Next Nanotechnology最新文献

{"title":"Properties of natural hydroxyapatite prepared by pressureless sintering using different temperatures and holding times","authors":"Nuradeen Idris ,&nbsp;Bashar Dan-Asabe ,&nbsp;Semiyou A. Osseni ,&nbsp;Kazeem O. Rabiu ,&nbsp;Adetunji R. Sowunmi ,&nbsp;Naresh D. Bansod ,&nbsp;Frantisek Lukac ,&nbsp;Stefan Csaki ,&nbsp;David O. Obada","doi":"10.1016/j.nxnano.2025.100168","DOIUrl":"10.1016/j.nxnano.2025.100168","url":null,"abstract":"<div><div>The sintering behavior of hydroxyapatite (HAp) particles prepared via pressureless sintering was investigated. The powders were subjected to different sintering temperatures of 900°C and 1000°C for 2, 4, and 6 hours (hr). The sintered HAp powders were analyzed for phase stability, density, Vickers hardness, fracture toughness, brittleness index, and in vitro biological properties. XRD analysis indicated HAp as the dominant phase in all samples. Rietveld refinement quantified the weight percent (wt.%) of HAp to be equal to or more than 97 % in all samples. Scanning electron microscopy (SEM) analyses revealed larger and flattened particle shapes for HAp sintered at 1000°C and this influenced the mechanical properties of the samples. The density of the HAp samples was close to the theoretical density of HAp. Samples sintered with 4-hr holding times displayed greater stability in physiological fluids. In vitro degradation tests in phosphate buffer saline (PBS) under physiological conditions revealed minimal weight loss and stable pH levels over 14 days. This indicates the scaffolds’ potential for long-term physiological stability. Overall, samples sintered at 900°C may be further investigated to enhance their significance in biomedical applications.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"7 ","pages":"Article 100168"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143854821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the liposomal encapsulation and enhanced cytotoxicity of selenium nanoparticles against lung cancer cells","authors":"Dipti Chirakara ,&nbsp;Shriya Lotlikar ,&nbsp;Mahalakshmi Nannan ,&nbsp;Nageswara Rao Dunna ,&nbsp;Sivaramakrishnan Venkatabalasubramanian","doi":"10.1016/j.nxnano.2024.100121","DOIUrl":"10.1016/j.nxnano.2024.100121","url":null,"abstract":"<div><div>Lung cancer is unequivocally the most common cause of cancer-related deaths, surpassing all other types of cancer in terms of mortality rates among both men and women. Although surgery, chemotherapy, and radiation therapy are common treatments, they carry significant risks to healthy cells. The versatile benefits of using lipid-based nanocarrier systems in healthcare, combined with the therapeutic and supportive properties of micronutrients like selenium, have led to the investigation of encapsulating selenium nanoparticles in liposomes (Lip-SeNPs) as a new therapeutic strategy. Using scanning electron microscope-energy dispersive X-ray spectroscopy (SEM-EDS), dynamic light scattering (DLS), X-ray diffraction (XRD) and Fourier-transform infrared spectroscopy (FTIR), the characterisation and stability of the Lip-SeNPs were compared with liposome-free SeNPs. This was followed by their cytotoxicity evaluation against lung cancer cells. The DLS results showed that the synthesised liposome-free SeNPs and Lip-SeNPs were spherical, with size distribution of around 151.2 and 163 nm. The zeta potential values were determined for Lip-SeNPs (-15.7 mV) compared to liposome-free SeNPs (-5.71 mV). FTIR analysis of SeNPs and Lip-SeNPs confirmed valuable information about their surface chemistry and potential structure functionalisation avenues. The augmented results obtained from DLS (homogenous size distribution), Zeta potential (higher negative charge), XRD (no other element interference), and SEM-EDS (53 % selenium encapsulation and negligible agglomeration) further strengthened the stability of the generated Lip-SeNPs compared to liposome-free SeNPs. Furthermore, 74.62 % of the SeNP encapsulation efficiency in liposomes was achieved in this study. In addition, dialysis membrane-based drug release profile studies revealed augmented acidic pH-responsive release profiles of Lip-SeNPs, suggesting a superior bioavailability for drug delivery against lung cancer cells.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"7 ","pages":"Article 100121"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143146335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Viscous heating of hybridized hydromagnetic MWCNTs-Fe3O4/water nanomaterial in a moving disk with non-uniform thermal model","authors":"S.O. Salawu ,&nbsp;T.A. Yusuf ,&nbsp;E.O. Fatunmbi ,&nbsp;A.M. Obalalu","doi":"10.1016/j.nxnano.2024.100123","DOIUrl":"10.1016/j.nxnano.2024.100123","url":null,"abstract":"<div><div>The potential usefulness of hybrid nanofluid in biotechnology, medicine, heat exchangers, thermal enhancement, and others is steadily increasing. Meanwhile, the efficiency of nanofluid depends on the based fluid, nanoparticle size and type, and other entrenched dynamical fluid properties. Thus, this research examines the viscous heating of hybridized hydromagnetic MWCNTs-Fe<span><math><msub><mrow></mrow><mrow><mn>3</mn></mrow></msub></math></span>O<span><math><msub><mrow></mrow><mrow><mn>4</mn></mrow></msub></math></span>/water (Multi-walled carbon nanotubes-Iron III oxide/water) of nanofluid in a moving disk with a non-uniform thermal model. For the theoretical analysis, 75% of H<span><math><msub><mrow></mrow><mrow><mn>2</mn></mrow></msub></math></span>O, 20% of Fe<span><math><msub><mrow></mrow><mrow><mn>3</mn></mrow></msub></math></span>O<span><math><msub><mrow></mrow><mrow><mn>4</mn></mrow></msub></math></span> and 5% of MWCNTs are considered with shape factors <span><math><mrow><msub><mrow><mi>n</mi></mrow><mrow><mn>1</mn></mrow></msub><mo>=</mo><msub><mrow><mi>n</mi></mrow><mrow><mn>2</mn></mrow></msub><mo>=</mo><mn>3</mn><mo>.</mo><mn>0</mn></mrow></math></span>. The Fe<span><math><msub><mrow></mrow><mrow><mn>3</mn></mrow></msub></math></span>O<span><math><msub><mrow></mrow><mrow><mn>4</mn></mrow></msub></math></span> and MWCNTs hybridized nanoparticles in water-solvent give a promising approach to augment heat conductivity and magneto-nanofluid properties for advanced thermal distribution systems. A spatial temperature variation of a non-uniform thermal model is assumed to simulate practical phenomena. A similarity transformation of the governing model is done and solved by coupling a numerical shooting technique with a Runge–Kutta scheme. The tabulated and graphically presented results reveal that the thermal propagation rate is improved by 21.34% as 0.25 volume of NWCNTs-Fe<span><math><msub><mrow></mrow><mrow><mn>3</mn></mrow></msub></math></span>O<span><math><msub><mrow></mrow><mrow><mn>4</mn></mrow></msub></math></span> nanoparticle is distributed in 0.5 volume of H<span><math><msub><mrow></mrow><mrow><mn>2</mn></mrow></msub></math></span>O solvent. Hence, the outcomes of this research provide noteworthy insights into the maximization and designing of thermal transport systems contributing to the advancement of thermal management efficiency.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"7 ","pages":"Article 100123"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143146337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"siRNA therapeutics for effective management of rheumatoid arthritis","authors":"Vishakha R. Chakole ,&nbsp;Tathagata Dutta ,&nbsp;Priyankar Sen","doi":"10.1016/j.nxnano.2025.100135","DOIUrl":"10.1016/j.nxnano.2025.100135","url":null,"abstract":"<div><div>siRNA is a specialized type of RNA that precisely targets a mRNA, and effectively silences the respective genes. This property makes siRNA a valuable tool for developing RNAi therapeutics, particularly for managing conditions like osteoporosis, cancer, genetic disorders, and autoimmune disorders. Rheumatoid arthritis (RA) is a significant autoimmune disorder. Several treatments are available for RA, including analgesics, corticosteroids, DMARDs, biological agents, combinational therapy, epigenetic and cell therapies which play a crucial role in preventing joint function deterioration, inflammation, synovial edema, etc. Besides these numerous advantages, these treatments have several disadvantages like liver cirrhosis, interstitial lung disease, sexual health is impaired in males, neuropsychiatric adverse effects, etc. All these disadvantages engender the need for new therapy. siRNA delivery carriers like liposomes, polymeric nanoparticles, and siRNA polymer bio-conjugates are proving to be particularly effective with less toxicity compared to the traditional treatments. A promising addition to these carriers is wrapsome (WS), which can be used as a favorable carrier for delivery of siRNA to its specific sites, such as inflamed joints or the inflamed synovium. The incorporation of PEG liposomes in the delivery strategy allows WS to evade recognition by the RES, leading to an extended half-life. This extended half-life enables a sustained, slow release of the drug, contributing to superior recovery from pain and inflammation associated with conditions like RA.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"7 ","pages":"Article 100135"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143146412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nitrogen-rich dendrimer-like hexamethylenetetramine grafted magnetite nanoreactor as sustainable next-generation materials for catalysis in organic reactions","authors":"Prakash B. Rathod ,&nbsp;K. S. Ajish Kumar ,&nbsp;Kalyan Yakkala ,&nbsp;Mahendra Pratap Singh ,&nbsp;Anjali A. Athawale ,&nbsp;Ashok K. Pandey","doi":"10.1016/j.nxnano.2025.100148","DOIUrl":"10.1016/j.nxnano.2025.100148","url":null,"abstract":"<div><div>The Fe₃O₄@(TEA-HMTA)₂ magnetically retrievable nanoreactor developed in the present work has dendrimer-like branched architecture formed by grafting hexamethylenetetramine (HMTA) onto magnetite (Fe₃O₄) nanoparticles. This structure is synthesized through sequential reactions involving tris(2-bromoethyl)amine and HMTA with n-[3-(trimethoxysilyl)propyl]ethylenediamine-anchored Fe₃O₄ nanoparticles. The resulting nanoreactor offered abundant reactive sites and high nitrogen content in tertiary and quaternary amines, making it suitable for catalyzing the organic syntheses. The magnetic core of the nanoreactor allowed easy recovery, promoting sustainability in catalytic processes. The adaptability of the nanoreactor was demonstrated by its transformation into metallodendrimers (MDs) through selective loading of catalysts such as palladium, copper, or phosphomolybdic acid as representative examples. Its efficacy was validated in several reactions. In the aza-Michael addition, the nanoreactor achieved an 85 % yield with a turnover number (TON) of 21,546 and retained its reusability. The Cu-loaded variant gave a 90 % yield in the nitroaldol reaction with a TON of 4736, while the Pd-loaded system exhibited a 90 % yield in Heck coupling with a TON of 10,222 over four cycles. In ring-opening and phase-transfer reactions, moderate yields of 60 % and 55 % were achieved, with TONs of 789 and 6971, respectively. The magnetic nanoreactors exhibited the possibility of loading homogeneous catalysts with remarkable catalytic efficacy.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"8 ","pages":"Article 100148"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143551424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Green and facile synthesis of silver nanoparticles (Ag NPs) using Rhamnus prinoides (Gesho) leaf extract for antibacterial, antioxidant and photocatalytic activities","authors":"Bekalu Lake Bogale ,&nbsp;Teshiwal Bizuayen Adamu ,&nbsp;Mekuriaw Assefa kebede ,&nbsp;Misganaw Tegegne Ayana ,&nbsp;Wudu Wale Kebede ,&nbsp;Tsehaynew Fetene","doi":"10.1016/j.nxnano.2025.100163","DOIUrl":"10.1016/j.nxnano.2025.100163","url":null,"abstract":"<div><div>The current work describes a simple and environmentally friendly method of creating silver nanoparticles (AgNPs) by employing leaf extract from Rhamnus prinoides (Gesho) as a capping and reducing agent. This environmentally friendly process provides a sustainable substitute for biological synthesis method. By adjusting the AgNO₃ concentration, extract-to-silver nitrate ratio, pH, and incubation duration, the biosynthesis conditions were adjusted. UV-Vis spectroscopy (λ_max = 407 nm) verified the production of AgNPs, while FTIR analysis revealed the functional groups in charge of stabilization and reduction. SEM photos displayed a uniform spherical shape, TGA proved their thermal stability up to 680°C, and XRD examination showed a face-centered cubic crystalline structure with an average particle size of 9.45 nm. The synthesized AgNPs exhibited significant antibacterial activity against Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus, and Streptococcus pyogenes, outperforming the plant extract alone. Additionally, the AgNPs demonstrated strong antioxidant potential in a DPPH assay, with an IC₅₀ value of 48.85 μg/mL and excellent photocatalytic degradation of malachite green dye (95 % efficiency under visible light for 100 min). These results suggest that AgNPs synthesized using Rhamnus prinoides leaf extract have potential applications in antibacterial, antioxidant, and photocatalytic activities, making them promising candidates for biomedical and environmental applications.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"7 ","pages":"Article 100163"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143776816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding the synthesis mechanism of arginine functionalized silver/silver chloride nanoparticles using sugar ligands","authors":"Şuheda Bolat ,&nbsp;Suna Değirmenci ,&nbsp;Abdurrahman Gümüş ,&nbsp;Zafer Sancak ,&nbsp;İdris Yazgan","doi":"10.1016/j.nxnano.2025.100160","DOIUrl":"10.1016/j.nxnano.2025.100160","url":null,"abstract":"<div><div>In this study, we performed a mechanistic study to understand how the sugar ligand chemistry affected the morphology, size and surface chemistry of Ag/AgCl_NPs synthesized in the presence of L-Arginine hydrochloride and L-Arginine/KCl mixture. The sugar ligands Lactose <em>p</em>-methoxyaniline (LMA) and Galactose 5-aminosalicylic acid (G5AS) resulted in formation of sheet-like Ag/AgCl_NPs while Lactose sulfanilic acid (LSA) and Lactose <em>p</em>-sulfonyldianiline (LPSA) caused the formation of anisotropic and film-like Ag/AgCl_NPs. The UV-Vis based mechanistic studies showed that the presence of Arginine posed a strong effect on how G5AS and LMA ligands interact with silver ions while the effect was more complicated for the LSA and LPSA ligands due to the fact that they form complexation with Ag⁺ ions. The mechanism was further investigated using infrared (IR) studies that showed the increases in Argine and chloride ion concentrations resulted in differentiation of the surface chemistry of the Ag/AgCl_NPs, and appearance of Arginine related IR bands became clearer in the case of co-introduction of Arginine and the sugar ligands. The characterized nanoparticles were then used as antibacterial agent for multidrug resistant <em>Escherichia coli</em> species for which less than 10 µM minimum inhibitory concentrations were obtained. The promising antibacterial activity, which could be assigned to the presence of Arginine, was independent from the sugar ligand chemistry and nanoparticles’ morphology and size. Particularly, large Ag/AgCl_NP film forming capacity can call further research to be exploited as coating materials for antibacterial application.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"7 ","pages":"Article 100160"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143768041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel green synthesis of silver nanoparticles from empty fruit bunch waste: Biomedical applications and mechanistic insights","authors":"Bashirat Olamide Yusuf-Salihu ,&nbsp;Shakirat Afodun Abdulmumini ,&nbsp;Toheeb Taiye Bajepade ,&nbsp;Halimah Adekunbi Durosinmi ,&nbsp;Muinat Olanike Kazeem ,&nbsp;Victoria Atinuke Ajayi ,&nbsp;Agbaje Lateef","doi":"10.1016/j.nxnano.2025.100136","DOIUrl":"10.1016/j.nxnano.2025.100136","url":null,"abstract":"<div><div>Agricultural waste, such as empty fruit bunches (EFB) from palm oil production, poses environmental and health risks if not effectively managed. This study addresses this issue by innovatively transforming EFB biomass into high-value silver nanoparticles (AgNPs) via a green synthesis approach, marking the first successful biosynthesis of AgNPs from EFB. UV-Vis, FTIR, TEM, SAED, and EDX studies were used to characterize biosynthesized EFB-AgNPs. Biosynthesized EFB-AgNPs were tested for antibacterial, antioxidant, antidiabetic, anticoagulant, and thrombolytic activities. EFB-AgNPs showed a surface plasmon resonance peak at 477 nm, hydroxyl and amine group stabilization, and a silver content of 75.56 %. TEM and SAED analyses confirmed nanoscale particle diameters ranging from 12.78 nm to 19.10 nm, with a characteristic face-centered cubic (FCC) crystalline structure. EFB-AgNPs inhibited <em>Escherichia coli</em>, <em>Klebsiella oxytoca, Staphylococcus aureus</em>, <em>Proteus mirabilis</em>, and <em>Pseudomonas aeruginosa</em> dose-dependently from 40 % to 80 %, and 100 % of <em>Aspergillus niger</em>, <em>A. fumigatus,</em> and <em>A. flavus</em>. Reactive oxygen species (ROS) may cause cell membrane rupture and oxidative stress. Antioxidant testing demonstrated concentration-dependent activity across multiple assays: DPPH scavenging reached 81.49 % at 160 µg/ml, ferric-reducing activity was 90.05 % at 150 µg/ml, H₂O₂ scavenging achieved 91.00 % at 80 µg/ml, and NO scavenging reached 83.43 % at 150 µg/ml. Furthermore, EFB-AgNPs prevented blood coagulation and dissolved blood clots. In addition, EFB-AgNPs inhibited α-amylase with 74.64 % at 100 µg/ml. This unique approach of transforming EFB trash into high-value AgNPs could help sustain waste management and the circular bioeconomy by enabling medicinal applications.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"7 ","pages":"Article 100136"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143146340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"OLED-on-silicon (OLEDoS) microdisplays: Technology challenges, design considerations, and adaptation in eXtended Reality (XR) ecosystem – Review","authors":"Rifat Kaçar ,&nbsp;Ramis Berkay Seri̇n ,&nbsp;Esin Uçar ,&nbsp;Murat Artuç ,&nbsp;Alper Ülkü ,&nbsp;Barış Kınacı","doi":"10.1016/j.nxnano.2025.100132","DOIUrl":"10.1016/j.nxnano.2025.100132","url":null,"abstract":"<div><div>Microdisplay technologies include a variety of miniature display solutions designed to specific requirements in various applications, such as near-to-eye (NTE) platforms. Among these solutions, OLED based microdisplays stands out as an advanced micro-display technology that goes beyond the core principles of conventional OLED technology. This review investigates deeply into the landscape of OLED-on-Silicon (OLEDoS) microdisplays, providing a meticulous analysis of both the CMOS backplane and the OLED frontplane technology, along with subsidiary technologies. It thoroughly examines the challenges and potential drawbacks associated with each technology, offering a comprehensive understanding of their limitations. It also sheds light on the advancements and breakthroughs in the field and highlights the design considerations to overcome the outlined limitations. OLEDs are ideal for microdisplays due to their high contrast ratios, deep blacks, and fast response times, all essential for eXtended Reality (XR) experiences. Their self-emissive nature, which eliminates the need for backlighting, enabling thin, light, power-efficient displays with vibrant colors. These features make OLEDoS microdisplays particularly well-suited for NTE platforms. The review also examines the commercial landscape of OLEDoS, covering market trends, major industry players, and the adoption of these technologies across the industry. In conclusion, it provides a forward-looking perspective on the future of OLEDoS microdisplays, outlining emerging trends and opportunities within the rapidly evolving XR ecosystem.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"7 ","pages":"Article 100132"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143146411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrating advanced synthesis techniques and AI-driven approaches with nanofiber technology: A state-of-the-art approach to wound care management","authors":"Nisha Shankhwar ,&nbsp;Awadhesh Kumar Verma ,&nbsp;Ashab Noumani ,&nbsp;Tanya Singh ,&nbsp;Kalakuntla Sriharshitha Rao ,&nbsp;Vivekanand ,&nbsp;Neeta Raj Sharma ,&nbsp;Satyendra Singh","doi":"10.1016/j.nxnano.2025.100147","DOIUrl":"10.1016/j.nxnano.2025.100147","url":null,"abstract":"<div><div>Wound healing is a complicated clinical problem when common topical therapies and dressings are insufficient for different kinds of wounds, such as burns, surgical, and chronic wounds. This review emphasizes the ground-breaking potential of nanofiber technology, a novel approach that imitates the extracellular matrix (ECM) to promote targeted therapeutic administration and support cellular regeneration. Because of their structural compatibility with skin tissue, nanofiber dressings enhance natural healing, maintain optimal moisture levels, and significantly reduce the risk of infection. The comprehensive analysis include methods for producing nanofibers, crucial design components, and applications appropriate for different wound types. Concurrently, the integration of the Internet of Things (IoT), Artificial Intelligence (AI), and Machine Learning (ML) is revolutionizing wound care. Because of this, \"smart\" dressings with real-time monitoring, dynamic data processing, and precise therapeutic release capabilities have been developed, allowing medical personnel to provide more individualized and responsive care. These developments can potentially revolutionize wound care through timely interventions and improving patient outcomes. Although combining nanofiber technology with AI-powered smart dressings seems promising, there are still barriers in implementing these developments for general clinical applications. This review offers a comprehensive overview of current research and the critical role nanofiber technology plays in enhancing wound care. We plan to highlight the path for robust, scalable, and customized wound treatments by identifying key implementation barriers and exploring potential developments. Nanofibers, with their exceptional capabilities, signify a profound advancement in wound healing, offering new optimism for improved patient recovery and enduring health benefits.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"8 ","pages":"Article 100147"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143551421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}