Soft Matter最新文献_第4页

A durable antifogging anionic-cationic surfactant complex for endoscopic lens applications. 一种耐用的防雾阴离子-阳离子表面活性剂复合物，用于内窥镜应用。

IF 2.9 3区化学

Soft Matter Pub Date : 2026-10-12 DOI: 10.1039/d6sm00669h

Xiaodan Gong, Shuchun Li, Xiujuan He, Xue Pu, Jingqing Zhang, Lu Zang, Yingcheng Li

{"title":"A durable antifogging anionic-cationic surfactant complex for endoscopic lens applications.","authors":"Xiaodan Gong, Shuchun Li, Xiujuan He, Xue Pu, Jingqing Zhang, Lu Zang, Yingcheng Li","doi":"10.1039/d6sm00669h","DOIUrl":"https://doi.org/10.1039/d6sm00669h","url":null,"abstract":"Fogging of endoscopic lenses significantly impairs intraoperative visual clarity and introduces non-negligible surgical safety risks during minimally invasive surgery. Current antifogging agents fail to balance application convenience with long-lasting efficacy, primarily due to poor interfacial adhesion to glass substrates, the standard substrate material for endoscopic lenses. This study designed a durable anionic-cationic antifogging surfactant complex by optimizing the controllable self-assembly guided by molecular dynamics simulations. The complex was a combination of anionic surfactant alcohol ether sulfate sodium (AEnS) and cationic dodecyltrimethylammonium chloride (DTAC), denoted as ADxx (subscripts indicate the anion-to-cation molar ratio). The equimolar AD55 enabled laterally continuous water films and ultrafast wetting within 0.25 s. Strong electrostatic interactions between anionic and cationic headgroups drive the formation of densely packed, hemispherical aggregates at the solid interface (proposed by MD simulations), which markedly suppresses surfactant diffusion at the interface, extending antifogging durability to 2 h (approximately four times that of current antifogging agents). In vivo laparoscopic experiments confirmed that AD55 completely prevents lens fogging and inhibits electrosurgical smoke adhesion throughout surgery when applied via a simple, single-step wipe-on protocol. AD55 is expected to offer a highly promising, clinically translatable antifogging strategy for endoscopic surgery by simple preparation, ultra-rapid wettability and long-term fog resistance.","PeriodicalId":103,"journal":{"name":"Soft Matter","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149163736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Integrating molecular simulations with experimental characterization using a series alignment algorithm. 利用序列比对算法整合分子模拟与实验表征。

IF 2.9 3区化学

Soft Matter Pub Date : 2026-10-12 DOI: 10.1039/d6sm00888g

Huat Thart Chiang, Kiran Vaddi, Souleymane Diallo

{"title":"Integrating molecular simulations with experimental characterization using a series alignment algorithm.","authors":"Huat Thart Chiang, Kiran Vaddi, Souleymane Diallo","doi":"10.1039/d6sm00888g","DOIUrl":"https://doi.org/10.1039/d6sm00888g","url":null,"abstract":"Quantitative comparison between molecular simulations and experimental characterization is often complicated by systematic differences in accessible timescales and control parameters, such that exact matching in absolute units is not generally expected. We introduce a series alignment framework that enables order-preserving, quantitative matching between simulated and experimental observables without requiring one-to-one correspondence in time or temperature. The method formulates the comparison as a global optimization problem over a pairwise distance matrix and identifies an optimal monotonic mapping using dynamic programming. We demonstrate the approach in two case studies: quasi-elastic neutron scattering (QENS) of hydrated lysozyme aligned with molecular dynamics simulations across a range of temperatures and time-resolved small angle X-ray scattering (SAXS) and dynamic light scattering (DLS) measurements of nanoparticle assembly aligned with coarse-grained simulations. In both cases, the alignment reveals systematic offsets between experimental and simulated conditions while preserving physically meaningful trends. This work establishes series alignment as a general framework for integrating simulations with experimental characterization data.","PeriodicalId":103,"journal":{"name":"Soft Matter","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149165422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of a bioadhesive hydrogel with antioxidant activity for enhanced diabetic wound healing. 具有抗氧化活性的生物胶粘剂水凝胶的研制，促进糖尿病伤口愈合。

IF 2.9 3区化学

Soft Matter Pub Date : 2026-10-12 DOI: 10.1039/d6sm00477f

Xin Qiu, Jieyi Zhao, Yuling Zhao, Xiaoyu Wang, Yang Liu

{"title":"Development of a bioadhesive hydrogel with antioxidant activity for enhanced diabetic wound healing.","authors":"Xin Qiu, Jieyi Zhao, Yuling Zhao, Xiaoyu Wang, Yang Liu","doi":"10.1039/d6sm00477f","DOIUrl":"https://doi.org/10.1039/d6sm00477f","url":null,"abstract":"Diabetic chronic wounds which often lead to amputation remain a significant unresolved challenge in clinical practice, posing serious risks to patient health and survival. Existing clinical treatments such as topical administration, traditional dressings and debridement are often inadequate to address the complex pathological microenvironment (chronic inflammation, oxidative stress, etc.) of diabetic chronic wounds, resulting in long treatment cycles and poor outcomes for patients. To address the key pathological factors that impede wound healing, a functional hydrogel dressing was developed in this study using natural polyphenol tannic acid (TA) and biocompatible polyvinyl alcohol (PVA), and aldehyde phenylboronic acid (FPBA) and cyanophenylboronic acid (CPBA) as small molecule crosslinkers. The polyphenol-based hydrogel exhibited strong tissue adhesion, ensuring stable adherence to the wound site after application, thereby preventing infection and mechanical re-injury. And the G-PT hydrogel loaded with TA markedly reduced reactive oxygen species (ROS) production and effectively inhibited DNA damage. Meanwhile, they reduced the levels of early inflammatory factors IL-1β, IL-6 and TNF-α, promoted the polarization of macrophages toward an anti-inflammatory phenotype. In vitro and in vivo evaluations demonstrated that the hydrogel significantly promoted the healing of both acute skin incisions and chronic diabetic wounds by mitigating oxidative stress and regulating macrophage polarization. These findings highlight the therapeutic potential of this multifunctional hydrogel dressing as a promising strategy for treating diabetic wounds.","PeriodicalId":103,"journal":{"name":"Soft Matter","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149163328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Interfacial behaviour of hairy nanoparticle droplets on atomically smooth to physically patterned rough surfaces. 毛状纳米颗粒液滴在原子光滑到物理图案粗糙表面上的界面行为。

IF 2.9 3区化学

Soft Matter Pub Date : 2026-10-09 DOI: 10.1039/d6sm00569a

Mahesh Dhakad, Deepanshu Bagwan, Amartya Sam, Debdip Bhandary

{"title":"Interfacial behaviour of hairy nanoparticle droplets on atomically smooth to physically patterned rough surfaces.","authors":"Mahesh Dhakad, Deepanshu Bagwan, Amartya Sam, Debdip Bhandary","doi":"10.1039/d6sm00569a","DOIUrl":"https://doi.org/10.1039/d6sm00569a","url":null,"abstract":"Hairy nanoparticles (HNPs), consisting of a nanoparticle core with grafted polymer chains, exhibit complex bulk and interfacial behavior due to the intricate interplay between chain conformations and interactions between them. In this study, molecular dynamics simulations are employed to systematically investigate the influence of interaction strength on the structural, dynamical, and wetting properties of HNPs. In the bulk phase, increasing segment-segment (monomer) interaction strength leads to a non-monotonic structural transition, in which HNPs evolve from extended to compact and then re-expand conformations. This behavior is quantified using radial distribution functions, radius of gyration, second virial coefficient, and excess entropy, highlighting the coupling between structure and thermodynamics. Correspondingly, dynamic properties such as diffusivity and viscosity exhibit non-monotonic trends. At interfaces, the wetting behavior of HNP droplets is examined on both smooth and physically patterned surfaces. Increasing segment-surface interaction strength enhances spreading and reduces the equilibrium contact angle. On rough substrates, a transition from Cassie-Baxter-like to Wenzel-like states is observed, governed by the ability of grafted chains to penetrate and conform to surface features. A dimensionless roughness parameter is further introduced to unify surface effects, revealing a nonlinear correlation with contact angle. These findings provide molecular-level insights into how nanoparticle architecture and surface topology control macroscopic properties, offering guidelines for designing functional soft materials with tunable wetting and rheological behavior.","PeriodicalId":103,"journal":{"name":"Soft Matter","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149134194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of combining ultrasound with pH shifting on adsorbed layer formation by pea proteins. 超声结合pH变化对豌豆蛋白吸附层形成的影响。

IF 2.9 3区化学

Soft Matter Pub Date : 2026-10-09 DOI: 10.1039/d6sm00275g

Catherine P Whitby, Qayyum Shehzad

{"title":"Effect of combining ultrasound with pH shifting on adsorbed layer formation by pea proteins.","authors":"Catherine P Whitby, Qayyum Shehzad","doi":"10.1039/d6sm00275g","DOIUrl":"https://doi.org/10.1039/d6sm00275g","url":null,"abstract":"The focus of this paper is on the impact of approaches used to improve protein solubility on its interfacial activity. A range of approaches are used to disperse vegetable proteins in water to stabilize emulsions. Applying physical fields like sonication while pH shifting is thought to have synergistic effects on the emulsifying activity of plant proteins. But the key structural features of proteins that are altered by modification and affect adsorbed layer formation remain unclear. This study evaluated the effects of combining pH shifting and ultrasonication on the interfacial properties of pea proteins. Droplet profile tensiometry and interfacial rheometry were used to compare the adsorption kinetics and interfacial shear moduli of layers formed by pea proteins before and after modification. The first key result is that adsorption and layer formation by the protein are slower in the modified dispersions. This is due to a decrease in the level of disorder in the secondary structure of the protein. The second key result is that layers formed by the modified protein are less elastic due to a reduction in the number of thiol groups available to form connections between molecules. These findings advance our understanding of how increasing protein dispersion can alter the protein structure and hence its interfacial activity.","PeriodicalId":103,"journal":{"name":"Soft Matter","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149134191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Construction of CO₂-responsive wormlike micelles from an aminoglycoside-based pseudo-pentameric surfactant for on-demand antimicrobial release. 基于氨基糖苷的伪五聚体表面活性剂构建co2响应虫状胶束，用于按需抗菌释放。

IF 2.9 3区化学

Soft Matter Pub Date : 2026-10-09 DOI: 10.1039/d6sm00783j

Huoxin Luan, Chao Chen, Dan Guan, Minghao Zeng, Shanshan Liu, Peiling Xu, Yanhong Peng, Xin Su

{"title":"Construction of CO2-responsive wormlike micelles from an aminoglycoside-based pseudo-pentameric surfactant for on-demand antimicrobial release.","authors":"Huoxin Luan, Chao Chen, Dan Guan, Minghao Zeng, Shanshan Liu, Peiling Xu, Yanhong Peng, Xin Su","doi":"10.1039/d6sm00783j","DOIUrl":"https://doi.org/10.1039/d6sm00783j","url":null,"abstract":"CO2-responsive wormlike micelles are smart viscoelastic fluids with broad potential in oilfield stimulation and related fields. However, CO2-switchable systems constructed via the pseudo-surfactant strategy have so far been based mainly on flexible aliphatic polyamines, and the use of aminoglycoside antibiotics as multi-amine building blocks remains unexplored. Herein, we report the first construction of an aminoglycoside-based CO2-responsive pseudo-pentameric surfactant by simply mixing tobramycin-bearing five primary amine groups, a cyclohexose skeleton, and abundant hydroxyl groups-with stearic acid at a 1 : 5 molar ratio in aqueous solution. The resulting system forms highly viscoelastic wormlike micelles with a maximum zero-shear viscosity of ∼3200 mPa s. The system exhibits a lower overlap concentration (c* ≈ 75-85 mM) than the previously reported SA/cyclen pseudo-tetrameric system (c* ≈ 80-100 mM), which we attribute to the combined structural features of tobramycin-including its cyclohexose skeleton, abundant hydroxyl groups, and five primary amines. Moreover, antibacterial assays demonstrate that the wormlike architecture effectively shields tobramycin's activity, while CO2-triggered disassembly restores its full efficacy against Staphylococcus aureus. This work expands CO2-responsive wormlike micelles to aminoglycoside-based pseudo-surfactants and provides a dual-function smart fluid platform that integrates CO2-switchable viscoelasticity with on-demand antimicrobial release, opening avenues for applications ranging from wound dressings and antimicrobial coatings to oilfield biocides.","PeriodicalId":103,"journal":{"name":"Soft Matter","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149134230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In situ elastomer cutting: molecular insights from mechanophores. 原位弹性体切割：来自机械载体的分子见解。

IF 2.9 3区化学

Soft Matter Pub Date : 2026-10-09 DOI: 10.1039/d6sm00388e

Tyler J Roberts, Shaobo Zhan, Stephen P Beaudoin, Shelby B Hutchens, Chelsea S Davis

引用次数: 0

Polymer-mediated mineralization in hydrogels: design principles, hybrid materials, and network visualization. 水凝胶中聚合物介导的矿化：设计原则、杂化材料和网络可视化。

IF 2.9 3区化学

Soft Matter Pub Date : 2026-10-08 DOI: 10.1039/d6sm00511j

Takayuki Nonoyama, Ryuji Kiyama

{"title":"Polymer-mediated mineralization in hydrogels: design principles, hybrid materials, and network visualization.","authors":"Takayuki Nonoyama, Ryuji Kiyama","doi":"10.1039/d6sm00511j","DOIUrl":"https://doi.org/10.1039/d6sm00511j","url":null,"abstract":"Polymer-mediated mineralization in hydrogels offers a versatile route to inorganic-organic hybrids in which mineral formation is coupled to network chemical affinity, precursor transport, spatial confinement, and mechanics. This review first distills the biomineralization concepts most relevant to hydrogel design, including classical and nonclassical nucleation, precursor stabilization, and charge-regulated ion binding. We then organize hydrogel-mineral systems around four experimentally useful variables: chemical affinity, precursor transport, spatial confinement, and network reorganization kinetics. Their interplay governs where nucleation occurs, how amorphous precursors transform, and what architecture is produced. We subsequently distinguish these formation-stage processes from load-induced mechanical relaxation and dissipation in the resulting hybrid materials, which contribute to reinforcement, damage tolerance, interfacial bonding, or time-programmed functions. We further discuss mineralization-assisted electron microscopy, which converts selected polymer networks into electron-dense replicas for direct visualization of mesh structure, heterogeneity, defects, and surface chains, together with emerging image-processing routes for quantitative analysis. Finally, we outline opportunities in dynamic mineralization, hierarchical organization, structural digital twins, and data-driven materials design.","PeriodicalId":103,"journal":{"name":"Soft Matter","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149134284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Curvature-driven wall accumulation in chiral active particles. 手性活性粒子中曲率驱动的壁面积聚。

IF 2.9 3区化学

Soft Matter Pub Date : 2026-10-07 DOI: 10.1039/d6sm00619a

Alessandro Petrini, Raphaël Maire, Umberto Marini Bettolo Marconi, Lorenzo Caprini

引用次数: 0

DeftPunk: an open-source program for detecting topological defects and measuring nematic splay-bend anisotropy. DeftPunk：一个用于检测拓扑缺陷和测量向列斜向弯曲各向异性的开源程序。

IF 2.9 3区化学

Soft Matter Pub Date : 2026-10-07 DOI: 10.1039/d6sm00258g

Quentin Chaboche, Isabelle Bonnet, Carles Blanch-Mercader

{"title":"DeftPunk: an open-source program for detecting topological defects and measuring nematic splay-bend anisotropy.","authors":"Quentin Chaboche, Isabelle Bonnet, Carles Blanch-Mercader","doi":"10.1039/d6sm00258g","DOIUrl":"10.1039/d6sm00258g","url":null,"abstract":"Here, we present an open Python-based program with a graphical interface to characterise topological defects from two-dimensional time-lapses. This program computes the nematic orientation field, identifies defect positions, topological charges, and defect orientations, and estimates the splay-bend anisotropy parameter. The workflow is controlled by three detection parameters adjustable through the interface: the feature size, the order threshold and the phase contour radius. Validation on synthetic datasets with known ground truth yields less than 0.2% false positives and negatives and positional errors comparable to the resolution scale, and the absolute error of the splay-bend anisotropy is 0.03. In addition, we explain a correlation between the detected and input splay-bend anisotropy and provide a calibration curve. Next, we demonstrate applicability across biological systems spanning multiple scales. DeftPunk provides a versatile tool to characterise topological defects and infer elastic anisotropies from microscopy images, opening the way to systematic and quantitative investigations of active nematic dynamics in living systems.","PeriodicalId":103,"journal":{"name":"Soft Matter","volume":" ","pages":"6439-6454"},"PeriodicalIF":2.9,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149011735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0