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Gestante de 26 semanas con diátesis hemorrágica a estudio
Medicine - Programa de Formación Médica Continuada Acreditado Pub Date : 2024-11-01 DOI: 10.1016/j.med.2024.11.018
A. Mendoza Martínez, J.M. Martín de Bustamante González-Iglesias, V. Jiménez Yuste
{"title":"Gestante de 26 semanas con diátesis hemorrágica a estudio","authors":"A. Mendoza Martínez, J.M. Martín de Bustamante González-Iglesias, V. Jiménez Yuste","doi":"10.1016/j.med.2024.11.018","DOIUrl":"10.1016/j.med.2024.11.018","url":null,"abstract":"","PeriodicalId":100912,"journal":{"name":"Medicine - Programa de Formación Médica Continuada Acreditado","volume":"14 22","pages":"Pages 1335.e1-1335.e4"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143141402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Protocolo diagnóstico de las poliglobulias 多发性球状红细胞症诊断方案
Medicine - Programa de Formación Médica Continuada Acreditado Pub Date : 2024-11-01 DOI: 10.1016/j.med.2024.11.007
L. Medina de Alba, R. Mas Babío, J. Martínez-López, G. Carreño Gómez-Tarragona
{"title":"Protocolo diagnóstico de las poliglobulias","authors":"L. Medina de Alba,&nbsp;R. Mas Babío,&nbsp;J. Martínez-López,&nbsp;G. Carreño Gómez-Tarragona","doi":"10.1016/j.med.2024.11.007","DOIUrl":"10.1016/j.med.2024.11.007","url":null,"abstract":"<div><div>Polycythemia, or erythrocytosis, is an increase in hemoglobin or erythrocyte mass. An increase is considered present when there is more than 16.5<!--> <!-->g/dL of hemoglobin in males and more than 16<!--> <!-->g/dL in females. Erythropoietin produced in the kidneys is responsible for regulating erythropoiesis. Polycythemia vera is the most prominent primary or erythropoietin-independent erythrocytosis; secondary or erythropoietin-dependent erythrocytosis is due to multiple causes. The etiological diagnosis of polycythemia is essential for the treatment and follow-up of these patients.</div></div>","PeriodicalId":100912,"journal":{"name":"Medicine - Programa de Formación Médica Continuada Acreditado","volume":"14 21","pages":"Pages 1266-1269"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142706620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anemias hemolíticas adquiridas y congénitas 获得性和先天性溶血性贫血
Medicine - Programa de Formación Médica Continuada Acreditado Pub Date : 2024-11-01 DOI: 10.1016/j.med.2024.11.004
A. García Sánchez, A. Tamayo Soto, J. Martínez-López, M.T. Cedena Romero
{"title":"Anemias hemolíticas adquiridas y congénitas","authors":"A. García Sánchez,&nbsp;A. Tamayo Soto,&nbsp;J. Martínez-López,&nbsp;M.T. Cedena Romero","doi":"10.1016/j.med.2024.11.004","DOIUrl":"10.1016/j.med.2024.11.004","url":null,"abstract":"<div><div>Hemolytic anemias are a heterogeneous group of diseases characterized by a decrease in red blood cell survival (hemolysis). They are regenerative anemias (reticulocytosis) not justified by bleeding or recent correction of maturation factors deficits and which show signs of accelerated erythrocyte destruction, such as increased indirect bilirubin and lactate dehydrogenase (LDH) and decreased haptoglobin as well as morphological abnormalities on a peripheral blood smear. There are multiple causes of hemolytic anemia, including both acute and chronic congenital and acquired diseases. They are of varying potential severity. The intensity of the clinical signs and symptoms depends on the degree and speed of anemia onset. A good etiological diagnosis is fundamental in order to establish the proper treatment, given that each requires specific management.</div></div>","PeriodicalId":100912,"journal":{"name":"Medicine - Programa de Formación Médica Continuada Acreditado","volume":"14 21","pages":"Pages 1243-1254"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142706623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enfermedades de la hemostasia primaria
Medicine - Programa de Formación Médica Continuada Acreditado Pub Date : 2024-11-01 DOI: 10.1016/j.med.2024.11.011
S.C. Galván Platas, A. Mendoza Martínez, P.G. González Marugán, V. Jiménez Yuste
{"title":"Enfermedades de la hemostasia primaria","authors":"S.C. Galván Platas,&nbsp;A. Mendoza Martínez,&nbsp;P.G. González Marugán,&nbsp;V. Jiménez Yuste","doi":"10.1016/j.med.2024.11.011","DOIUrl":"10.1016/j.med.2024.11.011","url":null,"abstract":"<div><div>This update focuses on disorders that affect the vascular endothelium and platelets, key components in primary hemostasis. These are classified into purpura, which involves vascular abnormalities, and quantitative or qualitative platelet abnormalities, both of which can be congenital or acquired. The most common hemorrhagic symptoms include cutaneous and mucosal bleeding following trauma or surgery. Some congenital coagulation disorders are part of more complex syndromes that go beyond hemorrhagic symptoms and require a multidisciplinary approach. It is crucial to take a detailed medical history and perform a thorough physical examination when faced with any coagulation disorder. Platelet function tests and molecular diagnostic techniques are important additional tools. Regarding treatment, bleeding complications are treated in many cases according to their severity with desmopressin, antifibrinolytic agents, platelet transfusion, recombinant activated factor VII, and thrombopoietin receptor agonists. In some cases of congenital origin, allogeneic transplantation of hematopoietic progenitors is the only curative option. In acquired forms, treatment will generally be for the underlying disease itself.</div></div>","PeriodicalId":100912,"journal":{"name":"Medicine - Programa de Formación Médica Continuada Acreditado","volume":"14 22","pages":"Pages 1288-1298"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143141395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Varón de 71 años pluripatológico que consulta por bicitopenia 71 岁男性，患有多种疾病，因双血细胞减少症就诊。
Medicine - Programa de Formación Médica Continuada Acreditado Pub Date : 2024-11-01 DOI: 10.1016/j.med.2024.10.027
M. Callejas Charavía, P. García Ramírez
{"title":"Varón de 71 años pluripatológico que consulta por bicitopenia","authors":"M. Callejas Charavía,&nbsp;P. García Ramírez","doi":"10.1016/j.med.2024.10.027","DOIUrl":"10.1016/j.med.2024.10.027","url":null,"abstract":"","PeriodicalId":100912,"journal":{"name":"Medicine - Programa de Formación Médica Continuada Acreditado","volume":"14 20","pages":"Pages 1214.e1-1214.e3"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142663701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Protocolo diagnóstico de la anemia en el paciente anciano 老年患者贫血诊断方案
Medicine - Programa de Formación Médica Continuada Acreditado Pub Date : 2024-11-01 DOI: 10.1016/j.med.2024.10.023
D. Conde-Royo , J. Aspa-Cilleruelo
{"title":"Protocolo diagnóstico de la anemia en el paciente anciano","authors":"D. Conde-Royo ,&nbsp;J. Aspa-Cilleruelo","doi":"10.1016/j.med.2024.10.023","DOIUrl":"10.1016/j.med.2024.10.023","url":null,"abstract":"<div><div>Anemia in older adult patients is not only a disease with a high incidence that directly affects patients’ health, but it also behaves as a catalyst of other cardiovascular, functional, and cognitive comorbidities. It can also be a determining factor in these patients’ quality of life. The initial focus is mainly based on the study of iron metabolism and other basic analytical components according to the degree of anemia and mean corpuscular volume. The vast majority of cases can be controlled by replenishing potential deficits or treating underlying diseases, although this protocol also addresses purely hematological causes.</div></div>","PeriodicalId":100912,"journal":{"name":"Medicine - Programa de Formación Médica Continuada Acreditado","volume":"14 20","pages":"Pages 1193-1197"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142663671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Protocolo diagnóstico de las anemias hemolíticas 溶血性贫血诊断方案
Medicine - Programa de Formación Médica Continuada Acreditado Pub Date : 2024-11-01 DOI: 10.1016/j.med.2024.11.005
A. Tamayo Soto, A. García Sánchez, J. Martínez-López, M.T. Cedena Romero
{"title":"Protocolo diagnóstico de las anemias hemolíticas","authors":"A. Tamayo Soto,&nbsp;A. García Sánchez,&nbsp;J. Martínez-López,&nbsp;M.T. Cedena Romero","doi":"10.1016/j.med.2024.11.005","DOIUrl":"10.1016/j.med.2024.11.005","url":null,"abstract":"<div><div>Hemolytic anemias are defined by the premature destruction of circulating red blood cells. They can be classified as congenital or acquired and most are of immune origin. Diagnosis requires a comprehensive medical history, including a personal and family history; use of drugs or toxins; and a series of laboratory tests. Test findings predominantly show a marked decrease in hemoglobin; an increase in reticulocytes, bilirubin (indirect fraction), and lactate dehydrogenase; and a decrease in haptoglobin. Finally, a direct antiglobulin test (direct Coombs test) and a peripheral blood smear can be very useful in indicating the possible cause of hemolytic anemia.</div></div>","PeriodicalId":100912,"journal":{"name":"Medicine - Programa de Formación Médica Continuada Acreditado","volume":"14 21","pages":"Pages 1255-1259"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142706622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Varón de 46 años con orinas oscuras e infección por SARS-CoV-2 46 岁男性，深色尿液和 SARS-CoV-2 感染。
Medicine - Programa de Formación Médica Continuada Acreditado Pub Date : 2024-11-01 DOI: 10.1016/j.med.2024.11.009
E. Parra Virto, M. Sánchez Tabernero, J. Martínez-López, M.T. Cedena Romero, I. Zamanillo Herreros
{"title":"Varón de 46 años con orinas oscuras e infección por SARS-CoV-2","authors":"E. Parra Virto,&nbsp;M. Sánchez Tabernero,&nbsp;J. Martínez-López,&nbsp;M.T. Cedena Romero,&nbsp;I. Zamanillo Herreros","doi":"10.1016/j.med.2024.11.009","DOIUrl":"10.1016/j.med.2024.11.009","url":null,"abstract":"","PeriodicalId":100912,"journal":{"name":"Medicine - Programa de Formación Médica Continuada Acreditado","volume":"14 21","pages":"Pages 1274.e1-1274.e3"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142706532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Protocolo diagnóstico de la trombofilia
Medicine - Programa de Formación Médica Continuada Acreditado Pub Date : 2024-11-01 DOI: 10.1016/j.med.2024.11.015
J.M. Martín de Bustamante González-Iglesias, A. Mendoza Martínez, G. Maortua Langdon, V. Jiménez Yuste
{"title":"Protocolo diagnóstico de la trombofilia","authors":"J.M. Martín de Bustamante González-Iglesias,&nbsp;A. Mendoza Martínez,&nbsp;G. Maortua Langdon,&nbsp;V. Jiménez Yuste","doi":"10.1016/j.med.2024.11.015","DOIUrl":"10.1016/j.med.2024.11.015","url":null,"abstract":"<div><div>Thrombophilias are inherited or acquired conditions that predispose individuals to the occurrence of thrombotic events. However, prothrombotic environmental risk factors and family history often play a more important role in the genesis and management of a thrombotic event than the presence of thrombophilia. Therefore, a thrombophilia study should be performed only in cases in which the therapeutic approach will be modified according to the results. This remains controversial at present; multiple clinical guidelines have altered their indications as the criteria for indefinite anticoagulation have changed. Currently, the indication for performing hereditary or acquired thrombophilia studies is reserved only for very specific situations.</div></div>","PeriodicalId":100912,"journal":{"name":"Medicine - Programa de Formación Médica Continuada Acreditado","volume":"14 22","pages":"Pages 1323-1326"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143141399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Protocolo diagnóstico de las anemias microcíticas, normocíticas y macrocíticas 小红细胞、正常红细胞和大红细胞性贫血诊断方案
Medicine - Programa de Formación Médica Continuada Acreditado Pub Date : 2024-11-01 DOI: 10.1016/j.med.2024.11.006
M. Navarro Sánchez, J. Martínez-López, R. Colmenares Gil
{"title":"Protocolo diagnóstico de las anemias microcíticas, normocíticas y macrocíticas","authors":"M. Navarro Sánchez,&nbsp;J. Martínez-López,&nbsp;R. Colmenares Gil","doi":"10.1016/j.med.2024.11.006","DOIUrl":"10.1016/j.med.2024.11.006","url":null,"abstract":"<div><div>Anemia is a highly prevalent clinical condition with multiple etiologies. An adequate diagnostic algorithm is necessary to identify its cause in order to establish adequate treatment. The process of making an etiological diagnosis of anemias begins with a suitable case history and physical examination as well as the careful interpretation of the different hemocytometric indices in addition to the morphological findings of a peripheral blood smear and an analysis of biochemical parameters. The rest of the additional tests depend on the diagnostic suspicion and clinical scenario. On the other hand, it is essential to identify situations in which the finding of anemia is a medical emergency and requires immediate action.</div></div>","PeriodicalId":100912,"journal":{"name":"Medicine - Programa de Formación Médica Continuada Acreditado","volume":"14 21","pages":"Pages 1260-1265"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142706621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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