Soft Matter最新文献_第5页

Development and characterization of a Dextran/CaCl2-based blood-mimicking fluid: a comparative study of rheological and mechanical properties in artificial erythrocyte suspensions†

IF 2.9 3区化学

Soft Matter Pub Date : 2025-03-26 DOI: 10.1039/D4SM01510J

Gesine Hentschel, Katharina Doll-Nikutta, Marc Mueller, Philipp Berg and Birgit Glasmacher

{"title":"Development and characterization of a Dextran/CaCl2-based blood-mimicking fluid: a comparative study of rheological and mechanical properties in artificial erythrocyte suspensions†","authors":"Gesine Hentschel, Katharina Doll-Nikutta, Marc Mueller, Philipp Berg and Birgit Glasmacher","doi":"10.1039/D4SM01510J","DOIUrl":"10.1039/D4SM01510J","url":null,"abstract":"The development of accurate blood-mimicking fluids (BMFs) is essential for in vitro studies of blood contacting medical devices. Experimental data typically relies on single-phase glycerin/water solutions as substitutes to visualize simplified blood flow. These models are accurate only at high shear rates, limiting their applicability at lower shear rates. In this study, we investigated three potential BMFs, each composed of poly(sodium acrylate-co-acrylamide) hydrogel microparticles (beads) as artificial erythrocytes. Microbeads were produced using microfluidic systems (MFS) and were suspended in three plasma-like solutions: 10% and 50% (v/v) glycerol/water solutions and a Dextran40/CaCl2 solution. The BMFs were evaluated for their rheological and mechanical properties, including particle elasticity, sedimentation behavior, and shear flow analysis, to assess their suitability for mimicking blood. Rheometric measurements were performed at room temperature using a plate-plate configuration, measuring viscosity and shear stress for shear rates of 5–500 s−1. Atomic force microscopy (AFM) measurements were conducted to assess their mechanical response. The Dextran40/CaCl2-based BMF was identified as the most promising, demonstrating rheological and mechanical properties that closely align with those of human blood. This research offers a refined approach to developing blood analogs that better simulate the mechanical response and flow characteristics of blood for the validation and development of blood contacting medical devices.","PeriodicalId":103,"journal":{"name":"Soft Matter","volume":" 16","pages":" 3101-3116"},"PeriodicalIF":2.9,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/sm/d4sm01510j?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Single-lipid tracking reveals heterogeneities in the nanoscale dynamics of colloid-supported lipid bilayers†

IF 2.9 3区化学

Soft Matter Pub Date : 2025-03-26 DOI: 10.1039/D4SM01299B

Levena Gascoigne, Roderick P. Tas, Pepijn G. Moerman and Ilja K. Voets

{"title":"Single-lipid tracking reveals heterogeneities in the nanoscale dynamics of colloid-supported lipid bilayers†","authors":"Levena Gascoigne, Roderick P. Tas, Pepijn G. Moerman and Ilja K. Voets","doi":"10.1039/D4SM01299B","DOIUrl":"10.1039/D4SM01299B","url":null,"abstract":"In this work, we utilize single-particle tracking photoactivated localization microscopy (sptPALM) to explore lipid dynamics in colloid-supported lipid bilayers (CSLBs) with liquid-like (DOPC), gel-like (DPPC), and phase-separated (DOPC:DPPC:cholesterol) membranes. Using total internal reflection fluorescence illumination, we tracked photoactivatable fluorescent dyes conjugated to lipids within these membranes. Analysis of tracked lipids revealed that bilayers across all compositions have heterogeneous dynamics, with lipid mobility varying over three orders of magnitude. We leveraged the temperature-dependent phase behavior of DPPC to transform gel-like membranes at room temperature into liquid-like membranes above 41 °C, which resulted in increased diffusivity and a surprising decrease in heterogeneity. Finally, we perform single lipid tracking in fluid-rich phases within gel-phase regions to demonstrate their dynamics with reduced lipid mobility because of soft confinement within phase-separated microdomains. Our findings have implications for colloidal assembly strategies that exploit ligand mobility to create controlled and reproducible colloidal superstructures.","PeriodicalId":103,"journal":{"name":"Soft Matter","volume":" 16","pages":" 3058-3066"},"PeriodicalIF":2.9,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11957375/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhancing spray retention using cloaked droplets to reduce pesticide pollution.

IF 2.9 3区化学

Soft Matter Pub Date : 2025-03-25 DOI: 10.1039/d4sm01496k

Vishnu Jayaprakash, Simon Rufer, Sreedath Panat, Kripa K Varanasi

{"title":"Enhancing spray retention using cloaked droplets to reduce pesticide pollution.","authors":"Vishnu Jayaprakash, Simon Rufer, Sreedath Panat, Kripa K Varanasi","doi":"10.1039/d4sm01496k","DOIUrl":"https://doi.org/10.1039/d4sm01496k","url":null,"abstract":"Enhancing agrochemical spray retention on plant surfaces would have tremendous benefits to global health and the environment. The bouncing of sprayed pesticide droplets from hydrophobic leaves is a major source of water and soil pollution, and the resultant overuse of pesticides is a human health hazard and a financial burden for farmers. Here we report on the development of sustainable agricultural sprays consisting of cloaked droplets that significantly enhance droplet retention on plant surfaces. By leveraging wetting dynamics, we create cloaked droplets that consist of an ultra-thin food and environmentally safe oil layer (<1% by volume) that encapsulates water droplets. We develop a fundamental understanding of the dynamics of cloaked droplet impact and retention on superhydrophobic surfaces. Using high-speed imaging, we capture how the oil cloak transforms into a wetting ridge that pins the droplets and suppresses their rebound. We span a wide range of impact conditions, oils, oil viscosities, and oil volume fractions to demonstrate the robustness of the approach. By considering a balance of kinetic energy, the work of adhesion, and viscous dissipation in this four-phase system, we develop a physical model that allows us to establish a regime map for rebound suppression. Finally, these findings are implemented into a prototype sprayer which leads to a ∼5-fold reduction in spray waste on crop leaves. We believe that our spray approach can greatly reduce agrochemical pollution as well as pesticide and surfactant usage.","PeriodicalId":103,"journal":{"name":"Soft Matter","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143699082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Narrow escape for active camphor particles: facilitated escape and aging†

IF 2.9 3区化学

Soft Matter Pub Date : 2025-03-25 DOI: 10.1039/D4SM01483A

Raúl Salgado-García, Orlando Díaz-Hernández, Andrés Castañeda-Jonapá, Gustavo Morales-Padrón, Alberto Estudillo, Thomas Buhse and José-Manuel Cruz

{"title":"Narrow escape for active camphor particles: facilitated escape and aging†","authors":"Raúl Salgado-García, Orlando Díaz-Hernández, Andrés Castañeda-Jonapá, Gustavo Morales-Padrón, Alberto Estudillo, Thomas Buhse and José-Manuel Cruz","doi":"10.1039/D4SM01483A","DOIUrl":"10.1039/D4SM01483A","url":null,"abstract":"In this work, we experimentally investigate the narrow escape problem using self-propelled camphor-infused discs, which have the possibility to escape from a bounded circular domain through an opening in the boundary. To analyze the statistical properties of the escape problem, we proposed two experimental protocols: first, a control setup within a closed circular domain where the disc encounters a target simulating an opening on the boundary, and a second setup where a real opening is placed on the boundary of the circular domain. These two setups allow us to compare how the statistical properties of escape differ between simulated (or fictitious) escape and the actual escape of camphor particles. Our results suggest that the presence of an actual opening in the wall alters the interactions between the particle and the boundary. Notably, we observe the counterintuitive phenomenon that introducing a real door in the boundary makes less accessible the escape from the domain. We further contrast and analyze several qualitative and quantitative properties of the system, including chiral flips, bouncing behavior, arrival angle distribution, as well as first passage time and exit time distributions, among other dynamical properties.","PeriodicalId":103,"journal":{"name":"Soft Matter","volume":" 16","pages":" 3080-3091"},"PeriodicalIF":2.9,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sampling the large-dimensional energy landscape of a 2D granular system with the hydra string method.

IF 2.9 3区化学

Soft Matter Pub Date : 2025-03-25 DOI: 10.1039/d4sm01337a

Katherine A Newhall

{"title":"Sampling the large-dimensional energy landscape of a 2D granular system with the hydra string method.","authors":"Katherine A Newhall","doi":"10.1039/d4sm01337a","DOIUrl":"https://doi.org/10.1039/d4sm01337a","url":null,"abstract":"In this work, I improve upon the existing hydra string method [C. Moakler and K. A. Newhall, Granular Matter, 2021, 24, 24] to systematically sample the energy landscape of a low friction 2D granular system. This method climbs in random directions out of a minimum energy state, finding unique saddle transition points and the neighboring minimum energy states only to repeat the process from the newly found minima. The data is saved as a network with nodes representing the energy-minimizing states and edges representing transition pathways that are parallel to the gradient of the energy at each point along the path. I show how the hydra string method is able to produce a better sample of transition pathways between stable states compared to just randomly sampling the system. The method is also modified to take into account energy minima that are not points caused by non-mechanically stable individual particles and skip past entire configurations that are not mechanically stable. The samples reveal that the energy of the states correlates with the size of the energy barriers between them. Neighboring state energies are also correlated, with correlations decreasing with distance as measured by path length on the network.","PeriodicalId":103,"journal":{"name":"Soft Matter","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143699083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Viscotaxis of beating flagella.

IF 2.9 3区化学

Soft Matter Pub Date : 2025-03-24 DOI: 10.1039/d4sm01328j

Shubham Anand, Jens Elgeti, Gerhard Gompper

{"title":"Viscotaxis of beating flagella.","authors":"Shubham Anand, Jens Elgeti, Gerhard Gompper","doi":"10.1039/d4sm01328j","DOIUrl":"https://doi.org/10.1039/d4sm01328j","url":null,"abstract":"Many biological microorganisms and artificial microswimmers react to external cues of environmental gradients by changing their swimming directions. We study here the behavior of eukaryotic flagellated microswimmers in linear viscosity gradients. Motivated by the near-surface motion of many microswimmers, we consider flagellar swimming in two spatial dimensions. We employ a model of flagellum consisting of a semi-flexible filament with a travelling wave of spontaneous curvature to study generic aspects of viscotaxis of actively beating flagella. The propulsion of the flagellum in a fluid due to a hydrodynamic friction anisotropy is described by resistive-force theory. Using numerical simulations and analytical theory, we show that beating flagella exhibit positive viscotaxis, reorienting themselves toward higher viscosity areas. We quantify this behavior by characterization of the dependence of the rotational velocity on gradient strength, beat amplitude, swimming speed, and wave length. We also examine the effects of asymmetric flagellar wave forms, which imply circular trajectories in the absence of viscosity gradients; here, large asymmetry leads to trochoid-like trajectories perpendicular to the gradient in the form of drifting circles. Flagellar deformability strongly reduce the beat amplitude and the viscotatic response. The viscotatic response is shown to be captured by a universal function of the sperm number.","PeriodicalId":103,"journal":{"name":"Soft Matter","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143699098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Probing particle dynamics in a fully opaque porous network using X-ray differential dynamic radiography (XDDR)†

IF 2.9 3区化学

Soft Matter Pub Date : 2025-03-24 DOI: 10.1039/D4SM01423E

P. Levitz, L. Michot, N. Malikova, M. Scheel and T. Weitkamp

{"title":"Probing particle dynamics in a fully opaque porous network using X-ray differential dynamic radiography (XDDR)†","authors":"P. Levitz, L. Michot, N. Malikova, M. Scheel and T. Weitkamp","doi":"10.1039/D4SM01423E","DOIUrl":"10.1039/D4SM01423E","url":null,"abstract":"Being able to follow in real-time the motion of particles of various nature, shape and size in porous media clearly represents a major research and societal issue. Currently, the leading technique used for tracing particle dynamics in porous media is based on optical microscopy. However, such methods require working with partially transparent samples, which is not the case of many naturally occurring porous media. The latter can indeed be fully opaque, with soil being the most salient example. We propose an alternative method based on recording the time evolution of X-ray radiographs in pure absorption mode. We show that a specific analysis of such a dataset can provide a quantitative determination of the intermediate scattering function (ISF) of these particles in various opaque porous media. The potential of our approach, named X-ray differential dynamic radiography (XDDR), was first checked by simulating random walk dynamics of light colloids inside a porous SiO2 RCP (random close packing) network saturated with water. Potential perturbation induced by Fresnel diffraction is analyzed. Finally, two experiments are performed on the beamline ANATOMIX at the SOLEIL synchrotron, demonstrating the possibility to probe μm SiO2 particle sedimentation either in bulk water or inside a RCP of poly(methyl methacrylate) (PMMA) spheres. XDDR appears to fill a relevant “niche” between DDM (differential dynamics microscopy) and XPCS (X-ray photon correlation spectroscopy), allowing to cover a time scale from 0.2 μs to several minutes and a range (q-range) from 0.1 μm−1 to 5 μm−1.","PeriodicalId":103,"journal":{"name":"Soft Matter","volume":" 16","pages":" 3067-3079"},"PeriodicalIF":2.9,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

How to estimate the surface coverage of polymer grafted planar substrates and spherical nanoparticles

IF 2.9 3区化学

Soft Matter Pub Date : 2025-03-24 DOI: 10.1039/D5SM00005J

Cheng-Wu Li, Holger Merlitz and Jens-Uwe Sommer

引用次数: 0

Electric field-induced control of protein crystal morphology

IF 2.9 3区化学

Soft Matter Pub Date : 2025-03-24 DOI: 10.1039/D5SM00181A

Debes Ray, Mahnoush Madani, Jan K.G. Dhont, Florian Platten and Kyongok Kang

{"title":"Electric field-induced control of protein crystal morphology","authors":"Debes Ray, Mahnoush Madani, Jan K.G. Dhont, Florian Platten and Kyongok Kang","doi":"10.1039/D5SM00181A","DOIUrl":"10.1039/D5SM00181A","url":null,"abstract":"In a previous study (D. Ray, et al., J. Phys. Chem. Lett., 2024, 15, 8108–8113), we found that an alternating electric field considerably affects the location of the crystallization boundary and the liquid–liquid phase separation line as well as crystallization kinetics in lysozyme solutions containing sodium thiocyanate (NaSCN). The present study extends this work by investigating the influence of the same electric field on the microscopic appearance of lysozyme crystals as they form from a supersaturated solution. We observe a variety of distinct crystal morphologies, which we classify as single- and multi-arm crystals, flower-like crystal structures, whiskers, and sea-urchin crystals. Crystal morphologies exhibit significant variations with changes in protein and salt concentrations, and the electric field strongly alters the morphology-state diagram in the protein-versus-salt concentration plane. This alteration is likely due to the field effect on protein–protein interactions. We believe the effect is mediated by the field-enhanced adsorption of SCN− ions to the surface of lysozyme, ultimately driving the observed changes in crystallization behavior. These findings offer insights into how electric fields can be used to control crystal formation and morphology in protein systems.","PeriodicalId":103,"journal":{"name":"Soft Matter","volume":" 16","pages":" 3012-3021"},"PeriodicalIF":2.9,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/sm/d5sm00181a?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143727258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An elastoplastic model approach for the relaxation dynamics of active glasses

IF 2.9 3区化学

Soft Matter Pub Date : 2025-03-21 DOI: 10.1039/D4SM01394H

Tanmoy Ghosh, Peter Sollich and Saroj Kumar Nandi

{"title":"An elastoplastic model approach for the relaxation dynamics of active glasses","authors":"Tanmoy Ghosh, Peter Sollich and Saroj Kumar Nandi","doi":"10.1039/D4SM01394H","DOIUrl":"10.1039/D4SM01394H","url":null,"abstract":"How activity affects the glassy dynamics is crucial for several biological processes. Furthermore, active glasses offer fascinating phenomenologies, extend the scope of equilibrium glass-forming liquids, and can provide novel insights into the original problem. We introduce a family of novel approaches to investigating the relaxation dynamics of active glasses via an active elastoplastic model (EPM). These approaches describe the relaxation dynamics via local plastic yielding and can provide improved insights as we can study various aspects of the system separately. Activity enters the model via three crucial features: activity-mediated plastic yielding, activated barrier crossing, and persistent rotational dynamics of the yielding direction. We first consider a minimal active EPM that adds the effect of active yielding to a thermal EPM. We show that this active EPM captures the known results of active glasses within a reasonable parameter space. The results also agree well with the analytical results for active glasses when activity is small. The minimal model breaks down at very low temperatures where other effects become important. Looking at the broader model class, we demonstrate that whereas active yielding primarily dominates the relaxation dynamics, the persistence of the yielding direction governs the dynamic heterogeneity in active glasses.","PeriodicalId":103,"journal":{"name":"Soft Matter","volume":" 16","pages":" 3047-3057"},"PeriodicalIF":2.9,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0