Clinical and Experimental Dental Research最新文献

{"title":"Pulp Stone Formation Following Fixed Orthodontic Treatment: A Panoramic Radiographic Comparison of Extraction and Non-Extraction Approaches","authors":"Kosar Gholinezhad,&nbsp;Hakimeh Ghorbani,&nbsp;Seyedali Seyedmajidi,&nbsp;Sedigheh Sheikhzadeh,&nbsp;Manouchehr Rahmati Kamel","doi":"10.1002/cre2.70181","DOIUrl":"https://doi.org/10.1002/cre2.70181","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>The impact of orthodontic forces on pulp stone formation has been the focus of several studies. Given that orthodontic extractions typically involve the application of greater forces to the teeth, the aim of this study was to compare the extent of pulp stone formation in the molar teeth of patients undergoing orthodontic treatment with and without extractions.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>In this retrospective observational study, panoramic radiographs of 80 orthodontic patients taken between 2014 and 2020 (equally divided into extraction and non-extraction groups) who had a full set of permanent molars were analyzed before and after orthodontic treatment to assess the formation of pulp stones in the pulp chambers of the molar teeth (640 molars). Data were analyzed using the Chi-square and McNemar tests with a significance level set at <i>p</i> &lt; 0.05, using SPSS software.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The frequency of pulp stone formation significantly increased in both the extraction and non-extraction groups following fixed orthodontic treatment (<i>p</i> &lt; 0.001 and <i>p</i> = 0.02, respectively). However, no statistically significant difference was observed in the extent of pulp stone formation between the two groups (<i>p</i> = 0.09). The frequency of patients exhibiting pulp stone formation did not differ significantly by gender in either the extraction or non-extraction treatment groups (<i>p</i> = 0.392 and <i>p</i> = 0.451, respectively). In the extraction group, the prevalence of pulp stones was significantly higher in the first molar compared to the second molar (<i>p</i> = 0.001). In contrast, no significant difference was found between the first and second molars in the non-extraction group (<i>p</i> = 0.108). Additionally, no correlation was found between the frequency of pulp stone formation and jaw type (maxilla or mandible) in either group (<i>p</i> &gt; 0.05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Fixed orthodontic treatment is associated with increased pulp stone formation, regardless of whether extractions are performed. These findings may help clinicians in the early identification and monitoring of at-risk teeth.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"11 4","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cre2.70181","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144705482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to “Optimizing Osseodensification Drilling for Dental Implant Placement: An In Vitro Study”","authors":"","doi":"10.1002/cre2.70176","DOIUrl":"https://doi.org/10.1002/cre2.70176","url":null,"abstract":"<p>Tao, X., Yang, J., Ma, T., Chen, M., An, Q., &amp; Yu, D. (2025). Optimizing Osseodensification Drilling for Dental Implant Placement: An In Vitro Study. <i>Clinical and Experimental Dental Research</i> 11(3), e70155. https://doi.org/10.1002/cre2.70155</p><p>In the affiliation section of the published article, the co-corresponding author Dr. Qinglong An was incorrectly listed under:</p><p>“5 Fengcheng Branch, Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China”</p><p>Correction:</p><p>The correct affiliation for Dr. Qinglong An is:“4 State Key Laboratory of Mechanical System and Vibration, School of Mechanical Engineering, Shanghai Jiao Tong University, Shanghai, China”</p><p>We apologize for this error.</p>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"11 4","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cre2.70176","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144705480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predicting the Recurrence of Sporadic Odontogenic Keratocyst Using Whole-Slide Histopathology Images With the Hybrid Encoder Iterative Attention Convolution Model","authors":"Samahit Mohanty,&nbsp;Divya Biligere Shivanna,&nbsp;Roopa S. Rao,&nbsp;Madhusudan Astekar","doi":"10.1002/cre2.70184","DOIUrl":"https://doi.org/10.1002/cre2.70184","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Odontogenic keratocysts (OKCs) are challenging due to their aggressiveness and high recurrence rates, complicating decision-making for clinicians and pathologists. Despite efforts to identify predictive characteristics, management remains challenging. The study aims to design a reliable artificial intelligence model to enhance predictive models and distinguish between recurrent and nonrecurrent whole-slide images of OKCs.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>84 OKC cases were selected for this study, including 29 whole slide images (WSIs) of recurrent OKCs and 35 WSIs of non-recurrent OKCs for model development. The model was evaluated using 14 non-recurrent and 6 recurrent cases. The proposed Hybrid Encoder Iterative Attention Convolution (HEIAC) model integrates the strengths of three fundamental components: an encoder, an attention mechanism, and convolutional layers to classify images effectively. The encoder learns to extract useful features, resulting in more meaningful representations that capture the underlying structure of the image data. Iterative attention enables the model to capture intricate details and subtle patterns that may be crucial for accurate image classification. Convolutional layers are designed to learn hierarchical representations of image features automatically. This model harnesses the capabilities of each component to achieve robust and accurate image classification.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The proposed HEIAC model attained 0.98 testing accuracy and exhibits superior performance across the majority of evaluation metrics, achieving 96% recall, 100% precision, a 97% F1-score, and a perfect AUC of 1.0, and used 96% fewer trainable parameters than the standard vision transformer.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>This approach improves predictive models for distinguishing recurrent and non-recurrent OKCs.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"11 4","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cre2.70184","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144688130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Developmental Defect of Enamel in Permanent Teeth Associated With Chronic Endodontic Abscess in Deciduous Teeth: A Retrospective Study","authors":"Federica Guglielmi,&nbsp;Angela Malatesta,&nbsp;Anna Alessandri-Bonetti,&nbsp;Patrizia Gallenzi","doi":"10.1002/cre2.70185","DOIUrl":"https://doi.org/10.1002/cre2.70185","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Destructive carious lesions on deciduous teeth often result in dental abscesses. Sometimes, the exudative process may extend to the dental follicle of the permanent tooth, leading to various types of consequences. This study primarily seeks to determine the prevalence of developmental defects of enamel (DDE) in premolars whose predecessors developed endodontic abscesses. Furthermore, it investigates how the prevalence of DDE is influenced by the type of treatment the affected deciduous molar received. Lastly, the study compares the prevalence of DDE between maxillary and mandibular premolars.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>Demographics, medical and dental history, and records of DDE were extracted from the medical records of 1164 pediatric patients. DDE of 107 premolars from patients who had experienced abscesses in their deciduous molars were compared to DDE of 107 premolars from patients who naturally shed healthy deciduous molars. DDE were also compared between different treatment modalities and anatomical regions. Fisher's exact tests were used to compare groups, while demographic data were analyzed by descriptive statistics and reported as mean ± standard deviation or as median and interquartile range for the continuous variables.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Compared to premolars whose predecessors did not exhibit signs of pathology, those that developed endodontic abscesses reported a higher prevalence of DDE (57% vs. 17.8%; OR 6.14; <i>p</i> &lt; 0.0001). Endodontic treatment on deciduous molars was associated with higher DDE prevalence compared to surgical treatment (70.2% vs. 46.7%; OR 2.69; <i>p</i> = 0.016). Maxillary premolars showed a higher prevalence of DDE compared to mandibular premolars (75.4% vs. 24.6%; OR 5.23; <i>p</i> = 0.00008).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Chronic endodontic abscess on deciduous molars significantly increases the risk of DDE in the corresponding premolars. ET on deciduous molars is associated with higher incidence of DDE compared to extraction. Maxillary premolars are more likely to develop DDE than mandibular premolars.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"11 4","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cre2.70185","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144688131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Flapless Immediate Implant Placement With and Without Bone Grafting: A Systematic Review and Meta-Analysis","authors":"Saeed Sadat Mansouri,&nbsp;Farhan Musaie,&nbsp;Abbas Mirzaei,&nbsp;Samad Samadizadeh,&nbsp;Salar Chaychi Salmasi,&nbsp;Tahereh Bitaraf","doi":"10.1002/cre2.70182","DOIUrl":"https://doi.org/10.1002/cre2.70182","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>This study aims to evaluate the influence of bone grafting peri-implant gap on the changes in hard and soft tissues following flapless immediate implantation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>A comprehensive research process was undertaken, including electronic searches of databases such as Embase, PubMed, Web of Science, and Cochrane, as well as a manual search. This approach identified relevant clinical studies until March 2024. Randomized controlled trials (RCTs) that compared flapless immediate implant placement with and without bone grafting were selected for qualitative assessment. Meta-analyses were conducted where feasible. The protocol was registered in PROSPERO with code CRD42024499377, ensuring transparency and accountability in our research.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Out of 1065 articles, 5 RCTs were included, involving 179 patients who underwent placement of 179 immediate implants (92 with bone grafting and 87 without) with follow-up periods ranging from 6 to 12 months. Analysis revealed no significant differences in horizontal bone changes within 0 to 3 mm apical to the bone crest between the two groups (weighted mean difference [WMD]: 0.147 (−0.012, 0.306), <i>I</i>²: 0.0%; standardized mean difference [SMD]: 0.337 (−0.016, 0.690), <i>I</i>²: 0.0%). However, significant differences were observed in horizontal bone changes at 4–5 mm apical to the reference point, favoring bone grafting (WMD: 0.484 (0.142, 0.826), <i>I</i>²: 75.4%; SMD: 0.794 (0.402, 1.186), <i>I</i>²: 36.6%). No significant differences were found in vertical midfacial soft tissue changes between the groups (WMD: 0.300 (−0.425, 1.024), <i>I</i>²: 62.4%; SMD: 0.213 (−0.339, 0.764), <i>I</i>²: 60.2%). Data limitations precluded meta-analyses on additional outcomes such as mesial and distal papillary alterations and vertical bone level changes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Flapless immediate dental implants with a bone graft may enhance alveolar bone preservation, warranting further investigation.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"11 4","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cre2.70182","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144688094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Root Canal Cleaning and Irrigant Penetration Using Different Irrigation Protocols: A Combined SEM and Single-Tooth Micro-CT Study","authors":"Alfredo Iandolo,&nbsp;Niccolò Giuseppe Armogida,&nbsp;Davide Mancino,&nbsp;Gianrico Spagnuolo,&nbsp;Mariangela Cernera,&nbsp;Dina Abdellatif","doi":"10.1002/cre2.70175","DOIUrl":"https://doi.org/10.1002/cre2.70175","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>This study evaluated the effectiveness of different irrigation techniques in removing debris and smear layers and in improving irrigant penetration within root canals. Particular attention was given to the 3D Cleaning technique, which combines ultrasonic activation with internal heating of sodium hypochlorite.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>Fifty-one single-rooted human mandibular premolars were used. Group A (<i>n</i> = 50) was divided into five subgroups (<i>n</i> = 10 each), each receiving a different irrigation protocol (control, syringe irrigation, sonic activation, ultrasonic activation, and 3D Cleaning). Scanning electron microscopy (SEM) at ×1000 magnification was used to evaluate debris and smear layer removal based on a validated scoring system. Group B (<i>n</i> = 1) consisted of a single premolar with a lateral canal in the apical third, examined using microcomputed tomography (micro-CT). The same tooth underwent all five irrigation protocols in sequence, with radiopaque irrigant penetration evaluated after each and confirmed through sequential micro-CT scans. A power analysis confirmed the adequacy of sample size (<i>n</i> = 50; α = 0.05, power<i> </i>= 80%). Non-parametric tests were used, including Kruskal–Wallis ANOVA for intergroup comparisons, followed by Mann–Whitney <i>U</i> tests with Bonferroni correction for post hoc pairwise analysis (<i>p</i> &lt; 0.05 considered significant).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The 3D Cleaning technique (ultrasonic activation + internal heating) achieved the lowest debris and smear layer scores and the highest irrigant penetration depth (~0.6 mm) into the lateral canal. The control group showed no penetration and the highest debris scores. Conventional syringe and sonic activation showed moderate cleaning and penetration (0.2–0.3 mm), while ultrasonic activation alone showed slightly better results (~0.4 mm).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The 3D Cleaning technique demonstrated superior effectiveness in root canal cleaning and irrigant penetration compared to conventional irrigation methods. These results support the clinical relevance of heating-activated irrigation protocols to enhance root canal disinfection.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"11 4","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cre2.70175","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144647103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association Between DMFT Index, Dental Plaque, and Pre-eclampsia in Pregnant Women: A Case–Control Study","authors":"Mehdi Shirinzad,&nbsp;Mohammad Moradi Dalir,&nbsp;Azita Tiznobaik,&nbsp;Farideh Kazemi,&nbsp;Zohreh Momenimovahed","doi":"10.1002/cre2.70177","DOIUrl":"https://doi.org/10.1002/cre2.70177","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>This study investigates the association between Decayed, Missing, and Filled Teeth (DMFT) Index, dental plaque (assessed via Plaque Index [PI]), and pre-eclampsia in pregnant women.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>A case–control study was conducted with 70 pregnant women diagnosed with pre-eclampsia (cases) and 70 without (controls), matched for demographic and obstetric variables. Data were collected using a checklist capturing demographic details, obstetric history, and oral health parameters (DMFT and PI). Statistical analyses included chi-square tests, independent <i>t</i>-tests, and multiple logistic regression.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The case group exhibited a significantly higher mean DMFT index (11.70 ± 2.88 vs. 9.21 ± 2.24, <i>p</i> &lt; 0.001) and PI (33.26 ± 9.21 vs. 28.30 ± 7.26, <i>p</i> &lt; 0.001) compared to controls. Each one-unit increase in the DMFT index and PI was associated with 19% and 5% increased odds of pre-eclampsia, respectively (<i>p</i> &lt; 0.001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Dental caries and plaque are significantly associated with pre-eclampsia in pregnant women. Integrating oral health assessments into antenatal care is recommended to mitigate these risks and improve maternal and fetal outcomes.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"11 4","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cre2.70177","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144647102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surface Roughness and Wear Behavior of CAD/CAM Ceramics Against Vita Mark II","authors":"Amirhosein Habibnezhad,&nbsp;Gazaleh Ahmadi,&nbsp;Naeeme Naderi","doi":"10.1002/cre2.70174","DOIUrl":"https://doi.org/10.1002/cre2.70174","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>This study aimed to assess the surface roughness (SR) and wear behavior of computer-aided design/computer-aided manufacturing (CAD/CAM) ceramics when compared to a feldspathic ceramic.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>This in vitro study was conducted on three groups of CAD/CAM ceramic blocks (<i>n</i> = 10 each): a zirconia-reinforced lithium silicate ceramic, a polymer-infiltrated ceramic network, and a resin nanoceramic. Additionally, 40 feldspathic ceramic blocks and 10 bovine incisors were used as antagonist materials. Surface roughness was measured by profilometry before and after wear testing (49 N, 120,000 cycles, 30 cycles/min). Wear depth was quantified using 3D scanning and image analysis software. Data were analyzed using ANOVA and paired <i>t</i>-tests (α = 0.05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Before wear testing, the zirconia-reinforced ceramic showed significantly higher SR than the other groups (<i>p</i> = 0.00). All groups exhibited a significant reduction in SR after testing (<i>p</i> = 0.00). Posttest SR varied significantly between most groups (<i>p</i> &lt; 0.05), except between natural enamel and the resin nanoceramic (<i>p</i> = 0.986). Wear depth differed significantly among the materials (<i>p</i> &lt; 0.001), with natural enamel showing the lowest wear, comparable only to the resin nanoceramic (<i>p</i> &gt; 0.05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>All tested CAD/CAM ceramics underwent substantial wear and SR reduction when opposed by feldspathic ceramic. The resin nanoceramic demonstrated the closest wear behavior to natural enamel and may be the most suitable restorative material for contact with feldspathic ceramics.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"11 4","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cre2.70174","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144615343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Analysis of 3D Imaging in Periodontal Disease Assessment: A Systematic Review and Meta-Analysis","authors":"Ravinder S. Saini,&nbsp;Sunil Kumar Vaddamanu,&nbsp;Masroor Ahmed Kanji,&nbsp;Seyed Ali Mosaddad,&nbsp;Artak Heboyan","doi":"10.1002/cre2.70169","DOIUrl":"https://doi.org/10.1002/cre2.70169","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>The present systematic review and meta-analysis aimed to compare the efficacy of three-dimensional (3D) imaging techniques in terms of accuracy and precision for periodontal disease assessment.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>A literature search was conducted across multiple databases (PubMed, Scopus, Web of Science, Google Scholar, and ScienceDirect) following Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) protocols. The primary outcomes focused on comparing the accuracy and precision of 3D versus two-dimensional (2D) imaging techniques. Furthermore, it assessed their performance in determining periodontal diseases. Quality assessment was performed using the risk of bias (RoB)-2 for randomized controlled trials (RCTs) and ROB in nonrandomized studies-Intervention (ROBINS-I) for non-RCTs. Meta-analysis was conducted using RevMan 5.4 with a significance level set at 0.01. While meta-regression was performed using OpenMEE.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>After screening, 22 studies met the eligibility criteria for qualitative and quantitative analysis. Qualitatively, 3D imaging, particularly cone-beam computed tomography (CBCT), showed superior accuracy and precision over 2D techniques. The meta-analysis revealed significant differences in several areas: overall (<i>p</i> = 0.00001, Mean Difference (MD) = −0.36, 95% confidence interval [CI]: −0.96 to 0.24, <i>I</i>² = 93%), horizontal measurements (<i>p</i> = 0.00001, MD = −0.75, 95% CI: −2 to −0.49, <i>I</i>² = 92%), and vertical measurements (<i>p</i> = 0.00001, MD = −0.59, 95% CI: −2.40 to 1.23, <i>I</i>² = 92%). Nonsignificant differences were found for furcation height, width, and depth. Most studies showed good quality with a low risk of bias. Age of the participants and study quality were found to be the sources of heterogeneity.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Consistent trends highlight the advantages of 3D imaging in assessing both periodontal and nonperiodontal diseases. However, given the nonsignificant differences in furcation height, width, and depth, the recommended approach is to combine CBCT with digital intraoral radiography for more comprehensive periodontal bone assessment.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"11 4","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cre2.70169","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144615201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electrophysiological Study of the Masticatory Muscle Activity in Patients With Temporomandibular Disorders With and Without Tinnitus","authors":"Henri Albert Didier,&nbsp;Alberto Maria Cappellari,&nbsp;Federica Di Berardino,&nbsp;Margherita Donelli,&nbsp;Xi Xi Fan,&nbsp;Laura Magnoni,&nbsp;Giorgio Lilli,&nbsp;Stefania Barozzi,&nbsp;Diego Zanetti,&nbsp;Flavio Arnone,&nbsp;Alexandre Henri Didier,&nbsp;Gennaro Bussone,&nbsp;Alberto Caprioglio,&nbsp;Aldo Bruno Giannì","doi":"10.1002/cre2.70172","DOIUrl":"https://doi.org/10.1002/cre2.70172","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>The relationship between tinnitus and temporomandibular disorders (TMD) over the years has continued to be widely debated in literature and not yet fully understood. Several causes have been associated with tinnitus including altered mandibular posture and disorders at the muscle, joint and periodontal receptors. This study aimed to investigate masseter and temporalis muscle activity in patients with TMD with and without somatosensory tinnitus (ST).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>A total of 105 patients (mean age 50.49 ± 11.7 years) with TMD classified according to Axis I DC/TMD diagnostic criteria were enrolled and then divided into two groups: 53 subjects with ST and 52 without ST. Electromyographic and kinesiographic instrumental examinations were used for data collection. Statistical analyses, including Levene's test and independent <i>t</i>-test, were performed to evaluate and compare muscle activity abnormalities between the two groups.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The study showed a higher incidence of abnormal masticatory muscle activity in habitual resting position in TMD without ST patients compared to those with TMD and ST. A statistically significant difference in muscle activity between the two groups was observed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The results suggest a potential link between masticatory muscle activity and tinnitus in TMD patients. Neuroplasticity may play a role in modulating the psychoacoustic characteristics of tinnitus.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"11 4","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cre2.70172","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144615393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}