Next Nanotechnology最新文献

{"title":"Biogenic nanoparticles: Understanding their potential role in cancer theranostics","authors":"Durdana Yasin ,&nbsp;Neha Sami ,&nbsp;Bushra Afzal ,&nbsp;Almaz Zaki ,&nbsp;Haleema Naaz ,&nbsp;Shaheen Husain ,&nbsp;Tabassum Siddiqui ,&nbsp;Moshahid Alam Rizvi ,&nbsp;Tasneem Fatma","doi":"10.1016/j.nxnano.2025.100149","DOIUrl":"10.1016/j.nxnano.2025.100149","url":null,"abstract":"<div><div>Cancer has been a disease that is responsible for the maximum number of deaths around the globe. Despite so many drugs and available treatments, researchers aim to find a more efficient treatment modality with target-specificity and less toxicity. Nanotechnology has promising potential in the development of such drugs. Nanomaterials are smaller in size, possess large surface area and some very unique properties that could potentiate their usage in the cancer treatment. This review aims to impart information on the latest development in the biomedical application of biogenic nanoparticles (NPs) in preventing, diagnosis, and cancer therapy. The authors intend to give insight into developing bio-based nano-systems to warrant their use for increased specific targeting of the cancerous cells. Indeed, biogenic NPs hold great promise in cancer theranostics, offering potential advancements in both diagnosis and treatment. Key future directions include optimizing synthesis for enhanced stability and targeting, combining NPs with gene or immunotherapy for multi-modal approaches, and integrating them with advanced imaging technologies. Scaling up production while maintaining cost-effectiveness and sustainability will be essential for clinical translation.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"8 ","pages":"Article 100149"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143636672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nanostructured materials for breast cancer therapeutics enhancing drug delivery through nanofibers, nano-mesh, and nanoflowers","authors":"Navya Aggarwal,&nbsp;Shreya Gupta,&nbsp;Shinjini Sen,&nbsp;Tanmay J. Urs,&nbsp;Banashree Bondhopadhyay","doi":"10.1016/j.nxnano.2025.100159","DOIUrl":"10.1016/j.nxnano.2025.100159","url":null,"abstract":"<div><div>Breast cancer drug delivery systems rely heavily on conventional routes of administration through adjuvant formulations. These systems have been under development for decades to deduce safer, bioavailable, specific, selective and efficacious modalities. Nanotechnology based drug delivery systems proposed to solve these issues, have led to a boom in nanoparticle based, liposomal, nanovesicles, nanocapsules, and similar provisions. The improvement of the existing available systems inspired biodegradable nanostructures such as nanofibers, nanomesh and nanoflowers. These structures provide better opportunities to improve targetability, bioavailability, better safety profiles. The platforms additionally facilitate controlled release of the loaded drugs. This minireview explores nanofibers, nanomesh and nanoflowers in breast cancer treatment as emerging nanostructures for delivery of chemotherapeutics. Nanofibers emulate the natural extracellular matrix which can be modified for biodegradability and tumor identification. Nanomesh provide large drug-antigen loading platform with interwoven strands.On the other hand, nanoflowers can be conveniently modulated to control the release of the drug. These nanostructures offer innovative solutions to the typical drawbacks of drug absorption, selectivity and delivery on tumor sight. In this minireview, we aim to comprehensively present how these nanostructures are created, address their mechanism of action and how they are developing the landscape of breast cancer drug delivery systems.The study prioritizes these nanostructures over their conventional counterparts due to their visible benefits while also addressing their limitations which should be further researched upon, for breast cancer therapeutics.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"8 ","pages":"Article 100159"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143820588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Zinc oxide-nanoparticle impregnated poultry droppings activated carbon for model oil desulfurization: Experimental investigation and regression modelling with uncertainty quantification","authors":"Kazeem K. Salam ,&nbsp;Idayat A. Olowonyo ,&nbsp;Kehinde A. Babatunde ,&nbsp;Monsuru O. Dauda ,&nbsp;Dauda O. Araromi ,&nbsp;Mujidat O. Aremu ,&nbsp;Opeoluwa D. Sole-Adeoye ,&nbsp;Temitope O. Adesina","doi":"10.1016/j.nxnano.2025.100164","DOIUrl":"10.1016/j.nxnano.2025.100164","url":null,"abstract":"<div><div>This study presents a novel, eco-friendly approach for adsorptive desulfurization, utilizing Poultry Droppings (PD) and Garlic Peel (GP) wastes to develop a high-performance green adsorbent for the removal of Dibenzothiopene (DBT) from Model Oil (MO). PD was thermally and chemically modified to PD-Activated Carbon (PDAC) and PDAC impregnated with Zinc Oxide Nanoparticles (PDAC-ZnO-NPs). The produced adsorbents (PDAC and PDAC-ZnO-NPs) were appropriately characterized. Batch adsorption experiment was designed by Definitive Screening Design (DSD) for parameters: adsorption temperature (25 – 50°C), contact time (10 – 60 min), agitation rate (50 – 250 rpm), and adsorbent dosage (50 – 250 mg). ZnO nanoparticle impregnation increased the surface area from 965 m²/g to 981 m²/g and enhanced the availability of oxygen-containing functional groups, thereby improving DBT affinity. The BET surface area increased from 965 m²/g to 981 m²/g after ZnO-NP impregnation, indicating enhanced adsorption capacity. The equilibrium data for DBT removal were fitted to isotherm, kinetic, and thermodynamic models, with model constants evaluated. The desulfurization process achieved an optimum DBT percentage removal (%DBTR) of 85.47 % with PDAC and 95.12 % with PDAC-ZnO-NPs. The desulfurization equilibrium data fitted the Freundlich isotherm, the Pseudo-Second-Order (PSO) kinetic model and, thermodynamic analysis indicated that DBT removal process was spontaneous and endothermic, with entropy (ΔS) and enthalpy (ΔH) changes of 140.12 J/mol·K and 40.25 kJ/mol for PDAC, and 110.49 J/mol·K and 30.01 kJ/mol for PDAC-ZnO-NPs respectively. The %DBTR decreased by 6.1 % for PDAC-ZnO-NPs after five regeneration cycles, demonstrating its reusability. This study demonstrates the potential of sustainable bio-based adsorbents for efficient adsorptive desulfurization, paving the way for cleaner fuel production and enhanced environmental sustainability.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"8 ","pages":"Article 100164"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143844262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing mechanical and tribological performance of poly(ether-ether-ketone)/hydroxyapatite nanocomposites with flower-like zinc oxide for bone replacement","authors":"Monica Rufino Senra ,&nbsp;Igor Tenório Soares ,&nbsp;Vanessa Kapps ,&nbsp;Marcia Marie Maru ,&nbsp;Maria de Fatima Vieira Marques","doi":"10.1016/j.nxnano.2025.100143","DOIUrl":"10.1016/j.nxnano.2025.100143","url":null,"abstract":"<div><div>Driven by population aging, rising obesity rates, sports injuries, and road traffic accidents, the global orthopedic implant market is projected to reach US$79.5 billion by the end of this decade, highlighting the growing demand for durable and high-performance implant materials. Poly(ether-ether-ketone) (PEEK) has emerged as a promising alternative to traditional metallic implants due to its biocompatibility, excellent tribological properties, and mechanical characteristics similar to human bone. However, its bioinert nature limits osseointegration, affecting long-term implant stability. This study presents the development of PEEK-based nanocomposites reinforced with hydroxyapatite (HA) to promote osseointegration and zinc oxide (ZnO) nanoparticles in spherical (cZnO) and flower-like (fZnO) morphologies to enhance tribological performance. The nanocomposites were evaluated through scratch testing, providing quantitative insights into their mechanical and wear resistance properties. The results demonstrated that fZnO significantly improved scratch resistance, reducing residual scratch depth by 34 % compared to cZnO-reinforced composites. Moreover, while the addition of HA did not compromise the reinforcing effect of fZnO, the cZnO-HA hybrid nanocomposite exhibited a 20 % lower coefficient of friction (COF), which could be problematic for implant stability due to potential loosening. In contrast, the fZnO-HA hybrid nanocomposite demonstrated superior scratch resistance, lower pile-up formation, and improved fixation, making it a particularly promising candidate for load-bearing orthopedic applications such as hip prosthesis stems. These findings confirm that nanoparticle morphology plays a critical role in optimizing mechanical and tribological performance in PEEK-based nanocomposites, paving the way for advanced biomaterials with enhanced wear resistance and durability.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"7 ","pages":"Article 100143"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143464182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of bridging the gap between Artificial Intelligence and nanomedicine in healthcare","authors":"Divyam Mishra ,&nbsp;Bhavishya Chaturvedi ,&nbsp;Vishal Soni ,&nbsp;Dhairya Valecha ,&nbsp;Megha Goel ,&nbsp;Jamilur R. Ansari","doi":"10.1016/j.nxnano.2025.100203","DOIUrl":"10.1016/j.nxnano.2025.100203","url":null,"abstract":"<div><div>Nanotechnology encompasses the engineering and manipulation of materials at the nanoscale (10⁻⁹ m), focusing on the development and application of novel structures and concepts. Concurrently, Artificial Intelligence (AI) simulates human cognitive processes, enabling machines to make decisions and solve problems. Within AI, subfields such as Machine Learning and Deep Learning leverage vast datasets to predict outcomes based on historical trends. This research examines the intersection of AI and nanotechnology within the medical sector, with an emphasis on illness localization, diagnosis, and therapeutic interventions. AI's deployment in molecular imaging has proven invaluable for early disease detection and treatment via biosensors. A key aspect of our analysis is the utilization of AI to formulate personalized treatment plans, enhancing the probability of achieving optimal drug-patient synergy. Additionally, we explore the development of AI-powered nanobots, capable of autonomous logical reasoning to target malignant cells for localized cancer therapy. The optimization of AI-driven drug delivery systems using nanoparticles demonstrates significant potential for surpassing the efficacy of existing delivery mechanisms. We will also assess the long-term implications of lipid nanoparticles in drug delivery applications. Machine Learning algorithms are employed to create data-driven adaptive nanomaterials and paradigms, further advancing the field. Furthermore, this study investigates the application of AI in predicting nanomedicine interactions with biological systems, aiming to establish AI-enabled platforms for personalized nanomedicine therapies. In summary, our work highlights the synergistic potential of AI and nanotechnology in catalyzing breakthroughs in medical innovation.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"8 ","pages":"Article 100203"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144365284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advanced approaches in lung cancer therapy–Exploring the unique role of Multiwalled Carbon Nanotubes","authors":"Pushpendra Kumar Khangar ,&nbsp;Vivek Daniel","doi":"10.1016/j.nxnano.2025.100180","DOIUrl":"10.1016/j.nxnano.2025.100180","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Hypothesis&lt;/h3&gt;&lt;div&gt;This paper hypothesizes that Multiwalled Carbon Nanotubes (MWCNTs) can serve as effective nanocarriers for anticancer drug delivery in lung cancer therapy. Their high surface area, biocompatibility, and adaptable surface chemistry make them promising candidates for enhancing drug delivery efficiency. MWCNTs offer the potential to enable targeted transport of anticancer drugs directly to lung cancer cells, reducing systemic toxicity through controlled and prolonged drug release while also improving drug clearance mechanisms. However, despite these advantages, the study acknowledges significant concerns regarding toxicity, biocompatibility, and long-term safety. Addressing these challenges is crucial for the successful clinical translation of MWCNT-based drug delivery systems.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Experiments (review-based analysis)&lt;/h3&gt;&lt;div&gt;Although this study does not conduct direct experiments, it reviews existing research and experimental findings on the incorporation of anticancer drugs into Multiwalled Carbon Nanotubes (MWCNTs), which involves efficient loading and release methods that ensure drug stability and retention within the nanocarrier system. These approaches enhance the controlled delivery of therapeutic agents, preventing premature degradation and maximizing efficacy. MWCNTs play a crucial role in drug delivery by improving circulation, enabling controlled release, and minimizing systemic toxicity. Additionally, surface modifications of MWCNTs contribute to better drug delivery efficiency by enhancing solubility and targeting capabilities. However, concerns regarding safety and biocompatibility remain critical. Preclinical studies have been conducted to evaluate the toxicity, biodegradability, and inflammatory response associated with MWCNTs. Surface modifications have been explored as a strategy to mitigate adverse effects, improve cellular compatibility, and enhance the overall feasibility of MWCNT-based drug delivery systems for lung cancer therapy.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Findings&lt;/h3&gt;&lt;div&gt;MWCNT-based drug delivery demonstrates significant potential in improving lung cancer treatment by enabling targeted drug transport to cancer cells, thereby enhancing therapeutic efficacy. The controlled release of drugs from MWCNTs helps minimize systemic toxicity, ultimately improving patient safety and treatment outcomes. However, several challenges and limitations must be addressed before clinical implementation. Toxicity remains a primary concern, as MWCNTs may trigger inflammatory responses or accumulate in tissues, leading to potential long-term adverse effects. Additionally, the biocompatibility and overall safety of these nanocarriers require further validation through rigorous preclinical testing. Looking ahead, extensive research is essential to develop clinically viable MWCNT-based drug delivery systems. Further advancements in surface modifications and biodegradability enhancements are necessary to reduce ","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"7 ","pages":"Article 100180"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144170339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nano-coolants for thermal enhancement in heat exchangers: A review of prospects, challenges and applications","authors":"E.T. Bello ,&nbsp;A. Nasir ,&nbsp;A.S. Abdulkareem ,&nbsp;M.M. Muhammadu ,&nbsp;N.A. Musa ,&nbsp;J.O. Tijani ,&nbsp;Samson Oluwaseyi Bada","doi":"10.1016/j.nxnano.2025.100214","DOIUrl":"10.1016/j.nxnano.2025.100214","url":null,"abstract":"<div><div>The demand for efficient thermal systems has driven significant interest in nano-coolants due to their superior thermal properties as alternatives to traditional coolants like water, ethylene glycol (EG), synthetic oils (polyalphaolefins), and refrigerants (R134a, R410A). These coolants face operational and environmental challenges, including low heat transfer capacity, corrosion, toxicity and ecological effects that limit their efficiency under ideal conditions because of their poor thermophysical properties, which hinder their deployment. This review provides a comprehensive analysis of the prospects, challenges and applications of nano-coolants in various heat exchanger systems. Nanoparticles such as Al₂O_3, ZnO, Fe₃O_4, SiO₂ and CNTs are evaluated for their ability to enhance thermal conductivity, stability and heat transfer performance, with key factors influencing thermal enhancement, including size, shape, concentration and preparation methods, being critically examined. The study highlights applications across different heat exchanger configurations, including shell and tube, plate, double pipe, microchannel and spiral heat exchangers, which are evaluated through experimental and numerical results. Performance metrics such as Nusselt number, Reynolds number, heat transfer coefficient and overall heat transfer coefficient are discussed. In addition, the review addresses technical challenges, including agglomeration sedimentation, toxicity, increased viscosity and environmental impact, hindering widespread adoption. Furthermore, it outlines emerging prospects, including life cycle assessment, integration with renewablelar energy and the use of artificial intelligence and machine learning for predictive modeling and optimization, offering sustainable pathways for deployment and system miniaturization. The review demonstrates that, despite challenges, nano-coolants can effectively and efficiently enhance thermal exchange, impacting heat exchanger designs across various industries.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"8 ","pages":"Article 100214"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144633505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synergistic effects of Bi-metal oxide–graphene oxide nanocomposites in photodegradation applications","authors":"Govindarajalu Kishore ,&nbsp;Periyasamy Pritha ,&nbsp;S. Xavier ,&nbsp;D. Bhakiaraj ,&nbsp;Francisxavier Paularokiadoss ,&nbsp;Christian A. Celaya ,&nbsp;Mohammad Mansoob Khan","doi":"10.1016/j.nxnano.2025.100208","DOIUrl":"10.1016/j.nxnano.2025.100208","url":null,"abstract":"<div><div>The present study focuses on synthesizing two graphene-based composites, GO/CaO and GO/BaO, for photodegradation applications towards the methylene blue dye. The polycrystalline nature of the composites was determined by the XRD analysis with an average crystalline size of 14.9 nm. Raman analysis and FT-IR spectral analysis were used to determine the interaction between GO and the metal oxides. The optical band gap was evaluated to be 3.2 eV and 4.2 eV, with an absorbance λ_max of around 242 nm. The PL analysis confirms the electron mobility within the composites with an emission peak of 694 nm. The elemental composition and chemical state of the composites were evaluated using XPS analysis, providing valid results for the C1s peak at 284 eV, which corresponds to the C-C and C<img>C bonds. The photocatalytic degradation of the dye molecule was investigated by utilizing natural sunlight as the irradiation source to assess the practical applicability of the synthesized composites. The maximum degradation percentage achieved by the GO/CaO was 90 % with a period of 120 min under natural sunlight, showing a promising catalyst with a cost-effective and environmentally friendly composite for real-world wastewater treatment.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"8 ","pages":"Article 100208"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144522307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advances in bridging computational and clinical outcomes in brain tumour therapy by leveraging artificial intelligence and machine learning","authors":"Sagar Trivedi ,&nbsp;Ujban Hussain ,&nbsp;Samiksha Tammewar ,&nbsp;Rishabh Agade ,&nbsp;D.C. Sahu","doi":"10.1016/j.nxnano.2025.100235","DOIUrl":"10.1016/j.nxnano.2025.100235","url":null,"abstract":"<div><div>Brain tumours represent a significant therapeutic challenge due to their high complexity, aggressive nature, and protective obstacle posed by the blood-brain barrier (BBB). Among these, GBM emerges as the most aggressive and treatment-resistant variety of brain tumours. With current therapies, limitations arise while combating rapid progression and tumour heterogeneity coupled with poor drug delivery across the BBB. This review demonstrates how the confluence of drug discovery, together with the recent advancement of computer-aided drug design (CADD), artificial intelligence (AI), and machine learning (ML), is revolutionizing the discovery and therapeutic approach towards brain tumours, especially Glioblastoma Multiforme (GBM). Our work systematically examines CADD methodologies that enable accelerated discovery of therapeutic compounds, optimization of drug-target interactions, and enhanced BBB permeability. Particular focus in this review is placed on the AI and ML contributions to refining predictive models for drug efficacy and BBB penetration so that highly targeted, personalized therapies are developed. This review also covers a few unique challenges specific to GBM, how the tumour microenvironment influences resistance, how multi-targeted approaches would be critical, and the discussion of combination therapies. This review offers a comprehensive synthesis of recent advances integrating AI/ML, CADD, and network pharmacology for GBM therapy an interdisciplinary perspective that is still emerging in current literature. By highlighting recent successes and outlining promising directions, this review underscores the potential of CADD, AI, and ML to revolutionize brain tumour therapy, offering hope for improved outcomes in treating one of the most challenging cancers.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"8 ","pages":"Article 100235"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144750478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Colocasia esculenta leaf extracted cobalt oxide nanoparticles: A comprehensive investigation of the microstructural, morphological, antibacterial, and photocatalytic activity","authors":"Md. Estabrak Ahammod Sakib ,&nbsp;Md. Lael Hasan ,&nbsp;Hridoy Roy ,&nbsp;Md. Mahfujul Hasan ,&nbsp;Md. Mintu Ali","doi":"10.1016/j.nxnano.2025.100215","DOIUrl":"10.1016/j.nxnano.2025.100215","url":null,"abstract":"<div><div>This research was carried out to explore the biosynthesized cobalt oxide nanoparticles (Co₃O₄ NPs) for biomedical and environmental applications by using <em>Colocasia esculenta</em> (Taro) leaf extract. Herein, the synthesized nanoparticles were then characterized through several analytical techniques, such as x-ray diffraction (XRD), scanning electron microscopy (SEM), fourier transform infrared spectroscopy (FTIR), energy dispersive spectroscopy (EDS), and uv–visible spectroscopy. The crystallographic nature of prepared cobalt oxide NPs was largely confirmed by XRD analysis, with an average crystallite size of 18.233918 nm. Later, the SEM micrograph revealed spherical shape nanoparticles (22.26654 nm ± 0.17983 nm) dispersed throughout the surface area. EDS ensured the presence of existing elements in the composition. The absorbance peak at 212.5 nm and the energy band gap of 5.46 eV were noted by the uv–visible analysis, The antibacterial activity of the prepared NPs was evaluated against gram-positive (<em>Staphylococcus aureus, Bacillus subtilis</em>) and gram-negative (<em>Pseudomonas aeruginosa, E. coli</em>) bacteria, which demolished the bacterial cell by increasing the zone of inhibition area. Besides, the photocatalytic activity of <span><math><mrow><msub><mrow><mi>Co</mi></mrow><mrow><mn>3</mn></mrow></msub><msub><mrow><mi>O</mi></mrow><mrow><mn>4</mn></mrow></msub></mrow></math></span> NPs for an organic dye (Methylene Blue) degradation reached 86.40 % within 90 min, which may be recommended to mitigate related industrial contamination problems. This exploration also suggested that synthesized Co₃O₄ could be a promising material for photocatalytic dye degradation.</div></div>","PeriodicalId":100959,"journal":{"name":"Next Nanotechnology","volume":"8 ","pages":"Article 100215"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144632315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}