{"title":"The Association of Matrix Metalloproteinase-1, -2, -3, -7, and -13 Gene Polymorphisms With Peri-Implantitis in an Iranian Population: A Case–Control Study","authors":"Leila Saremi, Soheil Shahbazi, Mohammad Ebrahim Ghaffari, Saharnaz Esmaeili, Shirin Lotfipanah, Reza Amid, Mahdi Kadkhodazadeh","doi":"10.1002/cre2.70049","DOIUrl":"https://doi.org/10.1002/cre2.70049","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Peri-implantitis (PI) is the most common biological issue surrounding dental implants. According to current knowledge, the aforementioned complication is not equally distributed across different populations, and gene polymorphisms might be one contributing factor. The current study aimed to examine the association between gene polymorphisms of matrix metalloproteinase- (MMP-) 1, -2, -3, -7, and -13 with PI in an Iranian demographic.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>The study's sample included 50 subjects suffering from PI and 89 healthy controls. From each participant, a venous blood sample of 5 cc was obtained, and DNA was extracted. Gene polymorphisms were investigated using restriction fragment length polymorphism polymerase chain reaction (RFLP-PCR) combined with electrophoresis. Statistical analyses were done using the Pearson chi-square test, odds ratio, and <i>t</i>-test via SPSS version 28.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The MMP-3 (-1171 5A/6A) and MMP-7 (-181 A/G) gene polymorphisms were significantly different between the patients with PI and healthy controls (PV < 0.001 and =0.025, respectively). MMP-1 (-1607 1G/2G), MMP-2 (-1306 C/T), and MMP-13 (-77 A/G) gene polymorphisms did not, however, differ in terms of prevalence between the two groups (PV > 0.05). Moreover, the presence of the 6 A allele in the MMP-3 (-1171 5A/6A) genotype resulted in a significant decrease in PI risk (PV < 0.001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Gene polymorphisms in the genotypes of MMP-3 (-1171 5A/6A) and MMP-7 (-181 A/G) were differential when comparing PI patients and healthy controls of the studied population.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"10 6","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cre2.70049","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142749022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kristina Bertl, Mohammad Al-Said, Ahmed Mourad, Magdalena Mayol, Zita Lopes da Silva, Evaggelia Papia, Andreas Stavropoulos
{"title":"Reduced Biofilm Accumulation on Implants Treated With Implantoplasty—An In Situ Trial With a Within-Subject Comparison","authors":"Kristina Bertl, Mohammad Al-Said, Ahmed Mourad, Magdalena Mayol, Zita Lopes da Silva, Evaggelia Papia, Andreas Stavropoulos","doi":"10.1002/cre2.70043","DOIUrl":"https://doi.org/10.1002/cre2.70043","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>This study aimed to evaluate potential differences in biofilm accumulation on three different implant surfaces: turned surface (TS), modified surface (MS), and modified surface treated with implantoplasty (IPS), using a within-subject comparison.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>Ten volunteers wore individualized splints containing three titanium implants with different surfaces (TS, MS, and IPS) on each buccal side of the splint. The implant position (anterior, central, and posterior) was randomly assigned among the three implants on each side. Volunteers were instructed to wear the splint for 72 h and to remove it only for eating, drinking, and performing standard oral hygiene; the splint itself was not cleaned. After 72 h, the implants were carefully removed from the splint, and the accumulated biofilm was assessed using a crystal violet assay by measuring intensity/absorbance at 570 nm.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>All volunteers reported no deviations from the instructions. The lowest mean amount of biofilm (0.405 ± 0.07) was detected on implants of the IPS group, followed by implants of the MS (0.463 ± 0.06) and TS group (0.467 ± 0.07). A multilevel mixed-effects linear regression analysis confirmed that implants of the IPS group accumulated a significantly lower amount of biofilm than the other surfaces (<i>p</i> < 0.001); however, no significant difference was detected between implants of the TS and MS groups (<i>p</i> = 0.806).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Implantoplasty can generate a surface significantly less conducive to biofilm accumulation in the short term compared to pristine implants with turned or modified surfaces.</p>\u0000 \u0000 <p><b>Trial Registration</b>: clinicaltrials.gov identifier: NCT06049121.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"10 6","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cre2.70043","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142749020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of Bone Density for Primary Implant Stability Using a Newly Designed Drill: An In Vitro Study on Polyurethane Bone Blocks","authors":"Kaien Wakamatsu, Kazuya Doi, Reiko Kobatake, Yoshifumi Oki, Kazuhiro Tsuga","doi":"10.1002/cre2.70048","DOIUrl":"https://doi.org/10.1002/cre2.70048","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Bone density is an important factor for long-term implant success. Peri-implant bone density evaluation before implant placement can be useful for treatment planning, such as the selection of proper implant size or drilling protocol in each case. In this study, we aimed to establish an objective intraoperative bone density evaluation method by measuring the drilling torque value using a newly designed density measurement drill.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>Drilling torque value measurement was performed intraoperatively using three types of drills; two previously reported drills and a newly designed drill as a density measurement drill. Polyurethane bone blocks of different densities (D1–D4) were used in this experiment. After the measurement, implants were inserted based on the scheduled plan, and insertion torque (IT) and implant stability quotient (ISQ) were measured to assess primary implant stability.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The drilling torque value increased with the bone blocks' density, and there were significant differences among different densities in all groups (<i>p</i> < 0.05). The drilling torque value showed a positive correlation with IT in all groups (<i>p</i> < 0.05). In addition, the drilling torque value increased with the increase in ISQ in all groups.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Within the limitations of this study, a newly designed density measurement drill was able to classify D1–D4 in polyurethane bone blocks despite its narrow diameter, and an objective intraoperative bone evaluation can be achieved. An intraoperative assessment of the drilling torque value can predict primary implant stability and provide valuable information for intraoperative treatment planning, such as undersized drilling protocol and implant size change.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"10 6","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cre2.70048","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142749021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wei Chen, Monisha Dhawan, Jonathan Liu, Damie Ing, Kruti Mehta, Daniel Tran, Daniel Lawrence, Max Ganhewa, Nicola Cirillo
{"title":"Mapping the Use of Artificial Intelligence–Based Image Analysis for Clinical Decision-Making in Dentistry: A Scoping Review","authors":"Wei Chen, Monisha Dhawan, Jonathan Liu, Damie Ing, Kruti Mehta, Daniel Tran, Daniel Lawrence, Max Ganhewa, Nicola Cirillo","doi":"10.1002/cre2.70035","DOIUrl":"10.1002/cre2.70035","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Artificial intelligence (AI) is an emerging field in dentistry. AI is gradually being integrated into dentistry to improve clinical dental practice. The aims of this scoping review were to investigate the application of AI in image analysis for decision-making in clinical dentistry and identify trends and research gaps in the current literature.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>This review followed the guidelines provided by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews (PRISMA-ScR). An electronic literature search was performed through PubMed and Scopus. After removing duplicates, a preliminary screening based on titles and abstracts was performed. A full-text review and analysis were performed according to predefined inclusion criteria, and data were extracted from eligible articles.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Of the 1334 articles returned, 276 met the inclusion criteria (consisting of 601,122 images in total) and were included in the qualitative synthesis. Most of the included studies utilized convolutional neural networks (CNNs) on dental radiographs such as orthopantomograms (OPGs) and intraoral radiographs (bitewings and periapicals). AI was applied across all fields of dentistry - particularly oral medicine, oral surgery, and orthodontics - for direct clinical inference and segmentation. AI-based image analysis was use in several components of the clinical decision-making process, including diagnosis, detection or classification, prediction, and management.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>A variety of machine learning and deep learning techniques are being used for dental image analysis to assist clinicians in making accurate diagnoses and choosing appropriate interventions in a timely manner.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"10 6","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cre2.70035","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142726465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mario Dioguardi, Davide La Notte, Diego Sovereto, Cristian Quarta, Andrea Ballini, Vito Crincoli, Riccardo Aiuto, Mario Alovisi, Angelo Martella, Lorenzo Lo Muzio
{"title":"Exploring the Impact of Access Cavity Designs on Canal Orifice Localization and Debris Presence: A Scoping Review","authors":"Mario Dioguardi, Davide La Notte, Diego Sovereto, Cristian Quarta, Andrea Ballini, Vito Crincoli, Riccardo Aiuto, Mario Alovisi, Angelo Martella, Lorenzo Lo Muzio","doi":"10.1002/cre2.70013","DOIUrl":"10.1002/cre2.70013","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>One of the primary objectives in endodontics is to achieve thorough cleaning and disinfection of the root canal system during an endodontic procedure. This aims to reduce microbial contamination and prevent the development of endodontic lesions. To attain this goal, it is imperative to establish access to the endodontic space that allows for the complete removal of pulp tissue and the accurate identification of canal orifices while preserving the anatomical integrity of the root floor and pulp chamber as much as possible. In this scoping review, we aim to explore aspects related to the identification of canal orifices and the presence of pulp debris and residues during endodontic treatment. Specifically, we aim to assess whether and to what extent the design of the access cavity impacts these factors.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>The scoping review was conducted and prepared following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines (PRISMA Extension for Scoping Reviews [PRISMA-ScR]).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The search yielded a total of 3697 bibliographic sources. After eliminating duplicates and applying eligibility criteria, only 10 studies were included.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>In conclusion, our review, conducted following PRISMA guidelines, includes 10 studies and suggests a potential trend: conservative techniques may generate more debris, whereas guided techniques exhibit superior precision in locating canal openings.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"10 6","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cre2.70013","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142692567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Influence of Patient-, Site-, and Implant-Related Factors on Marginal Bone Levels of Dental Implants in a Rural Population in China: A Retrospective Study","authors":"Anahat Khehra, Ossi Zanner, Nachum Samet, Liran Levin","doi":"10.1002/cre2.70045","DOIUrl":"10.1002/cre2.70045","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Limited research is available on implant treatment outcomes in rural populations. This may be due to the presence of various barriers, such as access to oral health care, resources, health literacy, and education. The aim of this study was to evaluate the influence of patient-, site-, and implant-related factors on marginal bone levels of dental implants in a rural population in China.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>A retrospective study was conducted using data from a private dental office. Subjects included in this study received dental implants as part of their routine dental treatment. Information on age, gender, smoking status, diabetes, heart disease, jaw location, restorative type, loading protocol, survival rate, implant length, and diameter was collected. Marginal bone loss was recorded as the largest value at either the mesial or distal aspect on peri-apical radiographs. Descriptive and inferential statistics were performed along with linear regression analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Overall, 428 implants were placed in 90 subjects over an average follow-up period of 453 days. No implant failures were recorded. The average marginal bone loss was 0.10 mm, with 80.6% of implants showing no marginal bone loss. The extent of marginal bone loss was greater in the mandible (0.13 ± 0.25) than in the maxilla (0.08 ± 0.19). An increase in implant diameter by 1 mm resulted in 0.08 mm of marginal bone loss, indicating wider diameter implants are associated with more bone loss. Age was also positively correlated with marginal bone loss, increasing by 0.002 mm per year. No differences were found for gender, smoking, diabetes, heart disease, restoration type, and immediate loading.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Dental implant therapy in a rural Chinese population demonstrated high survival rates and minimal marginal bone loss. Factors such as age, implant location, and diameter influenced bone loss. This study fills a critical gap in understanding implant outcomes specifically within rural settings, highlighting the need for tailored approaches to enhance patient access and care in these communities. Further research is needed to explore these relationships and assess implant outcomes in rural populations.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"10 6","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11582925/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142686247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Understanding Occlusion and Temporomandibular Joint Function Using Deep Learning and Predictive Modeling","authors":"Taseef Hasan Farook, James Dudley","doi":"10.1002/cre2.70028","DOIUrl":"https://doi.org/10.1002/cre2.70028","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Advancements in artificial intelligence (AI)-driven predictive modeling in dentistry are outpacing the clinical translation of research findings. Predictive modeling uses statistical methods to anticipate norms related to TMJ dynamics, complementing imaging modalities like cone beam computed tomography (CBCT) and magnetic resonance imaging (MRI). Deep learning, a subset of AI, helps quantify and analyze complex hierarchical relationships in occlusion and TMJ function. This narrative review explores the application of predictive modeling and deep learning to identify clinical trends and associations related to occlusion and TMJ function.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Debates persist regarding best practices for managing occlusal factors in temporomandibular joint (TMJ) function analysis while interpreting and quantifying findings related to the TMJ and occlusion and mitigating biases remain challenging. Data generated from noninvasive chairside tools such as jaw trackers, video tracking, and 3D scanners with virtual articulators offer unique insights by predicting variations in dynamic jaw movement, TMJ, and occlusion. The predictions help us understand the highly individualized norms surrounding TMJ function that are often required to address temporomandibular disorders (TMDs) in general practice.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Normal TMJ function, occlusion, and the appropriate management of TMDs are complex and continue to attract ongoing debate. This review examines how predictive modeling and artificial intelligence aid in understanding occlusion and TMJ function and provides insights into complex dental conditions such as TMDs that may improve diagnosis and treatment outcomes with noninvasive techniques.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"10 6","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cre2.70028","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142674061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of Panoramic Radiography Diagnostic Accuracy in the Assessment of Interdental Alveolar Bone Loss Using CBCT","authors":"Najmeh Anbiaee, Pedram Pahlavanzadeh","doi":"10.1002/cre2.70042","DOIUrl":"https://doi.org/10.1002/cre2.70042","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Alveolar bone loss (ABL) and periodontal lesions are common diseases that have an undeniable effect on teeth maintenance and health. Current diagnostic methods include probing, intraoral radiography, and panoramic radiography; each has its limitations. In this study, we aimed to assess the diagnostic accuracy of panoramic radiography in the diagnosis of interdental ABL.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>In this cross-sectional study, panoramic and cone-beam computed tomography (CBCT) images from 80 patients were collected from the archives of an oral and maxillofacial radiology center. The amount of ABL was obtained by measuring the distance from the Cemento-Enamel Junction (CEJ) to the alveolar bone crest on both panoramic and CBCT images. Patients were divided into healthy (ABL ≤ 2 mm) and diseased (2 mm < ABL) groups in terms of periodontal disease.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>There was no statistically significant difference in the average ABL in the premolar, maxillary molar, and mandibular molar areas between the two techniques. However, in other areas, the ABL size was significantly lower in the panoramic view (<i>p</i> < 0.05). Also, the panoramic technique correctly recognized 89.1% of normal and 88.4% of ABL cases. The overall accuracy of panoramic radiography in the diagnosis of ABL was 85%, indicating the good accuracy of this technique. In maxilla, the highest diagnostic accuracy of the panoramic technique was in the molars, and the lowest was in the incisors. In the mandible, the highest and lowest diagnostic accuracy of the panoramic technique was related to molars and premolars, respectively. According to the kappa statistic, there was a significant good to very good agreement between the two types of techniques in all maxillary areas (<i>p</i> < 0.001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Panoramic radiography is accurate in showing ABL. Measuring ABL in the posterior mandibular areas in panoramic radiographs is quite reliable; however, in general, digital panoramic radiography shows less ABL than the actual amount.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"10 6","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cre2.70042","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142674062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Higher Prevalence of Tooth Loss in People With Abdominal Obesity but Normal Weight: Findings From the United States and Scottish Populations","authors":"Jing Kang, Harriet Larvin, Sue Pavitt, Jianhua Wu","doi":"10.1002/cre2.70047","DOIUrl":"https://doi.org/10.1002/cre2.70047","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Previous research has shown that people with obesity are at a higher risk of tooth loss; however, it is unclear whether abdominal obesity (e.g., high waist circumference) is associated with tooth loss among individuals without obesity. This study aims to investigate the association between abdominal obesity and tooth loss among people who are not obese.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>Two cross-sectional surveys were used: the United States' National Health and Nutrition Examination Survey (NHANES) 1999–2012 (<i>n</i> = 19,436) and the Scottish Health Survey (SHeS) 2008–2014 (<i>n</i> = 4243). Tooth loss was measured by the number of remaining teeth: 20 and over, 1–19, and edentulous. Abdominal obesity was defined by categorizing waist circumference into three levels: normal, high, and very high. Ordinal logistic regression was used to model the association between tooth loss and abdominal obesity.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>For people living without obesity, abdominal obesity is associated with a higher prevalence of tooth loss, and the effect is different between women and men. For women, abdominal obesity increased the chance of tooth loss by 64% (odds ratio [OR]: 1.64, 95% confidence interval [CI]: 1.16–2.34) in the NHANES and 196% (OR: 2.96, 95% CI: 1.47–5.97) in the SHeS. For men, abdominal obesity increased the chance of tooth loss by 41% (OR: 1.41, 95% CI: 1.06–1.87) in the NHANES and 65% (OR: 1.65, 95% CI: 1.02–2.73) in the SHeS.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>This study indicated that the prevalence of tooth loss is substantially higher in people with abdominal obesity, and this association is distinctively different between men and women. These findings suggest that those who are not obese but have abdominal obesity may be an important target population for oral health prevention strategies.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"10 6","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cre2.70047","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142674063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Prediction Model for Lymph Node Metastasis of Oral Squamous Cell Carcinoma Based on Multiple Risk Factors","authors":"Hongyu Shen, Tonghan Zhang, Shuoyu Wang","doi":"10.1002/cre2.70046","DOIUrl":"10.1002/cre2.70046","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Cervical lymph node metastasis (CLNM) frequently occurs in oral cancer patients. This study aims to investigate risk factors associated with CLNM and predict CLNM preoperatively in patients with oral squamous cell carcinoma (OSCC).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>This population-based, hospital retrospective cohort study included 158 patients with oral cancer. We performed regression analysis to determine risk factors and establish a model for predicting CLNM in patients with OSCC. To distinguish and validate the prediction model, we used the area under the receiver operating characteristic (ROC) curve (AUC).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Lymph node size, tumor size, degree of differentiation, and LVI were risk factors for cancer metastasis. The OR values were 1.245, 2.847, 2.527, and 6.945, respectively. The AUC value for the clinical prediction model was 0.8736 (95% CI: 0.8043–0.9429).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The prediction model for OSCC patients predicts CLNM and provides a new method for preoperative assessment of whether cervical lymph nodes are metastatic, as well as a guide for surgical treatment, including whether to carry out neck dissection and which neck dissection procedure to use.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"10 6","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cre2.70046","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142646956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}