Next Nanotechnology最新文献

{"title":"Advancements in nanotechnology for enhancing the efficiency of advanced oxidation processes: A review","authors":"Ka Kin Wang,&nbsp;Pui Vun Chai","doi":"10.1016/j.nxnano.2025.100353","DOIUrl":"10.1016/j.nxnano.2025.100353","url":null,"abstract":"<div><div>Water deterioration has become increasingly severe due to industrialization and the growth of human populations. Different types of emerging pollutants have also created immense stress on the environment, with some showing strong resistance to conventional biological treatment systems. As a result, more sophisticated water and wastewater treatment technologies are required to ensure safe and reliable water supplies. Advanced oxidation processes (AOPs) have proven effective by generating strong reactive oxygen species, such as hydroxyl radicals, that can degrade highly resistant pollutants. These radicals may be produced through ultraviolet radiation, ultrasound, or electric power in the presence of appropriate catalysts. Incorporating nanotechnology as a catalyst in AOPs offers significant advantages, as nanomaterials exhibit high stability, large surface area, strong reactivity, and recyclability. Such properties not only enhance the purification of water for human and environmental health but also reduce the reliance on chemical additives, improve energy efficiency, and promote the sustainable use of resources. Collectively, these advances contribute to cleaner water access, more responsible treatment practices, and a lower environmental footprint that supports both ecosystem protection and climate resilience.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"9 ","pages":"Article 100353"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145799876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Directional heat rectification in electronic logic circuits via near-field radiative heat transfer","authors":"Stephanie Yen Nee Kew,&nbsp;Aaron Edward Sheng Jye Teo","doi":"10.1016/j.nxnano.2026.100506","DOIUrl":"10.1016/j.nxnano.2026.100506","url":null,"abstract":"<div><div>As electronic devices become increasingly compact and integrated, conventional heat dissipation techniques are proving insufficient, posing challenges to device longevity and performance. In this review, the state-of-the-art approach to nanoscale temperature management, near-field radiative heat transfer (NFRHT), is examined to explore the emerging concept of heat rectification in electronic logic circuits. Despite growing interest in NFRHT, most studies have primarily focused on geometric refinement and heat flux amplification, with limited attention to its functional integration within logic circuits. This review synthesizes recent advancements in leveraging NFRHT for directional control of heat flow, providing a comprehensive perspective on strategies for transforming nanoscale heat regulation. NFRHT performance can be significantly enhanced through strategic material selection, structural asymmetry, and nanoscale gap control, enabling its integration into advanced logic components such as phononic gates, rectifiers, switches, and thermotronic diodes. Representative studies report rectification efficiencies of up to 93% using materials such as Bi₂Se₃, vanadium dioxide (VO₂), gold, and doped silicon in sub-100-nm gaps. With its capacity to regulate heat currents, NFRHT offers promising avenues for mitigating localized overheating and improving the energy efficiency of logic devices. The review concludes by highlighting how NFRHT-driven heat rectification can address challenges related to materials variability and gap control while proposing future research directions for advanced carbon-based thermo-logic devices.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"9 ","pages":"Article 100506"},"PeriodicalIF":3.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148523550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring mango (Mangifera indica) fruit peel extract mediated bio-preparation of CuO nanoparticles for biological, dye degradation and sensor applications","authors":"Hannah Numa ,&nbsp;T.M. Sharanakumar ,&nbsp;Lydia Yalambing ,&nbsp;T. Naveen Kumar ,&nbsp;K.V. Anasuya ,&nbsp;C.R. Ravikumar ,&nbsp;H.C. Ananda Murthy","doi":"10.1016/j.nxnano.2025.100356","DOIUrl":"10.1016/j.nxnano.2025.100356","url":null,"abstract":"<div><div>Green nanotechnology offers a sustainable, cost-effective, and environmentally beneficial way to create nanoparticles from organic materials rather than raw ones. Specifically, bio-waste such as fruit peels can be utilized to synthesize nanoparticles by extraction of their beneficial biomolecules. The present research reveals the green synthesis approach to produce copper oxide nanoparticles for antibacterial application by using the aqueous mango (<em>Mangifera indica</em>) (MGI) peel extract. The phytochemical testing of mango peel extract confirmed the presence of tannins, polyphenols, alkaloids, saponins, flavonoids, terpenoids, reducing sugars, and glycosides. The UV–visible and UV-DRS studies showed the maximum absorbance and energy gap value as 425 nm and 2.08 eV, respectively. The XRD pattern confirmed the formation of crystalline CuO NPs with a tenorite structure. The scanning electron microscopy confirmed nearly spherical CuO NPs. The antibacterial efficacy of the green CuO NPs was evaluated against the Gram-positive <em>Bacillus Cereus</em> and Gram-negative <em>Escherichia coli</em> bacteria. The maximum zone of inhibition of 11.6 mm was recorded for the calcined CuO NPs against the Gram-positive bacterial strain <em>Bacillus Cereus</em>. The synthesized CuO NPs proved to be potential candidates as antibacterial agents. The CuO NPs were also used for the sensor studies of lithium. The modified electrode's electrocatalytic response for Li sensing was found to be extremely concentration sensitive, as the anodic oxidation current rose progressively with the concentration of Li. The photocatalytic degradation study of Fast Orange dye revealed an absorbance at 495 nm during the time period of 90 min and exhibits a maximum percentage of 74 % absorbance value. The synthesized green CuO NPs proved to have multifunctional nature for futuristic applications.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"9 ","pages":"Article 100356"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145799936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Impact of bridging the gap between Artificial Intelligence and nanomedicine in healthcare” [Next Nanotechnol. 8 (2025) 100203]","authors":"Divyam Mishra ,&nbsp;Bhavishya Chaturvedi ,&nbsp;Vishal Soni ,&nbsp;Dhairya Valecha ,&nbsp;Megha Goel ,&nbsp;Jamilur R. Ansari","doi":"10.1016/j.nxnano.2025.100347","DOIUrl":"10.1016/j.nxnano.2025.100347","url":null,"abstract":"","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"9 ","pages":"Article 100347"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145799934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multifaceted graphene-based materials for comprehensive environmental sustainability","authors":"Prashant H. Gohil ,&nbsp;Gopal Avashthi","doi":"10.1016/j.nxnano.2025.100348","DOIUrl":"10.1016/j.nxnano.2025.100348","url":null,"abstract":"<div><div>Graphite (Gt) derived graphene (Gr) and its exceptional mechanical strength, thermal conductivity and electrical properties make it a revolutionary material for 21st-century environmental technologies. This review focuses on the synthesis, functionalization and environmental remediation of graphene oxide (GO), reduced graphene oxide (rGO) and their derivatives for wastewater purification, pollutants adsorption, catalysis and sensing applications under controlled pH, temperature, and ionic strength. Hydrophilic surface of GO with oxygen functionalities enables strong electrostatic interactions with neonicotinoids of adsorption capacities 3.11 mg/g, ciprofloxacin of 500 mg/g, Zn(II) of 345 mg/g and Methylene blue of 450 mg/g for removing cationic impurities. Also, rGO efficiently removes cationic pollutants such as As(III), As(V) and Cr(VI), while functionalized graphene aerogel (fGA) shows recyclability along with improved oil, dyes and solvent adsorption. The microalgae Galdieria sulphuraria achieved 71 % COD, 80 % BOD and 66 % FOG reduction in restaurants’ wastewater with significant nutrient uptake of 96 % NH⁴⁺-N and 99 % TP removal which highlights bio-integrated remediation potential. Photocatalysts GO-TiO₂ and Ni-GO composites examined improved hydrogen evolution up to sevenfold, while rGO-TiO₂ photocatalyst generate reactive oxygen species for pollutants mineralization. Gr-based electrochemical sensors detect Hg²⁺ as low as 0.6 nM and Pb²⁺ at 5ppb, demonstrating ultrahigh sensitivity. So, Gr-based nanocomposites offer sustainable sensing, though scalable green synthesis. However, safety regulations remain essential for large-scale deployment.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"9 ","pages":"Article 100348"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145799940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Percutaneous permeation, distribution and absorption of quantum dots","authors":"Varsha Sahu,&nbsp;Sunit Kumar Sahoo","doi":"10.1016/j.nxnano.2026.100368","DOIUrl":"10.1016/j.nxnano.2026.100368","url":null,"abstract":"<div><div>Quantum dots are one of the most developing semiconductor fluorescent nanoparticles, which are widely used in biomedical sciences. Their nano size, large surface area, biocompatibility, unique optical and physicochemical properties are appropriate for a various purposes including treatment, drug delivery, sensing, imaging and diagnosis. Till date, several researches performed on the properties and applications of quantum dots but there is very little evidence about their route of administration. In general, quantum dots are administered in the biological system through intravenous, intramuscular, and inhalation routes, but there is very little evidence of the percutaneous permeation of quantum dots, which limits their use in skin diseases. Drug delivery through the skin is a preferable route for the treatment of skin disease because it is non-invasive, avoid the first-pass metabolism effect, prevents the drug from enzymatic degradation, and provides targeted or sustainable release. Therefore, this review focuses on quantum dots and their percutaneous absorption within the skin. This study summarizes the percutaneous permeation and distribution of quantum dots via different pathways. It also includes available relevant articles that provide a new aspect to quantum dots and their delivery in the skin to facilitate medication therapy for several skin conditions, including psoriasis, eczema, inflammation, infections, wound healing, skin cancer, and cosmetology.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"9 ","pages":"Article 100368"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146078067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Green synthesis and molecular-level mechanism of silver nanoparticles from Pandanus fascicularis (Keya) leaf extract with antibacterial activity","authors":"Sultana Bedoura ,&nbsp;ABM Habibullah,&nbsp;Md. Shohidul Islam,&nbsp;Md. Mahfuze Ahmed Mahin,&nbsp;Muhammad Taushif Anwar,&nbsp;Mahfuza Tahsin Shoily","doi":"10.1016/j.nxnano.2026.100376","DOIUrl":"10.1016/j.nxnano.2026.100376","url":null,"abstract":"<div><div>With the global rise in multidrug-resistant bacteria, there is a critical need for sustainable antimicrobial agents. Silver nanoparticles (AgNPs) synthesized via plant extracts offer an eco-friendly and efficient approach, yet many phytochemical-rich plant sources remain underexplored. This study reports, for the first time, the green synthesis of AgNPs using <em>Pandanus fascicularis</em> (Keya) leaf extract—an indigenous coastal plant abundant in bioactive compounds. The synthesized AgNPs were characterized by UV-Vis spectroscopy, laser diffraction particle size analysis, and transmission electron microscopy (TEM), confirming their nanoscale size (20–25 nm), spherical morphology, and good colloidal stability. The AgNPs exhibited strong antibacterial activity against <em>Staphylococcus aureus</em> and <em>Escherichia coli</em>, with inhibition zones of 15 mm and 12 mm, respectively. To elucidate the molecular mechanism of nanoparticle formation, density functional theory (DFT) calculations were performed on representative phytochemicals (gallic acid and <span>D</span>-glucose) interacting with Ag⁺. The computational results confirmed spontaneous complex formation via oxygen donor atoms, supported by vibrational shifts, frontier orbital interactions, and binding energy estimations. Atoms-in-molecules (AIM) and natural bond orbital (NBO) analyses further revealed weak but stabilizing Ag–O coordination with partial covalent character, particularly stronger in gallic acid. Although modeled using a simplified 1:1 metal–ligand framework, these insights support the dual role of phytochemicals as reducing and stabilizing agents in AgNP synthesis. Together, the experimental and computational findings demonstrate that <em>P. fascicularis</em> extract is a promising and sustainable source for green AgNP production, with potential antimicrobial and biomedical applications.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"9 ","pages":"Article 100376"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146078066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced targeted delivery of cisplatin via folate and boron-modified magnetic nanoparticles: A promising approach for cervical cancer treatment","authors":"Popsy Raj ,&nbsp;Manoj M. Gadewar ,&nbsp;Prashanth Gopala Krishna ,&nbsp;Debashish Paramanick ,&nbsp;Srilatha Rao ,&nbsp;Lalithamba Haraluru Shankaraiah ,&nbsp;N.P. Bhagya","doi":"10.1016/j.nxnano.2025.100352","DOIUrl":"10.1016/j.nxnano.2025.100352","url":null,"abstract":"<div><div>This study aims on the development and evaluation of cisplatin-loaded nanoparticles (NPs) modified with folate (FA) and boron to enhance targeted drug delivery and therapeutic efficacy. FA and boron were employed as targeting ligands, while aldehyde sodium alginate (ASA) was used as a stabilizing modifier to improve the surface activity and stability of magnetic Fe₃O₄ nanoparticles synthesized via chemical co-precipitation. FA and boron were activated through interaction with NH₂-PEG-NH₂, through non-covalent chemical bonding, forming stable and water-soluble complexes. ASA was combined to Fe₃O₄ NPs after FA-PEG linkage via Schiff base formation. Subsequent substitution of chloride in cisplatin with the hydroxyl group of ASA yielded FA- and ASA-modified CIS-FA-ASA-MNPs, along with boron-coated counterparts. MTT assays demonstrated that cisplatin-loaded NPs significantly reduced cancer cell viability compared to other formulations, with CIS-loaded boron-coated NPs exhibiting pronounced cytotoxicity even at lower doses. The IC₅₀ value of CIS-loaded boron-coated NPs (0.61 µg/mL) was markedly lower than that of CIS-loaded FA-coated NPs (0.65 µg/mL) and free cisplatin (1.25 µg/mL), confirming superior anticancer potential. Enhanced apoptosis was observed due to improved nanocarrier internalization by CIS-loaded boron-coated NPs. These results highlight the promise of boron-coated, cisplatin-loaded NPs as a targeted therapeutic strategy for cervical cancer. The enhanced cytotoxicity compared with conventional formulations is attributed to improved cellular uptake and controlled drug release. Further in vivo and biological studies are warranted to validate the therapeutic efficacy and safety of this novel delivery system.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"9 ","pages":"Article 100352"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145840922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis of 2,3-Naphthalocyanine/ nickel hydroxide (2,3-Nc/Ni(OH)2) nanocomposite for uric acid electrochemical sensing","authors":"Omolola E. Fayemi ,&nbsp;Saheed E. Elugoke ,&nbsp;Funmilola Adesanya","doi":"10.1016/j.nxnano.2026.100377","DOIUrl":"10.1016/j.nxnano.2026.100377","url":null,"abstract":"<div><div>The sensitive and selective detection of uric acid (UA) is crucial for the early diagnosis of several neurological diseases/disorders in the human body. In this study, nickel hydroxide (Ni(OH)₂ nanoparticles were synthesized using a wet chemical method and doped with 2,3-Naphthalocyanine (2,3-Nc) to form 2,3-Nc/Ni(OH)₂ nanocomposite for the detection of UA. The morphologies of the synthesized nanomaterials were investigated using transmission electron microscopy (TEM) and scanning electron microscopy (SEM) equipped with energy-dispersive X-ray spectroscopy (EDS), confirming the successful formation of the nanostructures. UV–visible spectroscopy (UV) was used to ascertain the optical characteristics of the nanocomposite. Fourier transform infrared spectroscopy (FTIR) identified the functional groups present, while X-ray diffraction (XRD) analyses validated the crystallinity of the synthesized nanomaterials. The UA sensors were fabricated by depositing Ni(OH)₂, 2,3-Nc, and 2,3-Nc/Ni(OH)₂ nanocomposite onto the screen-printed gold electrode (SPAuE). Cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), and square wave voltammetry (SWV) were used to evaluate the UA electrochemical sensing performance of the bare SPAuE, SPAuE/2,3-Nc, SPAuE/Ni(OH)₂, and SPAuE/2,3-Nc/Ni(OH)₂ electrodes. Using SWV, the SPAuE/2,3-Nc/Ni(OH)₂ electrode achieved a low limit of detection (LOD) of 14.16 μM with a linear range of 7.65 μM to 513.67 μM. The sensor’s selectivity and stability were also assessed. The applicability of the UA sensor was tested in spinach and baked beans samples through standard addition and recovery of known UA concentration. The high sensitivity of the porous 2,3-Nc/Ni(OH)₂ nanocomposite highlights its potential for the sensing of other biomolecules.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"9 ","pages":"Article 100377"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146187331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nanostructured lipid carriers for topical drug delivery: A comprehensive review of design, mechanisms, and therapeutic advances","authors":"Mamta Kumari ,&nbsp;Dipti Gohil ,&nbsp;Piyushkumar Sadhu","doi":"10.1016/j.nxnano.2026.100367","DOIUrl":"10.1016/j.nxnano.2026.100367","url":null,"abstract":"<div><div>Nanostructured Lipid Carriers (NLCs) represent a significant advancement in topical drug delivery, overcoming key limitations of earlier lipid-based systems such as Solid Lipid Nanoparticles (SLNs). By combining solid and liquid lipids into a nanometric matrix, NLCs enhance drug entrapment, increase loading capacity, and provide greater stability. These properties support improved skin permeation, controlled release, and targeted delivery to deeper skin layers, thereby minimizing systemic side effects. This review critically examines the scientific foundation and formulation strategies of NLCs, including their composition, classification, and manufacturing methods. It highlights the influence of lipid and surfactant selection on physicochemical parameters such as particle size, zeta potential, and entrapment efficiency. Detailed mechanisms of drug release and skin penetration through intercellular, transcellular, and trans-appendageal pathways are explored, alongside the role of NLCs in forming occlusive films that enhance skin hydration and barrier repair. The review also evaluates the therapeutic efficacy of NLCs in treating inflammatory disorders, fungal infections, and chronic dermatological conditions based on preclinical and clinical studies. NLCs offer promising advantages in topical therapy, including superior bioavailability, sustained drug retention, and enhanced patient compliance. Their integration with precision medicine and cosmetic dermatology marks them as next-generation carriers for safe and effective topical drug delivery.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"9 ","pages":"Article 100367"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145977882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}