{"title":"Inteligencia artificial generativa en la población infantojuvenil: desafíos para el neurodesarrollo, la salud mental y la protección digital. Propuestas de actuación clínica y preventiva","authors":"M.A. Salmerón Ruiz, M. Fernández-Andújar","doi":"10.1016/j.med.2026.08.002","DOIUrl":"10.1016/j.med.2026.08.002","url":null,"abstract":"<div><div>Generative artificial intelligence (GAI) is rapidly transforming the digital environment of childhood and adolescence It affects learning processes, access to information, and patterns of interaction with digital environments, with significant implications for biopsychoemotional health and well-being. This phenomenon is unfolding in a context where professionals and families lack the necessary training to promote the ethical, safe, and responsible use of these technologies. This article provides an update to the existing literature on the risks associated with the use of GAI among the adolescent population, with a particular focus on its impact on neurodevelopment, physical and mental health, privacy, and safety online. Finally, it proposes clinical, educational, and regulatory courses of action aimed at strengthening protection by design and by default as well as for incorporating mechanisms for contextualized moderation or early detection of harmful conversations. Furthermore, this article advocates for improving digital education for families and professionals and for advancing public policies that protect the right to neurodevelopment and health and safeguard children and adolescents from emerging risks that arise from GAI.</div></div>","PeriodicalId":100912,"journal":{"name":"Medicine - Programa de Formación Médica Continuada Acreditado","volume":"14 61","pages":"Pages 3769-3778"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148917346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Protocolo de atención pediátrica ante la sospecha de abuso sexual infantil en España","authors":"F. Guerrero Alzola, G. del Pozo Gómez","doi":"10.1016/j.med.2026.08.005","DOIUrl":"10.1016/j.med.2026.08.005","url":null,"abstract":"<div><div>Sexual abuse in childhood and adolescence is a social and structural problem that affects public health and requires a coordinated healthcare response, with an approach that is sensitive to the trauma the child has experienced and focused on protecting the child. This protocol summarizes the initial clinical management in both emergency departments and pediatric/primary care settings: triage and stabilization, a brief neutral interview, a respectful physical examination, indications and time windows for collecting forensic samples, screening for and prevention of sexually transmitted infections (STI) (including post-exposure prophylaxis for HIV), emergency contraception, vaccination (hepatitis B virus <em>–</em>HBV<em>–</em>/human papillomavirus <em>–</em>HPV<em>–</em>), and a biopsychosocial follow-up plan. It includes practical guidelines based on the time elapsed since the incidents and pubertal age, as well as an operational algorithm that prioritizes health and safety needs over legal considerations. It emphasizes the duty to communicate with the Juvenile Court/Prosecutor's Office, when appropriate, and to coordinate with forensic units in accordance with the common protocols of the National Health System. The objective is to provide students and residents with a brief, practical tool that is consistent with current national and international guidelines.</div></div>","PeriodicalId":100912,"journal":{"name":"Medicine - Programa de Formación Médica Continuada Acreditado","volume":"14 61","pages":"Pages 3797-3802"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148924847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A.F. Fernández Romero, A.J. Ferrantelli Blanco, N. Bassy Iza, V.E. Landaeta Ribera, H.D. Villa Alvarado, P.M. Duluc Escobar
{"title":"Paciente mujer de 82 años, hipertensa, diabética con EPOC y fibrilación auricular que ingresa por neumonía por gripe A","authors":"A.F. Fernández Romero, A.J. Ferrantelli Blanco, N. Bassy Iza, V.E. Landaeta Ribera, H.D. Villa Alvarado, P.M. Duluc Escobar","doi":"10.1016/j.med.2026.09.009","DOIUrl":"10.1016/j.med.2026.09.009","url":null,"abstract":"","PeriodicalId":100912,"journal":{"name":"Medicine - Programa de Formación Médica Continuada Acreditado","volume":"14 62","pages":"Pages 3880.e1-3880.e4"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149072240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L.D. Mujica Chumbes, I. Rodríguez-Miñón, E. Martín Alcalde, L.M. Boscán Guevara, M.C. de Aguilar Caro, D. Pascual
{"title":"Protocolo de optimización farmacoterapéutica y deprescripción","authors":"L.D. Mujica Chumbes, I. Rodríguez-Miñón, E. Martín Alcalde, L.M. Boscán Guevara, M.C. de Aguilar Caro, D. Pascual","doi":"10.1016/j.med.2026.09.007","DOIUrl":"10.1016/j.med.2026.09.007","url":null,"abstract":"<div><div>Population aging is accompanied by an increase in multimorbidity and polypharmacy. This increases the risk of potentially inappropriate prescribing, drug interactions, and adverse events in older adults. In this context, pharmacotherapy optimization and deprescribing have emerged as fundamental strategies for improving the safety, appropriateness, and effectiveness of treatments in geriatrics.</div><div>This protocol proposes a structured, multidisciplinary approach to identifying inappropriate polypharmacy and implementing safe, person-centered deprescribing processes. It addresses practical strategies for the gradual suspension of medications, clinical follow-up, and outcome monitoring, including the emerging role of artificial intelligence and pharmacogenomics as supportive tools. The ultimate goal is to reduce unnecessary medication burden, minimize drug-related risks, and improve quality of life for older adult patients.</div></div>","PeriodicalId":100912,"journal":{"name":"Medicine - Programa de Formación Médica Continuada Acreditado","volume":"14 62","pages":"Pages 3867-3872"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149072238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J.J. Arechederra Calderón, A.F. Fernández Romero, M. Madrigal López, A. Alises García-Morato, C. Rodríguez Román, J. Castillejo Nuñez
{"title":"Protocolos de intervención en sarcopenia y recuperación funcional","authors":"J.J. Arechederra Calderón, A.F. Fernández Romero, M. Madrigal López, A. Alises García-Morato, C. Rodríguez Román, J. Castillejo Nuñez","doi":"10.1016/j.med.2026.09.006","DOIUrl":"10.1016/j.med.2026.09.006","url":null,"abstract":"<div><div>Sarcopenia is a geriatric syndrome characterized by the progressive and generalized loss of muscle mass, strength, and function. Its prevalence increases with age and is associated with frailty, falls, disability, and mortality. Understanding its pathophysiological mechanisms has enabled the development of therapeutic strategies aimed at preserving functionality and quality of life in older adults.</div><div>The objective of this protocol is to review the main treatment interventions aimed at preventing and treating sarcopenia and at maintaining or recuperating function in older adults. Addressing sarcopenia requires integrated, personalized strategies that combine exercise, nutrition, and, in selected cases, pharmacotherapy. Early detection and functional rehabilitation are key to preventing dependence and promoting active and healthy aging.</div></div>","PeriodicalId":100912,"journal":{"name":"Medicine - Programa de Formación Médica Continuada Acreditado","volume":"14 62","pages":"Pages 3862-3866"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149072237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"«Hoy, no me puedo concentrar». El desafío del abordaje integral en el adolescente","authors":"M. Pérez Pascual","doi":"10.1016/j.med.2026.08.009","DOIUrl":"10.1016/j.med.2026.08.009","url":null,"abstract":"","PeriodicalId":100912,"journal":{"name":"Medicine - Programa de Formación Médica Continuada Acreditado","volume":"14 61","pages":"Pages 3816.e1-3816.e3"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148924850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Nieto Fernández, D.F. Febres Panez, E. Espinosa Gimeno, A. Alises García-Morato, J. Castillejo Núñez, C. Rodríguez Román
{"title":"Deterioro cognitivo y demencia: hacia la detección precoz. Biomarcadores en líquido y pruebas neuropsicológicas digitales. Nuevos tratamientos modificadores de la enfermedad e intervenciones digitales","authors":"I. Nieto Fernández, D.F. Febres Panez, E. Espinosa Gimeno, A. Alises García-Morato, J. Castillejo Núñez, C. Rodríguez Román","doi":"10.1016/j.med.2026.09.002","DOIUrl":"10.1016/j.med.2026.09.002","url":null,"abstract":"<div><div>Cognitive impairment and dementia are common neurological syndromes associated with aging with a growing impact on clinical practice. This update reviews the main advances in the detection and management of cognitive impairment with a special focus on biomarkers and cognitive assessment tools. It describes the biological basis of the most prevalent forms of dementia and the role of plasma biomarkers, highlighting phosphorylated tau (particularly p-tau217) along with GFAP, Aβ42/40, and light neurofilament as aids in diagnosis and etiological characterization. It also analyzes digital neuropsychological tests, such as the <em>Digital Clock and Recall and the Digital Clock Drawing Test, which allow for an objective</em> and standardized assessment of various cognitive domains. The article also discusses currently available disease-modifying treatments for Alzheimer's disease and the main digital interventions used in mild cognitive impairment and dementia.</div></div>","PeriodicalId":100912,"journal":{"name":"Medicine - Programa de Formación Médica Continuada Acreditado","volume":"14 62","pages":"Pages 3826-3834"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149072233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Hernández García, B. Calvo Llorente, M. Vacas Córdoba, M.J. Zamoro Lorenci, G. Rojo Marcos
{"title":"Infecciones víricas emergentes. Arbovirus","authors":"G. Hernández García, B. Calvo Llorente, M. Vacas Córdoba, M.J. Zamoro Lorenci, G. Rojo Marcos","doi":"10.1016/j.med.2026.06.019","DOIUrl":"10.1016/j.med.2026.06.019","url":null,"abstract":"<div><div>The name arbovirus comes from the term <em>“arthropod-borne virus</em>” (viruses transmitted by arthropods, especially mosquitoes). It includes infections that are spreading due to climate change, globalization, and the adaptation of mosquito vectors, such as <em>Aedes aegypti</em> and <em>Aedes albopictus</em>.</div><div>The term “ChikDenMaZika syndrome” has been coined to denote the common symptoms shared by infections caused by the Chikungunya virus (CHIKV), dengue virus (DENV), Mayaro virus (MAYV), and Zika virus (ZIKV), given the pattern of coinfection and co-circulation in South America. Some of these arboviruses share similar symptoms (fever, muscle pain, rashes), but they also present more severe specific complications such as the risk of hemorrhage and death with DENV, severe fetal malformations with ZIKV, and chronic, disabling arthralgia with CHIKV.</div><div>From a public health perspective, arboviruses pose a complex and growing challenge to public health, with the emergence of autochthonous cases in Europe and Spain, where sporadic outbreaks have already been detected.</div></div>","PeriodicalId":100912,"journal":{"name":"Medicine - Programa de Formación Médica Continuada Acreditado","volume":"14 58","pages":"Pages 13535-13546"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148573393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Vacas Córdoba, M. Novella Mena, B. Calvo Llorente, M. Irigoyen Muñoz, M.J. Zamoro Lorenci
{"title":"Protocolo diagnóstico de las micosis pulmonares endémicas","authors":"M. Vacas Córdoba, M. Novella Mena, B. Calvo Llorente, M. Irigoyen Muñoz, M.J. Zamoro Lorenci","doi":"10.1016/j.med.2026.06.026","DOIUrl":"10.1016/j.med.2026.06.026","url":null,"abstract":"<div><div>Endemic pulmonary mycoses are difficult to diagnose due to their great clinical variability. Early clinical suspicion is essential for reaching a correct diagnosis that allows for the initiation of appropriate treatment, thereby avoiding unnecessary courses of antibiotics. The key to guiding the diagnosis lies in integrating clinical findings with the epidemiological history, considering the patient's origin and potential environmental risk exposures. Mycological culture is the gold standard diagnostic method, although its sensitivity varies and obtaining definitive results may take weeks. Therefore, non-culture-based tests such as antigen detection in blood and urine, serological tests, and molecular techniques are essential for reaching a diagnosis in many cases.</div></div>","PeriodicalId":100912,"journal":{"name":"Medicine - Programa de Formación Médica Continuada Acreditado","volume":"14 58","pages":"Pages 13600-13606"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148573750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Suárez-Hormiga, C. Betancort-Plata, C. Carranza-Rodríguez, C. Lavilla-Salgado, N. Jaén-Sánchez, J.L. Pérez-Arellano
{"title":"Protocolo diagnóstico y terapéutico de las parasitosis con afectación hepática y/o biliar","authors":"L. Suárez-Hormiga, C. Betancort-Plata, C. Carranza-Rodríguez, C. Lavilla-Salgado, N. Jaén-Sánchez, J.L. Pérez-Arellano","doi":"10.1016/j.med.2026.06.033","DOIUrl":"10.1016/j.med.2026.06.033","url":null,"abstract":"<div><div>The liver and biliary tract, which play a key role in metabolism and toxin elimination, can be affected by various parasitic infections. They can generate anything from asymptomatic conditions to severe diseases. Their rich vascularization facilitates systemic dissemination of the parasites and their connection to the spleen can lead to splenomegaly due to portal hypertension. Lesions are classified as diffuse (such as hepatomegaly or cytolysis) and focal (abscesses or cysts) and they are caused by direct invasion, obstruction, immune response, or cellular depletion. Among diffuse parasitic infections without portal hypertension, malaria and visceral leishmaniasis stand out, while schistosomiasis is typically associated with portal hypertension. <em>Echinococcus granulosus</em> and <em>Entamoeba histolytica</em> cause focal liver lesions. Several parasites can affect the biliary system, causing cholangitis or cholecystitis. Specifically, some trematodes such as <em>Fasciola</em> spp., <em>Clonorchis</em> spp., and <em>Opisthorchis</em> spp. can give rise to chronic cholangitis and progress to cirrhosis. The diagnosis is based on the detection of eggs in feces, serology, polymerase chain reaction, and imaging studies. Treatment includes antiparasitic drugs and surgery or endoscopy.</div></div>","PeriodicalId":100912,"journal":{"name":"Medicine - Programa de Formación Médica Continuada Acreditado","volume":"14 59","pages":"Pages 3669-3674"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148574660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}