Next Nanotechnology最新文献_第5页

ZnO/CdS nanocomposites: Synthesis, characterization and assessment of photocatalytic performance ZnO/CdS纳米复合材料的合成、表征及光催化性能评价

Next Nanotechnology Pub Date : 2025-01-01 DOI: 10.1016/j.nxnano.2025.100146

Anupam Sarker , Shahriar Atik Fahim , Rupna Akther Putul , Humayra Gazi , Shah Md. Masum , Md. Ashraful Islam Molla

{"title":"ZnO/CdS nanocomposites: Synthesis, characterization and assessment of photocatalytic performance","authors":"Anupam Sarker , Shahriar Atik Fahim , Rupna Akther Putul , Humayra Gazi , Shah Md. Masum , Md. Ashraful Islam Molla","doi":"10.1016/j.nxnano.2025.100146","DOIUrl":"10.1016/j.nxnano.2025.100146","url":null,"abstract":"<div><div>This study investigates the photocatalytic degradation of Methyl orange (MO) dye using ZnO/CdS nanocomposites synthesized by the hydrothermal technique. Using XRD, FTIR, FESEM-EDS, TEM, UV-Vis DRS, BET, and XPS, the chemically produced chalcogenide hybrid nanocomposites were thoroughly characterized. The 5 % ZnO/CdS nanocomposite photocatalyst exhibited a crystallite size of 5.63 nm, a bandgap energy of 2.35 eV, and a larger surface area of 118.47 m<sup>2</sup>/g, indicating excellent photocatalytic performance compared to pristine ZnO and CdS. The best MO removal efficiency of 98.67 % within 60 min is demonstrated by the 5 % ZnO/CdS photocatalyst under UV-C irradiation. The photocatalytic MO degradation reaction maintains a pseudo-first-order kinetic law. The rate constant (<em>k</em>) and half-life (<em>t</em><sub>1/2</sub>) are found to be 0.065 min<sup>−1</sup> and 10.66 min, respectively. The reusability of the 5 % ZnO/CdS photocatalyst was investigated, and the MO removal efficiency remained acceptable after three cycles. These findings suggest that the synthesized ZnO/CdS nanocomposite is a promising photocatalyst for efficiently and sustainably removing organic pollutants from wastewater.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"8 ","pages":"Article 100146"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143551422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Properties of natural hydroxyapatite prepared by pressureless sintering using different temperatures and holding times 不同温度和保温时间下无压烧结制备的天然羟基磷灰石的性质

Next Nanotechnology Pub Date : 2025-01-01 DOI: 10.1016/j.nxnano.2025.100168

Nuradeen Idris , Bashar Dan-Asabe , Semiyou A. Osseni , Kazeem O. Rabiu , Adetunji R. Sowunmi , Naresh D. Bansod , Frantisek Lukac , Stefan Csaki , David O. Obada

{"title":"Properties of natural hydroxyapatite prepared by pressureless sintering using different temperatures and holding times","authors":"Nuradeen Idris , Bashar Dan-Asabe , Semiyou A. Osseni , Kazeem O. Rabiu , Adetunji R. Sowunmi , Naresh D. Bansod , Frantisek Lukac , Stefan Csaki , David O. Obada","doi":"10.1016/j.nxnano.2025.100168","DOIUrl":"10.1016/j.nxnano.2025.100168","url":null,"abstract":"<div><div>The sintering behavior of hydroxyapatite (HAp) particles prepared via pressureless sintering was investigated. The powders were subjected to different sintering temperatures of 900°C and 1000°C for 2, 4, and 6 hours (hr). The sintered HAp powders were analyzed for phase stability, density, Vickers hardness, fracture toughness, brittleness index, and in vitro biological properties. XRD analysis indicated HAp as the dominant phase in all samples. Rietveld refinement quantified the weight percent (wt.%) of HAp to be equal to or more than 97 % in all samples. Scanning electron microscopy (SEM) analyses revealed larger and flattened particle shapes for HAp sintered at 1000°C and this influenced the mechanical properties of the samples. The density of the HAp samples was close to the theoretical density of HAp. Samples sintered with 4-hr holding times displayed greater stability in physiological fluids. In vitro degradation tests in phosphate buffer saline (PBS) under physiological conditions revealed minimal weight loss and stable pH levels over 14 days. This indicates the scaffolds’ potential for long-term physiological stability. Overall, samples sintered at 900°C may be further investigated to enhance their significance in biomedical applications.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"7 ","pages":"Article 100168"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143854821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Photoelectrochemical CO2 reduction on CuO-Cu2O nanocomposites with noble metal co-catalysts enhances the production of C1 oxygenates and acetate 贵金属共催化剂在CuO-Cu2O纳米复合材料上的光电还原CO2提高了C1氧合物和乙酸酯的产量

Next Nanotechnology Pub Date : 2025-01-01 DOI: 10.1016/j.nxnano.2024.100125

Tahereh Mokary Yazdely, Ricard Garcia-Valls, Alberto Puga

{"title":"Photoelectrochemical CO2 reduction on CuO-Cu2O nanocomposites with noble metal co-catalysts enhances the production of C1 oxygenates and acetate","authors":"Tahereh Mokary Yazdely, Ricard Garcia-Valls, Alberto Puga","doi":"10.1016/j.nxnano.2024.100125","DOIUrl":"10.1016/j.nxnano.2024.100125","url":null,"abstract":"<div><div>Multi-junction copper oxide nanocomposite photocathodes formed by CuO nanowire arrays coated with Cu<sub>2</sub>O nanopyramids or stacked nanoprisms, <em>i.e.</em> CuO(NWA)|Cu<sub>2</sub>O(NPy), exhibit remarkable electrochemical stability toward reductive corrosion. Whilst bare CuO nanowires are extremely prone to decomposition even at the mildest potentials applied, the core@shell morphology of CuO(NWA)|Cu<sub>2</sub>O(NPy) resists cathodic potentials up to −0.7 V (<em>vs</em>. AgCl/Ag). Precisely controlled electrodeposition of silver or gold nanoparticles resulted in Ag nanotrails arranged on flatter surface regions in CuO(NWA)|Cu<sub>2</sub>O(NPy)|Ag, whereas Au nanoaggregates were deposited on both flat areas and prominent apexes in CuO(NWA)|Cu<sub>2</sub>O(NPy)|Au. Photocurrent measurements demonstrated redox process activation, namely above three-fold current density increases, by light for CuO(NWA)|Cu<sub>2</sub>O(NPy). The participation of CO<sub>2</sub> in them was also confirmed by around 70 % photocurrent increases (higher than 0.2 mA cm<sup>−2</sup>) and by sensibly milder cathodic potential onsets (≤ −0.4 V), as recorded by linear sweep voltammetry. Photoelectrochemical CO<sub>2</sub> reduction experiments under simulated sunlight yielded oxygenated products in the liquid phase, chiefly formate, although acetate was also consistently produced, especially in the presence of noble metal co-catalysts. Specifically, acetate yields increased by 30–40 % for CuO(NWA)|Cu<sub>2</sub>O(NPy)|Ag and CuO(NWA)|Cu<sub>2</sub>O(NPy)|Au up to 56 and 54 μM, respectively. Methanol could be also formed under specific conditions. A mechanistic proposal is postulated to account for all stability and selectivity phenomena observed.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"7 ","pages":"Article 100125"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143146333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of micellar media on the bioavailability, solubility, and stability of curcumin 胶束介质对姜黄素生物利用度、溶解度和稳定性的影响

Next Nanotechnology Pub Date : 2025-01-01 DOI: 10.1016/j.nxnano.2024.100124

Jamsheera Anjudikkal , Alok Shukla , Ajmal Koya Pulikkal

{"title":"Effects of micellar media on the bioavailability, solubility, and stability of curcumin","authors":"Jamsheera Anjudikkal , Alok Shukla , Ajmal Koya Pulikkal","doi":"10.1016/j.nxnano.2024.100124","DOIUrl":"10.1016/j.nxnano.2024.100124","url":null,"abstract":"<div><div>Curcumin (CUR), a polyphenolic pigment of turmeric, -possess biological and medicinal properties. Regardless of having a wide range of therapeutic applications, CUR’s poor bioavailability, owing to its meagre solubility and stability, limits its application from being used as a promising drug. Several surfactants (nonionic, anionic, and cationic) have been tried to overcome the limitations of CUR. Studies suggest that the incorporation of CUR in micellar media plays a significant role in improving the solubility and stability of CUR. The choice of surfactant depends on the critical micelle concentration and the degree to which the CUR partitions into the micelles. Further, CUR-surfactant interactions can be brought about by various techniques, viz., microencapsulation, solid dispersion, and nanoemulsions. This article focuses on the influence of the micellar media on the stability, solubility, and bioavailability of CUR, along with the different methodologies used to prepare CUR-surfactant systems. Moreover, the medicinal applications of CUR-loaded surfactant systems are also briefly discussed.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"7 ","pages":"Article 100124"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143146334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigation of calcination temperature effect on crystallographic, morphological, optical, and magnetic properties of silver-doped magnesium ferrite nanoparticles 煅烧温度对掺银铁氧体镁纳米颗粒晶体学、形态学、光学和磁性能的影响

Next Nanotechnology Pub Date : 2025-01-01 DOI: 10.1016/j.nxnano.2025.100140

Sk Hasnat Taref Zim , Md Naimur Rahman Naim , Md Alamgir Hossain , Md Sohel Sikder

{"title":"Investigation of calcination temperature effect on crystallographic, morphological, optical, and magnetic properties of silver-doped magnesium ferrite nanoparticles","authors":"Sk Hasnat Taref Zim , Md Naimur Rahman Naim , Md Alamgir Hossain , Md Sohel Sikder","doi":"10.1016/j.nxnano.2025.100140","DOIUrl":"10.1016/j.nxnano.2025.100140","url":null,"abstract":"<div><div>Silver-doped magnesium ferrite was synthesized via the chemical co-precipitation method by calcination at temperatures of 800°C, 900°C, and 1000°C. At these temperatures, x-ray diffraction analysis measured crystalline sizes of 30.67, 31.09, and 41.32 nm while investigating calcination effects on interionic bond lengths, distances, and angles, thereby influencing superexchange interactions that determine the magnetic properties. SEM images showed well-defined nanoparticle sizes ranging from 349.36 to 685.53 nm, with a variation in crystal number containing 11–17. UV spectroscopy revealed optimal semiconductor behavior, with wide energy band gaps ranging from 4.77 to 5.07 eV. VSM studied the magnetic properties; coercivity varied from 705.88 to 478.24 Oe, while saturation magnetization decreased from 65.05 to 44.41 emu/g as the crystalline size increased. Notably, among the different calcination temperatures for the AMSF nanoparticles, the sample calcined at 800°C demonstrated the best performance.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"7 ","pages":"Article 100140"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143421786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fabrication of pullulan/Syzygium kanarense-ZnO nanocomposite films for effective topical treatment of diabetes-induced wounds 普绿兰/卡奈兰-氧化锌纳米复合膜的制备及其对糖尿病创面的治疗作用

Next Nanotechnology Pub Date : 2025-01-01 DOI: 10.1016/j.nxnano.2025.100176

Avinash Arasidda Kamble , BK Sarojini , MS Divakar , Vinuta Kamat , Delicia Avilla Barretto , Raju Krishna Chalannavar , Anjanapura V. Raghu

{"title":"Fabrication of pullulan/Syzygium kanarense-ZnO nanocomposite films for effective topical treatment of diabetes-induced wounds","authors":"Avinash Arasidda Kamble , BK Sarojini , MS Divakar , Vinuta Kamat , Delicia Avilla Barretto , Raju Krishna Chalannavar , Anjanapura V. Raghu","doi":"10.1016/j.nxnano.2025.100176","DOIUrl":"10.1016/j.nxnano.2025.100176","url":null,"abstract":"<div><div>In this study Zinc oxide nanoparticles (ZnONPs) were synthesized via co-precipitation using aqueous <em>Syzygium kanarense</em> (<em>Sk</em>) leaf extract, followed by successful fabrication of pullulan/<em>Sk</em>-ZnONPs composites. UV-Vis spectroscopy unveiled absorption peaks at 362 nm for <em>Sk</em>-ZnONPs and 217 nm for pullulan. FE-SEM confirmed rod-shaped nanoparticles integrated into the pullulan matrix, while PXRD aligned with ZnO ICDD reference, revealing a crystallite size of 36.89 nm and 71.2 % crystallinity. EDX and FT-IR analyses highlighted phytochemical roles in reducing and stabilizing ZnONPs. Water contact angle measurements indicated reduced hydrophilicity of the pullulan matrix upon <em>Sk</em>-ZnONPs doping. The nanocomposite exhibited potent antibacterial activity, antioxidant activity (IC<sub>50</sub>: 18.97 ± 0.28 µg, comparable to ascorbic acid), anti-inflammatory effects (IC<sub>50</sub>: 17.81 ± 0.98 µg, surpassing diclofenac sodium), and antidiabetic potential (α-amylase IC<sub>50</sub>: 16.59 ± 0.45 µg; α-glucosidase inhibition: 98.95 ± 0.57 %, rivaling acarbose). These results underscore the eco-friendly potential of pullulan/<em>Sk</em>-ZnONPs for topical treatments for diabetes-induced wounds, offering a sustainable alternative to conventional methods.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"7 ","pages":"Article 100176"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143913098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Green electrochemical synthesis of ZnO-graphene composite nanopowder and its improved antimicrobial properties zno -石墨烯复合纳米粉体的绿色电化学合成及其抗菌性能的改善

Next Nanotechnology Pub Date : 2025-01-01 DOI: 10.1016/j.nxnano.2025.100183

G. Awasthi , A.K. Pramanick , D. Mandal , M. Salot , K. Santhy , N. Jamnapara , S.K. Chaudhury

{"title":"Green electrochemical synthesis of ZnO-graphene composite nanopowder and its improved antimicrobial properties","authors":"G. Awasthi , A.K. Pramanick , D. Mandal , M. Salot , K. Santhy , N. Jamnapara , S.K. Chaudhury","doi":"10.1016/j.nxnano.2025.100183","DOIUrl":"10.1016/j.nxnano.2025.100183","url":null,"abstract":"<div><div>Zinc oxide (ZnO) nanoparticles are used as an antimicrobial agent against microorganisms. Conventionally, ZnO is prepared via chemical routes that make use of toxic and expensive chemicals. Synthesis of ZnO nanoparticles via an eco-friendly method without using toxic chemicals and enhance their antimicrobial activity are of paramount value to industries. In this study, ZnO nanoparticles were synthesized using an efficient green electrochemical oxidation process. The as-synthesized ZnO nanoparticles were characterized using X-ray diffraction (XRD), High-Resolution Scanning Electron Microscope (HRSEM), Transmission Electron Microscope (TEM), and Raman spectroscopy. The XRD analysis confirmed the synthesis of ZnO nanoparticles with a crystallite size of 24.2 nm. Antimicrobial resistance of ZnO nanopowder was enhanced by manually mixing them with 5 wt% graphene. The graphene nanoplatelets were synthesized by green electrochemical exfoliation of graphite. Raman spectroscopy confirmed the synthesis of 3–5 layers of graphene with low defect concentrations. The graphene-ZnO composite nanopowder showed an increase in potency of 121.64 % against <em>Staphylococcus aureus</em> (<em>S. aureus</em>) bacterium compared to pristine ZnO nanoparticles.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"7 ","pages":"Article 100183"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144089618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A novel Fe/S catalyst approach used to successfully synthesize 2D hexagonal boron-nitride structures 一种新型Fe/S催化剂成功合成二维六方氮化硼结构

Next Nanotechnology Pub Date : 2025-01-01 DOI: 10.1016/j.nxnano.2025.100196

Rodrigo Nunes de Souza , Mauro Francisco Pinheiro da Silva , Alysson Martins Almeida Silva , Alisson Mendes Rodrigues , Alexandre Silva Santos , Sebastião William da Silva , José Antonio Huamaní Coaquira , Wellington Marcos da Silva

{"title":"A novel Fe/S catalyst approach used to successfully synthesize 2D hexagonal boron-nitride structures","authors":"Rodrigo Nunes de Souza , Mauro Francisco Pinheiro da Silva , Alysson Martins Almeida Silva , Alisson Mendes Rodrigues , Alexandre Silva Santos , Sebastião William da Silva , José Antonio Huamaní Coaquira , Wellington Marcos da Silva","doi":"10.1016/j.nxnano.2025.100196","DOIUrl":"10.1016/j.nxnano.2025.100196","url":null,"abstract":"<div><div>The synthesis of hexagonal boron nitride (h-BN) by the chemical vapor deposition (CVD) method using a novel catalyst (Fe/S) was explored in the present study. The Fe/S catalyst was employed to enhance the yield and quality of the nanosheets. Iron serves as the primary catalyst, whereas sulfur acts as a promoter, modulating the catalytic activity and selectivity of the process. Furthermore, sulfur suppresses the surface mobility of iron, preventing excessive nanoparticle growth and maintaining an optimal size range for nanosheets nucleation. The efficient production of hexagonal boron nitride nanosheets (h-BNNS-Ox) was accomplished by using the oxidative method and subsequent exfoliation with tip ultrasound. The materials were characterized by X-ray diffraction (XRD), Raman Spectroscopy, Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), Electron Energy Loss Spectroscopy (STEM-EELS), Thermogravimetric Analysis (TGA) and Fourier-transform infrared spectroscopy (FTIR). Results show that the h-BNNS-Ox sample is a multifunctional material, as it has few layers, and in addition, the hydroxyl groups linked to the structure of the nanosheets enable covalent bonding with other functional groups of interest, which enhances and expands its application in various segments.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"7 ","pages":"Article 100196"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144222725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Stimuli-responsive nanoparticles for lung disorder treatment: From serendipity to precision phosphorylation modulation and drug repurposing 刺激反应纳米颗粒治疗肺部疾病：从意外发现到精确磷酸化调节和药物再利用

Next Nanotechnology Pub Date : 2025-01-01 DOI: 10.1016/j.nxnano.2025.100182

Nourhan Elsayed

{"title":"Stimuli-responsive nanoparticles for lung disorder treatment: From serendipity to precision phosphorylation modulation and drug repurposing","authors":"Nourhan Elsayed","doi":"10.1016/j.nxnano.2025.100182","DOIUrl":"10.1016/j.nxnano.2025.100182","url":null,"abstract":"<div><div>From the serendipitous discovery of penicillin, X-rays, and streptomycin to transformative innovations that target disease signaling pathways, all these findings have played a pivotal role in shaping pulmonary medicine. This study outlines the different categories of stimuli-responsive nanoparticles (NPs) that can encapsulate different medications. Stimuli-responsive NPs are designed to react to external triggers (e.g., light, magnetic fields) or internal triggers (e.g., pH, enzymes, temperature), enabling site-specific delivery of therapeutic agents, and offering innovative solutions for treating lung disorders. The review also emphasizes three principal phosphorylation pathways: the inflammatory NF-κB pathway, the fibrotic TGF-β pathway, and the carcinogenic IGF-1 pathway. Since NF-ӄB, TGF-β, and IGF-1 are the main signaling pathways included in many diseases in the human body, targeting these signaling pathways would treat not only lung diseases but also other diseases caused by the dysregulation of these signals. Unlike conventional therapies that use free drugs for pulmonary illnesses, the application of stimuli-responsive NPs to encapsulate serendipitous drugs and drugs aimed at phosphorylation signaling pathways exhibits improved therapeutic effectiveness and reduced toxicity. Notably, encapsulating serendipitously discovered drugs, such as statins and quinine, alongside phosphorylation-targeting agents like resveratrol and curcumin in stimuli-responsive NPs underscores the potential of drug repurposing to enhance lung disorder treatments.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"7 ","pages":"Article 100182"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144123631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Understanding the synthesis mechanism of arginine functionalized silver/silver chloride nanoparticles using sugar ligands 利用糖配体合成精氨酸功能化银/氯化银纳米粒子的机理研究

Next Nanotechnology Pub Date : 2025-01-01 DOI: 10.1016/j.nxnano.2025.100160

Şuheda Bolat , Suna Değirmenci , Abdurrahman Gümüş , Zafer Sancak , İdris Yazgan

{"title":"Understanding the synthesis mechanism of arginine functionalized silver/silver chloride nanoparticles using sugar ligands","authors":"Şuheda Bolat , Suna Değirmenci , Abdurrahman Gümüş , Zafer Sancak , İdris Yazgan","doi":"10.1016/j.nxnano.2025.100160","DOIUrl":"10.1016/j.nxnano.2025.100160","url":null,"abstract":"<div><div>In this study, we performed a mechanistic study to understand how the sugar ligand chemistry affected the morphology, size and surface chemistry of Ag/AgCl_NPs synthesized in the presence of L-Arginine hydrochloride and L-Arginine/KCl mixture. The sugar ligands Lactose <em>p</em>-methoxyaniline (LMA) and Galactose 5-aminosalicylic acid (G5AS) resulted in formation of sheet-like Ag/AgCl_NPs while Lactose sulfanilic acid (LSA) and Lactose <em>p</em>-sulfonyldianiline (LPSA) caused the formation of anisotropic and film-like Ag/AgCl_NPs. The UV-Vis based mechanistic studies showed that the presence of Arginine posed a strong effect on how G5AS and LMA ligands interact with silver ions while the effect was more complicated for the LSA and LPSA ligands due to the fact that they form complexation with Ag<sup>+</sup> ions. The mechanism was further investigated using infrared (IR) studies that showed the increases in Argine and chloride ion concentrations resulted in differentiation of the surface chemistry of the Ag/AgCl_NPs, and appearance of Arginine related IR bands became clearer in the case of co-introduction of Arginine and the sugar ligands. The characterized nanoparticles were then used as antibacterial agent for multidrug resistant <em>Escherichia coli</em> species for which less than 10 µM minimum inhibitory concentrations were obtained. The promising antibacterial activity, which could be assigned to the presence of Arginine, was independent from the sugar ligand chemistry and nanoparticles’ morphology and size. Particularly, large Ag/AgCl_NP film forming capacity can call further research to be exploited as coating materials for antibacterial application.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"7 ","pages":"Article 100160"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143768041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0