Splay and bend deformations in cells near corners.

IF 2.9 3区 化学 Q3 CHEMISTRY, PHYSICAL
Soft Matter Pub Date : 2025-06-26 DOI:10.1039/d5sm00093a
Aniruddh Murali, Prasoon Awasthi, Kirsten Endresen, Arkadiusz Goszczak, Francesca Serra
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引用次数: 0

Abstract

The study of spindle-like cells as nematic liquid crystals has led to remarkable insights in the understanding of tissue organization and morphogenesis. In the characterization of this anomalous liquid crystal material, we focus on the energetic cost of splay and bend deformations, in order to determine the elastic anisotropy of the material, i.e. the ratio of the elastic constants associated with splay and bend. We explore the behavior of monolayers of cells in proximity to corners, where cells arrange in splay or bend configuration, depending on the amplitude of the wedge angle. The angle at which splay and bend deformations are equally likely is determined by the ratio between splay and bend elastic constants. Our data suggest that for fibroblast cells the common approximation of bend and splay constants being equal is valid.

在角落附近的单元格中展开和弯曲变形。
纺锤状细胞作为向列液晶的研究在组织组织和形态发生的理解上有了显著的见解。在这种异常液晶材料的表征中,我们关注的是弯曲变形的能量成本,以确定材料的弹性各向异性,即与弯曲和弯曲相关的弹性常数的比率。我们探索了靠近角落的单层细胞的行为,其中细胞以摊开或弯曲的形式排列,这取决于楔角的振幅。发生伸展变形和弯曲变形的可能性相等的角度由伸展和弯曲弹性常数之间的比值决定。我们的数据表明,对于成纤维细胞,弯曲常数和张开常数相等的共同近似是有效的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Soft Matter
Soft Matter 工程技术-材料科学:综合
CiteScore
6.00
自引率
5.90%
发文量
891
审稿时长
1.9 months
期刊介绍: Soft Matter is an international journal published by the Royal Society of Chemistry using Engineering-Materials Science: A Synthesis as its research focus. It publishes original research articles, review articles, and synthesis articles related to this field, reporting the latest discoveries in the relevant theoretical, practical, and applied disciplines in a timely manner, and aims to promote the rapid exchange of scientific information in this subject area. The journal is an open access journal. The journal is an open access journal and has not been placed on the alert list in the last three years.
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