Next Nanotechnology最新文献

{"title":"Hydrophobic starch acetate nanoparticles: A biopolymer-based system for sustained antitubercular drug release","authors":"Gaurang Rami ,&nbsp;Pruthviraj Limbachiya ,&nbsp;Mohyuddin Maradiya ,&nbsp;Girish Acharya ,&nbsp;Jabali Vora","doi":"10.1016/j.nxnano.2024.100120","DOIUrl":"10.1016/j.nxnano.2024.100120","url":null,"abstract":"<div><div>The objective of the research was to evaluate the utilization of starch acetate nanoparticles (SANPs) as drug delivery carriers for antitubercular drugs (Isoniazid, Rifampicin, and Pyrazinamide). The SANPs were synthesized employing ultrasonic-assisted double emulsification solvent evaporation method, permitting effective drug encapsulation. Chemical modification of native starch strengthened its hydrophobicity, as indicated by lower crystallinity in XRD analysis. The TGA validated the thermal stability of SANPs. Morphological investigation indicated a beehive-like structure with constant porosity changed to evenly dispersed spherical nanoparticles when Starch acetate is converted into SANPs. Dynamic light scattering measured the particle sizes of SANPs to be 161 nm. Drug encapsulation brought up the SANPs particle size to 249 nm. Isoniazid, Rifampicin, and Pyrazinamide exhibited 72 %, 83 %, and 75 % encapsulation efficiency at a 2:1 polymer-drug ratio, respectively. In phosphate-buffered saline (pH 7.4), drug release behavior exhibited 55 %, 30 %, and 45 % release of isoniazid, rifampicin, and pyrazinamide over 24 hours. The Korsmeyer-Peppas model demonstrated non-Fickian diffusion for all drug-encapsulated SANPs. Thus, these results contribute to the development of biopolymer-based drug delivery systems for sustainable release of antitubercular drugs.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"7 ","pages":"Article 100120"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143146332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Critical review of ultra-lightweight foam materials","authors":"Ridhi Saini ,&nbsp;Dipen Kumar Rajak ,&nbsp;Tilak Joshi ,&nbsp;Dwesh Kumar Singh ,&nbsp;Venkat A.N. Chilla ,&nbsp;Sriram Sathaiah","doi":"10.1016/j.nxnano.2025.100138","DOIUrl":"10.1016/j.nxnano.2025.100138","url":null,"abstract":"<div><div>Ultra-lightweight foam (ULF) materials have emerged as transformative solutions across many industries, driven by the increasing demand for lightweight yet high-performance materials. Characterized by their low density, high porosity, and remarkable thermal insulation properties, including exceptional cushioning and shock absorption capabilities. These attributes make them essential in the aerospace, automotive, medical, and construction sectors, where efficiency and performance are paramount. Current trends in ULF materials highlight a strong commitment to sustainability by utilizing bio-based resources and recycled materials. The ULF materials revolutionize various industries by providing lightweight solutions, contributing to energy savings and reducing environmental impact. As industries increasingly prioritize sustainability and performance, ULF materials stand at the forefront of material science innovation, promising a future marked by enhanced efficiency and environmental responsibility. This review explores the classifications, manufacturing techniques, properties, applications, advantages, and challenges associated with ULF materials. This exploration aims to lighten the enormous possibilities that ULF materials present in achieving a more sustainable and high-performance future across diverse applications.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"7 ","pages":"Article 100138"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143146407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bioimaging potential: Comparative study of ZnO nanoparticles synthesized via green and chemical routes","authors":"Anjali Mehto,&nbsp;Prashant Shukla","doi":"10.1016/j.nxnano.2024.100118","DOIUrl":"10.1016/j.nxnano.2024.100118","url":null,"abstract":"<div><div>Zinc Oxide Nanoparticles (ZnO NPs) were synthesized through chemical and green synthesis methods employing Ficus religiosa (peepal) leaf extract. The synthesized nanoparticles underwent comprehensive characterization using various techniques such as Powder X-ray Diffractometry (PXRD), Fourier-transform Infrared Spectroscopy (FTIR), Scanning Electron Microscopy (SEM), Photoluminescence (PL), UV–visible Spectroscopy, and Spectroscopic Ellipsometry. The PXRD analysis confirmed a hexagonal wurtzite structure with excellent crystallinity in the product. UV–visible studies indicated band gap energies of 3.13 eV and 2.7 eV for green-synthesized and chemically synthesized ZnO NPs, respectively. There was notable augmentation in the fluorescence characteristics of ZnO NPs derived through green synthesis when compared to chemically synthesized NPs. This observed enhancement in fluorescence renders the green-synthesized ZnO NPs particularly advantageous for bio-imaging.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"7 ","pages":"Article 100118"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143146329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phyto-mediated synthesis of silver nanoparticles using Erythrina variegata L. leaf extract and evaluation of their anti-bacterial, anti-Alzheimer, antioxidant and cytotoxic activities","authors":"Gangadhar Kodiyala ,&nbsp;Kandrakonda Yelamanda Rao ,&nbsp;Venakata Pratyusha Chapati ,&nbsp;Kana Meenugula ,&nbsp;Jayaraju Nadimikeri ,&nbsp;Sunitha Salkapuram ,&nbsp;Rajesh Nambi ,&nbsp;Gangaiah Damu Amooru ,&nbsp;Madakka Mekapogu","doi":"10.1016/j.nxnano.2025.100157","DOIUrl":"10.1016/j.nxnano.2025.100157","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Background&lt;/h3&gt;&lt;div&gt;Owing to their growing prevalence, multi-drug-resistant bacterial infections, Alzheimer’s disease and cancer has emerged as a global health concern. To combat this real threat to humankind, biogenic silver nanoparticles (AgNPs) are considered as a prime strategy due to its wide-range of medical applications.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Objectives&lt;/h3&gt;&lt;div&gt;The current study was aimed to investigate the green synthesis of silver nanoparticles using aqueous leaf extract of &lt;em&gt;Erythrina variegata&lt;/em&gt; and evaluation of anti-Alzheimer, antioxidant and anti-cancer efficacies.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Method&lt;/h3&gt;&lt;div&gt;The aqueous extract was prepared and initially assessed for its phytochemical composition. Then silver nanoparticles (AgNPs) were synthesized by reducing aqueous AgNO&lt;sub&gt;3&lt;/sub&gt; with aqueous leaf extract at nonphotomediated conditions, without any catalyst, template or surfactant. The Ev-AgNPs were characterized by ultraviolet-visible (UV–VIS) &amp; Fourier-transform infrared (FTIR) spectroscopy, zeta sizer, scanning electron microscopy (SEM), energy-dispersive X-ray (EDXA) and X-ray diffraction (XRD) analysis. The bio-activities of extract and Ev-AgNPs including antibacterial, anti-oxidant, anti-Alzheimer’s and anticancer activities were evaluated using well diffusion, ABTS &amp; DPPH radical scavenging, Ellman’s and MTT assays, respectively.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;Phytochemical analysis revealed the leaf extract of &lt;em&gt;E. variegata&lt;/em&gt; as rich source of flavonoids and phenolics. Physicochemical and morphological characterization inferred that Ev-AgNPs were spherical in shape, small in size (59.5–90.2 nm), crystalline in nature with high stability (−38.8 mV) and associated with capping agents. In biological evaluation, extract of &lt;em&gt;E. variegata&lt;/em&gt; disclosed good activities, however, better potencies were noticed with Ev-AgNPs. Biogenic Ev-AgNPs exhibited high ABTS and DPPH radical scavenging abilities with IC&lt;sub&gt;50&lt;/sub&gt; values of 38.47 and 17.73 µg/mL, respectively. Ev-AgNPs had highest antibacterial activity against &lt;em&gt;Escherichia coli&lt;/em&gt; and &lt;em&gt;Pseudomonas aeruginosa&lt;/em&gt;, good activity with &lt;em&gt;Bacillus subtilis&lt;/em&gt; and &lt;em&gt;Staphylococcus aureus&lt;/em&gt;, while least inhibition zone against &lt;em&gt;Pseudomonas syringae&lt;/em&gt;. Ev-AgNPs displayed remarkable cytotoxicity against human breast cancer cell line MCF–7 with 53.11 % inhibition at a concentration of 0.5 µg/mL. Ev-AgNPs were found to be non-haemolytic in nature. In Elmann assay, Ev-AgNPs excelled high inhibitory efficiencies against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) with IC&lt;sub&gt;50&lt;/sub&gt; values of 15.18 and 56.21 µg/mL, respectively with mixed mode of inhibition.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusion&lt;/h3&gt;&lt;div&gt;Based on these findings, it appears that Ev-AgNPs have promise as multi target directed ligand effective against bacterial infections, breast cancer, Alzheimer’s disease and also oxidative stress mediated illnesses.&lt;/div&gt;&lt;","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"7 ","pages":"Article 100157"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143783146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hydrothermal synthesis of nano-metal oxides for structural modification: A review","authors":"Tasnimul Quader Tazim ,&nbsp;Md. Kawsar ,&nbsp;Md. Sahadat Hossain ,&nbsp;Newaz Mohammed Bahadur ,&nbsp;Samina Ahmed","doi":"10.1016/j.nxnano.2025.100167","DOIUrl":"10.1016/j.nxnano.2025.100167","url":null,"abstract":"<div><div>Materials with a minimum of one dimension less than 100 nanometers (nm) are referred to as nanomaterials (NMs), granting them unique and intriguing properties due to their minimal size. NMs exhibit unique thermal, magnetic, optical, and chemical properties that distinguish them significantly from larger molecules such as micromolecular, bulk organic, or inorganic compounds. Metal oxide NMs are utilized in the medical sector for targeted drug delivery, environmental science for pollution management and water treatment, and electronics to improve energy production. Because of the rapidly growing demand for nanomaterials with precise morphological properties for specific applications, significant research efforts have been directed toward developing hydrothermal synthetic methodologies under various reaction conditions to achieve both scientifically and practically novel results. Several studies have been conducted to study the impact of various response parameters on the fundamental characteristics and morphology of MNs. Therefore, this review paper discussed the hydrothermal synthesis under different reaction conditions for seven important metal oxides (ZnO, CuO, Fe₂O₃, CdO, TiO₂, Al₂O₃, and CaO). Furthermore, it analyzes how utilizing varied source materials alongside diverse reaction parameters affects the structural morphology of these nanoscale materials, facilitating their development for specific applications.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"7 ","pages":"Article 100167"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143859906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lysozyme functionalized zinc-oxide nanoparticles: Synthesis, characterization, and antibacterial assessment against Staphylococcus aureus with futuristic application in wastewater monitoring","authors":"Suneeti Singh,&nbsp;Pavni Rekhi,&nbsp;Jewel Mary Saju","doi":"10.1016/j.nxnano.2025.100222","DOIUrl":"10.1016/j.nxnano.2025.100222","url":null,"abstract":"<div><div>Access to clean drinking water remains a global concern, primarily due to the presence of biological, inorganic, and organic pollutants. Among the biological contaminants, waterborne pathogens pose a significant threat to human well-being. Since nanoparticle-based biosensors have a higher sensitivity for detecting bacteria than conventional detection techniques, they have become increasingly prevalent. In this context, the current study reports zinc oxide nanoparticles functionalized with lysozyme (ZnO@LY NPs) via a modified oxidation-reduction mechanism, followed by an assessment of their antibacterial activity. The morphology and size of the functionalized ZnO@LY NPs were determined using Transmission electron microscopy-energy dispersive X-ray spectroscopy (TEM-EDX), X-ray diffraction (XRD), dynamic light Scattering (DLS), and zeta potential analysis, which revealed nanoparticles of size between 14 and 32 nm with + 31.1 mV charge. Further, the functionalization of ZnO with lysozyme was confirmed using Fourier-transform infrared spectroscopy (FTIR) and Ultraviolet-Visible (UV-Vis) spectroscopy. The antibacterial efficacy of ZnO@LY NPs and ZnO NPs against Gram-positive bacteria (<em>Staphylococcus aureus</em>) was assessed in a comparative study. After 30 min and 24 h of treatment with ZnO@LY NPs at 250 ppm, the agar spot assay revealed the absence of colonies. Similarly, ZnO@LY NPs exhibited a 25 % stronger and statistically significant antibacterial impact than non-functionalized ZnO NPs in the bacterial growth inhibition assay, as confirmed by repeated measures (RM)-ANOVA analysis. Moreover, Dunnett's multiple comparison test revealed that ZnO@LY NPs showed a dose-dependent linear response when compared to ZnO NPs. The superior antibacterial performance of ZnO@LY NPs is attributed to improved bacterial surface interactions, stability, and biocompatibility facilitated by lysozyme functionalization. These findings suggest a potential application of ZnO@LY nanoparticles in biosensors for on-site pathogen detection in wastewater.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"8 ","pages":"Article 100222"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144655893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Solid lipid nanoparticles based drug delivery for major infectious diseases: A narrative review","authors":"Vivek Kumar","doi":"10.1016/j.nxnano.2025.100228","DOIUrl":"10.1016/j.nxnano.2025.100228","url":null,"abstract":"<div><div>Solid lipid nanoparticles (SLNs) have long been recognized as a promising and versatile lipid-based drug delivery system. This approach offers an alternative to conventional drug delivery methods by utilizing nanocarriers while overcoming many of their inherent limitations. SLNs possess several advantages, including ease of fabrication, scalability for commercial production, low toxicity, a large encapsulation capacity, and suitability for oral administration. However, research on the application of SLNs in infectious diseases remains highly fragmented. This review aims to consolidate current knowledge on the effectiveness of SLNs in delivering drugs to treat infections caused by bacteria, fungi, viruses, and parasites. Particular attention is given to diseases associated with <em>Mycobacterium</em>, ESKAPE pathogens, <em>Candida</em> spp., <em>Fusarium</em> spp., HIV, SARS-CoV-2, <em>Leishmania</em> spp., <em>Trypanosoma</em> spp., and <em>Plasmodium</em> spp. Additionally, this review highlights key studies published by various research groups investigating SLN-based drug delivery for these pathogens and diseases.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"8 ","pages":"Article 100228"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144721560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Heat generation and Joule dissipation influence on Magnetohydrodynamic Cu- H2O and Al2O3-H2O nanofluid convection with nanoparticle volume fraction and ramped and isothermal wall temperature: A finite element approach","authors":"Thirupathi Thumma ,&nbsp;Surender Ontela ,&nbsp;Rupalakshmi Dharanikota","doi":"10.1016/j.nxnano.2025.100261","DOIUrl":"10.1016/j.nxnano.2025.100261","url":null,"abstract":"<div><div>In high-performance thermal engineering systems such as energy storage units, electronic cooling devices, and rotating heat exchangers, the combined effects of internal heat generation and viscous dissipation play a vital role in modulating heat and mass transfer during hydromagnetic nanofluid flow over vertical surfaces, especially in a rotating frame. Motivated by these practical demands, the present study is devoted to a comprehensive finite element analysis of the combined impact of heat source/sink and Joule heating on magnetohydrodynamic convection of Cu–H₂O and Al₂O₃–H₂O nanofluids, with varying nanoparticle volume fractions under ramped and isothermal wall thermal conditions. A system of nonlinear, dimensionless partial differential equations is numerically solved using the Galerkin-based finite element method (GFEM). Significant observations for the influence of various governing parameters are the elevation of thermal distribution with intensified heat source and Eckert number, while the buoyancy ratio was found to enhance momentum transfer across the fluid domain. Between the two nanofluids, <span><math><mrow><mi>Cu</mi><mo>−</mo><mi>H</mi><mi>₂</mi><mi>O</mi></mrow></math></span> consistently exhibited superior transport characteristics over <span><math><mrow><mi>Al</mi><mi>₂</mi><mi>O</mi><mi>₃</mi><mo>−</mo><mi>H</mi><mi>₂</mi><mi>O</mi></mrow></math></span>, attributed to its enhanced thermal conductivity and lower dynamic viscosity. The accuracy of the simulation is validated by benchmarking the computed values of skin friction, Nusselt number, and Sherwood number against established solutions in limiting scenarios, yielding excellent agreement. This study finds critical applications in the design and optimization of rotating chemical reactors, nano-enhanced energy systems, and magnetically controlled thermal processing equipment.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"8 ","pages":"Article 100261"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145026669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A systematic review of integration frameworks of nanomaterials in additive manufacturing processes","authors":"T.A. Mukalay","doi":"10.1016/j.nxnano.2025.100259","DOIUrl":"10.1016/j.nxnano.2025.100259","url":null,"abstract":"<div><div>This study examines the integration frameworks of nanomaterials into Additive Manufacturing (AM) processes. While nanomaterials offer improved mechanical, thermal, and electrical properties, their integration in AM process faces challenges. This study reviews works from the last decade as well as analyses existing integration frameworks. The findings demonstrate that inconsistent mechanical properties, material instability, non-uniform dispersion, limited scalability, inconsistent thermal properties, and biocompatibility are the key obstacles to nanomaterials integration in AM. Furthermore, the study investigates the gaps in current integration frameworks and proposes theoretical optimizations to address these limitations and improve outcomes of nanomaterials-enabled AM processes.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"8 ","pages":"Article 100259"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145026665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biogenic nanoparticles: Understanding their potential role in cancer theranostics","authors":"Durdana Yasin ,&nbsp;Neha Sami ,&nbsp;Bushra Afzal ,&nbsp;Almaz Zaki ,&nbsp;Haleema Naaz ,&nbsp;Shaheen Husain ,&nbsp;Tabassum Siddiqui ,&nbsp;Moshahid Alam Rizvi ,&nbsp;Tasneem Fatma","doi":"10.1016/j.nxnano.2025.100149","DOIUrl":"10.1016/j.nxnano.2025.100149","url":null,"abstract":"<div><div>Cancer has been a disease that is responsible for the maximum number of deaths around the globe. Despite so many drugs and available treatments, researchers aim to find a more efficient treatment modality with target-specificity and less toxicity. Nanotechnology has promising potential in the development of such drugs. Nanomaterials are smaller in size, possess large surface area and some very unique properties that could potentiate their usage in the cancer treatment. This review aims to impart information on the latest development in the biomedical application of biogenic nanoparticles (NPs) in preventing, diagnosis, and cancer therapy. The authors intend to give insight into developing bio-based nano-systems to warrant their use for increased specific targeting of the cancerous cells. Indeed, biogenic NPs hold great promise in cancer theranostics, offering potential advancements in both diagnosis and treatment. Key future directions include optimizing synthesis for enhanced stability and targeting, combining NPs with gene or immunotherapy for multi-modal approaches, and integrating them with advanced imaging technologies. Scaling up production while maintaining cost-effectiveness and sustainability will be essential for clinical translation.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"8 ","pages":"Article 100149"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143636672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}