Next Nanotechnology最新文献

{"title":"Graphite-based nanocomposite for advancement of wastewater treatment: A comprehensive review","authors":"Ravikumara Moodalakoppalu Yogarajachari ,&nbsp;Shankramma Kalikeri","doi":"10.1016/j.nxnano.2026.100390","DOIUrl":"10.1016/j.nxnano.2026.100390","url":null,"abstract":"<div><div>Advanced and effective wastewater treatment technologies have become increasingly important in recent years due to growing global concern about water pollution. This review aims to explore the potential of graphite-based nanocomposites as a novel platform for advancing wastewater treatment, drawing on recent research from around the world. Graphite-based nanocomposites leverage the unique properties of graphite to enhance adsorption, catalysis, and separation processes, thereby enabling the removal/degradation of various pollutants from wastewater. The synthesis, characterization, and performance evaluations of these nanocomposites against various pollutants are elaborately discussed. The key findings reveal their superior performance in addressing water pollution problems. Their application in real scenarios has promising prospects in developing sustainable and environmentally friendly wastewater treatment technologies.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"9 ","pages":"Article 100390"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146187993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antimicrobials from nano sulfur: Innovations, applications, and future perspectives","authors":"Moumita Sil ,&nbsp;Ankita Dey ,&nbsp;Mita Rani Chanda ,&nbsp;Rakesh Ghosh ,&nbsp;Arunava Goswami ,&nbsp;Shauryabrota Dalui ,&nbsp;Debasmita Bhattacharya ,&nbsp;Moupriya Nag ,&nbsp;Dibyajit Lahiri","doi":"10.1016/j.nxnano.2026.100382","DOIUrl":"10.1016/j.nxnano.2026.100382","url":null,"abstract":"<div><div>The sudden worldwide spread of multidrug-resistant (MDR) Gram-negative bacilli (GNB), particularly carbapenemase producers such as New Delhi metallo-β-lactamase-1 (NDM-1), is an emerging, clinically and public health-relevant challenge. The antibiotics, including carbapenems, become progressively less effective, making it necessary to develop alternative therapeutic options. Nanotechnology opens new avenues, including unique physicochemical properties of nanomaterials at the nanoscale. Sulfur, which has long been recognized for its antimicrobial activity, proves to be more effective when engineered as sulfur nanoparticles (S-NPs). This review emphasizes the antibacterial promise of PEG-stabilized S-NPs against MDR pathogens. PEGylation enhances the stability, dispersibility, and bioavailability of nanoparticles, leading to enhanced antimicrobial efficacy and decreased cytotoxicity in comparison to unaltered S-NPs. Mechanistic investigations indicate that S-NPs affect microbes through reactive oxygen species production, membrane disruption in bacteria, inhibition of metabolic processes, and probable interactions with resistance determinants like NDM-1. Comparative studies demonstrate that PEG-S-NPs have lower minimum inhibitory concentrations than their larger, uncoated counterparts, highlighting the influence of surface engineering on antimicrobial activity. Moreover, synergies with last-line antibiotics such as colistin and tigecycline highlight their potential for combination therapy. <em>In vitro</em> and <em>in vivo</em> evidence validating their broad-spectrum effectiveness and acceptable safety profiles has created challenges in large-scale production, long-term biocompatibility, ecological safety, and translation to regulatory approval. Future studies would emphasize standardized comparison studies, mechanistic explanation, and preclinical assessment to facilitate clinical use. PEGylated S-NPs are a promising next-generation antimicrobial approach that can revolutionize the treatment of MDR infections and solve one of the most important global health issues.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"9 ","pages":"Article 100382"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146188012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Photocatalytic degradation phenomena of methylene blue dye by ZnFe2O4 decorated with rGO nanocomposites under visible light irradiation","authors":"Hina Anjum Kouser ,&nbsp;E. Vinay Kumar ,&nbsp;Vinuta Kamat ,&nbsp;H.S. Bhojya Naik","doi":"10.1016/j.nxnano.2025.100342","DOIUrl":"10.1016/j.nxnano.2025.100342","url":null,"abstract":"<div><div>Recent advancements in photocatalytic technologies have opened sustainable pathways for the removal of organic pollutants from wastewater. In the present study, a reduced graphene oxide (rGO)-modified ZnFe₂O₄ (rGO-ZFO) nanocomposite was successfully synthesized using a simple solution combustion method to improve charge separation efficiency and enhance visible-light-driven photocatalytic activity. The synthesized materials were characterized by XRD, FTIR, SEM, TEM, UV-Vis, and PL analyses, which confirmed the successful incorporation of rGO into the ZnFe₂O₄ matrix. The modification led to enhanced crystallinity, suppression of charge carrier recombination, and a reduction in band gap energy. These improvements significantly contributed to the superior photocatalytic performance of the rGO-ZFO composite, achieving 93 % degradation of methylene blue under visible light within 180 min. Furthermore, scavenger experiments identified the major reactive species involved in the degradation pathway, providing deeper insight into the underlying mechanism. This study establishes a clear structure-property-performance correlation and highlights that rGO incorporation effectively optimizes the electronic and surface characteristics of ZnFe₂O₄, rendering it a promising, eco-friendly, and efficient photocatalyst for wastewater treatment applications.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"9 ","pages":"Article 100342"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145750146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterization of cadmium-doped nZVI residuals: Structure, morphology, and photoelectrochemical properties","authors":"Camila Morales-Navas ,&nbsp;Annelis O. Sánchez-Álvarez ,&nbsp;Joesene J. Soto-Pérez ,&nbsp;Eduardo Larios ,&nbsp;Arnulfo Rojas ,&nbsp;Carlos R. Cabrera","doi":"10.1016/j.nxnano.2025.100327","DOIUrl":"10.1016/j.nxnano.2025.100327","url":null,"abstract":"<div><div>This study explores a novel approach to reuse the residual material generated after environmental remediation processes using nanoscale zero-valent iron (nZVI) nanoparticles. While nZVI has been evaluated for the removal of heavy metal ions in contaminated areas, it has yet to provide a definitive solution. We propose utilizing the residual nZVI material for photo-harvesting in photoelectrochemical cells. Here, we report on the material's transformation into a Fe⁰/Fe_xO_y Cd_1−xFe_xO_y catalyst and investigate its potential through X-ray photoelectron spectroscopy (XPS), inductively coupled plasma (ICP), transmission electron microscopy (TEM), and X-ray diffraction (XRD). On the other hand, traditional characterization methods were also employed to validate the versatility of the Cathodic Particle Coulometry (CPC) technique. This method is especially sensitive to conductive and semiconductive particles, such as metal oxides or corrosion products, as they generate distinct current signals when reduced or oxidized under cathodic conditions. CPC permits the sizing of the particle, and the obtained results are discussed hereinafter. Interestingly, a staircase response was also obtained for the most concentrated sample of particles suggesting a blocking mechanism. The inclusion of cadmium (Cd) in the nZVI residual material resulted in structural changes, shifting from a hexagonal hematite lattice to a face-centered cubic CdFe₂O₄ phase. Incident photon-to-current efficiency measurements revealed a 10-fold increase in efficiency compared to the original nZVI material. Furthermore, photovoltage measurements as a function of Cd content suggest that Cd alters the semiconductor properties of the Fe_xO_y structure. This study highlights the potential of cadmium-doped iron residual materials (Cd-IR) in enhancing the performance of photoelectrochemical solar cells (PSC) and provides insights into the changes in material properties and structure due to Cd incorporation.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"9 ","pages":"Article 100327"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145694760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Green biosynthesis of silver nanoparticles from Citrus aurantium leaves plant as corrosion inhibitor for carbon steel in sulfuric acid","authors":"Noor H. Kurshed ,&nbsp;Anees A. Khadom ,&nbsp;Rusul K. Ismail ,&nbsp;Saja Khalil Mohuee ,&nbsp;Noor Kadhim Ahmed ,&nbsp;A. Alamiery","doi":"10.1016/j.nxnano.2025.100331","DOIUrl":"10.1016/j.nxnano.2025.100331","url":null,"abstract":"<div><div>Citrus aurantium leaves (CAL) and silver nanoparticles (AgNPs) were used in the biosynthesis of a corrosion inhibitor for low-carbon steel in 0.5 M H₂SO₄. The weight loss method was used to investigate the corrosion inhibition performance of the composite (CAL-AgNPs). It was found that the corrosion rate of low-carbon steel increased with temperature increase and decreased with CAL-AgNPs concentration increase. Maximum corrosion inhibition efficiency was 91.3 % at 10 ml/l and 30°C. Adsorption studies indicated that CAL-AgNPs can be adsorbed spontaneously on the metal surface. The adsorption mechanism was primarily physical and followed the Langmuir adsorption isotherm. The kinetics studies confirmed these outcomes, showing a higher activation energy in the presence of CAL-AgNPs compared to the blank solution. This indicated the formation of a protective layer on the metal surface that increased the energy barrier. The FTIR technique was used as a direct method of CAL functional group diagnosis and an indirect one for AgNPs presence. The FTIR spectra showed the stretching for functional groups like alcohols, phenols, N–H of amines, C–H stretching, esters, aldehydes, and carboxylic acids, which are common in capping biomolecules. In addition, spectra in the range of metal-O bonds, such as Ag–O or Ag–N, were observed.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"9 ","pages":"Article 100331"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145694947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nanotechnology for Sustainable Waste Management and Ecosystem Restoration: Applications, Innovations, Ecosystem Services and Disservices, and Contributions to the UN Sustainable Development Goals","authors":"Govindaraj Kamalam Dinesh,&nbsp;Sangilidurai Karthika,&nbsp;R. Abhinayaa,&nbsp;R. Prasannadevi,&nbsp;Murugaiyan Sinduja,&nbsp;Sathya Velusamy,&nbsp;A.S. Goveanthan,&nbsp;D. Pradeep,&nbsp;Shiv Prasad,&nbsp;Cherukkumalli Srinivasarao,&nbsp;Panneerselvam Sivasakthivelan,&nbsp;Nanthi Bolan,&nbsp;Veluswamy Venkatramanan,&nbsp;Rachana Dubey,&nbsp;Somasundaram Jayaraman,&nbsp;Prakash Kumar Sarangi,&nbsp;Punabati Heisnam,&nbsp;Chandrasekaran Nivaethaa","doi":"10.1016/j.nxnano.2026.100507","DOIUrl":"10.1016/j.nxnano.2026.100507","url":null,"abstract":"<div><div>Around the world, the human population is increasing rapidly, and demand for essential commodities and finished products is rising daily. Their uncontrolled usage of consumer goods generates considerable waste, ultimately impacting the global environment and the sustainability of natural resources. Nanotechnology has emerged as a versatile platform capable of delivering efficient, effective, economical, and eco-friendly solutions for green waste management. Current thematic research trends in material science highlight the growing application of engineered nanomaterials, including nanocomposites and functionalized nanoparticles, as high-performance sustainable adsorbents for targeted pollutant removal. Advances in Nano Engineering further demonstrate the precision fabrication of nano-catalysts and nano-enabled remediation systems for scalable ecosystem restoration. This is because nanomaterials with high surface-to-volume ratios can efficiently absorb and remediate pollutants, helping restore polluted ecosystems. In addition, nanomaterials can catalyze the conversion of toxic gases, heavy metals, and many other inorganic and organic contaminants into non-hazardous substances. Nanotechnology is one of the most promising technologies for recycling and managing waste. Nanotechnology has the potential to provide a range of ecosystem services. It addresses several of the UN's Sustainable Development Goals (SDGs), including Goals 3 (Good Health and Well-being), 6 (Clean Water and Sanitation), 7 (Affordable and Clean Energy), 9 (Industry, Innovation and Infrastructure), and 13 (Climate Action). These goals are all related to improving people's lives and protecting the planet, which are key aims of the UN's 2030 Agenda for Sustainable Development. This review provides an overview of nanotechnology applications in waste management and ecosystem restoration. Additionally, it examines the perspectives on future challenges. It provides technical details on how nanotechnology helps resolve various environmental issues.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"9 ","pages":"Article 100507"},"PeriodicalIF":3.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148523672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Convergence of molecular biology and nanobiotechnology: Advances in precision therapeutics and next-generation diagnostics","authors":"Abang Ulrich Akwo,&nbsp;Ketonze Valademy Ketu,&nbsp;Ayang Blessing Enjong,&nbsp;Lamivine Asibe Akam,&nbsp;Chah Gabriel Aleisahmbom,&nbsp;Irrinus Fonyuy Kintung,&nbsp;Mekue Kamdem Grace,&nbsp;Tiomela Tikeng Vanelle","doi":"10.1016/j.nxnano.2026.100493","DOIUrl":"10.1016/j.nxnano.2026.100493","url":null,"abstract":"<div><div>The combination of molecular biology and nanobiotechnology has spurred a paradigm shift in precision medicine, offering unparalleled capabilities in disease detection, targeted therapy, and tissue regeneration. This thorough study investigates the synergistic integration of different disciplines, concentrating on molecular design concepts that inform the creation of nanoscale platforms for therapeutic and diagnostic applications. We thoroughly study core molecular biology concepts, including nucleic acid biochemistry, protein interactions, and gene regulation, which provide critical blueprints for constructing intelligent nanocarriers. The review categorises and evaluates different nanomaterials (inorganic nanoparticles, organic carriers, and hybrid systems) and their modes of action, highlighting targeted administration tactics, stimulus-responsive systems, and theragnostic approaches. We objectively analyse translational applications across important disease domains: oncology, neurological disorders, cardiovascular illnesses, wound healing, and antibiotic resistance. Emerging frontiers, including CRISPR-Cas systems, artificial intelligence, organ-on-a-chip platforms, and bioelectronic interfaces, are highlighted as revolutionary directions. Despite tremendous advances, issues in scalability, regulatory harmonisation, and equal access persist. This study synthesises recent advances while proposing a path for future research, stressing interdisciplinary collaboration and clinical translation. The merging of molecular biology with nanoscale engineering holds transformative potential for personalised, predictive, and precision healthcare solutions that address 21st-century medical concerns.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"9 ","pages":"Article 100493"},"PeriodicalIF":3.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148523675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Root-applied graphene oxide, nano-Fe3O4, and GO/Fe3O4: Role in mitigating arsenic and cadmium mixed toxicity in ryegrass (Lolium perenne L.)","authors":"Wenwen Li ,&nbsp;Yi Zhang ,&nbsp;Haobing Xiong ,&nbsp;Dini Dai ,&nbsp;Jianchun Xie ,&nbsp;Wenbin Yang","doi":"10.1016/j.nxnano.2025.100337","DOIUrl":"10.1016/j.nxnano.2025.100337","url":null,"abstract":"<div><div>Iron oxides profoundly have a significant impact on biogeochemical cycles of both arsenic (As) and cadmium (Cd), especially in terms of plant uptake. Few-layer graphene, which closely coexists with iron oxides in lunar soil, may also serve as a model for understanding future Earth environment. Therefore, research on the combined effect of graphene oxide (GO) and nano-Fe₃O₄ on the uptake of mixed As and Cd (As/Cd) by plant is urgent needed. In this study, GO, nano-Fe₃O₄, and their composite (GO/Fe₃O₄) were applied to hydroponic <em>Lolium perenne</em> L. (ryegrass), with both metals at the same concentration of 10 mg·L⁻¹. The aim was to clarify the roles of each material. The results showed that GO significantly increased phosphorus (P) content in the shoots of ryegrass, boosting it by 1.32 folds. It also preserved the structure of the root tip tissue and enhanced antioxidant enzyme activities in the shoots. On the other hand, nano-Fe₃O₄ increased Fe content in the roots by 1.14 folds, reduced the bioaccumulation of As and Cd, and promoted rapid electron transfer. Genes expression analysis revealed that GO/Fe₃O₄ composite upregulated glutathione reserves while downregulating the proline synthesis pathway. The upregulation of the LpYSL6 transporter suggested that GO/Fe₃O₄ facilitated the fixation of As and Cd in the roots of ryegrass in chelated forms. This investigation highlights the potential of GO/Fe₃O₄ as an effective nanomaterial for mitigating plant stressed caused by mixed toxic metals, supporting sustainable agricultural practices.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"9 ","pages":"Article 100337"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145799878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biogenic, facile, and sustainable pathway of obtaining ZnO-PS nanoparticles through Pisum sativum waste peels, their characterization and cytotoxic assessment against HeLa cell line via experimental and computational methods","authors":"Mehar Rizvi ,&nbsp;Renu Gupta ,&nbsp;Saurabh Kumar ,&nbsp;Monisha Banerjee","doi":"10.1016/j.nxnano.2025.100322","DOIUrl":"10.1016/j.nxnano.2025.100322","url":null,"abstract":"<div><div>The effectiveness of cancer treatment is hindered by the side effects of chemotherapy, drug resistance, and the spread of tumor. Therefore, necessitating alternative treatment methods. Nanotechnology holds promise for the future of cancer treatment. The present study utilizes an aqueous extract derived from <em>Pisum sativum</em> (green peas) waste peels to synthesize ZnO nanoparticles (ZnO-PS NPs) and investigate their novel anticancer activity against HeLa cervical cancer cells <em>in vitro</em> via a straightforward, affordable, environmentally friendly, and non-toxic biogenic route. X-ray diffraction (XRD) analysis confirmed the formation of ZnO-PS NPs with an average crystallite size of 22.63 nm, exhibiting a hexagonal (wurtzite) structure. TEM results revealed an average particle size of 18.064 nm. The UV-Vis spectrum displayed a prominent peak at 370 nm and an energy band gap of 3.35 eV. The FT-IR spectroscopy identified the surface biomolecules. Cytotoxicity experiments conducted using the MTT method demonstrated a significant inhibitory effect of ZnO-PS NPs against HeLa cells, with an IC₅₀ value of 55 ± 1.27 μM. Furthermore, docking studies were performed on cancer-related proteins (Crm1, HPV oncoprotein E-6, Transketolase, BRAF, and NF-kappa proteins) involved in cancer cell survival and proliferation.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"9 ","pages":"Article 100322"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145799877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ligands tuned Zn-MOFs with superior electrocatalytic performance for BPA sensor construction","authors":"Md Maruf Ahmed ,&nbsp;Xiang Jiahong ,&nbsp;Zheng Wang ,&nbsp;Zheng Zhang ,&nbsp;Yingzhuo Shen ,&nbsp;Seytkhan Azat ,&nbsp;Qin Xu","doi":"10.1016/j.nxnano.2025.100357","DOIUrl":"10.1016/j.nxnano.2025.100357","url":null,"abstract":"<div><div>The design and tuning of metal–organic frameworks (MOFs) have emerged as a powerful strategy for designing advanced sensors that enable accurate and rapid analyte detection. In this study, the effect of several organic linkers (1,4-benzene dicarboxylic acid, benzene-1,3,5-tricarboxylate acid, biphenyl-4,4′-dicarboxylate acid, and 1,3,5-Tris(4-carboxyphenyl) benzene) on the morphological and structural properties of Zn-MOFs has been studied. Additionally, the as-prepared Zn-MOFs were utilized to investigate their BPA sensing properties. Ligand tuning enhances sensor performance by introducing functional groups that promote stronger analyte interactions and faster signal response. The Zn-BPDC (biphenyl-4,4′-dicarboxylate) promotes robust π-π stacking interactions between the aromatic rings of BPA and the BPDC ligands, thereby increasing sensing capabilities. Furthermore, it promotes the formation of a needle-shaped structure, which has superior BPA sensing capabilities compared to other Zn-MOFs. The current response of the Zn-BPDC/GCE exhibited a robust linear correlation with BPA concentrations from 0.05 to 6 μM and a low detection limit of 0.033 μM with excellent stability. The practical applicability of the sensor was evaluated using milk, drinking water, and tap water, achieving impressive recovery of BPA between 94.1 % and 105.6 %. Thus, the designed sensor may serve as a viable alternative for the identification of BPA as well as estrogenic substrates.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"9 ","pages":"Article 100357"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145799938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}