliance.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142204446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of treatment of transverse maxillary deficiency using rapid palatal expansion on oral health-related quality of life in children: complementary results for a controlled clinical trial 使用快速腭部扩张术治疗上颌骨横向缺损对儿童口腔健康相关生活质量的影响:对照临床试验的补充结果
IF 3.4 2区 医学
Clinical Oral Investigations Pub Date : 2024-09-13 DOI: 10.1007/s00784-024-05902-0
Guido Artemio Marañón-Vásquez, Ana Carolina Dias Viana de Andrade, Lucianne Cople Maia, Rogério Lacerda dos Santos, Orlando Motohiro Tanaka, Luiz Renato Paranhos, Dauro Douglas Oliveira, Matheus Melo Pithon
{"title":"Effect of treatment of transverse maxillary deficiency using rapid palatal expansion on oral health-related quality of life in children: complementary results for a controlled clinical trial","authors":"Guido Artemio Marañón-Vásquez, Ana Carolina Dias Viana de Andrade, Lucianne Cople Maia, Rogério Lacerda dos Santos, Orlando Motohiro Tanaka, Luiz Renato Paranhos, Dauro Douglas Oliveira, Matheus Melo Pithon","doi":"10.1007/s00784-024-05902-0","DOIUrl":"https://doi.org/10.1007/s00784-024-05902-0","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Objective</h3><p>To evaluate the effect of rapid palatal expansion (RPE) using Haas-type expanders on children’s oral health-related quality of life (OHRQOL) and compare said effect with that previously reported for the use of Hyrax-type expanders.</p><h3 data-test=\"abstract-sub-heading\">Materials and methods</h3><p>Forty participants aged 8–10 years with transverse maxillary deficiency were treated using Haas appliances. OHRQOL was measured using the CPQ<sub>8 − 10</sub> before RPE, during RPE (T<sub>1</sub>), at the end of RPE (T<sub>2</sub>), and 1 month after appliance removal (T<sub>3</sub>). Generalized mixed models were fitted to assess the effect of the Haas-type expander compared to previously collected data (a nontreated and a Hyrax-type expander-treated group).</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>RPE with Haas-type appliances had a negative impact on overall OHRQOL at T<sub>1</sub> and T<sub>2</sub> (<i>P</i> = 0.001), and a positive impact at T<sub>3</sub> (<i>P</i> = 0.001). The Haas-type expander had a significantly greater negative impact on OHRQOL than the Hyrax-type appliance during RPE. At T<sub>1</sub>, overall scores using the Haas-type expander were 1.08 times the scores using the Hyrax-type expander (i.e., 8% increase; 95% CI, 1.01–1.17; <i>P</i> = 0.033). Patients using the Haas appliance had 1.24 times the scores of those using Hyrax-type devices for the oral symptoms domain at T<sub>1</sub> (i.e., 24% increase; 95% CI, 1.06–1.46; <i>P</i> = 0.009).</p><h3 data-test=\"abstract-sub-heading\">Conclusions</h3><p>Correction of the transverse maxillary deficiency by RPE using the Haas appliance in children 8–10 years improves OHRQOL. The Haas- and Hyrax-type devices temporarily worsen OHRQOL during treatment, however, the negative impact is less with the Hyrax-type expander than with the Haas-type expander, because it causes fewer negative oral symptoms.</p><h3 data-test=\"abstract-sub-heading\">Clinical relevance</h3><p>From a patient-centered perspective, the use of the Hyrax over the Haas appliance may be suggested as it causes less negative oral symptoms during use.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142204206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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