Next Nanotechnology最新文献

{"title":"Bioimaging potential: Comparative study of ZnO nanoparticles synthesized via green and chemical routes","authors":"Anjali Mehto,&nbsp;Prashant Shukla","doi":"10.1016/j.nxnano.2024.100118","DOIUrl":"10.1016/j.nxnano.2024.100118","url":null,"abstract":"<div><div>Zinc Oxide Nanoparticles (ZnO NPs) were synthesized through chemical and green synthesis methods employing Ficus religiosa (peepal) leaf extract. The synthesized nanoparticles underwent comprehensive characterization using various techniques such as Powder X-ray Diffractometry (PXRD), Fourier-transform Infrared Spectroscopy (FTIR), Scanning Electron Microscopy (SEM), Photoluminescence (PL), UV–visible Spectroscopy, and Spectroscopic Ellipsometry. The PXRD analysis confirmed a hexagonal wurtzite structure with excellent crystallinity in the product. UV–visible studies indicated band gap energies of 3.13 eV and 2.7 eV for green-synthesized and chemically synthesized ZnO NPs, respectively. There was notable augmentation in the fluorescence characteristics of ZnO NPs derived through green synthesis when compared to chemically synthesized NPs. This observed enhancement in fluorescence renders the green-synthesized ZnO NPs particularly advantageous for bio-imaging.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"7 ","pages":"Article 100118"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143146329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hydrophobic starch acetate nanoparticles: A biopolymer-based system for sustained antitubercular drug release","authors":"Gaurang Rami ,&nbsp;Pruthviraj Limbachiya ,&nbsp;Mohyuddin Maradiya ,&nbsp;Girish Acharya ,&nbsp;Jabali Vora","doi":"10.1016/j.nxnano.2024.100120","DOIUrl":"10.1016/j.nxnano.2024.100120","url":null,"abstract":"<div><div>The objective of the research was to evaluate the utilization of starch acetate nanoparticles (SANPs) as drug delivery carriers for antitubercular drugs (Isoniazid, Rifampicin, and Pyrazinamide). The SANPs were synthesized employing ultrasonic-assisted double emulsification solvent evaporation method, permitting effective drug encapsulation. Chemical modification of native starch strengthened its hydrophobicity, as indicated by lower crystallinity in XRD analysis. The TGA validated the thermal stability of SANPs. Morphological investigation indicated a beehive-like structure with constant porosity changed to evenly dispersed spherical nanoparticles when Starch acetate is converted into SANPs. Dynamic light scattering measured the particle sizes of SANPs to be 161 nm. Drug encapsulation brought up the SANPs particle size to 249 nm. Isoniazid, Rifampicin, and Pyrazinamide exhibited 72 %, 83 %, and 75 % encapsulation efficiency at a 2:1 polymer-drug ratio, respectively. In phosphate-buffered saline (pH 7.4), drug release behavior exhibited 55 %, 30 %, and 45 % release of isoniazid, rifampicin, and pyrazinamide over 24 hours. The Korsmeyer-Peppas model demonstrated non-Fickian diffusion for all drug-encapsulated SANPs. Thus, these results contribute to the development of biopolymer-based drug delivery systems for sustainable release of antitubercular drugs.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"7 ","pages":"Article 100120"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143146332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Critical review of ultra-lightweight foam materials","authors":"Ridhi Saini ,&nbsp;Dipen Kumar Rajak ,&nbsp;Tilak Joshi ,&nbsp;Dwesh Kumar Singh ,&nbsp;Venkat A.N. Chilla ,&nbsp;Sriram Sathaiah","doi":"10.1016/j.nxnano.2025.100138","DOIUrl":"10.1016/j.nxnano.2025.100138","url":null,"abstract":"<div><div>Ultra-lightweight foam (ULF) materials have emerged as transformative solutions across many industries, driven by the increasing demand for lightweight yet high-performance materials. Characterized by their low density, high porosity, and remarkable thermal insulation properties, including exceptional cushioning and shock absorption capabilities. These attributes make them essential in the aerospace, automotive, medical, and construction sectors, where efficiency and performance are paramount. Current trends in ULF materials highlight a strong commitment to sustainability by utilizing bio-based resources and recycled materials. The ULF materials revolutionize various industries by providing lightweight solutions, contributing to energy savings and reducing environmental impact. As industries increasingly prioritize sustainability and performance, ULF materials stand at the forefront of material science innovation, promising a future marked by enhanced efficiency and environmental responsibility. This review explores the classifications, manufacturing techniques, properties, applications, advantages, and challenges associated with ULF materials. This exploration aims to lighten the enormous possibilities that ULF materials present in achieving a more sustainable and high-performance future across diverse applications.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"7 ","pages":"Article 100138"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143146407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing magnetic and electrochemical properties of cobalt modified ZnS nanoparticles: A facile synthesis approach","authors":"Pawan Kumar Pathak ,&nbsp;Devendra Kumar ,&nbsp;Santosh J. Uke ,&nbsp;Amit Kumar Singh ,&nbsp;Manika Chaudhary ,&nbsp;Neha V. Brahmankar ,&nbsp;Subodh Kumar Sharma ,&nbsp;Beer Pal Singh ,&nbsp;Ashwani Kumar","doi":"10.1016/j.nxnano.2025.100133","DOIUrl":"10.1016/j.nxnano.2025.100133","url":null,"abstract":"<div><div>In this investigation, we effectively fabricated zinc sulphide (ZnS) nanoparticles doped with cobalt (Co) using the facial synthesis method at different concentrations (3 %, 6 %, and 9 %). The Co doping-dependent structural, morphological, magnetic, optical, and electrochemical properties of the ZnS nanostructures were systematically explored. The analysis of magnetic properties revealed that the ferromagnetic ZnS nanoparticles exhibited superparamagnetic behaviour, showing an increased magnetization with higher Co doping content. Electrochemical assessments of the electrodes were conducted in 1 mol L⁻¹ Na₂SO₄ liquid electrolyte. The 3 % Co doped ZnS variant, which demonstrated the highest energy density (14.27 Whkg⁻¹) at 10 mAcm⁻² and capacity retention (94.76 %) after 2000 cycles at 50 mAcm⁻². Further, a trend of a decrease in specific capacitances and energy density with an increase in Co doping is observed. This outcome implies that optimal levels of Co doping can enhance the electrochemical and magnetic performances of ZnS nanoparticles, underscoring their potential for applications in energy storage.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"7 ","pages":"Article 100133"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143146339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced electrochemical properties of NiS@CeO2 spherical nanoflakes","authors":"Indumati D. Yadav ,&nbsp;Dineshkumar Yadav ,&nbsp;Aleem Ansari ,&nbsp;Shyamalava Mazumdar ,&nbsp;Shivram S. Garje","doi":"10.1016/j.nxnano.2024.100126","DOIUrl":"10.1016/j.nxnano.2024.100126","url":null,"abstract":"<div><div>Herein we report synthesis of bare cerium oxide nanoparticles from cerium hydroxide and NiS@CeO₂ nanocomposite (NC) from nickel cinnamaldehyde thiosemicarbazone complex (single source molecular precursor) and CeO₂ nanoparticles by solvothermal method using ethylene glycol as a capping agent. These materials were characterized using powder X-ray diffraction, Fourier transform infrared spectroscopy, scanning electron microscopy, high resolution transmission electron microscopy and energy dispersive X-ray techniques. The crystallite size of the composite nanoparticles calculated using XRD is 17.99 nm. TEM shows spherical shape morphology of NiS@CeO₂ nanocomposite with average particle size less than 10 nm. Electrochemical properties of bare CeO₂ and NiS@CeO₂ NC electrodes were evaluated by cyclic voltammetry, galvanostatic charge/discharge and electrochemical impedance spectroscopy. The electrochemical measurements show that the capacitance value of NiS@CeO₂ NC electrode is significantly higher (707.84 F g⁻¹) compared to bare CeO₂ electrode (80.91 F g⁻¹) at current density 1 A g⁻¹. This can be attributed to synergistic effect in nanocomposite. The cycle stability of NiS@CeO₂ NC electrode was found to be 98.41 % even after 6000 charge–discharge cycles at 2 A g⁻¹ current density.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"7 ","pages":"Article 100126"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143146406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing magnetic hyperthermia: Investigating iron oxide nanoparticle coating and stability","authors":"Joana Santos ,&nbsp;Jorge Carvalho Silva ,&nbsp;Manuel A. Valente ,&nbsp;Tânia Vieira ,&nbsp;Paula I.P. Soares","doi":"10.1016/j.nxnano.2025.100141","DOIUrl":"10.1016/j.nxnano.2025.100141","url":null,"abstract":"<div><div>Cancer treatment research focuses on overcoming the limitations of conventional treatment methods, especially in addressing treatment-resistant malignancies. Magnetic hyperthermia (MH) is an innovative approach that uses superparamagnetic iron oxide nanoparticles (SPIONs) to increase the temperature locally, triggering cancer cell death. However, challenges related to the SPIONs coating impact their stability and MH heating mechanism, hindering its clinical adoption. This work explores diverse SPIONs coating options - oleic acid (OA), dimercaptosuccinic acid (DMSA), and (3-aminopropyl)triethoxysilane (APTES), to improve SPIONS stability under storage while keeping their heating capacity. OA- and DMSA-coated SPIONs, both negatively charged NPs, exhibited similar behavior in protein corona formation and MH tests. The heating capacity of the three types of SPIONs was maintained after 1 month of storage; however, these values significantly decreased to about 60 % of the initial value after 6 months. APTES-coated SPIONs displayed higher protein corona formation, mainly related to the positively charged surface. Interaction studies with three cell lines (fibroblasts, melanoma, and macrophages) revealed enhanced internalization of APTES-coated SPIONs. Only APTES-coated SPIONs achieved therapeutic temperatures in MH assays, reducing melanoma cell viability significantly. The study underscores the importance of nanoparticle surface modifications and the complexity of factors influencing treatment efficacy. Further research is essential for a better understanding of the cell death mechanism induced by MH and for its clinical translation.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"7 ","pages":"Article 100141"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143305669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nanoparticles assisted drug delivery for effective management of Glioblastoma","authors":"Mansi Damani ,&nbsp;Nagesh Nilawar ,&nbsp;Munira Momin ,&nbsp;Raghumani Singh Ningthoujham ,&nbsp;Tabassum Khan","doi":"10.1016/j.nxnano.2025.100137","DOIUrl":"10.1016/j.nxnano.2025.100137","url":null,"abstract":"<div><div>Glioblastoma multiforme (GBM) is one of the most aggressive forms of primary brain tumor with a dire prognosis due to its heterogeneity, invasive nature, and resistance to conventional therapies. Standard treatments, including surgery, radiotherapy, and chemotherapy with temozolomide (TMZ), are often limited by the ability of the tumor to circumvent therapeutic effects and by the physiological barriers that restrict drug delivery to the brain parenchyma. Specifically, the blood-brain barrier (BBB) and the blood-brain tumor barrier (BBTB) impede the effective concentration of therapeutic agents within the brain, posing a significant challenge in treating GBM. The primary focus of current research has pivoted towards nanotechnology to address these limitations. Due to their size, surface modifications, and capability to encapsulate drugs, nanocarriers like polymeric, metallic, and lipid nanoparticles have shown potential in enhancing the penetration of anticancer agents across the BBB and BBTB, thus increasing treatment efficacy and minimizing general toxicity. Moreover, lipid-based nanoparticles, such as solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs), offer advantages in drug encapsulation, stability, and controlled release metal nanoparticles, including gold and silver nanoparticles, provide unique properties for imaging and photothermal therapy, potentially augmenting the efficacy of conventional treatments. This review elucidates the mechanisms by which nanocarriers cross the BBB and BBTB, emphasizing the importance of physicochemical properties such as size, charge, and surface functionality. The integration of nanotechnology in GBM treatment highlights the potential for nanoparticles to revolutionize drug delivery systems, overcoming the inherent challenges posed by the BBB and the tumor microenvironment. The promise of nanomedicine advances in this field could lead to more effective therapeutic strategies, significantly impacting patient outcomes in GBM management.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"7 ","pages":"Article 100137"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143146414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Decentralized electrochemical biosensors for biomedical applications: From lab to home","authors":"Pramod K. Kalambate ,&nbsp;Vipin Kumar ,&nbsp;Dhanjai","doi":"10.1016/j.nxnano.2024.100128","DOIUrl":"10.1016/j.nxnano.2024.100128","url":null,"abstract":"<div><div>Integrated electrochemical biosensors represent the new generation of sensing tools in the biomedical field, delivering compact-sized, portable, wearable, and implantable devices. Advances in sensor fabrication methods, scalable material synthesis, microelectronics, flexible electronics, and wireless communication have enabled the evolution of biosensing devices from traditional hospital-centric systems to home-centric solutions, suitable for use by non-experts to analyze early signs of diseases. Despite these advancements, key challenges remain, including scalability, material durability, power management, and seamless integration of biosensor components into user-friendly platforms. The translation of these technologies involves strategies to overcome these challenges, such as developing cost-effective manufacturing methods and optimizing device design for real-world applications. Furthermore, the integration of these devices with the Internet-of-Things (IoT), Internet-of-Medical-Things (IoMT), artificial intelligence (AI), and machine learning (ML) algorithms has demonstrated breakthrough technological solutions for healthcare management, disease prognosis, and patient care. However, potential risks such as data security vulnerabilities, privacy concerns, and regulatory challenges must be addressed to ensure safe and ethical deployment of these technologies. Herein, we provide an in-depth analysis of the evolution of conventional electrochemical biosensors into miniaturized, integrated devices, focusing on their potential for better healthcare management and highlighting associated technical, regulatory, and ethical challenges. We also highlight key aspects of 6th generation sensing technology. Additionally, the role of IoT and AI-assisted technologies is critically discussed, presenting both their transformative benefits and the risks they pose in the biomedical field.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"7 ","pages":"Article 100128"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143146330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Next-generation nanocomposites: Optimizing Al2O3-CuO-ZnO and reduced graphene oxide for enhanced performance","authors":"Rahul Sharma ,&nbsp;Harish Kumar ,&nbsp;Rajni Kumari ,&nbsp;Gaman Kumar ,&nbsp;Bhawna Swami ,&nbsp;Antresh Kumar ,&nbsp;Gita Rani ,&nbsp;Ramesh Kumar","doi":"10.1016/j.nxnano.2024.100119","DOIUrl":"10.1016/j.nxnano.2024.100119","url":null,"abstract":"<div><div>Exceptional reduced graphene oxide-based nanocomposites (NCs) were synthesized using Al₂O₃-CuO-ZnO (ACZ) nanoparticles (NPs) through a controlled hydrothermal method. Nanomaterials with improved optical, magnetic, antibacterial, adsorption, anticorrosive, and photocatalytic characteristics were synthesized, showing synergistic behavior. To understand key structural features, the NCs were thoroughly examined using energy-dispersive X-ray analysis, SEM, X-ray diffraction, FTIR, and UV-Vis. spectroscopy. Adding ACZ NPs in the rGO matrix, increased magnetic, anticorrosive, improved antibacterial efficacy against Gram-positive bacteria, and photocatalytic activities. The NCs were exposed to sunlight and UVA and UVB light to degrade methylene blue (MB) dye i.e., 89.21 % in 75 min. The anti-corrosive characteristics (95.9 %) were examined against mild steel using a 1.0 N H₂SO₄ at room temperature at a very low concentration i.e., 10 ppm. The magnetic behavior of the NCs was examined with the help of Gouy’s balance. The induced current showed a clear relationship to the applied magnetic field strength, indicating that the NCs are paramagnetic. The antibacterial effects of the NCs were evaluated against <em>S. aureus</em> and <em>E. coli</em> at different concentrations. The ACZ@rGO NCs exhibited exceptional versatility, showing great promise for water purification, adsorption, corrosion protection, photocatalytic processes, biomedical technologies, and environmental restoration.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"7 ","pages":"Article 100119"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143146331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Colletotrichum gloeosporioides (endophytic fungi) mediated biosynthesis of TiO2 nanoparticles for high-performance dye-sensitized solar cell","authors":"Sakshi Singh ,&nbsp;Shubham Sharma ,&nbsp;Rajnish Bharti ,&nbsp;Ravindra Nath Kharwar ,&nbsp;Pankaj Srivastava","doi":"10.1016/j.nxnano.2024.100122","DOIUrl":"10.1016/j.nxnano.2024.100122","url":null,"abstract":"<div><div>This work reports an environmentally friendly protocol for synthesizing TiO₂ nanoparticles (NPs) by utilizing endophytic fungi, <em>Colletotrichum gloeosporioides (C. gloeosporioides)</em>. The fungi isolated from Thevetia peruviana, worked as a bio-capping agent to regulate the growing TiO₂ NPs morphology and agglomeration behavior. The formation of TiO₂ NPs was validated by surface plasmon resonance, observed using UV–vis spectroscopy. Using XRD and HRTEM, the structure, size, and shape of the as-synthesized anatase TiO₂ NPs were characterized. BET analysis was used to examine the surface area and porosity. EIS revealed the greater charge collection efficiency and enhanced electron lifetime for the TiO₂ obtained with N-3 (endophytic fungal extract). The dye-sensitized solar cell (DSSC) fabricated with bio-capped TiO₂ (N-3) photoanode exhibited greater light-to-current conversion efficiency, 3.50 %; much enhanced compared to 0.98 % obtained with un-capped TiO₂ NPs (N-1) based cell. The study demonstrated that the endophytic fungus <em>C.gloeosporioides</em> played a vital role in enhancing the cell performance.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"7 ","pages":"Article 100122"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143146336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}