Soft Matter最新文献_第3页

Computational self-assembly of a six-fold chiral quasicrystal.

IF 2.9 3区化学

Soft Matter Pub Date : 2024-12-09 DOI: 10.1039/d4sm00933a

Nydia Roxana Varela-Rosales, Michael Engel

引用次数: 0

Nanoparticle adhesion at liquid interfaces.

IF 2.9 3区化学

Soft Matter Pub Date : 2024-12-09 DOI: 10.1039/d4sm01101e

Ke Sun, Yonas Gizaw, Halim Kusumaatmaja, Kislon Voïtchovsky

{"title":"Nanoparticle adhesion at liquid interfaces.","authors":"Ke Sun, Yonas Gizaw, Halim Kusumaatmaja, Kislon Voïtchovsky","doi":"10.1039/d4sm01101e","DOIUrl":"https://doi.org/10.1039/d4sm01101e","url":null,"abstract":"Nanoparticle adhesion at liquid interfaces plays an important role in drug delivery, dust removal, the adsorption of aerosols, and controlled self-assembly. However, quantitative measurements of capillary interactions at the nanoscale are challenging, with most existing results at the micrometre to millimetre scale. Here, we combine atomic force microscopy (AFM) and computational simulations to investigate the adhesion and removal of nanoparticles from liquid interfaces as a function of the particles' geometry and wettability. Experimentally, AFM tips with controlled conical geometries are used to mimic the nano-asperities on natural nanoparticles interacting with silicone oil, a model liquid for many engineering applications including liquid-infused surfaces. Computationally, continuum modelling with the Surface Evolver software allows us to visualise the interface configuration and predict the expected force profile from energy minimisation. Quantitative agreement between the experimental measurements and the computational simulations validates the use of continuum thermodynamics concepts down to the nanoscale. We demonstrate that the adhesion of the nanoparticles is primarily controlled by surface tension, with minimum line tension contribution. The particle geometry is the main factor affecting the length of the capillary bridge before rupture. Both the particle geometry and liquid contact angle determine the shape of the adhesion force profile upon removal of the particle from the interface. We further extend our simulations to explore more complex geometries, rationalising the results from experiments with imperfect AFM tips. Our results could help towards the design of smart interfaces, for example, able to attract or repel specific particles based on their shape and chemistry.","PeriodicalId":103,"journal":{"name":"Soft Matter","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142798808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of droplet deposition on aerosol capture efficiency of bipolarly charged fibers.

IF 2.9 3区化学

Soft Matter Pub Date : 2024-12-06 DOI: 10.1039/d4sm01105h

Amit Kumar, Sashank Gautam, Nishant Bhatta, Hooman V Tafreshi, Behnam Pourdeyhimi

{"title":"Effects of droplet deposition on aerosol capture efficiency of bipolarly charged fibers.","authors":"Amit Kumar, Sashank Gautam, Nishant Bhatta, Hooman V Tafreshi, Behnam Pourdeyhimi","doi":"10.1039/d4sm01105h","DOIUrl":"https://doi.org/10.1039/d4sm01105h","url":null,"abstract":"Aerosol filters composed of electrostatically charged bipolar fibers are referred to as electret filters. A novel computational model is developed in this work to study the impact of droplet deposition on aerosol capture efficiency of electret fibers. The electret fibers were assumed to have a dipole orientation that was either parallel or perpendicular to the airflow direction. The simulations were conducted using the ANSYS CFD code after it was enhanced with a series of in-house subroutines. Our simulations revealed that droplet deposition on electret fibers decreases their ability to capture airborne particles. More specifically, the simulations were devised to isolate droplet's physical and electrical properties (e.g., surface tension, electrical conductivity…) and quantify their impact on fiber capture efficiency. It was found, in particular, that droplet's electrical conductivity and permittivity have the most adverse impact on the performance of an electret fiber. This is perhaps because higher droplet conductivity results in severe fiber charge neutralization, and higher droplet permittivity leads to a stronger fiber charge shielding. In contrast, fiber wettability was found to have a negligible impact on fiber efficiency. The work presented in this paper offers valuable insights into the complex nature of electret filters used in different industrial and environmental applications.","PeriodicalId":103,"journal":{"name":"Soft Matter","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142783418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of tough and stiff elastomers by leveraging hydrophilic-hydrophobic supramolecular segment interaction.

IF 2.9 3区化学

Soft Matter Pub Date : 2024-12-06 DOI: 10.1039/d4sm01182a

Jihua Yang, Wei Zhang, Rui Pan, Yizhi Zhuo, Hua Cheng, Awang Zhang, Mengru Liu, Zeqing Wang, Yi Gong, Rui Hu, Jianjun Ding, Lin Chen, Xian Zhang, Xingyou Tian

{"title":"Development of tough and stiff elastomers by leveraging hydrophilic-hydrophobic supramolecular segment interaction.","authors":"Jihua Yang, Wei Zhang, Rui Pan, Yizhi Zhuo, Hua Cheng, Awang Zhang, Mengru Liu, Zeqing Wang, Yi Gong, Rui Hu, Jianjun Ding, Lin Chen, Xian Zhang, Xingyou Tian","doi":"10.1039/d4sm01182a","DOIUrl":"https://doi.org/10.1039/d4sm01182a","url":null,"abstract":"The presence of supramolecular interactions plays a crucial role in the formation of resilient multifunctional elastomers. Nevertheless, achieving elastomers with fabulous mechanical properties remains a significant challenge due to the incomplete understanding of the underlying principles. In this study, we have presented a simple yet efficient approach for manipulating the microstructure, resulting in a significant enhancement of the mechanical properties of the elastomers. By utilizing hydrophobic and hydrophilic extended chain segments to elongate a hydrophilic oligomer, we successfully created elastomers with improved toughness and stiffness through supramolecular interactions. The elastomer with hydrophobic extended chain segments demonstrates a fracture energy (94 842 J m-2) and high tensile stress (16 MPa). In contrast, the elastomer with hydrophilic extended segments showed significantly lower tensile stress (0.18 MPa), even though their molecular chain structures are nearly identical. We conducted a systematic demonstration and investigation of the significant difference mentioned above and ultimately found that due to the hydrophobic-hydrophilic difference between the oligomer and extended chain segments, the hydrophobic chain segments are able to create hydrophobic association and the association can further facilitate the development of stronger and more abundant supramolecular interactions (hydrogen bonds). The resulting hydrogen bonds, combined with the hydrophobic association, effectively disperse energy and consequently improve the elastomer's capacity to withstand external forces. The hydrophilic-hydrophobic mechanism showcases the potential for creating durable supramolecular materials with promising applications in biology and electronics.","PeriodicalId":103,"journal":{"name":"Soft Matter","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142783416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Coacervation for biomedical applications: innovations involving nucleic acids

IF 2.9 3区化学

Soft Matter Pub Date : 2024-12-06 DOI: 10.1039/D4SM01253D

Kimiasadat Mirlohi and Whitney C. Blocher McTigue

{"title":"Coacervation for biomedical applications: innovations involving nucleic acids","authors":"Kimiasadat Mirlohi and Whitney C. Blocher McTigue","doi":"10.1039/D4SM01253D","DOIUrl":"10.1039/D4SM01253D","url":null,"abstract":"Gene therapies, drug delivery systems, vaccines, and many other therapeutics, although seeing breakthroughs over the past few decades, still suffer from poor stability, biocompatibility, and targeting. Coacervation, a liquid–liquid phase separation phenomenon, is a pivotal technique increasingly employed to enhance the effectiveness of therapeutics. Through coacervation strategies, many current challenges in therapeutic formulations can be addressed due to the tunable nature of this technique. However, much remains to be explored to enhance these strategies further and scale them from the benchtop to industrial applications. In this review, we highlight the underlying mechanisms of coacervation, elucidating how factors such as pH, ionic strength, temperature, chirality, and charge patterning influence the formation of coacervates and the encapsulation of active ingredients. We then present a perspective on current strategies harnessing these systems, specifically for nucleic acid-based therapeutics. These include peptide-, protein-, and polymer-based approaches, nanocarriers, and hybrid methods, each offering unique advantages and challenges. Nucleic acid-based therapeutics are crucial for designing rapid responses to diseases, particularly in pandemics. While these exciting systems offer many advantages, they also present limitations and challenges which are explored in this work. Exploring coacervation in the biomedical frontier opens new avenues for innovative nucleic acid-based treatments, marking a significant stride towards advanced therapeutic solutions.","PeriodicalId":103,"journal":{"name":"Soft Matter","volume":" 1","pages":" 8-26"},"PeriodicalIF":2.9,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/sm/d4sm01253d?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142783415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Droplets sliding on soft solids shed elastocapillary rails.

IF 2.9 3区化学

Soft Matter Pub Date : 2024-12-06 DOI: 10.1039/d4sm01041h

Nan Xue, Lawrence A Wilen, Robert W Style, Eric R Dufresne

引用次数: 0

Effect of polyacrylamide gel elasticity on collagen type II fibril assembly†

IF 2.9 3区化学

Soft Matter Pub Date : 2024-12-05 DOI: 10.1039/D4SM01104J

Kathryn G. Wilcox, Stephanie Kramer, Surajit Chatterjee, Adam Linscott, Sneha Suresh, Lydia Kisley and Svetlana Morozova

{"title":"Effect of polyacrylamide gel elasticity on collagen type II fibril assembly†","authors":"Kathryn G. Wilcox, Stephanie Kramer, Surajit Chatterjee, Adam Linscott, Sneha Suresh, Lydia Kisley and Svetlana Morozova","doi":"10.1039/D4SM01104J","DOIUrl":"10.1039/D4SM01104J","url":null,"abstract":"Collagen type II fibrils provide structural integrity to the articular cartilage extracellular matrix. However, the conditions that control the fibril radial size scale, distribution, and formation inside of dense networks are not well understood. We have investigated how surrounding elastic networks affect fibril formation by observing the structure and dynamics of collagen type II in model polyacrylamide gels of varying moduli. Cryogenic transmission electron microscopy (cryo-TEM) is used to image the fibril structure and is verified qualitatively with optical microscopy of fluorescently-tagged collagen within the gels. Using fluorescence correlation spectroscopy super-resolution optical fluctuation imaging (fcsSOFI), the diffusion dynamics of the collagen in low pH and neutral pH conditions are determined. Overall, the fibril bundle diameter and concentration were found to decrease as a function of gel modulus. The single fibril diameter remains constant at 30 nm within the gels; however, the diameter was found to be smaller when compared to in solution. Additionally, the mode of diffusion of the collagen triple helices changes within gel environments, decreasing the diffusion coefficient. Understanding the intricate relationship between network topology and collagen type II fibril formation is crucial in gaining deeper insights into the transport phenomena within complex acellular tissues that are necessary for the development of future therapeutic materials.","PeriodicalId":103,"journal":{"name":"Soft Matter","volume":" 1","pages":" 137-147"},"PeriodicalIF":2.9,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11618509/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142778993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhanced rotational diffusion and spontaneous rotation of an active Janus disk in a complex fluid.

IF 2.9 3区化学

Soft Matter Pub Date : 2024-12-05 DOI: 10.1039/d4sm01142b

Marco De Corato, Paula Martínez-Lera

{"title":"Enhanced rotational diffusion and spontaneous rotation of an active Janus disk in a complex fluid.","authors":"Marco De Corato, Paula Martínez-Lera","doi":"10.1039/d4sm01142b","DOIUrl":"https://doi.org/10.1039/d4sm01142b","url":null,"abstract":"Active colloids and self-propelled particles moving through microstructured fluids can display different behavior compared to what is observed in simple fluids. As they are driven out of equilibrium in complex fluids they can experience enhanced translational and rotational diffusion as well as instabilities. In this work, we study the deterministic and the Brownian rotational dynamics of an active Janus disk propelling at a constant speed through a complex fluid. The interactions between the Janus disk and the complex fluid are modeled using a fluctuating advection-diffusion equation, which we solve using the finite element method. Motivated by experiments, we focus on the case of a complex fluid comprising molecules that are much smaller than the size of the active disk but much bigger than the solvent. Using numerical simulations, we elucidate the interplay between active motion and fluid microstructure that leads to enhanced rotational diffusion and spontaneous rotation observed in experiments employing Janus colloids in polymer solutions. By increasing the propulsion speed of the Janus disk, the simulations predict the onset of a spontaneous rotation and an increase of the rotational diffusion coefficient by orders of magnitude compared to its equilibrium value. These phenomena depend strongly on the number density of the constituents of the complex fluid and their interactions with the two sides of the Janus disk. Given the simplicity of our model, we expect that our findings will apply to a wide range of active systems propelling through complex media.","PeriodicalId":103,"journal":{"name":"Soft Matter","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142783419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhanced diffusion through multivalency.

IF 2.9 3区化学

Soft Matter Pub Date : 2024-12-04 DOI: 10.1039/d4sm00778f

Ladislav Bartoš, Mikael Lund, Robert Vácha

{"title":"Enhanced diffusion through multivalency.","authors":"Ladislav Bartoš, Mikael Lund, Robert Vácha","doi":"10.1039/d4sm00778f","DOIUrl":"10.1039/d4sm00778f","url":null,"abstract":"The diffusion of macromolecules, nanoparticles, viruses, and bacteria is essential for targeting hosts or cellular destinations. While these entities can bind to receptors and ligands on host surfaces, the impact of multiple binding sites-referred to as multivalency-on diffusion along strands or surfaces is poorly understood. Through numerical simulations, we have discovered a significant acceleration in diffusion for particles with increasing valency, while maintaining the same overall affinity to the host surface. This acceleration arises from the redistribution of the binding affinity of the particle across multiple binding ligands. As a result, particles that are immobilized when monovalent can achieve near-unrestricted diffusion upon becoming multivalent. Additionally, we demonstrate that the diffusion of multivalent particles with a rigid ligand distribution can be modulated by patterned host receptors. These findings provide insights into the complex diffusion mechanisms of multivalent particles and biological entities, and offer new strategies for designing advanced nanoparticle systems with tailored diffusion properties, thereby enhancing their effectiveness in applications such as drug delivery and diagnostics.","PeriodicalId":103,"journal":{"name":"Soft Matter","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11615653/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142765007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ultrahigh yields of giant vesicles obtained through mesophase evolution and breakup†

IF 2.9 3区化学

Soft Matter Pub Date : 2024-12-02 DOI: 10.1039/D4SM01109K

Alexis Cooper and Anand Bala Subramaniam

{"title":"Ultrahigh yields of giant vesicles obtained through mesophase evolution and breakup†","authors":"Alexis Cooper and Anand Bala Subramaniam","doi":"10.1039/D4SM01109K","DOIUrl":"10.1039/D4SM01109K","url":null,"abstract":"Self-assembly of dry amphiphilic lipid films on surfaces upon hydration is a crucial step in the formation of cell-like giant unilamellar vesicles (GUVs). GUVs are useful as biophysical models, as soft materials, as chassis for bottom-up synthetic biology, and in biomedical applications. Here via combined quantitative measurements of the molar yield and distributions of sizes and high-resolution imaging of the evolution of thin lipid films on surfaces, we report the discovery of a previously unknown pathway of lipid self-assembly which can lead to ultrahigh yields of GUVs of >50%. This yield is about 60% higher than any GUV yield reported to date. The “shear-induced fragmentation” pathway occurs in membranes containing 3 mol% of the poly(ethylene glycol) modified lipid PEG2000-DSPE (1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]), when a lipid-dense foam-like mesophase forms upon hydration. The membranes in the mesophase fragment and close to form GUVs upon application of fluid shear. Experiments with varying mol% of PEG2000-DSPE and with lipids with partial molecular similarity to PEG2000-DSPE show that ultrahigh yields are only achievable under conditions where the lipid-dense mesophase forms. The increased yield of GUVs compared to mixtures without PEG2000-DSPE was general to flat supporting surfaces such as stainless steel sheets and to various lipid mixtures. In addition to increasing their accessibility as soft materials, these results demonstrate a route to obtaining ultrahigh yields of cell-sized liposomes using longstanding clinically-approved lipid formulations that could be useful for biomedical applications.","PeriodicalId":103,"journal":{"name":"Soft Matter","volume":" 48","pages":" 9547-9561"},"PeriodicalIF":2.9,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/sm/d4sm01109k?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142765040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0